OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Tissue Engineering is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Additively manufactured bioceramic scaffolds based on triply periodic minimal surfaces for bone regeneration	109
Advanced 3D bioprinted liver models with human-induced hepatocytes for personalized toxicity screening	107
Asymmetric biphasic electric stimulation supports cardiac maturation and functionality	97
An organotypic oral mucosal infection model to study host-pathogen interactions	79
Therapeutic potential and mechanisms of umbilical cord mesenchymal stem cells differentiating into tendon cells and promotion of rotator cuff tendon-bone healing	75
Decellularization for the retention of tissue niches	69
Promoting angiogenesis and diabetic wound healing through delivery of protein transduction domain-BMP2 formulated nanoparticles with hydrogel	64
Soft substrates direct stem cell differentiation into the chondrogenic lineage without the use of growth factors	57
Generation of a tendon-like tissue from human iPS cells	55
Corrigendum to “Tendon tissue engineering: An overview of biologics to promote tendon healing and repair”	50
Tissue-engineered composite tracheal grafts create mechanically stable and biocompatible airway replacements	46
Continuous nutrient supply culture strategy controls multivesicular endosomes pathway and anti-photo-aging miRNA cargo loading of extracellular vesicles	38
Advances in tissue engineering of peripheral nerve and tissue innervation – a systematic review	38
Construction of a pancreatic cancer nerve invasion system using brain and pancreatic cancer organoids	37
Differential stress responses of immunoisolated human islets embedded in pancreatic extracellular matrix under static and free-fall dynamic conditions	35
Steering the multipotent mesenchymal cells towards an anti-inflammatory and osteogenic bias via photobiomodulation therapy: How to kill two birds with one stone	34
Regeneration of articular cartilage defects: Therapeutic strategies and perspectives	33
Microfluidic organ-on-a-chip for modeling coronary artery disease: Recent applications, limitations and potential	33
Blood mononuclear cells induce accelerated vascular remodeling under acute inflammation in vitro	33
In vitro elastic cartilage reconstruction using human auricular perichondrial chondroprogenitor cell–derived micro 3D spheroids	32
Enhanced effects of antagomiR-3074-3p-conjugated PEI-AuNPs on the odontogenic differentiation by targeting FKBP9	32
Vascularized characteristics and functional regeneration of three-dimensional cell reconstruction of oral mucosa equivalents based on vascular homeostasis phenotypic modification	32
Gene editing strategies to address current challenges in stem cell-derived β cell therapy for type 1 Diabetes	30
Hair regeneration: Mechano-activation and related therapeutic approaches	30
Microvessels derived from hiPSCs are a novel source for angiogenesis and tissue regeneration	29

Advanced lung organoids for respiratory system and pulmonary disease modeling	29
Gum-on-a-Chip Exploring Host-Microbe Interactions: Periodontal Disease Modeling and Drug Discovery	28
Spheroid assembly of mesenchymal stem cells enhances secretome-mediated corneal reinnervation and epithelial repair in a mouse model of experimental dry eye	28
Design of an artificial natural killer cell mimicking system to target tumour cells	27
Stage-specific cardiotoxicity induced by bisphenol A using human pluripotent stem cell-derived 2D- and 3D-cardiomyocyte models	26
Emerging strategies for tissue engineering in vascularized composite allotransplantation: A review	26
Oxygenation and function of endocrine bioartificial pancreatic tissue constructs under flow for preclinical optimization	26
Exosomal non-coding RNAs: Emerging insights into therapeutic potential and mechanisms in bone healing	25
High-throughput, real-time monitoring of engineered skeletal muscle function using magnetic sensing	24
Nanodrug delivery systems for regulating microglial polarization in ischemic stroke treatment: A review	24
Preclinical and clinical orthotopic transplantation of decellularized/engineered tracheal scaffolds: A systematic literature review	24
Cell secretomes for wound healing and tissue regeneration: Next generation acellular based tissue engineered products	24
Development of an iPSC-derived immunocompetent skin model for identification of skin sensitizing substances	24
