OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Intensive Care is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Long-term recovery of sensorimotor functions and prediction of participation in survivors of critical illness: a prospective cohort study	230
Mechanisms maintaining right ventricular contractility-to-pulmonary arterial elastance ratio in VA ECMO: a retrospective animal data analysis of RV–PA coupling	128
Diagnostic accuracy of tests for assessing readiness for liberation from mechanical ventilation in adults: an overview of reviews	84
Nutritional therapy for the prevention of post-intensive care syndrome	73
The revised recommendation for administering vitamin C in septic patients: the Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020	71
Acute lung injury and post-cardiac arrest syndrome: a narrative review	60
Dose–response relationship between transfusion and the incidence of infection in critically ill patients: a systematic review and dose–response meta-analysis	54
Long-term health outcomes of COVID-19 in ICU- and non-ICU-treated patients up to 2 years after hospitalization: a longitudinal cohort study (CO-FLOW)	47
Post-resuscitation diastolic blood pressure is a prognostic factor for outcomes of cardiac arrest patients: a multicenter retrospective registry-based analysis	37
Which factors are associated with acquired weakness in the ICU? An overview of systematic reviews and meta-analyses	34
Role of the interstitium during septic shock: a key to the understanding of fluid dynamics?	33
Extracorporeal membrane oxygenation for COVID-19-related acute respiratory distress syndrome: a narrative review	32
Trends in massive transfusion practice for trauma in Japan from 2011 to 2020: a nationwide inpatient database study	32
Current corticosteroid therapeutic strategy for community-acquired pneumonia in adults: indications, dosage, and timing	32
External validation and comparative performance of the SLANT score for neuroprognostication in out-of-hospital cardiac arrest survivors undergoing targeted temperature management: insights from an Asi	32
Effects of a multicomponent sleep enhancement protocol on delirium incidence in elderly critically ill surgical patients: a randomized controlled trial	31
Analysis of urinary C–C motif chemokine ligand 14 (CCL14) and first-generation urinary biomarkers for predicting renal recovery from acute kidney injury: a prospective exploratory study	31
Calculated left ventricular outflow tract diameter for critically ill patients	31
The pathophysiology, diagnosis, and management of sepsis-associated disseminated intravascular coagulation	28
Management of endothelial dysfunction in septic shock: role of albumin administration	26
Early systemic insults following severe sepsis-associated encephalopathy of critically ill patients: association with mortality and awakening—an analysis of the OUTCOMEREA database	24
Response to “Predicting high-flow nasal cannula failure: beyond static indices toward dynamic physiologic assessment”	24
Classifying diarrhea in critically ill patients through various criteria: a cohort study	24
Fentanyl as an induction agent for tracheal intubation in critically ill patients: a systematic review and meta-analysis	24
Clinical effectiveness of tigecycline in combination therapy against nosocomial pneumonia caused by CR-GNB in intensive care units: a retrospective multi-centre observational study	24

Acute pulmonary edema after subarachnoid hemorrhage: risk factors and comorbidities—an analysis of a nationwide database from the United States	23
Discontinuation of the development of remimazolam for ICU sedation in Japan: background and rationale	23
Circulating and urinary microRNAs profile for predicting renal recovery from severe acute kidney injury	22
The optimal glycemic target in critically ill patients: an updated network meta-analysis	21
Extracorporeal membrane oxygenation support for tropical infections: a scoping review	20
The hemodynamics of tracheal intubation in critically ill patients: a narrative review	20
Echocardiographic phenotypes in sepsis: identifying subgroups using latent profile analysis	20
One-year outcomes in sepsis: a prospective multicenter cohort study in Japan	20
Prognostic nutritional index as a predictive marker for acute kidney injury in adult critical illness population: a systematic review and diagnostic test accuracy meta-analysis	19
Thermal intervention improves pulse oximetry accuracy in critically ill patients with low perfusion: a quasi-experimental study	19
Low-flow time and outcomes in hypothermic cardiac arrest patients treated with extracorporeal cardiopulmonary resuscitation: a secondary analysis of a multi-center retrospective cohort study	19
Long-term prognostic significance of gasping in out-of-hospital cardiac arrest patients undergoing extracorporeal cardiopulmonary resuscitation: a post hoc analysis of a multi-center prospective cohor	18
Descriptive statistics and risk factor analysis of children with community-acquired septic shock	17
Post-intensive care syndrome follow-up system after hospital discharge: a narrative review	16
UNLOADERS-PVAD Weaning Score: predicting post-weaning adverse events in cardiogenic shock patients supported by microaxial flow pump	16
Optimizing infection management after cardiac arrest: addressing diagnostic uncertainty and therapeutic dilemmas—a narrative review	16
Recent advances in cardiorespiratory monitoring in acute respiratory distress syndrome patients	16
Using laxative to recover intestinal function could improve the survival outcome for patients with cardiac arrest: a retrospective cohort study from MIMIC-IV database	16
Construction of a predictive model and prognosis of left ventricular systolic dysfunction in patients with sepsis based on the diagnosis using left ventricular global longitudinal strain	15
