Cell Death & Disease

Papers
(The median citation count of Cell Death & Disease is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Correction: NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation587
GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila461
Correction: Adipose-derived mesenchymal stromal cells promote corneal wound healing by accelerating the clearance of neutrophils in cornea458
Correction: Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis427
Adding pieces to the puzzle of differentiated-to-anaplastic thyroid cancer evolution: the oncogene E2F7407
Correction: TRPM8 contributes to liver regeneration via mitochondrial energy metabolism mediated by PGC1α320
The Janus face of endogenous neuronal tPA: promoting self-protection and worsening the death of neighboring neurons304
ZBTB7B is a permissive regulator of hepatocellular carcinoma initiation by repressing c-Jun expression and function278
DNAJA4 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma via PSMD2-mediated MYH9 degradation254
KLF13 promotes esophageal cancer progression and regulates triacylglyceride and free fatty acid metabolism through GPIHBP1253
MAGI3 enhances sensitivity to sunitinib in renal cell carcinoma by suppressing the MAS/ERK axis and serves as a prognostic marker250
Single-cell RNA-seq and pathological phenotype reveal the functional atlas and precise roles of Sox30 in testicular cell development and differentiation228
KDM1A epigenetically enhances RAD51 expression to suppress the STING-associated anti-tumor immunity in esophageal squamous cell carcinoma225
miR-28-based combination therapy impairs aggressive B cell lymphoma growth by rewiring DNA replication214
Migration deficits of the neural crest caused by CXADR triplication in a human Down syndrome stem cell model209
RNAi-based ALOX15B silencing augments keratinocyte inflammation in vitro via EGFR/STAT1/JAK1 signalling204
Therapeutic efficacy of TMTP1-modified EVs in overcoming bone metastasis and immune resistance in PIK3CA mutant NSCLC195
Differential kinetics of splenic CD169+ macrophage death is one underlying cause of virus infection fate regulation190
FTO/IGF2BP2-mediated N6 methyladenosine modification in invasion and metastasis of thyroid carcinoma via CDH12189
ER-mitochondria association negatively affects wound healing by regulating NLRP3 activation187
TRAIL protects the immature lung from hyperoxic injury184
CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3173
Nuclear factor I-C disrupts cellular homeostasis between autophagy and apoptosis via miR-200b-Ambra1 in neural tube defects166
Glucose deprivation triggers DCAF1-mediated inactivation of Rheb-mTORC1 and promotes cancer cell survival162
Lysine methyltransferase SMYD2 inhibits antiviral innate immunity by promoting IRF3 dephosphorylation157
PD-L1 induces autophagy and primary resistance to EGFR–TKIs in EGFR-mutant lung adenocarcinoma via the MAPK signaling pathway155
RNF115/BCA2 deficiency alleviated acute liver injury in mice by promoting autophagy and inhibiting inflammatory response150
USP11-mediated LSH deubiquitination inhibits ferroptosis in colorectal cancer through epigenetic activation of CYP24A1147
FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression146
Radiotherapy remodels the tumor microenvironment for enhancing immunotherapeutic sensitivity144
Mitochondrial Drp1 recognizes and induces excessive mPTP opening after hypoxia through BAX-PiC and LRRK2-HK2142
The multifaceted role of Fragile X-Related Protein 1 (FXR1) in cellular processes: an updated review on cancer and clinical applications142
Tripartite motif 25 ameliorates doxorubicin-induced cardiotoxicity by degrading p85α142
p63, a key regulator of Ago2, links to the microRNA-144 cluster141
Hypoxia-responsive circRNAs: A novel but important participant in non-coding RNAs ushered toward tumor hypoxia137
Genetic alterations of Keap1 confers chemotherapeutic resistance through functional activation of Nrf2 and Notch pathway in head and neck squamous cell carcinoma135
