Cell Death & Disease

Article	Citations
Adding pieces to the puzzle of differentiated-to-anaplastic thyroid cancer evolution: the oncogene E2F7	493
Correction: TRPM8 contributes to liver regeneration via mitochondrial energy metabolism mediated by PGC1α	411
The Janus face of endogenous neuronal tPA: promoting self-protection and worsening the death of neighboring neurons	405
FOXA1 prevents nutrients deprivation induced autophagic cell death through inducing loss of imprinting of IGF2 in lung adenocarcinoma	394
Dominant-negative p53-overexpression in skeletal muscle induces cell death and fiber atrophy in rats	369
Correction: Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells	281
Correction: Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis	270
Correction: Adipose-derived mesenchymal stromal cells promote corneal wound healing by accelerating the clearance of neutrophils in cornea	255
Single-cell RNA-seq and pathological phenotype reveal the functional atlas and precise roles of Sox30 in testicular cell development and differentiation	243
Differential kinetics of splenic CD169+ macrophage death is one underlying cause of virus infection fate regulation	219
ZBTB7B is a permissive regulator of hepatocellular carcinoma initiation by repressing c-Jun expression and function	213
Therapeutic efficacy of TMTP1-modified EVs in overcoming bone metastasis and immune resistance in PIK3CA mutant NSCLC	205
FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression	201
p53-loss induced prostatic epithelial cell plasticity and invasion is driven by a crosstalk with the tumor microenvironment	195
Defective hematopoietic differentiation of immune aplastic anemia patient-derived iPSCs	191
p63, a key regulator of Ago2, links to the microRNA-144 cluster	182
Lysine methyltransferase SMYD2 inhibits antiviral innate immunity by promoting IRF3 dephosphorylation	176
NADH:ubiquinone oxidoreductase core subunit S8 expression and functional significance in non-small cell lung cancer	169
USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma	169
Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibition	167
TRAIL protects the immature lung from hyperoxic injury	165
ATRA upregulates OTUD6B to recruit CD8+ T cells to suppress colorectal liver metastasis by stabilizing DDX5/STAT3/CXCL11 axis	164
MicroRNA miR-20a-5p targets CYCS to inhibit apoptosis in hepatocellular carcinoma	163
Zipper-interacting protein kinase mediates neuronal cell death and cognitive dysfunction in traumatic brain injury via regulating DEDD	162
CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3	156

Nedd4-2 ablation in kidney improves glycaemic control in diabetic mice	155
PRMT1-mediated EZH2 methylation promotes breast cancer cell proliferation and tumorigenesis	155
PD-L1 induces autophagy and primary resistance to EGFR–TKIs in EGFR-mutant lung adenocarcinoma via the MAPK signaling pathway	153
Distinct functions of wild-type and R273H mutant Δ133p53α differentially regulate glioblastoma aggressiveness and therapy-induced senescence	151
Long noncoding RNA LINC01594 inhibits the CELF6-mediated splicing of oncogenic CD44 variants to promote colorectal cancer metastasis	148
RNAi-based ALOX15B silencing augments keratinocyte inflammation in vitro via EGFR/STAT1/JAK1 signalling	146
Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma	145
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation	140
KLF13 promotes esophageal cancer progression and regulates triacylglyceride and free fatty acid metabolism through GPIHBP1	137
Endothelial ETS1 inhibition exacerbate blood–brain barrier dysfunction in multiple sclerosis through inducing endothelial-to-mesenchymal transition	137
Overexpression of EphB6 and EphrinB2 controls soma spacing of cortical neurons in a mutual inhibitory way	135
Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation	134
Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop	133
USP1 modulates hepatocellular carcinoma progression via the Hippo/TAZ axis	132
