Cell Death & Disease

Article	Citations
Adding pieces to the puzzle of differentiated-to-anaplastic thyroid cancer evolution: the oncogene E2F7	452
Correction: TRPM8 contributes to liver regeneration via mitochondrial energy metabolism mediated by PGC1α	400
The Janus face of endogenous neuronal tPA: promoting self-protection and worsening the death of neighboring neurons	376
FOXA1 prevents nutrients deprivation induced autophagic cell death through inducing loss of imprinting of IGF2 in lung adenocarcinoma	374
Dominant-negative p53-overexpression in skeletal muscle induces cell death and fiber atrophy in rats	355
Correction: Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells	267
Correction: Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis	253
Correction: Adipose-derived mesenchymal stromal cells promote corneal wound healing by accelerating the clearance of neutrophils in cornea	244
Single-cell RNA-seq and pathological phenotype reveal the functional atlas and precise roles of Sox30 in testicular cell development and differentiation	233
Differential kinetics of splenic CD169+ macrophage death is one underlying cause of virus infection fate regulation	215
ZBTB7B is a permissive regulator of hepatocellular carcinoma initiation by repressing c-Jun expression and function	203
Therapeutic efficacy of TMTP1-modified EVs in overcoming bone metastasis and immune resistance in PIK3CA mutant NSCLC	192
GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila	188
p53-loss induced prostatic epithelial cell plasticity and invasion is driven by a crosstalk with the tumor microenvironment	186
MESH1 knockdown triggers proliferation arrest through TAZ repression	184
Nedd4-2 ablation in kidney improves glycaemic control in diabetic mice	176
PD-L1 induces autophagy and primary resistance to EGFR–TKIs in EGFR-mutant lung adenocarcinoma via the MAPK signaling pathway	165
ATRA upregulates OTUD6B to recruit CD8+ T cells to suppress colorectal liver metastasis by stabilizing DDX5/STAT3/CXCL11 axis	165
MicroRNA miR-20a-5p targets CYCS to inhibit apoptosis in hepatocellular carcinoma	159
Mitochondrial Drp1 recognizes and induces excessive mPTP opening after hypoxia through BAX-PiC and LRRK2-HK2	158
Tulp1 deficiency causes early-onset retinal degeneration through affecting ciliogenesis and activating ferroptosis in zebrafish	157
Knockdown of Porf-2 restores visual function after optic nerve crush injury	157
PRMT1-mediated EZH2 methylation promotes breast cancer cell proliferation and tumorigenesis	153
Distinct functions of wild-type and R273H mutant Δ133p53α differentially regulate glioblastoma aggressiveness and therapy-induced senescence	151
Zipper-interacting protein kinase mediates neuronal cell death and cognitive dysfunction in traumatic brain injury via regulating DEDD	148

CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3	148
Glucose deprivation triggers DCAF1-mediated inactivation of Rheb-mTORC1 and promotes cancer cell survival	146
Aryl hydrocarbon receptor dependent anti-inflammation and neuroprotective effects of tryptophan metabolites on retinal ischemia/reperfusion injury	144
Phosphorylation of USP33 by CDK1 stabilizes the mTORC2 component SIN1	143
BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma	142
Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation	139
The tyrosine-kinase inhibitor Nintedanib ameliorates autosomal-dominant polycystic kidney disease	136
TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway	136
Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop	134
Nuclear factor I-C disrupts cellular homeostasis between autophagy and apoptosis via miR-200b-Ambra1 in neural tube defects	133
A novel protein encoded by circUBE4B promotes progression of esophageal squamous cell carcinoma by augmenting MAPK/ERK signaling	131
USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma	130
NADH:ubiquinone oxidoreductase core subunit S8 expression and functional significance in non-small cell lung cancer	129
Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibition	127
TRAIL protects the immature lung from hyperoxic injury	127
Defective hematopoietic differentiation of immune aplastic anemia patient-derived iPSCs	126
MAGI3 enhances sensitivity to sunitinib in renal cell carcinoma by suppressing the MAS/ERK axis and serves as a prognostic marker	126
miR-28-based combination therapy impairs aggressive B cell lymphoma growth by rewiring DNA replication	125
Lysine methyltransferase SMYD2 inhibits antiviral innate immunity by promoting IRF3 dephosphorylation	122
Apatinib inhibits glioma cell malignancy in patient-derived orthotopic xenograft mouse model by targeting thrombospondin 1/myosin heavy chain 9 axis	120
p63, a key regulator of Ago2, links to the microRNA-144 cluster	120
Long noncoding RNA LINC01594 inhibits the CELF6-mediated splicing of oncogenic CD44 variants to promote colorectal cancer metastasis	119
Macrophages downregulate NEDD9 to counteract S. Typhimurium- mediated FAK-AKT activation and lysosome inhibition	119
Migration deficits of the neural crest caused by CXADR triplication in a human Down syndrome stem cell model	115
Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma	112
PPFIBP1 induces glioma cell migration and invasion through FAK/Src/JNK signaling pathway	110
KDM1A epigenetically enhances RAD51 expression to suppress the STING-associated anti-tumor immunity in esophageal squamous cell carcinoma	110
RNAi-based ALOX15B silencing augments keratinocyte inflammation in vitro via EGFR/STAT1/JAK1 signalling	109
KLF13 promotes esophageal cancer progression and regulates triacylglyceride and free fatty acid metabolism through GPIHBP1	109
Hypoxia-responsive circRNAs: A novel but important participant in non-coding RNAs ushered toward tumor hypoxia	108
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation	108
LINC00152 induced by TGF-β promotes metastasis via HuR in lung adenocarcinoma	107
Enhancing cell death in B-cell malignancies through targeted inhibition of Bcl-3	106
IL-17A injury to retinal ganglion cells is mediated by retinal Müller cells in diabetic retinopathy	106
Overexpression of EphB6 and EphrinB2 controls soma spacing of cortical neurons in a mutual inhibitory way	104
Pivotal role of IL-8 derived from the interaction between osteosarcoma and tumor-associated macrophages in osteosarcoma growth and metastasis via the FAK pathway	101
SerpinB7 deficiency contributes to development of psoriasis via calcium-mediated keratinocyte differentiation dysfunction	101
Ferroptotic MSCs protect mice against sepsis via promoting macrophage efferocytosis	101
Endothelial ETS1 inhibition exacerbate blood–brain barrier dysfunction in multiple sclerosis through inducing endothelial-to-mesenchymal transition	100
Pharmacological inhibition of Ref-1 enhances the therapeutic sensitivity of papillary thyroid carcinoma to vemurafenib	98
FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression	97
Preservation of retinal structure and function in two mouse models of inherited retinal degeneration by ONL1204, an inhibitor of the Fas receptor	97
Tripartite motif 25 ameliorates doxorubicin-induced cardiotoxicity by degrading p85α	96
Single-cell sequencing resolves the landscape of immune cells and regulatory mechanisms in HIV-infected immune non-responders	95
Underlying mechanisms of glucocorticoid-induced β-cell death and dysfunction: a new role for glycogen synthase kinase 3	94
FTO/IGF2BP2-mediated N6 methyladenosine modification in invasion and metastasis of thyroid carcinoma via CDH12	93
Leveraging glycosylation for early detection and therapeutic target discovery in pancreatic cancer	93
USP1 modulates hepatocellular carcinoma progression via the Hippo/TAZ axis	93
DNAJA4 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma via PSMD2-mediated MYH9 degradation	92
The multifaceted role of Fragile X-Related Protein 1 (FXR1) in cellular processes: an updated review on cancer and clinical applications	92

