Cell Death & Disease

Papers
(The median citation count of Cell Death & Disease is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)
ArticleCitations
Adding pieces to the puzzle of differentiated-to-anaplastic thyroid cancer evolution: the oncogene E2F7373
Correction: TRPM8 contributes to liver regeneration via mitochondrial energy metabolism mediated by PGC1α345
The Janus face of endogenous neuronal tPA: promoting self-protection and worsening the death of neighboring neurons337
FOXA1 prevents nutrients deprivation induced autophagic cell death through inducing loss of imprinting of IGF2 in lung adenocarcinoma318
Genetic alterations of Keap1 confers chemotherapeutic resistance through functional activation of Nrf2 and Notch pathway in head and neck squamous cell carcinoma316
Elaiophylin reduces body weight and lowers glucose levels in obese mice by activating AMPK231
Dominant-negative p53-overexpression in skeletal muscle induces cell death and fiber atrophy in rats219
IL-17A injury to retinal ganglion cells is mediated by retinal Müller cells in diabetic retinopathy216
Correction: NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation210
Correction: Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells201
Correction: Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis176
Distinct functions of wild-type and R273H mutant Δ133p53α differentially regulate glioblastoma aggressiveness and therapy-induced senescence175
Correction: Adipose-derived mesenchymal stromal cells promote corneal wound healing by accelerating the clearance of neutrophils in cornea171
Tripartite motif 25 ameliorates doxorubicin-induced cardiotoxicity by degrading p85α171
Single-cell RNA-seq and pathological phenotype reveal the functional atlas and precise roles of Sox30 in testicular cell development and differentiation160
Differential kinetics of splenic CD169+ macrophage death is one underlying cause of virus infection fate regulation159
ZBTB7B is a permissive regulator of hepatocellular carcinoma initiation by repressing c-Jun expression and function154
GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila153
p63, a key regulator of Ago2, links to the microRNA-144 cluster146
p53-loss induced prostatic epithelial cell plasticity and invasion is driven by a crosstalk with the tumor microenvironment146
Defective hematopoietic differentiation of immune aplastic anemia patient-derived iPSCs146
Preservation of retinal structure and function in two mouse models of inherited retinal degeneration by ONL1204, an inhibitor of the Fas receptor145
A novel protein encoded by circUBE4B promotes progression of esophageal squamous cell carcinoma by augmenting MAPK/ERK signaling143
IGFBP2/ITGA5 promotes gefitinib resistance via activating STAT3/CXCL1 axis in non-small cell lung cancer140
ER-mitochondria association negatively affects wound healing by regulating NLRP3 activation139
Underlying mechanisms of glucocorticoid-induced β-cell death and dysfunction: a new role for glycogen synthase kinase 3139
GBA1-dependent membrane glucosylceramide reprogramming promotes liver cancer metastasis via activation of the Wnt/β-catenin signalling pathway139
UPF1 contributes to the maintenance of endometrial cancer stem cell phenotype by stabilizing LINC00963136
USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma135
Pharmacological inhibition of Ref-1 enhances the therapeutic sensitivity of papillary thyroid carcinoma to vemurafenib132
NADH:ubiquinone oxidoreductase core subunit S8 expression and functional significance in non-small cell lung cancer131
MESH1 knockdown triggers proliferation arrest through TAZ repression131
JUND/linc00976 promotes cholangiocarcinoma progression and metastasis, inhibits ferroptosis by regulating the miR-3202/GPX4 axis129
LINC00152 induced by TGF-β promotes metastasis via HuR in lung adenocarcinoma129
Apatinib inhibits glioma cell malignancy in patient-derived orthotopic xenograft mouse model by targeting thrombospondin 1/myosin heavy chain 9 axis129
Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibition127
