OOIR: Observatory of International Research

Papers

(The TQCC of Bone & Joint Research is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Mental health implications of fracture-related infections	89
Intra-articular celecoxib improves knee extension regardless of surgical release in a rabbit model of arthrofibrosis	61
Mechanical influence of facet tropism in patients with chronic discogenic pain disorder	60
Comparison of periprosthetic femoral fracture torque and strain pattern of three types of femoral components in experimental model	53
Osteoporosis: current screening methods, novel techniques, and preoperative assessment of bone mineral density	47
Systemic glucose-insulin-potassium reduces skeletal muscle injury, kidney injury, and pain in a murine ischaemia-reperfusion model	47
The effect of ethnicity on the age-related changes of spinopelvic characteristics: a systematic review	46
Prognostic factors associated with failure of total elbow arthroplasty	41
Can severity of trunnion damage be estimated by visual inspection alone?	39
Defining the optimal position of the lipped liner in combination with cup orientation and stem version	38
The metabolic equivalent of task score	36
Exosomes from dysfunctional chondrocytes affect osteoarthritis in Sprague-Dawley rats through FTO-dependent regulation of PIK3R5 mRNA stability	33
Effect of the additional anteroposterior blocking screw on nail/medullary canal mismatch after cephalomedullary nailing in unstable pertrochanteric fracture	32
Diagnosing periprosthetic joint infections	31
Cartilage oligomeric matrix protein as a potential biomarker for knee osteoarthritis	29
Classification of distinct osteoarthritis subtypes with different knee joint tissues by gene expression profiles	29
Bi-unicondylar arthroplasty	29
Molecular crosstalk between articular cartilage, meniscus, synovium, and subchondral bone in osteoarthritis	28
Prediction of implant failure risk due to periprosthetic femoral fracture after primary elective total hip arthroplasty	27
Finite element analysis safety of tibial cortex transverse transport	27
Osteochondral lesions of talus	27
The CREB1 inhibitor 666-15 maintains cartilage homeostasis and mitigates osteoarthritis progression	26
Sheep condyle model evaluation of bone marrow cell concentrate combined with a scaffold for repair of large osteochondral defects	25
Preoperative measures of bone mineral density from digital wrist radiographs	24
The role of cells and signal pathways in subchondral bone in osteoarthritis	23

Orientin alleviates chondrocyte senescence and osteoarthritis by inhibiting PI3K/AKT pathway	23
Comprehensive analysis of pathological changes in hip joint capsule of patients with developmental dysplasia of the hip	23
Don’t mind the gap: reframing the Perren strain rule for fracture healing using insights from virtual mechanical testing	22
Application of loaded graphene oxide biomaterials in the repair and treatment of bone defects	22
Cyclooxygenase-2 negatively regulates osteogenic differentiation in murine bone marrow mesenchymal stem cells via the FOXO3a/p27^kip1 pathway	21
Beyond the surface: anterior cruciate ligament assessment in knee osteoarthritis	21
Hederagenin promotes SIRT6 to attenuate epidural scar formation by aggravating PRMT1 deacetylation	20
Accumulation of advanced oxidation protein products contributes to age-related impairment of gap junction intercellular communication in osteocytes of male mice	19
CXCR4 is a response gene for parathyroid hormone which affects osteoblast and osteoclast function in vitro	19
Histone deacetylase inhibitors attenuated interleukin-1β-induced chondrogenesis inhibition in synovium-derived mesenchymal stem cells of the temporomandibular joint	19
A comparison of clinical and radiological outcomes between two different biodegradable local antibiotic carriers used in the single-stage surgical management of long bone osteomyelitis	19
Future registry research	19
Detection of rare microorganisms in bone and joint infections by metagenomic next-generation sequencing	18
Transcriptome-wide association study identifies new susceptibility genes for degenerative cervical spondylosis	18
Human acellular amniotic membrane scaffolds encapsulating juvenile cartilage fragments accelerate the repair of rabbit osteochondral defects	18
Detection limitations of bacteria in tissue samples	17
Decreased Peli1 expression attenuates osteoarthritis by protecting chondrocytes and inhibiting M1-polarization of macrophages	17
Tibial cortex transverse transport accelerates wound healing via enhanced angiogenesis and immunomodulation	17
Proximal humerus fractures – epidemiology, comparison of mortality rates after surgical versus non-surgical treatment, and analysis of risk factors based on Medicare registry data	16
Ultrasound-targeted simvastatin-loaded microbubble destruction promotes OA cartilage repair by modulating the cholesterol efflux pathway mediated by PPARγ in rabbits	16
siRNA incorporated in slow-release injectable hydrogel continuously silences DDIT4 and regulates nucleus pulposus cell pyroptosis through the ROS/TXNIP/NLRP3 axis to alleviate intervertebral disc dege	16
Diathermy and bone sawing are high aerosol yield procedures	15
Current therapeutic interventions combating biofilm-related infections in orthopaedics	15
A large-scale genetic correlation scan between rheumatoid arthritis and human plasma protein	15
Induction heating combined with antibiotics or SAAP-148 effectively reduces biofilm-embedded Staphylococcus aureus on a fracture-related implant mimic	15
Modelling osteoarthritis in mice via surgical destabilization of the medial meniscus with or without a stereomicroscope	15
Identification of age-related genes in rotator cuff tendon	15
Do preoperative intra-articular injections of corticosteroids or hyaluronic acid increase the risk of infection after total knee arthroplasty? A meta-analysis	15
Panoramic heat map for spatial distribution of necrotic lesions	14
Development and validation of a modularized external fixator for generating standardized fracture healing micromotions in rats	14
HDACi vorinostat protects muscle from degeneration after acute rotator cuff injury in mice	14
Preoperative prediction for periprosthetic bone loss and individual evaluation of bisphosphonate effect after total hip arthroplasty using artificial intelligence	14
Reviewer acknowledgement	14
Infographic: Osteoimmunology mechanism of osteonecrosis of the femoral head	13
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary hip arthroplasty in England and Wales	13
Capsular ligaments provide a passive stabilizing force to protect the hip against edge loading	13
The role of AGEs in pathogenesis of cartilage destruction in osteoarthritis	13
Anterior cruciate ligament remnant preservation attenuates apoptosis and enhances the regeneration of hamstring tendon graft	12
The effect of cement augmentation on pedicle screw fixation under various load cases	12
Corrigendum	12
Urgent focus on enhanced recovery after surgery of AIDS patients with limb fractures	12
Impact of tranexamic acid on the efficacy of vancomycin and meropenem against periprosthetic joint infections	12
The prevalence and treatment of osteoporosis in patients undergoing total hip arthroplasty and the levels of biochemical markers of bone turnover	12
The complexity of decision-making for total hip arthroplasty in early osteoarthritis	12
Correlation of cross-linking as measured by the trans-vinylene index and in vitro wear of polyethylene from various acetabular liner brands	12
Incidence and risk factors of recurrence in limb osteomyelitis patients after antibiotic‐loaded cement spacer for definitive bone defect treatment	12
The role of AGEs in muscle ageing and sarcopenia	12
Hsa_circ_0066523 promotes the proliferation and osteogenic differentiation of bone mesenchymal stem cells by repressing PTEN	11
Impact of elevated sclerostin levels on bone resorption	11
Overcoming floor and ceiling effects in knee arthroplasty outcome measurement	11