In situ regeneration of nasal septal defects using acellular cartilage enhanced with platelet-derived growth factor	23
Immunomodulation in diabetic wounds healing: The intersection of macrophage reprogramming and immunotherapeutic hydrogels	23
A global bibliometric and visualized analysis in the status and trends of corneal tissue engineering research from 1991 to 2021	23
Engineering growth factor gradients to drive spatiotemporal tissue patterning in organ-on-a-chip systems	22
Expanding tubular microvessels on stiff substrates with endothelial cells and pericytes from the same adult tissue	22
Non-hypertrophic chondrogenesis of mesenchymal stem cells through mechano-hypoxia programing	21
Liver scaffolds obtained by decellularization: A transplant perspective in liver bioengineering	21
Intranasal delivery systems for traumatic brain injury: Advancements and perspectives	21
Tendon tissue engineering: An overview of biologics to promote tendon healing and repair	21
A new cell-free therapeutic strategy for liver regeneration: Human placental mesenchymal stem cell-derived extracellular vesicles	21
Advances in hydrogels for capturing and neutralizing inflammatory cytokines	20
Controlled spatial and temporal release of neurotrophic growth factor from genetically modified tissue engineering living scaffolds	20
RANKL neutralisation prevents osteoclast activation in a human in vitro ameloblastoma-bone model	20
SP7 gene silencing dampens bone marrow stromal cell hypertrophy, but it also dampens chondrogenesis	19
Two-dimensional vascularized liver organoid on extracellular matrix with defined stiffness for modeling fibrotic and normal tissues	18
Retraction: Estradiol-17β [E2] stimulates wound healing in a 3D in vitro tissue-engineered vaginal wound model	18
Comprehensive evaluation of cryopreserved aortic homografts: Long-term mechanical and histological preservation across human and porcine models	17
Extracellular vesicles delivering nuclear factor I/C for hard tissue engineering: Treatment of apical periodontitis and dentin regeneration	17
Peptide nanogels as a scaffold for fabricating dermal grafts and 3D vascularized skin models	17
Mechanically activated mesenchymal-derived bone cells drive vessel formation via an extracellular vesicle mediated mechanism	16
Repairing a critical cranial defect using WISP1-pretreated chondrocyte scaffolds	16
Formation of neutrophil extracellular traps in the early stages exacerbate the healing process by regulating macrophage polarization in Achilles tendon-bone injury	16
Comparison of bone formation mediated by bone morphogenetic protein delivered by nanoclay gels with clinical techniques (autograft and InductOs^®) in an ovine bone model	16
Bioengineering strategies targeting angiogenesis: Innovative solutions for osteonecrosis of the femoral head	16
Unlocking the regenerative key: Targeting stem cell factors for bone renewal	16
Hamster organotypic kidney culture model of early-stage SARS-CoV-2 infection highlights a two-step renal susceptibility	16
Position Paper Progress in the development of biomimetic engineered human tissues	15
Transplantation of engineered endothelial progenitor cells with H19 overexpression promotes arterial reendothelialization and inhibits neointimal hyperplasia	15
GDF15 promotes osteogenic differentiation of human dental pulp stem cells by activating the TGF-β/SMAD signaling pathway	15
New insights into balancing wound healing and scarless skin repair	15
Mechanisms of hydrogel-based microRNA delivery systems and its application strategies in targeting inflammatory diseases	15
Bioactivated scaffolds promote angiogenesis and lymphangiogenesis for dermal regeneration in vivo	15
Decellularized extracellular matrix for organoid and engineered organ culture	14
SPI1 facilitates microfracture-mediated cartilage regeneration in the elderly by enhancing bone marrow stromal cells stemness	14
Developing human upper, lower, and deep lung airway models: Combining different scaffolds and developing complex co-cultures	14
Enhanced interaction between genome-edited mesenchymal stem cells and platelets improves wound healing in mice	13
Rat liver extracellular matrix and perfusion bioreactor culture promote human amnion epithelial cell differentiation towards hepatocyte-like cells	13

3-D tissue-engineered epidermis against human primary keratinocytes apoptosis via relieving mitochondrial oxidative stress in wound healing	13