Pivotal role of IL-8 derived from the interaction between osteosarcoma and tumor-associated macrophages in osteosarcoma growth and metastasis via the FAK pathway132
Ferroptotic MSCs protect mice against sepsis via promoting macrophage efferocytosis132
METTL16 controls Kaposi’s sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle132
PRMT1-mediated EZH2 methylation promotes breast cancer cell proliferation and tumorigenesis130
MESH1 knockdown triggers proliferation arrest through TAZ repression129
Single-cell sequencing resolves the landscape of immune cells and regulatory mechanisms in HIV-infected immune non-responders127
CAR-T therapy dilemma and innovative design strategies for next generation126
Targeting FAM111B attenuates mitophagy and increases the sensitivity to lenvatinib treatment by increasing MFN2 stability in hepatocellular carcinoma125
CircPSD3 aggravates tumor progression by maintaining TCA cycle and mitochondrial function via regulating SUCLG2 in thyroid carcinoma122
ZC3H13 mediates N6-methyladenosine modification of SNTB1 to promote epithelial-mesenchymal transition in gastric cancer122
ATRA upregulates OTUD6B to recruit CD8+ T cells to suppress colorectal liver metastasis by stabilizing DDX5/STAT3/CXCL11 axis120
Phosphorylation of USP33 by CDK1 stabilizes the mTORC2 component SIN1119
Macrophages downregulate NEDD9 to counteract S. Typhimurium- mediated FAK-AKT activation and lysosome inhibition118
NEDD4L binds the proteasome and promotes autophagy and bortezomib sensitivity in multiple myeloma116
Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibition116
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation116
Multi-omics prediction of axillary treatment response and tumour microenvironment alterations in lymph node-positive luminal breast cancer116
Enhancing cell death in B-cell malignancies through targeted inhibition of Bcl-3116
TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway115
Tulp1 deficiency causes early-onset retinal degeneration through affecting ciliogenesis and activating ferroptosis in zebrafish113
m5C-dependent cross-regulation between nuclear reader ALYREF and writer NSUN2 promotes urothelial bladder cancer malignancy through facilitating RABL6/TK1 mRNAs splicing and stabilization110
BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma109
An integrated bioinformatic investigation of mitochondrial solute carrier family 25 (SLC25) in colon cancer followed by preliminary validation of member 5 (SLC25A5) in tumorigenesis109
Underlying mechanisms of glucocorticoid-induced β-cell death and dysfunction: a new role for glycogen synthase kinase 3109
In vivo self-assembly and delivery of VEGFR2 siRNA-encapsulated small extracellular vesicles for lung metastatic osteosarcoma therapy109
Aryl hydrocarbon receptor dependent anti-inflammation and neuroprotective effects of tryptophan metabolites on retinal ischemia/reperfusion injury106
NADH:ubiquinone oxidoreductase core subunit S8 expression and functional significance in non-small cell lung cancer105
Nedd4-2 ablation in kidney improves glycaemic control in diabetic mice104
Defective hematopoietic differentiation of immune aplastic anemia patient-derived iPSCs104
Distinct functions of wild-type and R273H mutant Δ133p53α differentially regulate glioblastoma aggressiveness and therapy-induced senescence104
Knockdown of Porf-2 restores visual function after optic nerve crush injury103
SerpinB7 deficiency contributes to development of psoriasis via calcium-mediated keratinocyte differentiation dysfunction102
LINC00152 induced by TGF-β promotes metastasis via HuR in lung adenocarcinoma100
Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation99
Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop99
MicroRNA miR-20a-5p targets CYCS to inhibit apoptosis in hepatocellular carcinoma97
Therapeutic role of PTEN in tissue regeneration for management of neurological disorders: stem cell behaviors to an in-depth review96
Preservation of retinal structure and function in two mouse models of inherited retinal degeneration by ONL1204, an inhibitor of the Fas receptor95
Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma94
Regulatory T cells in skeletal muscle repair and regeneration: recent insights94
IGFBP2/ITGA5 promotes gefitinib resistance via activating STAT3/CXCL1 axis in non-small cell lung cancer94
FOXA1 prevents nutrients deprivation induced autophagic cell death through inducing loss of imprinting of IGF2 in lung adenocarcinoma93
Zipper-interacting protein kinase mediates neuronal cell death and cognitive dysfunction in traumatic brain injury via regulating DEDD92
BRISC is required for optimal activation of NF-κB in Kupffer cells induced by LPS and contributes to acute liver injury91
Dominant-negative p53-overexpression in skeletal muscle induces cell death and fiber atrophy in rats90
SOX4-BMI1 axis promotes non-small cell lung cancer progression and facilitates angiogenesis by suppressing ZNF2490
p53-loss induced prostatic epithelial cell plasticity and invasion is driven by a crosstalk with the tumor microenvironment89
Long noncoding RNA LINC01594 inhibits the CELF6-mediated splicing of oncogenic CD44 variants to promote colorectal cancer metastasis88
Mitochondria-derived H2O2 triggers liver regeneration via FoxO3a signaling pathway after partial hepatectomy in mice85
JUND/linc00976 promotes cholangiocarcinoma progression and metastasis, inhibits ferroptosis by regulating the miR-3202/GPX4 axis85
UPF1 contributes to the maintenance of endometrial cancer stem cell phenotype by stabilizing LINC0096385
Overexpression of EphB6 and EphrinB2 controls soma spacing of cortical neurons in a mutual inhibitory way84
Identification of multiple organ metastasis-associated hub mRNA/miRNA signatures in non-small cell lung cancer84
Pharmacological inhibition of Ref-1 enhances the therapeutic sensitivity of papillary thyroid carcinoma to vemurafenib83
A novel protein encoded by circUBE4B promotes progression of esophageal squamous cell carcinoma by augmenting MAPK/ERK signaling83
USP1 modulates hepatocellular carcinoma progression via the Hippo/TAZ axis82
The role of SPATA2 in TNF signaling, cancer, and spermatogenesis82
LAPTM4B-mediated hepatocellular carcinoma stem cell proliferation and MDSC migration: implications for HCC progression and sensitivity to PD-L1 monoclonal antibody therapy81
METTL3-mediated m6A modification of LINC00839 maintains glioma stem cells and radiation resistance by activating Wnt/β-catenin signaling80
GBA1-dependent membrane glucosylceramide reprogramming promotes liver cancer metastasis via activation of the Wnt/β-catenin signalling pathway80
USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma78
ATF4/CEMIP/PKCα promotes anoikis resistance by enhancing protective autophagy in prostate cancer cells78
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC78
Leveraging glycosylation for early detection and therapeutic target discovery in pancreatic cancer78
Correction: Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells76
Endothelial ETS1 inhibition exacerbate blood–brain barrier dysfunction in multiple sclerosis through inducing endothelial-to-mesenchymal transition75
RNA helicase DDX5 modulates sorafenib sensitivity in hepatocellular carcinoma via the Wnt/β-catenin–ferroptosis axis75
CYP1B1 inhibits ferroptosis and induces anti-PD-1 resistance by degrading ACSL4 in colorectal cancer75
PAF1 cooperates with YAP1 in metaplastic ducts to promote pancreatic cancer75
Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG174
A novel inhibitor of the mitochondrial respiratory complex I with uncoupling properties exerts potent antitumor activity73
The regulation, function, and role of lipophagy, a form of selective autophagy, in metabolic disorders72
m6A and m5C modification of GPX4 facilitates anticancer immunity via STING activation71
Functional delivery of lncRNA TUG1 by endothelial progenitor cells derived extracellular vesicles confers anti-inflammatory macrophage polarization in sepsis via impairing miR-9-5p-targeted SIRT1 inhi70
