Chemical Science

Article	Citations
Beyond diffusion: ion and electron migration contribute to charge transport in redox-conducting metal–organic frameworks	208
Back cover	203
Front cover	202
Contents list	179
Accelerating the end-to-end production of cyclic phosphate monomers with modular flow chemistry	171
De novogeneration of a bright blue fluorophore from 2-oxoglutarate in biological samples	165
With or without a co-solvent? highly efficient ultrafast phenanthrenequinone-electron rich alkene (PQ-ERA) photoclick reactions	152
Photochemical H2 activation by an Zn–Fe heterometallic: a mechanistic investigation	147
Syntheses, homeomorphic and configurational isomerizations, and structures of macrocyclic aliphatic dibridgehead diphosphines; molecules that turn themselves inside out	144
Enantioselective nickel-catalyzed Mizoroki–Heck cyclizations of amide electrophiles	143
Inter-layer magnetic tuning by gas adsorption in π-stacked pillared-layer framework magnets	142
Isostructural bridging diferrous chalcogenide cores [FeII(μ-E)FeII] (E = O, S, Se, Te) with decreasing antiferromagnetic coupling down the chalcogenide series	142
RAFT step-growth polymerization via the Z-group approach and deconstruction by RAFT interchange	138
Correction: Structural tuning of organoruthenium compounds allows oxidative switch to control ER stress pathways and bypass multidrug resistance	137
Correction: Multi-stimuli programmable FRET based RGB absorbing antennae towards ratiometric temperature, pH and multiple metal ion sensing	135
Correction: When SF5 outplays CF3: effects of pentafluorosulfanyl decorated scorpionates on copper	134
Correction: Magnetic coupling between Fe(NO) spin probe ligands through diamagnetic NiII, PdII and PtII tetrathiolate bridges	133
Intramolecular-locking modification enables efficient asymmetric donor–acceptor–donor′ type ultraviolet emitters for high-performance OLEDs with reduced efficiency roll-off and high color purity	127
Probing the water adsorption and stability under steam flow of Zr-based metal–organic frameworks using 91Zr solid-state NMR spectroscopy	125
Proton transfer induced excited-state aromaticity gain for chromophores with maximal Stokes shifts	120
Revisiting the reaction pathways for phospholipid hydrolysis catalyzed by phospholipase A2 with QM/MM methods	119
A free boratriptycene-type Lewis superacid	118
18F-Labeled brain-penetrant EGFR tyrosine kinase inhibitors for PET imaging of glioblastoma	115
Deconvoluting binding sites in amyloid nanofibrils using time-resolved spectroscopy	114
Time-resolved circular dichroism of excitonic systems: theory and experiment on an exemplary squaraine polymer	113

Multifaceted nucleic acid probing with a rationally upgraded molecular rotor	112
Probing substrate binding inside a paramagnetic cavity: a NMR spectroscopy toolbox for combined experimental and theoretical investigation	108
Competing dynamics of intramolecular deactivation and bimolecular charge transfer processes in luminescent Fe(iii) N-heterocyclic carbene complexes	108
Three-dimensional structural alignment based discovery and molecular basis of AtoB, catalyzing linear tetracyclic formation	107
Ultra-long cycle sodium ion batteries enabled by the glutaric anhydride additive	106
Back cover	105
Correction: FragGen: towards 3D geometry reliable fragment-based molecular generation	105
Beyond chemical structures: lessons and guiding principles for the next generation of molecular databases	105
Engineering mechanisms of proton-coupled electron transfer to a titanium-substituted polyoxovanadate–alkoxide	104
Self-sensitized Cu(ii)-complex catalyzed solar driven CO2 reduction	101
Front cover	98
Visible light-driven dearomative ring expansion of (aza)arenes to access dihydrofuran-based polycyclic compounds	98
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Inside front cover	95
Contents list	94
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Arresting dissolution of two-dimensional metal–organic frameworks enables long life in electrochemical devices	89
