OOIR: Observatory of International Research

Papers

(The median citation count of Clinical & Translational Immunology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
	107
	92
SARS‐CoV‐2‐associated T‐cell infiltration in the central nervous system	52
The spectrum of B cells in the pathogenesis, diagnosis and therapeutic applications of immunoglobulin G4‐related disease	43
Circulating cytokine and chemokine patterns associated with cytomegalovirus reactivation after stem cell transplantation	39
Characteristics of PD‐1⁺CD4⁺ T cells in peripheral blood and synovium of rheumatoid arthritis patients	37
Biomarkers to predict and diagnose pulmonary complications in children post haematopoietic stem cell transplant	36
Polyfunctional T peripheral helper cells are associated with the magnitude and durability of antibody responses after COVID‐19	31
Impact of adaptive natural killer cells, KLRC2 genotype and cytomegalovirus reactivation on late mortality in patients with severe COVID‐19 lung disease	27
An optimised whole blood interleukin‐2 release assay is more sensitive than interferon‐γ ELIS pot for detecting and quantifying gluten‐specific	27
	26
Heterologous booster vaccination with CoronaVac following prime vaccination with mRNA vaccine	25
	25
Effects of extremely preterm birth on cytokine and chemokine responses induced by T‐cell activation during infancy	25
	24
Retrospective analysis of the efficacy of adjuvant cytokine‐induced killer cell immunotherapy combined with chemotherapy in colorectal cancer patients after surgery	24
	23
Targeting BMI‐1 to deplete antibody‐secreting cells in autoimmunity	22
The contribution of the alternative pathway in complement activation on cell surfaces depends on the strength of classical pathway initiation	21
Endogenous bystander killing mechanisms enhance the activity of novel FAP‐specific CAR‐T cells against glioblastoma	21
Adeno‐associated viral vectors encoding anti‐P2X7 nanobodies reduce graft‐versus‐host disease in a humanised mouse model	21
Validation and performance of a multiplex serology assay to quantify antibody responses following SARS‐CoV‐2 infection or vaccination	20
Inhibitory effect of hydroxychloroquine on glucocorticoid‐induced osteoporosis in lupus therapy	19
Optimised modular anti‐FLAG CAR T cells for solid tumor therapy	19
Mass cytometry analysis reveals altered immune profiles in patients with coronary artery disease	19

	19
Siglec‐1, an easy and contributory inflammation marker in rheumatology	18
Genome‐wide association study and polygenic risk scores of eosinophilia in Taiwan	18
Increased mast cell activation in eosinophilic chronic obstructive pulmonary disease	18
Robust immunity to influenza vaccination in haematopoietic stem cell transplant recipients following reconstitution of humoral and adaptive immunity	17
Naturally acquired adaptive immunity to Streptococcus pneumoniae is impaired in rheumatoid arthritis patients	17
	17
	17
	16
High KRT17 expression in tumour budding indicates immunologically ‘hot’ tumour budding and predicts good survival in patients with colorectal cancer	15
Skin immunity and inflammation: cellular interactions and communication	15
Identification of polo‐like kinase 1 as a therapeutic target in murine lupus	15
Identification of distinct immune signatures in inclusion body myositis by peripheral blood immunophenotyping using machine learning models	14
Increased amphiregulin expression by CD4⁺ T cells from individuals with asymptomatic Leishmania donovani infection	14
Immunoregulatory effects of testosterone supplementation combined with exercise training in men with Inclusion Body Myositis: a double‐blind, placebo‐controlled, cross‐over trial	13
Exploring NK cell receptor dynamics in paediatric leukaemias: implications for immunotherapy and prognosis	13
Human axillary lymph node T follicular helper (Tfh) and Precursor‐Tfh cells exhibit functional flexibility following seasonal influenza vaccination	13
A preclinical study of allogeneic CD19 chimeric antigen receptor double‐negative T cells as an off‐the‐shelf immunotherapy drug against B‐cell malignancies	13
Prediction of intravenous immunoglobulin retreatment in children with Kawasaki disease using models combining lymphocyte subset and cytokine profile in an East Asian cohort	13
Data standards for single‐cell RNA‐sequencing of paediatric cancer	13
CD39 expression defines exhausted CD4⁺ T cells associated with poor survival and immune evasion in human gastric cancer	13
	13
	13
A unique cytotoxic CD4 ⁺ T cell‐signature defines critical COVID‐19	12