Leveraging glycosylation for early detection and therapeutic target discovery in pancreatic cancer	132
ER-mitochondria association negatively affects wound healing by regulating NLRP3 activation	131
Single-cell sequencing resolves the landscape of immune cells and regulatory mechanisms in HIV-infected immune non-responders	130
The role of SPATA2 in TNF signaling, cancer, and spermatogenesis	128
NEDD4L binds the proteasome and promotes autophagy and bortezomib sensitivity in multiple myeloma	127
ATF4/CEMIP/PKCα promotes anoikis resistance by enhancing protective autophagy in prostate cancer cells	125
METTL16 controls Kaposi’s sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle	123
Ferroptotic MSCs protect mice against sepsis via promoting macrophage efferocytosis	122
IL-17A injury to retinal ganglion cells is mediated by retinal Müller cells in diabetic retinopathy	122
Elaiophylin reduces body weight and lowers glucose levels in obese mice by activating AMPK	119
Enhancing cell death in B-cell malignancies through targeted inhibition of Bcl-3	116
DNAJA4 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma via PSMD2-mediated MYH9 degradation	115
PAF1 cooperates with YAP1 in metaplastic ducts to promote pancreatic cancer	114
Genetic alterations of Keap1 confers chemotherapeutic resistance through functional activation of Nrf2 and Notch pathway in head and neck squamous cell carcinoma	114
In vivo self-assembly and delivery of VEGFR2 siRNA-encapsulated small extracellular vesicles for lung metastatic osteosarcoma therapy	113
Correction: NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation	113
Phosphorylation of USP33 by CDK1 stabilizes the mTORC2 component SIN1	112
UPF1 contributes to the maintenance of endometrial cancer stem cell phenotype by stabilizing LINC00963	111
GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila	110
Underlying mechanisms of glucocorticoid-induced β-cell death and dysfunction: a new role for glycogen synthase kinase 3	107
Hypoxia-responsive circRNAs: A novel but important participant in non-coding RNAs ushered toward tumor hypoxia	107
ZC3H13 mediates N6-methyladenosine modification of SNTB1 to promote epithelial-mesenchymal transition in gastric cancer	106
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC	105
Multi-omics prediction of axillary treatment response and tumour microenvironment alterations in lymph node-positive luminal breast cancer	105
MAGI3 enhances sensitivity to sunitinib in renal cell carcinoma by suppressing the MAS/ERK axis and serves as a prognostic marker	104
PPFIBP1 induces glioma cell migration and invasion through FAK/Src/JNK signaling pathway	104
RNA helicase DDX5 modulates sorafenib sensitivity in hepatocellular carcinoma via the Wnt/β-catenin–ferroptosis axis	104
TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway	103
BRISC is required for optimal activation of NF-κB in Kupffer cells induced by LPS and contributes to acute liver injury	100
Functional delivery of lncRNA TUG1 by endothelial progenitor cells derived extracellular vesicles confers anti-inflammatory macrophage polarization in sepsis via impairing miR-9-5p-targeted SIRT1 inhi	99
Nuclear factor I-C disrupts cellular homeostasis between autophagy and apoptosis via miR-200b-Ambra1 in neural tube defects	98
Tripartite motif 25 ameliorates doxorubicin-induced cardiotoxicity by degrading p85α	96
FTO/IGF2BP2-mediated N6 methyladenosine modification in invasion and metastasis of thyroid carcinoma via CDH12	96
Mitochondrial Drp1 recognizes and induces excessive mPTP opening after hypoxia through BAX-PiC and LRRK2-HK2	96
Mitochondria-derived H2O2 triggers liver regeneration via FoxO3a signaling pathway after partial hepatectomy in mice	96
Knockdown of Porf-2 restores visual function after optic nerve crush injury	95

JUND/linc00976 promotes cholangiocarcinoma progression and metastasis, inhibits ferroptosis by regulating the miR-3202/GPX4 axis	95
PRMT1 methylation of WTAP promotes multiple myeloma tumorigenesis by activating oxidative phosphorylation via m6A modification of NDUFS6	94