The multifaceted role of Fragile X-Related Protein 1 (FXR1) in cellular processes: an updated review on cancer and clinical applications126
Tulp1 deficiency causes early-onset retinal degeneration through affecting ciliogenesis and activating ferroptosis in zebrafish121
TRAIL protects the immature lung from hyperoxic injury120
MicroRNA miR-20a-5p targets CYCS to inhibit apoptosis in hepatocellular carcinoma119
RNA helicase DDX5 modulates sorafenib sensitivity in hepatocellular carcinoma via the Wnt/β-catenin–ferroptosis axis119
MAGI3 enhances sensitivity to sunitinib in renal cell carcinoma by suppressing the MAS/ERK axis and serves as a prognostic marker119
FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression117
Therapeutic efficacy of TMTP1-modified EVs in overcoming bone metastasis and immune resistance in PIK3CA mutant NSCLC115
Mitochondria-derived H2O2 triggers liver regeneration via FoxO3a signaling pathway after partial hepatectomy in mice114
Long noncoding RNA LINC01594 inhibits the CELF6-mediated splicing of oncogenic CD44 variants to promote colorectal cancer metastasis113
Functional delivery of lncRNA TUG1 by endothelial progenitor cells derived extracellular vesicles confers anti-inflammatory macrophage polarization in sepsis via impairing miR-9-5p-targeted SIRT1 inhi111
Overexpression of EphB6 and EphrinB2 controls soma spacing of cortical neurons in a mutual inhibitory way110
Migration deficits of the neural crest caused by CXADR triplication in a human Down syndrome stem cell model108
The role of SPATA2 in TNF signaling, cancer, and spermatogenesis107
NEDD4L binds the proteasome and promotes autophagy and bortezomib sensitivity in multiple myeloma106
Enhancing cell death in B-cell malignancies through targeted inhibition of Bcl-3105
Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma105
A novel inhibitor of the mitochondrial respiratory complex I with uncoupling properties exerts potent antitumor activity104
PRMT1 methylation of WTAP promotes multiple myeloma tumorigenesis by activating oxidative phosphorylation via m6A modification of NDUFS6103
Endothelial ETS1 inhibition exacerbate blood–brain barrier dysfunction in multiple sclerosis through inducing endothelial-to-mesenchymal transition101
Nuclear factor I-C disrupts cellular homeostasis between autophagy and apoptosis via miR-200b-Ambra1 in neural tube defects100
DNAJA4 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma via PSMD2-mediated MYH9 degradation99
ATF4/CEMIP/PKCα promotes anoikis resistance by enhancing protective autophagy in prostate cancer cells99
The intrinsic role and mechanism of tumor expressed-CD38 on lung adenocarcinoma progression99
PD-L1 induces autophagy and primary resistance to EGFR–TKIs in EGFR-mutant lung adenocarcinoma via the MAPK signaling pathway98
CD36 aggravates podocyte injury by activating NLRP3 inflammasome and inhibiting autophagy in lupus nephritis98
Pivotal role of IL-8 derived from the interaction between osteosarcoma and tumor-associated macrophages in osteosarcoma growth and metastasis via the FAK pathway97
SerpinB7 deficiency contributes to development of psoriasis via calcium-mediated keratinocyte differentiation dysfunction94
METTL16 controls Kaposi’s sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle93
Ferroptotic MSCs protect mice against sepsis via promoting macrophage efferocytosis93
CAR-T therapy dilemma and innovative design strategies for next generation93
m6A and m5C modification of GPX4 facilitates anticancer immunity via STING activation92
Lysine methyltransferase SMYD2 inhibits antiviral innate immunity by promoting IRF3 dephosphorylation91
BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma91
miR-28-based combination therapy impairs aggressive B cell lymphoma growth by rewiring DNA replication89
Knockdown of Porf-2 restores visual function after optic nerve crush injury89
BRISC is required for optimal activation of NF-κB in Kupffer cells induced by LPS and contributes to acute liver injury88
