Acta Neuropathologica Communications

Article	Citations
Correction: Cleaved TMEM106B forms amyloid aggregates in central and peripheral nervous systems	163
A novel case of glial transdifferentiation in renal medullary carcinoma brain metastasis	153
Early inner plexiform layer thinning and retinal nerve fiber layer thickening in excitotoxic retinal injury using deep learning-assisted optical coherence tomography	147
Mitochondrial DNA mutations in Medulloblastoma	121
Retina-to-brain spreading of α-synuclein after intravitreal injection of preformed fibrils	120
Neutrophils predominate the immune signature of cerebral thrombi in COVID-19 stroke patients	118
The neuropathologic findings in a case of progressive cavitating leukoencephalopathy due to NDUFV1 pathogenic variants	99
Cognitively impaired aged Octodon degus recapitulate major neuropathological features of sporadic Alzheimer’s disease	88
Novel histotypes of sporadic Creutzfeldt–Jakob disease linked to 129MV genotype	75
Severe ACTA1-related nemaline myopathy: intranuclear rods, cytoplasmic bodies, and enlarged perinuclear space as characteristic pathological features on muscle biopsies	75
NAD salvage pathway machinery expression in normal and glaucomatous retina and optic nerve	74
Clinico-pathological and epigenetic heterogeneity of diffuse gliomas with FGFR3::TACC3 fusion	68
Immunological and tumor-intrinsic mechanisms mediate the synergistic growth suppression of experimental glioblastoma by radiotherapy and MET inhibition	63
Cortical microvascular raspberries and ageing: an independent but not exclusive relationship	63
Accurate digital quantification of tau pathology in progressive supranuclear palsy	60
MGMT methylation pattern of long-term and short-term survivors of glioblastoma reveals CpGs of the enhancer region to be of high prognostic value	59
Genetic ablation of Sarm1 attenuates expression and mislocalization of phosphorylated TDP-43 after mouse repetitive traumatic brain injury	58
Histone acetylation in an Alzheimer’s disease cell model promotes homeostatic amyloid-reducing pathways	57
Rise and fall of peroxisomes during Alzheimer´s disease: a pilot study in human brains	56
Potential prognostic determinants for FET::CREB fusion-positive intracranial mesenchymal tumor	54
Beyond genetics: including the environmental dimension in amyloidosis mouse models for Alzheimer’s disease	52
Rare germline variants in POLE and POLD1 encoding the catalytic subunits of DNA polymerases ε and δ in glioma families	51
Focal amyloid and asymmetric tau in an imaging-to-autopsy case of clinical primary progressive aphasia with Alzheimer disease neuropathology	50
Pleomorphic xanthoastrocytoma in the multiverse of epigenomics: is it time to recognize the variants?	49
Pathological changes induced by Alzheimer’s brain inoculation in amyloid-beta plaque-bearing mice	49

DNA hypomethylator phenotype reprograms glutamatergic network in receptor tyrosine kinase gene-mutated glioblastoma	48
Response to the letter by de Boer et al. (2022)	48
Comparison of transcriptome profiles between medulloblastoma primary and recurrent tumors uncovers novel variance effects in relapses	47
Low-intensity open-field blast exposure effects on neurovascular unit ultrastructure in mice	45
Decoding of the surfaceome and endocytome in primary glioblastoma cells identifies potential target antigens in the hypoxic tumor niche	44
Integration of single-nuclei RNA-sequencing, spatial transcriptomics and histochemistry defines the complex microenvironment of NF1-associated plexiform neurofibromas	43
Loss of Sarm1 reduces retinal ganglion cell loss in chronic glaucoma	41
Clinicopathologic features of two unrelated autopsied patients with Charcot-Marie-Tooth disease carrying MFN2 gene mutation	41
A novel BRAF::PTPRN2 fusion in meningioma: a case report	40
Intravitreal MPTP drives retinal ganglion cell loss with oral nicotinamide treatment providing robust neuroprotection	40
Disease and brain region specific immune response profiles in neurodegenerative diseases with pure and mixed protein pathologies	40