CD36 aggravates podocyte injury by activating NLRP3 inflammasome and inhibiting autophagy in lupus nephritis69
IL-17A injury to retinal ganglion cells is mediated by retinal Müller cells in diabetic retinopathy69
FAK mediates LPS-induced inflammatory lung injury through interacting TAK1 and activating TAK1-NFκB pathway69
Correction to: Deubiquitylase OTUD6B stabilizes the mutated pVHL and suppresses cell migration in clear cell renal cell carcinoma68
PRMT1 methylation of WTAP promotes multiple myeloma tumorigenesis by activating oxidative phosphorylation via m6A modification of NDUFS668
SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice68
PRMT1-mediated methylation of UBE2m promoting calcium oxalate crystal-induced kidney injury by inhibiting fatty acid metabolism67
Angiotensin II related glial cell activation and necroptosis of retinal ganglion cells after systemic hypotension in glaucoma67
MLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL1067
Nerve growth factor promotes lysyl oxidase-dependent chondrosarcoma cell metastasis by suppressing miR-149-5p synthesis67
Retraction Note: Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer67
Correction to: Tumor-associated macrophage-derived exosomes transmitting miR-193a-5p promote the progression of renal cell carcinoma via TIMP2-dependent vasculogenic mimicry66
TRIM26 deficiency enhancing liver regeneration through macrophage polarization and β-catenin pathway activation66
Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2 recruitment onto mitochondria and PARK2-PARK6 activity during mitophagy66
The kinase activity of integrin-linked kinase regulates cellular senescence in gastric cancer66
Novel roles of luteinizing hormone (LH) in tissue regeneration-associated functions in endometrial stem cells66
Nek2A prevents centrosome clustering and induces cell death in cancer cells via KIF2C interaction66
Retraction Note: Long noncoding RNA LINC01234 promotes serine hydroxymethyltransferase 2 expression and proliferation by competitively binding miR-642a-5p in colon cancer65
Reduced protection of RIPK3-deficient mice against influenza by matrix protein 2 ectodomain targeted active and passive vaccination strategies65
Balancing the functions of DNA extracellular traps in intracellular parasite infections: implications for host defense, disease pathology and therapy65
Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss65
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer64
Loss of RNF41 promotes bladder cancer metastasis through increasing NUDC stability to enhance tubulin polymerization64
Transglutaminase 2 associated with PI3K and PTEN in a membrane-bound signalosome platform blunts cell death64
Repurposing MDM2 inhibitor RG7388 for TP53-mutant NSCLC: a p53-independent pyroptotic mechanism via ROS/p-p38/NOXA/caspase-3/GSDME axis64
LncRNA SNHG1 regulates neuroblastoma cell fate via interactions with HDAC1/264
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway64
Card9 protects sepsis by regulating Ripk2-mediated activation of NLRP3 inflammasome in macrophages63
A novel Hoxd13 mutation causes synpolydactyly and promotes osteoclast differentiation by regulating pSmad5/p65/c-Fos/Rank axis63
CD146 regulates the stemness and chemoresistance of hepatocellular carcinoma via JAG2-NOTCH signaling63
TAB182 aggravates progression of esophageal squamous cell carcinoma by enhancing β-catenin nuclear translocation through FHL2 dependent manner62
Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans62
Innate and adaptive immune cell interaction drives inflammasome activation and hepatocyte apoptosis in murine liver injury from immune checkpoint inhibitors62
SMOC2 promotes an epithelial-mesenchymal transition and a pro-metastatic phenotype in epithelial cells of renal cell carcinoma origin62
Downregulation of TPX2 impairs the antitumor activity of CD8+ T cells in hepatocellular carcinoma62
Retraction Note to: Expansion of monocytic myeloid-derived suppressor cells ameliorated intestinal inflammatory response by radiation through SOCS3 expression62