Epstein–Barr virus infection, B‐cell dysfunction and other risk factors converge in gut‐associated lymphoid tissue to drive the immunopathogenesis of multiple sclerosis: a hypothesis	12
Genome‐wide off‐target analyses of CRISPR/Cas9‐mediated T‐cell receptor engineering in primary human T cells	12
Hypoxia‐inducible factor‐1α regulates the interleukin‐6 production by B cells in rheumatoid arthritis	12
Importance of crosstalk between the microbiota and the neuroimmune system for tissue homeostasis	11
Effect of washed versus unwashed red blood cells on transfusion‐related immune responses in preterm newborns	11
Targeting SARS‐CoV ‐2 infection through CAR‐T ‐like bispecific T cell engagers incorporating	11
Pulmonary complications post allogeneic haematopoietic stem cell transplant in children	11
Adoptive T‐cell therapy targeting Epstein–Barr virus as a treatment for multiple sclerosis	10
Inflammasome activation: from molecular mechanisms to autoinflammation	10
Spatial proteomic profiling of tumor and stromal compartments in non‐small‐cell lung cancer identifies signatures associated with overall survival	9
	9
	9
Administration of an LXR agonist promotes atherosclerotic lesion remodelling in murine inflammatory arthritis	9
Infiltrating characteristics and prognostic value of tertiary lymphoid structures in resected gastric neuroendocrine neoplasm patients	9
Serological responses and clinical outcomes following a three‐dose primary COVID‐19 vaccine schedule in kidney transplant recipients and people on dialysis	9
Long‐term effects of influenza and Bacille Calmette–Guérin vaccination on systemic inflammation	9
Antigen‐specific polyfunctional cytotoxic T cells differentiate intraocular from peripheral blood immune responses in posterior uveitis	8
Multi‐omics integration reveals a nonlinear signature that precedes progression of lung fibrosis	8
Sex‐bias in CD8⁺ T‐cell stemness and exhaustion in cancer	8
Graft CD8 T‐cell‐based risk system predicts survival in antithymocyte globulin‐based myeloablative haploidentical peripheral blood stem cell transplantation	8
Memory stem T cells modified with a redesigned CD30‐chimeric antigen receptor show an enhanced antitumor effect in Hodgkin lymphoma	8
Allogeneic haematopoietic stem cell transplantation resets T‐ and B‐cell compartments in sickle cell disease patients	8
Blood transcriptomics identifies immune signatures indicative of infectious complications in childhood cancer patients with febrile neutropenia	8
Elucidating novel immune profiles for predicting infection in high‐risk cohorts: a pilot study in patients with relapsed and refractory chronic lymphocytic leukaemia	8
Effect of Bacille Calmette–Guérin vaccination on immune responses to SARS‐CoV‐2 and COVID‐19 vaccination	8
Understanding the tumor microenvironment in head and neck squamous cell carcinoma	8

Genetic differences in the HLA region contribute to the variability in SARS‐CoV‐2 vaccine responsiveness of older persons: the Doetinchem Cohort Study	8
High‐dimensional spectral cytometry identifies follicular regulatory CD8 ⁺ T cells in diffuse large B‐cell lymphoma	7
Homologous peptides derived from influenza A, B and C viruses induce variable CD8⁺ T cell responses with cross‐reactive potential	7
Parallel detection of SARS‐CoV‐2 epitopes reveals dynamic immunodominance profiles of CD8⁺ T memory cells in convalescent COVID‐19 donors	7
A scalable serology solution for profiling humoral immune responses to SARS‐CoV‐2 infection and vaccination	7
	7
Elevated high‐density lipoprotein levels following acute graft‐versus‐host disease onset: a potential link to T‐cell dysfunction and increased relapse risk	7
CD8⁺ T cell epitope conservation in emerging H5N1 viruses suggests global protection	7
Glucocorticoid regulation of the mTORC1 pathway modulates CD4⁺ T cell responses during infection	7
SARS‐CoV ‐2 triggers complement activation through interactions with heparan sulfate	7
Glycolipid‐peptide conjugate vaccines elicit CD8⁺ T‐cell responses and prevent breast cancer metastasis	6
Modelling the tumor immune microenvironment for precision immunotherapy	6
	6
Enhanced and complementary benefits of a nalfurafine and fingolimod combination to treat immune‐driven demyelination	6
	6
A novel dual NLRP1 and NLRP3 inflammasome inhibitor for the treatment of inflammatory diseases	6
	6
Off‐target effects of bacillus Calmette–Guérin vaccination on immune responses to SARS‐CoV‐2: implications for protection against severe COVID‐19	6
