OOIR: Observatory of International Research

Papers

(The median citation count of Clinical & Translational Immunology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
	100
	86
The spectrum of B cells in the pathogenesis, diagnosis and therapeutic applications of immunoglobulin G4‐related disease	42
Circulating cytokine and chemokine patterns associated with cytomegalovirus reactivation after stem cell transplantation	36
SARS‐CoV‐2‐associated T‐cell infiltration in the central nervous system	34
Characteristics of PD‐1⁺CD4⁺ T cells in peripheral blood and synovium of rheumatoid arthritis patients	30
Biomarkers to predict and diagnose pulmonary complications in children post haematopoietic stem cell transplant	28
Impact of adaptive natural killer cells, KLRC2 genotype and cytomegalovirus reactivation on late mortality in patients with severe COVID‐19 lung disease	27
	25
	25
	23
Mass cytometry analysis reveals altered immune profiles in patients with coronary artery disease	22
Effects of extremely preterm birth on cytokine and chemokine responses induced by T‐cell activation during infancy	22
Heterologous booster vaccination with CoronaVac following prime vaccination with mRNA vaccine	22
The contribution of the alternative pathway in complement activation on cell surfaces depends on the strength of classical pathway initiation	22
Endogenous bystander killing mechanisms enhance the activity of novel FAP‐specific CAR‐T cells against glioblastoma	21
Targeting BMI‐1 to deplete antibody‐secreting cells in autoimmunity	19
Validation and performance of a multiplex serology assay to quantify antibody responses following SARS‐CoV‐2 infection or vaccination	19
Retrospective analysis of the efficacy of adjuvant cytokine‐induced killer cell immunotherapy combined with chemotherapy in colorectal cancer patients after surgery	19
	19
Siglec‐1, an easy and contributory inflammation marker in rheumatology	18
Inhibitory effect of hydroxychloroquine on glucocorticoid‐induced osteoporosis in lupus therapy	17
Increased mast cell activation in eosinophilic chronic obstructive pulmonary disease	17
Naturally acquired adaptive immunity to Streptococcus pneumoniae is impaired in rheumatoid arthritis patients	17
	16

	16
High KRT17 expression in tumour budding indicates immunologically ‘hot’ tumour budding and predicts good survival in patients with colorectal cancer	15
Robust immunity to influenza vaccination in haematopoietic stem cell transplant recipients following reconstitution of humoral and adaptive immunity	15
Identification of polo‐like kinase 1 as a therapeutic target in murine lupus	14
Identification of distinct immune signatures in inclusion body myositis by peripheral blood immunophenotyping using machine learning models	14
Prediction of intravenous immunoglobulin retreatment in children with Kawasaki disease using models combining lymphocyte subset and cytokine profile in an East Asian cohort	13
	13
CD39 expression defines exhausted CD4⁺ T cells associated with poor survival and immune evasion in human gastric cancer	13
Increased amphiregulin expression by CD4⁺ T cells from individuals with asymptomatic Leishmania donovani infection	13
A preclinical study of allogeneic CD19 chimeric antigen receptor double‐negative T cells as an off‐the‐shelf immunotherapy drug against B‐cell malignancies	13
Exploring NK cell receptor dynamics in paediatric leukaemias: implications for immunotherapy and prognosis	13
Data standards for single‐cell RNA‐sequencing of paediatric cancer	13
Hypoxia‐inducible factor‐1α regulates the interleukin‐6 production by B cells in rheumatoid arthritis	12
Epstein–Barr virus infection, B‐cell dysfunction and other risk factors converge in gut‐associated lymphoid tissue to drive the immunopathogenesis of multiple sclerosis: a hypothesis	12
	12
Immunoregulatory effects of testosterone supplementation combined with exercise training in men with Inclusion Body Myositis: a double‐blind, placebo‐controlled, cross‐over trial	12
	12
A unique cytotoxic CD4⁺ T cell‐signature defines critical COVID‐19	11
Targeting SARS‐CoV‐2 infection through CAR‐T‐like bispecific T cell engagers incorporating ACE2	11
Pulmonary complications post allogeneic haematopoietic stem cell transplant in children	11
Genome‐wide off‐target analyses of CRISPR/Cas9‐mediated T‐cell receptor engineering in primary human T cells	11
	10
Administration of an LXR agonist promotes atherosclerotic lesion remodelling in murine inflammatory arthritis	10
Effect of washed versus unwashed red blood cells on transfusion‐related immune responses in preterm newborns	10
Inflammasome activation: from molecular mechanisms to autoinflammation	10
	10
