eLife

Article	Citations
Correction: Highly contiguous assemblies of 101 drosophilid genomes	742
Multi-tiered actions of Legionella effectors to modulate host Rab10 dynamics	441
Molecular and mechanical signatures contributing to mouse epidermal differentiation and barrier formation	334
Apoptotic signaling clears engineered Salmonella in an organ-specific manner	311
Wiring up for controlled flight	294
Deciding when to move	270
Shining a light on hematopoietic stem cells	253
Imaging of brain electric field networks with spatially resolved EEG	251
Caspases promote cell proliferation after necrosis	220
Outgrowing self-denial	186
Correction: Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci	171
Allosteric regulation of kinase activity in living cells	169
Shared functional organization between pulvinar-cortical and cortico-cortical connectivity and its structural and molecular imaging correlates	161
Evolution of hind limb morphology of Titanosauriformes (Dinosauria, Sauropoda) analyzed via 3D geometric morphometrics reveals wide-gauge posture as an exaptation for gigantism	160
scRNA+TCR-seq reveals the proportion and characteristics of dual TCR Treg cells in mouse lymphoid and non-lymphoid tissues	153
Single-cell profiling reveals the intratumor heterogeneity and immunosuppressive microenvironment in cervical adenocarcinoma	152
Space as a scaffold for rotational generalisation of abstract concepts	150
Companion cells with high florigen production express other small proteins and reveal a nitrogen-sensitive FT repressor	148
Correction: Drp1 is required for AgRP neuronal activity and feeding	146
SARS-CoV-2 NSP13 interacts with TEAD to suppress Hippo-YAP signaling	143
DeePosit, an AI-based tool for detecting mouse urine and fecal depositions from thermal video clips of behavioral experiments	140
Horizontally transferred cell-free chromatin particles function as autonomous ‘satellite genomes’ and vehicles for transposable elements within host cells	137
Emerging variants of SARS-CoV-2 NSP10 highlight strong functional conservation of its binding to two non-structural proteins, NSP14 and NSP16	133
Position representations of moving objects align with real-time position in the early visual response	132
A non-bactericidal cathelicidin provides prophylactic efficacy against bacterial infection by driving phagocyte influx	131

Neural geometry from mixed sensorimotor selectivity for predictive sensorimotor control	131
Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster	130
Structural mechanism of strand exchange by the RAD51 filament	129
Memory-specific encoding activities of the ventral tegmental area dopamine and GABA neurons	121
An optogenetic cell therapy to restore control of target muscles in an aggressive mouse model of amyotrophic lateral sclerosis	120
Airway basal cells show regionally distinct potential to undergo metaplastic differentiation	119
Soluble amyloid-β precursor peptide does not regulate GABAB receptor activity	118
Becoming less beige with age	116
Variation in the basal immune state and implications for disease	114
Recombinant single-cycle influenza virus with exchangeable pseudotypes allows repeated immunization to augment anti-tumour immunity with immune checkpoint inhibitors	112
Brain and molecular mechanisms underlying the nonlinear association between close friendships, mental health, and cognition in children	112
Correction: Distinct neurexin-cerebellin complexes control AMPA- and NMDA-receptor responses in a circuit-dependent manner	111
Conduction pathway for potassium through the Escherichia coli pump KdpFABC	110
Removal of developmentally regulated microexons has a minimal impact on larval zebrafish brain morphology and function	109
Chronic hyperactivation of midbrain dopamine neurons causes preferential dopamine neuron degeneration	108
Rapid and inducible mislocalization of endogenous TDP43 in a novel human model of amyotrophic lateral sclerosis	107
Resting natural killer cells promote the progress of colon cancer liver metastasis by elevating tumor-derived stem cell factor	106
CTFFIND5 provides improved insight into quality, tilt, and thickness of TEM samples	103
Differential functions of the dorsal and intermediate regions of the hippocampus for optimal goal-directed navigation in VR space	103
EPHA4 signaling dysregulation links abnormal locomotion and the development of idiopathic scoliosis	102
Cingulate cortex shapes early postnatal development of social vocalizations	100
Reversing protonation of weakly basic drugs greatly enhances intracellular diffusion and decreases lysosomal sequestration	100
Using adopted individuals to partition indirect maternal genetic effects into prenatal and postnatal effects on offspring phenotypes	99
Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme	99
Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes	97
Impact of a human gut microbe on Vibrio cholerae host colonization through biofilm enhancement	97