IGFBP2/ITGA5 promotes gefitinib resistance via activating STAT3/CXCL1 axis in non-small cell lung cancer	94
Migration deficits of the neural crest caused by CXADR triplication in a human Down syndrome stem cell model	92
LAPTM4B-mediated hepatocellular carcinoma stem cell proliferation and MDSC migration: implications for HCC progression and sensitivity to PD-L1 monoclonal antibody therapy	92
CAR-T therapy dilemma and innovative design strategies for next generation	90
Therapeutic role of PTEN in tissue regeneration for management of neurological disorders: stem cell behaviors to an in-depth review	88
The tyrosine-kinase inhibitor Nintedanib ameliorates autosomal-dominant polycystic kidney disease	87
LINC00152 induced by TGF-β promotes metastasis via HuR in lung adenocarcinoma	87
m5C-dependent cross-regulation between nuclear reader ALYREF and writer NSUN2 promotes urothelial bladder cancer malignancy through facilitating RABL6/TK1 mRNAs splicing and stabilization	86
Preservation of retinal structure and function in two mouse models of inherited retinal degeneration by ONL1204, an inhibitor of the Fas receptor	85
Aryl hydrocarbon receptor dependent anti-inflammation and neuroprotective effects of tryptophan metabolites on retinal ischemia/reperfusion injury	85
USP11-mediated LSH deubiquitination inhibits ferroptosis in colorectal cancer through epigenetic activation of CYP24A1	84
The multifaceted role of Fragile X-Related Protein 1 (FXR1) in cellular processes: an updated review on cancer and clinical applications	84
Glucose deprivation triggers DCAF1-mediated inactivation of Rheb-mTORC1 and promotes cancer cell survival	84
An integrated bioinformatic investigation of mitochondrial solute carrier family 25 (SLC25) in colon cancer followed by preliminary validation of member 5 (SLC25A5) in tumorigenesis	83
m6A and m5C modification of GPX4 facilitates anticancer immunity via STING activation	83
miR-28-based combination therapy impairs aggressive B cell lymphoma growth by rewiring DNA replication	83
FAK mediates LPS-induced inflammatory lung injury through interacting TAK1 and activating TAK1-NFκB pathway	81
GBA1-dependent membrane glucosylceramide reprogramming promotes liver cancer metastasis via activation of the Wnt/β-catenin signalling pathway	80
Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1	79
CYP1B1 inhibits ferroptosis and induces anti-PD-1 resistance by degrading ACSL4 in colorectal cancer	79
Targeting FAM111B attenuates mitophagy and increases the sensitivity to lenvatinib treatment by increasing MFN2 stability in hepatocellular carcinoma	79
The regulation, function, and role of lipophagy, a form of selective autophagy, in metabolic disorders	79
Pivotal role of IL-8 derived from the interaction between osteosarcoma and tumor-associated macrophages in osteosarcoma growth and metastasis via the FAK pathway	78
Macrophages downregulate NEDD9 to counteract S. Typhimurium- mediated FAK-AKT activation and lysosome inhibition	77
KDM1A epigenetically enhances RAD51 expression to suppress the STING-associated anti-tumor immunity in esophageal squamous cell carcinoma	77
Radiotherapy remodels the tumor microenvironment for enhancing immunotherapeutic sensitivity	77
SerpinB7 deficiency contributes to development of psoriasis via calcium-mediated keratinocyte differentiation dysfunction	76
Apatinib inhibits glioma cell malignancy in patient-derived orthotopic xenograft mouse model by targeting thrombospondin 1/myosin heavy chain 9 axis	76
SOX4-BMI1 axis promotes non-small cell lung cancer progression and facilitates angiogenesis by suppressing ZNF24	75
METTL3-mediated m6A modification of LINC00839 maintains glioma stem cells and radiation resistance by activating Wnt/β-catenin signaling	74
MESH1 knockdown triggers proliferation arrest through TAZ repression	74
Identification of multiple organ metastasis-associated hub mRNA/miRNA signatures in non-small cell lung cancer	74
RNF115/BCA2 deficiency alleviated acute liver injury in mice by promoting autophagy and inhibiting inflammatory response	74
