Cell Death & Disease

Article	Citations
Correction: NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation	550
PAF1 cooperates with YAP1 in metaplastic ducts to promote pancreatic cancer	434
Differential kinetics of splenic CD169+ macrophage death is one underlying cause of virus infection fate regulation	433
GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila	409
Correction: Adipose-derived mesenchymal stromal cells promote corneal wound healing by accelerating the clearance of neutrophils in cornea	386
Correction: Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells	296
Correction: Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis	293
Adding pieces to the puzzle of differentiated-to-anaplastic thyroid cancer evolution: the oncogene E2F7	268
Correction: TRPM8 contributes to liver regeneration via mitochondrial energy metabolism mediated by PGC1α	247
The Janus face of endogenous neuronal tPA: promoting self-protection and worsening the death of neighboring neurons	235
FOXA1 prevents nutrients deprivation induced autophagic cell death through inducing loss of imprinting of IGF2 in lung adenocarcinoma	224
Dominant-negative p53-overexpression in skeletal muscle induces cell death and fiber atrophy in rats	223
ZBTB7B is a permissive regulator of hepatocellular carcinoma initiation by repressing c-Jun expression and function	207
Therapeutic efficacy of TMTP1-modified EVs in overcoming bone metastasis and immune resistance in PIK3CA mutant NSCLC	207
Ferroptotic MSCs protect mice against sepsis via promoting macrophage efferocytosis	202
Elaiophylin reduces body weight and lowers glucose levels in obese mice by activating AMPK	194
UPF1 contributes to the maintenance of endometrial cancer stem cell phenotype by stabilizing LINC00963	191
Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation	185
Endothelial ETS1 inhibition exacerbate blood–brain barrier dysfunction in multiple sclerosis through inducing endothelial-to-mesenchymal transition	182
RNAi-based ALOX15B silencing augments keratinocyte inflammation in vitro via EGFR/STAT1/JAK1 signalling	182
RNA helicase DDX5 modulates sorafenib sensitivity in hepatocellular carcinoma via the Wnt/β-catenin–ferroptosis axis	179
KDM1A epigenetically enhances RAD51 expression to suppress the STING-associated anti-tumor immunity in esophageal squamous cell carcinoma	178
miR-28-based combination therapy impairs aggressive B cell lymphoma growth by rewiring DNA replication	169
Overexpression of EphB6 and EphrinB2 controls soma spacing of cortical neurons in a mutual inhibitory way	169
Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma	161

Single-cell sequencing resolves the landscape of immune cells and regulatory mechanisms in HIV-infected immune non-responders	158
Targeting FAM111B attenuates mitophagy and increases the sensitivity to lenvatinib treatment by increasing MFN2 stability in hepatocellular carcinoma	157
CircPSD3 aggravates tumor progression by maintaining TCA cycle and mitochondrial function via regulating SUCLG2 in thyroid carcinoma	156
ZC3H13 mediates N6-methyladenosine modification of SNTB1 to promote epithelial-mesenchymal transition in gastric cancer	151
ATRA upregulates OTUD6B to recruit CD8+ T cells to suppress colorectal liver metastasis by stabilizing DDX5/STAT3/CXCL11 axis	150
Phosphorylation of USP33 by CDK1 stabilizes the mTORC2 component SIN1	146
Pharmacological inhibition of Ref-1 enhances the therapeutic sensitivity of papillary thyroid carcinoma to vemurafenib	145
Multi-omics prediction of axillary treatment response and tumour microenvironment alterations in lymph node-positive luminal breast cancer	140
Macrophages downregulate NEDD9 to counteract S. Typhimurium- mediated FAK-AKT activation and lysosome inhibition	140
Mitochondria-derived H2O2 triggers liver regeneration via FoxO3a signaling pathway after partial hepatectomy in mice	140
METTL16 controls Kaposi’s sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle	139
Glucose deprivation triggers DCAF1-mediated inactivation of Rheb-mTORC1 and promotes cancer cell survival	139
