Open Biology

Papers
(The median citation count of Open Biology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)
ArticleCitations
Oxidized phospholipid damage signals as modulators of immunity159
RNF4 and USP7 cooperate in ubiquitin-regulated steps of DNA replication112
A short perinuclear amphipathic α-helix in Apq12 promotes nuclear pore complex biogenesis78
Retraction: ‘HOXD-AS1 confers cisplatin resistance in gastric cancer through epigenetically silencing PDCD4 via recruiting EZH2’ (2019), by Ye et al.76
Decoding life's inner workings: advances in quantitative bioimaging69
Comparative mitogenomic analysis and phylogeny of Veneridae with doubly uniparental inheritance53
Limitations of sequence dissimilarity as a predictor of prokaryotic lineage49
Visualization of sympathetic neural innervation in human white adipose tissue49
Into the second decade45
Correction to: ‘Unravelling nicotinic receptor and ligand features underlying neonicotinoid knockdown actions on the malaria vector mosquito Anopheles gambiae ’ (2024), 44
Intrinsically disordered proteins: modes of binding with emphasis on disordered domains43
MYH7 R453C induced cardiac remodelling via activating TGF-β/Smad2/3, ERK1/2 and Nox4/ROS/NF-κB signalling pathways42
Class II transactivator induces expression of MHC-I and MHC-II in transmissible Tasmanian devil facial tumours41
Nutrient-sensitive protein O-GlcNAcylation shapes daily biological rhythms41
Can calmodulin bind to lipids of the cytosolic leaflet of plasma membranes?40
SID-2 is a conserved extracellular vesicle protein that is not associated with environmental RNAi in parasitic nematodes38
Integrative analysis of genomic and transcriptomic alterations of AGR2 and AGR3 in cancer37
SLMAP3 is crucial for organogenesis through mechanisms involving primary cilia formation36
Risk factors for severe COVID-19 disease increase SARS-CoV-2 infectivity of endothelial cells and pericytes36
Primary brain cell infection by Toxoplasma gondii reveals the extent and dynamics of parasite differentiation and its impact on neuron biology36
Identification and characterization of host miRNAs that target the mouse mammary tumour virus (MMTV) genome36
NDUFS3 knockout cancer cells and molecular docking reveal specificity and mode of action of anti-cancer respiratory complex I inhibitors35
From the divergence of senescent cell fates to mechanisms and selectivity of senolytic drugs35
Min oscillations in bacteria as real-time reporter of environmental challenges at the single-cell level34
Palbociclib-mediated cell cycle arrest can occur in the absence of the CDK inhibitors p21 and p2733
The first genetic engineered system for ovothiol biosynthesis in diatoms reveals a mitochondrial localization for the sulfoxide synthase OvoA33
Every good biologist deserves favour32
Essential roles of the nucleolus during early embryonic development: a regulatory hub for chromatin organization32
Retraction: ‘Long non-coding RNA LINC00152 promotes gallbladder cancer metastasis and epithelial-mesenchymal transition by regulating HIF-1α via miR-138’32
Complement receptor 3-dependent engagement by Candida glabrata β-glucan modulates dendritic cells to induce regulatory T-cell expansion31
Arabidopsis thaliana endonuclease V is a ribonuclease specific for inosine-containing single-stranded RNA31
Modelling T-cell immunity against hepatitis C virus with liver organoids in a microfluidic coculture system29
A new view of axon growth and guidance grounded in the stochastic dynamics of actin networks28
Transiently restricting individual amino acids protects Drosophila melanogaster against multiple stressors28
Zebrafish reveal new roles for Fam83f in hatching and the DNA damage-mediated autophagic response27
Pleiotropic effects on proliferation and mineralization of primary human adipose tissue-derived stromal cells induced by simvastatin27
Correction to ‘Exaggerated trans-membrane charge of ammonium transporters in nutrient-poor marine environments’ (2022) by Kellom et al .27
Structure and in silico simulations of a cold-active esterase reveals its prime cold-adaptation mechanism26
Footprints in the Sno: investigating the cellular and molecular mechanisms of SNORD11625
The role of α-sheet structure in amyloidogenesis: characterization and implications24
A fast-growing dengue virus mutant reveals a dual role of STING in response to infection24