Decoding the activated stem cell phenotype of the neonatally maturing pituitary	96
A neural progenitor mitotic wave is required for asynchronous axon outgrowth and morphology	96
Regulation of pulmonary surfactant by the adhesion GPCR GPR116/ADGRF5 requires a tethered agonist-mediated activation mechanism	95
T cells discriminate between groups C1 and C2 HLA-C	95
Mg2+-dependent conformational equilibria in CorA and an integrated view on transport regulation	95
Katanin, kinesin-13, and ataxin-2 inhibit premature interaction between maternal and paternal genomes in C. elegans zygotes	94
Altered visual cortex excitatory/inhibitory ratio following transient congenital visual deprivation in humans	94
Nutritional state-dependent modulation of insulin-producing cells in Drosophila	93
A new potential strategy for cutaneous squamous cell carcinoma treatment by generating serum-based antibodies from tumor-exposed mice	93
Muscarinic receptors mediate motivation via preparatory neural activity in humans	92
Astrocytes mediate two forms of spike timing-dependent depression at entorhinal cortex-hippocampal synapses	90
NAB2-STAT6 drives an EGR1-dependent neuroendocrine program in solitary fibrous tumors	89
Immunogenicity and safety of a live-attenuated SARS-CoV-2 vaccine candidate based on multiple attenuation mechanisms	88
DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids	88
Multisensory integration enhances audiovisual responses in the Mauthner cell	87
Differential regulation of the proteome and phosphoproteome along the dorso-ventral axis of the early Drosophila embryo	87
Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape	84
Natural variation in salt-induced changes in root:shoot ratio reveals SR3G as a negative regulator of root suberization and salt resilience in Arabidopsis	84
Evolution of an extreme hemoglobin phenotype contributed to the sub-Arctic specialization of extinct Steller’s sea cows	83
High-resolution imaging of the osteogenic and angiogenic interface at the site of murine cranial bone defect repair via multiphoton microscopy	83
AARS2 ameliorates myocardial ischemia via fine-tuning PKM2-mediated metabolism	83
PIMT is a novel and potent suppressor of endothelial activation	82
Somatic mutation rates scale with time not growth rate in long-lived tropical trees	82
Mechanism of substrate binding and transport in BASS transporters	82

BATF relieves hepatic steatosis by inhibiting PD1 and promoting energy metabolism	81
Interrogating basal ganglia circuit function in people with Parkinson’s disease and dystonia	80
Ligand bias underlies differential signaling of multiple FGFs via FGFR1	80
The molecular mechanism and evolutionary divergence of caspase 3/7-regulated gasdermin E activation	79
An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor	79
An emerging view of neural geometry in motor cortex supports high-performance decoding	79
Goal-directed vocal planning in a songbird	79
Convergence, plasticity, and tissue residence of regulatory T cell response via TCR repertoire prism	79
Self-formation of concentric zones of telencephalic and ocular tissues and directional retinal ganglion cell axons	78
De novo identification of universal cell mechanics gene signatures	78
Genetic screen identified PRMT5 as a neuroprotection target against cerebral ischemia	78
Spatial transformation of multi-omics data unlocks novel insights into cancer biology	78
Linking genotypic and phenotypic changes in the E. coli long-term evolution experiment using metabolomics	77
Antipsychotic drugs selectively decorrelate long-range interactions in deep cortical layers	77
Sensory input-dependent gain modulation of the optokinetic nystagmus by mid-infrared stimulation in pigeons	76
Germinal center B cells that acquire nuclear proteins are specifically suppressed by follicular regulatory T cells	76
Dynamics of co-substrate pools can constrain and regulate metabolic fluxes	76
Are single-peaked tuning curves tuned for speed rather than accuracy?	76
Recalibrating vision-for-action requires years after sight restoration from congenital cataracts	76
A reductionist paradigm for high-throughput behavioural fingerprinting in Drosophila melanogaster	76
Insight into the evolutionary assemblage of cranial kinesis from a Cretaceous bird	75
A chronic signaling TGFb zebrafish reporter identifies immune response in melanoma	75
Osteoclast-mediated resorption primes the skeleton for successful integration during axolotl limb regeneration	74
A randomized multiplex CRISPRi-Seq approach for the identification of critical combinations of genes	74
Scorpionfish BPI is highly active against multiple drug-resistant Pseudomonas aeruginosa isolates from people with cystic fibrosis	74
Functional gradients in the human lateral prefrontal cortex revealed by a comprehensive coordinate-based meta-analysis	73
Intracranial human recordings reveal association between neural activity and perceived intensity for the pain of others in the insula	73
