Cell Death & Disease

Article	Citations
GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila	670
Correction: Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis	533
Adding pieces to the puzzle of differentiated-to-anaplastic thyroid cancer evolution: the oncogene E2F7	481
The Janus face of endogenous neuronal tPA: promoting self-protection and worsening the death of neighboring neurons	464
p53-loss induced prostatic epithelial cell plasticity and invasion is driven by a crosstalk with the tumor microenvironment	441
The role of SPATA2 in TNF signaling, cancer, and spermatogenesis	364
Correction: Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells	336
Single-cell RNA-seq and pathological phenotype reveal the functional atlas and precise roles of Sox30 in testicular cell development and differentiation	317
Differential kinetics of splenic CD169+ macrophage death is one underlying cause of virus infection fate regulation	296
Therapeutic efficacy of TMTP1-modified EVs in overcoming bone metastasis and immune resistance in PIK3CA mutant NSCLC	296
p63, a key regulator of Ago2, links to the microRNA-144 cluster	286
Targeting FAM111B attenuates mitophagy and increases the sensitivity to lenvatinib treatment by increasing MFN2 stability in hepatocellular carcinoma	282
ZC3H13 mediates N6-methyladenosine modification of SNTB1 to promote epithelial-mesenchymal transition in gastric cancer	226
ATRA upregulates OTUD6B to recruit CD8+ T cells to suppress colorectal liver metastasis by stabilizing DDX5/STAT3/CXCL11 axis	222
Phosphorylation of USP33 by CDK1 stabilizes the mTORC2 component SIN1	221
Macrophages downregulate NEDD9 to counteract S. Typhimurium- mediated FAK-AKT activation and lysosome inhibition	220
Multi-omics prediction of axillary treatment response and tumour microenvironment alterations in lymph node-positive luminal breast cancer	207
TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway	207
Genetic alterations of Keap1 confers chemotherapeutic resistance through functional activation of Nrf2 and Notch pathway in head and neck squamous cell carcinoma	205
FOXA1 prevents nutrients deprivation induced autophagic cell death through inducing loss of imprinting of IGF2 in lung adenocarcinoma	198
TRAIL protects the immature lung from hyperoxic injury	192
ER-mitochondria association negatively affects wound healing by regulating NLRP3 activation	186
Knockdown of Porf-2 restores visual function after optic nerve crush injury	181
BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma	167
Defective hematopoietic differentiation of immune aplastic anemia patient-derived iPSCs	166

USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma	165
Identification of multiple organ metastasis-associated hub mRNA/miRNA signatures in non-small cell lung cancer	163
SerpinB7 deficiency contributes to development of psoriasis via calcium-mediated keratinocyte differentiation dysfunction	160
CircPSD3 aggravates tumor progression by maintaining TCA cycle and mitochondrial function via regulating SUCLG2 in thyroid carcinoma	158
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation	158
A high-throughput screening approach to discover potential colorectal cancer chemotherapeutics: repurposing drugs to identify novel disruptors of 14-3-3 proteins	157
Long noncoding RNA LINC01594 inhibits the CELF6-mediated splicing of oncogenic CD44 variants to promote colorectal cancer metastasis	156
miR-28-based combination therapy impairs aggressive B cell lymphoma growth by rewiring DNA replication	152
Overexpression of EphB6 and EphrinB2 controls soma spacing of cortical neurons in a mutual inhibitory way	151
Correction: NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation	150
Migration deficits of the neural crest caused by CXADR triplication in a human Down syndrome stem cell model	148
CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3	142
ZBTB7B is a permissive regulator of hepatocellular carcinoma initiation by repressing c-Jun expression and function	142
Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibition	141