CD36 aggravates podocyte injury by activating NLRP3 inflammasome and inhibiting autophagy in lupus nephritis	73
A novel protein encoded by circUBE4B promotes progression of esophageal squamous cell carcinoma by augmenting MAPK/ERK signaling	73
A novel inhibitor of the mitochondrial respiratory complex I with uncoupling properties exerts potent antitumor activity	73
BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma	73
Tulp1 deficiency causes early-onset retinal degeneration through affecting ciliogenesis and activating ferroptosis in zebrafish	72
Regulatory T cells in skeletal muscle repair and regeneration: recent insights	72
Opposing roles for GSK3β and ERK1-dependent phosphorylation of huntingtin during neuronal dysfunction and cell death in Huntington’s disease	71
CD146 regulates the stemness and chemoresistance of hepatocellular carcinoma via JAG2-NOTCH signaling	71
Pharmacological inhibition of Ref-1 enhances the therapeutic sensitivity of papillary thyroid carcinoma to vemurafenib	71
Genome-wide identification of microRNA targets reveals positive regulation of the Hippo pathway by miR-122 during liver development	70
Correction to: Tumor-associated macrophage-derived exosomes transmitting miR-193a-5p promote the progression of renal cell carcinoma via TIMP2-dependent vasculogenic mimicry	70
Downregulation of TPX2 impairs the antitumor activity of CD8+ T cells in hepatocellular carcinoma	70
Inhibitory role of proguanil on the growth of bladder cancer via enhancing EGFR degradation and inhibiting its downstream signaling pathway to induce autophagy	70
Deficiency of PPP6C protects TNF-induced necroptosis through activation of TAK1	68
High dose androgen suppresses natural killer cytotoxicity of castration-resistant prostate cancer cells via altering AR/circFKBP5/miRNA-513a-5p/PD-L1 signals	68
MiR-122-5p regulates the mevalonate pathway by targeting p53 in non-small cell lung cancer	67
Selective degradation of AR-V7 to overcome castration resistance of prostate cancer	66
A novel function of STAT3β in suppressing interferon response improves outcome in acute myeloid leukemia	65
Angiotensin II related glial cell activation and necroptosis of retinal ganglion cells after systemic hypotension in glaucoma	64
BNIP3 (BCL2 interacting protein 3) regulates pluripotency by modulating mitochondrial homeostasis via mitophagy	64
DDX5 deficiency drives non-canonical NF-κB activation and NRF2 expression, influencing sorafenib response and hepatocellular carcinoma progression	64
MicroRNA miR-1275 coordinately regulates AEA/LPA signals via targeting FAAH in lipid metabolism reprogramming of gastric cancer	64
Nek2A prevents centrosome clustering and induces cell death in cancer cells via KIF2C interaction	64
SMOC2 promotes an epithelial-mesenchymal transition and a pro-metastatic phenotype in epithelial cells of renal cell carcinoma origin	64
β‐arrestin 2 negatively regulates lung cancer progression by inhibiting the TRAF6 signaling axis for NF-κB activation and autophagy induced by TLR3 and TLR4	64
Trim21-mediated CCT2 ubiquitination suppresses malignant progression and promotes CD4+T cell activation in breast cancer	64
Tim-3+ decidual Mφs induced Th2 and Treg bias in decidual CD4+T cells and promoted pregnancy maintenance via CD132	64
Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans	63
USP7 promotes temozolomide resistance by stabilizing MGMT in glioblastoma	63
The kinase activity of integrin-linked kinase regulates cellular senescence in gastric cancer	63
MLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL10	63
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer	63
Aldolase B-driven lactagenesis and CEACAM6 activation promote cell renewal and chemoresistance in colorectal cancer through the Warburg effect	62
Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer’s disease	62
Circulating miR-184 is a potential predictive biomarker of cardiac damage in Anderson–Fabry disease	62
The mitochondrial ATP-dependent potassium channel (mitoKATP) controls skeletal muscle structure and function	62