Mitochondrial Drp1 recognizes and induces excessive mPTP opening after hypoxia through BAX-PiC and LRRK2-HK2	136
Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibition	136
BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma	134
MicroRNA miR-20a-5p targets CYCS to inhibit apoptosis in hepatocellular carcinoma	131
Enhancing cell death in B-cell malignancies through targeted inhibition of Bcl-3	130
Tripartite motif 25 ameliorates doxorubicin-induced cardiotoxicity by degrading p85α	128
IL-17A injury to retinal ganglion cells is mediated by retinal Müller cells in diabetic retinopathy	128
SerpinB7 deficiency contributes to development of psoriasis via calcium-mediated keratinocyte differentiation dysfunction	126
LINC00152 induced by TGF-β promotes metastasis via HuR in lung adenocarcinoma	125
JUND/linc00976 promotes cholangiocarcinoma progression and metastasis, inhibits ferroptosis by regulating the miR-3202/GPX4 axis	123
Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop	123
GBA1-dependent membrane glucosylceramide reprogramming promotes liver cancer metastasis via activation of the Wnt/β-catenin signalling pathway	121
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation	121
Apatinib inhibits glioma cell malignancy in patient-derived orthotopic xenograft mouse model by targeting thrombospondin 1/myosin heavy chain 9 axis	121
Pivotal role of IL-8 derived from the interaction between osteosarcoma and tumor-associated macrophages in osteosarcoma growth and metastasis via the FAK pathway	118
Preservation of retinal structure and function in two mouse models of inherited retinal degeneration by ONL1204, an inhibitor of the Fas receptor	118
Radiotherapy remodels the tumor microenvironment for enhancing immunotherapeutic sensitivity	115
Tulp1 deficiency causes early-onset retinal degeneration through affecting ciliogenesis and activating ferroptosis in zebrafish	114
NEDD4L binds the proteasome and promotes autophagy and bortezomib sensitivity in multiple myeloma	114
Leveraging glycosylation for early detection and therapeutic target discovery in pancreatic cancer	114
An integrated bioinformatic investigation of mitochondrial solute carrier family 25 (SLC25) in colon cancer followed by preliminary validation of member 5 (SLC25A5) in tumorigenesis	114
Hypoxia-responsive circRNAs: A novel but important participant in non-coding RNAs ushered toward tumor hypoxia	113
TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway	112
A novel protein encoded by circUBE4B promotes progression of esophageal squamous cell carcinoma by augmenting MAPK/ERK signaling	111
ATF4/CEMIP/PKCα promotes anoikis resistance by enhancing protective autophagy in prostate cancer cells	110
Functional delivery of lncRNA TUG1 by endothelial progenitor cells derived extracellular vesicles confers anti-inflammatory macrophage polarization in sepsis via impairing miR-9-5p-targeted SIRT1 inhi	108
PD-L1 induces autophagy and primary resistance to EGFR–TKIs in EGFR-mutant lung adenocarcinoma via the MAPK signaling pathway	105
METTL3-mediated m6A modification of LINC00839 maintains glioma stem cells and radiation resistance by activating Wnt/β-catenin signaling	105
MESH1 knockdown triggers proliferation arrest through TAZ repression	103
FTO/IGF2BP2-mediated N6 methyladenosine modification in invasion and metastasis of thyroid carcinoma via CDH12	102
CAR-T therapy dilemma and innovative design strategies for next generation	102
FAK mediates LPS-induced inflammatory lung injury through interacting TAK1 and activating TAK1-NFκB pathway	101
BRISC is required for optimal activation of NF-κB in Kupffer cells induced by LPS and contributes to acute liver injury	100
Nuclear factor I-C disrupts cellular homeostasis between autophagy and apoptosis via miR-200b-Ambra1 in neural tube defects	100
PRMT1-mediated EZH2 methylation promotes breast cancer cell proliferation and tumorigenesis	100
Genetic alterations of Keap1 confers chemotherapeutic resistance through functional activation of Nrf2 and Notch pathway in head and neck squamous cell carcinoma	99