Long non-coding RNAs in cancer glycolysis and metabolism: mechanisms and translational opportunities	140
Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma	138
Proteasome inhibition as a potential therapeutic target in thymic cancer	136
Lysine methyltransferase SMYD2 inhibits antiviral innate immunity by promoting IRF3 dephosphorylation	134
Pharmacological inhibition of Ref-1 enhances the therapeutic sensitivity of papillary thyroid carcinoma to vemurafenib	131
PD-L1 induces autophagy and primary resistance to EGFR–TKIs in EGFR-mutant lung adenocarcinoma via the MAPK signaling pathway	129
Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop	126
GBA1-dependent membrane glucosylceramide reprogramming promotes liver cancer metastasis via activation of the Wnt/β-catenin signalling pathway	125
LINC00152 induced by TGF-β promotes metastasis via HuR in lung adenocarcinoma	125
LAPTM4B-mediated hepatocellular carcinoma stem cell proliferation and MDSC migration: implications for HCC progression and sensitivity to PD-L1 monoclonal antibody therapy	123
NADH:ubiquinone oxidoreductase core subunit S8 expression and functional significance in non-small cell lung cancer	123
JUND/linc00976 promotes cholangiocarcinoma progression and metastasis, inhibits ferroptosis by regulating the miR-3202/GPX4 axis	122
Enhancing cell death in B-cell malignancies through targeted inhibition of Bcl-3	121
A novel protein encoded by circUBE4B promotes progression of esophageal squamous cell carcinoma by augmenting MAPK/ERK signaling	121
Nedd4-2 ablation in kidney improves glycaemic control in diabetic mice	121
Therapeutic role of PTEN in tissue regeneration for management of neurological disorders: stem cell behaviors to an in-depth review	120
KLF13 promotes esophageal cancer progression and regulates triacylglyceride and free fatty acid metabolism through GPIHBP1	119
PAF1 cooperates with YAP1 in metaplastic ducts to promote pancreatic cancer	119
KDM1A epigenetically enhances RAD51 expression to suppress the STING-associated anti-tumor immunity in esophageal squamous cell carcinoma	116
Dominant-negative p53-overexpression in skeletal muscle induces cell death and fiber atrophy in rats	114
NEDD4L binds the proteasome and promotes autophagy and bortezomib sensitivity in multiple myeloma	111
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC	111
RNA helicase DDX5 modulates sorafenib sensitivity in hepatocellular carcinoma via the Wnt/β-catenin–ferroptosis axis	110
Single-cell sequencing resolves the landscape of immune cells and regulatory mechanisms in HIV-infected immune non-responders	107
In vivo self-assembly and delivery of VEGFR2 siRNA-encapsulated small extracellular vesicles for lung metastatic osteosarcoma therapy	106
Tulp1 deficiency causes early-onset retinal degeneration through affecting ciliogenesis and activating ferroptosis in zebrafish	106
Regulatory T cells in skeletal muscle repair and regeneration: recent insights	106
PIM kinase inhibition attenuates pro-tumoral and immunosuppressive functions of macrophages in classic Hodgkin lymphoma	105
The multifaceted role of Fragile X-Related Protein 1 (FXR1) in cellular processes: an updated review on cancer and clinical applications	104
DNAJA4 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma via PSMD2-mediated MYH9 degradation	104
UPF1 contributes to the maintenance of endometrial cancer stem cell phenotype by stabilizing LINC00963	104
IGFBP2/ITGA5 promotes gefitinib resistance via activating STAT3/CXCL1 axis in non-small cell lung cancer	103
Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation	102
USP1 modulates hepatocellular carcinoma progression via the Hippo/TAZ axis	102
Ferroptotic MSCs protect mice against sepsis via promoting macrophage efferocytosis	99
RNF115/BCA2 deficiency alleviated acute liver injury in mice by promoting autophagy and inhibiting inflammatory response	97

An integrated bioinformatic investigation of mitochondrial solute carrier family 25 (SLC25) in colon cancer followed by preliminary validation of member 5 (SLC25A5) in tumorigenesis	97
Endothelial ETS1 inhibition exacerbate blood–brain barrier dysfunction in multiple sclerosis through inducing endothelial-to-mesenchymal transition	94
