OOIR: Observatory of International Research

Papers

(The H4-Index of Fluids and Barriers of the Cns is 30. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
A scoping review of the discrepancies in the measurement of cerebral blood flow in idiopathic intracranial hypertension: oligemia, euvolemia or hyperemia?	154
The effects of dose, valency, and affinity on TfR-mediated brain delivery in vivo	144
miRNA-ome plasma analysis unveils changes in blood–brain barrier integrity associated with acute liver failure in rats	84
The hypervirulent Group B Streptococcus HvgA adhesin promotes central nervous system invasion through transcellular crossing of the choroid plexus	74
CSF hyperdynamics in rats mimicking the obesity and androgen excess characteristic of patients with idiopathic intracranial hypertension	71
Commentary on “Structural characterization of SLYM – a 4th meningeal membrane”	62
BOLD-CSF dynamics assessed using real-time phase contrast CSF flow interleaved with cortical BOLD MRI	61
Oxidative stress alters mitochondrial homeostasis in isolated brain capillaries	61
A human pluripotent stem cell-derived in vitro model of the blood–brain barrier in cerebral malaria	56
Reactive astrocyte-derived exosomes enhance intracranial lymphatic drainage in mice after intracranial hemorrhage	56
Estimates of the permeability of extra-cellular pathways through the astrocyte endfoot sheath	50
Age, dose, and binding to TfR on blood cells influence brain delivery of a TfR-transported antibody	49
The proteome of the blood–brain barrier in rat and mouse: highly specific identification of proteins on the luminal surface of brain microvessels by in vivo glycocapture	48
Ex vivo nanoscale abluminal mapping of putative cargo receptors at the blood-brain barrier of expanded brain capillaries	46
Claudin-5a is essential for the functional formation of both zebrafish blood-brain barrier and blood-cerebrospinal fluid barrier	41
High affinity of β-amyloid proteins to cerebral capillaries: implications in chronic lead exposure-induced neurotoxicity in rats	41
Evaluation of CSF albumin quotient in neuronal surface antibody-associated autoimmune encephalitis	40
Next-generation in vitro blood–brain barrier models: benchmarking and improving model accuracy	36
Comparative analysis of hippocampal extracellular space uncovers widely altered peptidome upon epileptic seizure in urethane-anaesthetized rats	36
Prolonged culturing of iPSC-derived brain endothelial-like cells is associated with quiescence, downregulation of glycolysis, and resistance to disruption by an Alzheimer’s brain milieu	34
Isolation method of brain microvessels from small frozen human brain tissue for blood-brain barrier protein expression analysis	34
Impact of age on the cerebrospinal fluid spaces: high-convexity and medial subarachnoid spaces decrease with age	34
Identification of key molecular biomarkers involved in reactive and neurodegenerative processes present in inherited congenital hydrocephalus	33
Rh-relaxin-2 attenuates oxidative stress and neuronal apoptosis via ERK-nNOS-NO pathway after germinal matrix hemorrhage in rats	33
Ependymal cilia decline and AQP4 upregulation in young adult rats with syringomyelia	32

Concentration gradients of monoamines, their precursors and metabolites in serial lumbar cerebrospinal fluid of neurologically healthy patients determined with a novel LC–MS/MS technique	31
Cerebrospinal fluid biomarkers that reflect clinical symptoms in idiopathic normal pressure hydrocephalus patients	30
Elevated CSF inflammatory markers in patients with idiopathic normal pressure hydrocephalus do not promote NKCC1 hyperactivity in rat choroid plexus	30
Recapitulation of physiologic and pathophysiologic pulsatile CSF flow in purpose-built high-throughput hydrocephalus bioreactors	30
Active CNS delivery of oxycodone in healthy and endotoxemic pigs	30