Cell Death & Disease

Article	Citations
Detection of immunogenic cell death and its relevance for cancer therapy	474
PI3K/AKT pathway as a key link modulates the multidrug resistance of cancers	387
Regulated cell death pathways in doxorubicin-induced cardiotoxicity	281
NLRP3 inflammasome in endothelial dysfunction	245
Understanding lipotoxicity in NAFLD pathogenesis: is CD36 a key driver?	229
CircRNA hsa_circRNA_104348 promotes hepatocellular carcinoma progression through modulating miR-187-3p/RTKN2 axis and activating Wnt/β-catenin pathway	196
CircRNAs: role in human diseases and potential use as biomarkers	193
N6-methyladenosine METTL3 promotes cervical cancer tumorigenesis and Warburg effect through YTHDF1/HK2 modification	159
Advances in the pathogenesis of psoriasis: from keratinocyte perspective	154
RNA-based therapeutics: an overview and prospectus	152
Legumain promotes tubular ferroptosis by facilitating chaperone-mediated autophagy of GPX4 in AKI	152
The therapeutic potential of mesenchymal stem cells for cardiovascular diseases	152
GSTZ1 sensitizes hepatocellular carcinoma cells to sorafenib-induced ferroptosis via inhibition of NRF2/GPX4 axis	152
Scutellarin ameliorates pulmonary fibrosis through inhibiting NF-κB/NLRP3-mediated epithelial–mesenchymal transition and inflammation	149
Characterization of ferroptosis in kidney tubular cell death under diabetic conditions	141
Mitochondria in skin health, aging, and disease	140
Cetuximab promotes RSL3-induced ferroptosis by suppressing the Nrf2/HO-1 signalling pathway in KRAS mutant colorectal cancer	136
Excessive phospholipid peroxidation distinguishes ferroptosis from other cell death modes including pyroptosis	134
Mesenchymal stem cell-derived extracellular vesicles for immunomodulation and regeneration: a next generation therapeutic tool?	134
MT1DP loaded by folate-modified liposomes sensitizes erastin-induced ferroptosis via regulating miR-365a-3p/NRF2 axis in non-small cell lung cancer cells	129
Bioactive DNA from extracellular vesicles and particles	126
Autophagy as a modulator of cell death machinery	123
Targeting BCL-2 in B-cell malignancies and overcoming therapeutic resistance	121
XJB-5-131 inhibited ferroptosis in tubular epithelial cells after ischemia−reperfusion injury	121
PD-L1 degradation pathway and immunotherapy for cancer	117

miR-182-5p and miR-378a-3p regulate ferroptosis in I/R-induced renal injury	116
High-fat diet promotes renal injury by inducing oxidative stress and mitochondrial dysfunction	114
Fin56-induced ferroptosis is supported by autophagy-mediated GPX4 degradation and functions synergistically with mTOR inhibition to kill bladder cancer cells	114
Mesenchymal stem cells reverse EMT process through blocking the activation of NF-κB and Hedgehog pathways in LPS-induced acute lung injury	114
Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload	113
The role of m6A modification in physiology and disease	113
MYC-targeted WDR4 promotes proliferation, metastasis, and sorafenib resistance by inducing CCNB1 translation in hepatocellular carcinoma	110
Metabolomic analyses of COVID-19 patients unravel stage-dependent and prognostic biomarkers	110
TNF-alpha-induced microglia activation requires miR-342: impact on NF-kB signaling and neurotoxicity	108
Caspase 3/GSDME-dependent pyroptosis contributes to chemotherapy drug-induced nephrotoxicity	108
Macrophage-derived extracellular vesicles: diverse mediators of pathology and therapeutics in multiple diseases	108
CircRNA_09505 aggravates inflammation and joint damage in collagen-induced arthritis mice via miR-6089/AKT1/NF-κB axis	103
Exosomes and breast cancer drug resistance	103
Interaction between macrophages and ferroptosis	102
The mechanism of m6A methyltransferase METTL3-mediated autophagy in reversing gefitinib resistance in NSCLC cells by β-elemene	101