Role of cardiolipins, mitochondria, and autophagy in the differentiation process activated by all-trans retinoic acid in acute promyelocytic leukemia62
Downregulated liver-elevated long intergenic noncoding RNA (LINC02428) is a tumor suppressor that blocks KDM5B/IGF2BP1 positive feedback loop in hepatocellular carcinoma62
The role of vitamin K and its antagonist in the process of ferroptosis-damaged RPE-mediated CNV62
Hepatic steatosis and pyroptosis are induced by the hepatitis B virus X protein via B56α-METTL3 interaction-mediated m6A modification of the NLRP3 mRNA61
Nitroglycerin: a comprehensive review in cancer therapy61
Cancer-associated fibroblasts expressing FSTL3 promote vasculogenic mimicry formation and drive colon cancer malignancy61
USP14/S100A11 axis promote colorectal cancer progression by inhibiting cell senescence61
IRE1α translational suppression potentiates STING-dependent chemoresistance in pancreatic cancer60
Protein kinase G inhibition preserves photoreceptor viability and function in a new mouse model for autosomal dominant retinitis pigmentosa60
Histone methyltransferase Smyd2 drives adipogenesis via regulating STAT3 phosphorylation60
High dose androgen suppresses natural killer cytotoxicity of castration-resistant prostate cancer cells via altering AR/circFKBP5/miRNA-513a-5p/PD-L1 signals60
Acetylation-dependent USP7-TRIM25 axis drives oncogenic progression in non-small cell lung cancer60
Androgen-targeted hsa_circ_0085121 encodes a novel protein and improves the development of prostate cancer through facilitating the activity of PI3K/Akt/mTOR pathway and enhancing AR-V7 alternative sp60
Exosomal circTGFBR2 promotes hepatocellular carcinoma progression via enhancing ATG5 mediated protective autophagy60
The feedback loop between MTA1 and MTA3/TRIM21 modulates stemness of breast cancer in response to estrogen59
A novel function of STAT3β in suppressing interferon response improves outcome in acute myeloid leukemia59
MLK4 regulates DNA damage response and promotes triple-negative breast cancer chemoresistance59
Nuclear pore protein POM121 regulates subcellular localization and transcriptional activity of PPARγ59
MicroRNA miR-1275 coordinately regulates AEA/LPA signals via targeting FAAH in lipid metabolism reprogramming of gastric cancer59
β‐arrestin 2 negatively regulates lung cancer progression by inhibiting the TRAF6 signaling axis for NF-κB activation and autophagy induced by TLR3 and TLR459
Critical analysis of translational potential of rodent models of white matter pathology across a wide spectrum of human diseases59
NAT10 mediates TLR2 to promote podocyte senescence in adriamycin-induced nephropathy58
Inhibitory role of proguanil on the growth of bladder cancer via enhancing EGFR degradation and inhibiting its downstream signaling pathway to induce autophagy58
Systemic mechanisms of necrotic cell debris clearance58
Metabolic gatekeepers: harnessing tumor-derived metabolites to optimize T cell-based immunotherapy efficacy in the tumor microenvironment58
Tim-3+ decidual Mφs induced Th2 and Treg bias in decidual CD4+T cells and promoted pregnancy maintenance via CD13258
Galectin-3 promotes secretion of proteases that decrease epithelium integrity in human colon cancer cells57
Central Zika virus infection causes hypothalamic inflammation and persistent insulin resistance in adult mice57
E3 Ubiquitin ligases Cbl-b and c-Cbl maintain the homeostasis of macrophages by regulating the M-CSF/M-CSFR signaling axis57
BNIP3 (BCL2 interacting protein 3) regulates pluripotency by modulating mitochondrial homeostasis via mitophagy57
Ascitic fluid shear stress in concert with hepatocyte growth factor drive stemness and chemoresistance of ovarian cancer cells via the c-Met-PI3K/Akt-miR-199a-3p signaling pathway57
Genome-wide identification of microRNA targets reveals positive regulation of the Hippo pathway by miR-122 during liver development57
RIPK3 promoter hypermethylation in hepatocytes protects from bile acid-induced inflammation and necroptosis57
