Bone & Joint Research

Article	Citations
Mental health implications of fracture-related infections	89
Intra-articular celecoxib improves knee extension regardless of surgical release in a rabbit model of arthrofibrosis	61
Mechanical influence of facet tropism in patients with chronic discogenic pain disorder	60
Comparison of periprosthetic femoral fracture torque and strain pattern of three types of femoral components in experimental model	53
Systemic glucose-insulin-potassium reduces skeletal muscle injury, kidney injury, and pain in a murine ischaemia-reperfusion model	47
Osteoporosis: current screening methods, novel techniques, and preoperative assessment of bone mineral density	47
The effect of ethnicity on the age-related changes of spinopelvic characteristics: a systematic review	46
Prognostic factors associated with failure of total elbow arthroplasty	41
Can severity of trunnion damage be estimated by visual inspection alone?	39
Defining the optimal position of the lipped liner in combination with cup orientation and stem version	38
The metabolic equivalent of task score	36
Exosomes from dysfunctional chondrocytes affect osteoarthritis in Sprague-Dawley rats through FTO-dependent regulation of PIK3R5 mRNA stability	33
Effect of the additional anteroposterior blocking screw on nail/medullary canal mismatch after cephalomedullary nailing in unstable pertrochanteric fracture	32
Diagnosing periprosthetic joint infections	31
Bi-unicondylar arthroplasty	29
Cartilage oligomeric matrix protein as a potential biomarker for knee osteoarthritis	29
Classification of distinct osteoarthritis subtypes with different knee joint tissues by gene expression profiles	29
Molecular crosstalk between articular cartilage, meniscus, synovium, and subchondral bone in osteoarthritis	28
Prediction of implant failure risk due to periprosthetic femoral fracture after primary elective total hip arthroplasty	27
Finite element analysis safety of tibial cortex transverse transport	27
Osteochondral lesions of talus	27
The CREB1 inhibitor 666-15 maintains cartilage homeostasis and mitigates osteoarthritis progression	26
Sheep condyle model evaluation of bone marrow cell concentrate combined with a scaffold for repair of large osteochondral defects	25
Preoperative measures of bone mineral density from digital wrist radiographs	24
The role of cells and signal pathways in subchondral bone in osteoarthritis	23

Orientin alleviates chondrocyte senescence and osteoarthritis by inhibiting PI3K/AKT pathway	23
Comprehensive analysis of pathological changes in hip joint capsule of patients with developmental dysplasia of the hip	23
Application of loaded graphene oxide biomaterials in the repair and treatment of bone defects	22
Don’t mind the gap: reframing the Perren strain rule for fracture healing using insights from virtual mechanical testing	22
Beyond the surface: anterior cruciate ligament assessment in knee osteoarthritis	21
Cyclooxygenase-2 negatively regulates osteogenic differentiation in murine bone marrow mesenchymal stem cells via the FOXO3a/p27kip1 pathway	21
Hederagenin promotes SIRT6 to attenuate epidural scar formation by aggravating PRMT1 deacetylation	20
A comparison of clinical and radiological outcomes between two different biodegradable local antibiotic carriers used in the single-stage surgical management of long bone osteomyelitis	19
Future registry research	19
Accumulation of advanced oxidation protein products contributes to age-related impairment of gap junction intercellular communication in osteocytes of male mice	19
CXCR4 is a response gene for parathyroid hormone which affects osteoblast and osteoclast function in vitro	19
Histone deacetylase inhibitors attenuated interleukin-1β-induced chondrogenesis inhibition in synovium-derived mesenchymal stem cells of the temporomandibular joint	19
Human acellular amniotic membrane scaffolds encapsulating juvenile cartilage fragments accelerate the repair of rabbit osteochondral defects	18
Detection of rare microorganisms in bone and joint infections by metagenomic next-generation sequencing	18
Transcriptome-wide association study identifies new susceptibility genes for degenerative cervical spondylosis	18
Tibial cortex transverse transport accelerates wound healing via enhanced angiogenesis and immunomodulation	17
Detection limitations of bacteria in tissue samples	17
Decreased Peli1 expression attenuates osteoarthritis by protecting chondrocytes and inhibiting M1-polarization of macrophages	17
siRNA incorporated in slow-release injectable hydrogel continuously silences DDIT4 and regulates nucleus pulposus cell pyroptosis through the ROS/TXNIP/NLRP3 axis to alleviate intervertebral disc dege	16
Proximal humerus fractures – epidemiology, comparison of mortality rates after surgical versus non-surgical treatment, and analysis of risk factors based on Medicare registry data	16
