Cell and Bioscience

Article	Citations
Tick-borne encephalitis affects sleep–wake behavior and locomotion in infant rats	175
Generation of musculoskeletal cells from human urine epithelium-derived presomitic mesoderm cells	150
Correction: Plasma metabolomics provides new insights into the relationship between metabolites and outcomes and left ventricular remodeling of coronary artery disease	139
Retraction Note: Growth inhibition and apoptosis in colorectal cancer cells induced by vitamin D-Nanoemulsion (NVD): involvement of Wnt/β-catenin and other signal transduction pathways	117
Microvascular destabilization and intricated network of the cytokines in diabetic retinopathy: from the perspective of cellular and molecular components	115
Brain nuclear receptors and cardiovascular function	103
Autophagy-mediated degradation of NOTCH1 intracellular domain controls the epithelial to mesenchymal transition and cancer metastasis	101
PI3K-AKT activation resculpts integrin signaling to drive filamentous tau-induced proinflammatory astrogliosis	94
Integrating spatial transcriptomics with single-cell transcriptomics reveals a spatiotemporal gene landscape of the human developing kidney	87
Single-cell genomics identifies distinct B1 cell developmental pathways and reveals aging-related changes in the B-cell receptor repertoire	79
Sperm-borne small non-coding RNAs: potential functions and mechanisms as epigenetic carriers	76
Metabolic reprogramming in colorectal cancer: regulatory networks and therapy	76
Transcriptome-scale spatial gene expression in rat arcuate nucleus during puberty	69
Genome-wide association study of the fatty liver index in the Taiwanese population reveals shared and population-specific genetic risk factors across ethnicities	67
Integrative analysis of bulk and single-cell RNA sequencing reveals the gene expression profile and the critical signaling pathways of type II CPAM	64
Clinical biomarkers for Lewy body diseases	63
Neurokinin-2 receptor negatively modulates substance P responses by forming complex with Neurokinin-1 receptor	59
Slit-Robo expression in the leech nervous system: insights into eyespot evolution	54
Retraction Note: LncRNA SNHG7 promotes pancreatic cancer proliferation through ID4 by sponging miR-342-3p	52
Bromodomain proteins as potential therapeutic targets for B-cell non-Hodgkin lymphoma	50
Comparative proteomic profiling of plasma exosomes in lung cancer cases of liver and brain metastasis	50
HBx promotes tumorigenicity through RRM2-mediated autophagy in hepatocellular carcinoma	47
Modulation of foraging-like behaviors by cholesterol-FGF19 axis	45
Long-term maintenance of human endometrial epithelial stem cells and their therapeutic effects on intrauterine adhesion	45
Electric field stimulation boosts neuronal differentiation of neural stem cells for spinal cord injury treatment via PI3K/Akt/GSK-3β/β-catenin activation	44

Multi-omics in thoracic aortic aneurysm: the complex road to the simplification	44
A new thinking: deciphering the aberrance and clinical implication of copper-death signatures in clear cell renal cell carcinoma	44
Calcineurin inhibition protects against dopamine toxicity and attenuates behavioral decline in a Parkinson’s disease model	43
Precision nephrotoxicity testing using 3D in vitro models	43
RNA sequencing profiles reveal dynamic signaling and glucose metabolic features during bone marrow mesenchymal stem cell senescence	42
Neural EGFL-like 1, a craniosynostosis-related osteochondrogenic molecule, strikingly associates with neurodevelopmental pathologies	42
New insights into the stromal interaction molecule 2 function and its impact on the immunomodulation of tumor microenvironment	42
PGCLCs of human 45,XO reveal pathogenetic pathways of neurocognitive and psychosocial disorders	39
SIRT6 deficiency impairs the deacetylation and ubiquitination of UHRF1 to strengthen glycolysis and lactate secretion in bladder cancer	39
Sex-specific hypothalamic neuropathology and glucose metabolism in an amyloidosis transgenic mouse model of Alzheimer’s disease	39
DNA methyltransferase 1 knockdown reverses PTEN and VDR by mediating demethylation of promoter and protects against renal injuries in hepatitis B virus-associated glomerulonephritis	38
SARS-CoV-2 variants divergently infect and damage cardiomyocytes in vitro and in vivo	38
Hypofucosylation of Unc5b regulated by Fut8 enhances macrophage emigration and prevents atherosclerosis	38
The nerve growth factor-delivered signals in prostate cancer and its associated microenvironment: when the dialogue replaces the monologue	37
Single-cell analysis of mouse uterus at the invasion phase of embryo implantation	37
