Biology Open

Article	Citations
First person – Daisy Pineda-Suazo	37
Primary human neutrophils and monocytes migrate along endothelial cell boundaries to optimize search efficiency under static in vitro conditions	34
Unpredictable aggressive defence of the venomous snake, Crotalus ravus, towards predators and humans	31
First person – Rajeshwari B. R.	29
Concrete consequences: construction on prime honey bee habitat doubles foraging distances	27
Reorganization of the heterochromatin-associated gene-dense subcompartment in early neuronal development	24
Cuticular microstructure of the locust femur–tibia joint	24
Local differences in robustness to ocean acidification	24
Over-expressing NadA quinolinate synthase inEscherichia colienhances the bioelectrochemistry in microbial fuel cells	24
Divalent metal content in diet affects severity of manganese toxicity in Drosophila	23
Chromosomal organization of multigene families and meiotic analysis in species of Loricariidae (Siluriformes) from Brazilian Amazon, with description of a new cytotype for genus Spatuloricaria	22
Hip stabilization in an australopithecine-like hip: the influence of shape on muscle activation	20
EyeHex toolbox for complete segmentation of ommatidia in fruit fly eyes	20
The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut	19
Macrophages allocate before apoptosis initiation and produce reactive oxygen species during interdigital phagocytosis	18
Fast & Fair peer review: a bold experiment in scientific publishing	17
Young minds, deeper insights: a recap of the BMAS Summer School 2023, ranging from basic research to clinical implications of bone marrow adipose tissue	16
Knee position affects medial gastrocnemius and soleus activation during dynamic plantarflexion: no evidence for an inter-muscle compensation in healthy young adults	16
Correction: Stable atrogin-1 (Fbxo32) and MuRF1 (Trim63) gene expression is involved in the protective mechanism in soleus muscle of hibernating Daurian ground squirrels (<	16
A year at the forefront of plasmodesmal biology	16
First person – Neha Jadhav Giridhar and Bita Hambrecht	16
shRNAs targeting mouseAdam10diminish cell response to proinflammatory stimuli independently ofAdam10silencing	15
Non-seed plant research in the spotlight	15
Retraction: Overexpression of long non-coding RNA SBF2-AS1 promotes cell progression in esophageal squamous cell carcinoma (ESCC) by repressing miR-494 to up-regulate PFN2 expression	14
Empowering tomorrow's leaders: the impact of the 15th Network of Young Researchers in Andrology (NYRA) meeting on male reproductive health and interdisciplinary collaboration	14

NANOS3 suppresses premature spermatogonial differentiation to expand progenitors and fine-tunes spermatogenesis in mice	14
Shaping the future of male reproductive health: fostering talent at the 14th Network of Young Researchers in Andrology meeting	14
Manipulating mitochondrial reactive oxygen species alters survival in unexpected ways in a Drosophila Cdk5 model of neurodegeneration	13
First person – Franziska Hacker	13
The relationship between locomotion and hindlimb morphology in the leopard (Panthera pardus) using a geometric morphometric approach	13
Ccn2a acts downstream of cx43 to influence joint formation during zebrafish fin regeneration	12
Insulated piggyBac and FRT vectors for engineering transgenic homozygous and heterozygous eHAP cells	12
First person – Mikaela Scheer	12
An experimental test of chronic traffic noise exposure on parental behaviour and reproduction in zebra finches	11
EFEMP1 contributes to light-dependent ocular growth in zebrafish	11
Fluorescent protein tags for human tropomyosin isoform comparison	11
The importance of considering regulatory domains in genome-wide analyses – the nearest gene is often wrong!	11
First person – Avik Banerjee	11
The Endosomal Sorting Complex, ESCRT, has diverse roles in blood progenitor maintenance, lineage choice and immune response	11
First person – Marinus Thein	10
