Biology Open

Article	Citations
Fast & Fair peer review: a bold experiment in scientific publishing	46
Hip stabilization in an australopithecine-like hip: the influence of shape on muscle activation	36
Over-expressing NadA quinolinate synthase inEscherichia colienhances the bioelectrochemistry in microbial fuel cells	34
Chromosomal organization of multigene families and meiotic analysis in species of Loricariidae (Siluriformes) from Brazilian Amazon, with description of a new cytotype for genus Spatuloricaria	30
Macrophages allocate before apoptosis initiation and produce reactive oxygen species during interdigital phagocytosis	28
Concrete consequences: construction on prime honey bee habitat doubles foraging distances	25
EyeHex toolbox for complete segmentation of ommatidia in fruit fly eyes	24
Reorganization of the heterochromatin-associated gene-dense subcompartment in early neuronal development	24
A year at the forefront of plasmodesmal biology	23
Knee position affects medial gastrocnemius and soleus activation during dynamic plantarflexion: no evidence for an inter-muscle compensation in healthy young adults	22
First person – Rajeshwari B. R.	21
First person – Daisy Pineda-Suazo	20
Unpredictable aggressive defence of the venomous snake, Crotalus ravus, towards predators and humans	19
The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut	19
Divalent metal content in diet affects severity of manganese toxicity in Drosophila	19
Primary human neutrophils and monocytes migrate along endothelial cell boundaries to optimize search efficiency under static in vitro conditions	19
Local differences in robustness to ocean acidification	17
shRNAs targeting mouseAdam10diminish cell response to proinflammatory stimuli independently ofAdam10silencing	16
Cuticular microstructure of the locust femur–tibia joint	16
First person – Franziska Hacker	16
EFEMP1 contributes to light-dependent ocular growth in zebrafish	15
Manipulating mitochondrial reactive oxygen species alters survival in unexpected ways in a Drosophila Cdk5 model of neurodegeneration	15
Young minds, deeper insights: a recap of the BMAS Summer School 2023, ranging from basic research to clinical implications of bone marrow adipose tissue	15
Fluorescent protein tags for human tropomyosin isoform comparison	15
An experimental test of chronic traffic noise exposure on parental behaviour and reproduction in zebra finches	15

Ccn2a acts downstream of cx43 to influence joint formation during zebrafish fin regeneration	14
Empowering tomorrow's leaders: the impact of the 15th Network of Young Researchers in Andrology (NYRA) meeting on male reproductive health and interdisciplinary collaboration	14
The Endosomal Sorting Complex, ESCRT, has diverse roles in blood progenitor maintenance, lineage choice and immune response	13
Retraction: Overexpression of long non-coding RNA SBF2-AS1 promotes cell progression in esophageal squamous cell carcinoma (ESCC) by repressing miR-494 to up-regulate PFN2 expression	13
NANOS3 suppresses premature spermatogonial differentiation to expand progenitors and fine-tunes spermatogenesis in mice	13
Dynamic shapes of the zygote and two-cell mouse and human	13
Rhoptry kinase protein 39 (ROP39) is a novel factor that recruits host mitochondria to the parasitophorous vacuole of Toxoplasma gondii	12
Future leader to watch – Tania Martins-Marques	12
The importance of considering regulatory domains in genome-wide analyses – the nearest gene is often wrong!	12
Shaping the future of male reproductive health: fostering talent at the 14th Network of Young Researchers in Andrology meeting	11
First person – Mikaela Scheer	11
Correction: Stable atrogin-1 (Fbxo32) and MuRF1 (Trim63) gene expression is involved in the protective mechanism in soleus muscle of hibernating Daurian ground squirrels (<	11
First person – Angela Fan and Yoldas Yildiz	11
The relationship between locomotion and hindlimb morphology in the leopard (Panthera pardus) using a geometric morphometric approach	11
First person – Tom Carruthers	11
