Biology Open

Article	Citations
Cardiac myosin super relaxation (SRX): a perspective on fundamental biology, human disease and therapeutics	51
Reissner fibre-induced urotensin signalling from cerebrospinal fluid-contacting neurons prevents scoliosis of the vertebrate spine	40
Molecular mechanisms of neurodegeneration in the entorhinal cortex that underlie its selective vulnerability during the pathogenesis of Alzheimer's disease	38
BMP-treated human embryonic stem cells transcriptionally resemble amnion cells in the monkey embryo	32
Specificity and off-target effects of AAV8-TBG viral vectors for the manipulation of hepatocellular gene expression in mice	27
Efficient and crucial quality control of HAP1 cell ploidy status	25
Quantified growth of the human embryonic heart	25
Uncharted routes: exploring the relevance of auxin movement via plasmodesmata	22
A versatile, automated and high-throughput drug screening platform for zebrafish embryos	20
Publishing ethics in the era of paper mills	19
Three-dimensional model of glioblastoma by co-culturing tumor stem cells with human brain organoids	18
RNA-Seq reveals changes in human placental metabolism, transport and endocrinology across the first–second trimester transition	17
Recent developments of tools for genome and metabolome studies in basidiomycete fungi and their application to natural product research	16
Genome wide association study for the identification of genes associated with tail fat deposition in Chinese sheep breeds	16
Developmental disorders caused by haploinsufficiency of transcriptional regulators: a perspective based on cell fate determination	15
Local adaptation in thermal tolerance for a tropical butterfly across ecotone and rainforest habitats	15
ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane	14
Redundant functions of the SLC5A transporters Rumpel, Bumpel, and Kumpel in ensheathing glial cells	14
Motion: enhancing signals and concealing cues	14
20-hydroxyecdysone (20E) signaling regulates amnioserosa morphogenesis during Drosophila dorsal closure: EcR modulates gene expression in a complex with the AP-1 subunit, Jun	13
Auxin confers protection against ER stress in Caenorhabditis elegans	13
The SARS-CoV-2 receptor and other key components of the Renin-Angiotensin-Aldosterone System related to COVID-19 are expressed in enterocytes in larval zebrafish	13
Altered germline cyst formation and oogenesis in Tex14 mutant mice	13
Dynamic neurotransmitter specific transcription factor expression profiles during Drosophila development	12
The LRRK2 signaling network converges on a centriolar phospho-Rab10/RILPL1 complex to cause deficits in centrosome cohesion and cell polarization	12

Bisphenol A promotes stress granule assembly and modulates the integrated stress response	12
A Caenorhabditis elegans behavioral assay distinguishes early stage prostate cancer patient urine from controls	12
Shifting away from the business-as-usual approach to research conferences	12
Mechanical and energetic determinants of impaired gait following stroke: segmental work and pendular energy transduction during treadmill walking	12
Efficient induction and sustenance of pluripotent stem cells from bovine somatic cells	11
Specificity, redundancy and dosage thresholds among gata4/5/6 genes during zebrafish cardiogenesis	11
Stability of amino acids and related amines in human serum under different preprocessing and pre-storage conditions based on iTRAQ®-LC-MS/MS	11
Palmitoylated small GTPase ARL15 is translocated within Golgi network during adipogenesis	11
CD47 differentially regulates white and brown fat function	11
Neural crest cells require Meis2 for patterning the mandibular arch via the Sonic hedgehog pathway	11
Beyond bold versus shy: Zebrafish exploratory behavior falls into several behavioral clusters and is influenced by strain and sex	11
Gap junctions: historical discoveries and new findings in the C aenorhabditis  elegans nervous system	11
Conditional targeting of phosphatidylserine decarboxylase to lipid droplets	10
Auxin treatment increases lifespan in Caenorhabditis elegans	10
KDM5A and KDM5B histone-demethylases contribute to HU-induced replication stress response and tolerance	9
