Cell and Bioscience

Article	Citations
Correction: Plasma metabolomics provides new insights into the relationship between metabolites and outcomes and left ventricular remodeling of coronary artery disease	189
Generation of musculoskeletal cells from human urine epithelium-derived presomitic mesoderm cells	168
Integrating spatial transcriptomics with single-cell transcriptomics reveals a spatiotemporal gene landscape of the human developing kidney	157
Retraction Note: Growth inhibition and apoptosis in colorectal cancer cells induced by vitamin D-Nanoemulsion (NVD): involvement of Wnt/β-catenin and other signal transduction pathways	130
Genome-wide association study of the fatty liver index in the Taiwanese population reveals shared and population-specific genetic risk factors across ethnicities	125
HBx promotes tumorigenicity through RRM2-mediated autophagy in hepatocellular carcinoma	119
Comparative proteomic profiling of plasma exosomes in lung cancer cases of liver and brain metastasis	117
Microvascular destabilization and intricated network of the cytokines in diabetic retinopathy: from the perspective of cellular and molecular components	102
Electric field stimulation boosts neuronal differentiation of neural stem cells for spinal cord injury treatment via PI3K/Akt/GSK-3β/β-catenin activation	98
Slit-Robo expression in the leech nervous system: insights into eyespot evolution	86
Bromodomain proteins as potential therapeutic targets for B-cell non-Hodgkin lymphoma	83
Autophagy-mediated degradation of NOTCH1 intracellular domain controls the epithelial to mesenchymal transition and cancer metastasis	81
Retraction Note: LncRNA SNHG7 promotes pancreatic cancer proliferation through ID4 by sponging miR-342-3p	76
Multi-omics in thoracic aortic aneurysm: the complex road to the simplification	72
Integrative analysis of bulk and single-cell RNA sequencing reveals the gene expression profile and the critical signaling pathways of type II CPAM	71
Correction: The dual role of mTOR signaling in lung development and adult lung diseases	60
Sperm-borne small non-coding RNAs: potential functions and mechanisms as epigenetic carriers	59
A new thinking: deciphering the aberrance and clinical implication of copper-death signatures in clear cell renal cell carcinoma	57
Metabolic reprogramming in colorectal cancer: regulatory networks and therapy	56
Transcriptome-scale spatial gene expression in rat arcuate nucleus during puberty	55
Neurokinin-2 receptor negatively modulates substance P responses by forming complex with Neurokinin-1 receptor	51
Single-cell genomics identifies distinct B1 cell developmental pathways and reveals aging-related changes in the B-cell receptor repertoire	50
Long-term maintenance of human endometrial epithelial stem cells and their therapeutic effects on intrauterine adhesion	49
PI3K-AKT activation resculpts integrin signaling to drive filamentous tau-induced proinflammatory astrogliosis	48
Clinical biomarkers for Lewy body diseases	48

Brain nuclear receptors and cardiovascular function	48
Tick-borne encephalitis affects sleep–wake behavior and locomotion in infant rats	46
Modulation of foraging-like behaviors by cholesterol-FGF19 axis	46
PGCLCs of human 45,XO reveal pathogenetic pathways of neurocognitive and psychosocial disorders	45
Neural EGFL-like 1, a craniosynostosis-related osteochondrogenic molecule, strikingly associates with neurodevelopmental pathologies	45
Hypofucosylation of Unc5b regulated by Fut8 enhances macrophage emigration and prevents atherosclerosis	44
New insights into the stromal interaction molecule 2 function and its impact on the immunomodulation of tumor microenvironment	44
A patient-derived mutation of epilepsy-linked LGI1 increases seizure susceptibility through regulating Kv1.1	43
Single-cell analysis of mouse uterus at the invasion phase of embryo implantation	43
SIRT6 deficiency impairs the deacetylation and ubiquitination of UHRF1 to strengthen glycolysis and lactate secretion in bladder cancer	41
RNA sequencing profiles reveal dynamic signaling and glucose metabolic features during bone marrow mesenchymal stem cell senescence	41
Sex-specific hypothalamic neuropathology and glucose metabolism in an amyloidosis transgenic mouse model of Alzheimer’s disease	41
The dual role of mTOR signaling in lung development and adult lung diseases	38
The cGAS-STING pathway in cardiovascular diseases: from basic research to clinical perspectives	38
Precision nephrotoxicity testing using 3D in vitro models	38
SARS-CoV-2 variants divergently infect and damage cardiomyocytes in vitro and in vivo	38