Pck2 association with the plasma membrane and efficient response of the cell integrity pathway require regulation of PI4P homeostasis by exomer24
In vitro reconstitution of substrate S-acylation by the zDHHC family of protein acyltransferases24
Retraction: ‘Long non-coding RNA LINC00346 contributes to cisplatin resistance in nasopharyngeal carcinoma by repressing miR-342-5p’ (2020), by Cui et al.24
Cigarette smoke-induced oxidative stress activates NRF2 to mediate fibronectin disorganization in vascular formation23
Unravelling nicotinic receptor and ligand features underlying neonicotinoid knockdown actions on the malaria vector mosquito Anopheles gambiae23
Au naturale: use of biologically derived cyclic di-nucleotides for cancer immunotherapy23
Studying metabolism with multi-organ chips: new tools for disease modelling, pharmacokinetics and pharmacodynamics22
C-terminal glycosylation of type IX secretion system cargo proteins in Prevotella intermedia with both short and long secretion signals22
The genetic basis and potential molecular mechanism of yellow-albino northern snakehead (Channa argus)22
Freshwater-adapted polychaetes exhibit a complete enzymatic machinery for synthesizing long-chain polyunsaturated fatty acids22
Long-read RNA-sequencing reveals transcript-specific regulation in human-derived cortical neurons20
Interplay between circadian rhythm, ageing and neurodegenerative disorder20
miR-155-3p: processing by-product or rising star in immunity and cancer?20
Light-induced reversible reorganizations in closed Type II reaction centre complexes: physiological roles and physical mechanisms19
The budding yeast GSK-3 homologue Mck1 is an essential component of the spindle position checkpoint19
Multifunctional roles of Sec13 paralogues in the euglenozoan Trypanosoma brucei19
Proteomic comparison of the organic matrices from parietal and base plates of the acorn barnacle Amphibalanus amphitrite18
Genome-wide identification of ATP-binding cassette transporter B subfamily, focusing on its structure, evolution and rearrangement in ciliates18
Interactions of N- and C-terminal parts of Ana1 permitting centriole duplication but not elongation18
A circle of life: platelet and megakaryocyte cytoskeleton dynamics in health and disease18
Learning-induced remodelling of inhibitory synapses in the motor cortex18
Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria17
Stepwise order in protein complex assembly: approaches and emerging themes17
The supernumerary B chromosome of maize: drive and genomic conflict16
Polycomb-mediated transgenerational epigenetic inheritance of Drosophila eye colour is independent of small RNAs16
Transcriptional regulation as a dose-dependent process: insights from transcription factor tuning16
Reversible bacteriophage resistance by shedding the bacterial cell wall16
Expression of concern: ‘RNA editing of microRNA prevents RNA-induced silencing complex recognition of target mRNA’ (2015), by Cui Y et al.16
Neuronal signalling of zinc: from detection and modulation to function16
GNL3 is an evolutionarily conserved stem cell gene influencing cell proliferation, animal growth and regeneration in the hydrozoan Hydractinia15
Plant NLR immunity activation and execution: a biochemical perspective15
Whole organism and tissue-specific analysis of pexophagy in Drosophila15
Aurodox inhibits type III secretion in multiple Gram-negative pathogens15
Temperature activated transient receptor potential ion channels from Antarctic fishes15
The lipid linked oligosaccharide polymerase Wzy and its regulating co-polymerase, Wzz, from enterobacterial common antigen biosynthesis form a complex15
A distinct phase of cyclin B (Cdc13) nuclear export at mitotic entry in Schizosaccharomyces pombe14
Effective training of nanopore callers for epigenetic marks with limited labelled data14
Identification of the modulatory Ca 2+ -binding sites of acid-sensing ion channel 1a14
GLP-1/GLP-1R axis: from metabolism (obesity and T2DM) to immunity14
Regulation of EGFR signalling by palmitoylation and its role in tumorigenesis14
Terminal regions of a protein are a hotspot for low complexity regions and selection14
Spatial transcriptomes and microbiota reveal immune mechanism that respond to pathogen infection in the posterior intestine ofSebastes schlegelii14
Retraction: ‘MALAT1 promotes gastric adenocarcinoma through the MALAT1/miR-181a-5p/AKT3 axis’ (2019), by Lu et al.14