Zipper-interacting protein kinase mediates neuronal cell death and cognitive dysfunction in traumatic brain injury via regulating DEDD	96
Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1	95

CYP1B1 inhibits ferroptosis and induces anti-PD-1 resistance by degrading ACSL4 in colorectal cancer	95
The multifaceted role of Fragile X-Related Protein 1 (FXR1) in cellular processes: an updated review on cancer and clinical applications	95
Aryl hydrocarbon receptor dependent anti-inflammation and neuroprotective effects of tryptophan metabolites on retinal ischemia/reperfusion injury	93
Identification of multiple organ metastasis-associated hub mRNA/miRNA signatures in non-small cell lung cancer	93
Underlying mechanisms of glucocorticoid-induced β-cell death and dysfunction: a new role for glycogen synthase kinase 3	93
Long noncoding RNA LINC01594 inhibits the CELF6-mediated splicing of oncogenic CD44 variants to promote colorectal cancer metastasis	91
DNAJA4 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma via PSMD2-mediated MYH9 degradation	90
PRMT1 methylation of WTAP promotes multiple myeloma tumorigenesis by activating oxidative phosphorylation via m6A modification of NDUFS6	90
p53-loss induced prostatic epithelial cell plasticity and invasion is driven by a crosstalk with the tumor microenvironment	90
KLF13 promotes esophageal cancer progression and regulates triacylglyceride and free fatty acid metabolism through GPIHBP1	89
LAPTM4B-mediated hepatocellular carcinoma stem cell proliferation and MDSC migration: implications for HCC progression and sensitivity to PD-L1 monoclonal antibody therapy	89
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC	88
MAGI3 enhances sensitivity to sunitinib in renal cell carcinoma by suppressing the MAS/ERK axis and serves as a prognostic marker	88
Single-cell RNA-seq and pathological phenotype reveal the functional atlas and precise roles of Sox30 in testicular cell development and differentiation	87
In vivo self-assembly and delivery of VEGFR2 siRNA-encapsulated small extracellular vesicles for lung metastatic osteosarcoma therapy	86
SOX4-BMI1 axis promotes non-small cell lung cancer progression and facilitates angiogenesis by suppressing ZNF24	84
RNF115/BCA2 deficiency alleviated acute liver injury in mice by promoting autophagy and inhibiting inflammatory response	83
The role of SPATA2 in TNF signaling, cancer, and spermatogenesis	82
TRAIL protects the immature lung from hyperoxic injury	81
NADH:ubiquinone oxidoreductase core subunit S8 expression and functional significance in non-small cell lung cancer	80
USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma	78
Lysine methyltransferase SMYD2 inhibits antiviral innate immunity by promoting IRF3 dephosphorylation	77
CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3	77
Defective hematopoietic differentiation of immune aplastic anemia patient-derived iPSCs	77
p63, a key regulator of Ago2, links to the microRNA-144 cluster	77
Migration deficits of the neural crest caused by CXADR triplication in a human Down syndrome stem cell model	76
Nedd4-2 ablation in kidney improves glycaemic control in diabetic mice	76
Knockdown of Porf-2 restores visual function after optic nerve crush injury	76
IGFBP2/ITGA5 promotes gefitinib resistance via activating STAT3/CXCL1 axis in non-small cell lung cancer	76
Distinct functions of wild-type and R273H mutant Δ133p53α differentially regulate glioblastoma aggressiveness and therapy-induced senescence	76
The regulation, function, and role of lipophagy, a form of selective autophagy, in metabolic disorders	75
CD36 aggravates podocyte injury by activating NLRP3 inflammasome and inhibiting autophagy in lupus nephritis	74
Therapeutic role of PTEN in tissue regeneration for management of neurological disorders: stem cell behaviors to an in-depth review	74
m5C-dependent cross-regulation between nuclear reader ALYREF and writer NSUN2 promotes urothelial bladder cancer malignancy through facilitating RABL6/TK1 mRNAs splicing and stabilization	74