Hypoxia-responsive circRNAs: A novel but important participant in non-coding RNAs ushered toward tumor hypoxia	94
The N6-methyladenosine-mediated cLMNB1 degrades FGFR4 to overcome osimertinib resistance in non-small cell lung cancer	92
FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression	90
Glucose deprivation triggers DCAF1-mediated inactivation of Rheb-mTORC1 and promotes cancer cell survival	90
MAGI3 enhances sensitivity to sunitinib in renal cell carcinoma by suppressing the MAS/ERK axis and serves as a prognostic marker	90
RNAi-based ALOX15B silencing augments keratinocyte inflammation in vitro via EGFR/STAT1/JAK1 signalling	89
USP11-mediated LSH deubiquitination inhibits ferroptosis in colorectal cancer through epigenetic activation of CYP24A1	88
Tripartite motif 25 ameliorates doxorubicin-induced cardiotoxicity by degrading p85α	87
Stochasticity contributes to explaining minority and majority MOMP during apoptosis	87
ATF4/CEMIP/PKCα promotes anoikis resistance by enhancing protective autophagy in prostate cancer cells	86
PRMT1 methylation of WTAP promotes multiple myeloma tumorigenesis by activating oxidative phosphorylation via m6A modification of NDUFS6	86
BRISC is required for optimal activation of NF-κB in Kupffer cells induced by LPS and contributes to acute liver injury	86
MESH1 knockdown triggers proliferation arrest through TAZ repression	85
MicroRNA miR-20a-5p targets CYCS to inhibit apoptosis in hepatocellular carcinoma	84
The regulation, function, and role of lipophagy, a form of selective autophagy, in metabolic disorders	84
CD36 aggravates podocyte injury by activating NLRP3 inflammasome and inhibiting autophagy in lupus nephritis	84
Pivotal role of IL-8 derived from the interaction between osteosarcoma and tumor-associated macrophages in osteosarcoma growth and metastasis via the FAK pathway	83
FAK mediates LPS-induced inflammatory lung injury through interacting TAK1 and activating TAK1-NFκB pathway	82
Correction: TRPM8 contributes to liver regeneration via mitochondrial energy metabolism mediated by PGC1α	81
Aryl hydrocarbon receptor dependent anti-inflammation and neuroprotective effects of tryptophan metabolites on retinal ischemia/reperfusion injury	81
CYP1B1 inhibits ferroptosis and induces anti-PD-1 resistance by degrading ACSL4 in colorectal cancer	79
m5C-dependent cross-regulation between nuclear reader ALYREF and writer NSUN2 promotes urothelial bladder cancer malignancy through facilitating RABL6/TK1 mRNAs splicing and stabilization	78
m6A and m5C modification of GPX4 facilitates anticancer immunity via STING activation	77
METTL16 controls Kaposi’s sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle	76
Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1	74
A novel inhibitor of the mitochondrial respiratory complex I with uncoupling properties exerts potent antitumor activity	73
TPI1 enhances gemcitabine resistance in bladder cancer by promoting autophagy through activating Beclin-1	73
Mitochondria-derived H2O2 triggers liver regeneration via FoxO3a signaling pathway after partial hepatectomy in mice	72
Correction: Adipose-derived mesenchymal stromal cells promote corneal wound healing by accelerating the clearance of neutrophils in cornea	72
CAR-T therapy dilemma and innovative design strategies for next generation	72
Leveraging glycosylation for early detection and therapeutic target discovery in pancreatic cancer	71
Radiotherapy remodels the tumor microenvironment for enhancing immunotherapeutic sensitivity	71
Zipper-interacting protein kinase mediates neuronal cell death and cognitive dysfunction in traumatic brain injury via regulating DEDD	71
SOX4-BMI1 axis promotes non-small cell lung cancer progression and facilitates angiogenesis by suppressing ZNF24	71
METTL3-mediated m6A modification of LINC00839 maintains glioma stem cells and radiation resistance by activating Wnt/β-catenin signaling	71
FTO/IGF2BP2-mediated N6 methyladenosine modification in invasion and metastasis of thyroid carcinoma via CDH12	71