Importance of crosstalk between the microbiota and the neuroimmune system for tissue homeostasis	10
Adoptive T‐cell therapy targeting Epstein–Barr virus as a treatment for multiple sclerosis	10
Spatial proteomic profiling of tumor and stromal compartments in non‐small‐cell lung cancer identifies signatures associated with overall survival	9
Infiltrating characteristics and prognostic value of tertiary lymphoid structures in resected gastric neuroendocrine neoplasm patients	9
Serological responses and clinical outcomes following a three‐dose primary COVID‐19 vaccine schedule in kidney transplant recipients and people on dialysis	9
Effect of Bacille Calmette–Guérin vaccination on immune responses to SARS‐CoV‐2 and COVID‐19 vaccination	9
Multi‐omics integration reveals a nonlinear signature that precedes progression of lung fibrosis	9
Blood transcriptomics identifies immune signatures indicative of infectious complications in childhood cancer patients with febrile neutropenia	8
Homologous peptides derived from influenza A, B and C viruses induce variable CD8⁺ T cell responses with cross‐reactive potential	8
Allogeneic haematopoietic stem cell transplantation resets T‐ and B‐cell compartments in sickle cell disease patients	8
Understanding the tumor microenvironment in head and neck squamous cell carcinoma	8
Memory stem T cells modified with a redesigned CD30‐chimeric antigen receptor show an enhanced antitumor effect in Hodgkin lymphoma	8
Sex‐bias in CD8⁺ T‐cell stemness and exhaustion in cancer	8
Graft CD8 T‐cell‐based risk system predicts survival in antithymocyte globulin‐based myeloablative haploidentical peripheral blood stem cell transplantation	8
CD8⁺ T cell epitope conservation in emerging H5N1 viruses suggests global protection	7
SARS‐CoV‐2 triggers complement activation through interactions with heparan sulfate	7
Parallel detection of SARS‐CoV‐2 epitopes reveals dynamic immunodominance profiles of CD8⁺ T memory cells in convalescent COVID‐19 donors	7
Glucocorticoid regulation of the mTORC1 pathway modulates CD4⁺ T cell responses during infection	7
Modelling the tumor immune microenvironment for precision immunotherapy	7
	7
Antigen‐specific polyfunctional cytotoxic T cells differentiate intraocular from peripheral blood immune responses in posterior uveitis	7
	7
A scalable serology solution for profiling humoral immune responses to SARS‐CoV‐2 infection and vaccination	7
A novel dual NLRP1 and NLRP3 inflammasome inhibitor for the treatment of inflammatory diseases	6

Enhanced and complementary benefits of a nalfurafine and fingolimod combination to treat immune‐driven demyelination	6
	6
Early CRP kinetics to predict long‐term efficacy of first‐line immune‐checkpoint inhibition combination therapies in metastatic renal cell carcinoma: an updated multicentre real‐world experience apply	6
Glycolipid‐peptide conjugate vaccines elicit CD8⁺ T‐cell responses and prevent breast cancer metastasis	6
Off‐target effects of bacillus Calmette–Guérin vaccination on immune responses to SARS‐CoV‐2: implications for protection against severe COVID‐19	6
	5
	5
Engineered iPSC‐derived natural killer cells: recent innovations in translational innate anti‐cancer immunotherapy	5
Improving thymus implantation for congenital athymia with interleukin‐7	5
Epstein–Barr virus and multiple sclerosis: the dawn of a new age	5
The immunopathogenesis of SARS‐CoV‐2 infection in children: diagnostics, treatment and prevention	5
Naturally derived cytokine peptides limit virus replication and severe disease during influenza A virus infection	5
Epstein–Barr virus and multiple sclerosis: moving from questions of association to questions of mechanism	5
	5
	5
LUNG group 2 innate lymphoid cells as a new adjuvant target to enhance intranasal vaccine efficacy against influenza	4
Serum AZD7442 (tixagevimab–cilgavimab) concentrations and in vitroIC₅₀ values predict SARS‐CoV‐2 neutralising antibody titres	4
γδ T cell characterisation in the long term after haematopoietic stem cell transplantation and its impact on CMV control and cGVHD severity	4
Roadmap for understanding mechanisms on how Epstein–Barr virus triggers multiple sclerosis and for translating these discoveries in clinical trials	4
Diversification and shared features of tumor‐binding antibody repertoires in tumor, sentinel lymph node and blood of three patients with breast cancer	4
Genomic and tumour microenvironmental biomarkers of immune checkpoint inhibitor response in advanced Taiwanese melanoma	4
Lymphocyte activation gene 3 served as a potential prognostic and immunological biomarker across various cancer types: a clinical and pan‐cancer analysis	4
The frequency of Treg subsets distinguishes disease activity in ANCA vasculitis	4