Distinct tumor-TAM interactions in IDH-stratified glioma microenvironments unveiled by single-cell and spatial transcriptomics	39
A pathogenic mutation in the ALS/FTD gene VCP induces mitochondrial hypermetabolism by modulating the permeability transition pore	39
Real-world experience with circulating tumor DNA in cerebrospinal fluid from patients with central nervous system tumors	39
Molecular pathology, developmental changes and synaptic dysfunction in (pre-) symptomatic human C9ORF72-ALS/FTD cerebral organoids	39
Early biomarkers in the presymptomatic phase of cognitive impairment: changes in the endocannabinoidome and serotonergic pathways in Alzheimer's-prone mice after mTBI	38
Prion strains associated with iatrogenic CJD in French and UK human growth hormone recipients	38
Efficacy of BRAF/MEK-inhibitor therapy for epithelioid glioblastoma with a novel BRAFV600 mutation	38
Correction to: Alzheimer’s disease tau is a prominent pathology in LRRK2 Parkinson’s disease	38
Importance of extracellular vesicle secretion at the blood–cerebrospinal fluid interface in the pathogenesis of Alzheimer’s disease	37
Tuberous sclerosis complex is a novel, amyloid-independent tauopathy associated with elevated phosphorylated 3R/4R tau aggregation	36
Heparanase overexpression impedes perivascular clearance of amyloid-β from murine brain: relevance to Alzheimer’s disease	35
Increased unsaturated lipids underlie lipid peroxidation in synucleinopathy brain	35
Ultrasensitive tau biosensor cells detect no seeding in Alzheimer’s disease CSF	34
Alterations in iron content, iron-regulatory proteins and behaviour without tau pathology at one year following repetitive mild traumatic brain injury	34
Spatial progression and molecular heterogeneity of IDH-mutant glioblastoma determined by DNA methylation-based mapping	34
Transmission of amyloid-beta and tau pathologies is associated with cognitive impairments in a primate	34
White matter injury but not germinal matrix hemorrhage induces elevated osteopontin expression in human preterm brains	34
NRF2/ARE mediated antioxidant response to glaucoma: role of glia and retinal ganglion cells	34
Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice	33
Bruton’s tyrosine kinase inhibition reduces disease severity in a model of secondary progressive autoimmune demyelination	33
The inflammatory pathology of dysferlinopathy is distinct from calpainopathy, Becker muscular dystrophy, and inflammatory myopathies	33
Antemortem detection of Parkinson’s disease pathology in peripheral biopsies using artificial intelligence	33
Impaired SorLA maturation and trafficking as a new mechanism for SORL1 missense variants in Alzheimer disease	32
The neuropathological landscape of small vessel disease and Lewy pathology in a cohort of Hispanic and non-Hispanic White decedents with Alzheimer disease	32
Downstream effects of polypathology on neurodegeneration of medial temporal lobe subregions	32
Multi-platform quantitation of alpha-synuclein human brain proteoforms suggests disease-specific biochemical profiles of synucleinopathies	32
Tau seeding in cases of multiple sclerosis	32
A recurrent RYR1 mutation associated with early-onset hypotonia and benign disease course	32
Machine learning quantification of Amyloid-β deposits in the temporal lobe of 131 brain bank cases	31
The locus coeruleus input to the rostral ventromedial medulla mediates stress-induced colorectal visceral pain	31
TwinF interface inhibitor FP802 prevents retinal ganglion cell loss in a mouse model of amyotrophic lateral sclerosis	31
The polyG diseases: a new disease entity	31
Different MAPT haplotypes influence expression of total MAPT in postmortem brain tissue	31
The contribution of DNA methylation to the (dys)function of oligodendroglia in neurodegeneration	31
Human tau-overexpressing mice recapitulate brainstem involvement and neuropsychiatric features of early Alzheimer’s disease	31
Liver X receptor-agonist treatment rescues degeneration in a Drosophila model of hereditary spastic paraplegia	30
Dual-probe fluorescence spectroscopy for sensitive quantitation of Alzheimer’s amyloid pathology	30