Preservation of retinal structure and function in two mouse models of inherited retinal degeneration by ONL1204, an inhibitor of the Fas receptor	70
Deficiency of PPP6C protects TNF-induced necroptosis through activation of TAK1	70
Correction to: Deubiquitylase OTUD6B stabilizes the mutated pVHL and suppresses cell migration in clear cell renal cell carcinoma	70
Retraction Note: Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer	70
SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice	70
Distinct functions of wild-type and R273H mutant Δ133p53α differentially regulate glioblastoma aggressiveness and therapy-induced senescence	70
Transcription factor EB-mediated mesenchymal stem cell therapy induces autophagy and alleviates spinocerebellar ataxia type 3 defects in neuronal cells model	70
The kinase activity of integrin-linked kinase regulates cellular senescence in gastric cancer	70
Retraction Note: Long noncoding RNA LINC01234 promotes serine hydroxymethyltransferase 2 expression and proliferation by competitively binding miR-642a-5p in colon cancer	69
Transglutaminase 2 associated with PI3K and PTEN in a membrane-bound signalosome platform blunts cell death	69
Loss of RNF41 promotes bladder cancer metastasis through increasing NUDC stability to enhance tubulin polymerization	69
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway	69
Central Zika virus infection causes hypothalamic inflammation and persistent insulin resistance in adult mice	69
Cancer-associated fibroblasts expressing FSTL3 promote vasculogenic mimicry formation and drive colon cancer malignancy	68
Germline specific genes increase DNA double-strand break repair and radioresistance in lung adenocarcinoma cells	68
Retraction Note to: Expansion of monocytic myeloid-derived suppressor cells ameliorated intestinal inflammatory response by radiation through SOCS3 expression	68
Single-cell multi-omics analysis reveals cancer regulatory elements of transcriptional programs and clinical implications	68
Androgen-targeted hsa_circ_0085121 encodes a novel protein and improves the development of prostate cancer through facilitating the activity of PI3K/Akt/mTOR pathway and enhancing AR-V7 alternative sp	68
IRE1α translational suppression potentiates STING-dependent chemoresistance in pancreatic cancer	67
The MYC-dependent lncRNA MB3 inhibits apoptosis in Group 3 Medulloblastoma by regulating the TGF-β pathway via HMGN5	67
Novel roles of luteinizing hormone (LH) in tissue regeneration-associated functions in endometrial stem cells	67
Histone methyltransferase Smyd2 drives adipogenesis via regulating STAT3 phosphorylation	67
Hepatic steatosis and pyroptosis are induced by the hepatitis B virus X protein via B56α-METTL3 interaction-mediated m6A modification of the NLRP3 mRNA	67
Downregulated liver-elevated long intergenic noncoding RNA (LINC02428) is a tumor suppressor that blocks KDM5B/IGF2BP1 positive feedback loop in hepatocellular carcinoma	67
NAT10 mediates TLR2 to promote podocyte senescence in adriamycin-induced nephropathy	67
TRIM26 deficiency enhancing liver regeneration through macrophage polarization and β-catenin pathway activation	67
MiR-122-5p regulates the mevalonate pathway by targeting p53 in non-small cell lung cancer	66
E3 Ubiquitin ligases Cbl-b and c-Cbl maintain the homeostasis of macrophages by regulating the M-CSF/M-CSFR signaling axis	66
The glycolytic enzyme PGK1 phosphorylates MORC2 to Confer radioresistance in pancreatic ductal adenocarcinoma	66
Angiotensin II related glial cell activation and necroptosis of retinal ganglion cells after systemic hypotension in glaucoma	65
Exosomal circTGFBR2 promotes hepatocellular carcinoma progression via enhancing ATG5 mediated protective autophagy	65
Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia	65
Nek2A prevents centrosome clustering and induces cell death in cancer cells via KIF2C interaction	65
Acetylation-dependent USP7-TRIM25 axis drives oncogenic progression in non-small cell lung cancer	64
Nuclear pore protein POM121 regulates subcellular localization and transcriptional activity of PPARγ	64
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer	63