m5C-dependent cross-regulation between nuclear reader ALYREF and writer NSUN2 promotes urothelial bladder cancer malignancy through facilitating RABL6/TK1 mRNAs splicing and stabilization87
CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT386
GPX4 and vitamin E cooperatively protect hematopoietic stem and progenitor cells from lipid peroxidation and ferroptosis86
CYP1B1 inhibits ferroptosis and induces anti-PD-1 resistance by degrading ACSL4 in colorectal cancer86
Therapeutic role of PTEN in tissue regeneration for management of neurological disorders: stem cell behaviors to an in-depth review85
Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop84
PPFIBP1 induces glioma cell migration and invasion through FAK/Src/JNK signaling pathway84
LAPTM4B-mediated hepatocellular carcinoma stem cell proliferation and MDSC migration: implications for HCC progression and sensitivity to PD-L1 monoclonal antibody therapy83
Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG183
Identification of multiple organ metastasis-associated hub mRNA/miRNA signatures in non-small cell lung cancer83
FTO/IGF2BP2-mediated N6 methyladenosine modification in invasion and metastasis of thyroid carcinoma via CDH1282
Leveraging glycosylation for early detection and therapeutic target discovery in pancreatic cancer82
KDM1A epigenetically enhances RAD51 expression to suppress the STING-associated anti-tumor immunity in esophageal squamous cell carcinoma82
In vivo self-assembly and delivery of VEGFR2 siRNA-encapsulated small extracellular vesicles for lung metastatic osteosarcoma therapy81
Single-cell sequencing resolves the landscape of immune cells and regulatory mechanisms in HIV-infected immune non-responders81
RNF115/BCA2 deficiency alleviated acute liver injury in mice by promoting autophagy and inhibiting inflammatory response81
RNAi-based ALOX15B silencing augments keratinocyte inflammation in vitro via EGFR/STAT1/JAK1 signalling80
Zipper-interacting protein kinase mediates neuronal cell death and cognitive dysfunction in traumatic brain injury via regulating DEDD80
PRMT1-mediated EZH2 methylation promotes breast cancer cell proliferation and tumorigenesis78
Glucose deprivation triggers DCAF1-mediated inactivation of Rheb-mTORC1 and promotes cancer cell survival77
SOX4-BMI1 axis promotes non-small cell lung cancer progression and facilitates angiogenesis by suppressing ZNF2476
PAF1 cooperates with YAP1 in metaplastic ducts to promote pancreatic cancer76
TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway75
Radiotherapy remodels the tumor microenvironment for enhancing immunotherapeutic sensitivity75
Aryl hydrocarbon receptor dependent anti-inflammation and neuroprotective effects of tryptophan metabolites on retinal ischemia/reperfusion injury75
A carbazole compound, 9-ethyl-9H-carbazole-3-carbaldehyde, plays an antitumor function through reactivation of the p53 pathway in human melanoma cells75
FAK mediates LPS-induced inflammatory lung injury through interacting TAK1 and activating TAK1-NFκB pathway75
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation75
Mitochondrial Drp1 recognizes and induces excessive mPTP opening after hypoxia through BAX-PiC and LRRK2-HK274
Hypoxia-responsive circRNAs: A novel but important participant in non-coding RNAs ushered toward tumor hypoxia73
Regulatory T cells in skeletal muscle repair and regeneration: recent insights73
The tyrosine-kinase inhibitor Nintedanib ameliorates autosomal-dominant polycystic kidney disease73
An integrated bioinformatic investigation of mitochondrial solute carrier family 25 (SLC25) in colon cancer followed by preliminary validation of member 5 (SLC25A5) in tumorigenesis72
METTL3-mediated m6A modification of LINC00839 maintains glioma stem cells and radiation resistance by activating Wnt/β-catenin signaling72
USP1 modulates hepatocellular carcinoma progression via the Hippo/TAZ axis72
The regulation, function, and role of lipophagy, a form of selective autophagy, in metabolic disorders72
KLF13 promotes esophageal cancer progression and regulates triacylglyceride and free fatty acid metabolism through GPIHBP171