USP11-mediated LSH deubiquitination inhibits ferroptosis in colorectal cancer through epigenetic activation of CYP24A1	72
Regulatory T cells in skeletal muscle repair and regeneration: recent insights	72
FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression	72
m6A and m5C modification of GPX4 facilitates anticancer immunity via STING activation	72
The tyrosine-kinase inhibitor Nintedanib ameliorates autosomal-dominant polycystic kidney disease	71
A novel inhibitor of the mitochondrial respiratory complex I with uncoupling properties exerts potent antitumor activity	71
ER-mitochondria association negatively affects wound healing by regulating NLRP3 activation	70
TAB182 aggravates progression of esophageal squamous cell carcinoma by enhancing β-catenin nuclear translocation through FHL2 dependent manner	68
USP1 modulates hepatocellular carcinoma progression via the Hippo/TAZ axis	68
Correction to: Deubiquitylase OTUD6B stabilizes the mutated pVHL and suppresses cell migration in clear cell renal cell carcinoma	67
SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice	67
Nerve growth factor promotes lysyl oxidase-dependent chondrosarcoma cell metastasis by suppressing miR-149-5p synthesis	66
Angiotensin II related glial cell activation and necroptosis of retinal ganglion cells after systemic hypotension in glaucoma	66
Tumor-associated macrophage-derived exosomes transmitting miR-193a-5p promote the progression of renal cell carcinoma via TIMP2-dependent vasculogenic mimicry	66
Ascitic fluid shear stress in concert with hepatocyte growth factor drive stemness and chemoresistance of ovarian cancer cells via the c-Met-PI3K/Akt-miR-199a-3p signaling pathway	66
Retraction Note: Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer	65
PRMT1-mediated methylation of UBE2m promoting calcium oxalate crystal-induced kidney injury by inhibiting fatty acid metabolism	65
p21-activated kinase 4 controls the aggregation of α-synuclein by reducing the monomeric and aggregated forms of α-synuclein: involvement of the E3 ubiquitin ligase NEDD4-1	65
Correction to: Tumor-associated macrophage-derived exosomes transmitting miR-193a-5p promote the progression of renal cell carcinoma via TIMP2-dependent vasculogenic mimicry	65
Protein kinase G inhibition preserves photoreceptor viability and function in a new mouse model for autosomal dominant retinitis pigmentosa	65
MLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL10	65
USP7 promotes temozolomide resistance by stabilizing MGMT in glioblastoma	65
Downregulated liver-elevated long intergenic noncoding RNA (LINC02428) is a tumor suppressor that blocks KDM5B/IGF2BP1 positive feedback loop in hepatocellular carcinoma	65
TRIM26 deficiency enhancing liver regeneration through macrophage polarization and β-catenin pathway activation	64
Exosomal circTGFBR2 promotes hepatocellular carcinoma progression via enhancing ATG5 mediated protective autophagy	64
Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis	64
Glycolysis-related lncRNA TMEM105 upregulates LDHA to facilitate breast cancer liver metastasis via sponging miR-1208	64
Exosomes derived from mesenchymal stem cells in diabetes and diabetic complications	64
Chemotoxicity-induced exosomal lncFERO regulates ferroptosis and stemness in gastric cancer stem cells	63
Novel roles of luteinizing hormone (LH) in tissue regeneration-associated functions in endometrial stem cells	63
BNIP3 (BCL2 interacting protein 3) regulates pluripotency by modulating mitochondrial homeostasis via mitophagy	63
Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2 recruitment onto mitochondria and PARK2-PARK6 activity during mitophagy	63
Genome-wide identification of microRNA targets reveals positive regulation of the Hippo pathway by miR-122 during liver development	62
The mitochondrial ATP-dependent potassium channel (mitoKATP) controls skeletal muscle structure and function	62
Systemic mechanisms of necrotic cell debris clearance	62
O-GlcNAcylation inhibition redirects the response of colon cancer cells to chemotherapy from senescence to apoptosis	62