p21-activated kinase 4 controls the aggregation of α-synuclein by reducing the monomeric and aggregated forms of α-synuclein: involvement of the E3 ubiquitin ligase NEDD4-1	63
S1PR3-driven positive feedback loop sustains STAT3 activation and keratinocyte hyperproliferation in psoriasis	63
Inhibitory role of proguanil on the growth of bladder cancer via enhancing EGFR degradation and inhibiting its downstream signaling pathway to induce autophagy	63
Galectin-3 promotes secretion of proteases that decrease epithelium integrity in human colon cancer cells	63
TNFAIP2 promotes HIF1α transcription and breast cancer angiogenesis by activating the Rac1-ERK-AP1 signaling axis	63
Matrix stiffness maintains bladder cancer stemness via integrin-nuclear skeleton axis	62

CD146 regulates the stemness and chemoresistance of hepatocellular carcinoma via JAG2-NOTCH signaling	62
Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss	61
Protein kinase G inhibition preserves photoreceptor viability and function in a new mouse model for autosomal dominant retinitis pigmentosa	61
Pharmacological activation of p53 induces dose-dependent changes in endothelial cell fate during angiogenic sprouting	61
Tim-3+ decidual Mφs induced Th2 and Treg bias in decidual CD4+T cells and promoted pregnancy maintenance via CD132	61
Balancing the functions of DNA extracellular traps in intracellular parasite infections: implications for host defense, disease pathology and therapy	61
MicroRNA miR-1275 coordinately regulates AEA/LPA signals via targeting FAAH in lipid metabolism reprogramming of gastric cancer	61
SMOC2 promotes an epithelial-mesenchymal transition and a pro-metastatic phenotype in epithelial cells of renal cell carcinoma origin	61
Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2 recruitment onto mitochondria and PARK2-PARK6 activity during mitophagy	61
USP14/S100A11 axis promote colorectal cancer progression by inhibiting cell senescence	61
RIPK3 promoter hypermethylation in hepatocytes protects from bile acid-induced inflammation and necroptosis	60
Downregulation of TPX2 impairs the antitumor activity of CD8+ T cells in hepatocellular carcinoma	60
LncRNA SNHG1 regulates neuroblastoma cell fate via interactions with HDAC1/2	60
The role of vitamin K and its antagonist in the process of ferroptosis-damaged RPE-mediated CNV	60
Hepatocyte DDX3X protects against drug-induced acute liver injury via controlling stress granule formation and oxidative stress	60
O-GlcNAcylation inhibition redirects the response of colon cancer cells to chemotherapy from senescence to apoptosis	59
MLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL10	59
Card9 protects sepsis by regulating Ripk2-mediated activation of NLRP3 inflammasome in macrophages	59
Critical analysis of translational potential of rodent models of white matter pathology across a wide spectrum of human diseases	59
The feedback loop between MTA1 and MTA3/TRIM21 modulates stemness of breast cancer in response to estrogen	59
Innate and adaptive immune cell interaction drives inflammasome activation and hepatocyte apoptosis in murine liver injury from immune checkpoint inhibitors	58
Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis	58
Opposing roles for GSK3β and ERK1-dependent phosphorylation of huntingtin during neuronal dysfunction and cell death in Huntington’s disease	58
Reduced protection of RIPK3-deficient mice against influenza by matrix protein 2 ectodomain targeted active and passive vaccination strategies	58
The emerging role of dendritic cells in the tumor microenvironment: from antigen presentation to targeted immunotherapy	58
Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans	58
Aldolase B-driven lactagenesis and CEACAM6 activation promote cell renewal and chemoresistance in colorectal cancer through the Warburg effect	58
TAB182 aggravates progression of esophageal squamous cell carcinoma by enhancing β-catenin nuclear translocation through FHL2 dependent manner	57
Correction: Mitochondrial quality control in diabetes mellitus and complications: molecular mechanisms and therapeutic strategies	57