Unsupervised machine learning identifies distinct ALS molecular subtypes in post-mortem motor cortex and blood expression data	30
Clinicopathological and molecular characterization of a case classified by DNA‑methylation profiling as “CNS embryonal tumor with BRD4–LEUTX fusion”	30

Oligodendrocyte lineage is severely affected in human alcohol-exposed foetuses	30
Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer’s-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative microglia	30
Widespread retina and optic nerve neuroinflammation in enucleated eyes from glaucoma patients	29
MiR-212-3p functions as a tumor suppressor gene in group 3 medulloblastoma via targeting nuclear factor I/B (NFIB)	29
Correction: Host genetics and gut microbiota influence lipid metabolism and inflammation: potential implications for ALS pathophysiology in SOD1G93A mice	29
Spatiotemporal perturbations of the plasminogen activation system in a rat model of acute organophosphate intoxication	29
The degree of astrocyte activation is predictive of the incubation time to prion disease	28
3-Dimensional morphological characterization of neuroretinal microglia in Alzheimer’s disease via machine learning	28
Repetitive mild traumatic brain injury in mice triggers a slowly developing cascade of long-term and persistent behavioral deficits and pathological changes	27
Trem2-deficiency aggravates and accelerates age-related myelin degeneration	27
Neuropathology-based approach reveals novel Alzheimer's Disease genes and highlights female-specific pathways and causal links to disrupted lipid metabolism: insights into a vicious cycle	27
A novel patient-derived meningioma spheroid model as a tool to study and treat epithelial-to-mesenchymal transition (EMT) in meningiomas	26
Blood-spinal cord barrier leakage is independent of motor neuron pathology in ALS	26
Disseminated diffuse midline gliomas, H3K27-altered mimicking diffuse leptomeningeal glioneuronal tumors: a diagnostical challenge!	26
Development and characterization of novel anti-acetylated tau monoclonal antibodies to probe pathogenic tau species in Alzheimer’s disease	26
Correction to: Integrated genomic analysis reveals actionable targets in pediatric spinal cord low-grade gliomas	26
A toxic gain-of-function mechanism in C9orf72 ALS impairs the autophagy-lysosome pathway in neurons	26
BDNF-dependent modulation of axonal transport is selectively impaired in ALS	26
Protein farnesylation is upregulated in Alzheimer’s human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer’s model mice	26
Correction: Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer’s disease	26
Exogenous interleukin 33 enhances the brain’s lymphatic drainage and toxic protein clearance in acute traumatic brain injury mice	25
Three dimensional evaluation of cerebrovascular density and branching in chronic traumatic encephalopathy	25
TDP-43 pathology is sufficient to drive axon initial segment plasticity and hyperexcitability of spinal motoneurones in vivo in the TDP43-ΔNLS model of Amyotrophic Lateral Sclerosis	25
Single-cell spatial proteomic imaging for human neuropathology	25
Mical modulates Tau toxicity via cysteine oxidation in vivo	25
Late chronic local inflammation, synaptic alterations, vascular remodeling and arteriovenous malformations in the brains of male rats exposed to repetitive low-level blast overpressures	25
Axonal autophagic vesicle transport in the rat optic nerve in vivo under normal conditions and during acute axonal degeneration	24
C5aR1 antagonism alters microglial polarization and mitigates disease progression in a mouse model of Alzheimer’s disease	24
The pathogenic role of c-Kit+ mast cells in the spinal motor neuron-vascular niche in ALS	24
Targeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivo	24
Hyperspectral retinal imaging in Alzheimer’s disease and age-related macular degeneration: a review	24
Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis	23
The genomic alterations in glioblastoma influence the levels of CSF metabolites	23
Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies	23
