OOIR: Observatory of International Research

Papers

(The median citation count of Clinical & Translational Immunology is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Intimal macrophages develop from circulating monocytes during vasculitis	94
	76
Multi‐omics integration reveals a nonlinear signature that precedes progression of lung fibrosis	37
Early‐like differentiation status of systemic PD‐1⁺CD8⁺ T cells predicts PD‐1 blockade outcome in non‐small cell lung cancer	33
The spectrum of B cells in the pathogenesis, diagnosis and therapeutic applications of immunoglobulin G4‐related disease	28
	26
Administration of an LXR agonist promotes atherosclerotic lesion remodelling in murine inflammatory arthritis	25
Probabilistic classification of anti‐SARS‐CoV‐2 antibody responses improves seroprevalence estimates	25
	23
Inhibition of renal fibrosis with a human CXCL9‐derived glycosaminoglycan‐binding peptide	22
Serological responses and clinical outcomes following a three‐dose primary COVID‐19 vaccine schedule in kidney transplant recipients and people on dialysis	21
Cord blood granulocyte levels are associated with severe bronchiolitis in the first year of life	19
Spatial proteomic profiling of tumor and stromal compartments in non‐small‐cell lung cancer identifies signatures associated with overall survival	19
Siglec‐7 and Siglec‐9 expression in primary triple negative and oestrogen receptor positive breast cancer and in vitro signalling	18
Circulating cytokine and chemokine patterns associated with cytomegalovirus reactivation after stem cell transplantation	17
Diversification and shared features of tumor‐binding antibody repertoires in tumor, sentinel lymph node and blood of three patients with breast cancer	17
	16
LUNG group 2 innate lymphoid cells as a new adjuvant target to enhance intranasal vaccine efficacy against influenza	16
	16
	15
IL‐15‐induced CD38⁺HLA‐DR⁺CD8⁺ T cells correlate with liver injury via NKG2D in chronic hepatitis B cirrhosis	15
Characteristics of PD‐1⁺CD4⁺ T cells in peripheral blood and synovium of rheumatoid arthritis patients	15
Inverse relationship between Fusobacterium nucleatum amount and tumor CD274 (PD‐L1) expression in colorectal carcinoma	14
Impact of adaptive natural killer cells, KLRC2 genotype and cytomegalovirus reactivation on late mortality in patients with severe COVID‐19 lung disease	14
Primary SARS‐CoV‐2 infection in children and adults results in similar Fc‐mediated antibody effector function patterns	12

Autologous Epstein–Barr virus‐specific adoptive T‐cell therapy in a patient with lupus nephritis	12
Naturally derived cytokine peptides limit virus replication and severe disease during influenza A virus infection	12
SARS‐CoV‐2‐associated T‐cell infiltration in the central nervous system	12
Biomarkers to predict and diagnose pulmonary complications in children post haematopoietic stem cell transplant	11
Organ‐on‐chip for advancing CAR therapy	10
Advances in bacteria‐based drug delivery systems for anti‐tumor therapy	10
Dopaminergic regulation of inflammation and immunity in Parkinson's disease: friend or foe?	10
Dual CD47 and PD‐L1 blockade elicits anti‐tumor immunity by intratumoral CD8⁺ T cells	10
The frequency of Treg subsets distinguishes disease activity in ANCA vasculitis	10
Roadmap for understanding mechanisms on how Epstein–Barr virus triggers multiple sclerosis and for translating these discoveries in clinical trials	9
Infiltrating characteristics and prognostic value of tertiary lymphoid structures in resected gastric neuroendocrine neoplasm patients	9
Adoptive T‐cell therapy targeting Epstein–Barr virus as a treatment for multiple sclerosis	9
Allogeneic CD20‐targeted γδ T cells exhibit innate and adaptive antitumor activities in preclinical B‐cell lymphoma models	9
Humoral and cellular immune responses in vaccinated and unvaccinated children following SARS‐CoV‐2 Omicron infection	9
Human regulatory T cells locally differentiate and are functionally heterogeneous within the inflamed arthritic joint	8
	8
Allogeneic haematopoietic stem cell transplantation resets T‐ and B‐cell compartments in sickle cell disease patients	8
Distinct MAIT cell phenotypes associated with sepsis clinical outcome in emergency department patients	8
Anti‐signal recognition particle antibodies induce cardiac diastolic dysfunction via oxidative stress injury	8
	8
	8
	8
Improving diagnosis in patients with obstetric antiphospholipid syndrome through the evaluation of non‐criteria antibodies	7