A novel function of STAT3β in suppressing interferon response improves outcome in acute myeloid leukemia	57
Correction to: Tumor-associated macrophage-derived exosomes transmitting miR-193a-5p promote the progression of renal cell carcinoma via TIMP2-dependent vasculogenic mimicry	57
Role of cardiolipins, mitochondria, and autophagy in the differentiation process activated by all-trans retinoic acid in acute promyelocytic leukemia	57
CircNEIL3 mediates pyroptosis to influence lung adenocarcinoma radiotherapy by upregulating PIF1 through miR-1184 inhibition	56
SUMOylation of PDPK1 Is required to maintain glycolysis-dependent CD4 T-cell homeostasis	56
A novel Hoxd13 mutation causes synpolydactyly and promotes osteoclast differentiation by regulating pSmad5/p65/c-Fos/Rank axis	56
Correction: MicroRNA-29a induces loss of 5-hydroxymethylcytosine and promotes metastasis of hepatocellular carcinoma through a TET–SOCS1–MMP9 signaling axis	56
Stanniocalcin 1 promotes lung metastasis of breast cancer by enhancing EGFR–ERK–S100A4 signaling	56
High dose androgen suppresses natural killer cytotoxicity of castration-resistant prostate cancer cells via altering AR/circFKBP5/miRNA-513a-5p/PD-L1 signals	56
DDX5 deficiency drives non-canonical NF-κB activation and NRF2 expression, influencing sorafenib response and hepatocellular carcinoma progression	56
Tumor-associated macrophage-derived exosomes transmitting miR-193a-5p promote the progression of renal cell carcinoma via TIMP2-dependent vasculogenic mimicry	55
YAP1 facilitates the pathogenesis of psoriasis via modulating keratinocyte proliferation and inflammation	55
Systemic mechanisms of necrotic cell debris clearance	55
Unraveling sex differences in age-related hippocampal decline: differential mitochondrial dysfunction, Lonp1-dependent mitochondrial proteostasis and mtROS production in aged C57BL/6 mice	55
The mitochondrial ATP-dependent potassium channel (mitoKATP) controls skeletal muscle structure and function	55
LncRNA FIRRE functions as a tumor promoter by interaction with PTBP1 to stabilize BECN1 mRNA and facilitate autophagy	55
β‐arrestin 2 negatively regulates lung cancer progression by inhibiting the TRAF6 signaling axis for NF-κB activation and autophagy induced by TLR3 and TLR4	54
GSDMD-dependent neutrophil extracellular traps promote macrophage-to-myofibroblast transition and renal fibrosis in obstructive nephropathy	54
Glycolysis-related lncRNA TMEM105 upregulates LDHA to facilitate breast cancer liver metastasis via sponging miR-1208	54
Metabolic gatekeepers: harnessing tumor-derived metabolites to optimize T cell-based immunotherapy efficacy in the tumor microenvironment	54
Trim21-mediated CCT2 ubiquitination suppresses malignant progression and promotes CD4+T cell activation in breast cancer	54
BNIP3 (BCL2 interacting protein 3) regulates pluripotency by modulating mitochondrial homeostasis via mitophagy	53
Ascitic fluid shear stress in concert with hepatocyte growth factor drive stemness and chemoresistance of ovarian cancer cells via the c-Met-PI3K/Akt-miR-199a-3p signaling pathway	53
PRMT1-mediated methylation of UBE2m promoting calcium oxalate crystal-induced kidney injury by inhibiting fatty acid metabolism	53
Nitroglycerin: a comprehensive review in cancer therapy	53
Exosomes derived from mesenchymal stem cells in diabetes and diabetic complications	53
Correction: SETD8 inhibits apoptosis and ferroptosis of Ewing’s sarcoma through YBX1/RAC3 axis	52
Repurposing MDM2 inhibitor RG7388 for TP53-mutant NSCLC: a p53-independent pyroptotic mechanism via ROS/p-p38/NOXA/caspase-3/GSDME axis	52
Generation of functional neurons from adult human mucosal olfactory ensheathing glia by direct lineage conversion	52
STING dependent BAX-IRF3 signaling results in apoptosis during late-stage Coxiella burnetii infection	52
USP7 promotes temozolomide resistance by stabilizing MGMT in glioblastoma	52
TP63 as a modulator of ferroptosis in TP53 mutations glioblastoma	51
Intratumoral microbiota remodeling of the tumor microenvironment impact solid tumor immunotherapy	51
Retraction Note: Identification of protein kinase inhibitors to reprogram breast cancer cells	51