STING promotes senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the NF-κB signaling pathway	101
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype	101
TGF-β1-mediated repression of SLC7A11 drives vulnerability to GPX4 inhibition in hepatocellular carcinoma cells	100
Deep sequencing of circulating tumor DNA detects molecular residual disease and predicts recurrence in gastric cancer	100
Stabilization of HIF-1α alleviates osteoarthritis via enhancing mitophagy	98
TRPV1 alleviates osteoarthritis by inhibiting M1 macrophage polarization via Ca2+/CaMKII/Nrf2 signaling pathway	98
TLR4 promotes microglial pyroptosis via lncRNA-F630028O10Rik by activating PI3K/AKT pathway after spinal cord injury	98
Extracellular vesicles from human embryonic stem cell-derived cardiovascular progenitor cells promote cardiac infarct healing through reducing cardiomyocyte death and promoting angiogenesis	96
Hypoxic glioma-derived exosomes promote M2-like macrophage polarization by enhancing autophagy induction	95
Sodium–glucose cotransporter 2 inhibition suppresses HIF-1α-mediated metabolic switch from lipid oxidation to glycolysis in kidney tubule cells of diabetic mice	94
The emerging role of ferroptosis in intestinal disease	94
anlotinib alters tumor immune microenvironment by downregulating PD-L1 expression on vascular endothelial cells	93
Sorafenib fails to trigger ferroptosis across a wide range of cancer cell lines	93
Tetraarsenic hexoxide enhances generation of mitochondrial ROS to promote pyroptosis by inducing the activation of caspase-3/GSDME in triple-negative breast cancer cells	93
Which cell death modality wins the contest for photodynamic therapy of cancer?	91
Evidences for lipid involvement in SARS-CoV-2 cytopathogenesis	91
Early expansion of myeloid-derived suppressor cells inhibits SARS-CoV-2 specific T-cell response and may predict fatal COVID-19 outcome	91
Exosomal miR-25-3p from mesenchymal stem cells alleviates myocardial infarction by targeting pro-apoptotic proteins and EZH2	90
DHA exhibits synergistic therapeutic efficacy with cisplatin to induce ferroptosis in pancreatic ductal adenocarcinoma via modulation of iron metabolism	90
METTL14-regulated PI3K/Akt signaling pathway via PTEN affects HDAC5-mediated epithelial–mesenchymal transition of renal tubular cells in diabetic kidney disease	88
LncRNA RP11-89 facilitates tumorigenesis and ferroptosis resistance through PROM2-activated iron export by sponging miR-129-5p in bladder cancer	87
Age-severity matched cytokine profiling reveals specific signatures in Covid-19 patients	86
Cancer-derived exosomal HSPC111 promotes colorectal cancer liver metastasis by reprogramming lipid metabolism in cancer-associated fibroblasts	86
AMPK agonist alleviate renal tubulointerstitial fibrosis via activating mitophagy in high fat and streptozotocin induced diabetic mice	85
The fatty acid receptor CD36 promotes HCC progression through activating Src/PI3K/AKT axis-dependent aerobic glycolysis	85
Mitochondrial autophagy: molecular mechanisms and implications for cardiovascular disease	85
Gasdermin E deficiency attenuates acute kidney injury by inhibiting pyroptosis and inflammation	84
Arsenic trioxide induces macrophage autophagy and atheroprotection by regulating ROS-dependent TFEB nuclear translocation and AKT/mTOR pathway	84
AFP promotes HCC progression by suppressing the HuR-mediated Fas/FADD apoptotic pathway	83
A novel N6-methyladenosine (m6A)-dependent fate decision for the lncRNA THOR	83
Mitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis	83
A cross-talk between epithelium and endothelium mediates human alveolar–capillary injury during SARS-CoV-2 infection	82
WTAP promotes osteosarcoma tumorigenesis by repressing HMBOX1 expression in an m6A-dependent manner	82
WNT/β-catenin-suppressed FTO expression increases m6A of c-Myc mRNA to promote tumor cell glycolysis and tumorigenesis	81
PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer	81

CSF1R signaling is a regulator of pathogenesis in progressive MS	80
Nrf2 attenuates ferroptosis-mediated IIR-ALI by modulating TERT and SLC7A11	80
SOX2 promotes chemoresistance, cancer stem cells properties, and epithelial–mesenchymal transition by β-catenin and Beclin1/autophagy signaling in colorectal cancer	79
Bone marrow mesenchymal stem cells-derived exosomal microRNA-193a reduces cisplatin resistance of non-small cell lung cancer cells via targeting LRRC1	78
Mex3a interacts with LAMA2 to promote lung adenocarcinoma metastasis via PI3K/AKT pathway	78
Discovery of a novel ferroptosis inducer-talaroconvolutin A—killing colorectal cancer cells in vitro and in vivo	78
The emerging role of ferroptosis in non-cancer liver diseases: hype or increasing hope?	77
Alpha-synuclein in Parkinson’s disease and other synucleinopathies: from overt neurodegeneration back to early synaptic dysfunction	77
M2 macrophage-induced lncRNA PCAT6 facilitates tumorigenesis and angiogenesis of triple-negative breast cancer through modulation of VEGFR2	77
Cancer-secreted exosomal miR-21-5p induces angiogenesis and vascular permeability by targeting KRIT1	77
Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation?	76
SARS-CoV-2 infection is associated with a pro-thrombotic platelet phenotype	75
GPX4 and vitamin E cooperatively protect hematopoietic stem and progenitor cells from lipid peroxidation and ferroptosis	75
Ionizing radiation results in a mixture of cellular outcomes including mitotic catastrophe, senescence, methuosis, and iron-dependent cell death	74
p27 controls autophagic vesicle trafficking in glucose-deprived cells via the regulation of ATAT1-mediated microtubule acetylation	74
YTHDC1 mitigates ischemic stroke by promoting Akt phosphorylation through destabilizing PTEN mRNA	73
Osteocyte apoptosis: the roles and key molecular mechanisms in resorption-related bone diseases	73
Sitagliptin activates the p62–Keap1–Nrf2 signalling pathway to alleviate oxidative stress and excessive autophagy in severe acute pancreatitis-related acute lung injury	73
Long noncoding RNA UCA1 from hypoxia-conditioned hMSC-derived exosomes: a novel molecular target for cardioprotection through miR-873-5p/XIAP axis	73
NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation	73
The circEPSTI1/mir-942-5p/LTBP2 axis regulates the progression of OSCC in the background of OSF via EMT and the PI3K/Akt/mTOR pathway	72
Depletion of microglia exacerbates injury and impairs function recovery after spinal cord injury in mice	72
MCL-1Matrix maintains neuronal survival by enhancing mitochondrial integrity and bioenergetic capacity under stress conditions	72
Is hydroxychloroquine beneficial for COVID-19 patients?	72
Inhibition of keratinocyte ferroptosis suppresses psoriatic inflammation	72
MYCN mediates TFRC-dependent ferroptosis and reveals vulnerabilities in neuroblastoma	71
ALKBH5 suppresses tumor progression via an m6A-dependent epigenetic silencing of pre-miR-181b-1/YAP signaling axis in osteosarcoma	70
mtDNA-STING pathway promotes necroptosis-dependent enterocyte injury in intestinal ischemia reperfusion	70
The redox language in neurodegenerative diseases: oxidative post-translational modifications by hydrogen peroxide	70
Mesenchymal stem cells protect against ferroptosis via exosome-mediated stabilization of SLC7A11 in acute liver injury	70
Liproxstatin-1 attenuates unilateral ureteral obstruction-induced renal fibrosis by inhibiting renal tubular epithelial cells ferroptosis	70
Long noncoding RNA SNHG12 promotes tumour progression and sunitinib resistance by upregulating CDCA3 in renal cell carcinoma	69
SIRT1 attenuates sepsis-induced acute kidney injury via Beclin1 deacetylation-mediated autophagy activation	69
LncRNA kcnq1ot1 promotes lipid accumulation and accelerates atherosclerosis via functioning as a ceRNA through the miR-452-3p/HDAC3/ABCA1 axis	69