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Contents list	86
Front cover	84
Back cover	84
A reversible plasmonic nanoprobe for dynamic imaging of intracellular pH during endocytosis	83
Inside front cover	83
Mechanism and dynamics of photoswitchable flavoprotein charge-transfer complexes	82
Identification of metal-centered excited states in Cr(iii) complexes with time-resolved L-edge X-ray spectroscopy	82
Inside front cover	82
Deciphering the mechanism of hydrogen peroxide formation in ultrasound-mediated water-in-oil microdroplets	82
Isothiourea-catalysed enantioselective synthesis of phosphonate-functionalised β-lactones	81
Biosynthesis of pleuromutilin congeners using an Aspergillus oryzae expression platform	81
Catalytic asymmetric hydrometallation of cyclobutenes with salicylaldehydes	81
Leveraging heterocycle-fused 1,4-benzoquinone to design chemical modulators for both metal-free and metal-bound amyloid-β	80
Molecular engineering of 1D conjugated copper anilate coordination polymers for boosting electrocatalytic nitrate reduction to ammonia	80
A biocompatible hydrogel as a template for oxidative decomposition reactions: a chemodosimetric analysis and in vitro imaging of hypochlorite	80
Affinity-based protein profiling of MDM2 inhibitor Navtemadlin	80
Modulatory spin-flip of triplet excitons via diversiform electron-donating units for MR-TADF emitters towards solution-processed narrowband OLEDs	79
Light-controlled enzymatic synthesis of γ-CD using a recyclable azobenzene template	79
Bucking the trend: understanding lipopolysaccharide structure and outer membrane dynamics in cold-adapted Pseudomonas isolated from Enigma Lake, Antarctica	78
Isoacridone dyes with parallel reactivity from both singlet and triplet excited states for biphotonic catalysis and upconversion	78
MR-TADF liquid crystals: towards self assembling host–guest mixtures showing narrowband emission from the mesophase	77
Synthesis of functionalised isochromans: epoxides as aldehyde surrogates in hexafluoroisopropanol	75
Hydroalkylation of styrenes enabled by boryl radical mediated halogen atom transfer	74
Retaining the structural integrity of disulfide bonds in diphtheria toxoid carrier protein is crucial for the effectiveness of glycoconjugate vaccine candidates	74
Tuning through-space interactions via the secondary coordination sphere of an artificial metalloenzyme leads to enhanced Rh(iii)-catalysis	74
Facile preparation of sulfonium peptide and protein probes for selective crosslinking of methyllysine readers	73
Biocatalytic reductive amination as a route to isotopically labelled amino acids suitable for analysis of large proteins by NMR	73
Molecularly engineered AIEgens with enhanced quantum and singlet-oxygen yield for mitochondria-targeted imaging and photodynamic therapy	72

LnDOTA puppeteering: removing the water molecule and imposing tetragonal symmetry	72
A pair of conjoined trinuclear sub-frameworks in a pentanuclear double-cavity discrete coordination cage	72
Therapeutic efficacy of 211At-radiolabeled 2,6-diisopropylphenyl azide in mouse models of human lung cancer	71
Unified ionic and radical C-4 alkylation and arylation of pyridines	71
Negative cooperativity in the formation of H-bond networks involving primary anilines	71
Gaining control on optical force by the stimulated-emission resonance effect	70
A silylboronate-mediated strategy for cross-coupling of alkyl fluorides with aryl alkanes: mechanistic insights and scope expansion	70
Facile modification of phosphole-based aggregation-induced emission luminogens with sulfonyl isocyanates	70
A method to identify small molecule/protein pairs susceptible to protein ubiquitination by the CRBN E3 ligase	69
Sequence-dependent conformational transitions of disordered proteins during condensation	69
MnO2 nanosheets as a carrier and accelerator for improved live-cell biosensing application of CRISPR/Cas12a	69
Mori generalized master equations offer an efficient route to predict and interpret polaron transport	68
Free-energy decomposition of salt effects on the solubilities of small molecules and the role of excluded-volume effects	68