Functional delivery of lncRNA TUG1 by endothelial progenitor cells derived extracellular vesicles confers anti-inflammatory macrophage polarization in sepsis via impairing miR-9-5p-targeted SIRT1 inhi	91
ER-mitochondria association negatively affects wound healing by regulating NLRP3 activation	91
GBA1-dependent membrane glucosylceramide reprogramming promotes liver cancer metastasis via activation of the Wnt/β-catenin signalling pathway	90
Regulatory T cells in skeletal muscle repair and regeneration: recent insights	90
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC	88
The role of SPATA2 in TNF signaling, cancer, and spermatogenesis	87
An integrated bioinformatic investigation of mitochondrial solute carrier family 25 (SLC25) in colon cancer followed by preliminary validation of member 5 (SLC25A5) in tumorigenesis	86
Therapeutic role of PTEN in tissue regeneration for management of neurological disorders: stem cell behaviors to an in-depth review	85
JUND/linc00976 promotes cholangiocarcinoma progression and metastasis, inhibits ferroptosis by regulating the miR-3202/GPX4 axis	84
Radiotherapy remodels the tumor microenvironment for enhancing immunotherapeutic sensitivity	83
Elaiophylin reduces body weight and lowers glucose levels in obese mice by activating AMPK	83
Identification of multiple organ metastasis-associated hub mRNA/miRNA signatures in non-small cell lung cancer	83
CAR-T therapy dilemma and innovative design strategies for next generation	82
Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1	81
USP11-mediated LSH deubiquitination inhibits ferroptosis in colorectal cancer through epigenetic activation of CYP24A1	81
UPF1 contributes to the maintenance of endometrial cancer stem cell phenotype by stabilizing LINC00963	81
RNA helicase DDX5 modulates sorafenib sensitivity in hepatocellular carcinoma via the Wnt/β-catenin–ferroptosis axis	81
A novel inhibitor of the mitochondrial respiratory complex I with uncoupling properties exerts potent antitumor activity	80
m6A and m5C modification of GPX4 facilitates anticancer immunity via STING activation	79
CYP1B1 inhibits ferroptosis and induces anti-PD-1 resistance by degrading ACSL4 in colorectal cancer	78
PAF1 cooperates with YAP1 in metaplastic ducts to promote pancreatic cancer	77
Genetic alterations of Keap1 confers chemotherapeutic resistance through functional activation of Nrf2 and Notch pathway in head and neck squamous cell carcinoma	76
LAPTM4B-mediated hepatocellular carcinoma stem cell proliferation and MDSC migration: implications for HCC progression and sensitivity to PD-L1 monoclonal antibody therapy	76
In vivo self-assembly and delivery of VEGFR2 siRNA-encapsulated small extracellular vesicles for lung metastatic osteosarcoma therapy	75
CD36 aggravates podocyte injury by activating NLRP3 inflammasome and inhibiting autophagy in lupus nephritis	75
BRISC is required for optimal activation of NF-κB in Kupffer cells induced by LPS and contributes to acute liver injury	75
RNF115/BCA2 deficiency alleviated acute liver injury in mice by promoting autophagy and inhibiting inflammatory response	74
ATF4/CEMIP/PKCα promotes anoikis resistance by enhancing protective autophagy in prostate cancer cells	74
m5C-dependent cross-regulation between nuclear reader ALYREF and writer NSUN2 promotes urothelial bladder cancer malignancy through facilitating RABL6/TK1 mRNAs splicing and stabilization	74
NEDD4L binds the proteasome and promotes autophagy and bortezomib sensitivity in multiple myeloma	74
Correction: NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation	74
SOX4-BMI1 axis promotes non-small cell lung cancer progression and facilitates angiogenesis by suppressing ZNF24	73
The regulation, function, and role of lipophagy, a form of selective autophagy, in metabolic disorders	72
METTL16 controls Kaposi’s sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle	72
PRMT1 methylation of WTAP promotes multiple myeloma tumorigenesis by activating oxidative phosphorylation via m6A modification of NDUFS6	71
Mitochondria-derived H2O2 triggers liver regeneration via FoxO3a signaling pathway after partial hepatectomy in mice	71