Feeding a rich diet supplemented with the translation inhibitor cycloheximide decreases lifespan and ovary size in Drosophila	10
First person – Avery Hinks	10
Fully automated point spread function analysis using PyCalibrate	10
From fossils to future – Jane Francis on polar exploration and changing climates	10
Parental exposure to ocean acidification impacts gamete production and physiology but not offspring performance in Nematostella vectensis	10
Differential effect of ubiquitous and germline depletion of Integrator complex function on C. elegans physiology	10
The Abl-interactor Abi suppresses the function of the BRAG2 GEF family member Schizo	9
Social interactions among ants are impacted by food availability and group size	9
Metabolic shift towards oxidative phosphorylation reduces cell-density-induced cancer-stem-cell-like characteristics in prostate cancer in vitro	9
Dorso-ventral heterogeneity in tracheal basal stem cells	9
Ethanol downregulates gastrula gene expression and cell movement, causing symptoms of foetal alcohol spectrum disorders	9
Effects of blood extraction and ecophysiological experiments on stress in adult males of Liolaemus attenboroughi	9
Bees display limited acclimation capacity for heat tolerance	9
Hotter deserts and the impending challenges for the spiny-tailed Lizard in India	9
Holding time has limited impact on constitutive innate immune function in a long-lived Antarctic seabird, the Adélie penguin: implications for field studies	9
Winging it: hummingbirds alter flying kinematics during molt	9
Cellular senescence limits translational readthrough	9
First person – Leah Eller	9
Normotensive metabolic syndrome in Transient Receptor Potential Canonical Channel type 1 Trpc1−/− mice.	9
Investigating the link between morphological characteristics and diet in an island population of omnivorous reptiles (Sphenodon punctatus)	8
Glycogen synthase is required for heat shock-mediated autophagy induction in neuronal cells	8
Protein complexes from mouse and chick brain that interact with phospho-KXGS motif tau/microtubule associated protein antibody	8
Pacsin2 is required for endocytosis in the zebrafish pronephric tubule	8
Na,K-ATPase activity promotes macropinocytosis in colon cancer via Wnt signaling	8
Neural crest development and disorders: from patient to model system and back again – the NEUcrest conference	8
Mutational cooperativity of RUNX1::RUNX1T1 isoform 9a and oncogenic NRAS in zebrafish myeloid leukaemia	8
Meeting proceedings of the 43rd Indian Association for Cancer Research (IACR)	8
ASCL2 is a key regulator of the proliferation–differentiation equilibrium in the esophageal epithelium	8
Response to Correspondence: Hajnal et al. ‘The role of lin-12 notch in C. elegans anchor cell proliferation’	8
Frequency-dependent avoidance movement of glass catfish in response to sinusoidal electrical stimulation and associated spiking patterns of electroreceptors	8
Aging disrupts spatiotemporal regulation of germline stem cells and niche integrity	8
Euglena International Network (EIN): Driving euglenoid biotechnology for the benefit of a challenged world	8
Zika virus-induces metabolic alterations in fetal neuronal progenitors that could influence in neurodevelopment during early pregnancy	8
The zebrafish ETS transcription factor Fli1b functions upstream of Scl/Tal1 during embryonic hematopoiesis	8
Intrinsic function of the peptidylarginine deiminase PADI4 is dispensable for normal haematopoiesis	8

Arf6 is necessary for senseless expression in response to wingless signalling during Drosophila wing development	7
Reliable replicative lifespan determination of yeast with a single-channel microfluidic chip	7
Antimicrobial peptide expression in the cockroach gut during enterobacterial infection is specific and influenced by type III secretion	7
Insights into Octopus maya cathepsins from metatranscriptome and genome: structure evolutionary relationships and functional role prediction in digestive processes	7
