OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Tissue Engineering is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
An organotypic oral mucosal infection model to study host-pathogen interactions	137
Therapeutic potential and mechanisms of umbilical cord mesenchymal stem cells differentiating into tendon cells and promotion of rotator cuff tendon-bone healing	113
Promoting angiogenesis and diabetic wound healing through delivery of protein transduction domain-BMP2 formulated nanoparticles with hydrogel	108
Additively manufactured bioceramic scaffolds based on triply periodic minimal surfaces for bone regeneration	89
Advanced 3D bioprinted liver models with human-induced hepatocytes for personalized toxicity screening	71
Asymmetric biphasic electric stimulation supports cardiac maturation and functionality	64
Advances in tissue engineering of peripheral nerve and tissue innervation – a systematic review	60
Construction of a pancreatic cancer nerve invasion system using brain and pancreatic cancer organoids	54
Corrigendum to “Tendon tissue engineering: An overview of biologics to promote tendon healing and repair”	47
Continuous nutrient supply culture strategy controls multivesicular endosomes pathway and anti-photo-aging miRNA cargo loading of extracellular vesicles	44
Differential stress responses of immunoisolated human islets embedded in pancreatic extracellular matrix under static and free-fall dynamic conditions	42
Vascularized characteristics and functional regeneration of three-dimensional cell reconstruction of oral mucosa equivalents based on vascular homeostasis phenotypic modification	41
Advances in esophageal organoids: from construction to applications	37
Blood mononuclear cells induce accelerated vascular remodeling under acute inflammation in vitro	37
Microfluidic organ-on-a-chip for modeling coronary artery disease: Recent applications, limitations and potential	36
Enhanced effects of antagomiR-3074-3p-conjugated PEI-AuNPs on the odontogenic differentiation by targeting FKBP9	35
Regeneration of articular cartilage defects: Therapeutic strategies and perspectives	35
Gene editing strategies to address current challenges in stem cell-derived β cell therapy for type 1 Diabetes	33
Gum-on-a-Chip Exploring Host-Microbe Interactions: Periodontal Disease Modeling and Drug Discovery	31
Hair regeneration: Mechano-activation and related therapeutic approaches	31
Advanced lung organoids for respiratory system and pulmonary disease modeling	31
Preclinical and clinical orthotopic transplantation of decellularized/engineered tracheal scaffolds: A systematic literature review	28
Emerging strategies for tissue engineering in vascularized composite allotransplantation: A review	27
Design of an artificial natural killer cell mimicking system to target tumour cells	27
Exosomal non-coding RNAs: Emerging insights into therapeutic potential and mechanisms in bone healing	27

Nanodrug delivery systems for regulating microglial polarization in ischemic stroke treatment: A review	26
Spheroid assembly of mesenchymal stem cells enhances secretome-mediated corneal reinnervation and epithelial repair in a mouse model of experimental dry eye	25
Oxygenation and function of endocrine bioartificial pancreatic tissue constructs under flow for preclinical optimization	25
Immunomodulation in diabetic wounds healing: The intersection of macrophage reprogramming and immunotherapeutic hydrogels	23
Stage-specific cardiotoxicity induced by bisphenol A using human pluripotent stem cell-derived 2D- and 3D-cardiomyocyte models	22
Development of an iPSC-derived immunocompetent skin model for identification of skin sensitizing substances	21
Noncoding RNAs in chronic wound healing: Mechanisms, exosome therapeutics, and translational frontiers	20
Engineering growth factor gradients to drive spatiotemporal tissue patterning in organ-on-a-chip systems	19
Adipose mesenchymal stem cell-derived nanovesicles as a therapeutic strategy for oral mucosal regeneration after chemotherapy in a rat model	19
Tendon tissue engineering: An overview of biologics to promote tendon healing and repair	19
Non-hypertrophic chondrogenesis of mesenchymal stem cells through mechano-hypoxia programing	19
Evaluating the electrical stimulation of bone cells based on an induced transmembrane potential model and intracellular calcium levels	18
Controlled spatial and temporal release of neurotrophic growth factor from genetically modified tissue engineering living scaffolds	18
Retraction: Estradiol-17β [E2] stimulates wound healing in a 3D in vitro tissue-engineered vaginal wound model	17
Intranasal delivery systems for traumatic brain injury: Advancements and perspectives	17
Unlocking the regenerative key: Targeting stem cell factors for bone renewal	17
Advances in hydrogels for capturing and neutralizing inflammatory cytokines	17
Comprehensive evaluation of cryopreserved aortic homografts: Long-term mechanical and histological preservation across human and porcine models	17
Bioengineering strategies targeting angiogenesis: Innovative solutions for osteonecrosis of the femoral head	16