Aberrant FGF signaling promotes granule neuron precursor expansion in SHH subgroup infantile medulloblastoma	72
The effect of transcutaneous auricular vagus nerve stimulation on cardiovascular function in subarachnoid hemorrhage patients: A randomized trial	72
Differential roles of NaV1.2 and NaV1.6 in neocortical pyramidal cell excitability	72
Altered thymic niche synergistically drives the massive proliferation of malignant thymocytes	72
A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective, and anti-inflammatory properties following sta	72
TRPV4 activation by TGFβ2 enhances cellular contractility and drives ocular hypertension	72
Cortico-striatal action control inherent of opponent cognitive-motivational styles	72
Chronic stress impairs autoinhibition in neurons of the locus coeruleus to increase asparagine endopeptidase activity	72
Separable dorsal raphe dopamine projections mimic the facets of a loneliness-like state	72
Paracrine rescue of MYR1-deficient Toxoplasma gondii mutants reveals limitations of pooled in vivo CRISPR screens	71
The influence of temporal context on vision over multiple time scales	71
Hierarchical encoding of natural sound mixtures in ferret auditory cortex	71
Multi-dimensional social relationships shape social attention in monkeys	71
Wag31, a membrane tether, is crucial for lipid homeostasis in mycobacteria	71
Single-cell transcriptomes of zebrafish germline reveal progenitor types and feminization by Foxl2l	70
Function and firing of the Streptomyces coelicolor contractile injection system requires the membrane protein CisA	70
Crystal structure and catalytic mechanism of PL35 family glycosaminoglycan lyases with an ultrabroad substrate spectrum	70
Antagonist actions of CMK-1/CaMKI and TAX-6/calcineurin along the C. elegans thermal avoidance circuit orchestrate adaptation of nociceptive response to repeated stimuli	69
ACVR2A facilitates trophoblast cell invasion through TCF7/c-JUN pathway in pre-eclampsia progression	69
Subtypes and proliferation patterns of small intestine neuroendocrine tumors revealed by single-cell RNA sequencing	69
Cell type-specific driver lines targeting the Drosophila central complex and their use to investigate neuropeptide expression and sleep regulation	69
Iridescent structural coloration in a crested Cretaceous enantiornithine bird from the Jehol Biota	68
Sexual failure decreases sweet taste perception in male Drosophila via dopaminergic signaling	68
Neural excursions from manifold structure explain patterns of learning during human sensorimotor adaptation	68
Phylodynamics of SARS-CoV-2 in France, Europe, and the world in 2020	68
Preclinical systematic review of CCR5 antagonists as cerebroprotective and stroke recovery enhancing agents	68
Functionally important residues from graph analysis of coevolved dynamic couplings	68
Cortical adaptation to sound reverberation	68
Improvement of muscle strength in a mouse model for congenital myopathy treated with HDAC and DNA methyltransferase inhibitors	68
A causal role of the NMDA receptor in recurrent processing during perceptual integration	68
Non-destructive in situ monitoring of structural changes of 3D tumor spheroids during the formation, migration, and fusion process	68
Patterns of interdivision time correlations reveal hidden cell cycle factors	68
SOD1 is a synthetic-lethal target in PPM1D-mutant leukemia cells	67
Biocalcification in porcelaneous foraminifera	67
Guanidine production by plant homoarginine-6-hydroxylases	67
PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification	66
Alternative splicing across the tree of life	66
G protein subunit Gγ13-mediated signaling pathway is critical to the inflammation resolution and functional recovery of severely injured lungs	66
Language experience shapes predictive coding of rhythmic sound sequences	65
Predicting individual traits from models of brain dynamics accurately and reliably using the Fisher kernel	65
Macro-scale patterns in functional connectivity associated with ongoing thought patterns and dispositional traits	65
Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4	65
Pigmentation level of human iPSC-derived RPE does not indicate a specific gene expression profile	65
Serial attentional resource allocation during parallel feature value tracking	64
Human induced pluripotent stem cell-derived cardiomyocytes to study inflammation-induced aberrant calcium transient	64
The domesticated transposon protein L1TD1 associates with its ancestor L1 ORF1p to promote LINE-1 retrotransposition	64
The substrate-binding domains of the osmoregulatory ABC importer OpuA transiently interact	64
Antigenic strain diversity predicts different biogeographic patterns of maintenance and decline of antimalarial drug resistance	64
Emergence of ion-channel-mediated electrical oscillations in Escherichia coli biofilms	64
Short-range interactions between fibrocytes and CD8+ T cells in COPD bronchial inflammatory response	64