Investigating the effect of cholinergic and adrenergic blocking agents on maternal-fetal heart rates and their interactions in mice fetuses	7
Temporal integration and decision-making in crocodiles	7
Retraction: Overexpression of Wnt7a enhances radiosensitivity of non-small-cell lung cancer via the Wnt/JNK pathway	7
Computational anatomy and geometric shape analysis enables analysis of complex craniofacial phenotypes in zebrafish	7
Morphlight theory inspired by raptors: musculoskeletal modeling and muscle control in Falco peregrinus wing flapping	7
Hormonal regulation of miRNA during mammary gland development	7
CDX2 dose-dependently influences the gene regulatory network underlying human extraembryonic mesoderm development	7
Characterization of nuclear pore complex targeting domains in Pom152 in Saccharomyces cerevisiae	7
Single-motor and multi-motor motility properties of kinesin-6 family members	7
Changes in mitochondrial distribution occur at the axon initial segment in association with neurodegeneration in Drosophila	7
Nondeterministic nature of sensorineural outcomes following noise trauma	7
An optimized retroviral toolbox for overexpression and genetic perturbation of primary lymphocytes	6
Coilin as a regulator of NF-kB mediated inflammation in preeclampsia	6
A Drosophila model of mitochondrial disease phenotypic heterogeneity	6
SOX2 and NR2F1 coordinate the gene expression program of the early postnatal visual thalamus	6
First person – Kelly Diamond	6
Experimental short-term heatwaves negatively impact body weight gain and survival during larval development in Bombus terrestris L. (Hymenoptera: Apidae)	6
Intermittent hypoxia differentially affects metabolic and oxidative stress responses in two species of cyprinid fish	6
microRNA-guided immunity against respiratory virus infection in human and mouse lung cells	6
Actin cytoskeleton in angiogenesis	6
Biomechanical analysis of little penguins’ underwater locomotion from the free-ranging dive data	6
Retraction: MicroRNA-96-5p promotes proliferation, invasion and EMT of oral carcinoma cells by directly targeting FOXF2	6
A novel technique for atraumatic transurethral catheterisation of male rats	6
Metabolic scaling of fire ants (Solenopsis invicta) engaged in collective behaviors	6
Loss of Elp1 perturbs histone H2A.Z and the Notch signaling pathway	6
Interaction between Discs large and Pins/LGN/GPSM2: a comparison across species	6
Regulation of NANOG and SOX2 expression by activin A and a canonical WNT agonist in bovine embryonic stem cells and blastocysts	6
Cerebral organoids in primary progressive multiple sclerosis reveal stem cell and oligodendrocyte differentiation defect	6
Characterization of alternative splicing during mammalian brain development reveals the extent of isoform diversity and potential effects on protein structural changes	6
Maintenance of neuronal fate and transcriptional identity	6
Partial role of volatile organic compounds in behavioural responses of mice to bedding from cancer-affected congeners	6
Increased expression of the small lysosomal gene SVIP in the Drosophila gut suppresses pathophysiological features associated with a high-fat diet	6
Vestigial-dependent induction contributes to robust patterning but is not essential for wing-fate recruitment in Drosophila	6
Wnt and BMP signalling direct anterior–posterior differentiation in aggregates of mouse embryonic stem cells	6
Effects of vessel noise on beluga (Delphinapterus leucas) call type use: ultrasonic communication as an adaptation to noisy environments?	6
Innervation of the developing kidney in vivo and in vitro	6
Zebrafish embryos hatch early in response to chemical and mechanical indicators of predation risk, resulting in underdeveloped swimming ability of hatchling larvae	6
Vitamin A cycle byproducts explain retinal damage and molecular changes thought to initiate retinal degeneration	6
Alterations in lifespan and sleep:wake duration under selective monochromes of visible light in Drosophila melanogaster	6
Experimental playback of urban noise does not affect cognitive performance in captive Australian magpies	6
