Bone & Joint Research

Article	Citations
Mental health implications of fracture-related infections	151
The future of osteoarthritis treatment: exploring the potential of exosomes from adipose tissue-derived stem cells	91
Comparison of periprosthetic femoral fracture torque and strain pattern of three types of femoral components in experimental model	86
Prognostic factors associated with failure of total elbow arthroplasty	83
The effect of ethnicity on the age-related changes of spinopelvic characteristics: a systematic review	79
Mechanical influence of facet tropism in patients with chronic discogenic pain disorder	72
Candy box technique with sutures and Nice knot	52
Systemic glucose-insulin-potassium reduces skeletal muscle injury, kidney injury, and pain in a murine ischaemia-reperfusion model	46
Can severity of trunnion damage be estimated by visual inspection alone?	45
Feasibility and reliability of shear wave elastography-guided collateral ligament balancing during total knee arthroplasty	42
Cartilage oligomeric matrix protein as a potential biomarker for knee osteoarthritis	37
Diagnosing periprosthetic joint infections	32
Exosomes from dysfunctional chondrocytes affect osteoarthritis in Sprague-Dawley rats through FTO-dependent regulation of PIK3R5 mRNA stability	31
The metabolic equivalent of task score	31
Classification of distinct osteoarthritis subtypes with different knee joint tissues by gene expression profiles	30
Defining the optimal position of the lipped liner in combination with cup orientation and stem version	30
Therapeutic potential of IκB kinase epsilon inhibition in preventing meniscal degeneration of early osteoarthritis	29
Osteochondral lesions of talus	28
The role of cells and signal pathways in subchondral bone in osteoarthritis	28
Molecular crosstalk between articular cartilage, meniscus, synovium, and subchondral bone in osteoarthritis	28
Orientin alleviates chondrocyte senescence and osteoarthritis by inhibiting PI3K/AKT pathway	27
Discogenic pain in lumbar vertebra	26
Reviewer acknowledgement	25
Application of loaded graphene oxide biomaterials in the repair and treatment of bone defects	24
Finite element analysis safety of tibial cortex transverse transport	24

The CREB1 inhibitor 666-15 maintains cartilage homeostasis and mitigates osteoarthritis progression	23
Paclitaxel-mediated microtubule stabilization regulates flexor tendon repair in rats	22
Beyond the surface: anterior cruciate ligament assessment in knee osteoarthritis	22
Cyclooxygenase-2 negatively regulates osteogenic differentiation in murine bone marrow mesenchymal stem cells via the FOXO3a/p27kip1 pathway	22
Prediction of implant failure risk due to periprosthetic femoral fracture after primary elective total hip arthroplasty	22
Human acellular amniotic membrane scaffolds encapsulating juvenile cartilage fragments accelerate the repair of rabbit osteochondral defects	21
Accumulation of advanced oxidation protein products contributes to age-related impairment of gap junction intercellular communication in osteocytes of male mice	21
High-intensity running exercise promotes knee meniscal damage via the PI3K/AKT/mTOR axis	21
CXCR4 is a response gene for parathyroid hormone which affects osteoblast and osteoclast function in vitro	20
Transcriptome-wide association study identifies new susceptibility genes for degenerative cervical spondylosis	19
High-resolution peripheral quantitative CT of the proximal fifth metatarsal reveals microstructural similarity between Lawrence and Botte zones I and II	19
Hederagenin promotes SIRT6 to attenuate epidural scar formation by aggravating PRMT1 deacetylation	19
Navigating change: upholding scientific integrity in an era of innovation	19
A comparison of clinical and radiological outcomes between two different biodegradable local antibiotic carriers used in the single-stage surgical management of long bone osteomyelitis	18
Future registry research	18
Detection of rare microorganisms in bone and joint infections by metagenomic next-generation sequencing	17