Differential effect of ubiquitous and germline depletion of Integrator complex function on C. elegans physiology	10
Normotensive metabolic syndrome in Transient Receptor Potential Canonical Channel type 1 Trpc1−/− mice.	10
First person – Tom Carruthers	10
Effects of blood extraction and ecophysiological experiments on stress in adult males of Liolaemus attenboroughi	10
First person – Leah Eller	10
Winging it: hummingbirds alter flying kinematics during molt	10
First person – Avery Hinks	10
Social interactions among ants are impacted by food availability and group size	10
Investigating the link between morphological characteristics and diet in an island population of omnivorous reptiles (Sphenodon punctatus)	10
Fully automated point spread function analysis using PyCalibrate	9
Metabolic shift towards oxidative phosphorylation reduces cell-density-induced cancer-stem-cell-like characteristics in prostate cancer in vitro	9
First person – Angela Fan and Yoldas Yildiz	9
Ethanol downregulates gastrula gene expression and cell movement, causing symptoms of foetal alcohol spectrum disorders	9
The Abl-interactor Abi suppresses the function of the BRAG2 GEF family member Schizo	9
From fossils to future – Jane Francis on polar exploration and changing climates	9
Feeding a rich diet supplemented with the translation inhibitor cycloheximide decreases lifespan and ovary size in Drosophila	9
Parental exposure to ocean acidification impacts gamete production and physiology but not offspring performance in Nematostella vectensis	9
Elucidating the genetic architecture of migratory timing in a songbird migrant, the great reed warbler, Acrocephalus arundinaceus	9
Hotter deserts and the impending challenges for the spiny-tailed Lizard in India	8
First person – Isabelle Toussaint-Lardé	8
Investigating the effect of cholinergic and adrenergic blocking agents on maternal-fetal heart rates and their interactions in mice fetuses	8
Meeting proceedings of the 43rd Indian Association for Cancer Research (IACR)	8
Na,K-ATPase activity promotes macropinocytosis in colon cancer via Wnt signaling	8
Retrograde signaling is required for Slm35-mediated negative regulation of mitophagy in yeast	8
Neural crest development and disorders: from patient to model system and back again – the NEUcrest conference	8
Response to Correspondence: Hajnal et al. ‘The role of lin-12 notch in C. elegans anchor cell proliferation’	8
Zika virus-induces metabolic alterations in fetal neuronal progenitors that could influence in neurodevelopment during early pregnancy	8
Holding time has limited impact on constitutive innate immune function in a long-lived Antarctic seabird, the Adélie penguin: implications for field studies	8
Bees display limited acclimation capacity for heat tolerance	8
Frequency-dependent avoidance movement of glass catfish in response to sinusoidal electrical stimulation and associated spiking patterns of electroreceptors	8
Mutational cooperativity of RUNX1::RUNX1T1 isoform 9a and oncogenic NRAS in zebrafish myeloid leukaemia	8
Intrinsic function of the peptidylarginine deiminase PADI4 is dispensable for normal haematopoiesis	8
First person – Latasha Ludwig	7
First person – Kaisa Pakari	7
Gait speed and incline modulate peak deceleration and timing of horizontal center of mass deceleration during double support	7

Metabolic scaling of fire ants ( Solenopsis invicta ) engaged in collective behaviors	7
Reliable replicative lifespan determination of yeast with a single-channel microfluidic chip	7
Hormonal regulation of miRNA during mammary gland development	7
Glycogen synthase is required for heat shock-mediated autophagy induction in neuronal cells	7
The zebrafish ETS transcription factor Fli1b functions upstream of Scl/Tal1 during embryonic hematopoiesis	7
Single-motor and multi-motor motility properties of kinesin-6 family members	7
A novel technique for atraumatic transurethral catheterisation of male rats	7
Morphlight theory inspired by raptors: musculoskeletal modeling and muscle control in Falco peregrinus wing flapping	7