Euglena International Network (EIN): Driving euglenoid biotechnology for the benefit of a challenged world	9
Convergent acoustic community structure in South Asian dry and wet grassland birds	9
Quantitative analysis of signaling responses during mouse primordial germ cell specification	9
Computational anatomy and geometric shape analysis enables analysis of complex craniofacial phenotypes in zebrafish	9
Sleep-length differences are associated with altered longevity in the fruit fly Drosophila melanogaster	9
Connecting different heart diseases through intercellular communication	9
Eye morphogenesis in the blind Mexican cavefish	9
Compartment and cell-type specific hypoxia responses in the developing Drosophila brain	9
Presynaptic HCN channels constrain GABAergic synaptic transmission in pyramidal cells of the medial prefrontal cortex	9
High glucose induces Nox4 expression and podocyte apoptosis through the Smad3/ezrin/PKA pathway	8
A glucose-supplemented diet enhances gut barrier integrity in Drosophila	8
The Drosophila orthologue of the primary ciliary dyskinesia-associated gene, DNAAF3, is required for axonemal dynein assembly	8
Muscle forces and the demands of human walking	8
Myotonic dystrophy type 1 embryonic stem cells show decreased myogenic potential, increased CpG methylation at the DMPK locus and RNA mis-splicing	8
Synovial joint cavitation initiates with microcavities in interzone and is coupled to skeletal flexion and elongation in developing mouse embryo limbs	8
Basement membrane dynamics and mechanics in tissue morphogenesis	8
Biophysical and biochemical properties of Deup1 self-assemblies: a potential driver for deuterosome formation during multiciliogenesis	8
Heart rate and startle responses in diving, captive harbour porpoises (Phocoena phocoena) exposed to transient noise and sonar	7
Perinatal exposure to synergistic multiple stressors leads to cellular and behavioral deficits mimicking Schizophrenia-like pathology	7
Downregulated brain and muscle aryl hydrocarbon receptor nuclear translocator-like protein-1 inhibits osteogenesis of BMSCs through p53 in type 2 diabetes mellitus	7
Apoptosis is a generator of Wnt-dependent regeneration and homeostatic cell renewal in the ascidian Ciona	7
Design of a 3D printed, motorized, uniaxial cell stretcher for microscopic and biochemical analysis of mechanotransduction	7
Validating accelerometry-derived proxies of energy expenditure using the doubly labelled water method in the smallest penguin species	7
Downstream events initiated by expression of FSHD-associated DUX4: Studies of nucleocytoplasmic transport, γH2AX accumulation, and Bax/Bak-dependence	7
Transduction of rat and human adipose-tissue derived mesenchymal stromal cells by adeno-associated viral vector serotype DJ	7
Influence of weighted downhill running training on serial sarcomere number and work loop performance in the rat soleus	7
Requirement for STAT3 and its target, TFCP2L1, in self-renewal of naïve pluripotent stem cells in vivo and in vitro	7
Src family kinases inhibit differentiation of intestinal epithelial cells through the Hippo effector YAP1	7
Pigment pattern morphospace ofDaniofishes: evolutionary diversification and mutational effects	7
RGS5: a novel role as a hypoxia-responsive protein that suppresses chemokinetic and chemotactic migration in brain pericytes	7
The importance of considering regulatory domains in genome-wide analyses – the nearest gene is often wrong!	7
Actin cytoskeleton in angiogenesis	7
Cerebral organoids in primary progressive multiple sclerosis reveal stem cell and oligodendrocyte differentiation defect	7
Postnatal expression profiles of atypical cadherin FAT1 suggest its role in autism	6
Interaction between Discs large and Pins/LGN/GPSM2: a comparison across species	6

A mouse model displays host and bacterial strain differences in Aerococcus urinae urinary tract infection	6
Mutations in the splicing regulator Prp31 lead to retinal degeneration in Drosophila	6
A Year at the Forefront of Engineering Photosynthesis	6
A nematode-derived, mitochondrial stress signaling-regulated peptide exhibits broad antibacterial activity	6