Polarization-induced nanohelixes of organic cocrystals from asymmetric components with dopant-induced chirality inversion	68
Mechanochemically-induced glass formation from two-dimensional hybrid organic–inorganic perovskites	68
Intramolecular CH⋯π attraction mediated conformational polymorphism of constrained helical peptides	68
Chiral cobalt(ii) complex-promoted asymmetric para-Claisen rearrangement of allyl α-naphthol ethers	67
Revealing the nature of covalently tethered distonic radical anions in the generation of heteroatom-centered radicals: evidence for the polarity-matching PCET pathway	67
Curved graphene nanoribbons derived from tetrahydropyrene-based polyphenylenesviaone-pot K-region oxidation and Scholl cyclization	67
Applications of metal–organic framework-based bioelectrodes	67
A constitutional isomer selective chemical proteomic strategy for system-wide profiling of protein lysine 5-hydroxylation	67
Polymerization-induced self-assembly enables access to diverse highly ordered structures through kinetic and thermodynamic pathways	66
How do donor and acceptor substituents change the photophysical and photochemical behavior of dithienylethenes? The search for a water-soluble visible-light photoswitch	66
Light-induced twisting, untwisting, and retwisting of aromatic polyamides: an interplay between the induced chirality and the co-facial π-stacking interactions	65
Metalation-induced denitrogenative reductive coupling of isocyanides on a silylene-bridged nickel cluster	65
[2 + 2] cycloaddition and its photomechanical effects on 1D coordination polymers with reversible amide bonds and coordination site regulation	65
Discovery strategy leads to the first melt-castable cocrystal based on an energetic oxidizing salt	65
Molybdenum carbonyl assisted reductive tetramerization of CO by activated magnesium(i) compounds: squarate dianion vs. metallo-ketene formation	65
Effect of cyclic topology versus linear terpolymers on antibacterial activity and biocompatibility: antimicrobial peptide avatars	64
Front cover	64
Mechanism of action and evaluation of ratiometric probes for uric acid using lanthanide complexes with tetraazatriphenylene sensitisers	64
Ultrafast and selective labeling of endogenous proteins using affinity-based benzotriazole chemistry	63
Non-covalent reconfigurable microgel colloidosomes with a well-defined bilayer shell	62
More π, please: What drives the formation of unsaturated molecules in the interstellar medium?	62
(3 + 2)-Cycloaddition of bicyclobutanes and thioketones: access to 2-thiabicyclo[2.1.1]hexanes without the use of catalysts or light	62
“Mn-locking” effect by anionic coordination manipulation stabilizing Mn-rich phosphate cathodes	61
A J-aggregated nanoporphyrin overcoming phototoxic side effects in superior phototherapy with two-pronged effects	61
Understanding nascent plasmons and metallic bonding in atomically precise gold nanoclusters	61
Influence of the Pt/ionomer/water interface on the oxygen reduction reaction: insights into the micro-three-phase interface	61
RGB tri-luminescence in organic–inorganic zirconium halide perovskites	60
Development of 8–17 XNAzymes that are functional in cells	60
Catalysis of a LiF-rich SEI by aromatic structure modified porous polyamine for stable all-solid-state lithium metal batteries	59
State-of-the-art accounts of hyperpolarized 15N-labeled molecular imaging probes for magnetic resonance spectroscopy and imaging	59
Rational design of circularly polarized luminescence active chiral metal–organic frameworks for logic devices	59
An AND-gate bioluminescent probe for precise tumor imaging	58
Characterization of a LanC-free pathway for the formation of an ll-MeLan residue and an alloAviMeCys residue in the newly identified class V lanthipeptide triantimycins	58
Molecular cyclo-P3 complexes of the rare-earth elements via a one-pot reaction and selective reduction	58
Controlled, one-pot synthesis of recyclable poly(1,3-diene)-polyester block copolymers, catalyzed by yttrium β-diketiminate complexes	58