A patient-derived mutation of epilepsy-linked LGI1 increases seizure susceptibility through regulating Kv1.1	36
Clostridium butyricum regulates intestinal barrier function via trek1 to improve behavioral abnormalities in mice with autism spectrum disorder	36
The cGAS-STING pathway in cardiovascular diseases: from basic research to clinical perspectives	36
Targeting G-quadruplex for rescuing impaired chondrogenesis in WRN-deficient stem cells	36
Autophagy deficiency in neurodevelopmental disorders	34
Fibroblast-to-cardiomyocyte lactate shuttle modulates hypertensive cardiac remodelling	34
BVES is a novel interactor of ANO5 and regulates myoblast differentiation	33
Modeling of the brain-lung axis using organoids in traumatic brain injury: an updated review	33
Influence of miR-221/222 on cardiomyocyte calcium handling and function	33
Current methodologies in protein ubiquitination characterization: from ubiquitinated protein to ubiquitin chain architecture	33
The phosphorylation to acetylation/methylation cascade in transcriptional regulation: how kinases regulate transcriptional activities of DNA/histone-modifying enzymes	32
Regulation of telomerase towards tumor therapy	32
Uncoupling p38α nuclear and cytoplasmic functions and identification of two p38α phosphorylation sites on β-catenin: implications for the Wnt signaling pathway in CRC models	32
Insight into the mitochondrial unfolded protein response and cancer: opportunities and challenges	32
CircRNA Itm2b induces oxidative stress via the interaction with Sirt1-Nox4 to aggravate sleep disturbances after traumatic brain injury	32
TRIM22 suppresses Zika virus replication by targeting NS1 and NS3 for proteasomal degradation	32
Umbelliferone and eriodictyol suppress the cellular entry of SARS-CoV-2	32
Hippocampal CA1 neuron, a crucial regulator for chronic stress exacerbating Alzheimer’s disease progression	32
Editorial Expression of Concern: Ginkgetin aglycone ameliorates LPS-induced acute kidney injury by activating SIRT1 via inhibiting the NF-κB signaling pathway	32
Programmed cell death in the cognitive impairment of obstructive sleep apnea	31
NAD+ metabolism-based immunoregulation and therapeutic potential	30
The multifaceted therapeutic value of targeting steroid receptor coactivator-1 in tumorigenesis	30
Transcriptomic characterization of tissues from patients and subsequent pathway analyses reveal biological pathways that are implicated in spastic ataxia	29
DNA in extracellular vesicles: from evolution to its current application in health and disease	29
CXCL11 reprograms M2-biased macrophage polarization to alleviate pulmonary fibrosis in mice	29
Dynamic single-cell RNA-seq analysis reveals distinct tumor program associated with microenvironmental remodeling and drug sensitivity in multiple myeloma	29
Hypoxia increases RCC stem cell phenotype via altering the androgen receptor (AR)-lncTCFL5-2-YBX1-SOX2 signaling axis	29
ER Ca2+ overload activates the IRE1α signaling and promotes cell survival	29
Inhibition of sphingolipid metabolism in osteosarcoma protects against CD151-mediated tumorigenicity	28
A synthetic pregnenolone analog promotes microtubule dynamics and neural development	28
Inhibition of PI3 kinase isoform p110α suppresses neuroblastoma growth and induces the reduction of Anaplastic Lymphoma Kinase	27
Chemically defined and xeno-free media enables the derivation of human extended pluripotent stem cell lines from discarded blastocysts with a high efficiency	27
Alkylglycerol monooxygenase represses prostanoid biosynthesis in a sex-dependent manner	27
Unraveling the serotonin saga: from discovery to weight regulation and beyond - a comprehensive scientific review	26
Macrophage-derived exosomes mediate glomerular endothelial cell dysfunction in sepsis-associated acute kidney injury	26

Cutting-edge advances in modeling the blood–brain barrier and tools for its reversible permeabilization for enhanced drug delivery into the brain	26
Rab11a-dependent recycling of Glut3 inhibits seizure-induced neuronal disulfidptosis by alleviating glucose deficiency	26
Exosomes originating from infection with the cytoplasmic single-stranded RNA virus Rift Valley fever virus (RVFV) protect recipient cells by inducing RIG-I mediated IFN-B response that leads to activa	26
ISG15 suppresses ovulation and female fertility by ISGylating ADAMTS1	26
A cost-effective machine learning-based method for preeclampsia risk assessment and driver genes discovery	26
Coffee as a dietary strategy to prevent SARS-CoV-2 infection	26
Nrf2 is predominantly expressed in hippocampal neurons in a rat model of temporal lobe epilepsy	26
ANGPTL2 binds MAG to efficiently enhance oligodendrocyte differentiation	26