Opposing roles for GSK3β and ERK1-dependent phosphorylation of huntingtin during neuronal dysfunction and cell death in Huntington’s disease57
Transcription factor EB-mediated mesenchymal stem cell therapy induces autophagy and alleviates spinocerebellar ataxia type 3 defects in neuronal cells model57
SUMOylation of PDPK1 Is required to maintain glycolysis-dependent CD4 T-cell homeostasis56
MiR-122-5p regulates the mevalonate pathway by targeting p53 in non-small cell lung cancer56
Correction: MicroRNA-29a induces loss of 5-hydroxymethylcytosine and promotes metastasis of hepatocellular carcinoma through a TET–SOCS1–MMP9 signaling axis56
USP7 promotes temozolomide resistance by stabilizing MGMT in glioblastoma56
Single-cell multi-omics analysis reveals cancer regulatory elements of transcriptional programs and clinical implications56
S1PR3-driven positive feedback loop sustains STAT3 activation and keratinocyte hyperproliferation in psoriasis56
Circulating miR-184 is a potential predictive biomarker of cardiac damage in Anderson–Fabry disease56
The mitochondrial ATP-dependent potassium channel (mitoKATP) controls skeletal muscle structure and function56
Chemotoxicity-induced exosomal lncFERO regulates ferroptosis and stemness in gastric cancer stem cells56
YAP1 facilitates the pathogenesis of psoriasis via modulating keratinocyte proliferation and inflammation55
STING dependent BAX-IRF3 signaling results in apoptosis during late-stage Coxiella burnetii infection55
CircNEIL3 mediates pyroptosis to influence lung adenocarcinoma radiotherapy by upregulating PIF1 through miR-1184 inhibition55
Tumor-associated macrophage-derived exosomes transmitting miR-193a-5p promote the progression of renal cell carcinoma via TIMP2-dependent vasculogenic mimicry55
LncRNA FIRRE functions as a tumor promoter by interaction with PTBP1 to stabilize BECN1 mRNA and facilitate autophagy55
Germline specific genes increase DNA double-strand break repair and radioresistance in lung adenocarcinoma cells55
Wet-dry-wet drug screen leads to the synthesis of TS1, a novel compound reversing lung fibrosis through inhibition of myofibroblast differentiation55
GSDMD-dependent neutrophil extracellular traps promote macrophage-to-myofibroblast transition and renal fibrosis in obstructive nephropathy54
TNFAIP2 promotes HIF1α transcription and breast cancer angiogenesis by activating the Rac1-ERK-AP1 signaling axis54
O-GlcNAcylation inhibition redirects the response of colon cancer cells to chemotherapy from senescence to apoptosis54
p21-activated kinase 4 controls the aggregation of α-synuclein by reducing the monomeric and aggregated forms of α-synuclein: involvement of the E3 ubiquitin ligase NEDD4-154
DDX5 deficiency drives non-canonical NF-κB activation and NRF2 expression, influencing sorafenib response and hepatocellular carcinoma progression54
Trim21-mediated CCT2 ubiquitination suppresses malignant progression and promotes CD4+T cell activation in breast cancer53
Deficiency of PPP6C protects TNF-induced necroptosis through activation of TAK153
Aldolase B-driven lactagenesis and CEACAM6 activation promote cell renewal and chemoresistance in colorectal cancer through the Warburg effect53
Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis53
Glycolysis-related lncRNA TMEM105 upregulates LDHA to facilitate breast cancer liver metastasis via sponging miR-120853
TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC453
Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia53
Exosomes derived from mesenchymal stem cells in diabetes and diabetic complications52
PAK6 rescues pathogenic LRRK2-mediated ciliogenesis and centrosomal cohesion defects in a mutation-specific manner52
Hepatocyte DDX3X protects against drug-induced acute liver injury via controlling stress granule formation and oxidative stress52
Stanniocalcin 1 promotes lung metastasis of breast cancer by enhancing EGFR–ERK–S100A4 signaling52
The ALDH2/PolG2 axis enhances mitochondrial biogenesis via transcriptional regulation of Nrf2 and promotes chemotherapy resistance in acute myeloid leukaemia51