Deletion of taf1 and taf5 in zebrafish capitulate cardiac and craniofacial abnormalities associated with TAFopathies through perturbations in metabolism	6
First person – Emily Bulger	6
First person – Latasha Ludwig	6
Cdc48 and its co-factor Ufd1 extract CENP-A from centromeric chromatin and can induce chromosome elimination in the fission yeast Schizosaccharomyces pombe	5
Reevaluating the relationship between EGL-43 (EVI1) and LIN-12 (Notch) during C. elegans anchor cell invasion	5
First person – Francesca Mastropasqua and Marika Oksanen	5
Developmental expression patterns of toolkit genes in male accessory gland ofDrosophilaparallels those of mammalian prostate	5
exTREEmaTIME: a method for incorporating uncertainty into divergence time estimates	5
Identification of a new allele of O-fucosyltransferase 1 involved in Drosophila intestinal stem cell regulation	5
Tbx5 overexpression in embryoid bodies increases TAK1 expression but does not enhance the differentiation of sinoatrial node cardiomyocytes	5
Development of a cypovirus protein microcrystal-encapsulated Bacillus thuringiensis UV-tolerant and mosquitocidal δ-endotoxin	5
Gene expression and DNA methylation changes in response to hypoxia in toxicant-adapted Atlantic killifish (Fundulus heteroclitus)	5
Alpha-T-catenin is expressed in peripheral nerves as a constituent of Schwann cell adherens junctions	5
Ethanol induces subcellular trafficking of the RNA-binding protein, hnRNP A1, in neuronal cells in vitro, but not in the peripubertal rat brain	5
Sox8: a multifaceted transcription factor in development and disease	5
BBQ methods: streamlined workflows for bacterial burden quantification in infected cells by confocal microscopy	5
Expression levels and activities of energy-yielding ATPases in the oligohaline neritid snail Theodoxus fluviatilis under changing environmental salinities	5
Introducing Daniel Gorelick – a new Editor-in-Chief for Biology Open	5
Saccharomyces cerevisiae deficient in the early anaphase release of Cdc14 can traverse anaphase I without ribosomal DNA disjunction and successfully complete meiosis	5
First person – Amy Irving	5
Plpp3, a novel regulator of pluripotency exit and endodermal differentiation of mouse embryonic stem cells	5
PatternJ: an ImageJ toolset for the automated and quantitative analysis of regular spatial patterns found in sarcomeres, axons, somites, and more	5
Transgenic force sensors and software to measure force transmission across the mammalian nuclear envelope in vivo	5
First person – Ming-Hsuan Wen	5
First person – Ricardo Villalba-Briones	5
trithorax is an essential regulator of cardiac Hox gene expression and anterior-posterior patterning of the Drosophila embryonic heart tube	5
Elliptical Fourier analysis of hominoid radius shape: implications for Ardipithecus ramidus	4
First person – Daniel Lenthall	4
Population-level antagonism between FGF and BMP signaling steers mesoderm differentiation in embryonic stem cells	4
A human stem cell resource to decipher the biochemical and cellular basis of neurodevelopmental defects in Lowe syndrome	4
Beyond bold versus shy: Zebrafish exploratory behavior falls into several behavioral clusters and is influenced by strain and sex	4
PTP10D-mediated cell competition is not obligately required for elimination of polarity-deficient clones	4
First person – Yixing Wu and Ying Bai	4
Visual acuity of budgerigars for moving targets	4
First person – Valentina Laverde	4
Altered epithelial development of the lateral ventricle choroid plexus in Mllt11 mutants	4

Correction: Polyphyllin II inhibits liver cancer cell proliferation, migration and invasion through downregulated cofilin activity and the AKT/NF-κB pathway	4
So long, and thanks for all the papers about fish (and other organisms too)	4
Research culture: science from bench to society	4
midline represses Dpp signaling and target gene expression in Drosophila ventral leg development	4
Dirichlet process mixture models for single-cell RNA-seq clustering	4