Ni-catalyzed asymmetric hydrophosphinylation of conjugated enynes and mechanistic studies	58
Spectroscopic application of few-femtosecond deep-ultraviolet laser pulses from resonant dispersive wave emission in a hollow capillary fibre	58
A general strategy to the intracellular sensing of glycosidases using AIE-based glycoclusters	57
In silico screening of LRRK2 WDR domain inhibitors using deep docking and free energy simulations	57
Origin of low melting point of ionic liquids: dominant role of entropy	57
Simultaneously enhancing the planarity and electron-donating capability of donors for through-space charge transfer TADF towards deep-red emission	56
Structure–function relationships in pure archaeal bipolar tetraether lipids	56
Luminescent carbene–copper(i)–amide polymers for efficient host-free solution-processed OLEDs	56
The supersaturation perspective on the amyloid hypothesis	56
Excitation generated preferential binding sites for ethane on porous carbon–copper porphyrin sorbents: ethane/ethylene adsorptive separation improved by light	56
Reactivity of 1,3-enyne MIDA boronates: exploration of novel 1,2-alkyne shift via gem-difluorination	56
Enhanced N-directed electrophilic C–H borylation generates BN–[5]- and [6]helicenes with improved photophysical properties	56
Defect-engineered surfaces to investigate the formation of self-assembled molecular networks	55
Orbital electron delocalization of axial-coordinated modified FeN4 and structurally ordered PtFe intermetallic synergistically for efficient oxygen reduction reaction catalysis	55
Spin polarized electron dynamics enhance water splitting efficiency by yttrium iron garnet photoanodes: a new platform for spin selective photocatalysis	55
Molecular brush-based ultrathin polymer electrolytes with stable interfaces for high-voltage large-areal-capacity lithium metal batteries	55
In situ modification of the d-band in the core–shell structure for efficient hydrogen storage via electrocatalytic N2 fixation	55
Reducing the internal reorganization energy via symmetry controlled π-electron delocalization	55
Electrochemical hydrogenative coupling of nitrobenzene into azobenzene over a mesoporous palladium–sulfur cathode	54
Visible-light-induced organocatalytic enantioselective N–H insertion of α-diazoesters enabled by indirect free carbene capture	54
Bromine radical release from a nickel-complex facilitates the activation of alkyl boronic acids: a boron selective Suzuki–Miyaura cross coupling	54
Site-specific doping of silver atoms into a Au25 nanocluster as directed by ligand binding preferences	54
Photochemical synthesis of carbazole-fused Blatter radicals: Effective spin injection to the carbazole system	54
De novo synthesis of inherently chiral heteracalix[4]aromatics from enantioselective macrocyclization enabled by chiral phosphoric acid-catalyzed intramolecular SNAr reaction	54
Substituent effects on paratropicity and diatropicity in π-extended hexapyrrolohexaazacoronene	53
Transcriptome-wide identification of single-stranded RNA binding proteins	53
Strain-enabled radical spirocyclization cascades: rapid access to spirocyclobutyl lactones and – lactams	53
Photolysis-driven bond activation by thorium and uranium tetraosmate polyhydride complexes	53
Mechanisms of controlled stabilizer-free synthesis of gold nanoparticles in liquid aerosol containing plasma	52
Formal synthesis of kibdelomycin and derivatisation of amycolose glycosides	52
A photoinduced transient activating strategy for late-stage chemoselective C(sp3)–H trifluoromethylation of azines	52
Ambipolar conjugated ladder polymers by room-temperature Knoevenagel polymerization	52

Cold-catalytic antitumor immunity with pyroelectric black phosphorus nanosheets	52
Acridine photocatalysis enables tricomponent direct decarboxylative amine construction	52
Two-sided asymmetric nanofluidic membrane for enhanced ion transport and osmotic energy harvesting	51
109Ag NMR chemical shift as a descriptor for Brønsted acidity from molecules to materials	51
Evolutionary adaptation from hydrolytic to oxygenolytic catalysis at the α/β-hydrolase fold	51