Changes in mitochondrial distribution occur at the axon initial segment in association with neurodegeneration in Drosophila	7
Effects of vessel noise on beluga (Delphinapterus leucas) call type use: ultrasonic communication as an adaptation to noisy environments?	7
ASCL2 is a key regulator of the proliferation–differentiation equilibrium in the esophageal epithelium	7
SlicerMorph photogrammetry: an open-source photogrammetry workflow for reconstructing 3D models	7
Protein complexes from mouse and chick brain that interact with phospho-KXGS motif tau/microtubule associated protein antibody	7
Pacsin2 is required for endocytosis in the zebrafish pronephric tubule	7
Temporal integration and decision-making in crocodiles	7
Insights into Octopus maya cathepsins from metatranscriptome and genome: structure evolutionary relationships and functional role prediction in digestive processes	7
Computational anatomy and geometric shape analysis enables analysis of complex craniofacial phenotypes in zebrafish	7
Vestigial-dependent induction contributes to robust patterning but is not essential for wing-fate recruitment in Drosophila	7
Aging disrupts spatiotemporal regulation of germline stem cells and niche integrity	7
Euglena International Network (EIN): Driving euglenoid biotechnology for the benefit of a challenged world	7
Retraction: Overexpression of Wnt7a enhances radiosensitivity of non-small-cell lung cancer via the Wnt/JNK pathway	7
Linking peak intensity of mechanically stimulated bioluminescence and cell surface area in dinoflagellates	7
First person – Francesca Mastropasqua and Marika Oksanen	6
A Drosophila model of mitochondrial disease phenotypic heterogeneity	6
First person – Adam Downie	6
Actin cytoskeleton in angiogenesis	6
Increased expression of the small lysosomal gene SVIP in the Drosophila gut suppresses pathophysiological features associated with a high-fat diet	6
First person – Emily Bulger	6
The placental effects of trisomy for human chromosome 21 orthologs in four mouse models of Down syndrome	6
Innervation of the developing kidney in vivo and in vitro	6
Retraction: MicroRNA-96-5p promotes proliferation, invasion and EMT of oral carcinoma cells by directly targeting FOXF2	6
The Company of Biologists: a century in review	6
First person – Kelly Diamond	6
Maintenance of neuronal fate and transcriptional identity	6
Intermittent hypoxia differentially affects metabolic and oxidative stress responses in two species of cyprinid fish	6
Cerebral organoids in primary progressive multiple sclerosis reveal stem cell and oligodendrocyte differentiation defect	6
Biomechanical analysis of little penguins’ underwater locomotion from the free-ranging dive data	6
Coilin as a regulator of NF-kB mediated inflammation in preeclampsia	6
Partial role of volatile organic compounds in behavioural responses of mice to bedding from cancer-affected congeners	6
CDX2 dose-dependently influences the gene regulatory network underlying human extraembryonic mesoderm development	6
An optimized retroviral toolbox for overexpression and genetic perturbation of primary lymphocytes	6
Alterations in lifespan and sleep:wake duration under selective monochromes of visible light in Drosophila melanogaster	6
Ethanol induces subcellular trafficking of the RNA-binding protein, hnRNP A1, in neuronal cells in vitro, but not in the peripubertal rat brain	6
Reevaluating the relationship between EGL-43 (EVI1) and LIN-12 (Notch) during C. elegans anchor cell invasion	6
Deletion of taf1 and taf5 in zebrafish capitulate cardiac and craniofacial abnormalities associated with TAFopathies through perturbations in metabolism	6
Experimental playback of urban noise does not affect cognitive performance in captive Australian magpies	6
microRNA-guided immunity against respiratory virus infection in human and mouse lung cells	6
Antimicrobial peptide expression in the cockroach gut during enterobacterial infection is specific and influenced by type III secretion	6