Mummichog gill and operculum exhibit functionally consistent claudin-10 paralog profiles and Claudin-10c hypersaline response	6
MicroRNA-9-5p inhibits proliferation and induces apoptosis of human hypertrophic scar fibroblasts through targeting peroxisome proliferator-activated receptor β	6
A guide to preprinting for early-career researchers	6
Effect of heterogeneous substrate adhesivity of follower cells on speed and tension profile of leader cells in primary keratocyte collective cell migration	6
Alone in a crowd: effect of a nonfunctional lateral line on expression of the social hormone parathyroid hormone 2	6
Fracture biomechanics influence local and systemic immune responses in a murine fracture-related infection model	6
Zebrafish models of alx-linked frontonasal dysplasia reveal a role for Alx1 and Alx3 in the anterior segment and vasculature of the developing eye	6
Responses to transient receptor potential (TRP) channel agonists inChlamydomonas reinhardtii	6
The dorsal blastopore lip is a source of signals inducing planar cell polarity in the Xenopus neural plate	6
Regulation of NANOG and SOX2 expression by activin A and a canonical WNT agonist in bovine embryonic stem cells and blastocysts	6
MonitoringSchizosaccharomyces pombegenome stress by visualizing end-binding protein Ku	6
Tissue-specific transcriptome profiles identify functional differences key to understanding whole plant response to life in variable salinity	6
Lifespan and ROS levels in different Drosophila melanogaster strains after 24 h hypoxia exposure	6
Associative learning in larval and adultDrosophilais impaired by the dopamine-synthesis inhibitor 3-Iodo-L-tyrosine	6
A kinase translocation reporter reveals real-time dynamics of ERK activity in Drosophila	6
Modulation of retinoid-X-receptors differentially regulates expression of apolipoprotein genes apoc1 and apoeb by zebrafish microglia	6
The uncoating of EV71 in mature late endosomes requires CD-M6PR	6
Energetics of whiskered bats in comparison to other bats of the family Vespertilionidae	6
Variations in oxidative stress and antioxidant defense level during different phases of hibernation in common Asian toad,Duttaphrynus melanostictus	6
Vitamin D receptor absence does not enhance intestinal tumorigenesis in ApcPirc/+rats	5
Exocrine pancreas proteases regulate β-cell proliferation in zebrafish ciliopathy models and in murine systems	5
Oviductal fluid counterbalances the negative effect of high temperature on sperm in an ectotherm model	5
Developmental expression patterns of toolkit genes in male accessory gland ofDrosophilaparallels those of mammalian prostate	5
Development of a highly pulmonary metastatic orthotopic renal cell carcinoma murine model	5
Soluble receptor for advanced glycation end products protects from ischemia- and reperfusion-induced acute kidney injury	5
Drosophila hemocytes recognize lymph gland tumors of mxc mutants and activate the innate immune pathway in a reactive oxygen species-dependent manner	5
Phenotype assessment for neurodegenerative murine models with ataxia and application to Niemann–Pick disease, type C1	5
Research culture: science from bench to society	5
Serotonin: an overlooked regulator of endocytosis and endosomal sorting?	5
Phospholipids containing ether-bound hydrocarbon-chains are essential for efficient phagocytosis and neutral lipids of the ester-type perturb development in Dictyostelium	5
Three functional polymorphisms in CCDC170 were associated with osteoporosis phenotype	5
Mutations in Drosophila tRNA processing factors cause phenotypes similar to Pontocerebellar Hypoplasia	5
Orally administered branaplam does not impact neurogenesis in juvenile mice, rats, and dogs	5
Antimicrobial peptide expression in the cockroach gut during enterobacterial infection is specific and influenced by type III secretion	5
Smoking flies: testing the effect of tobacco cigarettes on heart function ofDrosophila melanogaster	5
Viral species differentially influence macronutrient preferences based on honey bee genotype	5
EPCAM and TROP2 share a role in claudin stabilization and development of intestinal and extraintestinal epithelia in mice	5
A human stem cell resource to decipher the biochemical and cellular basis of neurodevelopmental defects in Lowe syndrome	5