Blood transcriptomics identifies immune signatures indicative of infectious complications in childhood cancer patients with febrile neutropenia	7
	7
	7
Retrospective analysis of the efficacy of adjuvant cytokine‐induced killer cell immunotherapy combined with chemotherapy in colorectal cancer patients after surgery	7
From the bench to the clinic: basophils and type 2 epithelial cytokines of thymic stromal lymphopoietin and IL‐33	7
The interaction between Epstein–Barr virus and multiple sclerosis genetic risk loci: insights into disease pathogenesis and therapeutic opportunities	7
γδ T cells mediate robust anti‐HIV functions during antiretroviral therapy regardless of immune checkpoint expression	6
Graft CD8 T‐cell‐based risk system predicts survival in antithymocyte globulin‐based myeloablative haploidentical peripheral blood stem cell transplantation	6
Individualised adjuvant immunotherapy with neoantigen‐reactive T cells for gastric signet‐ring cell carcinoma	6
Pretreatment albumin is a prognostic and predictive biomarker for response to atezolizumab across solid tumors	6
Serum AZD7442 (tixagevimab–cilgavimab) concentrations and in vitroIC₅₀ values predict SARS‐CoV‐2 neutralising antibody titres	6
	6
Inflammatory cytokines as mediators of retinal endothelial barrier dysfunction in non‐infectious uveitis	6
The contribution of the alternative pathway in complement activation on cell surfaces depends on the strength of classical pathway initiation	6
Understanding the tumor microenvironment in head and neck squamous cell carcinoma	6
Graft‐versus‐leukaemia immunity is retained following treatment with post‐transplant cyclophosphamide alone or combined with tocilizumab in humanised mice	5
Sex‐bias in CD8⁺ T‐cell stemness and exhaustion in cancer	5
From intramuscular to nasal: unleashing the potential of nasal spray vaccines against coronavirus disease 2019	5
	5
CD137 deficiency because of two novel biallelic TNFRSF9 mutations in a patient presenting with severe EBV‐associated lymphoproliferative disease	5
Homologous peptides derived from influenza A, B and C viruses induce variable CD8⁺ T cell responses with cross‐reactive potential	5
Effects of extremely preterm birth on cytokine and chemokine responses induced by T‐cell activation during infancy	5
Previous SARS‐CoV‐2 infection or a third dose of vaccine elicited cross‐variant neutralising antibodies in vaccinated solid‐organ transplant recipients	4
Mass cytometry analysis reveals altered immune profiles in patients with coronary artery disease	4
Characterisation of novel influenza‐derived HLA‐B*18:01‐restricted epitopes	4
	4
Heterologous booster vaccination with CoronaVac following prime vaccination with mRNA vaccine	4

Assessment of antibodies in the upper and lower human respiratory tract at steady state and after respiratory viral infection	4
SARS‐CoV‐2‐infected human airway epithelial cell cultures uniquely lack interferon and immediate early gene responses caused by other coronaviruses	4
Targeting BMI‐1 to deplete antibody‐secreting cells in autoimmunity	3
	3
Circulating CD8⁺ mucosal‐associated invariant T cells correlate with improved treatment responses and overall survival in anti‐PD‐1‐treated melanoma patients	3
Metabolic requirements of CD160 expressing memory‐like NK cells in Gram‐negative bacterial infection	3
Lymphocyte activation gene 3 served as a potential prognostic and immunological biomarker across various cancer types: a clinical and pan‐cancer analysis	3
Effect of Bacille Calmette–Guérin vaccination on immune responses to SARS‐CoV‐2 and COVID‐19 vaccination	3
Endogenous bystander killing mechanisms enhance the activity of novel FAP‐specific CAR‐T cells against glioblastoma	3
Quantitative measurement of IgG to SARS‐CoV‐2 antigens using monoclonal antibody‐based enzyme‐linked immunosorbent assays	3
A phase II study to evaluate the safety and efficacy of anlotinib combined with toripalimab for advanced biliary tract cancer	3
Plasma EBV quantification is associated with the efficacy of immune checkpoint blockade and disease monitoring in patients with primary pulmonary lymphoepithelioma‐like carcinoma	2
Detailed bladder cancer immunoprofiling reveals new clues for immunotherapeutic strategies	2
Memory stem T cells modified with a redesigned CD30‐chimeric antigen receptor show an enhanced antitumor effect in Hodgkin lymphoma	2
Glucocorticoid regulation of the mTORC1 pathway modulates CD4⁺ T cell responses during infection	2
	2
Increased mast cell activation in eosinophilic chronic obstructive pulmonary disease	2