Correction: One-year outcomes in sepsis: a prospective multicenter cohort study in Japan	15
Association between antithrombin levels and prognosis in patients with sepsis: a retrospective cohort study based on the MIMIC-IV and MIMIC-III databases	15
Exploring METRNL as a novel biomarker in sepsis: diagnostic potential and secretion mechanism	15
Impacts of three inspiratory muscle training programs on inspiratory muscles strength and endurance among intubated and mechanically ventilated patients with difficult weaning: a multicentre randomise	15
Hemorrhage and thrombosis in COVID-19-patients supported with extracorporeal membrane oxygenation: an international study based on the COVID-19 critical care consortium	14
Strategies for discontinuing vasopressin and norepinephrine during the recovery phase of shock: a single-center retrospective study	14
Intensive care unit versus high-dependency care unit admission on mortality in patients with septic shock: a retrospective cohort study using Japanese claims data	14
Development and validation of a nomogram to predict the risk of sepsis-associated encephalopathy for septic patients in PICU: a multicenter retrospective cohort study	14
Autophagy and autophagic cell death in sepsis: friend or foe?	13
PICS-SES postintensive care syndrome and socioeconomic status	13
The method to identify invasive mechanical ventilation with Japanese claim data	13
Impact of the COVID-19 pandemic on critical care utilization in Japan: a nationwide inpatient database study	13
Changes in gene expression in healthcare workers during night shifts: implications for immune response and health risks	13
Efficacy of permissive underfeeding for critically ill patients: an updated systematic review and trial sequential meta-analysis	13
Longitudinal proteomic analysis of pathophysiology in plasma and bronchoalveolar lavage fluid of patients with ARDS	13
Prone positioning in ARDS patients supported with VV ECMO, what we should explore?	13
Erythropoietin as a critical prognostic indicator in ICU patients with sepsis: a prospective observational study	12
Prediction of high-flow nasal cannula failure in critically ill patients: a narrative review	12
Effects of two ventilator-weaning methods on lung volume and ventilation distribution by electrical impedance tomography in post-cardiac surgery patients: a prospective cohort study	12
Association between the timing of ICU admission and mortality in patients with hospital-onset sepsis: a nationwide prospective cohort study	12
Prolonged use of neuromuscular blocking agents is associated with increased long-term mortality in mechanically ventilated medical ICU patients: a retrospective cohort study	12
Re-evaluating albumin use in traumatic brain injury	11
Effectiveness of systemic thrombolysis on clinical outcomes in high-risk pulmonary embolism patients with venoarterial extracorporeal membrane oxygenation: a nationwide inpatient database study	11
Rethinking diuretic use in acute kidney injury: effective prevention or false hope?	11
Association of multiple sclerosis with mortality in sepsis: a population-level analysis	11
Prognostic significance of delirium subtypes in critically ill medical and surgical patients: a secondary analysis of a prospective multicenter study	11
Evaluating the diagnostic performance of adult sepsis event criteria in the emergency department: impact of including isolated serum lactate elevations	11
National cost of intensive care in Japan from 2018 to 2022	11
Association between the triglyceride–glucose index and the risk of acute kidney injury in critically ill patients with acute pancreatitis: a retrospective study	11
The cardioprotective and anti-inflammatory effect of inhaled nitric oxide during Fontan surgery in patients with single ventricle congenital heart defects: a prospective randomized study	11
Onset timing and duration of augmented renal clearance in a mixed intensive care unit	11

Hospital and regional variations in intensive care unit admission for patients with invasive mechanical ventilation	10
Association between organ dysfunction during ICU stay and post-intensive care syndrome at 1 year after ICU discharge: a prospective cohort study	10
Occurrence of pendelluft during ventilator weaning with T piece correlated with increased mortality in difficult-to-wean patients	10
A pilot multicenter randomized controlled trial on individualized blood pressure targets versus standard care among critically ill patients with shock	9
Prehospital tranexamic acid for trauma victims	9
Alteration of circulating redox balance in coronavirus disease-19-induced acute respiratory distress syndrome	9
Combination of Cv-aCO2/Ca-vO2 and Pv-aCO2 as markers of resuscitation or microcirculation in patients with septic shock: a pilot study	9
Association of continuous renal replacement therapy downtime with fluid balance gap and clinical outcomes: a retrospective cohort analysis utilizing EHR and machine data	9
Prognostic value of oxygen saturation index trajectory phenotypes on ICU mortality in mechanically ventilated patients: a multi-database retrospective cohort study	9
Remimazolam in pediatric sedation and anesthesia: current perspectives and clinical considerations	8
Different definitions of feeding intolerance and their associations with outcomes of critically ill adults receiving enteral nutrition: a systematic review and meta-analysis	8
Two-year trajectory of functional recovery and quality of life in post-intensive care syndrome: a multicenter prospective observational study on mechanically ventilated patients with coronavirus disea	8
Efficacy of therapeutic drug monitoring-based antibiotic regimen in critically ill patients: a systematic review and meta-analysis of randomized controlled trials	8
