OOIR: Observatory of International Research

Papers

(The TQCC of Bone & Joint Research is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Mechanical influence of facet tropism in patients with chronic discogenic pain disorder	92
Systemic glucose-insulin-potassium reduces skeletal muscle injury, kidney injury, and pain in a murine ischaemia-reperfusion model	64
Osteoporosis: current screening methods, novel techniques, and preoperative assessment of bone mineral density	62
The effect of ethnicity on the age-related changes of spinopelvic characteristics: a systematic review	56
Mental health implications of fracture-related infections	51
Comparison of periprosthetic femoral fracture torque and strain pattern of three types of femoral components in experimental model	49
Candy box technique with sutures and Nice knot	48
Intra-articular celecoxib improves knee extension regardless of surgical release in a rabbit model of arthrofibrosis	39
Bi-unicondylar arthroplasty	38
Prognostic factors associated with failure of total elbow arthroplasty	38
Classification of distinct osteoarthritis subtypes with different knee joint tissues by gene expression profiles	33
Effect of the additional anteroposterior blocking screw on nail/medullary canal mismatch after cephalomedullary nailing in unstable pertrochanteric fracture	33
Cartilage oligomeric matrix protein as a potential biomarker for knee osteoarthritis	32
Defining the optimal position of the lipped liner in combination with cup orientation and stem version	32
The metabolic equivalent of task score	29
Can severity of trunnion damage be estimated by visual inspection alone?	29
Exosomes from dysfunctional chondrocytes affect osteoarthritis in Sprague-Dawley rats through FTO-dependent regulation of PIK3R5 mRNA stability	28
Diagnosing periprosthetic joint infections	27
Finite element analysis safety of tibial cortex transverse transport	26
Osteochondral lesions of talus	26
The CREB1 inhibitor 666-15 maintains cartilage homeostasis and mitigates osteoarthritis progression	24
Sheep condyle model evaluation of bone marrow cell concentrate combined with a scaffold for repair of large osteochondral defects	24
Prediction of implant failure risk due to periprosthetic femoral fracture after primary elective total hip arthroplasty	24
Preoperative measures of bone mineral density from digital wrist radiographs	23
Comprehensive analysis of pathological changes in hip joint capsule of patients with developmental dysplasia of the hip	23

Application of loaded graphene oxide biomaterials in the repair and treatment of bone defects	22
The role of cells and signal pathways in subchondral bone in osteoarthritis	21
Molecular crosstalk between articular cartilage, meniscus, synovium, and subchondral bone in osteoarthritis	21
Orientin alleviates chondrocyte senescence and osteoarthritis by inhibiting PI3K/AKT pathway	21
Don’t mind the gap: reframing the Perren strain rule for fracture healing using insights from virtual mechanical testing	20
CXCR4 is a response gene for parathyroid hormone which affects osteoblast and osteoclast function in vitro	20
Beyond the surface: anterior cruciate ligament assessment in knee osteoarthritis	20
Future registry research	19
A comparison of clinical and radiological outcomes between two different biodegradable local antibiotic carriers used in the single-stage surgical management of long bone osteomyelitis	19
Histone deacetylase inhibitors attenuated interleukin-1β-induced chondrogenesis inhibition in synovium-derived mesenchymal stem cells of the temporomandibular joint	19
Detection of rare microorganisms in bone and joint infections by metagenomic next-generation sequencing	18
Tibial cortex transverse transport accelerates wound healing via enhanced angiogenesis and immunomodulation	18
Transcriptome-wide association study identifies new susceptibility genes for degenerative cervical spondylosis	18
Human acellular amniotic membrane scaffolds encapsulating juvenile cartilage fragments accelerate the repair of rabbit osteochondral defects	18
Cyclooxygenase-2 negatively regulates osteogenic differentiation in murine bone marrow mesenchymal stem cells via the FOXO3a/p27^kip1 pathway	17
Hederagenin promotes SIRT6 to attenuate epidural scar formation by aggravating PRMT1 deacetylation	17
Induction heating combined with antibiotics or SAAP-148 effectively reduces biofilm-embedded Staphylococcus aureus on a fracture-related implant mimic	16
Accumulation of advanced oxidation protein products contributes to age-related impairment of gap junction intercellular communication in osteocytes of male mice	16
Decreased Peli1 expression attenuates osteoarthritis by protecting chondrocytes and inhibiting M1-polarization of macrophages	16
siRNA incorporated in slow-release injectable hydrogel continuously silences DDIT4 and regulates nucleus pulposus cell pyroptosis through the ROS/TXNIP/NLRP3 axis to alleviate intervertebral disc dege	16
Paclitaxel-mediated microtubule stabilization regulates flexor tendon repair in rats	16
Ultrasound-targeted simvastatin-loaded microbubble destruction promotes OA cartilage repair by modulating the cholesterol efflux pathway mediated by PPARγ in rabbits	16
Detection limitations of bacteria in tissue samples	16
A large-scale genetic correlation scan between rheumatoid arthritis and human plasma protein	15
Identification of age-related genes in rotator cuff tendon	15
Diathermy and bone sawing are high aerosol yield procedures	15
Current therapeutic interventions combating biofilm-related infections in orthopaedics	14
Proximal humerus fractures – epidemiology, comparison of mortality rates after surgical versus non-surgical treatment, and analysis of risk factors based on Medicare registry data	14
Modelling osteoarthritis in mice via surgical destabilization of the medial meniscus with or without a stereomicroscope	14
Do preoperative intra-articular injections of corticosteroids or hyaluronic acid increase the risk of infection after total knee arthroplasty? A meta-analysis	14
Capsular ligaments provide a passive stabilizing force to protect the hip against edge loading	13
Reviewer acknowledgement	13
Panoramic heat map for spatial distribution of necrotic lesions	13
Development and validation of a modularized external fixator for generating standardized fracture healing micromotions in rats	13
Infographic: Osteoimmunology mechanism of osteonecrosis of the femoral head	13
HDACi vorinostat protects muscle from degeneration after acute rotator cuff injury in mice	13
The role of AGEs in pathogenesis of cartilage destruction in osteoarthritis	12
The complexity of decision-making for total hip arthroplasty in early osteoarthritis	12
Correlation of cross-linking as measured by the trans-vinylene index and in vitro wear of polyethylene from various acetabular liner brands	12
The role of AGEs in muscle ageing and sarcopenia	12
Urgent focus on enhanced recovery after surgery of AIDS patients with limb fractures	12
Incidence and risk factors of recurrence in limb osteomyelitis patients after antibiotic‐loaded cement spacer for definitive bone defect treatment	12
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary hip arthroplasty in England and Wales	12
Preoperative prediction for periprosthetic bone loss and individual evaluation of bisphosphonate effect after total hip arthroplasty using artificial intelligence	12
Anterior cruciate ligament remnant preservation attenuates apoptosis and enhances the regeneration of hamstring tendon graft	12
Defining the extracellular matrix in non-cartilage soft-tissues in osteoarthritis: a systematic review	11
The effect of cement augmentation on pedicle screw fixation under various load cases	11
Corrigendum	11
Impact of tranexamic acid on the efficacy of vancomycin and meropenem against periprosthetic joint infections	11
The prevalence and treatment of osteoporosis in patients undergoing total hip arthroplasty and the levels of biochemical markers of bone turnover	11

Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary knee arthroplasty in England and Wales	10
Human osteoblasts obtained from distinct periarticular sites demonstrate differences in biological function in vitro	10
Type-I and -II collagens from bone and cartilage colocalize at the osteochondral cement line	10
Femoral impingement in maximal hip flexion is anterior-inferior distal to the cam deformity in femoroacetabular impingement patients with femoral retroversion	10
Impact of elevated sclerostin levels on bone resorption	10
Overcoming floor and ceiling effects in knee arthroplasty outcome measurement	10
Developmental endothelial locus-1 attenuates palmitate-induced apoptosis in tenocytes through the AMPK/autophagy-mediated suppression of inflammation and endoplasmic reticulum stress	10
Basic research for ultrasound-guided injection into skeletal muscle lesions in an experimental animal model	10
Prioritization versus rationing of healthcare – elective surgery is not optional surgery	10
Mucin 1 aggravates synovitis and joint damage of rheumatoid arthritis by regulating inflammation and aggression of fibroblast-like synoviocytes	10
Factors associated with Achilles tendon re-rupture following operative fixation	10
Osteocyte-specific dentin matrix protein 1	10
Single-cell transcriptomics analysis of the healing process of ligament rupture	10
Exercise modifies the disease-relevant gut microbial shifts in post-traumatic osteoarthritis rats	9
Evaluation of the causal relationship between 28 circulating biomarkers and osteoarthritis	9
Adenosine, lidocaine, and magnesium therapy augments joint tissue healing following experimental anterior cruciate ligament rupture and reconstruction	9
Effect of resistance training on satellite cells in old mice – a transcriptome study	9
The role of Staphylococcus aureus small colony variants in intraosseous invasion and colonization in periprosthetic joint infection	9
Evaluating upper leg muscle volume	9
Extended local release and improved bacterial eradication by adding rifampicin to a biphasic ceramic carrier containing gentamicin or vancomycin	9
Beta-caryophyllene prevents the defects in trabecular bone caused by Vitamin D deficiency through pathways instated by increased expression of klotho	9
The reconstruction of critical bone loss	9
Increased local bone turnover in patients with chronic periprosthetic joint infection	9
Efficacy of EDTA-NS irrigation in eradicating Staphylococcus aureus biofilm-associated infection	9