Early CRP kinetics to predict long‐term efficacy of first‐line immune‐checkpoint inhibition combination therapies in metastatic renal cell carcinoma: an updated multicentre real‐world experience apply	6
Epstein–Barr virus and multiple sclerosis: moving from questions of association to questions of mechanism	5
	5
	5
LUNG group 2 innate lymphoid cells as a new adjuvant target to enhance intranasal vaccine efficacy against influenza	5
	5
Improving thymus implantation for congenital athymia with interleukin‐7	5
	5
The frequency of Treg subsets distinguishes disease activity in ANCA vasculitis	5
Naturally derived cytokine peptides limit virus replication and severe disease during influenza A virus infection	5
The immunopathogenesis of SARS‐CoV‐2 infection in children: diagnostics, treatment and prevention	5
Epstein–Barr virus and multiple sclerosis: the dawn of a new age	5
Diversification and shared features of tumor‐binding antibody repertoires in tumor, sentinel lymph node and blood of three patients with breast cancer	5
Engineered iPSC ‐derived natural killer cells: recent innovations in translational innate anti‐cancer immunotherapy	5
	4
The role of immunochemotherapy maintenance in metastatic nasopharyngeal carcinoma: insights from a cohort study in an endemic region	4
Genomic and tumour microenvironmental biomarkers of immune checkpoint inhibitor response in advanced Taiwanese melanoma	4
SARS‐CoV‐2‐infected human airway epithelial cell cultures uniquely lack interferon and immediate early gene responses caused by other coronaviruses	4
Targeting CD38 with monoclonal antibodies disrupts key survival pathways in paediatric Burkitt's lymphoma malignant B cells	4
From the bench to the clinic: basophils and type 2 epithelial cytokines of thymic stromal lymphopoietin and IL‐33	4
γδ T cell characterisation in the long term after haematopoietic stem cell transplantation and its impact on CMV control and cGVHD severity	4
Serum AZD7442 (tixagevimab–cilgavimab) concentrations and in vitroIC₅₀ values predict SARS‐CoV‐2 neutralising antibody titres	4
Inflammatory cytokines as mediators of retinal endothelial barrier dysfunction in non‐infectious uveitis	4
Long‐lasting changes in circulating dendritic cell and monocyte subsets, and altered expression of EMR2, CD97 and EMR3 on these cells in the posttraumatic course	4
Roadmap for understanding mechanisms on how Epstein–Barr virus triggers multiple sclerosis and for translating these discoveries in clinical trials	4
	4
Lymphocyte activation gene 3 served as a potential prognostic and immunological biomarker across various cancer types: a clinical and pan‐cancer analysis	4
Enhancing CAR T‐cell therapy manufacturing efficiency through semi‐automated bioprocessing	4
Anti‐C1q autoantibodies from systemic lupus erythematosus patients enhance CD40–CD154‐mediated inflammation in peripheral blood mononuclear cells in vitro	4
	4
Data standards for single‐cell RNA‐sequencing of paediatric cancer	3
Coexistence of SAPHO syndrome and IgG4‐related disease with Upadacitinib	3
	3
Circulating CCR6⁺ILC proportions are lower in multiple sclerosis patients	3
Targeting the tumor microenvironment in cholangiocarcinoma to improve immune checkpoint blockade: potential strategies and translational pre‐clinical models	3
DROSHA but not DICER is required for human haematopoietic stem cell function	3
Low‐level human memory T and B cells recognising avian influenza hemagglutinins are poorly responsive to existing seasonal influenza vaccines	3
Plasma SARS‐CoV‐2 RNA elimination and RAGE kinetics distinguish COVID‐19 severity	3
Elevated BMI reduces the humoral response to SARS‐CoV‐2 infection	3
Engineered CAR‐T cells targeting the non‐functional P2X purinoceptor 7 (P2X7) receptor as a novel treatment for ovarian cancer	3
Humoral immunity against SARS‐CoV‐2 variants including omicron in solid organ transplant recipients after three doses of a COVID‐19 mRNA vaccine	3
Whole transcriptome profiling of placental pathobiology in SARS‐CoV‐2 pregnancies identifies placental dysfunction signatures	3
Cellular hierarchy for understanding heterogeneity of acute myeloid leukaemia with t(8;21)/RUNX1‐RUNX1T1	3
Chimeric antigen receptor T cells in the fast lane among autoimmune disease therapies	3
	3
A case of T‐cell‐Epstein–Barr virus‐haemophagocytic lymphohistiocytosis and sustained remission following ruxolitinib therapy	3
Lack of immunogenicity for an influenza‐derived peptide across the HLA‐B44 supertype molecules	3
The contribution of the CRP/CD64 axis to renal cancer progression by inducing protumor activation of tumor‐associated macrophages	3
	3