IGFBP2/ITGA5 promotes gefitinib resistance via activating STAT3/CXCL1 axis in non-small cell lung cancer	71
FAK mediates LPS-induced inflammatory lung injury through interacting TAK1 and activating TAK1-NFκB pathway	71
Transcription factor EB-mediated mesenchymal stem cell therapy induces autophagy and alleviates spinocerebellar ataxia type 3 defects in neuronal cells model	70
CD146 regulates the stemness and chemoresistance of hepatocellular carcinoma via JAG2-NOTCH signaling	70
METTL3-mediated m6A modification of LINC00839 maintains glioma stem cells and radiation resistance by activating Wnt/β-catenin signaling	70
Opposing roles for GSK3β and ERK1-dependent phosphorylation of huntingtin during neuronal dysfunction and cell death in Huntington’s disease	69
MIR22HG inhibits breast cancer progression by stabilizing LATS2 tumor suppressor	69
Correction to: Tumor-associated macrophage-derived exosomes transmitting miR-193a-5p promote the progression of renal cell carcinoma via TIMP2-dependent vasculogenic mimicry	68
Nitroglycerin: a comprehensive review in cancer therapy	68
Inhibitory role of proguanil on the growth of bladder cancer via enhancing EGFR degradation and inhibiting its downstream signaling pathway to induce autophagy	68
Genome-wide identification of microRNA targets reveals positive regulation of the Hippo pathway by miR-122 during liver development	67
Downregulation of TPX2 impairs the antitumor activity of CD8+ T cells in hepatocellular carcinoma	66
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer	66
High dose androgen suppresses natural killer cytotoxicity of castration-resistant prostate cancer cells via altering AR/circFKBP5/miRNA-513a-5p/PD-L1 signals	65
Glycolysis-related lncRNA TMEM105 upregulates LDHA to facilitate breast cancer liver metastasis via sponging miR-1208	65
A novel function of STAT3β in suppressing interferon response improves outcome in acute myeloid leukemia	64
Nerve growth factor promotes lysyl oxidase-dependent chondrosarcoma cell metastasis by suppressing miR-149-5p synthesis	64
Selective degradation of AR-V7 to overcome castration resistance of prostate cancer	64
Deficiency of PPP6C protects TNF-induced necroptosis through activation of TAK1	64
MiR-122-5p regulates the mevalonate pathway by targeting p53 in non-small cell lung cancer	64
Stanniocalcin 1 promotes lung metastasis of breast cancer by enhancing EGFR–ERK–S100A4 signaling	63
S1PR3-driven positive feedback loop sustains STAT3 activation and keratinocyte hyperproliferation in psoriasis	63
SMOC2 promotes an epithelial-mesenchymal transition and a pro-metastatic phenotype in epithelial cells of renal cell carcinoma origin	63
MicroRNA miR-1275 coordinately regulates AEA/LPA signals via targeting FAAH in lipid metabolism reprogramming of gastric cancer	63
MLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL10	62
Correction: MicroRNA-29a induces loss of 5-hydroxymethylcytosine and promotes metastasis of hepatocellular carcinoma through a TET–SOCS1–MMP9 signaling axis	62
DDX5 deficiency drives non-canonical NF-κB activation and NRF2 expression, influencing sorafenib response and hepatocellular carcinoma progression	62
Tim-3+ decidual Mφs induced Th2 and Treg bias in decidual CD4+T cells and promoted pregnancy maintenance via CD132	62
Germline specific genes increase DNA double-strand break repair and radioresistance in lung adenocarcinoma cells	61
Correction: FANCI plays an essential role in spermatogenesis and regulates meiotic histone methylation	61
Reduced protection of RIPK3-deficient mice against influenza by matrix protein 2 ectodomain targeted active and passive vaccination strategies	61
TAB182 aggravates progression of esophageal squamous cell carcinoma by enhancing β-catenin nuclear translocation through FHL2 dependent manner	61
Retraction Note: Long noncoding RNA LINC01234 promotes serine hydroxymethyltransferase 2 expression and proliferation by competitively binding miR-642a-5p in colon cancer	60