SOX2 and NR2F1 coordinate the gene expression program of the early postnatal visual thalamus	6
Wnt and BMP signalling direct anterior–posterior differentiation in aggregates of mouse embryonic stem cells	6
Characterization of alternative splicing during mammalian brain development reveals the extent of isoform diversity and potential effects on protein structural changes	6
Saccharomyces cerevisiae deficient in the early anaphase release of Cdc14 can traverse anaphase I without ribosomal DNA disjunction and successfully complete meiosis	5
First person – Amy Irving	5
First person – Ricardo Villalba-Briones	5
First person – Neydiana Pina-Lopes	5
First person – Ming-Hsuan Wen	5
Gene expression and DNA methylation changes in response to hypoxia in toxicant-adapted Atlantic killifish ( Fundulus heteroclitus )	5
Alpha-T-catenin is expressed in peripheral nerves as a constituent of Schwann cell adherens junctions	5
Plpp3, a novel regulator of pluripotency exit and endodermal differentiation of mouse embryonic stem cells	5
Transgenic force sensors and software to measure force transmission across the mammalian nuclear envelope in vivo	5
IFT139 regulates Hedgehog signaling and cilia structure through ciliary protein localization	5
Correction: IRS-1 increases TAZ expression and promotes osteogenic differentiation in rat bone marrow mesenchymal stem cells	5
trithorax is an essential regulator of cardiac Hox gene expression and anterior-posterior patterning of the Drosophila embryonic heart tube	5
Introducing Daniel Gorelick – a new Editor-in-Chief for Biology Open	5
Cdc48 and its co-factor Ufd1 extract CENP-A from centromeric chromatin and can induce chromosome elimination in the fission yeast Schizosaccharomyces pombe	5
exTREEmaTIME: a method for incorporating uncertainty into divergence time estimates	5
PatternJ: an ImageJ toolset for the automated and quantitative analysis of regular spatial patterns found in sarcomeres, axons, somites, and more	5
Zebrafish embryos hatch early in response to chemical and mechanical indicators of predation risk, resulting in underdeveloped swimming ability of hatchling larvae	5
A human stem cell resource to decipher the biochemical and cellular basis of neurodevelopmental defects in Lowe syndrome	5
Theoretical model of impact mitigation mechanisms inherent to the North American bison skull	5
First person – Daniel Lenthall	5
midline represses Dpp signaling and target gene expression in Drosophila ventral leg development	5
Sox8: a multifaceted transcription factor in development and disease	5
Experimental short-term heatwaves negatively impact body weight gain and survival during larval development in Bombus terrestris L. (Hymenoptera: Apidae)	5
Stress-induced elemental retention in an ectothermic vertebrate	5
Beyond bold versus shy: Zebrafish exploratory behavior falls into several behavioral clusters and is influenced by strain and sex	4
First person – Alexandra Venuto	4
First person – Meg Watt	4
The uncoating of EV71 in mature late endosomes requires CD-M6PR	4
WntA expression and wing transcriptomics illuminate the evolution of stripe patterns in skipper butterflies	4

First person – Matthew Penaso-Stinson and Summer Paulson	4
Correction: Polyphyllin II inhibits liver cancer cell proliferation, migration and invasion through downregulated cofilin activity and the AKT/NF-κB pathway	4
Future leader to watch – Nathan Harmston	4
So long, and thanks for all the papers about fish (and other organisms too)	4
The next stage in Biology Open's support for early-career researchers	4
Spatial structure could explain the maintenance of alternative reproductive tactics in tree cricket males	4
BBQ methods: streamlined workflows for bacterial burden quantification in infected cells by confocal microscopy	4
Dirichlet process mixture models for single-cell RNA-seq clustering	4
Tbx5 overexpression in embryoid bodies increases TAK1 expression but does not enhance the differentiation of sinoatrial node cardiomyocytes	4