USP11-mediated LSH deubiquitination inhibits ferroptosis in colorectal cancer through epigenetic activation of CYP24A171
Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation70
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC70
Marizomib sensitizes primary glioma cells to apoptosis induced by a latest-generation TRAIL receptor agonist69
CD146 regulates the stemness and chemoresistance of hepatocellular carcinoma via JAG2-NOTCH signaling69
Transcription factor EB-mediated mesenchymal stem cell therapy induces autophagy and alleviates spinocerebellar ataxia type 3 defects in neuronal cells model68
Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia68
SUMOylation of PDPK1 Is required to maintain glycolysis-dependent CD4 T-cell homeostasis68
MIR22HG inhibits breast cancer progression by stabilizing LATS2 tumor suppressor68
Glycolysis-related lncRNA TMEM105 upregulates LDHA to facilitate breast cancer liver metastasis via sponging miR-120867
Trim21-mediated CCT2 ubiquitination suppresses malignant progression and promotes CD4+T cell activation in breast cancer67
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway67
Nitroglycerin: a comprehensive review in cancer therapy66
Opposing roles for GSK3β and ERK1-dependent phosphorylation of huntingtin during neuronal dysfunction and cell death in Huntington’s disease66
Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans66
Inhibitory role of proguanil on the growth of bladder cancer via enhancing EGFR degradation and inhibiting its downstream signaling pathway to induce autophagy66
Circulating miR-184 is a potential predictive biomarker of cardiac damage in Anderson–Fabry disease65
SAP130 released by damaged tubule drives necroinflammation via miRNA-219c/Mincle signaling in acute kidney injury65
O-GlcNAcylation inhibition redirects the response of colon cancer cells to chemotherapy from senescence to apoptosis64
Androgen-targeted hsa_circ_0085121 encodes a novel protein and improves the development of prostate cancer through facilitating the activity of PI3K/Akt/mTOR pathway and enhancing AR-V7 alternative sp64
Correction to: Tumor-associated macrophage-derived exosomes transmitting miR-193a-5p promote the progression of renal cell carcinoma via TIMP2-dependent vasculogenic mimicry64
Correction: MicroRNA-29a induces loss of 5-hydroxymethylcytosine and promotes metastasis of hepatocellular carcinoma through a TET–SOCS1–MMP9 signaling axis63
Nerve growth factor promotes lysyl oxidase-dependent chondrosarcoma cell metastasis by suppressing miR-149-5p synthesis63
TAB182 aggravates progression of esophageal squamous cell carcinoma by enhancing β-catenin nuclear translocation through FHL2 dependent manner63
Genome-wide identification of microRNA targets reveals positive regulation of the Hippo pathway by miR-122 during liver development63
An integrative transcriptome study reveals Ddit4/Redd1 as a key regulator of cancer cachexia in rodent models63
Nuclear pore protein POM121 regulates subcellular localization and transcriptional activity of PPARγ62
Reduced protection of RIPK3-deficient mice against influenza by matrix protein 2 ectodomain targeted active and passive vaccination strategies62
Germline specific genes increase DNA double-strand break repair and radioresistance in lung adenocarcinoma cells62
Correction: FANCI plays an essential role in spermatogenesis and regulates meiotic histone methylation62
MLK4 regulates DNA damage response and promotes triple-negative breast cancer chemoresistance61
Retraction Note: Dual roles of miR-374a by modulated c-Jun respectively targets CCND1-inducing PI3K/AKT signal and PTEN-suppressing Wnt/β-catenin signaling in non-small-cell lung cancer61
Retraction Note: Long noncoding RNA LINC01234 promotes serine hydroxymethyltransferase 2 expression and proliferation by competitively binding miR-642a-5p in colon cancer61
Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss61
Retraction Note: Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer61
Histone methyltransferase Smyd2 drives adipogenesis via regulating STAT3 phosphorylation60