STING agonist diABZI induces PANoptosis and DNA mediated acute respiratory distress syndrome (ARDS)	69
Ferroptosis: the potential value target in atherosclerosis	68
LncRNA SOX2OT promotes temozolomide resistance by elevating SOX2 expression via ALKBH5-mediated epigenetic regulation in glioblastoma	68
Cell-cycle arrest and senescence in TP53-wild type renal carcinoma by enhancer RNA-P53-bound enhancer regions 2 (p53BER2) in a p53-dependent pathway	68
A novel circular RNA, circXPO1, promotes lung adenocarcinoma progression by interacting with IGF2BP1	68
Adipose tissue aging: mechanisms and therapeutic implications	68
The regulation, function, and role of lipophagy, a form of selective autophagy, in metabolic disorders	67
Tumor-derived exosomal circPSMA1 facilitates the tumorigenesis, metastasis, and migration in triple-negative breast cancer (TNBC) through miR-637/Akt1/β-catenin (cyclin D1) axis	67
COVID-19 infection: the China and Italy perspectives	67
Double-edge sword roles of iron in driving energy production versus instigating ferroptosis	66
Cannabidiol (CBD): a killer for inflammatory rheumatoid arthritis synovial fibroblasts	66
DPP8/9 inhibitors activate the CARD8 inflammasome in resting lymphocytes	66
IFN-γ promoted exosomes from mesenchymal stem cells to attenuate colitis via miR-125a and miR-125b	65
Exosome-transferred LINC01559 promotes the progression of gastric cancer via PI3K/AKT signaling pathway	65
Targeting ferroptosis in acute kidney injury	65
N6-methyladenosine modification of circCUX1 confers radioresistance of hypopharyngeal squamous cell carcinoma through caspase1 pathway	64
Lysosomal quality control of cell fate: a novel therapeutic target for human diseases	64
MicroRNA-377-3p released by mesenchymal stem cell exosomes ameliorates lipopolysaccharide-induced acute lung injury by targeting RPTOR to induce autophagy	64
OPA1 and MICOS Regulate mitochondrial crista dynamics and formation	64
HucMSC-derived exosomes delivered BECN1 induces ferroptosis of hepatic stellate cells via regulating the xCT/GPX4 axis	63
Anlotinib suppresses tumor progression via blocking the VEGFR2/PI3K/AKT cascade in intrahepatic cholangiocarcinoma	63
METTL14 suppresses pyroptosis and diabetic cardiomyopathy by downregulating TINCR lncRNA	63
The inhibition of IL-2/IL-2R gives rise to CD8+ T cell and lymphocyte decrease through JAK1-STAT5 in critical patients with COVID-19 pneumonia	63
Circ_0008542 in osteoblast exosomes promotes osteoclast-induced bone resorption through m6A methylation	62
Neutrophils undergo switch of apoptosis to NETosis during murine fatty liver injury via S1P receptor 2 signaling	62
The miR-30a-5p/CLCF1 axis regulates sorafenib resistance and aerobic glycolysis in hepatocellular carcinoma	62
Extracellular vesicle-mediated transfer of miR-21-5p from mesenchymal stromal cells to neurons alleviates early brain injury to improve cognitive function via the PTEN/Akt pathway after subarachnoid h	62
Age-related cerebral small vessel disease and inflammaging	62
Acyl-CoA thioesterase 1 prevents cardiomyocytes from Doxorubicin-induced ferroptosis via shaping the lipid composition	62
Disruption of Atg7-dependent autophagy causes electromotility disturbances, outer hair cell loss, and deafness in mice	62
Oleandrin, a cardiac glycoside, induces immunogenic cell death via the PERK/elF2α/ATF4/CHOP pathway in breast cancer	61
Intracellular amyloid toxicity induces oxytosis/ferroptosis regulated cell death	61
Long non-coding RNA CASC9 promotes gefitinib resistance in NSCLC by epigenetic repression of DUSP1	61
Exosomal LGALS9 in the cerebrospinal fluid of glioblastoma patients suppressed dendritic cell antigen presentation and cytotoxic T-cell immunity	61
Small-molecule inhibition of APE1 induces apoptosis, pyroptosis, and necroptosis in non-small cell lung cancer	60