Don’t mind the gap: reframing the Perren strain rule for fracture healing using insights from virtual mechanical testing	17
Detection limitations of bacteria in tissue samples	17
An analysis of the medial femoral condyle flap anatomy and the involvement of different tissue components for the reconstruction of complex defects	16
Induction heating combined with antibiotics or SAAP-148 effectively reduces biofilm-embedded Staphylococcus aureus on a fracture-related implant mimic	16
Longitudinal monitoring of bone remodelling activity around the acetabular cup after total hip arthroplasty using 18F-fluoride PET/CT scans	16
Diathermy and bone sawing are high aerosol yield procedures	15
Current therapeutic interventions combating biofilm-related infections in orthopaedics	15
Biomechanical study of screw-supported prosthesis in acetabular revision	15
Identification of age-related genes in rotator cuff tendon	15
Decreased Peli1 expression attenuates osteoarthritis by protecting chondrocytes and inhibiting M1-polarization of macrophages	15
siRNA incorporated in slow-release injectable hydrogel continuously silences DDIT4 and regulates nucleus pulposus cell pyroptosis through the ROS/TXNIP/NLRP3 axis to alleviate intervertebral disc dege	15
Reviewer acknowledgement	14
Proximal humerus fractures – epidemiology, comparison of mortality rates after surgical versus non-surgical treatment, and analysis of risk factors based on Medicare registry data	14
Overcoming barriers to interdisciplinary research in engineering and orthopaedic surgery	14
Modelling osteoarthritis in mice via surgical destabilization of the medial meniscus with or without a stereomicroscope	14
More severe joint disease and lower patient oxygenation are associated with less corrosive in vivo synovial fluid in patients with knee osteoarthritis	13
Panoramic heat map for spatial distribution of necrotic lesions	13
Preoperative prediction for periprosthetic bone loss and individual evaluation of bisphosphonate effect after total hip arthroplasty using artificial intelligence	13
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary hip arthroplasty in England and Wales	13
The role of AGEs in muscle ageing and sarcopenia	13
HDACi vorinostat protects muscle from degeneration after acute rotator cuff injury in mice	13
The diagnostic accuracy of serum and synovial inflammatory markers in chronic periprosthetic joint infection among anaemic patients	13
Impact of tranexamic acid on the efficacy of vancomycin and meropenem against periprosthetic joint infections	12
Correlation of cross-linking as measured by the trans-vinylene index and in vitro wear of polyethylene from various acetabular liner brands	12
The role of AGEs in pathogenesis of cartilage destruction in osteoarthritis	12
Incidence and risk factors of recurrence in limb osteomyelitis patients after antibiotic‐loaded cement spacer for definitive bone defect treatment	11
The complexity of decision-making for total hip arthroplasty in early osteoarthritis	11
Corrigendum	11
Cystic lesions in osteoarthritis and osteonecrosis of the femoral head	11
Overcoming floor and ceiling effects in knee arthroplasty outcome measurement	11
Developmental endothelial locus-1 attenuates palmitate-induced apoptosis in tenocytes through the AMPK/autophagy-mediated suppression of inflammation and endoplasmic reticulum stress	11
Anterior cruciate ligament remnant preservation attenuates apoptosis and enhances the regeneration of hamstring tendon graft	11
The prevalence and treatment of osteoporosis in patients undergoing total hip arthroplasty and the levels of biochemical markers of bone turnover	11
Defining the extracellular matrix in non-cartilage soft-tissues in osteoarthritis: a systematic review	11

Vascular remodelling and fibrotic changes in the joint capsule during periprosthetic knee infections	11
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary knee arthroplasty in England and Wales	11
Prioritization versus rationing of healthcare – elective surgery is not optional surgery	11
Three decades of transformation: a bibliometric study of gender and geographic trends in international orthopaedic journal publications	11