Drop-cast gold nanoparticles are not always electrocatalytically active for the borohydride oxidation reaction	51
Chemiluminescent duplex analysis using phenoxy-1,2-dioxetane luminophores with color modulation	51
Visible-light-initiated metal-free Csp3–Csp3 to Csp3–N conversion in homobenzylic sulfonamides with N-iodoimides	51
Dynamic handedness inversion of self-organized helical superstructures enabled by novel thermally stable light-driven chiral hydrazone switches	50
Unraveling the local coordination effect of Cu–N–C single-atom catalysts towards CO adsorption via a gas-phase cluster model approach	50
Guiding catalytic CO2 reduction to ethanol with copper grain boundaries	50
Planar pentacoordinate s-block metals	50
Deciphering the chemical bonding of the trivalent oxygen atom in oxygen doped graphene	50
Redox-neutral manganese-catalyzed synthesis of 1-pyrrolines	50
Easy access to amphiphilic nitrogenous block copolymers via switchable catalysis	50
First synthesis of RuSn solid-solution alloy nanoparticles and their enhanced hydrogen evolution reaction activity	49
DNP NMR spectroscopy enabled direct characterization of polystyrene-supported catalyst species for synthesis of glycidyl esters by transesterification	49
Direct detection of spin polarization in photoinduced charge transfer through a chiral bridge	49
Efficient helical columnar emitters of chiral homoleptic Pt(ii) metallomesogens for circularly polarized electroluminescence	49
Exploring Au(i) involving halogen bonding with N-heterocyclic carbene Au(i) aryl complexes in crystalline media	49
Augmenting genetic algorithms with machine learning for inverse molecular design	49
pH jump kinetics in colliding microdroplets: accelerated synthesis of azamonardine from dopamine and resorcinol	49
Highly efficient organic long persistent luminescence based on host–guest doping systems	48
Intramolecular photochemical [2 + 1]-cycloadditions of nucleophilic siloxy carbenes	48
Unveiling upsurge of photogenerated ROS: control of intersystem crossing through tuning aggregation patterns	48
Identification of allosteric sites and ligand-induced modulation in the dopamine receptor through large-scale alchemical mutation scan	48
On the use of real-world datasets for reaction yield prediction	48
Synthesis of polysubstituted cyclobutanes through a photoredox strain-release/[3,3]-rearrangement cascade	48
Back cover	47
Engineering the solid electrolyte interphase for enhancing high-rate cycling and temperature adaptability of lithium-ion batteries	47
Front cover	47
Inside front cover	47
Correction: Ion pair extractant selective for LiCl and LiBr	47
High order assembly of multiple protein cages with homogeneous sizes and shapes via limited cage surface engineering	47
Double coordination shell modulation of nitrogen-free atomic manganese sites for enhancing oxygen reduction performance	47
Strategic design of Fe and N co-doped hierarchically porous carbon as superior ORR catalyst: from the perspective of nanoarchitectonics	47
Inside back cover	47
Correction: Site- and stereoselective silver-catalyzed intramolecular amination of electron-deficient heterobenzylic C–H bonds	47
Contents list	47
Catalytic enantioselective synthesis of α-C chiral sulfones enabled by merging photoactive electron donor–acceptor complexes with nickel catalysis	47
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Contents list	46
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Implications of Ga promotion and metal–oxide interface from tailored PtGa propane dehydrogenation catalysts supported on carbon	45
PB and AsB triple bonds in the linear PB2O− and AsB2O− species	45
Front cover	45
Back cover	45
Versatile post-functionalisation strategy for the formation of modular organic–inorganic polyoxometalate hybrids	45
Visualizing the mode of action and supramolecular assembly of teixobactin analogues in Bacillus subtilis	45
Single-molecule-level detection of interfacial molecular structures and ultrafast dynamics	45
Front cover	45
Back cover	45