Ultrasound-targeted simvastatin-loaded microbubble destruction promotes OA cartilage repair by modulating the cholesterol efflux pathway mediated by PPARγ in rabbits	16
Do preoperative intra-articular injections of corticosteroids or hyaluronic acid increase the risk of infection after total knee arthroplasty? A meta-analysis	15
Diathermy and bone sawing are high aerosol yield procedures	15
Current therapeutic interventions combating biofilm-related infections in orthopaedics	15
A large-scale genetic correlation scan between rheumatoid arthritis and human plasma protein	15
Induction heating combined with antibiotics or SAAP-148 effectively reduces biofilm-embedded Staphylococcus aureus on a fracture-related implant mimic	15
Modelling osteoarthritis in mice via surgical destabilization of the medial meniscus with or without a stereomicroscope	15
Identification of age-related genes in rotator cuff tendon	15
Panoramic heat map for spatial distribution of necrotic lesions	14
Development and validation of a modularized external fixator for generating standardized fracture healing micromotions in rats	14
HDACi vorinostat protects muscle from degeneration after acute rotator cuff injury in mice	14
Preoperative prediction for periprosthetic bone loss and individual evaluation of bisphosphonate effect after total hip arthroplasty using artificial intelligence	14
Reviewer acknowledgement	14
The role of AGEs in pathogenesis of cartilage destruction in osteoarthritis	13
Infographic: Osteoimmunology mechanism of osteonecrosis of the femoral head	13
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary hip arthroplasty in England and Wales	13
Capsular ligaments provide a passive stabilizing force to protect the hip against edge loading	13
The complexity of decision-making for total hip arthroplasty in early osteoarthritis	12
Correlation of cross-linking as measured by the trans-vinylene index and in vitro wear of polyethylene from various acetabular liner brands	12
Incidence and risk factors of recurrence in limb osteomyelitis patients after antibiotic‐loaded cement spacer for definitive bone defect treatment	12
The role of AGEs in muscle ageing and sarcopenia	12
Anterior cruciate ligament remnant preservation attenuates apoptosis and enhances the regeneration of hamstring tendon graft	12
The effect of cement augmentation on pedicle screw fixation under various load cases	12
Corrigendum	12
Urgent focus on enhanced recovery after surgery of AIDS patients with limb fractures	12
Impact of tranexamic acid on the efficacy of vancomycin and meropenem against periprosthetic joint infections	12
The prevalence and treatment of osteoporosis in patients undergoing total hip arthroplasty and the levels of biochemical markers of bone turnover	12
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary knee arthroplasty in England and Wales	11
Hsa_circ_0066523 promotes the proliferation and osteogenic differentiation of bone mesenchymal stem cells by repressing PTEN	11
Impact of elevated sclerostin levels on bone resorption	11

Overcoming floor and ceiling effects in knee arthroplasty outcome measurement	11
Defining the extracellular matrix in non-cartilage soft-tissues in osteoarthritis: a systematic review	11
The reconstruction of critical bone loss	10
Femoral impingement in maximal hip flexion is anterior-inferior distal to the cam deformity in femoroacetabular impingement patients with femoral retroversion	10
Developmental endothelial locus-1 attenuates palmitate-induced apoptosis in tenocytes through the AMPK/autophagy-mediated suppression of inflammation and endoplasmic reticulum stress	10
Osteocyte-specific dentin matrix protein 1	10
Efficacy of EDTA-NS irrigation in eradicating Staphylococcus aureus biofilm-associated infection	10
Prioritization versus rationing of healthcare – elective surgery is not optional surgery	10
Factors associated with Achilles tendon re-rupture following operative fixation	10
Single-cell transcriptomics analysis of the healing process of ligament rupture	10
Basic research for ultrasound-guided injection into skeletal muscle lesions in an experimental animal model	10
Mucin 1 aggravates synovitis and joint damage of rheumatoid arthritis by regulating inflammation and aggression of fibroblast-like synoviocytes	10
Human osteoblasts obtained from distinct periarticular sites demonstrate differences in biological function in vitro	10
Extended local release and improved bacterial eradication by adding rifampicin to a biphasic ceramic carrier containing gentamicin or vancomycin	9
Exercise modifies the disease-relevant gut microbial shifts in post-traumatic osteoarthritis rats	9
Long-term hypoxic atmosphere enhances the stemness, immunoregulatory functions, and therapeutic application of human umbilical cord mesenchymal stem cells	9
Evaluating upper leg muscle volume	9