MicroRNAs: master regulators in host–parasitic protist interactions14
Mitochondrial chaperonin DNAJC15 promotes vulnerability to ferroptosis of chemoresistant ovarian cancer cells14
Unravelling axonal transcriptional landscapes: insights from induced pluripotent stem cell-derived cortical neurons and implications for motor neuron degeneration13
Exploring the midgut physiology of the non-haematophagous mosquito Toxorhynchites theobaldi13
PACS deficiency disrupts Golgi architecture and causes cytokinesis failures and seizure-like phenotype in Drosophila melanogaster13
Emerging evidence implicating a role for neurexins in neurodegenerative and neuropsychiatric disorders13
Decoding frontotemporal and cell-type-specific vulnerabilities to neuropsychiatric disorders and psychoactive drugs13
Pseudogenization of NK3 homeobox 2 ( Nkx3.2 ) in monotremes provides insight into unique gastric anatomy and physiology13
PIEZO1 variant implications for biological understanding and human health13
Retraction: ‘Long non-coding RNA LINC00467 regulates hepatocellular carcinoma progression by modulating miR-9-5p/PPARA expression’ (2019), by Cai et al.13
Insights into the bioluminescence systems of three sea pens (Cnidaria: Anthozoa): from de novo transcriptome analyses to biochemical assays12
Novel in vivo TDP-43 stress reporter models to accelerate drug development in ALS12
Mapping combinatorial expression of non-clustered protocadherins in the developing brain identifies novel PCDH19-mediated cell adhesion properties12
Spatial positioning of preimplantation mouse embryo cells is regulated by mTORC1 and m 7 G-cap-dependent translation at the 8- to 16-cell transition12
The challenge of measuring mosquito flight performance: going beyond sterile insect technique and into transgenic and gene drive-based approaches12
Polo-like kinase and Aurora B kinase phosphorylate and cooperate with the CIF1-CIF2 complex to promote cytokinesis initiation in Trypanosoma brucei12
Exploring differential exon usage via short- and long-read RNA sequencing strategies12
Centromere function in asymmetric cell division in Drosophila female and male germline stem cells12
Daughter centrioles assemble preferentially towards the nuclear envelope in Drosophila syncytial embryos12
A simple inland culture system provides insights into ascidian post-embryonic developmental physiology12
Structural insights into a regulatory mechanism of FIR RRM1–FUSE interaction12
Capturing crop adaptation to abiotic stress using image-based technologies11
Discovery of unique mitotic mechanisms in Paradiplonema papillatum11
Lysosomal positioning diseases: beyond substrate storage11
Aspirin and cancer: biological mechanisms and clinical outcomes11
Hypoxia impedes differentiation of cranial neural crest cells into derivatives relevant for craniofacial development11
Pigment-dispersing factor neuropeptides act as multifunctional hormones and modulators in tardigrades11
Expression and function of PDGF-C in development and stem cells11
TRIM family proteins: roles in proteostasis and neurodegenerative diseases11
The proline-rich antimicrobial peptide B7-005: low bacterial resistance, safe for human cells and effective in zebrafish embryo bacteraemia model10
Distinct molecular profile of the chick organizer as a stem zone during axial elongation10
2024: The quest continues10
Phosphorylation of ‘SDT-like’ motifs in ATRX mediates its interaction with the MRN complex and is important for ALT pathway suppression10
Correlative super-resolution analysis of cardiac calcium sparks and their molecular origins in health and disease10
Plum modulates Myoglianin and regulates synaptic function in D. melanogaster10
Neuroanatomical characterization of the Nmu-Cre knock-in mice reveals an interconnected network of unique neuropeptidergic cells10
Proposed three-phenylalanine motif involved in magnetoreception signalling of an Actinopterygii protein expressed in mammalian cells10
The post-translational modification O-GlcNAc is a sensor and regulator of metabolism9
Elevated basal AMP-activated protein kinase activity sensitizes colorectal cancer cells to growth inhibition by metformin9
Examination of gammarid transcriptomes reveals a widespread occurrence of key metabolic genes from epibiont bdelloid rotifers in freshwater species9
Cooperative motility, force generation and mechanosensing in a foraging non-photosynthetic diatom9