Urgent focus on enhanced recovery after surgery of AIDS patients with limb fractures	11
Impact of elevated sclerostin levels on bone resorption	11
Patellar luxation causes abnormal mechanical loading and joint destruction in the femoral-tibial joint	11
Osteocyte-specific dentin matrix protein 1	11
Mucin 1 aggravates synovitis and joint damage of rheumatoid arthritis by regulating inflammation and aggression of fibroblast-like synoviocytes	11
Anatomy changes, signalling pathways, and clinical treatment after ankle sprain	10
Increased local bone turnover in patients with chronic periprosthetic joint infection	10
Factors associated with Achilles tendon re-rupture following operative fixation	10
The role of Staphylococcus aureus small colony variants in intraosseous invasion and colonization in periprosthetic joint infection	10
Effect of human adipose stem cell-derived mitochondrial transplantation on the activity of chronically injured anterior cruciate ligament cells	10
Extended local release and improved bacterial eradication by adding rifampicin to a biphasic ceramic carrier containing gentamicin or vancomycin	10
Type-I and -II collagens from bone and cartilage colocalize at the osteochondral cement line	10
Femoral impingement in maximal hip flexion is anterior-inferior distal to the cam deformity in femoroacetabular impingement patients with femoral retroversion	10
Beta-caryophyllene prevents the defects in trabecular bone caused by Vitamin D deficiency through pathways instated by increased expression of klotho	10
Basic research for ultrasound-guided injection into skeletal muscle lesions in an experimental animal model	10
Single-cell transcriptomics analysis of the healing process of ligament rupture	10
Evaluating upper leg muscle volume	9
Achieved discharge outcome targets in patient-reported outcome measures after lower limb arthroplasty	9
Antiosteoporotic treatment promotes tendon-to-bone healing after rotator cuff repair	9
Efficacy of EDTA-NS irrigation in eradicating Staphylococcus aureus biofilm-associated infection	9
The role of neutrophils in the pathophysiology of knee osteoarthritis	9
Finite element analysis, biomechanics, and clinical advantages of percutaneous medial column screw reinforced locking plate in the treatment of complex distal femoral fractures	9
Biomechanical comparison between custom-made enhanced triflange and quadri-flange acetabular components for the treatment of Paprosky IIIB acetabular bone defects	9
The reconstruction of critical bone loss	9
Adenosine, lidocaine, and magnesium therapy augments joint tissue healing following experimental anterior cruciate ligament rupture and reconstruction	9
Rifampicin restores extracellular organic matrix formation and mineralization of osteoblasts after intracellular Staphylococcus aureus infection	8
Importance of posterior tibial slope in joint kinematics with an anterior cruciate ligament-deficient knee	8
The degenerated glenohumeral joint	8
Lateral unicompartmental knee arthroplasty is associated with nearer-normal gait characteristics and higher patient satisfaction compared to total knee arthroplasty	8
Qualitative methods: the missing link in orthopaedic research	8
Biomimetic tri-layered osteochondral scaffold	8
Long-term hypoxic atmosphere enhances the stemness, immunoregulatory functions, and therapeutic application of human umbilical cord mesenchymal stem cells	8
Effects of high antibiotic concentrations applied to continuous local antibiotic perfusion on human bone tissue-derived cells	8
Increased loading of the lateral knee compartment in the unamputated knee during gait in people with unilateral transfemoral/through-knee amputations	8
PEDF peptide plus hyaluronic acid stimulates cartilage regeneration in osteoarthritis via STAT3-mediated chondrogenesis	8
Overcoming the detrimental impact of volumetric muscle loss on segmental fracture healing via the induced membrane technique	8
Evaluation of the causal relationship between 28 circulating biomarkers and osteoarthritis	8