Adenosine, lidocaine, and magnesium therapy augments joint tissue healing following experimental anterior cruciate ligament rupture and reconstruction	9
Beta-caryophyllene prevents the defects in trabecular bone caused by Vitamin D deficiency through pathways instated by increased expression of klotho	9
Increased local bone turnover in patients with chronic periprosthetic joint infection	9
Rifampicin restores extracellular organic matrix formation and mineralization of osteoblasts after intracellular Staphylococcus aureus infection	9
Augmentation of implant surfaces with BMP-2 in a revision setting	9
Effect of resistance training on satellite cells in old mice – a transcriptome study	9
Evaluation of the causal relationship between 28 circulating biomarkers and osteoarthritis	9
The role of Staphylococcus aureus small colony variants in intraosseous invasion and colonization in periprosthetic joint infection	9
Overcoming the detrimental impact of volumetric muscle loss on segmental fracture healing via the induced membrane technique	8
Effectiveness of mechanical cleaning, antibiotics, and induction heating on eradication of Staphylococcus aureus in mature biofilms	8
Increased loading of the lateral knee compartment in the unamputated knee during gait in people with unilateral transfemoral/through-knee amputations	8
PEDF peptide plus hyaluronic acid stimulates cartilage regeneration in osteoarthritis via STAT3-mediated chondrogenesis	8
Clinical, oncological, and prognostic differences of patients with subsequent skeletal-related events in bone metastases	8
Suramin attenuates intervertebral disc degeneration by inhibiting NF-κB signalling pathway	8
Importance of posterior tibial slope in joint kinematics with an anterior cruciate ligament-deficient knee	8
The impact of cementing technique in polished taper fit hip stems	8
Effects of high antibiotic concentrations applied to continuous local antibiotic perfusion on human bone tissue-derived cells	8
Development and validation of a novel prediction model for osteoporosis	8
Identification of the molecular link: STAT3 is a shared key gene linking postmenopausal osteoporosis and sarcopenia	8
Qualitative methods: the missing link in orthopaedic research	8
The degenerated glenohumeral joint	8
TGF-β1 derived from macrophages contributes to load-induced tendon-bone healing in the murine rotator cuff repair model by promoting chondrogenesis	8
Immunomodulatory role of T helper cells in rheumatoid arthritis	8
Growth differentiation factor 15 as a potential diagnostic biomarker for rheumatoid arthritis	7
Integrating genome-wide association study with regulatory SNP annotations identified novel candidate genes for osteoporosis	7
Osteoblast function in patients with idiopathic osteonecrosis of the femoral head	7
Alcohol-induced inhibition of bone formation and neovascularization contributes to the failure of fracture healing via the miR-19a-3p/FOXF2 axis	7
What is the appropriate extended duration of antibiotic prophylaxis after two-stage revision for chronic PJI?	7
Infographic: Three key elements of kinematic alignment total knee arthroplasty for clarified understanding of its approaches	7
Intra-articular versus systemic vancomycin for the treatment of periprosthetic joint infection after debridement and spacer implantation in a rat model	7
Reviewer acknowledgement	7
Reviewer acknowledgement	7
Astragalus polysaccharide promotes osteogenic differentiation of human bone marrow derived mesenchymal stem cells by facilitating ANKFY1 expression through miR-760 inhibition	7
Infographic: Chongqing technique	7
Intermittent parathyroid hormone increases stability and improves osseointegration of initially unstable implants	7
Efficacy of a saline wash plus vancomycin/tobramycin-doped PVA composite (PVA-VAN/TOB-P) in a mouse pouch infection model implanted with 3D-printed porous titanium cylinders	7
Dihydrocaffeic acid improves IL-1β-induced inflammation and cartilage degradation via inhibiting NF-κB and MAPK signalling pathways	7
The interactions of macrophages, lymphocytes, and mesenchymal stem cells during bone regeneration	7
The primary stability of the femoral component in cemented single and twin peg Oxford unicompartmental knee arthroplasty under adverse conditions	7
Volume and location of bone regeneration after autologous expanded mesenchymal stromal cells in hip osteonecrosis	6
The accuracy of restoration of femoral head centre of rotation in the anteroposterior plane after uncemented total hip arthroplasty	6
Stable polyethylene inlay fixation and low polyethylene wear rate in fixed-bearing total knee arthroplasty at five to six years’ follow-up	6
Retraction notice	6
Melatonin protects human nucleus pulposus cells from pyroptosis by regulating Nrf2 via melatonin membrane receptors	6
3D printing in orthopaedic surgery: a scoping review of randomized controlled trials	6