The C-terminus of CFAP410 forms a tetrameric helical bundle that is essential for its localization to the basal body9
Time-optimized feeding is beneficial without enforced fasting9
Single-cell expression predicts neuron-specific protein homeostasis networks9
Modern and prebiotic amino acids support distinct structural profiles in proteins9
Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH9
Evolution and assembly of Anopheles aquasalis 's immune genes: primary malaria vector of coastal Central and South America and the Caribbean Islands9
Pigment-dispersing factor is present in circadian clock neurons of pea aphids and may mediate photoperiodic signalling to insulin-producing cells9
Prebiotic chemistry: a review of nucleoside phosphorylation and polymerization9
Mapping molecular complexes with super-resolution microscopy and single-particle analysis8
The gender-specific impact of starvation on mitotypes diversity in adults of Drosophila melanogaster8
Retraction: ‘TNF-α-induced NF-κB activation upregulates microRNA-150-3p and inhibits osteogenesis of mesenchymal stem cells by targeting β-catenin’ (2016), by Wang et al.8
Cancer cells’ chamber of secrets: the link between micronuclei, chromothripsis and malignancy8
ARNO is recruited by the neuronal adaptor FE65 to potentiate ARF6-mediated neurite outgrowth8
Expression of concern: ‘TNF-α-induced NF-κB activation upregulates microRNA-150-3p and inhibits osteogenesis of mesenchymal stem cells by targeting β-catenin’ (2016), by Wang N et al.8
Exaggerated trans-membrane charge of ammonium transporters in nutrient-poor marine environments8
miR-1202 acts as anti-oncomiR in myeloid leukaemia by down-modulating GATA-1 S expression8
Identification of a small RhoA GTPase inhibitor effective in fission yeast and human cells8
High-throughput functional analysis provides novel insight into type VII secretion in Staphylococcus aureus8
Repo-Man/protein phosphatase 1 SUMOylation mediates binding to lamin A and serine 22 dephosphorylation8
Phylogenomic diversity of archigregarine apicomplexans8
Modulating streptococcal phenotypes using signal peptide analogues8
Mechanotransduction as a major driver of cell behaviour: mechanisms, and relevance to cell organization and future research8
A diversified and segregated mRNA spliced-leader system in the parasitic Perkinsozoa8
Efficient CRISPR/Cas9-mediated gene disruption in the tetraploid protist Giardia intestinalis8
Systemic analyses show that the biosynthesis and spatial distribution of fatty acids, triglycerides and lipids differed in male and female mice and humans8
Analysis of the phosphoproteome of CK2 α (–/–)α′ C2C12 myoblasts compared to the wild-type cells8
Retraction: ‘Involvement of miR-4262 in paclitaxel resistance through the regulation of PTEN in non-small cell lung cancer’ (2019), by Sun et al.8
Multiple factors contribute to female dominance in migratory bioflows8
Notch and LIM-homeodomain protein Arrowhead regulate each other in a feedback mechanism to play a role in wing and neuronal development in Drosophila8
O-GlcNAcylation of the intellectual disability protein DDX3X exerts proteostatic cell cycle control8
Expression of concern: DDP-resistant ovarian cancer cells-derived exosomal microRNA-30a-5p reduces the resistance of ovarian cancer cells to DDP8
Myeloid-derived suppressor cells and the pathogenesis of human immunodeficiency virus infection8
Biochemistry and physiology of voltage-gated calcium channel trafficking: a target for gabapentinoid drugs8
Characterization and functional analysis of zinc trafficking in the human fungal pathogen Candida parapsilosis8
Quantifying the large-scale chromosome structural dynamics during the mitosis-to-G1 phase transition of cell cycle8
Short chain fatty acids: key regulators of the local and systemic immune response in inflammatory diseases and infections8
Intense light unleashes male–male courtship behaviour in wild-type Drosophila7
Expression of concern: ‘Long non-coding RNA LINC00346 contributes to cisplatin resistance in nasopharyngeal carcinoma by repressing miR-342-5p’ (2020), by Cui Z et al.7
The role of endothelial-derived factors in neural tube development: implications for organoid models7
Characterization of microglia behaviour in healthy and pathological conditions with image analysis tools7
Simple, streamlined, cost-effective cDNA synthesis method from cell cultures7