Theoretical model of impact mitigation mechanisms inherent to the North American bison skull	4
Correction: IRS-1 increases TAZ expression and promotes osteogenic differentiation in rat bone marrow mesenchymal stem cells	4
Development of the dictyostelid Polysphondylium violaceum does not require secreted cAMP	4
First person – Fatima Batool	4
A genome-wide CRISPR screen implicates plasma membrane asymmetry in exogenous C6-ceramide toxicity	4
EphA1 receptor tyrosine kinase is localized to the nucleus in rhabdomyosarcoma from multiple species	4
The next stage in Biology Open's support for early-career researchers	4
First person – Matthew Penaso-Stinson and Summer Paulson	4
Hepatic leukemia factor-expressing paraxial mesoderm cells contribute to the developing brain vasculature	4
The lymphatic system favours survival of a unique T. brucei population	4
First person – Neydiana Pina-Lopes	4
First person – Alexandra Venuto	4
A larval zebrafish model of cardiac physiological recovery following cardiac arrest and myocardial hypoxic damage	4
Characterization of nitric oxide in Octopus maya nervous system and its potential role in sensory perception	4
Metabolic FRET sensors in intact organs: Applying spectral unmixing to acquire reliable signals	4
Low colostrum intake results in potential accumulation of peroxisome lipid substrates in vaginal tissue of 3-week-old gilts	4
Establishment of a novel protocol for formalin-fixed paraffin-embedded organoids and spheroids	3
Reflections on the EMBO Workshop: Neuroscience of Sleep 2025	3
Connexin 43 mediated collective cell migration is independent of Golgi orientation	3
Human in vivo medial gastrocnemius gear during active and passive muscle lengthening: effect of inconsistent methods and nomenclature on data interpretation	3
First person – Mai Nguyen	3
Ecology, ethology, and evolution in the Anthropocene	3
insideOutside: an accessible algorithm for classifying interior and exterior points, with applications in embryology	3
Hands-on training in structural biology, a tool for sustainable development in Africa series 4	3
Computational tools for quantifying actin filament numbers, lengths, and bundling	3
Flavonols do not affect aphid load in green or senescing birch leaves but coincide with a decrease in Photosystem II functionality	3
Muscle forces and the demands of turning while walking	3
The uncoating of EV71 in mature late endosomes requires CD-M6PR	3
Dynein-2–driven intraciliary retrograde trafficking indirectly requires multiple interactions of IFT54 in the IFT-B complex with the dynein-2 complex	3
Biology Open 2023 – a year in review	3
Mutations in Drosophila tRNA processing factors cause phenotypes similar to Pontocerebellar Hypoplasia	3
The factory, the antenna and the scaffold: the three-way interplay between the Golgi, cilium and extracellular matrix underlying tissue function	3
In vitro forestomach digestion experiments give less-biased estimates of food composition in odontocetes	3
2024 Argentine Group for Extracellular Vesicles (GAVE) Workshop: promoting science in challenging times	3
Redundant functions of the SLC5A transporters Rumpel, Bumpel, and Kumpel in ensheathing glial cells	3
Ecophysiology of neotropical amphibians and reptiles: lessons learned from Colombia	3
Bioengineering of a tumour-stroma 3D-tumouroid co-culture model of hypopharyngeal cancer	3
Targeted mass spectrometry for monitoring of neural differentiation	3
Context-dependent thermolability of sex determination in a lacertid lizard with heteromorphic sex chromosomes	3
Instantaneous visual genotyping and facile site-specific transgenesis via CRISPR-Cas9 and phiC31 integrase	3
Imp and Chinmo are required for embryonic motor neuron axon and dendrite targeting	3
Future leader to watch – Nathan Harmston	3
Hansenula polymorpha cells lacking the ER-localized peroxins Pex23 or Pex29 show defects in mitochondrial function and morphology	3
Analysis of the chromatin landscape and RNA polymerase II binding at SIN3-regulated genes	3