Retraction Note: Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer	60
MLK4 regulates DNA damage response and promotes triple-negative breast cancer chemoresistance	60
Role of cardiolipins, mitochondria, and autophagy in the differentiation process activated by all-trans retinoic acid in acute promyelocytic leukemia	59
Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss	59
Balancing the functions of DNA extracellular traps in intracellular parasite infections: implications for host defense, disease pathology and therapy	59
Wet-dry-wet drug screen leads to the synthesis of TS1, a novel compound reversing lung fibrosis through inhibition of myofibroblast differentiation	59
Angiotensin II related glial cell activation and necroptosis of retinal ganglion cells after systemic hypotension in glaucoma	58
Loss of RNF41 promotes bladder cancer metastasis through increasing NUDC stability to enhance tubulin polymerization	58
SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice	58
Novel roles of luteinizing hormone (LH) in tissue regeneration-associated functions in endometrial stem cells	58
Repurposing MDM2 inhibitor RG7388 for TP53-mutant NSCLC: a p53-independent pyroptotic mechanism via ROS/p-p38/NOXA/caspase-3/GSDME axis	58

Card9 protects sepsis by regulating Ripk2-mediated activation of NLRP3 inflammasome in macrophages	58
Correction to: Deubiquitylase OTUD6B stabilizes the mutated pVHL and suppresses cell migration in clear cell renal cell carcinoma	58
Transglutaminase 2 associated with PI3K and PTEN in a membrane-bound signalosome platform blunts cell death	58
FANCI plays an essential role in spermatogenesis and regulates meiotic histone methylation	58
YAP1 facilitates the pathogenesis of psoriasis via modulating keratinocyte proliferation and inflammation	58
Ascitic fluid shear stress in concert with hepatocyte growth factor drive stemness and chemoresistance of ovarian cancer cells via the c-Met-PI3K/Akt-miR-199a-3p signaling pathway	57
Tumor-associated macrophage-derived exosomes transmitting miR-193a-5p promote the progression of renal cell carcinoma via TIMP2-dependent vasculogenic mimicry	57
Nek2A prevents centrosome clustering and induces cell death in cancer cells via KIF2C interaction	57
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway	57
NAT10 mediates TLR2 to promote podocyte senescence in adriamycin-induced nephropathy	57
Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2 recruitment onto mitochondria and PARK2-PARK6 activity during mitophagy	57
USP14/S100A11 axis promote colorectal cancer progression by inhibiting cell senescence	57
p21-activated kinase 4 controls the aggregation of α-synuclein by reducing the monomeric and aggregated forms of α-synuclein: involvement of the E3 ubiquitin ligase NEDD4-1	56
Downregulated liver-elevated long intergenic noncoding RNA (LINC02428) is a tumor suppressor that blocks KDM5B/IGF2BP1 positive feedback loop in hepatocellular carcinoma	56
Retraction Note to: Expansion of monocytic myeloid-derived suppressor cells ameliorated intestinal inflammatory response by radiation through SOCS3 expression	56
The role of vitamin K and its antagonist in the process of ferroptosis-damaged RPE-mediated CNV	56
Nuclear pore protein POM121 regulates subcellular localization and transcriptional activity of PPARγ	55
Aldolase B-driven lactagenesis and CEACAM6 activation promote cell renewal and chemoresistance in colorectal cancer through the Warburg effect	55
LncRNA FIRRE functions as a tumor promoter by interaction with PTBP1 to stabilize BECN1 mRNA and facilitate autophagy	55
TRIM26 deficiency enhancing liver regeneration through macrophage polarization and β-catenin pathway activation	55
The mitochondrial ATP-dependent potassium channel (mitoKATP) controls skeletal muscle structure and function	54
Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis	54
Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans	54
Systemic mechanisms of necrotic cell debris clearance	54