STING dependent BAX-IRF3 signaling results in apoptosis during late-stage Coxiella burnetii infection	62
Nitroglycerin: a comprehensive review in cancer therapy	61
Glycolysis-related lncRNA TMEM105 upregulates LDHA to facilitate breast cancer liver metastasis via sponging miR-1208	61
S1PR3-driven positive feedback loop sustains STAT3 activation and keratinocyte hyperproliferation in psoriasis	61
TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC4	60
Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia	60
Chemotoxicity-induced exosomal lncFERO regulates ferroptosis and stemness in gastric cancer stem cells	60
Hepatocyte DDX3X protects against drug-induced acute liver injury via controlling stress granule formation and oxidative stress	60
Correction: MicroRNA-29a induces loss of 5-hydroxymethylcytosine and promotes metastasis of hepatocellular carcinoma through a TET–SOCS1–MMP9 signaling axis	60

SUMOylation of PDPK1 Is required to maintain glycolysis-dependent CD4 T-cell homeostasis	60
Protein kinase G inhibition preserves photoreceptor viability and function in a new mouse model for autosomal dominant retinitis pigmentosa	60
TAB182 aggravates progression of esophageal squamous cell carcinoma by enhancing β-catenin nuclear translocation through FHL2 dependent manner	60
Wet-dry-wet drug screen leads to the synthesis of TS1, a novel compound reversing lung fibrosis through inhibition of myofibroblast differentiation	59
Retraction Note: Long noncoding RNA LINC01234 promotes serine hydroxymethyltransferase 2 expression and proliferation by competitively binding miR-642a-5p in colon cancer	59
Germline specific genes increase DNA double-strand break repair and radioresistance in lung adenocarcinoma cells	59
Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss	59
Retraction Note: Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer	59
MLK4 regulates DNA damage response and promotes triple-negative breast cancer chemoresistance	59
Reduced protection of RIPK3-deficient mice against influenza by matrix protein 2 ectodomain targeted active and passive vaccination strategies	59
Balancing the functions of DNA extracellular traps in intracellular parasite infections: implications for host defense, disease pathology and therapy	58
Novel roles of luteinizing hormone (LH) in tissue regeneration-associated functions in endometrial stem cells	58
YAP1 facilitates the pathogenesis of psoriasis via modulating keratinocyte proliferation and inflammation	58
Card9 protects sepsis by regulating Ripk2-mediated activation of NLRP3 inflammasome in macrophages	57
Correction to: Deubiquitylase OTUD6B stabilizes the mutated pVHL and suppresses cell migration in clear cell renal cell carcinoma	57
SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice	57
Loss of RNF41 promotes bladder cancer metastasis through increasing NUDC stability to enhance tubulin polymerization	57
Repurposing MDM2 inhibitor RG7388 for TP53-mutant NSCLC: a p53-independent pyroptotic mechanism via ROS/p-p38/NOXA/caspase-3/GSDME axis	56
LncRNA SNHG1 regulates neuroblastoma cell fate via interactions with HDAC1/2	56
Galectin-3 promotes secretion of proteases that decrease epithelium integrity in human colon cancer cells	56
Transglutaminase 2 associated with PI3K and PTEN in a membrane-bound signalosome platform blunts cell death	56
A novel Hoxd13 mutation causes synpolydactyly and promotes osteoclast differentiation by regulating pSmad5/p65/c-Fos/Rank axis	56
Innate and adaptive immune cell interaction drives inflammasome activation and hepatocyte apoptosis in murine liver injury from immune checkpoint inhibitors	56
NAT10 mediates TLR2 to promote podocyte senescence in adriamycin-induced nephropathy	56
TNFAIP2 promotes HIF1α transcription and breast cancer angiogenesis by activating the Rac1-ERK-AP1 signaling axis	56
Histone methyltransferase Smyd2 drives adipogenesis via regulating STAT3 phosphorylation	55
USP14/S100A11 axis promote colorectal cancer progression by inhibiting cell senescence	55