Targeting G-quadruplex for rescuing impaired chondrogenesis in WRN-deficient stem cells	37
Calcineurin inhibition protects against dopamine toxicity and attenuates behavioral decline in a Parkinson’s disease model	37
DNA methyltransferase 1 knockdown reverses PTEN and VDR by mediating demethylation of promoter and protects against renal injuries in hepatitis B virus-associated glomerulonephritis	37
The nerve growth factor-delivered signals in prostate cancer and its associated microenvironment: when the dialogue replaces the monologue	36
Clostridium butyricum regulates intestinal barrier function via trek1 to improve behavioral abnormalities in mice with autism spectrum disorder	36
Fibroblast-to-cardiomyocyte lactate shuttle modulates hypertensive cardiac remodelling	36
Autophagy deficiency in neurodevelopmental disorders	36
Dynamic single-cell RNA-seq analysis reveals distinct tumor program associated with microenvironmental remodeling and drug sensitivity in multiple myeloma	35
Modeling of the brain-lung axis using organoids in traumatic brain injury: an updated review	35
The multifaceted therapeutic value of targeting steroid receptor coactivator-1 in tumorigenesis	35
NAD+ metabolism-based immunoregulation and therapeutic potential	34
Regulation of telomerase towards tumor therapy	34
Editorial Expression of Concern: Ginkgetin aglycone ameliorates LPS-induced acute kidney injury by activating SIRT1 via inhibiting the NF-κB signaling pathway	34
ER Ca2+ overload activates the IRE1α signaling and promotes cell survival	34
Uncoupling p38α nuclear and cytoplasmic functions and identification of two p38α phosphorylation sites on β-catenin: implications for the Wnt signaling pathway in CRC models	34
CXCL11 reprograms M2-biased macrophage polarization to alleviate pulmonary fibrosis in mice	33
TRIM22 suppresses Zika virus replication by targeting NS1 and NS3 for proteasomal degradation	33
DNA in extracellular vesicles: from evolution to its current application in health and disease	33
Hippocampal CA1 neuron, a crucial regulator for chronic stress exacerbating Alzheimer’s disease progression	33
Insight into the mitochondrial unfolded protein response and cancer: opportunities and challenges	32
Programmed cell death in the cognitive impairment of obstructive sleep apnea	32
BVES is a novel interactor of ANO5 and regulates myoblast differentiation	31
CircRNA Itm2b induces oxidative stress via the interaction with Sirt1-Nox4 to aggravate sleep disturbances after traumatic brain injury	31
Current methodologies in protein ubiquitination characterization: from ubiquitinated protein to ubiquitin chain architecture	31
Alkylglycerol monooxygenase represses prostanoid biosynthesis in a sex-dependent manner	30
Exosomes originating from infection with the cytoplasmic single-stranded RNA virus Rift Valley fever virus (RVFV) protect recipient cells by inducing RIG-I mediated IFN-B response that leads to activa	30
The phosphorylation to acetylation/methylation cascade in transcriptional regulation: how kinases regulate transcriptional activities of DNA/histone-modifying enzymes	30
Inhibition of PI3 kinase isoform p110α suppresses neuroblastoma growth and induces the reduction of Anaplastic Lymphoma Kinase	30
Umbelliferone and eriodictyol suppress the cellular entry of SARS-CoV-2	30
Nrf2 is predominantly expressed in hippocampal neurons in a rat model of temporal lobe epilepsy	29
Coffee as a dietary strategy to prevent SARS-CoV-2 infection	29
ISG15 suppresses ovulation and female fertility by ISGylating ADAMTS1	29
A synthetic pregnenolone analog promotes microtubule dynamics and neural development	29
Structural basis of human PRPS2 filaments	29

Hypoxia increases RCC stem cell phenotype via altering the androgen receptor (AR)-lncTCFL5-2-YBX1-SOX2 signaling axis	29
Zinc finger protein Zfp335 is required for T cell homeostatic proliferation through regulating Lmnb1	29
Inhibition of sphingolipid metabolism in osteosarcoma protects against CD151-mediated tumorigenicity	28
Chemically defined and xeno-free media enables the derivation of human extended pluripotent stem cell lines from discarded blastocysts with a high efficiency	28
Transcriptomic characterization of tissues from patients and subsequent pathway analyses reveal biological pathways that are implicated in spastic ataxia	28
HnRNP M expression rescues neurodegeneration in neuronal intranuclear inclusion disease mouse model by restoring dysregulated RNA splicing and transcription	28
A cost-effective machine learning-based method for preeclampsia risk assessment and driver genes discovery	27