The potential roles of retinoids in combating drug resistance in cancer: implications of ATP-binding cassette (ABC) transporters7
An MD-2-related lipid-recognition protein is required for insect reproduction and integument development7
Improvement of the antibody-dependent respiratory burst assay for assessing protective immune responses to malaria7
Quantitative single molecule analysis of podoplanin clustering in fibroblastic reticular cells uncovers CD44 function7
Axon demyelination and degeneration in a zebrafish spastizin model of hereditary spastic paraplegia7
The cytosolic form of dual localized BolA family protein Bol3 is important for adaptation to iron starvation in Aspergillus fumigatus7
A critical threshold of MCM10 is required to maintain genome stability during differentiation of induced pluripotent stem cells into natural killer cells7
Reinventing the spermatheca: unveiling a novel sperm storage organ in Epilachninae ladybirds7
Mitochondrial-derived gene expression in hibernation: tissue-specific responses in the thirteen-lined ground squirrel6
The immune deficiency and c-Jun N-terminal kinase pathways drive the functional integration of the immune and circulatory systems of mosquitoes6
Pattern recognition in living cells through the lens of machine learning6
Functional disruption of oxytocin projections participates atypical social and anxiety-like behaviours in BTBR mouse model of autism6
Single-molecule tracking (SMT) and localization of SRF and MRTF transcription factors during neuronal stimulation and differentiation6
Selective loss of ATP carriers in favour of SLC25A43 orthologues in metamonad mitochondria adapted to anaerobiosis6
In vivoassessment of mechanical properties during axolotl development and regeneration using confocal Brillouin microscopy6
IFNγ-dependent silencing of TFF1 during Helicobacter pylori infection6
A novel FAM83G variant from palmoplantar keratoderma patient disrupts WNT signalling via loss of FAM83G-CK1α interaction6
The fission yeast NDR kinase Orb6 and its signalling pathway MOR regulate cytoplasmic microtubule organization during the cell cycle6
Unveiling the functional nature of retrogenes in dinoflagellates6
High-resolution analysis of individual Drosophila melanogaster larvae uncovers individual variability in locomotion and its neurogenetic modulation6
Proximal partners of the organellar N-terminal acetyltransferase NAA60: insights into Golgi structure and transmembrane protein topology6
The CoREST complex regulates multiple histone modifications temporal-specifically in clock neurons6
The nature of ‘jaws’: a new predatory representative of Provora and the ultrastructure of nibbling protists6
The human HELQ helicase and XRN2 exoribonuclease cooperate in R-loop resolution6
Plasmodium LCCL domain-containing modular proteins have their origins in the ancestral alveolate6
Plasmodium berghei leucine-rich repeat protein 1 downregulates protein phosphatase 1 activity and is required for efficient oocyst development6
Multi-epitope vaccine candidates based on mycobacterial membrane protein large (MmpL) proteins against Mycobacterium ulcerans6
Gene duplication is the primary driver of intraspecific genomic divergence in coral algal symbionts6
The histone deacetylase inhibitor Scriptaid targets G-quadruplexes6
Regional random mutagenesis driven by multiple sgRNAs and diverse on-target genome editing events to identify functionally important elements in non-coding regions6
Correction to: ‘The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence’ (2016), by Burla et al.6
Evaluating the efficacy of protein quantification methods on membrane proteins6
Patterning principles of morphogen gradients6
Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates in primary neurons6
Haploidy-linked cell proliferation defects limit larval growth in zebrafish6
Structure and molecular basis of spermatid elongation in theDrosophilatestis6
Restricting a single amino acid cross-protects Drosophila melanogaster from nicotine poisoning through mTORC1 and GCN2 signalling5
The cuticular wax composition and crystal coverage of leaves and petals differ in a consistent manner between plant species5
Live imaging YAP signalling in mouse embryo development5
Recent advances in understanding of enterobacterial common antigen synthesis and regulation5
ELMOD3-Rab1A-Flotillin2 cascade regulates lumen formation via vesicle trafficking inCionanotochord5