Wet-dry-wet drug screen leads to the synthesis of TS1, a novel compound reversing lung fibrosis through inhibition of myofibroblast differentiation60
Role of cardiolipins, mitochondria, and autophagy in the differentiation process activated by all-trans retinoic acid in acute promyelocytic leukemia60
TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC460
S1PR3-driven positive feedback loop sustains STAT3 activation and keratinocyte hyperproliferation in psoriasis59
Balancing the functions of DNA extracellular traps in intracellular parasite infections: implications for host defense, disease pathology and therapy59
p21-activated kinase 4 controls the aggregation of α-synuclein by reducing the monomeric and aggregated forms of α-synuclein: involvement of the E3 ubiquitin ligase NEDD4-159
Selective degradation of AR-V7 to overcome castration resistance of prostate cancer59
The feedback loop between MTA1 and MTA3/TRIM21 modulates stemness of breast cancer in response to estrogen58
Novel roles of luteinizing hormone (LH) in tissue regeneration-associated functions in endometrial stem cells58
A novel Hoxd13 mutation causes synpolydactyly and promotes osteoclast differentiation by regulating pSmad5/p65/c-Fos/Rank axis58
SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice57
The role of vitamin K and its antagonist in the process of ferroptosis-damaged RPE-mediated CNV57
RIPK3 promoter hypermethylation in hepatocytes protects from bile acid-induced inflammation and necroptosis57
BH3-only protein expression determines hepatocellular carcinoma response to sorafenib-based treatment57
YAP1 facilitates the pathogenesis of psoriasis via modulating keratinocyte proliferation and inflammation57
Transglutaminase 2 associated with PI3K and PTEN in a membrane-bound signalosome platform blunts cell death57
Correction to: Deubiquitylase OTUD6B stabilizes the mutated pVHL and suppresses cell migration in clear cell renal cell carcinoma57
FANCI plays an essential role in spermatogenesis and regulates meiotic histone methylation56
Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2 recruitment onto mitochondria and PARK2-PARK6 activity during mitophagy56
The kinase activity of integrin-linked kinase regulates cellular senescence in gastric cancer56
Innate and adaptive immune cell interaction drives inflammasome activation and hepatocyte apoptosis in murine liver injury from immune checkpoint inhibitors56
Alpha-Synuclein defects autophagy by impairing SNAP29-mediated autophagosome-lysosome fusion56
NAT10 mediates TLR2 to promote podocyte senescence in adriamycin-induced nephropathy56
Card9 protects sepsis by regulating Ripk2-mediated activation of NLRP3 inflammasome in macrophages56
USP14/S100A11 axis promote colorectal cancer progression by inhibiting cell senescence55
Chemotoxicity-induced exosomal lncFERO regulates ferroptosis and stemness in gastric cancer stem cells55
Deficiency of PPP6C protects TNF-induced necroptosis through activation of TAK155
Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer’s disease55
High dose androgen suppresses natural killer cytotoxicity of castration-resistant prostate cancer cells via altering AR/circFKBP5/miRNA-513a-5p/PD-L1 signals54
DHA exhibits synergistic therapeutic efficacy with cisplatin to induce ferroptosis in pancreatic ductal adenocarcinoma via modulation of iron metabolism54
A positive feedback loop of lncRNA-RMRP/ZNRF3 axis and Wnt/β-catenin signaling regulates the progression and temozolomide resistance in glioma54
Therapeutic targeting of both dihydroorotate dehydrogenase and nucleoside transport in MYCN-amplified neuroblastoma54
Systemic mechanisms of necrotic cell debris clearance54
β‐arrestin 2 negatively regulates lung cancer progression by inhibiting the TRAF6 signaling axis for NF-κB activation and autophagy induced by TLR3 and TLR453
A novel function of STAT3β in suppressing interferon response improves outcome in acute myeloid leukemia53
MiR-122-5p regulates the mevalonate pathway by targeting p53 in non-small cell lung cancer53