TP63 as a modulator of ferroptosis in TP53 mutations glioblastoma51
Correction: SETD8 inhibits apoptosis and ferroptosis of Ewing’s sarcoma through YBX1/RAC3 axis51
CENPT prevents renal cell carcinoma against ferroptosis by enhancing the synthesis of glutathione51
Generation of functional neurons from adult human mucosal olfactory ensheathing glia by direct lineage conversion51
Inhibition of ATM enhances the immunogenicity of triple-negative breast cancer by promoting MHC-I expression51
The CRTC-CREB axis functions as a transcriptional sensor to protect against proteotoxic stress in Drosophila50
LINC00924-induced fatty acid metabolic reprogramming facilitates gastric cancer peritoneal metastasis via hnRNPC-regulated alternative splicing of Mnk250
Correction: Tumor-educated B cells promote renal cancer metastasis via inducing the IL-1β/HIF-2α/Notch1 signals50
Non-enzymatic role of SOD1 in intestinal stem cell growth49
Cerebral endothelial cell-derived extracellular vesicles regulate microglial polarization and promote autophagy via delivery of miR-672-5p49
CircLIFR suppresses hepatocellular carcinoma progression by sponging miR-624-5p and inactivating the GSK-3β/β-catenin signaling pathway49
Polymeric immunoglobulin receptor deficiency exacerbates autoimmune hepatitis by inducing intestinal dysbiosis and barrier dysfunction49
CAF-derived exosomal WEE2-AS1 facilitates colorectal cancer progression via promoting degradation of MOB1A to inhibit the Hippo pathway49
RBM4 regulates cellular senescence via miR1244/SERPINE1 axis49
Versatile enhancement of the killing potential of anti-cancer agents achieved by peptide mimetics of the PCNA interface towards specialized DNA polymerases49
YAP-dependent Wnt5a induction in hypertrophic adipocytes restrains adiposity48
The role of circular RNAs in regulating resistance to cancer immunotherapy: mechanisms and implications48
Autolysosomes and caspase-3 control the biogenesis and release of immunogenic apoptotic exosomes48
Claudin-7 is essential for the maintenance of colonic stem cell homoeostasis via the modulation of Wnt/Notch signalling48
Targeting the apoptosis pathway to treat tumours of the paediatric nervous system48
PARP1-catalyzed PARylation of YY1 mediates endoplasmic reticulum stress in granulosa cells to determine primordial follicle activation48
Exosomal circRNA BTG2 derived from RBP-J overexpressed-macrophages inhibits glioma progression via miR-25-3p/PTEN48
ETS-1-activated LINC01016 over-expression promotes tumor progression via suppression of RFFL-mediated DHX9 ubiquitination degradation in breast cancers48
Transglutaminase 2 function in glioblastoma tumor efferocytosis48
Retraction Note: RUNX3-regulated circRNA METTL3 inhibits colorectal cancer proliferation and metastasis via miR-107/PER3 axis47
Transcriptome reprogramming of Epstein-Barr virus infected epithelial and B cells reveals distinct host-virus interaction profiles47
The YTHDC1 reader protein recognizes and regulates the lncRNA MEG3 following its METTL3-mediated m6A methylation: a novel mechanism early during radiation-induced liver injury47
Correction to: Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells47
The duality of CXCR3 in glioblastoma: unveiling autocrine and paracrine mechanisms for novel therapeutic approaches47
WWC1/2 regulate spinogenesis and cognition in mice by stabilizing AMOT47
Correction to: ONECUT2 facilitates hepatocellular carcinoma metastasis by transcriptionally upregulating FGF2 and ACLY47
Selective deletion of E3 ubiquitin ligase FBW7 in VE-cadherin-positive cells instigates diffuse large B-cell lymphoma in mice in vivo47
Retraction Note: Identification of protein kinase inhibitors to reprogram breast cancer cells47
CSE reduces OTUD4 triggering lung epithelial cell apoptosis via PAI-1 degradation47
Bone marrow-independent adventitial macrophage progenitor cells contribute to angiogenesis47
Retraction Note: Involvement of autophagy in hypoxia-BNIP3 signaling to promote epidermal keratinocyte migration47
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