Macrophage-derived exosomes mediate glomerular endothelial cell dysfunction in sepsis-associated acute kidney injury	27
The eukaryotic initiation factor 5A (eIF5A1), the molecule, mechanisms and recent insights into the pathophysiological roles	27
Rab11a-dependent recycling of Glut3 inhibits seizure-induced neuronal disulfidptosis by alleviating glucose deficiency	27
Unraveling the serotonin saga: from discovery to weight regulation and beyond - a comprehensive scientific review	27
Discovery and mechanism studies of a novel ATG4B inhibitor Ebselen by drug repurposing and its anti-colorectal cancer effects in mice	27
Advancing equity through strengthening research on health and well-being of Asian American, Native Hawaiian, and Pacific Islander	27
ANGPTL2 binds MAG to efficiently enhance oligodendrocyte differentiation	27
The RBM39 degrader indisulam inhibits acute megakaryoblastic leukemia by altering the alternative splicing of ZMYND8	27
Cutting-edge advances in modeling the blood–brain barrier and tools for its reversible permeabilization for enhanced drug delivery into the brain	27
Integrated single-nucleus sequencing and spatial architecture analysis identified distinct injured-proximal tubular types in calculi rats	26
V1bR enhances glucose-stimulated insulin secretion by paracrine production of glucagon which activates GLP-1 receptor	26
SETD8, a frequently mutated gene in cervical cancer, enhances cisplatin sensitivity by impairing DNA repair	26
Therapeutic uses of oxytocin in stress-related neuropsychiatric disorders	25
The role of the striatin family proteins in hippo signaling and cellular regulation	25
The immunological mechanisms and therapeutic potential in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity	25
The regulatory mechanism of neutrophil extracellular traps in cancer biological behavior	25
Mutation-class dependent signatures outweigh disease-associated processes in cystic fibrosis cells	25
Astrocyte derived TSP2 contributes to synaptic alteration and visual dysfunction in retinal ischemia/reperfusion injury	25
Klotho exerts protection in chronic kidney disease associated with regulating inflammatory response and lipid metabolism	24
Bone morphogenetic protein signaling regulation of AMPK and PI3K in lung cancer cells and C. elegans	24
GSTM2 alleviates heart failure by inhibiting DNA damage in cardiomyocytes	24
TAZ deficiency exacerbates psoriatic pathogenesis by increasing the histamine-releasing factor	24
DNA methylation of ACADS promotes immunogenic cell death in hepatocellular carcinoma	24
Damage mechanism and therapy progress of the blood-brain barrier after ischemic stroke	24
Canonical and non-canonical functions of the non-coding RNA component (TERC) of telomerase complex	23
Knocking out Fkbp51 decreases CCl4-induced liver injury through enhancement of mitochondrial function and Parkin activity	23
FACI is a novel clathrin adaptor protein 2-binding protein that facilitates low-density lipoprotein endocytosis	23
AgRP mediated calcium Inhibition of feeding via the vagal afferent nerve-brain pathway	23
Identification of Gm15441, a Txnip antisense lncRNA, as a critical regulator in liver metabolic homeostasis	23
mTORC1-c-Myc pathway rewires methionine metabolism for HCC progression through suppressing SIRT4 mediated ADP ribosylation of MAT2A	23
Rapid and robust derivation of mesenchymal stem cells from human pluripotent stem cells via temporal induction of neuralized ectoderm	22
Genetic influences on the association between DNA methylation and obesity measures: insights from a twin study design	22
A polygenic risk score predicts mosaic loss of chromosome Y in circulating blood cells	22
Human skin dermis-derived fibroblasts are a kind of functional mesenchymal stromal cells: judgements from surface markers, biological characteristics, to therapeutic efficacy	22
CD24+LCN2+ liver progenitor cells in ductular reaction contributed to macrophage inflammatory responses in chronic liver injury	22
Gut microbial metabolite deoxycholic acid facilitates Th17 differentiation through modulating cholesterol biosynthesis and participates in high-fat diet-associated colonic inflammation	21
Neutrophil extracellular traps promote thrombogenicity in cerebral venous sinus thrombosis	21
YTHDF1 promotes breast cancer progression by facilitating FOXM1 translation in an m6A-dependent manner	21
Macrophages derived from pluripotent stem cells: prospective applications and research gaps	21
Autophagy induces hair follicle stem cell activation and hair follicle regeneration by regulating glycolysis	21