Movies reveal the fine-grained organization of infant visual cortex	64
Netrin signaling mediates survival of dormant epithelial ovarian cancer cells	64
The satiety hormone cholecystokinin gates reproduction in fish by controlling gonadotropin secretion	64

Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium	64
Genetic and dietary modulators of the inflammatory response in the gastrointestinal tract of the BXD mouse genetic reference population	63
Pervasive translation in Mycobacterium tuberculosis	63
Using light and X-ray scattering to untangle complex neuronal orientations and validate diffusion MRI	63
Phosphate as an adjunct to calcium in promoting coronary vascular calcification in chronic inflammatory states	63
AARS2 ameliorates myocardial ischemia via fine-tuning PKM2-mediated metabolism	62
Larger but younger fish when growth outpaces mortality in heated ecosystem	62
COVID-19 cluster size and transmission rates in schools from crowdsourced case reports	62
Amelioration of non-alcoholic fatty liver disease by targeting adhesion G protein-coupled receptor F1 (Adgrf1)	62
Interplay between external inputs and recurrent dynamics during movement preparation and execution in a network model of motor cortex	62
Mouthparts of the bumblebee (Bombus terrestris) exhibit poor acuity for the detection of pesticides in nectar	62
Comprehensive mutagenesis maps the effect of all single-codon mutations in the AAV2 rep gene on AAV production	62
Cryo-EM structures of a pentameric ligand-gated ion channel in liposomes	61
The phytoplasma SAP54 effector acts as a molecular matchmaker for leafhopper vectors by targeting plant MADS-box factor SVP	61
RAG1 and RAG2 non-core regions are implicated in leukemogenesis and off-target V(D)J recombination in BCR-ABL1-driven B-cell lineage lymphoblastic leukemia	61
Caveolae and Bin1 form ring-shaped platforms for T-tubule initiation	61
High-grade serous ovarian carcinoma organoids as models of chromosomal instability	61
Computational modeling of threat learning reveals links with anxiety and neuroanatomy in humans	61
The SAFE Labs Handbook as a tool for improving lab culture	61
Asymmetric distribution of color-opponent response types across mouse visual cortex supports superior color vision in the sky	61
circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA	61
S-adenosylmethionine synthases specify distinct H3K4me3 populations and gene expression patterns during heat stress	60
GWAS and ExWAS of blood mitochondrial DNA copy number identifies 71 loci and highlights a potential causal role in dementia	60
Hammerhead-type FXR agonists induce an enhancer RNA Fincor that ameliorates nonalcoholic steatohepatitis in mice	60
Unraveling the link between neuropathy target esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier	60
Oxydifficidin, a potent Neisseria gonorrhoeae antibiotic due to DedA-assisted uptake and ribosomal protein RplL sensitivity	60
Major nuclear locales define nuclear genome organization and function beyond A and B compartments	60
Integrating analog and digital modes of gene expression at Arabidopsis FLC	60
Courtship behaviour reveals temporal regularity is a critical social cue in mouse communication	60
Reliable protein–protein docking with AlphaFold, Rosetta, and replica exchange	59
Targeting the fatty acid binding proteins disrupts multiple myeloma cell cycle progression and MYC signaling	59
osl-dynamics, a toolbox for modeling fast dynamic brain activity	59
Single-cell transcriptomic atlas of lung microvascular regeneration after targeted endothelial cell ablation	59
Muscle-resident mesenchymal progenitors sense and repair peripheral nerve injury via the GDNF-BDNF axis	58
Estradiol elicits distinct firing patterns in arcuate nucleus kisspeptin neurons of females through altering ion channel conductances	58
New insights into anatomical connectivity along the anterior–posterior axis of the human hippocampus using in vivo quantitative fibre tracking	58
Hydrop enables droplet-based single-cell ATAC-seq and single-cell RNA-seq using dissolvable hydrogel beads	58
Nucleosome wrapping energy in CpG islands and the role of epigenetic base modifications	58
A new early branching armored dinosaur from the Lower Jurassic of southwestern China	58
Rab7-dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis	58
Evidence accumulation, not ‘self-control’, explains dorsolateral prefrontal activation during normative choice	57
A ‘double-edged’ role for type-5 metabotropic glutamate receptors in pain disclosed by light-sensitive drugs	57
How honey bees make fast and accurate decisions	57
Evolutionary rate covariation is a reliable predictor of co-functional interactions but not necessarily physical interactions	57
Identification of a GABAergic neural circuit governing leptin signaling deficiency-induced obesity	57
Galvanic current activates the NLRP3 inflammasome to promote Type I collagen production in tendon	57