The kinase activity of integrin-linked kinase regulates cellular senescence in gastric cancer	61
Deficiency of PPP6C protects TNF-induced necroptosis through activation of TAK1	61
A novel function of STAT3β in suppressing interferon response improves outcome in acute myeloid leukemia	61
DDX5 deficiency drives non-canonical NF-κB activation and NRF2 expression, influencing sorafenib response and hepatocellular carcinoma progression	61
Opposing roles for GSK3β and ERK1-dependent phosphorylation of huntingtin during neuronal dysfunction and cell death in Huntington’s disease	61
Germline specific genes increase DNA double-strand break repair and radioresistance in lung adenocarcinoma cells	61
Nek2A prevents centrosome clustering and induces cell death in cancer cells via KIF2C interaction	61
SMOC2 promotes an epithelial-mesenchymal transition and a pro-metastatic phenotype in epithelial cells of renal cell carcinoma origin	61
MiR-122-5p regulates the mevalonate pathway by targeting p53 in non-small cell lung cancer	61
Downregulation of TPX2 impairs the antitumor activity of CD8+ T cells in hepatocellular carcinoma	61

Correction: MicroRNA-29a induces loss of 5-hydroxymethylcytosine and promotes metastasis of hepatocellular carcinoma through a TET–SOCS1–MMP9 signaling axis	60
Reduced protection of RIPK3-deficient mice against influenza by matrix protein 2 ectodomain targeted active and passive vaccination strategies	60
Balancing the functions of DNA extracellular traps in intracellular parasite infections: implications for host defense, disease pathology and therapy	60
MLK4 regulates DNA damage response and promotes triple-negative breast cancer chemoresistance	59
S1PR3-driven positive feedback loop sustains STAT3 activation and keratinocyte hyperproliferation in psoriasis	59
Retraction Note: Long noncoding RNA LINC01234 promotes serine hydroxymethyltransferase 2 expression and proliferation by competitively binding miR-642a-5p in colon cancer	59
Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss	59
STING dependent BAX-IRF3 signaling results in apoptosis during late-stage Coxiella burnetii infection	59
Wet-dry-wet drug screen leads to the synthesis of TS1, a novel compound reversing lung fibrosis through inhibition of myofibroblast differentiation	58
TNFAIP2 promotes HIF1α transcription and breast cancer angiogenesis by activating the Rac1-ERK-AP1 signaling axis	58
Transcription factor EB-mediated mesenchymal stem cell therapy induces autophagy and alleviates spinocerebellar ataxia type 3 defects in neuronal cells model	58
NAT10 mediates TLR2 to promote podocyte senescence in adriamycin-induced nephropathy	57
Loss of RNF41 promotes bladder cancer metastasis through increasing NUDC stability to enhance tubulin polymerization	57
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway	57
Repurposing MDM2 inhibitor RG7388 for TP53-mutant NSCLC: a p53-independent pyroptotic mechanism via ROS/p-p38/NOXA/caspase-3/GSDME axis	57
The feedback loop between MTA1 and MTA3/TRIM21 modulates stemness of breast cancer in response to estrogen	57
Hepatocyte DDX3X protects against drug-induced acute liver injury via controlling stress granule formation and oxidative stress	56
High dose androgen suppresses natural killer cytotoxicity of castration-resistant prostate cancer cells via altering AR/circFKBP5/miRNA-513a-5p/PD-L1 signals	56
Galectin-3 promotes secretion of proteases that decrease epithelium integrity in human colon cancer cells	56
MicroRNA miR-1275 coordinately regulates AEA/LPA signals via targeting FAAH in lipid metabolism reprogramming of gastric cancer	56
Tim-3+ decidual Mφs induced Th2 and Treg bias in decidual CD4+T cells and promoted pregnancy maintenance via CD132	56
Circulating miR-184 is a potential predictive biomarker of cardiac damage in Anderson–Fabry disease	56
Transglutaminase 2 associated with PI3K and PTEN in a membrane-bound signalosome platform blunts cell death	56
Innate and adaptive immune cell interaction drives inflammasome activation and hepatocyte apoptosis in murine liver injury from immune checkpoint inhibitors	56