Construction of artificial lung tissue structure with 3D-inkjet bioprinting core for pulmonary disease evaluation	12
Disc regeneration by injectable fucoidan-methacrylated dextran hydrogels through mechanical transduction and macrophage immunomodulation	12
Development of a reliable method for human triple-negative breast cancer organotypic culture: Improving imaging and genomic studies in 3D cultures	12
Synthetic injectable and porous hydrogels for the formation of skeletal muscle fibers: Novel perspectives for the acellular repair of substantial volumetric muscle loss	12
Osteoarthritis models: From animals to tissue engineering	12
Epigenetics: Novel crucial approach for osteogenesis of mesenchymal stem cells	12
Revolutionizing digestive system tumor organoids research: Exploring the potential of tumor organoids	12
Recent advance in treatment of atherosclerosis: Key targets and plaque-positioned delivery strategies	12
Differential immune responses of 3D gingival and periodontal connective tissue equivalents to microbial colonization	12
Novel 3D printed TPMS scaffolds: microstructure, characteristics and applications in bone regeneration	11
Engineering transplantable human lymphatic and blood capillary networks in a porous scaffold	11
Human three-dimensional engineered muscle tissue characterization and intramyocellular lipid modeling	11
Cell shape characteristics of human skeletal muscle cells as a predictor of myogenic competency: A new paradigm towards precision cell therapy	11
Development of human salivary gland cell lines for modeling radiation-induced damage in three-dimensional spheroid cultures	11
Bio-electrospraying assessment toward in situ chondrocyte-laden electrospun scaffold fabrication	11
Cell-free osteoarthritis treatment with dual-engineered chondrocyte-targeted extracellular vesicles derived from mechanical loading primed mesenchymal stem cells	11
From in vivo models to in vitro bioengineered neuromuscular junctions for the study of Charcot-Marie-Tooth disease	11
Enhancement structural and signaling microenvironment of artificial tumor extracellular matrix for enhanced drug screening	11
Precision-engineered niche for directed differentiation of MSCs to lineage-restricted mineralized tissues	10
Transplantation of engineered vascularized lymphatic tissue using LEC and in vivo AV loop model to enhance lymphangiogenesis and restore lymphatic drainage in a lymphadenectomy rat model	10
Targeting connexin 43 expression via scaffold mediated delivery of antisense oligodeoxynucleotide preserves neurons, enhances axonal extension, reduces astrocyte and microglial activation after spinal	10
Decellularization of tumours: A new frontier in tissue engineering	10
Collagenase treatment appears to improve cartilage tissue integration but damage to collagen networks is likely permanent	9
Construction of functional tissue-engineered microvasculatures using circulating fibrocytes as mural cells	9
Mesenchymal stem cells overexpressing XIST induce macrophage M2 polarization and improve neural stem cell homeostatic microenvironment, alleviating spinal cord injury	9
Restoration of olfactory dysfunctions by nanomaterials and stem cells-based therapies: Current status and future perspectives	9
Fibrous hydrogels by electrospinning: Novel platforms for biomedical applications	9
Method for manufacture and cryopreservation of cartilage microtissues	9
Amelioration of intervertebral disc degeneration using engineered extracellular vesicle-delivered ZDHHC5 via inhibiting PANoptosis	9
Single-cell RNA-sequence analysis of human bone marrow reveals new targets for isolation of skeletal stem cells using spherical nucleic acids	8
Efficient generation of human cerebral organoids directly from adherent cultures of pluripotent stem cells	8
Full-length dystrophin deficiency leads to contractile and calcium transient defects in human engineered heart tissues	8
Modeling the blood-brain barrier for treatment of central nervous system (CNS) diseases	8
Strain-induced bands of Büngner formation promotes axon growth in 3D tissue-engineered constructs	8
In vivo vascularized scaffold with different shear-exposed models for lymphatic tissue regeneration	8
Adipose tissue derived stem cell secretome induces motor and histological gains after complete spinal cord injury in Xenopus laevis and mice	8
In vitro maturation and in vivo stability of bioprinted human nasal cartilage	8