Peroxiredoxin 5 regulates osteogenic differentiation through interaction with hnRNPK during bone regeneration	57
Cryo-electron tomographic investigation of native hippocampal glutamatergic synapses	57
A direct neural signature of serial dependence in working memory	57
The deep-rooted origin of disulfide-rich spider venom toxins	57
Long COVID in cancer patients: preponderance of symptoms in majority of patients over long time period	56
Whole genomes from the extinct Xerces Blue butterfly can help identify declining insect species	56
Antisense oligonucleotide therapy rescues disturbed brain rhythms and sleep in juvenile and adult mouse models of Angelman syndrome	56
Maresin 1 repletion improves muscle regeneration after volumetric muscle loss	56
p38γ and p38δ modulate innate immune response by regulating MEF2D activation	56
The non-muscle actinopathy-associated mutation E334Q in cytoskeletal γ-actin perturbs interaction of actin filaments with myosin and ADF/cofilin family proteins	56
Medial anterior prefrontal cortex stimulation downregulates implicit reactions to threats and prevents the return of fear	56
Human promoter directionality is determined by transcriptional initiation and the opposing activities of INTS11 and CDK9	56
Fitness advantage of Bacteroides thetaiotaomicron capsular polysaccharide in the mouse gut depends on the resident microbiota	56
Genetic and karyotype divergence between parents affect clonality and sterility in hybrids	56
Nucleotide-level linkage of transcriptional elongation and polyadenylation	56
Nonlinear feedback modulation contributes to the optimization of flexible decision-making	56
Impact of maximal overexpression of a non-toxic protein on yeast cell physiology	56
Pyruvate and related energetic metabolites modulate resilience against high genetic risk for glaucoma	56
Cellular and molecular dynamics in the lungs of neonatal and juvenile mice in response to E. coli	56
Conditional and unconditional components of aversively motivated freezing, flight and darting in mice	56
Dynamic analysis of circulating tumor DNA to predict the prognosis and monitor the treatment response of patients with metastatic triple-negative breast cancer: A prospective study	56
Lonafarnib improves cardiovascular function and survival in a mouse model of Hutchinson-Gilford progeria syndrome	56
Constitutively active receptor ADGRA3 signaling induces adipose thermogenesis	56
A computationally informed comparison between the strategies of rodents and humans in visual object recognition	56
Applying 3D correlative structured illumination microscopy and X-ray tomography to characterise herpes simplex virus-1 morphogenesis	56
β-Glucan reprograms alveolar macrophages via neutrophil/IFNγ axis in a murine model of lung injury	56
High-throughput Plasmodium falciparum hrp2 and hrp3 gene deletion typing by digital PCR to monitor malaria rapid diagnostic test efficacy	55
Functional visualization of NK cell-mediated killing of metastatic single tumor cells	55
Cervical cancer screening improvements with self-sampling during the COVID-19 pandemic	55
Intrinsic excitability mechanisms of neuronal ensemble formation	55
Intestinal GCN2 controls Drosophila systemic growth in response to Lactiplantibacillus plantarum symbiotic cues encoded by r/tRNA operons	55
Sex differences and sex bias in human circadian and sleep physiology research	55
Early steps of protein disaggregation by Hsp70 chaperone and class B J-domain proteins are shaped by Hsp110	55
Mutant SF3B1 promotes malignancy in PDAC	55
SAFB regulates hippocampal stem cell fate by targeting Drosha to destabilize Nfib mRNA	55
State-dependent representations of mixtures by the olfactory bulb	55
An annotated introductory reading list for neurodiversity	54
Best practices to promote rigor and reproducibility in the era of sex-inclusive research	54
Ketamine induces multiple individually distinct whole-brain functional connectivity signatures	54
Spatial transcriptomics reveals metabolic changes underly age-dependent declines in digit regeneration	54
A connectomics-based taxonomy of mammals	54
An antagonism between Spinophilin and Syd-1 operates upstream of memory-promoting presynaptic long-term plasticity	54
A meta-analysis of the association between male dimorphism and fitness outcomes in humans	54
Activating SRC/MAPK signaling via 5-HT1A receptor contributes to the effect of vilazodone on improving thrombocytopenia	54
Combining mutation and recombination statistics to infer clonal families in antibody repertoires	53
Septins function in exocytosis via physical interactions with the exocyst complex in fission yeast cytokinesis	53
Synergistic phase separation of two pathways promotes integrin clustering and nascent adhesion formation	53
Direct observation of the neural computations underlying a single decision	53
The ER tether VAPA is required for proper cell motility and anchors ER-PM contact sites to focal adhesions	53