The emerging roles of neutrophil extracellular traps in wound healing	60
Cellular senescence contributes to radiation-induced hyposalivation by affecting the stem/progenitor cell niche	60
LncRNA ANRIL acts as a modular scaffold of WDR5 and HDAC3 complexes and promotes alteration of the vascular smooth muscle cell phenotype	60
Exosomes derived from hucMSC attenuate renal fibrosis through CK1δ/β-TRCP-mediated YAP degradation	60
Neutrophil extracellular traps impair intestinal barrier functions in sepsis by regulating TLR9-mediated endoplasmic reticulum stress pathway	59
Cancer cell metabolic reprogramming: a keystone for the response to immunotherapy	59
A miR-210-3p regulon that controls the Warburg effect by modulating HIF-1α and p53 activity in triple-negative breast cancer	59
Oncogenic driver genes and tumor microenvironment determine the type of liver cancer	58
A long way to go: caspase inhibitors in clinical use	58
M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway	58
Fine tuning of the unfolded protein response by ISRIB improves neuronal survival in a model of amyotrophic lateral sclerosis	58

LncRNA-MIAT promotes thyroid cancer progression and function as ceRNA to target EZH2 by sponging miR-150-5p	58
Strategies and prospects of effective neural circuits reconstruction after spinal cord injury	58
COVID19: an announced pandemic	58
M2 macrophage-derived exosomal long non-coding RNA AGAP2-AS1 enhances radiotherapy immunity in lung cancer by reducing microRNA-296 and elevating NOTCH2	58
A new risk factor indicator for papillary thyroid cancer based on immune infiltration	57
m6A methylated EphA2 and VEGFA through IGF2BP2/3 regulation promotes vasculogenic mimicry in colorectal cancer via PI3K/AKT and ERK1/2 signaling	57
Endoplasmic reticulum stress-mediated cell death in liver injury	57
Calcium and TRPV4 promote metastasis by regulating cytoskeleton through the RhoA/ROCK1 pathway in endometrial cancer	57
Wnt/β-catenin signaling pathway induces autophagy-mediated temozolomide-resistance in human glioblastoma	57
LncRNA linc00312 suppresses radiotherapy resistance by targeting DNA-PKcs and impairing DNA damage repair in nasopharyngeal carcinoma	57
TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells	57
Quercetin promotes in vitro maturation of oocytes from humans and aged mice	57
Mechanical stretch promotes hypertrophic scar formation through mechanically activated cation channel Piezo1	56
Extracellular vesicles from hypoxia-preconditioned microglia promote angiogenesis and repress apoptosis in stroke mice via the TGF-β/Smad2/3 pathway	56
Altered mitochondrial dynamics and function in APOE4-expressing astrocytes	56
Stem/progenitor cell-based transplantation for retinal degeneration: a review of clinical trials	55
Tumor exosome promotes Th17 cell differentiation by transmitting the lncRNA CRNDE-h in colorectal cancer	55
Programmed cell death in atherosclerosis and vascular calcification	55
RNA binding protein NKAP protects glioblastoma cells from ferroptosis by promoting SLC7A11 mRNA splicing in an m6A-dependent manner	55
Ginsenoside Rg3 promotes regression from hepatic fibrosis through reducing inflammation-mediated autophagy signaling pathway	55
Exosome-derived ENO1 regulates integrin α6β4 expression and promotes hepatocellular carcinoma growth and metastasis	55
Internalization mechanisms of brain-derived tau oligomers from patients with Alzheimer’s disease, progressive supranuclear palsy and dementia with Lewy bodies	55
Mitochondrial ClpP serine protease-biological function and emerging target for cancer therapy	55
Acid sphingomyelinase-dependent autophagic degradation of GPX4 is critical for the execution of ferroptosis	55
CD36 promotes NLRP3 inflammasome activation via the mtROS pathway in renal tubular epithelial cells of diabetic kidneys	55
Cancer-associated fibroblast-derived CXCL11 modulates hepatocellular carcinoma cell migration and tumor metastasis through the circUBAP2/miR-4756/IFIT1/3 axis	55