Changes in the shape of the lumbar curve during growth	6
Are we doing the right surgical trials?	6
Damage control orthopaedics is associated with impaired fracture healing and delayed recovery in a rodent model of severe multiple trauma	6
LncRNA PCBP1-AS1 induces osteoporosis by sponging miR-126-5p/PAK2 axis	6
A bilayer scaffold of collagen and nanohydroxyapatite promotes osteochondral defect repair in rabbit knee joints	6
The IMPACT of COVID-19 on trauma & orthopaedic surgery provides lessons for future communicable disease outbreaks	6
Identification of mechanics-responsive osteocyte signature in osteoarthritis subchondral bone	6
Terminology of bone and joint infection	6
Meniscus cell lysate induces mitochondrial dysfunction of fibroblast-like synoviocytes via upregulating ANT3 in osteoarthritis	6
Robotic-arm assisted THA can achieve precise cup positioning in developmental dysplasia of the hip	6
Infographic: Total hip arthroplasty in early osteoarthritis	6
Repetitive combined doses of bacteriophages and gentamicin protect against Staphylococcus aureus implant-related infections in Galleria mellonella	6
Regeneration of injured articular cartilage using the recombinant human amelogenin protein	6
Cytokines and regulatory T cells in ankylosing spondylitis	6
Concomitant osteochondral lesion of the talus affects in vivo ankle kinetics in patients with chronic ankle instability	5
In vivo reduction of biofilm seeded on orthopaedic implants	5
Enhancement of hyaline cartilage and subchondral bone regeneration in a rat osteochondral defect model through focused extracorporeal shockwave therapy	5
Melatonin induces RAW264.7 cell apoptosis via the BMAL1/ROS/MAPK-p38 pathway to improve postmenopausal osteoporosis	5

The role of EDIL3 in maintaining cartilage extracellular matrix and inhibiting osteoarthritis development	5
Development and validation of an open-source tool for opportunistic screening of osteoporosis from hip CT images	5
Bone turnover markers as surrogates of fracture healing after intramedullary fixation of tibia and femur fractures	5
Meaningful values in the Short Form Health Survey-36 after total knee arthroplasty – an alternative to the EuroQol five-dimension index as a measure for health-related quality of life	5
Aberrant anabolism hinders constructive metabolism of chondrocytes by pharmacotherapy in osteoarthritis	5
Intra-articular low-dose parathyroid hormone (1-34) improves mobility and articular cartilage quality in a preclinical age-related knee osteoarthritis model	5
Platelets mediate trained immunity against bone and joint infections in a mouse model	5
Erratum	5
Monomeric CRP regulates inflammatory responses in human intervertebral disc cells	5
Clinical efficacy and safety of P-15 peptide enhanced bone graft substitute in surgical bone regenerative procedures in adult maxillofacial, spine, and trauma patients	5
Effect of treadmill training on fibrocartilage complex repair in tendon-bone insertion healing in the postinflammatory stage	5
Wound fluid ceftriaxone concentrations after local application with calcium sulphate as carrier material in the treatment of orthopaedic device-associated hip infections	5
Rapid multiplex micro-ELISA assay for simultaneous measurement of synovial biomarkers	5
Outcomes following surgical management of femoroacetabular impingement: a systematic review and meta-analysis of different surgical techniques	5
Appraising causal risk and protective factors for rheumatoid arthritis	5
Clinical outcomes following intra-articular injection of autologous adipose-derived mesenchymal stem cells for the treatment of osteoarthritis in dogs characterized by weight-bearing asymmetry	5
The role of BioFire Joint Infection Panel in diagnosing periprosthetic hip and knee joint infections in patients with unclear conventional microbiological results	5
The Clinical Practice Integration of Artificial Intelligence (CPI-AI) framework	5
Tendon healing: a concise review on cellular and molecular mechanisms with a particular focus on the Achilles tendon	5
Knee kinematics during staircase descent	5
BRD4promotes heterotopic ossification through upregulation of LncRNA MANCR	5
Upregulated ribosome pathway plays a key role in HDAC4, improving the survival rate and biofunction of chondrocytes	5
Cyclin D1 mediates pain behaviour in a rat model of breast cancer-induced bone pain by a mechanism involving regulation of the proliferation of spinal microglia	5
Repurposing the diuretic benzamil as an anti-osteosarcoma agent that acts by suppressing integrin/FAK/STAT3 signalling and compromising mitochondrial function	5
Multiple roles of ALK3 in osteoarthritis	5
Predicted waiting times for orthopaedic surgery	5
Effect of secretory leucocyte protease inhibitor on early tendon-to-bone healing after anterior cruciate ligament reconstruction in a rat model	5