Effectiveness of mechanical cleaning, antibiotics, and induction heating on eradication of Staphylococcus aureus in mature biofilms	8
Development and validation of a novel prediction model for osteoporosis	8
The impact of cementing technique in polished taper fit hip stems	8
Growth differentiation factor 15 as a potential diagnostic biomarker for rheumatoid arthritis	8
TGF-β1 derived from macrophages contributes to load-induced tendon-bone healing in the murine rotator cuff repair model by promoting chondrogenesis	7
Reviewer acknowledgement	7
Dihydrocaffeic acid improves IL-1β-induced inflammation and cartilage degradation via inhibiting NF-κB and MAPK signalling pathways	7
Prospective clinical trial analyzing serum mast cell tryptase levels and arthrofibrosis rates after total knee arthroplasty	7
Transcutaneous carbon dioxide improves joint inflammation and articular cartilage degeneration in rat osteoarthritis models	7
Immunomodulatory role of T helper cells in rheumatoid arthritis	7
Efficacy of a saline wash plus vancomycin/tobramycin-doped PVA composite (PVA-VAN/TOB-P) in a mouse pouch infection model implanted with 3D-printed porous titanium cylinders	7
Intermittent parathyroid hormone increases stability and improves osseointegration of initially unstable implants	7
Clinical, oncological, and prognostic differences of patients with subsequent skeletal-related events in bone metastases	7
Identification of the molecular link: STAT3 is a shared key gene linking postmenopausal osteoporosis and sarcopenia	7
The interactions of macrophages, lymphocytes, and mesenchymal stem cells during bone regeneration	7
Infographic: Chongqing technique	7
Retraction notice	6
Meniscus cell lysate induces mitochondrial dysfunction of fibroblast-like synoviocytes via upregulating ANT3 in osteoarthritis	6
Complex network model reveals the positive effect of melatonin on bone parameters in rats with induced hypoestrogenism	6
Intra-articular versus systemic vancomycin for the treatment of periprosthetic joint infection after debridement and spacer implantation in a rat model	6
An immunoregenerative approach to mitigate post-traumatic osteoarthritis after intra-articular fracture	6
LncRNA PCBP1-AS1 induces osteoporosis by sponging miR-126-5p/PAK2 axis	6
The IMPACT of COVID-19 on trauma & orthopaedic surgery provides lessons for future communicable disease outbreaks	6
Genotype and phenotype correlation analysis in 27 families with multiple osteochondroma and validation by ATDC5 chondrocyte models	6
Comparison of the mechanical performance of intramedullary nail and locking plate in tibiotalocalcaneal arthrodesis	6
Stable polyethylene inlay fixation and low polyethylene wear rate in fixed-bearing total knee arthroplasty at five to six years’ follow-up	6
Ergothioneine prevents ovariectomy-induced osteoporosis by suppressing NF-κB/p65 signalling to attenuate osteoclastogenesis and bone marrow inflammation	6
Damage control orthopaedics is associated with impaired fracture healing and delayed recovery in a rodent model of severe multiple trauma	6
Infographic: Total hip arthroplasty in early osteoarthritis	6
Development of a new treatment for osteoporotic vertebral fractures using adipose-derived stem cell spheroids	6
Astragalus polysaccharide promotes osteogenic differentiation of human bone marrow derived mesenchymal stem cells by facilitating ANKFY1 expression through miR-760 inhibition	6
Alcohol-induced inhibition of bone formation and neovascularization contributes to the failure of fracture healing via the miR-19a-3p/FOXF2 axis	6
Integrating genome-wide association study with regulatory SNP annotations identified novel candidate genes for osteoporosis	6
Finite element study of the role of medial longitudinal arch in hallux valgus deformity	6
Identification of mechanics-responsive osteocyte signature in osteoarthritis subchondral bone	6
Changes in the shape of the lumbar curve during growth	5
Predicted waiting times for orthopaedic surgery	5
Aberrant anabolism hinders constructive metabolism of chondrocytes by pharmacotherapy in osteoarthritis	5