A high-throughput protein tagging toolkit that retains endogenous untranslated regions for studying gene regulation in kinetoplastids5
POU-M2 promotes juvenile hormone biosynthesis by directly activating the transcription of juvenile hormone synthetic enzyme genes in Bombyx mori5
Implications of canonical histone H3.1 and histone variant H3.3 in cancer5
Mechanisms driving spatial distribution of residents in colony biofilms: an interdisciplinary perspective5
The information overload, immunology and their relationship to world health5
Prenatal transcript levels and metabolomics analyses reveal metabolic changes associated with intrauterine growth restriction and sex5
Brain amino acid sensing for organismal amino acid homeostasis5
Bacterial division ring stabilizing ZapA versus destabilizing SlmA modulate FtsZ switching between biomolecular condensates and polymers5
tRNA copy number and codon usage in the sea cucumber genome provide insights into adaptive translation for saponin biosynthesis5
Cell cycle visualization tools to study cardiomyocyte proliferation in real-time5
Insulin receptor Arg717 and IGF-1 receptor Arg704 play a key role in ligand binding and in receptor activation5
Evolutionary mode for the functional preservation of fast-evolving Drosophila telomere capping proteins5
AMPK phosphorylates NAMPT to regulate NAD + homeostasis under ionizing radiation5
MYC regulates metabolism through vesicular transfer of glycolytic kinases5
Gut microbiota diversity affects fish behaviour and is influenced by host genetics and early rearing conditions5
Microsporidian parasite impairs colony fitness in bumblebees5
Molecular and morphological approach to study the innexin gap junctions in Rhynchosciara americana5
Correction to ‘Global pleiotropic effects in adaptively evolved Escherichia coli lacking CRP reveal molecular mechanisms that define the growth physiology’5
Greatwall-Endos-PP2A/B55 Twins network regulates translation and stability of maternal transcripts in the Drosophila oocyte-to-embryo 5
NFIL3 contributes to cytotoxic T lymphocyte-mediated killing5
Polo-like kinase 1 promotes Cdc42-induced actin polymerization for asymmetric division in oocytes5
Ultrastructure expansion microscopy in Trypanosoma brucei5
Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-25
Mutant SPART causes defects in mitochondrial protein import and bioenergetics reversed by Coenzyme Q5
Ovothiol ensures the correct developmental programme of the sea urchin Paracentrotus lividus embryo5
Sperm-borne mRNAs: potential roles in zygote genome activation and epigenetic inheritance5
ATP-dependent polymerization dynamics of bacterial actin proteins involved in Spiroplasma swimming5
Mitochondrial biology and dysfunction in secondary mitochondrial disease5
PK1 from Drosophila obscurin is an inactive pseudokinase with scaffolding properties5
Cell autonomous and non-autonomous consequences of deviations in translation machinery on organism growth and the connecting signalling pathways5
A transgenic zebrafish forin vivovisualization of cilia5
Elongation capacity of polyunsaturated fatty acids in the annelid Platynereis dumerilii4
DNA fragility at the KMT2A / MLL locus: insights from old and new technologies4
Skewed distribution of spines is independent of presynaptic transmitter release and synaptic plasticity, and emerges early during adult neurogenesis4
Correction to: ‘The functional diversity of the POUV-class proteins across vertebrates’ (2022) by Bakhmet and Tomilin4
Genomic, transcriptomic and epigenomic signatures of ageing and cold adaptation in the Antarctic clam Laternula elliptica4
Single amino acid substitutions in hydrophobic cores at a head-coiled coil junction region of cohesin facilitate its release of DNA during anaphase4
Lipopolysaccharide detection by the innate immune system may be an uncommon defence strategy used in nature4
HSD3B1 is an oxysterol 3β-hydroxysteroid dehydrogenase in human placenta4
Krüppel-homologue 1regulates the development ofTuta absolutaand its cascade regulation pattern in the juvenile hormone signalling pathway4
Identification of PP2A-B55 targets uncovers regulation of emerin during nuclear envelope reassembly inDrosophila4
Opium alkaloids, biosynthesis, pharmacology and association with cancer occurrence4
The functional diversity of the POUV-class proteins across vertebrates4
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