Hepatic leukemia factor-expressing paraxial mesoderm cells contribute to the developing brain vasculature	4
First person – Mai Nguyen	4
Discontinuous, biphasic, ontogenetic shifts in the metabolic allometry of aquatic animals?	4
foxg1a is required for hair cell development and regeneration in the zebrafish lateral line	4
A genome-wide CRISPR screen implicates plasma membrane asymmetry in exogenous C6-ceramide toxicity	4
First person – Fatima Batool	4
Development of the dictyostelid Polysphondylium violaceum does not require secreted cAMP	4
First person – Valentina Laverde	4
Altered epithelial development of the lateral ventricle choroid plexus in Mllt11 mutants	4
PTP10D-mediated cell competition is not obligately required for elimination of polarity-deficient clones	4
Low colostrum intake results in potential accumulation of peroxisome lipid substrates in vaginal tissue of 3-week-old gilts	4
The lymphatic system favours survival of a unique T. brucei population	4
Cohesin protein Smc3 influences kinocilial structure and function	4
Population-level antagonism between FGF and BMP signaling steers mesoderm differentiation in embryonic stem cells	4
Flavonols do not affect aphid load in green or senescing birch leaves but coincide with a decrease in Photosystem II functionality	4
A pro-angiogenic and hypoxic zebrafish model as a novel platform for anti-angiogenic drug testing	4
Temporal transcriptomic profiling of human three-dimensional neuromuscular co-cultures	4
Elliptical Fourier analysis of hominoid radius shape: implications for Ardipithecus ramidus	4
Characterization of nitric oxide in Octopus maya nervous system and its potential role in sensory perception	4
EphA1 receptor tyrosine kinase is localized to the nucleus in rhabdomyosarcoma from multiple species	4
Metabolic FRET sensors in intact organs: Applying spectral unmixing to acquire reliable signals	4
PIWIL2 downregulation in colon cancer promotes transposon activity and pro-tumorigenic phenotypes	4
A larval zebrafish model of cardiac physiological recovery following cardiac arrest and myocardial hypoxic damage	4
Expression levels and activities of energy-yielding ATPases in the oligohaline neritid snail Theodoxus fluviatilis under changing environmental salinities	4
Development of a cypovirus protein microcrystal-encapsulated Bacillus thuringiensis UV-tolerant and mosquitocidal δ-endotoxin	4
Hansenula polymorpha cells lacking the ER-localized peroxins Pex23 or Pex29 show defects in mitochondrial function and morphology	3
Inherited anoxia tolerance and growth performance can result in enhanced invasiveness in hybrid fish	3
Establishment of a novel protocol for formalin-fixed paraffin-embedded organoids and spheroids	3
Ammonia transport mediated by urea transporter A isoforms	3
insideOutside: an accessible algorithm for classifying interior and exterior points, with applications in embryology	3
Muscle forces and the demands of turning while walking	3
2024 Argentine Group for Extracellular Vesicles (GAVE) Workshop: promoting science in challenging times	3
HepT1-derived murine models of high-risk hepatoblastoma display vascular invasion, metastasis, and circulating tumor cells	3
Biology Open 2023 – a year in review	3
Characterization of gene cluster heterogeneity in single-cell transcriptomic data within and across cancer types	3
Meeting Review of the ‘1st Azerbaijan Neuroscience School: Introduction’	3
First person – Sophie Kraunsoe	3
Constructing a doxycycline-inducible system for an epithelial-to-mesenchymal transition model in MCF10A cells	3
Mass loss, timing and duration of catastrophic moult in little penguins	3
Human in vivo medial gastrocnemius gear during active and passive muscle lengthening: effect of inconsistent methods and nomenclature on data interpretation	3
Identification of a postnatal period of interdependent neurogenesis and apoptosis in peripheral neurons	3
A high-resolution bovine mitochondrial co-expression network	3
New horizons of microphysiological systems: India forging its path in human-relevant research	3