Zebrafish models of alx-linked frontonasal dysplasia reveal a role for Alx1 and Alx3 in the anterior segment and vasculature of the developing eye	3
Neurophysiological measurements of planarian brain activity: a unique model for neuroscience research	3
First person – Martha S. C. Xelhuantzi	3
Developmental disorders caused by haploinsufficiency of transcriptional regulators: a perspective based on cell fate determination	3
First person – Sophie Kraunsoe	3
Automated counting of Drosophila imaginal disc cell nuclei	3
Alveolar epithelial paxillin in postnatal lung alveolar development	3
Germline competent mesoderm: the substrate for vertebrate germline and somatic stem cells?	3
First person – Bailey Calder	3
Re-assessment of the subcellular localization of Bazooka/Par-3 in Drosophila: no evidence for localization to the nucleus and the neuromuscular junction	3
Characterization of gene cluster heterogeneity in single-cell transcriptomic data within and across cancer types	3
First person – Andreas Enström	3
Identification of a postnatal period of interdependent neurogenesis and apoptosis in peripheral neurons	3
Meeting Review of the ‘1st Azerbaijan Neuroscience School: Introduction’	3
First person – Viju Vijayan Pillai and Prasanthi Koganti	3
Allorecognition behaviors in Myxomycetes respond to intraspecies factors	3
CD133/Prom1 marks proximal mouse oviduct epithelial progenitors and adult epithelial cells with a low generative capacity	3
Spatial structure could explain the maintenance of alternative reproductive tactics in tree cricket males	3
New horizons of microphysiological systems: India forging its path in human-relevant research	3
Kinetics of Arf1 inactivation regulates Golgi organisation and function in non-adherent fibroblasts	3
foxg1a is required for hair cell development and regeneration in the zebrafish lateral line	3
SPS1 deficiency-triggered PGRP-LC and Toll expression controls innate immunity in Drosophila S2 cells	3
Constructing a doxycycline-inducible system for an epithelial-to-mesenchymal transition model in MCF10A cells	3
HepT1-derived murine models of high-risk hepatoblastoma display vascular invasion, metastasis, and circulating tumor cells	3
Discontinuous, biphasic, ontogenetic shifts in the metabolic allometry of aquatic animals?	3
Inherited anoxia tolerance and growth performance can result in enhanced invasiveness in hybrid fish	3
First person – Meg Watt	3
Minimal functional domains of the core polarity regulator Dlg	3
Caspar modulates primordial germ cell fate both in an Oskar-dependent and Oskar-independent manner	2
Potentiating Vγ9Vδ2 T cell proliferation and assessing their cytotoxicity towards adherent cancer cells at the single cell level	2
The influence of carbon dioxide on cerebral metabolism and oxygen consumption: combining multimodal monitoring with dynamic systems modelling	2
First person – Justin Varholick	2
Focal sources of FGF-10 promote the buckling morphogenesis of the embryonic airway epithelium	2
First person – Ashley Gendreau	2
First person – Georgia Cullen	2
Multiomics analysis of GSTP1 knockdown pancreatic cancer cells reveals key regulators of redox and metabolic homeostasis	2
Novel protocol to observe the intestinal tuft cell using transmission electron microscopy	2
The story of Biology Open: a conversation with past and present Editors-in-Chief	2
Drosophila CRISPR/Cas9 mutants as tools to analyse cardiac filamin function and pathogenicity of human FLNC variants	2
Expression of Concern: MicroRNA-96-5p promotes proliferation, invasion and EMT of oral carcinoma cells by directly targeting FOXF2	2
First person – Gonzalo Quiroga-Artigas	2
Sexual dimorphism and the impact of aging on ball rolling-associated locomotor behavior in Drosophila	2
An ode to multidisciplinarity: the ‘Bacteria Orchestrate Life’ international meeting	2
First person – Jonathon McPhetres	2
NEDD1-S411 phosphorylation plays a critical function in the coordination of microtubule nucleation during mitosis	2
Ac/Ds transposition for CRISPR/dCas9-SID4x epigenome modulation in zebrafish	2