Tissue-specific and repeat length-dependent somatic instability of the X-linked dystonia parkinsonism-associated CCCTCT repeat	23
Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer’s disease	23
Dissection of transcriptomic and epigenetic heterogeneity of grade 4 gliomas: implications for prognosis	23
Supratentorial non-RELA, ZFTA-fused ependymomas: a comprehensive phenotype genotype correlation highlighting the number of zinc fingers in ZFTA-NCOA1/2 fusions	22
Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau	22
Predictors of cognitive impairment in primary age-related tauopathy: an autopsy study	22
Personalising glioblastoma medicine: explant organoid applications, challenges and future perspectives	22
Asymmetric dysregulation of glutamate dynamics across the synaptic cleft in a mouse model of Alzheimer’s disease	22
Human post-mortem organotypic brain slice cultures: a tool to study pathomechanisms and test therapies	22
Interpretable deep learning of myelin histopathology in age-related cognitive impairment	22
Right temporal variant frontotemporal dementia is pathologically heterogeneous: a case-series and a systematic review	22
Deep histopathology genotype–phenotype analysis of focal cortical dysplasia type II differentiates between the GATOR1-altered autophagocytic subtype IIa and MTOR-altered migration deficient subtype II	22
Differential protein expression in the hippocampi of resilient individuals identified by digital spatial profiling	22
Early onset senescence and cognitive impairment in a murine model of repeated mTBI	21
Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease	21
Differential effects of mutations of POPDC proteins on heteromeric interaction and membrane trafficking	21
Molecular and clinicopathologic characteristics of CNS embryonal tumors with BRD4::LEUTX fusion	21
DNA methylation-based age acceleration observed in IDH wild-type glioblastoma is associated with better outcome—including in elderly patients	21
Tau seed amplification assay reveals relationship between seeding and pathological forms of tau in Alzheimer’s disease brain	21
Correction to: High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson’s disease	21
SARS-Cov-2 infection and neuropathological findings: a report of 18 cases and review of the literature	21
Immediate induction of varicosities by transverse compression but not uniaxial stretch in axon mechanosensation	21
An integrated genetic analysis of epileptogenic brain malformed lesions	20
PRC2 disruption in cerebellar progenitors produces cerebellar hypoplasia and aberrant myoid differentiation without blocking medulloblastoma growth	20
Correction to: Mical modulates Tau toxicity via cysteine oxidation in vivo	20
Sporadic Creutzfeldt-Jakob disease VM1: phenotypic and molecular characterization of a novel subtype of human prion disease	20
Temporal patterns of microglial activation in white matter following experimental mild traumatic brain injury: a systematic literature review	20
Wolfram syndrome 1b mutation suppresses Mauthner-cell axon regeneration via ER stress signal pathway	20
The α-dystrobrevins play a key role in maintaining the structure and function of the extracellular matrix–significance for protein elimination failure arteriopathies	20
Ballooned neurons in semi-recent severe traumatic brain injury	20
Loss of glucocorticoid receptor phosphorylation contributes to cognitive and neurocentric damages of the amyloid-β pathway	20
ER stress induced immunopathology involving complement in CADASIL: implications for therapeutics	20
Abcd1 deficiency accelerates cuprizone-induced oligodendrocyte loss and axonopathy in a demyelinating mouse model of X-linked adrenoleukodystrophy	19
Ex vivo MRI atlas of the human medial temporal lobe: characterizing neurodegeneration due to tau pathology	19
Correction: Clinical implications of DNA methylation-based integrated classification of histologically defined grade 2 meningiomas	19
Molecular reclassification reveals low prevalence of germline predisposition in children with ependymoma	19
Distribution of Lewy-related pathology in the brain, spinal cord, and periphery: the population-based Vantaa 85 + study	19