BRD4 inhibitor GNE987 exerts anti-cancer effects by targeting super-enhancers in neuroblastoma	21
Comparison of DNA targeting CRISPR editors in human cells	21
Enpp1 ameliorates MAFLD by regulating hepatocyte lipid metabolism through the AMPK/PPARα signaling pathway	21
Correction: RRM2 silencing suppresses malignant phenotype and enhances radiosensitivity via activating cGAS/STING signaling pathway in lung adenocarcinoma	20
SK3 in POMC neurons plays a sexually dimorphic role in energy and glucose homeostasis	20
Intranasal HD-Ad vaccine protects the upper and lower respiratory tracts of hACE2 mice against SARS-CoV-2	20
The lncRNA MIR181A1HG in extracellular vesicles derived from highly metastatic colorectal cancer cells promotes liver metastasis by remodeling the extracellular matrix and recruiting myeloid-derived s	20
A SNARE protective pool antagonizes APOL1 renal toxicity in Drosophila nephrocytes	20
MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning	20
A translational perspective of the malignant hematopoietic proteoglycome	20
Thyroid hormone receptor knockout prevents the loss of Xenopus tail regeneration capacity at metamorphic climax	20
A novel self-inhaled nicotine exposure system in murine models reveals age-dependent metabolic effects of nicotine	20
Biological function of RNA-binding proteins in myocardial infarction: a potential emerging therapeutic limelight	20
Predictive and prognostic biomarkers of bone metastasis in breast cancer: current status and future directions	19
Single-cell transcriptomic analysis of normal and pathological tissues from the same patient uncovers colon cancer progression	19
The SIRT7-mediated deacetylation of CHD1L amplifies HIF-2α-dependent signal that drives renal cell carcinoma progression and sunitinib resistance	19
Knockout of secretin ameliorates biliary and liver phenotypes during alcohol-induced hepatotoxicity	19
Intensity-dependent gamma electrical stimulation regulates microglial activation, reduces beta-amyloid load, and facilitates memory in a mouse model of Alzheimer’s disease	19
Unconventional protein post-translational modifications: the helmsmen in breast cancer	19
The two-faced role of ATF2 on cisplatin response in gastric cancer depends on p53 context	19
The integrin beta1 modulator Tirofiban prevents adipogenesis and obesity by the overexpression of integrin-linked kinase: a pre-clinical approach in vitro and in vivo	19
Comparison of characteristics and immune responses between paired human nasal and bronchial epithelial organoids	19
TSA-PACT: a method for tissue clearing and immunofluorescence staining on zebrafish brain with improved sensitivity, specificity and stability	19
The RNA binding protein CARHSP1 facilitates tumor growth, metastasis and immune escape by enhancing IL-17RA mRNA stabilization in prostate cancer	19
A novel function for α-synuclein as a regulator of NCK2 in olfactory bulb: implications for its role in olfaction	19
β-catenin mediates endodermal commitment of human ES cells via distinct transactivation functions	18
YBX1 mediates alternative splicing and maternal mRNA decay during pre-implantation development	18
Glycolysis-cholesterol metabolic axis in immuno-oncology microenvironment: emerging role in immune cells and immunosuppressive signaling	18
Circ_HUWE1: a novel regulator of lipid accumulation, inflammation, and gut microbiota in atherosclerosis	18
Bradykinin promotes immune responses in differentiated embryonic neurospheres carrying APPswe and PS1dE9 mutations	18
Multifunctional roles of γ-enolase in the central nervous system: more than a neuronal marker	18
Nanotechnological engineering of extracellular vesicles for the development of actively targeted hybrid nanodevices	18
Differential impact of BRAFV600E isoforms on tumorigenesis in a zebrafish model of melanoma	18

Exosomal USP13 derived from microvascular endothelial cells regulates immune microenvironment and improves functional recovery after spinal cord injury by stabilizing IκBα	18
l-Arginine, as an essential amino acid, is a potential substitute for treating COPD via regulation of ROS/NLRP3/NF-κB signaling pathway	18
Role of ammonia for brain abnormal protein glycosylation during the development of hepatitis B virus-related liver diseases	18
Novel roles for CREG1 in hematopoiesis revealed by single-cell RNA sequencing	18
Deubiquitinase USP10 promotes osteosarcoma autophagy and progression through regulating GSK3β-ULK1 axis	17
Reproductive chemical database: a curated database of chemicals that modulate protein targets regulating important reproductive biological processes	17
