OOIR: Observatory of International Research

Papers

(The H4-Index of eLife is 99. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants	1134
Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3	826
A connectome and analysis of the adult Drosophila central brain	568
Atomic structures of respiratory complex III2, complex IV, and supercomplex III2-IV from vascular plants	555
Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission	374
Tracking excess mortality across countries during the COVID-19 pandemic with the World Mortality Dataset	300
A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm	289
COVID-19 medical papers have fewer women first authors than expected	270
Quantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithm	263
How to measure and evaluate binding affinities	262
Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics	260
ACE2: Evidence of role as entry receptor for SARS-CoV-2 and implications in comorbidities	249
N501Y mutation of spike protein in SARS-CoV-2 strengthens its binding to receptor ACE2	244
Evidence for transmission of COVID-19 prior to symptom onset	241
DunedinPACE, a DNA methylation biomarker of the pace of aging	234
The connectome of the adult Drosophila mushroom body provides insights into function	222
SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-κB pathway	207
Does the human placenta express the canonical cell entry mediators for SARS-CoV-2?	204
An electrophysiological marker of arousal level in humans	198
DNA damage—how and why we age?	191
Antimicrobial resistance and COVID-19: Intersections and implications	190
Sampling alternative conformational states of transporters and receptors with AlphaFold2	185
A 10-year follow-up study of sex inclusion in the biological sciences	178
Colistin kills bacteria by targeting lipopolysaccharide in the cytoplasmic membrane	176
Lytic transglycosylases mitigate periplasmic crowding by degrading soluble cell wall turnover products	174

Cancer-associated fibroblasts and their influence on tumor immunity and immunotherapy	167
The tumor microenvironment as a metabolic barrier to effector T cells and immunotherapy	166
Inhibition of SARS-CoV-2 viral entry upon blocking N- and O-glycan elaboration	163
Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study	163
A whole-brain connectivity map of mouse insular cortex	162
FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices	162
Cohesin and condensin extrude DNA loops in a cell cycle-dependent manner	159
Structure of the bacterial ribosome at 2 Å resolution	157
Sex differences in biological aging with a focus on human studies	154
A connectome of the Drosophila central complex reveals network motifs suitable for flexible navigation and context-dependent action selection	153
Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition	151
Accurate and versatile 3D segmentation of plant tissues at cellular resolution	151
SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation	151
Neuronal timescales are functionally dynamic and shaped by cortical microarchitecture	148
Standardizing workflows in imaging transcriptomics with the abagen toolbox	145
Modular output circuits of the fastigial nucleus for diverse motor and nonmotor functions of the cerebellar vermis	144
Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males: findings from a nested case-control study	141
The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types	141
A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress	140
Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell	138
Simultaneous trimodal single-cell measurement of transcripts, epitopes, and chromatin accessibility using TEA-seq	138
Mechanistic theory predicts the effects of temperature and humidity on inactivation of SARS-CoV-2 and other enveloped viruses	137
The OpenNeuro resource for sharing of neuroscience data	137
Beyond the RNA-dependent function of LncRNA genes	135
TRex, a fast multi-animal tracking system with markerless identification, and 2D estimation of posture and visual fields	135
Tumor stiffening reversion through collagen crosslinking inhibition improves T cell migration and anti-PD-1 treatment	133
A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes	132
Trends in snakebite deaths in India from 2000 to 2019 in a nationally representative mortality study	130
A single-cell survey of Drosophila blood	129
The genomic consequences of hybridization	128
Viral load and contact heterogeneity predict SARS-CoV-2 transmission and super-spreading events	128
SpikeInterface, a unified framework for spike sorting	128
Reporting and misreporting of sex differences in the biological sciences	126
SON and SRRM2 are essential for nuclear speckle formation	124
Assembly of recombinant tau into filaments identical to those of Alzheimer’s disease and chronic traumatic encephalopathy	123
HP1 proteins compact DNA into mechanically and positionally stable phase separated domains	123
Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes	123
Mapping single-cell atlases throughout Metazoa unravels cell type evolution	121
A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics	121
An open label trial of anakinra to prevent respiratory failure in COVID-19	121
Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens	118
Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation	117
A fully automated high-throughput workflow for 3D-based chemical screening in human midbrain organoids	117
Challenges for assessing replicability in preclinical cancer biology	114
Racial inequity in grant funding from the US National Institutes of Health	114
Metabolic biomarker profiling for identification of susceptibility to severe pneumonia and COVID-19 in the general population	113
An open-source, high-performance tool for automated sleep staging	112
Microglial calcium signaling is attuned to neuronal activity in awake mice	112
A community-maintained standard library of population genetic models	111
Ribosome collisions trigger cis-acting feedback inhibition of translation initiation	110

Investigating the replicability of preclinical cancer biology	110
SARS-CoV-2 entry into human airway organoids is serine protease-mediated and facilitated by the multibasic cleavage site	110
Relationship between simultaneously recorded spiking activity and fluorescence signal in GCaMP6 transgenic mice	108
Training deep neural density estimators to identify mechanistic models of neural dynamics	108
Dynamic metastable long-living droplets formed by sticker-spacer proteins	107
The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals	107
SARS-CoV-2 strategically mimics proteolytic activation of human ENaC	107
Single-nucleus transcriptomic analysis of human dorsal root ganglion neurons	105
Local emergence in Amazonia of Plasmodium falciparum k13 C580Y mutants associated with in vitro artemisinin resistance	105
Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs	104
Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning	104
Highly contiguous assemblies of 101 drosophilid genomes	104
Convalescent COVID-19 patients are susceptible to endothelial dysfunction due to persistent immune activation	103
Lysosome activity is modulated by multiple longevity pathways and is important for lifespan extension in C. elegans	103
Patterns of within-host genetic diversity in SARS-CoV-2	101
Heterogeneity in transmissibility and shedding SARS-CoV-2 via droplets and aerosols	101
A powerful drug combination strategy targeting glutamine addiction for the treatment of human liver cancer	100
Diverse viral proteases activate the NLRP1 inflammasome	100
Generation of vascularized brain organoids to study neurovascular interactions	100
A new genetic strategy for targeting microglia in development and disease	99
Hyperalignment: Modeling shared information encoded in idiosyncratic cortical topographies	99
EDF1 coordinates cellular responses to ribosome collisions	99
Ageing compromises mouse thymus function and remodels epithelial cell differentiation	99
Diversity and asynchrony in soil microbial communities stabilizes ecosystem functioning	99