GSDMD-dependent neutrophil extracellular traps promote macrophage-to-myofibroblast transition and renal fibrosis in obstructive nephropathy	56
Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer’s disease	56
Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans	56
Stanniocalcin 1 promotes lung metastasis of breast cancer by enhancing EGFR–ERK–S100A4 signaling	56
Histone methyltransferase Smyd2 drives adipogenesis via regulating STAT3 phosphorylation	56
The role of vitamin K and its antagonist in the process of ferroptosis-damaged RPE-mediated CNV	55
Retraction Note to: Expansion of monocytic myeloid-derived suppressor cells ameliorated intestinal inflammatory response by radiation through SOCS3 expression	55
Role of cardiolipins, mitochondria, and autophagy in the differentiation process activated by all-trans retinoic acid in acute promyelocytic leukemia	55
Metabolic gatekeepers: harnessing tumor-derived metabolites to optimize T cell-based immunotherapy efficacy in the tumor microenvironment	55
Inhibitory role of proguanil on the growth of bladder cancer via enhancing EGFR degradation and inhibiting its downstream signaling pathway to induce autophagy	55
Nuclear pore protein POM121 regulates subcellular localization and transcriptional activity of PPARγ	55
Trim21-mediated CCT2 ubiquitination suppresses malignant progression and promotes CD4+T cell activation in breast cancer	55
RIPK3 promoter hypermethylation in hepatocytes protects from bile acid-induced inflammation and necroptosis	55
Nitroglycerin: a comprehensive review in cancer therapy	55
Critical analysis of translational potential of rodent models of white matter pathology across a wide spectrum of human diseases	55
Aldolase B-driven lactagenesis and CEACAM6 activation promote cell renewal and chemoresistance in colorectal cancer through the Warburg effect	54
β‐arrestin 2 negatively regulates lung cancer progression by inhibiting the TRAF6 signaling axis for NF-κB activation and autophagy induced by TLR3 and TLR4	54
USP14/S100A11 axis promote colorectal cancer progression by inhibiting cell senescence	54
TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC4	54
A novel Hoxd13 mutation causes synpolydactyly and promotes osteoclast differentiation by regulating pSmad5/p65/c-Fos/Rank axis	54
YAP1 facilitates the pathogenesis of psoriasis via modulating keratinocyte proliferation and inflammation	53
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer	53
LncRNA FIRRE functions as a tumor promoter by interaction with PTBP1 to stabilize BECN1 mRNA and facilitate autophagy	53
LncRNA SNHG1 regulates neuroblastoma cell fate via interactions with HDAC1/2	53
Androgen-targeted hsa_circ_0085121 encodes a novel protein and improves the development of prostate cancer through facilitating the activity of PI3K/Akt/mTOR pathway and enhancing AR-V7 alternative sp	53
CircNEIL3 mediates pyroptosis to influence lung adenocarcinoma radiotherapy by upregulating PIF1 through miR-1184 inhibition	53
CD146 regulates the stemness and chemoresistance of hepatocellular carcinoma via JAG2-NOTCH signaling	53
A positive feedback loop of lncRNA-RMRP/ZNRF3 axis and Wnt/β-catenin signaling regulates the progression and temozolomide resistance in glioma	53
SUMOylation of PDPK1 Is required to maintain glycolysis-dependent CD4 T-cell homeostasis	53
Targeting metabolic vulnerability by combining NAMPT inhibitors and disulfiram for treatment of recurrent ovarian cancer	52
Generation of functional neurons from adult human mucosal olfactory ensheathing glia by direct lineage conversion	52
Polymeric immunoglobulin receptor deficiency exacerbates autoimmune hepatitis by inducing intestinal dysbiosis and barrier dysfunction	52
CENPT prevents renal cell carcinoma against ferroptosis by enhancing the synthesis of glutathione	52
Card9 protects sepsis by regulating Ripk2-mediated activation of NLRP3 inflammasome in macrophages	52
Correction: SETD8 inhibits apoptosis and ferroptosis of Ewing’s sarcoma through YBX1/RAC3 axis	52
Targeting tumor suppressor p53 for organ fibrosis therapy	52
Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia	52