RIPK3 promoter hypermethylation in hepatocytes protects from bile acid-induced inflammation and necroptosis	54
A positive feedback loop of lncRNA-RMRP/ZNRF3 axis and Wnt/β-catenin signaling regulates the progression and temozolomide resistance in glioma	54
Androgen-targeted hsa_circ_0085121 encodes a novel protein and improves the development of prostate cancer through facilitating the activity of PI3K/Akt/mTOR pathway and enhancing AR-V7 alternative sp	54
Exosomes derived from mesenchymal stem cells in diabetes and diabetic complications	53
SAP130 released by damaged tubule drives necroinflammation via miRNA-219c/Mincle signaling in acute kidney injury	53
Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer’s disease	53
β‐arrestin 2 negatively regulates lung cancer progression by inhibiting the TRAF6 signaling axis for NF-κB activation and autophagy induced by TLR3 and TLR4	53
O-GlcNAcylation inhibition redirects the response of colon cancer cells to chemotherapy from senescence to apoptosis	53
Innate and adaptive immune cell interaction drives inflammasome activation and hepatocyte apoptosis in murine liver injury from immune checkpoint inhibitors	52
TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC4	52
Galectin-3 promotes secretion of proteases that decrease epithelium integrity in human colon cancer cells	52
STING dependent BAX-IRF3 signaling results in apoptosis during late-stage Coxiella burnetii infection	52
LncRNA SNHG1 regulates neuroblastoma cell fate via interactions with HDAC1/2	52
Metabolic gatekeepers: harnessing tumor-derived metabolites to optimize T cell-based immunotherapy efficacy in the tumor microenvironment	52
Circulating miR-184 is a potential predictive biomarker of cardiac damage in Anderson–Fabry disease	52
Therapeutic targeting of both dihydroorotate dehydrogenase and nucleoside transport in MYCN-amplified neuroblastoma	51
Critical analysis of translational potential of rodent models of white matter pathology across a wide spectrum of human diseases	51
Chemotoxicity-induced exosomal lncFERO regulates ferroptosis and stemness in gastric cancer stem cells	51
PRMT1-mediated methylation of UBE2m promoting calcium oxalate crystal-induced kidney injury by inhibiting fatty acid metabolism	51
Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia	51
Alpha-Synuclein defects autophagy by impairing SNAP29-mediated autophagosome-lysosome fusion	51
Exosomal circTGFBR2 promotes hepatocellular carcinoma progression via enhancing ATG5 mediated protective autophagy	51
GSDMD-dependent neutrophil extracellular traps promote macrophage-to-myofibroblast transition and renal fibrosis in obstructive nephropathy	51
SUMOylation of PDPK1 Is required to maintain glycolysis-dependent CD4 T-cell homeostasis	51
Protein kinase G inhibition preserves photoreceptor viability and function in a new mouse model for autosomal dominant retinitis pigmentosa	51
TNFAIP2 promotes HIF1α transcription and breast cancer angiogenesis by activating the Rac1-ERK-AP1 signaling axis	51
BNIP3 (BCL2 interacting protein 3) regulates pluripotency by modulating mitochondrial homeostasis via mitophagy	51
Hepatocyte DDX3X protects against drug-induced acute liver injury via controlling stress granule formation and oxidative stress	50
The feedback loop between MTA1 and MTA3/TRIM21 modulates stemness of breast cancer in response to estrogen	50
A novel Hoxd13 mutation causes synpolydactyly and promotes osteoclast differentiation by regulating pSmad5/p65/c-Fos/Rank axis	50
CircNEIL3 mediates pyroptosis to influence lung adenocarcinoma radiotherapy by upregulating PIF1 through miR-1184 inhibition	50
Trim21-mediated CCT2 ubiquitination suppresses malignant progression and promotes CD4+T cell activation in breast cancer	50
TGF-β-induced PLEK2 promotes metastasis and chemoresistance in oesophageal squamous cell carcinoma by regulating LCN2	50
Histone methyltransferase Smyd2 drives adipogenesis via regulating STAT3 phosphorylation	50
The kinase activity of integrin-linked kinase regulates cellular senescence in gastric cancer	50