The oncogenic circular RNA circ_63706 is a potential therapeutic target in sonic hedgehog-subtype childhood medulloblastomas	19
Spinocerebellar ataxia type 17-digenic TBP/STUB1 disease: neuropathologic features of an autopsied patient	19
X-linked SBMA model mice display relevant non-neurological phenotypes and their expression of mutant androgen receptor protein in motor neurons is not required for neuromuscular disease	19
Evidence of cerebellar TDP-43 loss of function in FTLD-TDP	18
BCOR::CREBBP fusion in malignant neuroepithelial tumor of CNS expands the spectrum of methylation class CNS tumor with BCOR/BCOR(L1)-fusion	18
Increase in wasteosomes (corpora amylacea) in frontotemporal lobar degeneration with specific detection of tau, TDP-43 and FUS pathology	18
Differential vulnerability of the dentate gyrus to tauopathies in dementias	18
Hippocampal capillary pericytes in post-stroke and vascular dementias and Alzheimer’s disease and experimental chronic cerebral hypoperfusion	18
Effects of local reduction of endogenous α-synuclein using antisense oligonucleotides on the fibril-induced propagation of pathology through the neural network in wild-type mice	18

Quantitative multiplex immunohistochemistry with colorimetric staining (QUIVER) may still benefit from MILAN	18
Ibrutinib disrupts blood-tumor barrier integrity and prolongs survival in rodent glioma model	18
MYC overexpression and SMARCA4 loss cooperate to drive medulloblastoma formation in mice	18
Therapeutic potential of targeting Nrf2 by panobinostat in pituitary neuroendocrine tumors	18
The role of plasminogen activator inhibitor-2 in pneumococcal meningitis	18
CNS tumor with CREBBP::BCORL1 Fusion and pathogenic mutations in BCOR and CREBBP: expanding the spectrum of BCOR-altered tumors	17
Frontal lobe microglia, neurodegenerative protein accumulation, and cognitive function in people with HIV	17
Homozygous CDKN2A/B deletions in low- and high-grade glioma: a meta-analysis of individual patient data and predictive values of p16 immunohistochemistry testing	17
Neuroradiological, genetic and clinical characteristics of histone H3 K27-mutant diffuse midline gliomas in the Kansai Molecular Diagnosis Network for CNS Tumors (Kansai Network): multicenter retrospe	17
Torpor induces reversible tau hyperphosphorylation and accumulation in mice expressing human tau	17
Retinal cytoarchitecture is preserved in an organotypic perfused human and porcine eye model	17
Neuromuscular junction pathology is correlated with differential motor unit vulnerability in spinal and bulbar muscular atrophy	17
VISTA regulates microglia homeostasis and myelin phagocytosis, and is associated with MS lesion pathology	17
The specific DNA methylation landscape in focal cortical dysplasia ILAE type 3D	17
Correction: SNCA genetic lowering reveals differential cognitive function of alpha-synuclein dependent on sex	17
The distribution and density of Huntingtin inclusions across the Huntington disease neocortex: regional correlations with Huntingtin repeat expansion independent of pathologic grade	17
Pure argyrophilic grain disease revisited: independent effects on limbic, neocortical, and striato-pallido-nigral degeneration and the development of dementia in a series with a low to moderate Braak	17
Publisher Correction: Ganglioglioma deep transcriptomics reveals primitive neuroectoderm neural precursor‑like population	17
SNCA genetic lowering reveals differential cognitive function of alpha-synuclein dependent on sex	17
Alcohol-induced damage to the fimbria/fornix reduces hippocampal-prefrontal cortex connection during early abstinence	16
Urinary D-asparagine level is decreased by the presence of glioblastoma	16
Metabolic and transcriptomic profiles of glioblastoma invasion revealed by comparisons between patients and corresponding orthotopic xenografts in mice	16
Reduced T-cell densities in cranial nerves of patients who died with SARS-CoV-2 infection	16
Neurofibromatosis type 1-dependent alterations in mouse microglia function are not cell-intrinsic	16
Germline loss-of-function variant in the E3 ubiquitin ligase TRAF2 in a young adult patient with medulloblastoma: a case report	16