Early-life challenge enhances cortisol regulation in zebrafish larvae	3
Context-dependent thermolability of sex determination in a lacertid lizard with heteromorphic sex chromosomes	3
SPS1 deficiency-triggered PGRP-LC and Toll expression controls innate immunity in Drosophila S2 cells	3
Generation of mice with combined Hexa Gly269Ser KI or KO and Neu3 KO alleles to create new models of GM2 gangliosidoses	3
In vitro forestomach digestion experiments give less-biased estimates of food composition in odontocetes	3
Connexin 43 mediated collective cell migration is independent of Golgi orientation	3
Flat mount preparation for whole-mount fluorescent imaging of zebrafish embryos	3
Allorecognition behaviors in Myxomycetes respond to intraspecies factors	3
The factory, the antenna and the scaffold: the three-way interplay between the Golgi, cilium and extracellular matrix underlying tissue function	3
Instantaneous visual genotyping and facile site-specific transgenesis via CRISPR-Cas9 and phiC31 integrase	3
Differential effects of Mendelian GDAP1 clinical variants on mitochondria-lysosome membrane contacts sites	3
Ecophysiology of neotropical amphibians and reptiles: lessons learned from Colombia	3
Reflections on the EMBO Workshop: Neuroscience of Sleep 2025	3
Neurotranscriptomic profiling of deformed wing virus-infected honey bee foragers ( Apis mellifera ) with different cognitive abilities	3
First person – Martha S. C. Xelhuantzi	3
Advancing developmental biology in Central Europe: report from the V4SDB meeting 2025	3
CD133/Prom1 marks proximal mouse oviduct epithelial progenitors and adult epithelial cells with a low generative capacity	3
Dynein-2–driven intraciliary retrograde trafficking indirectly requires multiple interactions of IFT54 in the IFT-B complex with the dynein-2 complex	3
Hands-on training in structural biology, a tool for sustainable development in Africa series 4	3
Ecology, ethology, and evolution in the Anthropocene	3
Kinetics of Arf1 inactivation regulates Golgi organisation and function in non-adherent fibroblasts	3
Redundant functions of the SLC5A transporters Rumpel, Bumpel, and Kumpel in ensheathing glial cells	3
Imp and Chinmo are required for embryonic motor neuron axon and dendrite targeting	3
Alveolar epithelial paxillin in postnatal lung alveolar development	3
Developmental disorders caused by haploinsufficiency of transcriptional regulators: a perspective based on cell fate determination	3
First person – Bailey Calder	3
miR-302 regulates pancreatic progenitor pool and pancreatic size	3
First person – Sarit Pal	3
Analysis of the chromatin landscape and RNA polymerase II binding at SIN3-regulated genes	3
Automated counting of Drosophila imaginal disc cell nuclei	3
Neurophysiological measurements of planarian brain activity: a unique model for neuroscience research	3
Metabolic stress and muscle mechanics: Acute response of isolated soleus and EDL muscles to prolonged fasting in mice with distinct muscle phenotypes	3
First person – Andreas Enström	3
First person – Santu Saha	3
Re-assessment of the subcellular localization of Bazooka/Par-3 in Drosophila: no evidence for localization to the nucleus and the neuromuscular junction	3
Zebrafish model reveals developmental and hematopoietic functions of ADAMTS13	3
P2X7 regulates ependymo-radial glial cell proliferation in adult Danio rerio following spinal cord injury	3
Bioengineering of a tumour-stroma 3D-tumouroid co-culture model of hypopharyngeal cancer	3
Generation and characterization of a knockout mouse of an enhancer of EBF3	3
Computational tools for quantifying actin filament numbers, lengths, and bundling	3
Minimal functional domains of the core polarity regulator Dlg	3
Zebrafish models of alx-linked frontonasal dysplasia reveal a role for Alx1 and Alx3 in the anterior segment and vasculature of the developing eye	3
Mutations in Drosophila tRNA processing factors cause phenotypes similar to Pontocerebellar Hypoplasia	3