OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Tissue Engineering is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Synthetic injectable and porous hydrogels for the formation of skeletal muscle fibers: Novel perspectives for the acellular repair of substantial volumetric muscle loss	75
Advanced 3D bioprinted liver models with human-induced hepatocytes for personalized toxicity screening	58
In situ regeneration of nasal septal defects using acellular cartilage enhanced with platelet-derived growth factor	52
Harnessing bone marrow mesenchymal stem cell-derived extracellular vesicles and biomimetic peptide WKYMVm in self-healing hydrogel for enhanced bone repair in femoral defects	50
Osteogenesis in the presence of chemotherapy: A biomimetic approach	48
Therapeutic arteriogenesis by factor-decorated fibrin matrices promotes wound healing in diabetic mice	42
Therapeutic potential and mechanisms of umbilical cord mesenchymal stem cells differentiating into tendon cells and promotion of rotator cuff tendon-bone healing	41
Self-assembling peptide gels promote angiogenesis and functional recovery after spinal cord injury in rats	38
Tendon tissue engineering: An overview of biologics to promote tendon healing and repair	30
Additively manufactured bioceramic scaffolds based on triply periodic minimal surfaces for bone regeneration	29
Strategy for improving cell-mediated vascularized soft tissue formation in a hydrogen peroxide-triggered chemically-crosslinked hydrogel	26
3D bioprinting of the airways and lungs for applications in tissue engineering and in vitro models	26
An organotypic oral mucosal infection model to study host-pathogen interactions	26
Recent advance in treatment of atherosclerosis: Key targets and plaque-positioned delivery strategies	25
Extracellular matrix-derived peptide stimulates the generation of endocrine progenitors and islet organoids from iPSCs	24
A global bibliometric and visualized analysis in the status and trends of corneal tissue engineering research from 1991 to 2021	24
Promoting angiogenesis and diabetic wound healing through delivery of protein transduction domain-BMP2 formulated nanoparticles with hydrogel	23
Epigenetics: Novel crucial approach for osteogenesis of mesenchymal stem cells	22
Disc regeneration by injectable fucoidan-methacrylated dextran hydrogels through mechanical transduction and macrophage immunomodulation	21
Innovative bioinks for 3D bioprinting: Exploring technological potential and regulatory challenges	20
Decellularization for the retention of tissue niches	19
Application of microneedle patches for drug delivery; doorstep to novel therapies	19
Expanding tubular microvessels on stiff substrates with endothelial cells and pericytes from the same adult tissue	19
Cell-free osteoarthritis treatment with dual-engineered chondrocyte-targeted extracellular vesicles derived from mechanical loading primed mesenchymal stem cells	18
In vitro and ex vivo models of the oral mucosa as platforms for the validation of novel drug delivery systems	17

Bio-electrospraying assessment toward in situ chondrocyte-laden electrospun scaffold fabrication	17
Advances in tissue engineering of peripheral nerve and tissue innervation – a systematic review	17
Human mini brains and spinal cords in a dish: Modeling strategies, current challenges, and prospective advances	17
Controlled vitamin D delivery with injectable hyaluronic acid-based hydrogel for restoration of tendinopathy	17
Establishment of the SIS scaffold-based 3D model of human peritoneum for studying the dissemination of ovarian cancer	16
Continuous nutrient supply culture strategy controls multivesicular endosomes pathway and anti-photo-aging miRNA cargo loading of extracellular vesicles	16
Differential immune responses of 3D gingival and periodontal connective tissue equivalents to microbial colonization	15
Generation of a tendon-like tissue from human iPS cells	15
Liver scaffolds obtained by decellularization: A transplant perspective in liver bioengineering	15
Enhancing pre-clinical research with simplified intestinal cell line models	15
Enhancement structural and signaling microenvironment of artificial tumor extracellular matrix for enhanced drug screening	14
Tissue engineering in growth plate cartilage regeneration: Mechanisms to therapeutic strategies	14
Adipose tissue-derived microvascular fragments promote lymphangiogenesis in a murine lymphedema model	14
Engineering transplantable human lymphatic and blood capillary networks in a porous scaffold	13
3D Bioprinting tissue analogs: Current development and translational implications	13
A new cell-free therapeutic strategy for liver regeneration: Human placental mesenchymal stem cell-derived extracellular vesicles	13
Current progress and challenges in the development of brain tissue models: How to grow up the changeable brain in vitro?	13
Advancing skin model development: A focus on a self-assembled, induced pluripotent stem cell-derived, xeno-free approach	12
Therapeutic potential of epiphyseal growth plate cells for bone regeneration in an osteoporosis model	12
From in vivo models to in vitro bioengineered neuromuscular junctions for the study of Charcot-Marie-Tooth disease	12