Retraction Note: RUNX3-regulated circRNA METTL3 inhibits colorectal cancer proliferation and metastasis via miR-107/PER3 axis	51
Endothelial cell-derived RSPO3 activates Gαi1/3-Erk signaling and protects neurons from ischemia/reperfusion injury	51
Versatile enhancement of the killing potential of anti-cancer agents achieved by peptide mimetics of the PCNA interface towards specialized DNA polymerases	51
Deficiency of SIAH1 promotes the formation of filopodia by increasing the accumulation of FASN in liver cancer	51
Correction to: Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells	51
Exosomal circRNA BTG2 derived from RBP-J overexpressed-macrophages inhibits glioma progression via miR-25-3p/PTEN	51
The ALDH2/PolG2 axis enhances mitochondrial biogenesis via transcriptional regulation of Nrf2 and promotes chemotherapy resistance in acute myeloid leukaemia	51
RBM4 regulates cellular senescence via miR1244/SERPINE1 axis	51
Retraction Note: Involvement of autophagy in hypoxia-BNIP3 signaling to promote epidermal keratinocyte migration	51
Selective deletion of E3 ubiquitin ligase FBW7 in VE-cadherin-positive cells instigates diffuse large B-cell lymphoma in mice in vivo	51
Hydroxyurea blunts mitochondrial energy metabolism and osteoblast and osteoclast differentiation exacerbating trabecular bone loss in sickle cell mice	50
ETS-1-activated LINC01016 over-expression promotes tumor progression via suppression of RFFL-mediated DHX9 ubiquitination degradation in breast cancers	50
PRL-mediated STAT5B/ARRB2 pathway promotes the progression of prostate cancer through the activation of MAPK signaling	50
LncRNA IRAR regulates chemokines production in tubular epithelial cells thus promoting kidney ischemia-reperfusion injury	50
Neuronal haemoglobin induces loss of dopaminergic neurons in mouse Substantia nigra, cognitive deficits and cleavage of endogenous α-synuclein	50
PSMA1 mediates tumor progression and poor prognosis of gastric carcinoma by deubiquitinating and stabilizing TAZ	50
The YTHDC1 reader protein recognizes and regulates the lncRNA MEG3 following its METTL3-mediated m6A methylation: a novel mechanism early during radiation-induced liver injury	50
Correction: Tumor-educated B cells promote renal cancer metastasis via inducing the IL-1β/HIF-2α/Notch1 signals	50
Loss of RhoA in microglia disables glycolytic adaptation and impairs spinal cord injury recovery through Arhgap25/HIF-1α pathway	50
Role of reactive oxygen species in regulating 27-hydroxycholesterol-induced apoptosis of hematopoietic progenitor cells and myeloid cell lines	50
Claudin-7 is essential for the maintenance of colonic stem cell homoeostasis via the modulation of Wnt/Notch signalling	49
LINC00924-induced fatty acid metabolic reprogramming facilitates gastric cancer peritoneal metastasis via hnRNPC-regulated alternative splicing of Mnk2	49
Cerebral endothelial cell-derived extracellular vesicles regulate microglial polarization and promote autophagy via delivery of miR-672-5p	49
CircLIFR suppresses hepatocellular carcinoma progression by sponging miR-624-5p and inactivating the GSK-3β/β-catenin signaling pathway	49
FRMD3 inhibits the growth and metastasis of breast cancer through the ubiquitination-mediated degradation of vimentin and subsequent impairment of focal adhesion	49
Novel FABP4+C1q+ macrophages enhance antitumor immunity and associated with response to neoadjuvant pembrolizumab and chemotherapy in NSCLC via AMPK/JAK/STAT axis	49
In vivo restoration of dystrophin expression in mdx mice using intra-muscular and intra-arterial injections of hydrogel microsphere carriers of exon skipping antisense oligonucleotides	49
WWC1/2 regulate spinogenesis and cognition in mice by stabilizing AMOT	49
Interaction of lncRNA LENT with DHX36 regulates translation and suppresses autophagy in melanoma	48
Neddylation-mediated degradation of hnRNPA2B1 contributes to hypertriglyceridemia pancreatitis	48
Acute liver failure-induced arginine deficiency impairs blood-brain barrier via inhibiting mTORC1-S6K1/4EBP1 pathway and inducing autophagy	48
Transglutaminase 2 function in glioblastoma tumor efferocytosis	48