Polygenic risk scores of fasting insulin and insulin-related traits in a Taiwanese Han population	17
Dysregulated ac4C modification of mRNA in a mouse model of early-stage Alzheimer’s disease	17
Peptides targeting RAB11A–FIP2 complex inhibit HPIV3, RSV, and IAV replication as broad-spectrum antivirals	17
IFITM3 promotes malignant progression, cancer stemness and chemoresistance of gastric cancer by targeting MET/AKT/FOXO3/c-MYC axis	17
Antioxidant supplements promote tumor formation and growth and confer drug resistance in hepatocellular carcinoma by reducing intracellular ROS and induction of TMBIM1	17
Structural properties of immune complexes formed by viral antigens and specific antibodies shape the inflammatory response of macrophages	17
Development of a novel human CD147 knock-in NSG mouse model to test SARS-CoV-2 viral infection	17
Tunable PhenoCycler imaging of the murine pre-clinical tumour microenvironments	17
Common immunopathogenesis of central nervous system diseases: the protein-homeostasis-system hypothesis	17
Single‑cell RNA sequencing analysis of human embryos from the late Carnegie to fetal development	17
The promoting effects of activated olfactory ensheathing cells on angiogenesis after spinal cord injury through the PI3K/Akt pathway	17
A distinct circular DNA profile intersects with proteome changes in the genotoxic stress-related hSOD1G93A model of ALS	17
Timely expression of PGAM5 and its cleavage control mitochondrial homeostasis during neurite re-growth after traumatic brain injury	17
Targeting miR-181a/b in retinitis pigmentosa: implications for disease progression and therapy	17
Ontogeny of RORγt+ cells in the intestine of newborns and its role in the development of experimental necrotizing enterocolitis	17
Meloxicam inhibits STING phosphorylation and alleviates intracellular DNA-mediated autoimmune responses	16
Retraction Note: The suppressing role of miR-622 in renal cell carcinoma progression by down-regulation of CCL18/MAPK signal pathway	16
Mitochondrial transfer/transplantation: an emerging therapeutic approach for multiple diseases	16
Predictive biomarkers for the responsiveness of recurrent glioblastomas to activated killer cell immunotherapy	16
Transcription factor E4F1 dictates spermatogonial stem cell fate decisions by regulating mitochondrial functions and cell cycle progression	16
In vivo genome-wide CRISPR screening identifies ZNF24 as a negative NF-κB modulator in lung cancer	16
Oncogenic activation revealed by FGFR2 genetic alterations in intrahepatic cholangiocarcinomas	16
Intermittent hypoxia in a mouse model of apnea of prematurity leads to a retardation of cerebellar development and long-term functional deficits	16
Histone deacetylase 3 facilitates TNFα-mediated NF-κB activation through suppressing CTSB induced RIP1 degradation and is required for host defense against bacterial infection	16
Revisiting potential value of antitumor drugs in the treatment of COVID-19	16
DNA damage response and cell fate decisions across the lifespan: from fetal development to age-related respiratory diseases	16
The versatile roles of testrapanins in cancer from intracellular signaling to cell–cell communication: cell membrane proteins without ligands	16
Angiopoietin-like protein 8 orchestrates macrophage glycogen metabolism and polarization via the JNK signaling pathway in cytokine storm syndrome	16
Human epicardial organoids from pluripotent stem cells resemble fetal stage with potential cardiomyocyte- transdifferentiation	15
Generation of mitochondria-rich kidney organoids from expandable intermediate mesoderm progenitors reprogrammed from human urine cells under defined medium	15
Overview of the meningeal lymphatic vessels in aging and central nervous system disorders	15
Golgiphagy: a novel selective autophagy to the fore	15
NUAK1 coordinates growth factor-dependent activation of mTORC2 and Akt signaling	15
The relationship between abnormal glucose metabolism and chronic pain	15
Chemical screen in zebrafish lateral line identified compounds that ameliorate neomycin-induced ototoxicity by inhibiting ferroptosis pathway	15
The balance between NANOG and SOX17 mediated by TET proteins regulates specification of human primordial germ cell fate	15
CrebH protects against liver injury associated with colonic inflammation via modulation of exosomal miRNA	15
Astaxanthin attenuates glucose-induced liver injury in largemouth bass: role of p38MAPK and PI3K/Akt signaling pathways	15
PFKFB3 in neovascular eye disease: unraveling mechanisms and exploring therapeutic strategies	15
Concurrent mapping of multiple epigenetic marks and co-occupancy using ACT2-seq	15