Hepatocyte DDX3X protects against drug-induced acute liver injury via controlling stress granule formation and oxidative stress53
TRIM26 deficiency enhancing liver regeneration through macrophage polarization and β-catenin pathway activation53
Aldolase B-driven lactagenesis and CEACAM6 activation promote cell renewal and chemoresistance in colorectal cancer through the Warburg effect53
Retraction Note to: Expansion of monocytic myeloid-derived suppressor cells ameliorated intestinal inflammatory response by radiation through SOCS3 expression53
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer52
DDX5 deficiency drives non-canonical NF-κB activation and NRF2 expression, influencing sorafenib response and hepatocellular carcinoma progression52
LncRNA FIRRE functions as a tumor promoter by interaction with PTBP1 to stabilize BECN1 mRNA and facilitate autophagy52
MicroRNA miR-1275 coordinately regulates AEA/LPA signals via targeting FAAH in lipid metabolism reprogramming of gastric cancer52
Galectin-3 promotes secretion of proteases that decrease epithelium integrity in human colon cancer cells52
BNIP3 (BCL2 interacting protein 3) regulates pluripotency by modulating mitochondrial homeostasis via mitophagy52
Stanniocalcin 1 promotes lung metastasis of breast cancer by enhancing EGFR–ERK–S100A4 signaling52
Angiotensin II related glial cell activation and necroptosis of retinal ganglion cells after systemic hypotension in glaucoma52
Nek2A prevents centrosome clustering and induces cell death in cancer cells via KIF2C interaction52
Tumor-associated macrophage-derived exosomes transmitting miR-193a-5p promote the progression of renal cell carcinoma via TIMP2-dependent vasculogenic mimicry51
ZFP36L2 regulates myocardial ischemia/reperfusion injury and attenuates mitochondrial fusion and fission by LncRNA PVT151
MLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL1051
CircNEIL3 mediates pyroptosis to influence lung adenocarcinoma radiotherapy by upregulating PIF1 through miR-1184 inhibition51
The mitochondrial ATP-dependent potassium channel (mitoKATP) controls skeletal muscle structure and function51
Exosomal circTGFBR2 promotes hepatocellular carcinoma progression via enhancing ATG5 mediated protective autophagy51
Metabolic gatekeepers: harnessing tumor-derived metabolites to optimize T cell-based immunotherapy efficacy in the tumor microenvironment51
Ascitic fluid shear stress in concert with hepatocyte growth factor drive stemness and chemoresistance of ovarian cancer cells via the c-Met-PI3K/Akt-miR-199a-3p signaling pathway50
Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis50
OGA is associated with deglycosylation of NONO and the KU complex during DNA damage repair50
TNFAIP2 promotes HIF1α transcription and breast cancer angiogenesis by activating the Rac1-ERK-AP1 signaling axis50
Downregulated liver-elevated long intergenic noncoding RNA (LINC02428) is a tumor suppressor that blocks KDM5B/IGF2BP1 positive feedback loop in hepatocellular carcinoma50
STING dependent BAX-IRF3 signaling results in apoptosis during late-stage Coxiella burnetii infection49
LncRNA SNHG1 regulates neuroblastoma cell fate via interactions with HDAC1/249
Exosomes derived from mesenchymal stem cells in diabetes and diabetic complications49
SMOC2 promotes an epithelial-mesenchymal transition and a pro-metastatic phenotype in epithelial cells of renal cell carcinoma origin49
Downregulation of TPX2 impairs the antitumor activity of CD8+ T cells in hepatocellular carcinoma49
Circular RNA hsa_circ_0000277 sequesters miR-4766-5p to upregulate LAMA1 and promote esophageal carcinoma progression49
Tim-3+ decidual Mφs induced Th2 and Treg bias in decidual CD4+T cells and promoted pregnancy maintenance via CD13249
CircLIFR suppresses hepatocellular carcinoma progression by sponging miR-624-5p and inactivating the GSK-3β/β-catenin signaling pathway49
GSDMD-dependent neutrophil extracellular traps promote macrophage-to-myofibroblast transition and renal fibrosis in obstructive nephropathy49
EGFL7 drives the evolution of resistance to EGFR inhibitors in lung cancer by activating NOTCH signaling48