RNA m6A reader YTHDF2 facilitates lung adenocarcinoma cell proliferation and metastasis by targeting the AXIN1/Wnt/β-catenin signaling	54
Extracellular vesicles in ovarian cancer chemoresistance, metastasis, and immune evasion	54
ER stress and UPR in Alzheimer’s disease: mechanisms, pathogenesis, treatments	54
METTL14 aggravates podocyte injury and glomerulopathy progression through N6-methyladenosine-dependent downregulating of Sirt1	54
NLPR3 inflammasome inhibition alleviates hypoxic endothelial cell death in vitro and protects blood–brain barrier integrity in murine stroke	54
(+)-Clausenamide protects against drug-induced liver injury by inhibiting hepatocyte ferroptosis	54
Zinc transporter ZIP7 is a novel determinant of ferroptosis	54
Interactions between m6A modification and miRNAs in malignant tumors	54
LncRNA LINC00472 regulates cell stiffness and inhibits the migration and invasion of lung adenocarcinoma by binding to YBX1	54
Oxidative stress-mediated mitochondrial dysfunction facilitates mesenchymal stem cell senescence in ankylosing spondylitis	54
The interaction between ferroptosis and inflammatory signaling pathways	54
Circular RNA circNRIP1 promotes migration and invasion in cervical cancer by sponging miR-629-3p and regulating the PTP4A1/ERK1/2 pathway	53
Echinatin suppresses esophageal cancer tumor growth and invasion through inducing AKT/mTOR-dependent autophagy and apoptosis	53
Delayed treatment with an autophagy inhibitor 3-MA alleviates the progression of hyperuricemic nephropathy	53
Circulating mitochondrial DNA-triggered autophagy dysfunction via STING underlies sepsis-related acute lung injury	52
Mutant p53 in cancer: from molecular mechanism to therapeutic modulation	52
CircAGFG1 drives metastasis and stemness in colorectal cancer by modulating YY1/CTNNB1	52
The crosstalk between HIFs and mitochondrial dysfunctions in cancer development	52
Enolase 1 regulates stem cell-like properties in gastric cancer cells by stimulating glycolysis	52
ω-6 Polyunsaturated fatty acids (linoleic acid) activate both autophagy and antioxidation in a synergistic feedback loop via TOR-dependent and TOR-independent signaling pathways	52
Lipid peroxidation and the subsequent cell death transmitting from ferroptotic cells to neighboring cells	51
Copper homeostasis and copper-induced cell death in the pathogenesis of cardiovascular disease and therapeutic strategies	51
CircRAB11FIP1 promoted autophagy flux of ovarian cancer through DSC1 and miR-129	51
Phosphorylation of eukaryotic initiation factor-2α (eIF2α) in autophagy	51
Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts	51
Exosomal circ_DLGAP4 promotes diabetic kidney disease progression by sponging miR-143 and targeting ERBB3/NF-κB/MMP-2 axis	51
Induction of ferroptosis in human nasopharyngeal cancer cells by cucurbitacin B: molecular mechanism and therapeutic potential	51
SIRT6 promotes angiogenesis and hemorrhage of carotid plaque via regulating HIF-1α and reactive oxygen species	51
High glucose mediates NLRP3 inflammasome activation via upregulation of ELF3 expression	50
YTHDF1 promotes breast cancer cell growth, DNA damage repair and chemoresistance	50
Protein lysine crotonylation: past, present, perspective	50
LncRNA MM2P-induced, exosome-mediated transfer of Sox9 from monocyte-derived cells modulates primary chondrocytes	50
Heme oxygenase 1 protects human colonocytes against ROS formation, oxidative DNA damage and cytotoxicity induced by heme iron, but not inorganic iron	49
Osteocrin, a novel myokine, prevents diabetic cardiomyopathy via restoring proteasomal activity	49
STAT6 inhibits ferroptosis and alleviates acute lung injury via regulating P53/SLC7A11 pathway	49
Isoliquiritigenin prevents hyperglycemia-induced renal injuries by inhibiting inflammation and oxidative stress via SIRT1-dependent mechanism	49
Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition	49
Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer	49
Crosstalk between noncoding RNAs and ferroptosis: new dawn for overcoming cancer progression	49
A gene toolbox for monitoring autophagy transcription	49
High glucose induces Drp1-mediated mitochondrial fission via the Orai1 calcium channel to participate in diabetic cardiomyocyte hypertrophy	49
Single cell transcriptional zonation of human psoriasis skin identifies an alternative immunoregulatory axis conducted by skin resident cells	49
LDHA induces EMT gene transcription and regulates autophagy to promote the metastasis and tumorigenesis of papillary thyroid carcinoma	48
CISD3 inhibition drives cystine-deprivation induced ferroptosis	48
circ5615 functions as a ceRNA to promote colorectal cancer progression by upregulating TNKS	48
Irradiation induces cancer lung metastasis through activation of the cGAS–STING–CCL5 pathway in mesenchymal stromal cells	48
Iron-overloaded follicular fluid increases the risk of endometriosis-related infertility by triggering granulosa cell ferroptosis and oocyte dysmaturity	48
BCG vaccination policy and preventive chloroquine usage: do they have an impact on COVID-19 pandemic?	48
N6-methyladenosine-dependent pri-miR-17-92 maturation suppresses PTEN/TMEM127 and promotes sensitivity to everolimus in gastric cancer	48
Targeted P2X7/NLRP3 signaling pathway against inflammation, apoptosis, and pyroptosis of retinal endothelial cells in diabetic retinopathy	47
The roles of long noncoding RNAs in breast cancer metastasis	47
Tumor-derived exosomal components: the multifaceted roles and mechanisms in breast cancer metastasis	47
Inhibiting NLRP3 inflammasome activation prevents copper-induced neuropathology in a murine model of Wilson’s disease	47
Oxygen glucose deprivation/re-oxygenation-induced neuronal cell death is associated with Lnc-D63785 m6A methylation and miR-422a accumulation	47
LncRNA H19 governs mitophagy and restores mitochondrial respiration in the heart through Pink1/Parkin signaling during obesity	47
Circ-ADAM9 targeting PTEN and ATG7 promotes autophagy and apoptosis of diabetic endothelial progenitor cells by sponging mir-20a-5p	46
Short lifespan of syngeneic transplanted MSC is a consequence of in vivo apoptosis and immune cell recruitment in mice	46
Exosomal lncRNA DOCK9-AS2 derived from cancer stem cell-like cells activated Wnt/β-catenin pathway to aggravate stemness, proliferation, migration, and invasion in papillary thyroid carcinoma	46
BNIP3L/NIX-mediated mitophagy: molecular mechanisms and implications for human disease	46
Effects of short-chain fatty acids in inhibiting HDAC and activating p38 MAPK are critical for promoting B10 cell generation and function	46
Adipocyte death triggers a pro-inflammatory response and induces metabolic activation of resident macrophages	46
Cancer-associated fibroblasts-mediated ATF4 expression promotes malignancy and gemcitabine resistance in pancreatic cancer via the TGF-β1/SMAD2/3 pathway and ABCC1 transactivation	46
Interactions between gastric microbiota and metabolites in gastric cancer	46
Hypoxia induces sorafenib resistance mediated by autophagy via activating FOXO3a in hepatocellular carcinoma	46
Interleukin-38 ameliorates poly(I:C) induced lung inflammation: therapeutic implications in respiratory viral infections	45
LncRNA CRNDE facilitates epigenetic suppression of CELF2 and LATS2 to promote proliferation, migration and chemoresistance in hepatocellular carcinoma	45
Chemotoxicity-induced exosomal lncFERO regulates ferroptosis and stemness in gastric cancer stem cells	45
Kartogenin prevents cartilage degradation and alleviates osteoarthritis progression in mice via the miR-146a/NRF2 axis	45
Inhibition of miR-450b-5p ameliorates hepatic ischemia/reperfusion injury via targeting CRYAB	45