Advancing equity through strengthening research on health and well-being of Asian American, Native Hawaiian, and Pacific Islander	25
The eukaryotic initiation factor 5A (eIF5A1), the molecule, mechanisms and recent insights into the pathophysiological roles	25
Multiple functions of autophagy in vascular calcification	25
Discovery and mechanism studies of a novel ATG4B inhibitor Ebselen by drug repurposing and its anti-colorectal cancer effects in mice	25
Structural basis of human PRPS2 filaments	25
Therapeutic uses of oxytocin in stress-related neuropsychiatric disorders	24
Astrocyte derived TSP2 contributes to synaptic alteration and visual dysfunction in retinal ischemia/reperfusion injury	24
The immunological mechanisms and therapeutic potential in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity	24
The regulatory mechanism of neutrophil extracellular traps in cancer biological behavior	24
Mutation-class dependent signatures outweigh disease-associated processes in cystic fibrosis cells	24
The RBM39 degrader indisulam inhibits acute megakaryoblastic leukemia by altering the alternative splicing of ZMYND8	24
Damage mechanism and therapy progress of the blood-brain barrier after ischemic stroke	24
V1bR enhances glucose-stimulated insulin secretion by paracrine production of glucagon which activates GLP-1 receptor	23
TAZ deficiency exacerbates psoriatic pathogenesis by increasing the histamine-releasing factor	23
SETD8, a frequently mutated gene in cervical cancer, enhances cisplatin sensitivity by impairing DNA repair	23
GSTM2 alleviates heart failure by inhibiting DNA damage in cardiomyocytes	23
Integrated single-nucleus sequencing and spatial architecture analysis identified distinct injured-proximal tubular types in calculi rats	23
DNA methylation of ACADS promotes immunogenic cell death in hepatocellular carcinoma	23
Bone morphogenetic protein signaling regulation of AMPK and PI3K in lung cancer cells and C. elegans	22
Knocking out Fkbp51 decreases CCl4-induced liver injury through enhancement of mitochondrial function and Parkin activity	22
PRCC reduces the sensitivity of cancer cells to DNA damage by inhibiting JNK and ATM/ATR pathways and results in a poor prognosis in hepatocellular carcinoma	22
Enpp1 ameliorates MAFLD by regulating hepatocyte lipid metabolism through the AMPK/PPARα signaling pathway	22
Klotho exerts protection in chronic kidney disease associated with regulating inflammatory response and lipid metabolism	22
Gut microbial metabolite deoxycholic acid facilitates Th17 differentiation through modulating cholesterol biosynthesis and participates in high-fat diet-associated colonic inflammation	22
AgRP mediated calcium Inhibition of feeding via the vagal afferent nerve-brain pathway	21
CD24+LCN2+ liver progenitor cells in ductular reaction contributed to macrophage inflammatory responses in chronic liver injury	21
Neutrophil extracellular traps promote thrombogenicity in cerebral venous sinus thrombosis	21
Canonical and non-canonical functions of the non-coding RNA component (TERC) of telomerase complex	21
A polygenic risk score predicts mosaic loss of chromosome Y in circulating blood cells	21
Comparison of DNA targeting CRISPR editors in human cells	21
Rapid and robust derivation of mesenchymal stem cells from human pluripotent stem cells via temporal induction of neuralized ectoderm	21
Human skin dermis-derived fibroblasts are a kind of functional mesenchymal stromal cells: judgements from surface markers, biological characteristics, to therapeutic efficacy	21
Macrophages derived from pluripotent stem cells: prospective applications and research gaps	20
BRD4 inhibitor GNE987 exerts anti-cancer effects by targeting super-enhancers in neuroblastoma	20
FACI is a novel clathrin adaptor protein 2-binding protein that facilitates low-density lipoprotein endocytosis	20
Genetic influences on the association between DNA methylation and obesity measures: insights from a twin study design	20
YTHDF1 promotes breast cancer progression by facilitating FOXM1 translation in an m6A-dependent manner	20
Identification of Gm15441, a Txnip antisense lncRNA, as a critical regulator in liver metabolic homeostasis	19
The lncRNA MIR181A1HG in extracellular vesicles derived from highly metastatic colorectal cancer cells promotes liver metastasis by remodeling the extracellular matrix and recruiting myeloid-derived s	19
A translational perspective of the malignant hematopoietic proteoglycome	19
Autophagy induces hair follicle stem cell activation and hair follicle regeneration by regulating glycolysis	19
Intensity-dependent gamma electrical stimulation regulates microglial activation, reduces beta-amyloid load, and facilitates memory in a mouse model of Alzheimer’s disease	19