Shallow and deep trap states of solvated electrons in methanol and their formation, electronic excitation, and relaxation dynamics	45
Enantiomeric β-sheet peptides from Aβ form homochiral pleated β-sheets rather than heterochiral rippled β-sheets	45
Engineering perfluoroarenes for enhanced molecular barrier effect and chirality transfer in solutions	44
Mechanical interlocking of SWNTs with N-rich macrocycles for efficient ORR electrocatalysis	44
In situ lattice tuning of quasi-single-crystal surfaces for continuous electrochemical modulation	44
Convergent chemoenzymatic synthesis of O-GalNAc rare cores 5, 7, 8 and their sialylated forms	44
Investigation of ion-electrode interactions of linear polyimides and alkali metal ions for next generation alternative-ion batteries	44
Wireless electrochemical light emission in ultrathin 2D nanoconfinements	44
Improving the interfacial stability of ultrahigh-nickel cathodes with PEO-based electrolytes by targeted chemical reactions	44
Plastic recognition and electrogenic uniport translocation of 1st-, 2nd-, and 3rd-row transition and post-transition metals by primary-active transmembrane P1B-2<	44
A domino-like localized cascade toehold assembly amplification-based DNA nanowire for microRNA imaging in living cells	43
Optical resolution via chiral auxiliaries of curved subphthalocyanine aromatics	43
Visualization of drug release in a chemo-immunotherapy nanoplatform via ratiometric 19F magnetic resonance imaging	43
One-pot chemical pyro- and tri-phosphorylation of peptides by using diamidophosphate in water	43
A directing group switch in copper-catalyzed electrophilic C–H amination/migratory annulation cascade: divergent access to benzimidazolone/benzimidazole	43
Design of discotic liquid crystal enabling complete switching along with memory of homeotropic and homogeneous alignment over a large area	43
Cascade-responsive size/charge bidirectional-tunable nanodelivery penetrates pancreatic tumor barriers	43
Supramolecular engineering cascade regulates NIR-II J-aggregates to improve photodynamic therapy	43
Hydrogen atom abstraction as a synthetic route to a square planar CoII complex with a redox-active tetradentate PNNP ligand	42
Enantioselective catalytic remote perfluoroalkylation of α-branched enals driven by light	42
Deducing the conformational space for an octa-proline helix	42
High-throughput screen with the l,d-transpeptidase LdtMt2 of Mycobacterium tuberculosis reveals novel classes of covalently reacting inhibitors	42
Universal dynamical onset in water at distinct material interfaces	42
Photoinduced metal-free borylation of aryl halides catalysed by an in situ formed donor–acceptor complex	42
Metastable doubly threaded [3]rotaxanes with a large macrocycle	42
The phenomenon of “dead” metal in heterogeneous catalysis: opportunities for increasing the efficiency of carbon-supported metal catalysts	42
DNA lesion-gated dumbbell nanodevices enable on-demand activation of the cGAS-STING pathway for enhancing cancer immunotherapy	42
Long-range hydrogen-bond relay catalyses the excited-state proton transfer reaction	42
Viscoelasticity of globular protein-based biomolecular condensates	42
The clinical potential of l-oligonucleotides: challenges and opportunities	42
Self-assembled PROTACs enable glycoproteins degradation in the living cells	42
Synthesis and reactivity of a six-membered heterocyclic 1,3-diphosphaallene	42
Experiment-guided molecular simulations define a heterogeneous structural ensemble for the PTPN11 tandem SH2 domains	42
Isomerization-induced fluorescence enhancement of two new viologen derivatives: mechanism insight and DFT calculations	42
Collective adaptability in a replication network of minimal nucleobase sequences	41
Cobalt- or rhodium-catalyzed synthesis of 1,2-dihydrophosphete oxides via C–H activation and formal phosphoryl migration	41
Engineered π⋯π interactions favour supramolecular dimers X@[FeL3]2 (X = Cl, Br, I): solid state and solution structure	41
Decoding the role of mycobacterial lipid remodelling and membrane dynamics in antibiotic tolerance	41
Dichlorine–pyridine N-oxide halogen-bonded complexes	41