Spontaneous intracerebral haemorrhage associated with early-onset cerebral amyloid angiopathy and Alzheimer’s disease neuropathological changes five decades after cadaveric dura mater graft	16
High-resolution transcriptomics informs glial pathology in human temporal lobe epilepsy	16
Correction: Neuroradiological, genetic and clinical characteristics of histone H3 K27-mutant diffuse midline gliomas in the Kansai Molecular Diagnosis Network for CNS Tumors (Kansai Network): multicen	16
Acute axon damage and demyelination are mitigated by 4-aminopyridine (4-AP) therapy after experimental traumatic brain injury	15
Cranial radiation disrupts dopaminergic signaling and connectivity in the mammalian brain	15
Diffuse glioneuronal tumor with oligodendroglioma-like features and nuclear clusters (DGONC), new name and new problems: an illustration of one case with atypical morphology and biology	15
Sarcomatous transformation of IDH-mutant astrocytoma matching to methylation class oligosarcoma following embolization, a case report	15
Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion	15
A neuropathologic feature of brain aging: multi-lumen vascular profiles	15
A microdeletion event at 19q13.43 in IDH-mutant astrocytomas is strongly correlated with MYC overexpression	15
Targeting the TDP-43 low complexity domain blocks spreading of pathology in a mouse model of ALS/FTD	15
Amyloid precursor protein elevates fusion of promyelocytic leukemia nuclear bodies in human hippocampal areas with high plaque load	15
A sellar presentation of a WNT-activated embryonal tumor: further evidence of an ectopic medulloblastoma	15
A minimally invasive biomarker for sensitive and accurate diagnosis of Parkinson’s disease	15
LATE-NC aggravates GVD-mediated necroptosis in Alzheimer’s disease	14
ROS-regulated SUR1-TRPM4 drives persistent activation of NLRP3 inflammasome in microglia after whole-brain radiation	14
Disruption of mitochondrial homeostasis and permeability transition pore opening in OPA1 iPSC-derived retinal ganglion cells	14
Müller cell degeneration and microglial dysfunction in the Alzheimer’s retina	14
Correction to: Higher angiotensin‑converting enzyme 2 (ACE2) levels in the brain of individuals with Alzheimer’s disease	14
Chromogen-based double immunohistochemical detection of mitochondrial respiratory chain deficiencies in human brain tissue	14
The dural angioleiomyoma harbors frequent GJA4 mutation and a distinct DNA methylation profile	14
Publisher Correction: Exploring the significance of caspase-cleaved tau in tauopathies and as a complementary pathology to phospho-tau in Alzheimer’s disease: implications for biomarker development an	14
The tumour microenvironment of pilocytic astrocytoma evolves over time via enrichment for microglia	14
The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects	14
Clinical and molecular characteristics and long-term outcomes of pediatric intracranial meningiomas: a comprehensive analysis from a single neurosurgical center	14
EMP3 sustains oncogenic EGFR/CDK2 signaling by restricting receptor degradation in glioblastoma	14
Genetic inactivation of SARM1 axon degeneration pathway improves outcome trajectory after experimental traumatic brain injury based on pathological, radiological, and functional measures	14
Clinical and functional characterization of a long survivor congenital titinopathy patient with a novel metatranscript-only titin variant	14
AQP4 labels a subpopulation of white matter-dependent glial radial cells affected by pediatric hydrocephalus, and its expression increased in glial microvesicles released to the cerebrospinal fluid in	14
X-linked ubiquitin-specific peptidase 11 (USP11) increases susceptibility to Cushing’s disease in women	14
White matter damage due to vascular, tau, and TDP-43 pathologies and its relevance to cognition	14
Autophagy is affected in patients with hypokalemic periodic paralysis: an involvement in vacuolar myopathy?	14
NF2 and ZFTA evaluation in the diagnostic algorithm of pediatric posterior fossa ependymoma with H3K27ME3 retained expression	14