Patterns of variations in dorsal colouration of the Italian wall lizard Podarcis siculus	5
A fully automated deep learning pipeline for high-throughput colony segmentation and classification	5
Functionally distinct roles for T and Tbx6 during mouse development	5
Influence of maternal diet on offspring survivorship, growth, and reproduction in a sheetweb spider	5
DNMT1 is a negative regulator of osteogenesis	5
Light-sheet microscopy reveals dorsoventral asymmetric membrane dynamics ofAmoeba proteusduring pressure-driven locomotion	4
Mapping the transcriptomic changes of endothelial compartment in human hippocampus across aging and mild cognitive impairment	4
Genetically inducible and reversible zebrafish model of systemic inflammation	4
Overexpression of Wnt7a enhances radiosensitivity of non-small-cell lung cancer via the Wnt/JNK pathway	4
A node-based informed modularity strategy to identify organizational modules in anatomical networks	4
Dissecting dynamics and differences of selective pressures in the evolution of human pigmentation	4
Effects of mechanical stimulation on metabolomic profiles of SW1353 chondrocytes: shear and compression	4
Tight junction stabilization prevents HepaRG cell death in drug-induced intrahepatic cholestasis	4
Integrated analysis of cell shape and movement in moving frame	4
Ctdp1 deficiency leads to early embryonic lethality in mice and defects in cell cycle progression in MEFs	4
A new method to localise and quantify oxidative stress in live juvenile mussels	4
Metabolic scaling of fire ants (Solenopsis invicta) engaged in collective behaviors	4
What drives mixed-species shoaling among wild zebrafish? The roles of predators, food access, abundance of conspecifics and familiarity	4
Investigating the effect of cholinergic and adrenergic blocking agents on maternal-fetal heart rates and their interactions in mice fetuses	4
A Year at the Forefront of Bacterial Defense Systems Against Neutrophilic Oxidants	4
Dorso-ventral heterogeneity in tracheal basal stem cells	4
Modulation of mitochondrial nucleoid structure during aging and by mtDNA content in Drosophila	4
The genomic basis of host and vector specificity in non-pathogenic trypanosomatids	4
RNA-seq analysis and compound screening highlight multiple signalling pathways regulating secondary cell death after acute CNS injuryin vivo	4
Interdomain interactions regulate the localization of a lipid transfer protein at ER-PM contact sites	4
Pressure-induced changes on the morphology and gene expression in mammalian cells	4
Initial parasitic behaviour of the temporary social parasitic ant Polyrhachis lamellidens can be induced by host-like cuticles in laboratory environment	4
Chromatin dynamics through mouse preimplantation development revealed by single molecule localisation microscopy	4
Quantitative evaluation of individual food intake by insectivorous vespertilionid bats (Chiroptera, Vespertilionidae)	4
DJ-1 promotes epithelial-to-mesenchymal transition via enhancing FGF9 expression in colorectal cancer	4
Insights into in vivo adipocyte differentiation through cell-specific labeling in zebrafish	4
Single-cell sequencing reveals the potential oncogenic expression atlas of human iPSC-derived cardiomyocytes	4
The thermal dependence and molecular basis of physiological color change in Takydromus septentrionalis (Lacertidae)	4
Development of a cypovirus protein microcrystal-encapsulated Bacillus thuringiensis UV-tolerant and mosquitocidal δ-endotoxin	4
Dirichlet process mixture models for single-cell RNA-seq clustering	4
Zebrafish embryos hatch early in response to chemical and mechanical indicators of predation risk, resulting in underdeveloped swimming ability of hatchling larvae	4
Arf GTPase-activating proteins SMAP1 and AGFG2 regulate the size of Weibel-Palade bodies and exocytosis of von Willebrand factor	4
Minimal functional domains of the core polarity regulator Dlg	4

Multiple neural bHLHs ensure the precision of a neuronal specification event in Caenorhabditis elegans	4
Coilin as a regulator of NF-kB mediated inflammation in preeclampsia	4
GRASP55 restricts early-stage autophagy and regulates spatial organization of the early secretory network	4