mTORC1-c-Myc pathway rewires methionine metabolism for HCC progression through suppressing SIRT4 mediated ADP ribosylation of MAT2A	19
SK3 in POMC neurons plays a sexually dimorphic role in energy and glucose homeostasis	19
Predictive and prognostic biomarkers of bone metastasis in breast cancer: current status and future directions	19
Unconventional protein post-translational modifications: the helmsmen in breast cancer	18
A SNARE protective pool antagonizes APOL1 renal toxicity in Drosophila nephrocytes	18
Comparison of characteristics and immune responses between paired human nasal and bronchial epithelial organoids	18
Correction: RRM2 silencing suppresses malignant phenotype and enhances radiosensitivity via activating cGAS/STING signaling pathway in lung adenocarcinoma	18
Thyroid hormone receptor knockout prevents the loss of Xenopus tail regeneration capacity at metamorphic climax	18
MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning	18
The SIRT7-mediated deacetylation of CHD1L amplifies HIF-2α-dependent signal that drives renal cell carcinoma progression and sunitinib resistance	18
The RNA binding protein CARHSP1 facilitates tumor growth, metastasis and immune escape by enhancing IL-17RA mRNA stabilization in prostate cancer	18
Intranasal HD-Ad vaccine protects the upper and lower respiratory tracts of hACE2 mice against SARS-CoV-2	18
Metabolic reprogramming and metabolic sensors in KSHV-induced cancers and KSHV infection	18
TSA-PACT: a method for tissue clearing and immunofluorescence staining on zebrafish brain with improved sensitivity, specificity and stability	18
Epigallocatechin gallate from green tea effectively blocks infection of SARS-CoV-2 and new variants by inhibiting spike binding to ACE2 receptor	18
β-catenin mediates endodermal commitment of human ES cells via distinct transactivation functions	18
Biological function of RNA-binding proteins in myocardial infarction: a potential emerging therapeutic limelight	18
Single-cell transcriptomic analysis of normal and pathological tissues from the same patient uncovers colon cancer progression	18
The two-faced role of ATF2 on cisplatin response in gastric cancer depends on p53 context	17
Differential impact of BRAFV600E isoforms on tumorigenesis in a zebrafish model of melanoma	17
A novel function for α-synuclein as a regulator of NCK2 in olfactory bulb: implications for its role in olfaction	17
Nanotechnological engineering of extracellular vesicles for the development of actively targeted hybrid nanodevices	17
Novel roles for CREG1 in hematopoiesis revealed by single-cell RNA sequencing	17
Exosomal USP13 derived from microvascular endothelial cells regulates immune microenvironment and improves functional recovery after spinal cord injury by stabilizing IκBα	17
Role of ammonia for brain abnormal protein glycosylation during the development of hepatitis B virus-related liver diseases	17
Glycolysis-cholesterol metabolic axis in immuno-oncology microenvironment: emerging role in immune cells and immunosuppressive signaling	17
Deubiquitinase USP10 promotes osteosarcoma autophagy and progression through regulating GSK3β-ULK1 axis	17
YBX1 mediates alternative splicing and maternal mRNA decay during pre-implantation development	17
Multifunctional roles of γ-enolase in the central nervous system: more than a neuronal marker	17
Bradykinin promotes immune responses in differentiated embryonic neurospheres carrying APPswe and PS1dE9 mutations	17

Knockout of secretin ameliorates biliary and liver phenotypes during alcohol-induced hepatotoxicity	17
The promoting effects of activated olfactory ensheathing cells on angiogenesis after spinal cord injury through the PI3K/Akt pathway	17
The integrin beta1 modulator Tirofiban prevents adipogenesis and obesity by the overexpression of integrin-linked kinase: a pre-clinical approach in vitro and in vivo	17
Antioxidant supplements promote tumor formation and growth and confer drug resistance in hepatocellular carcinoma by reducing intracellular ROS and induction of TMBIM1	17
l-Arginine, as an essential amino acid, is a potential substitute for treating COPD via regulation of ROS/NLRP3/NF-κB signaling pathway	17
Revisiting potential value of antitumor drugs in the treatment of COVID-19	16
Targeting miR-181a/b in retinitis pigmentosa: implications for disease progression and therapy	16
Tunable PhenoCycler imaging of the murine pre-clinical tumour microenvironments	16
Structural properties of immune complexes formed by viral antigens and specific antibodies shape the inflammatory response of macrophages	16
Common immunopathogenesis of central nervous system diseases: the protein-homeostasis-system hypothesis	16