Mechanically activated mesenchymal-derived bone cells drive vessel formation via an extracellular vesicle mediated mechanism	16
SP7 gene silencing dampens bone marrow stromal cell hypertrophy, but it also dampens chondrogenesis	16
Two-dimensional vascularized liver organoid on extracellular matrix with defined stiffness for modeling fibrotic and normal tissues	15
Transplantation of engineered endothelial progenitor cells with H19 overexpression promotes arterial reendothelialization and inhibits neointimal hyperplasia	15
Mechanisms of hydrogel-based microRNA delivery systems and its application strategies in targeting inflammatory diseases	14
Position Paper Progress in the development of biomimetic engineered human tissues	14
SPI1 facilitates microfracture-mediated cartilage regeneration in the elderly by enhancing bone marrow stromal cells stemness	14
Developing human upper, lower, and deep lung airway models: Combining different scaffolds and developing complex co-cultures	13
Bioactivated scaffolds promote angiogenesis and lymphangiogenesis for dermal regeneration in vivo	13
GDF15 promotes osteogenic differentiation of human dental pulp stem cells by activating the TGF-β/SMAD signaling pathway	12
Fibro-adipogenic progenitors enhance functional and structural properties of human 3D tissue engineered skeletal muscles	12
New insights into balancing wound healing and scarless skin repair	12
Formation of neutrophil extracellular traps in the early stages exacerbate the healing process by regulating macrophage polarization in Achilles tendon-bone injury	12
Repairing a critical cranial defect using WISP1-pretreated chondrocyte scaffolds	11
Decellularized extracellular matrix for organoid and engineered organ culture	11
Rat liver extracellular matrix and perfusion bioreactor culture promote human amnion epithelial cell differentiation towards hepatocyte-like cells	11
Enhanced interaction between genome-edited mesenchymal stem cells and platelets improves wound healing in mice	10
3-D tissue-engineered epidermis against human primary keratinocytes apoptosis via relieving mitochondrial oxidative stress in wound healing	10
Revolutionizing digestive system tumor organoids research: Exploring the potential of tumor organoids	10
Osteoarthritis models: From animals to tissue engineering	9
Synthetic injectable and porous hydrogels for the formation of skeletal muscle fibers: Novel perspectives for the acellular repair of substantial volumetric muscle loss	9
Construction of artificial lung tissue structure with 3D-inkjet bioprinting core for pulmonary disease evaluation	9
Epigenetics: Novel crucial approach for osteogenesis of mesenchymal stem cells	9
Biomaterials-based engineering of the bone microenvironment for osteoporosis therapy	9
Development of a reliable method for human triple-negative breast cancer organotypic culture: Improving imaging and genomic studies in 3D cultures	9
Disc regeneration by injectable fucoidan-methacrylated dextran hydrogels through mechanical transduction and macrophage immunomodulation	8
Early vascularization as a key feature of muscle-in-vein grafts for peripheral nerve repair	8
Cell shape characteristics of human skeletal muscle cells as a predictor of myogenic competency: A new paradigm towards precision cell therapy	7
Human three-dimensional engineered muscle tissue characterization and intramyocellular lipid modeling	7
Novel 3D printed TPMS scaffolds: microstructure, characteristics and applications in bone regeneration	7
From in vivo models to in vitro bioengineered neuromuscular junctions for the study of Charcot-Marie-Tooth disease	7

Enhancement structural and signaling microenvironment of artificial tumor extracellular matrix for enhanced drug screening	7
Cell-free osteoarthritis treatment with dual-engineered chondrocyte-targeted extracellular vesicles derived from mechanical loading primed mesenchymal stem cells	7
Development of human salivary gland cell lines for modeling radiation-induced damage in three-dimensional spheroid cultures	7
Targeting connexin 43 expression via scaffold mediated delivery of antisense oligodeoxynucleotide preserves neurons, enhances axonal extension, reduces astrocyte and microglial activation after spinal	6
Construction of functional tissue-engineered microvasculatures using circulating fibrocytes as mural cells	6
Amelioration of intervertebral disc degeneration using engineered extracellular vesicle-delivered ZDHHC5 via inhibiting PANoptosis	6
Fibrous hydrogels by electrospinning: Novel platforms for biomedical applications	6
Mesenchymal stem cells overexpressing XIST induce macrophage M2 polarization and improve neural stem cell homeostatic microenvironment, alleviating spinal cord injury	6
Transplantation of engineered vascularized lymphatic tissue using LEC and in vivo AV loop model to enhance lymphangiogenesis and restore lymphatic drainage in a lymphadenectomy rat model	6
Strain-induced bands of Büngner formation promotes axon growth in 3D tissue-engineered constructs	6