PAK6 rescues pathogenic LRRK2-mediated ciliogenesis and centrosomal cohesion defects in a mutation-specific manner	52
LINC00924-induced fatty acid metabolic reprogramming facilitates gastric cancer peritoneal metastasis via hnRNPC-regulated alternative splicing of Mnk2	52
Novel FABP4+C1q+ macrophages enhance antitumor immunity and associated with response to neoadjuvant pembrolizumab and chemotherapy in NSCLC via AMPK/JAK/STAT axis	51
Inhibition of ATM enhances the immunogenicity of triple-negative breast cancer by promoting MHC-I expression	51
The ALDH2/PolG2 axis enhances mitochondrial biogenesis via transcriptional regulation of Nrf2 and promotes chemotherapy resistance in acute myeloid leukaemia	51
TGF-β-induced PLEK2 promotes metastasis and chemoresistance in oesophageal squamous cell carcinoma by regulating LCN2	50
FRMD3 inhibits the growth and metastasis of breast cancer through the ubiquitination-mediated degradation of vimentin and subsequent impairment of focal adhesion	50
Non-enzymatic role of SOD1 in intestinal stem cell growth	50
The oleic/palmitic acid imbalance in exosomes isolated from NAFLD patients induces necroptosis of liver cells via the elongase-6/RIP-1 pathway	50
TNFAIP8 protein functions as a tumor suppressor in inflammation-associated colorectal tumorigenesis	50
The CRTC-CREB axis functions as a transcriptional sensor to protect against proteotoxic stress in Drosophila	50
TP63 as a modulator of ferroptosis in TP53 mutations glioblastoma	50
Autolysosomes and caspase-3 control the biogenesis and release of immunogenic apoptotic exosomes	50
CSE reduces OTUD4 triggering lung epithelial cell apoptosis via PAI-1 degradation	50
CAF-derived exosomal WEE2-AS1 facilitates colorectal cancer progression via promoting degradation of MOB1A to inhibit the Hippo pathway	49
Cerebral endothelial cell-derived extracellular vesicles regulate microglial polarization and promote autophagy via delivery of miR-672-5p	49
PTRF-IL33-ZBP1 signaling mediating macrophage necroptosis contributes to HDM-induced airway inflammation	49
Retraction Note: Identification of protein kinase inhibitors to reprogram breast cancer cells	49
Transglutaminase 2 function in glioblastoma tumor efferocytosis	49
Versatile enhancement of the killing potential of anti-cancer agents achieved by peptide mimetics of the PCNA interface towards specialized DNA polymerases	49
Correction to: Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells	48
Inhibition of the immunoproteasome modulates innate immunity to ameliorate muscle pathology of dysferlin-deficient BlAJ mice	48
Retraction Note: Involvement of autophagy in hypoxia-BNIP3 signaling to promote epidermal keratinocyte migration	48
Selective deletion of E3 ubiquitin ligase FBW7 in VE-cadherin-positive cells instigates diffuse large B-cell lymphoma in mice in vivo	48
Correction to: ONECUT2 facilitates hepatocellular carcinoma metastasis by transcriptionally upregulating FGF2 and ACLY	48
Retraction Note: RUNX3-regulated circRNA METTL3 inhibits colorectal cancer proliferation and metastasis via miR-107/PER3 axis	47
In vivo restoration of dystrophin expression in mdx mice using intra-muscular and intra-arterial injections of hydrogel microsphere carriers of exon skipping antisense oligonucleotides	47
Correction: Tumor-educated B cells promote renal cancer metastasis via inducing the IL-1β/HIF-2α/Notch1 signals	47
Endothelial cell-derived RSPO3 activates Gαi1/3-Erk signaling and protects neurons from ischemia/reperfusion injury	47
The deubiquitinating enzyme OTUD7b protects dendritic cells from TNF-induced apoptosis by stabilizing the E3 ligase TRAF2	47
Non-canonical functions of spliceosome components in cancer progression	47
MiR-1246b, a novel miRNA molecule of extracellular vesicles in bronchoalveolar lavage fluid, promotes nodule growth through FGF14 in patients with lung cancer	46
LMO2 promotes the development of AML through interaction with transcription co-regulator LDB1	46
AURKAIP1 actuates tumor progression through stabilizing DDX5 in triple negative breast cancer	46