The Omega‐6 Lipid pathway shift is associated with neutrophil influx and structural lung damage in early cystic fibrosis lung disease	2
Genomic and tumour microenvironmental biomarkers of immune checkpoint inhibitor response in advanced Taiwanese melanoma	2
Impact of SARS‐CoV‐2 infection on vaccine‐induced immune responses over time	2
	2
Organ‐specific immune response in lethal SARS‐CoV‐2 infection by deep spatial phenotyping	2
γδ T cell characterisation in the long term after haematopoietic stem cell transplantation and its impact on CMV control and cGVHD severity	2
SARS‐CoV‐2 triggers complement activation through interactions with heparan sulfate	2
Validation and performance of a multiplex serology assay to quantify antibody responses following SARS‐CoV‐2 infection or vaccination	2
A new flow cytometry assay identifies recipient IgG subtype antibodies binding donor cells: increasing donor availability for highly sensitised patients	2
Changes in immune cell populations following KappaMab, lenalidomide and low‐dose dexamethasone treatment in multiple myeloma	2
Anti‐C1q autoantibodies from systemic lupus erythematosus patients enhance CD40–CD154‐mediated inflammation in peripheral blood mononuclear cells in vitro	2
Synergistic integration of histone deacetylase inhibitors apparently enhances the cytokine‐induced killer cell efficiency in multiple myeloma via the NKG2D pathway	1
High‐resolution analysis of individual spike peptide‐specific CD4⁺ T‐cell responses in vaccine recipients and COVID‐19 patients	1
	1
Natural killer cell antibody‐dependent cellular cytotoxicity to Plasmodium falciparum is impacted by cellular phenotypes, erythrocyte polymorphisms, parasite diversity and intensity of transmis	1
Inhibitory effect of hydroxychloroquine on glucocorticoid‐induced osteoporosis in lupus therapy	1
Autoimmune uveitis in Behçet's disease and Vogt‐Koyanagi‐Harada disease differ in tissue immune infiltration and T cell clonality	1
JAK1/2 inhibitor ruxolitinib promotes the expansion and suppressive action of polymorphonuclear myeloid‐derived suppressor cells via the JAK/STAT and ROS‐MAPK	1
Whole‐blood cytokine secretion assay as a high‐throughput alternative for assessing the cell‐mediated immunity profile after two doses of an adjuvanted SARS‐CoV‐2 recombinant protein vaccine candidate	1
Modelling the tumor immune microenvironment for precision immunotherapy	1
Genes involved in platelet aggregation and activation are downregulated during acute anaphylaxis in humans	1
Comparison of the tumor microenvironments of squamous cell carcinoma at different anatomical locations within the upper aerodigestive tract in relation to response to ICI therapy	1
G‐CSF induces CD15⁺ CD14⁺ cells from granulocytes early in the physiological environment of pregnancy and the cancer immunosuppressive microenvironment	1
	1
	1
A peptoid interleukin‐15 receptor antagonist suppresses inflammation and arthritis in mice	1
Targeting CD38 with monoclonal antibodies disrupts key survival pathways in paediatric Burkitt's lymphoma malignant B cells	1
CD8⁺ T cell epitope conservation in emerging H5N1 viruses suggests global protection	1
Molecular and cellular mechanisms of itch and pain in atopic dermatitis and implications for novel therapeutics	1
YTHDF2 promotes temozolomide resistance in glioblastoma by activation of the Akt and NF‐κB signalling pathways via inhibiting EPHB3 and TNFAIP3	1
Parallel detection of SARS‐CoV‐2 epitopes reveals dynamic immunodominance profiles of CD8⁺ T memory cells in convalescent COVID‐19 donors	1
	1
Immunoglobulin G genetic variation can confound assessment of antibody levels via altered binding to detection reagents	1
Optimising the IgG‐degrading enzyme treatment regimen for enhanced adeno‐associated virus transduction in the presence of neutralising antibodies	1
Naturally acquired adaptive immunity to Streptococcus pneumoniae is impaired in rheumatoid arthritis patients	1
Plasma SARS‐CoV‐2 RNA elimination and RAGE kinetics distinguish COVID‐19 severity	1
Severe COVID‐19 represents an undiagnosed primary immunodeficiency in a high proportion of infected individuals	1
A scalable serology solution for profiling humoral immune responses to SARS‐CoV‐2 infection and vaccination	1
Circulating CXCR5⁺ natural killer cells are expanded in patients with myasthenia gravis	1
Siglec‐1, an easy and contributory inflammation marker in rheumatology	1
Maintenance of caecal homeostasis by diverse adaptive immune cells in the rhesus macaque	1
Choice of activation protocol impacts the yield and quality of CAR T cell product, particularly with older individuals	1