Transcription factor E4F1 dictates spermatogonial stem cell fate decisions by regulating mitochondrial functions and cell cycle progression	16
Ontogeny of RORγt+ cells in the intestine of newborns and its role in the development of experimental necrotizing enterocolitis	16
Reproductive chemical database: a curated database of chemicals that modulate protein targets regulating important reproductive biological processes	16
Peptides targeting RAB11A–FIP2 complex inhibit HPIV3, RSV, and IAV replication as broad-spectrum antivirals	16
The versatile roles of testrapanins in cancer from intracellular signaling to cell–cell communication: cell membrane proteins without ligands	15
A distinct circular DNA profile intersects with proteome changes in the genotoxic stress-related hSOD1G93A model of ALS	15
IFITM3 promotes malignant progression, cancer stemness and chemoresistance of gastric cancer by targeting MET/AKT/FOXO3/c-MYC axis	15
Mitochondrial transfer/transplantation: an emerging therapeutic approach for multiple diseases	15
CrebH protects against liver injury associated with colonic inflammation via modulation of exosomal miRNA	15
Timely expression of PGAM5 and its cleavage control mitochondrial homeostasis during neurite re-growth after traumatic brain injury	15
Dysregulated ac4C modification of mRNA in a mouse model of early-stage Alzheimer’s disease	15
Intermittent hypoxia in a mouse model of apnea of prematurity leads to a retardation of cerebellar development and long-term functional deficits	15
NUAK1 coordinates growth factor-dependent activation of mTORC2 and Akt signaling	15
Human epicardial organoids from pluripotent stem cells resemble fetal stage with potential cardiomyocyte- transdifferentiation	15
Meloxicam inhibits STING phosphorylation and alleviates intracellular DNA-mediated autoimmune responses	15
Histone deacetylase 3 facilitates TNFα-mediated NF-κB activation through suppressing CTSB induced RIP1 degradation and is required for host defense against bacterial infection	15
Development of a novel human CD147 knock-in NSG mouse model to test SARS-CoV-2 viral infection	15
Predictive biomarkers for the responsiveness of recurrent glioblastomas to activated killer cell immunotherapy	15
Concurrent mapping of multiple epigenetic marks and co-occupancy using ACT2-seq	15
Single‑cell RNA sequencing analysis of human embryos from the late Carnegie to fetal development	15
Retraction Note: The suppressing role of miR-622 in renal cell carcinoma progression by down-regulation of CCL18/MAPK signal pathway	14
Oncogenic activation revealed by FGFR2 genetic alterations in intrahepatic cholangiocarcinomas	14
Astaxanthin attenuates glucose-induced liver injury in largemouth bass: role of p38MAPK and PI3K/Akt signaling pathways	14
Chemical screen in zebrafish lateral line identified compounds that ameliorate neomycin-induced ototoxicity by inhibiting ferroptosis pathway	14
GLUT1-mediated microglial proinflammatory activation contributes to the development of stress-induced spatial learning and memory dysfunction in mice	14
Maladaptive changes in the homeostasis of AEA-TRPV1/CB1R induces pain-related hyperactivity of nociceptors after spinal cord injury	14
The role of long noncoding RNAs in ocular angiogenesis and vascular oculopathy	14
In vivo genome-wide CRISPR screening identifies ZNF24 as a negative NF-κB modulator in lung cancer	14
Functions and mechanisms of protein disulfide isomerase family in cancer emergence	14
PFKFB3 in neovascular eye disease: unraveling mechanisms and exploring therapeutic strategies	14
Overview of the meningeal lymphatic vessels in aging and central nervous system disorders	14
Phosphorylation at tyrosine 317 and 508 are crucial for PIK3CA/p110α to promote CRC tumorigenesis	14
ADAMTS-1: a novel target gene of an estrogen-induced transcription factor, EGR1, critical for embryo implantation in the mouse uterus	14
Golgiphagy: a novel selective autophagy to the fore	14
Activation of Piezo1 downregulates renin in juxtaglomerular cells and contributes to blood pressure homeostasis	14
Activation of arcuate nucleus glucagon-like peptide-1 receptor-expressing neurons suppresses food intake	14
The relationship between abnormal glucose metabolism and chronic pain	14
Generation of mitochondria-rich kidney organoids from expandable intermediate mesoderm progenitors reprogrammed from human urine cells under defined medium	14
Interaction of TAGLN and USP1 promotes ZEB1 ubiquitination degradation in UV-induced skin photoaging	14
Spatiotemporal control of genome engineering in cone photoreceptors	14
The balance between NANOG and SOX17 mediated by TET proteins regulates specification of human primordial germ cell fate	14