Transcriptome reprogramming of Epstein-Barr virus infected epithelial and B cells reveals distinct host-virus interaction profiles	50
Novel FABP4+C1q+ macrophages enhance antitumor immunity and associated with response to neoadjuvant pembrolizumab and chemotherapy in NSCLC via AMPK/JAK/STAT axis	49
PAK6 rescues pathogenic LRRK2-mediated ciliogenesis and centrosomal cohesion defects in a mutation-specific manner	49
Targeting metabolic vulnerability by combining NAMPT inhibitors and disulfiram for treatment of recurrent ovarian cancer	49
TNFAIP8 protein functions as a tumor suppressor in inflammation-associated colorectal tumorigenesis	49
Generation of functional neurons from adult human mucosal olfactory ensheathing glia by direct lineage conversion	49
Correction: SETD8 inhibits apoptosis and ferroptosis of Ewing’s sarcoma through YBX1/RAC3 axis	49
The potential impact of RNA splicing abnormalities on immune regulation in endometrial cancer	49
Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer	49
The CRTC-CREB axis functions as a transcriptional sensor to protect against proteotoxic stress in Drosophila	49
Neddylation-mediated degradation of hnRNPA2B1 contributes to hypertriglyceridemia pancreatitis	48
Targeting tumor suppressor p53 for organ fibrosis therapy	48
Retraction Note: Identification of protein kinase inhibitors to reprogram breast cancer cells	48
CPAP enhances and maintains chronic inflammation in hepatocytes to promote hepatocarcinogenesis	48
Exosomal circRNA BTG2 derived from RBP-J overexpressed-macrophages inhibits glioma progression via miR-25-3p/PTEN	48
NINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosis	48
Advances in research on immunocyte iron metabolism, ferroptosis, and their regulatory roles in autoimmune and autoinflammatory diseases	48
Correction to: ONECUT2 facilitates hepatocellular carcinoma metastasis by transcriptionally upregulating FGF2 and ACLY	48
Selective deletion of E3 ubiquitin ligase FBW7 in VE-cadherin-positive cells instigates diffuse large B-cell lymphoma in mice in vivo	48
The deubiquitinating enzyme OTUD7b protects dendritic cells from TNF-induced apoptosis by stabilizing the E3 ligase TRAF2	48
The duality of CXCR3 in glioblastoma: unveiling autocrine and paracrine mechanisms for novel therapeutic approaches	48
Tumor-suppressive function of EZH2 is through inhibiting glutaminase	48
Correction to: Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells	48
Amino acid deprivation induces AKT activation by inducing GCN2/ATF4/REDD1 axis	48
Hydroxyurea blunts mitochondrial energy metabolism and osteoblast and osteoclast differentiation exacerbating trabecular bone loss in sickle cell mice	47
Correction: Tumor-educated B cells promote renal cancer metastasis via inducing the IL-1β/HIF-2α/Notch1 signals	47
Retraction Note: RUNX3-regulated circRNA METTL3 inhibits colorectal cancer proliferation and metastasis via miR-107/PER3 axis	47
Inhibition of the immunoproteasome modulates innate immunity to ameliorate muscle pathology of dysferlin-deficient BlAJ mice	47
Retraction Note: Involvement of autophagy in hypoxia-BNIP3 signaling to promote epidermal keratinocyte migration	47
Role of reactive oxygen species in regulating 27-hydroxycholesterol-induced apoptosis of hematopoietic progenitor cells and myeloid cell lines	47
Mechanistic insights into SIRT7 and EZH2 regulation of cisplatin resistance in bladder cancer cells	47
Circ_0057558 promotes nonalcoholic fatty liver disease by regulating ROCK1/AMPK signaling through targeting miR-206	47
AURKAIP1 actuates tumor progression through stabilizing DDX5 in triple negative breast cancer	46
Combination of tyrosine kinase inhibitors and the MCL1 inhibitor S63845 exerts synergistic antitumorigenic effects on CML cells	46
Deficiency of SIAH1 promotes the formation of filopodia by increasing the accumulation of FASN in liver cancer	46
The oleic/palmitic acid imbalance in exosomes isolated from NAFLD patients induces necroptosis of liver cells via the elongase-6/RIP-1 pathway	46