Transcriptome reprogramming of Epstein-Barr virus infected epithelial and B cells reveals distinct host-virus interaction profiles48
The YTHDC1 reader protein recognizes and regulates the lncRNA MEG3 following its METTL3-mediated m6A methylation: a novel mechanism early during radiation-induced liver injury48
ETS-1-activated LINC01016 over-expression promotes tumor progression via suppression of RFFL-mediated DHX9 ubiquitination degradation in breast cancers48
The deubiquitinating enzyme OTUD7b protects dendritic cells from TNF-induced apoptosis by stabilizing the E3 ligase TRAF248
TGF-β-induced PLEK2 promotes metastasis and chemoresistance in oesophageal squamous cell carcinoma by regulating LCN248
Generation of functional neurons from adult human mucosal olfactory ensheathing glia by direct lineage conversion48
Cerebral endothelial cell-derived extracellular vesicles regulate microglial polarization and promote autophagy via delivery of miR-672-5p48
PTRF-IL33-ZBP1 signaling mediating macrophage necroptosis contributes to HDM-induced airway inflammation47
Correction: SETD8 inhibits apoptosis and ferroptosis of Ewing’s sarcoma through YBX1/RAC3 axis47
Neddylation-mediated degradation of hnRNPA2B1 contributes to hypertriglyceridemia pancreatitis47
Correction to: ONECUT2 facilitates hepatocellular carcinoma metastasis by transcriptionally upregulating FGF2 and ACLY47
Targeting the apoptosis pathway to treat tumours of the paediatric nervous system47
ALCAP2 inhibits lung adenocarcinoma cell proliferation, migration and invasion via the ubiquitination of β-catenin by upregulating the E3 ligase NEDD4L47
FRMD3 inhibits the growth and metastasis of breast cancer through the ubiquitination-mediated degradation of vimentin and subsequent impairment of focal adhesion47
Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor47
MiR-1246b, a novel miRNA molecule of extracellular vesicles in bronchoalveolar lavage fluid, promotes nodule growth through FGF14 in patients with lung cancer47
Correction to: Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells47
YAP-dependent Wnt5a induction in hypertrophic adipocytes restrains adiposity47
Targeting metabolic vulnerability by combining NAMPT inhibitors and disulfiram for treatment of recurrent ovarian cancer47
CAF-derived exosomal WEE2-AS1 facilitates colorectal cancer progression via promoting degradation of MOB1A to inhibit the Hippo pathway47
Retraction Note: Identification of protein kinase inhibitors to reprogram breast cancer cells47
Tumor-suppressive function of EZH2 is through inhibiting glutaminase47
Mechanistic insights into SIRT7 and EZH2 regulation of cisplatin resistance in bladder cancer cells46
Inhibition of the immunoproteasome modulates innate immunity to ameliorate muscle pathology of dysferlin-deficient BlAJ mice46
In vivo restoration of dystrophin expression in mdx mice using intra-muscular and intra-arterial injections of hydrogel microsphere carriers of exon skipping antisense oligonucleotides46
Hydroxyurea blunts mitochondrial energy metabolism and osteoblast and osteoclast differentiation exacerbating trabecular bone loss in sickle cell mice46
Bone marrow-independent adventitial macrophage progenitor cells contribute to angiogenesis46
PAK6 rescues pathogenic LRRK2-mediated ciliogenesis and centrosomal cohesion defects in a mutation-specific manner46
Role of reactive oxygen species in regulating 27-hydroxycholesterol-induced apoptosis of hematopoietic progenitor cells and myeloid cell lines46
Retraction Note: RUNX3-regulated circRNA METTL3 inhibits colorectal cancer proliferation and metastasis via miR-107/PER3 axis46
CPAP enhances and maintains chronic inflammation in hepatocytes to promote hepatocarcinogenesis46
Selective deletion of E3 ubiquitin ligase FBW7 in VE-cadherin-positive cells instigates diffuse large B-cell lymphoma in mice in vivo46
Claudin-7 is essential for the maintenance of colonic stem cell homoeostasis via the modulation of Wnt/Notch signalling45
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