OOIR: Observatory of International Research

Papers

(The H4-Index of Fluids and Barriers of the Cns is 33. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Bridging regional neurovascular unit heterogeneity and cognitive function: a review	212
miRNA-ome plasma analysis unveils changes in blood–brain barrier integrity associated with acute liver failure in rats	185
A scoping review of the discrepancies in the measurement of cerebral blood flow in idiopathic intracranial hypertension: oligemia, euvolemia or hyperemia?	113
CSF hyperdynamics in rats mimicking the obesity and androgen excess characteristic of patients with idiopathic intracranial hypertension	104
The hypervirulent Group B Streptococcus HvgA adhesin promotes central nervous system invasion through transcellular crossing of the choroid plexus	85
The effects of dose, valency, and affinity on TfR-mediated brain delivery in vivo	83
The proteome of the blood–brain barrier in rat and mouse: highly specific identification of proteins on the luminal surface of brain microvessels by in vivo glycocapture	80
BOLD-CSF dynamics assessed using real-time phase contrast CSF flow interleaved with cortical BOLD MRI	78
Age, dose, and binding to TfR on blood cells influence brain delivery of a TfR-transported antibody	75
Ex vivo nanoscale abluminal mapping of putative cargo receptors at the blood-brain barrier of expanded brain capillaries	63
A human pluripotent stem cell-derived in vitro model of the blood–brain barrier in cerebral malaria	56
Translational biomarkers of hypoxic brain injury uncovered in CSF secreting human choroid plexus organoids	56
Effect of intracerebral infusion rate on optic nerve tissue pressure and diurnal intracranial pressure in rats	55
Commentary on “Structural characterization of SLYM – a 4th meningeal membrane”	54
Estimates of the permeability of extra-cellular pathways through the astrocyte endfoot sheath	51
White matter lesions associated with the reemergence of grasp reflexes in patients with idiopathic normal pressure hydrocephalus	50
High affinity of β-amyloid proteins to cerebral capillaries: implications in chronic lead exposure-induced neurotoxicity in rats	47
Oxidative stress alters mitochondrial homeostasis in isolated brain capillaries	47
Claudin-5a is essential for the functional formation of both zebrafish blood-brain barrier and blood-cerebrospinal fluid barrier	45
Reactive astrocyte-derived exosomes enhance intracranial lymphatic drainage in mice after intracranial hemorrhage	44
Relationships between measures of neurovascular integrity and fluid transport in aging: a multi-modal neuroimaging study	42
Comparative analysis of hippocampal extracellular space uncovers widely altered peptidome upon epileptic seizure in urethane-anaesthetized rats	41
Evidence for reduced choroid plexus volume in the aged brain	41
Concentration gradients of monoamines, their precursors and metabolites in serial lumbar cerebrospinal fluid of neurologically healthy patients determined with a novel LC–MS/MS technique	40
Neutrophil extracellular traps aggravate blood-brain barrier disruption via ZBP1/FSP1-mediated ferroptosis after traumatic brain injury	39

Rh-relaxin-2 attenuates oxidative stress and neuronal apoptosis via ERK-nNOS-NO pathway after germinal matrix hemorrhage in rats	39
Isolation method of brain microvessels from small frozen human brain tissue for blood-brain barrier protein expression analysis	36
Ependymal cilia decline and AQP4 upregulation in young adult rats with syringomyelia	36
Impact of age on the cerebrospinal fluid spaces: high-convexity and medial subarachnoid spaces decrease with age	35
Evaluation of CSF albumin quotient in neuronal surface antibody-associated autoimmune encephalitis	35
Ptpn20 deletion in H-Tx rats enhances phosphorylation of the NKCC1 cotransporter in the choroid plexus: an evidence of genetic risk for hydrocephalus in an experimental study	34
Prolonged culturing of iPSC-derived brain endothelial-like cells is associated with quiescence, downregulation of glycolysis, and resistance to disruption by an Alzheimer’s brain milieu	34
A budget for brain metabolic water production by glucose catabolism during rest, rises in activity and sleep	34