	4
The role of immunochemotherapy maintenance in metastatic nasopharyngeal carcinoma: insights from a cohort study in an endemic region	4
SARS‐CoV‐2‐infected human airway epithelial cell cultures uniquely lack interferon and immediate early gene responses caused by other coronaviruses	4
Inflammatory cytokines as mediators of retinal endothelial barrier dysfunction in non‐infectious uveitis	4
	4
	3
From the bench to the clinic: basophils and type 2 epithelial cytokines of thymic stromal lymphopoietin and IL‐33	3
Anti‐C1q autoantibodies from systemic lupus erythematosus patients enhance CD40–CD154‐mediated inflammation in peripheral blood mononuclear cells in vitro	3
Plasma SARS‐CoV‐2 RNA elimination and RAGE kinetics distinguish COVID‐19 severity	3
Targeting CD38 with monoclonal antibodies disrupts key survival pathways in paediatric Burkitt's lymphoma malignant B cells	3
	3
Data standards for single‐cell RNA‐sequencing of paediatric cancer	3
DROSHA but not DICER is required for human haematopoietic stem cell function	3
Cellular hierarchy for understanding heterogeneity of acute myeloid leukaemia with t(8;21)/RUNX1‐RUNX1T1	3
	3
Enhancing CAR T‐cell therapy manufacturing efficiency through semi‐automated bioprocessing	3
Long‐lasting changes in circulating dendritic cell and monocyte subsets, and altered expression of EMR2, CD97 and EMR3 on these cells in the posttraumatic course	3
Elevated BMI reduces the humoral response to SARS‐CoV‐2 infection	3
Distinct MAIT cell phenotypes associated with sepsis clinical outcome in emergency department patients	2
Inhibition of renal fibrosis with a human CXCL9‐derived glycosaminoglycan‐binding peptide	2
Allogeneic CD20‐targeted γδ T cells exhibit innate and adaptive antitumor activities in preclinical B‐cell lymphoma models	2
Plasma EBV quantification is associated with the efficacy of immune checkpoint blockade and disease monitoring in patients with primary pulmonary lymphoepithelioma‐like carcinoma	2
Detailed bladder cancer immunoprofiling reveals new clues for immunotherapeutic strategies	2
Squamous cell carcinoma is associated with reduced IL34 expression, alterations in the Langerhans cell antigen‐processing‐presentation machinery and poor patient survival	2
Engineered CAR‐T cells targeting the non‐functional P2X purinoceptor 7 (P2X7) receptor as a novel treatment for ovarian cancer	2
Circulating CCR6⁺ILC proportions are lower in multiple sclerosis patients	2
Primary SARS‐CoV‐2 infection in children and adults results in similar Fc‐mediated antibody effector function patterns	2
Siglec‐7 and Siglec‐9 expression in primary triple negative and oestrogen receptor positive breast cancer and in vitro signalling	2
Early‐like differentiation status of systemic PD‐1⁺CD8⁺ T cells predicts PD‐1 blockade outcome in non‐small cell lung cancer	2
CD137 deficiency because of two novel biallelic TNFRSF9 mutations in a patient presenting with severe EBV‐associated lymphoproliferative disease	2
Metabolic requirements of CD160 expressing memory‐like NK cells in Gram‐negative bacterial infection	2
G‐CSF induces CD15⁺ CD14⁺ cells from granulocytes early in the physiological environment of pregnancy and the cancer immunosuppressive microenvironment	2
Humoral immunity against SARS‐CoV‐2 variants including omicron in solid organ transplant recipients after three doses of a COVID‐19 mRNA vaccine	2
Antibody glycosylation correlates with disease progression in SIV‐Mycobacterium tuberculosis coinfected cynomolgus macaques	2
Chimeric antigen receptor T cells in the fast lane among autoimmune disease therapies	2
A case of T‐cell‐Epstein–Barr virus‐haemophagocytic lymphohistiocytosis and sustained remission following ruxolitinib therapy	2
Improving diagnosis in patients with obstetric antiphospholipid syndrome through the evaluation of non‐criteria antibodies	2
Probabilistic classification of anti‐SARS‐CoV‐2 antibody responses improves seroprevalence estimates	2
A phase II study to evaluate the safety and efficacy of anlotinib combined with toripalimab for advanced biliary tract cancer	2
Circulating CD8⁺ mucosal‐associated invariant T cells correlate with improved treatment responses and overall survival in anti‐PD‐1‐treated melanoma patients	2
Humoral and cellular immune responses in vaccinated and unvaccinated children following SARS‐CoV‐2 Omicron infection	2
Advances in bacteria‐based drug delivery systems for anti‐tumor therapy	2
The contribution of the CRP/CD64 axis to renal cancer progression by inducing protumor activation of tumor‐associated macrophages	2
	2
Whole transcriptome profiling of placental pathobiology in SARS‐CoV‐2 pregnancies identifies placental dysfunction signatures	2