Effect of secretory leucocyte protease inhibitor on early tendon-to-bone healing after anterior cruciate ligament reconstruction in a rat model	5

The role of BioFire Joint Infection Panel in diagnosing periprosthetic hip and knee joint infections in patients with unclear conventional microbiological results	5
Cytokines and regulatory T cells in ankylosing spondylitis	5
Are we doing the right surgical trials?	5
Volume and location of bone regeneration after autologous expanded mesenchymal stromal cells in hip osteonecrosis	5
Multiple roles of ALK3 in osteoarthritis	5
Rapid multiplex micro-ELISA assay for simultaneous measurement of synovial biomarkers	5
Appraising causal risk and protective factors for rheumatoid arthritis	5
Quantitative evaluation of cervical muscles in patients with degenerative cervical myelopathy using diffusion tensor imaging metrics	5
Arthroscopic cam resection reduces femoroacetabular contact pressure	5
A bilayer scaffold of collagen and nanohydroxyapatite promotes osteochondral defect repair in rabbit knee joints	5
Melatonin protects human nucleus pulposus cells from pyroptosis by regulating Nrf2 via melatonin membrane receptors	5
Cry2 prompts clock oscillation and temporomandibular joint homeostasis under mechanical loading	5
Repurposing the diuretic benzamil as an anti-osteosarcoma agent that acts by suppressing integrin/FAK/STAT3 signalling and compromising mitochondrial function	5
Meaningful values in the Short Form Health Survey-36 after total knee arthroplasty – an alternative to the EuroQol five-dimension index as a measure for health-related quality of life	5
Expression of Concern	5
Regeneration of injured articular cartilage using the recombinant human amelogenin protein	5
Repetitive combined doses of bacteriophages and gentamicin protect against Staphylococcus aureus implant-related infections in Galleria mellonella	5
Abnormal mechanical stress due to excessive femoral torsion is associated with dysplasia of the distal femoral epiphyseal plate and trochlea	4
The Clinical Practice Integration of Artificial Intelligence (CPI-AI) framework	4
Effect of treadmill training on fibrocartilage complex repair in tendon-bone insertion healing in the postinflammatory stage	4
Wound fluid ceftriaxone concentrations after local application with calcium sulphate as carrier material in the treatment of orthopaedic device-associated hip infections	4
Concomitant osteochondral lesion of the talus affects in vivo ankle kinetics in patients with chronic ankle instability	4
Enhancement of hyaline cartilage and subchondral bone regeneration in a rat osteochondral defect model through focused extracorporeal shockwave therapy	4
Biomechanical evaluation of asymmetric metaphyseal cone applications for lateral tibial plateau fractures	4
Knee kinematics during staircase descent	4
Development and validation of an open-source tool for opportunistic screening of osteoporosis from hip CT images	4
Melatonin induces RAW264.7 cell apoptosis via the BMAL1/ROS/MAPK-p38 pathway to improve postmenopausal osteoporosis	4
Cyclin D1 mediates pain behaviour in a rat model of breast cancer-induced bone pain by a mechanism involving regulation of the proliferation of spinal microglia	4
Tendon healing: a concise review on cellular and molecular mechanisms with a particular focus on the Achilles tendon	4
Pulsed Nd:YAG laser therapy accelerates fracture healing in a rat femoral osteotomy model	4
Monomeric CRP regulates inflammatory responses in human intervertebral disc cells	4
In vivo reduction of biofilm seeded on orthopaedic implants	4
Upregulated ribosome pathway plays a key role in HDAC4, improving the survival rate and biofunction of chondrocytes	4
The role of EDIL3 in maintaining cartilage extracellular matrix and inhibiting osteoarthritis development	4
Clinical efficacy and safety of P-15 peptide enhanced bone graft substitute in surgical bone regenerative procedures in adult maxillofacial, spine, and trauma patients	4
Enhanced antibiofilm potential of low-intensity pulsed ultrasound combined with 0.35% povidone-iodine in a rat model of periprosthetic joint infection	4