p21-activated kinase 4 controls the aggregation of α-synuclein by reducing the monomeric and aggregated forms of α-synuclein: involvement of the E3 ubiquitin ligase NEDD4-1	55
Critical analysis of translational potential of rodent models of white matter pathology across a wide spectrum of human diseases	55
PRMT1-mediated methylation of UBE2m promoting calcium oxalate crystal-induced kidney injury by inhibiting fatty acid metabolism	55
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway	55
The feedback loop between MTA1 and MTA3/TRIM21 modulates stemness of breast cancer in response to estrogen	55
Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2 recruitment onto mitochondria and PARK2-PARK6 activity during mitophagy	55
Retraction Note to: Expansion of monocytic myeloid-derived suppressor cells ameliorated intestinal inflammatory response by radiation through SOCS3 expression	55
A positive feedback loop of lncRNA-RMRP/ZNRF3 axis and Wnt/β-catenin signaling regulates the progression and temozolomide resistance in glioma	54
Downregulated liver-elevated long intergenic noncoding RNA (LINC02428) is a tumor suppressor that blocks KDM5B/IGF2BP1 positive feedback loop in hepatocellular carcinoma	54
Nuclear pore protein POM121 regulates subcellular localization and transcriptional activity of PPARγ	54
RIPK3 promoter hypermethylation in hepatocytes protects from bile acid-induced inflammation and necroptosis	54
TRIM26 deficiency enhancing liver regeneration through macrophage polarization and β-catenin pathway activation	54
Transcription factor EB-mediated mesenchymal stem cell therapy induces autophagy and alleviates spinocerebellar ataxia type 3 defects in neuronal cells model	53
O-GlcNAcylation inhibition redirects the response of colon cancer cells to chemotherapy from senescence to apoptosis	53
Alpha-Synuclein defects autophagy by impairing SNAP29-mediated autophagosome-lysosome fusion	53
Exosomes derived from mesenchymal stem cells in diabetes and diabetic complications	53
The role of vitamin K and its antagonist in the process of ferroptosis-damaged RPE-mediated CNV	53
GSDMD-dependent neutrophil extracellular traps promote macrophage-to-myofibroblast transition and renal fibrosis in obstructive nephropathy	53
Nerve growth factor promotes lysyl oxidase-dependent chondrosarcoma cell metastasis by suppressing miR-149-5p synthesis	53
Stanniocalcin 1 promotes lung metastasis of breast cancer by enhancing EGFR–ERK–S100A4 signaling	53
Exosomal circTGFBR2 promotes hepatocellular carcinoma progression via enhancing ATG5 mediated protective autophagy	52
SAP130 released by damaged tubule drives necroinflammation via miRNA-219c/Mincle signaling in acute kidney injury	52
Role of cardiolipins, mitochondria, and autophagy in the differentiation process activated by all-trans retinoic acid in acute promyelocytic leukemia	52
LncRNA FIRRE functions as a tumor promoter by interaction with PTBP1 to stabilize BECN1 mRNA and facilitate autophagy	52
CircNEIL3 mediates pyroptosis to influence lung adenocarcinoma radiotherapy by upregulating PIF1 through miR-1184 inhibition	52
Metabolic gatekeepers: harnessing tumor-derived metabolites to optimize T cell-based immunotherapy efficacy in the tumor microenvironment	52
Androgen-targeted hsa_circ_0085121 encodes a novel protein and improves the development of prostate cancer through facilitating the activity of PI3K/Akt/mTOR pathway and enhancing AR-V7 alternative sp	52
Systemic mechanisms of necrotic cell debris clearance	52
TNFAIP8 protein functions as a tumor suppressor in inflammation-associated colorectal tumorigenesis	51
Tumor-associated macrophage-derived exosomes transmitting miR-193a-5p promote the progression of renal cell carcinoma via TIMP2-dependent vasculogenic mimicry	51
GATA4 regulates the transcription of MMP9 to suppress the invasion and migration of breast cancer cells via HDAC1-mediated p65 deacetylation	51
Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis	51