Defining the extracellular matrix in non-cartilage soft-tissues in osteoarthritis: a systematic review	11
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary knee arthroplasty in England and Wales	11
Developmental endothelial locus-1 attenuates palmitate-induced apoptosis in tenocytes through the AMPK/autophagy-mediated suppression of inflammation and endoplasmic reticulum stress	10
Osteocyte-specific dentin matrix protein 1	10
Efficacy of EDTA-NS irrigation in eradicating Staphylococcus aureus biofilm-associated infection	10
Prioritization versus rationing of healthcare – elective surgery is not optional surgery	10
Factors associated with Achilles tendon re-rupture following operative fixation	10
Single-cell transcriptomics analysis of the healing process of ligament rupture	10
Basic research for ultrasound-guided injection into skeletal muscle lesions in an experimental animal model	10
Mucin 1 aggravates synovitis and joint damage of rheumatoid arthritis by regulating inflammation and aggression of fibroblast-like synoviocytes	10
Human osteoblasts obtained from distinct periarticular sites demonstrate differences in biological function in vitro	10
The reconstruction of critical bone loss	10
Femoral impingement in maximal hip flexion is anterior-inferior distal to the cam deformity in femoroacetabular impingement patients with femoral retroversion	10
Evaluation of the causal relationship between 28 circulating biomarkers and osteoarthritis	9
The role of Staphylococcus aureus small colony variants in intraosseous invasion and colonization in periprosthetic joint infection	9
Extended local release and improved bacterial eradication by adding rifampicin to a biphasic ceramic carrier containing gentamicin or vancomycin	9
Exercise modifies the disease-relevant gut microbial shifts in post-traumatic osteoarthritis rats	9
Long-term hypoxic atmosphere enhances the stemness, immunoregulatory functions, and therapeutic application of human umbilical cord mesenchymal stem cells	9
Evaluating upper leg muscle volume	9
Adenosine, lidocaine, and magnesium therapy augments joint tissue healing following experimental anterior cruciate ligament rupture and reconstruction	9
Beta-caryophyllene prevents the defects in trabecular bone caused by Vitamin D deficiency through pathways instated by increased expression of klotho	9
Increased local bone turnover in patients with chronic periprosthetic joint infection	9
Rifampicin restores extracellular organic matrix formation and mineralization of osteoblasts after intracellular Staphylococcus aureus infection	9
Augmentation of implant surfaces with BMP-2 in a revision setting	9
Effect of resistance training on satellite cells in old mice – a transcriptome study	9