Molecular and electrophysiological evaluation of human cardiomyocyte subtypes to facilitate generation of composite cardiac models	12
Construction of a pancreatic cancer nerve invasion system using brain and pancreatic cancer organoids	12
Significance of mechanical loading in bone fracture healing, bone regeneration, and vascularization	11
Therapeutic potential of luteolin-loaded poly(lactic-co-glycolic acid)/modified magnesium hydroxide microsphere in functional thermosensitive hydrogel for treating neuropathic pain	11
Novel 3D printed TPMS scaffolds: microstructure, characteristics and applications in bone regeneration	11
Technological advances in fibrin for tissue engineering	11
Soft substrates direct stem cell differentiation into the chondrogenic lineage without the use of growth factors	11
Precision-engineered niche for directed differentiation of MSCs to lineage-restricted mineralized tissues	10
Cell shape characteristics of human skeletal muscle cells as a predictor of myogenic competency: A new paradigm towards precision cell therapy	10
Steering the multipotent mesenchymal cells towards an anti-inflammatory and osteogenic bias via photobiomodulation therapy: How to kill two birds with one stone	10
Tissue-engineered composite tracheal grafts create mechanically stable and biocompatible airway replacements	10
Fibrous hydrogels by electrospinning: Novel platforms for biomedical applications	10
3D bioprinting of corneal models: A review of the current state and future outlook	9
Targeting connexin 43 expression via scaffold mediated delivery of antisense oligodeoxynucleotide preserves neurons, enhances axonal extension, reduces astrocyte and microglial activation after spinal	9
Discovery of bioactive peptides as therapeutic agents for skin wound repair	9
Non-hypertrophic chondrogenesis of mesenchymal stem cells through mechano-hypoxia programing	9
Decellularization of tumours: A new frontier in tissue engineering	9
Engineered extracellular vesicle-delivered TGF-β inhibitor for attenuating osteoarthritis by targeting subchondral bone	8
Vascularized characteristics and functional regeneration of three-dimensional cell reconstruction of oral mucosa equivalents based on vascular homeostasis phenotypic modification	7
Meniscus regeneration by 3D printing technologies: Current advances and future perspectives	7
The rise of mechanical metamaterials: Auxetic constructs for skin wound healing	7
A survey to evaluate parameters governing the selection and application of extracellular vesicle isolation methods	7
Multimodal analysis of the differential effects of cyclic strain on collagen isoform composition, fibril architecture and biomechanics of tissue engineered tendon	7
RANKL neutralisation prevents osteoclast activation in a human in vitro ameloblastoma-bone model	7
Mesenchymal stem cells establish a pro-regenerative immune milieu after decellularized rat uterus tissue transplantation	7
Regeneration of articular cartilage defects: Therapeutic strategies and perspectives	7
Microenvironmental dynamics of diabetic wounds and insights for hydrogel-based therapeutics	7
Bioinspired synthetic peptide-based biomaterials regenerate bone through biomimicking of extracellular matrix	7
Induced pluripotent stem cell-based organ-on-a-chip as personalized drug screening tools: A focus on neurodegenerative disorders	7
Full-length dystrophin deficiency leads to contractile and calcium transient defects in human engineered heart tissues	6

Restoration of olfactory dysfunctions by nanomaterials and stem cells-based therapies: Current status and future perspectives	6
Construction of functional tissue-engineered microvasculatures using circulating fibrocytes as mural cells	6
Targeting ROS in osteoclasts within the OA environment: A novel therapeutic strategy for osteoarthritis management	6
In vitro elastic cartilage reconstruction using human auricular perichondrial chondroprogenitor cell–derived micro 3D spheroids	6
Modeling of solar UV-induced photodamage on the hair follicles in human skin organoids	6
Bioengineering strategies targeting angiogenesis: Innovative solutions for osteonecrosis of the femoral head	6
Rapid and efficient generation of cartilage pellets from mouse induced pluripotent stem cells by transcriptional activation of BMP-4 with shaking culture	6
Method for manufacture and cryopreservation of cartilage microtissues	6
Bioengineered cartilaginous grafts for repairing segmental mandibular defects	5
Advanced strategies for constructing interfacial tissues of bone and tendon/ligament	5
Establishing an hTERT-driven immortalized umbilical cord-derived mesenchymal stem cell line and its therapeutic application in mice with liver failure	5
Mesenchymal stem cells overexpressing XIST induce macrophage M2 polarization and improve neural stem cell homeostatic microenvironment, alleviating spinal cord injury	5
SP7 gene silencing dampens bone marrow stromal cell hypertrophy, but it also dampens chondrogenesis	5
Insulin resistance compromises midbrain organoid neuronal activity and metabolic efficiency predisposing to Parkinson’s disease pathology	5
In vitro maturation and in vivo stability of bioprinted human nasal cartilage	5