Generation of functional neurons from adult human mucosal olfactory ensheathing glia by direct lineage conversion	51
Targeting metabolic vulnerability by combining NAMPT inhibitors and disulfiram for treatment of recurrent ovarian cancer	51
Transcriptome reprogramming of Epstein-Barr virus infected epithelial and B cells reveals distinct host-virus interaction profiles	51
PAK6 rescues pathogenic LRRK2-mediated ciliogenesis and centrosomal cohesion defects in a mutation-specific manner	51
TGF-β-induced PLEK2 promotes metastasis and chemoresistance in oesophageal squamous cell carcinoma by regulating LCN2	51
Correction: SETD8 inhibits apoptosis and ferroptosis of Ewing’s sarcoma through YBX1/RAC3 axis	51
Ascitic fluid shear stress in concert with hepatocyte growth factor drive stemness and chemoresistance of ovarian cancer cells via the c-Met-PI3K/Akt-miR-199a-3p signaling pathway	51
Retraction Note: Identification of protein kinase inhibitors to reprogram breast cancer cells	50
WWC1/2 regulate spinogenesis and cognition in mice by stabilizing AMOT	50
CPAP enhances and maintains chronic inflammation in hepatocytes to promote hepatocarcinogenesis	50
Selective deletion of E3 ubiquitin ligase FBW7 in VE-cadherin-positive cells instigates diffuse large B-cell lymphoma in mice in vivo	50
The role of circular RNAs in regulating resistance to cancer immunotherapy: mechanisms and implications	50
Correction to: ONECUT2 facilitates hepatocellular carcinoma metastasis by transcriptionally upregulating FGF2 and ACLY	50
Mechanistic insights into SIRT7 and EZH2 regulation of cisplatin resistance in bladder cancer cells	50
LncRNA-MIAT promotes thyroid cancer progression and function as ceRNA to target EZH2 by sponging miR-150-5p	50
Inhibition of the immunoproteasome modulates innate immunity to ameliorate muscle pathology of dysferlin-deficient BlAJ mice	50
Correction to: Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells	50
RBM4 regulates cellular senescence via miR1244/SERPINE1 axis	49
AURKAIP1 actuates tumor progression through stabilizing DDX5 in triple negative breast cancer	49
Retraction Note: RUNX3-regulated circRNA METTL3 inhibits colorectal cancer proliferation and metastasis via miR-107/PER3 axis	49
Suppression of lncRNA NLRP3 inhibits NLRP3-triggered inflammatory responses in early acute lung injury	49
ETS-1-activated LINC01016 over-expression promotes tumor progression via suppression of RFFL-mediated DHX9 ubiquitination degradation in breast cancers	49
Bone marrow-independent adventitial macrophage progenitor cells contribute to angiogenesis	49
Retraction Note: Involvement of autophagy in hypoxia-BNIP3 signaling to promote epidermal keratinocyte migration	49
Versatile enhancement of the killing potential of anti-cancer agents achieved by peptide mimetics of the PCNA interface towards specialized DNA polymerases	49
Transglutaminase 2 function in glioblastoma tumor efferocytosis	49
Correction: Tumor-educated B cells promote renal cancer metastasis via inducing the IL-1β/HIF-2α/Notch1 signals	49
nNOS in Erbb4-positive neurons regulates GABAergic transmission in mouse hippocampus	48
SNHG25 facilitates SNORA50C accumulation to stabilize HDAC1 in neuroblastoma cells	48
Non-canonical functions of spliceosome components in cancer progression	48
Claudin-7 is essential for the maintenance of colonic stem cell homoeostasis via the modulation of Wnt/Notch signalling	48
Endothelial cell-derived RSPO3 activates Gαi1/3-Erk signaling and protects neurons from ischemia/reperfusion injury	48
Deficiency of SIAH1 promotes the formation of filopodia by increasing the accumulation of FASN in liver cancer	48
LMO2 promotes the development of AML through interaction with transcription co-regulator LDB1	48
MiR-1246b, a novel miRNA molecule of extracellular vesicles in bronchoalveolar lavage fluid, promotes nodule growth through FGF14 in patients with lung cancer	48
The YTHDC1 reader protein recognizes and regulates the lncRNA MEG3 following its METTL3-mediated m6A methylation: a novel mechanism early during radiation-induced liver injury	48