Inhaled nitric oxide for acute respiratory distress syndrome in adults: a systematic review and meta-analysis	8
Author’s response to the letter “Japanese clinical practice guidelines for rehabilitation in critically ill patients 2023 (J-ReCIP 2023)”	8
Computed tomography in ARDS, from morphological insights to AI-powered multi-modal analysis: a narrative review	8
Extracorporeal cardiopulmonary resuscitation with temperature management could improve the neurological outcomes of out-of-hospital cardiac arrest: a retrospective analysis of a nationwide multicenter	8
Recovery of consciousness after acute brain injury: a narrative review	7
Increasing plasma calprotectin (S100A8/A9) is associated with 12-month mortality and unfavourable functional outcome in critically ill COVID-19 patients	7
Fundamental concepts and the latest evidence for esophageal pressure monitoring	7
Temporal trends of medical cost and cost-effectiveness in sepsis patients: a Japanese nationwide medical claims database	7
Short- and long-term outcomes of elderly patients with acute kidney injury to acute kidney disease	7
Impact of sympathetic hyperactivity induced by brain microglial activation on organ damage in sepsis with chronic kidney disease	7
Hemoglobin in cardiogenic shock: the lower, the poorer survival	7
Low apolipoprotein A-II levels causally contribute to increased mortality in septic shock	7
Visualizing the dynamic mechanical power and time burden of mechanical ventilation patients: an analysis of the MIMIC-IV database	7
Optimal timing for assessing post-intensive care syndrome in clinical research: a scoping review and expert survey	7
Mortality analysis among sepsis patients in and out of intensive care units using the Japanese nationwide medical claims database: a study by the Japan Sepsis Alliance study group	6
Effect of early intubation on patient-centered outcomes in urosepsis: a retrospective multicenter cohort study	6
Prevention and management of critical care complications in cardiogenic shock: a narrative review	6
Respiratory drive: a journey from health to disease	6
PEEP-AKI-COVID ICU: Effect of positive end-expiratory pressure on acute kidney injury development in patients with COVID-19-associated acute respiratory distress syndrome: an ancillary analysis of the	6
Granulomonocytapheresis for chronic inflammatory diseases and sepsis	6
Long-term prevalence of PTSD symptom in family members of severe COVID-19 patients: a serial follow-up study extending to 18 months after ICU discharge	6
Pharmacological profiles and mechanism of action of remimazolam for ICU sedation	6
Exploring the scope of inspiratory muscle training in difficult weaning: reflections on the multicentre RCT	6
Comparison of balanced and unbalanced crystalloids as resuscitation fluid in patients treated for cardiogenic shock	6
Limitation of life sustaining measures in neurocritical care: sex, timing, and advance directive	5
Japanese Clinical Practice Guidelines for Rehabilitation in Critically Ill Patients 2023 (J-ReCIP 2023)	5
Safety and efficacy of remimazolam in critical illness	5
Mechanical ventilation in patients with cardiogenic pulmonary edema: a sub-analysis of the LUNG SAFE study	5
Ability of the respiratory ECMO survival prediction (RESP) score to predict survival for patients with COVID-19 ARDS and non-COVID-19 ARDS: a single-center retrospective study	5
Association between red blood cell distribution width and 30-day mortality in critically ill septic patients: a propensity score-matched study	5
Sepsis-related coagulopathy treatment based on the disseminated intravascular coagulation diagnostic criteria: a post-hoc analysis of a prospective multicenter observational study	5
Outcomes of combined carbazochrome sodium sulfonate plus tranexamic acid therapy versus tranexamic acid monotherapy in traumatic brain injury: a retrospective cohort study in Japan	5
Critical evaluation of “Exploratory characterization of dynamic soluble programmed death-ligand 1 trajectories and their association with mortality in critical COVID-19”	5
Predictors of and hospital-level variation in intensive care unit readmissions in Japan: a nationwide inpatient database study	5
Impact of prehospital antibiotic therapy differs depending on septic shock origin	5
Respiratory physiotherapy for critically ill children: concern regarding a recommendation	5
Normal saline versus Ringer’s solution and critical-illness mortality in acute pancreatitis: a nationwide inpatient database study	5
Long-term outcome of COVID-19 patients treated with helmet noninvasive ventilation vs. high-flow nasal oxygen: a randomized trial	5
Lacosamide dosing in patients receiving continuous renal replacement therapy	4
Association between initial intravenous fluid volume and the composite outcome of hemodialysis dependence at discharge or in-hospital mortality in inpatients with rhabdomyolysis	4
Clinical utility of diaphragmatic ultrasound for mechanical ventilator liberation in adults: a systematic review and meta-analysis	4
Effects of normal saline versus lactated Ringer’s solution on organ function and inflammatory responses to heatstroke in rats	4
Chest CT findings in severe acute respiratory distress syndrome requiring V-V ECMO: J-CARVE registry	4
The time cost of physiologically ineffective intravenous fluids in the emergency department: an observational pilot study employing wearable Doppler ultrasound	4
Association between histological diaphragm atrophy and ultrasound diaphragm expiratory thickness in ventilated patients	4
Height status matters for risk of mortality in critically ill children	4
High driving pressure ventilation induces pulmonary hypertension in a rabbit model of acute lung injury	4
Unit-to-unit transfer due to shortage of intensive care beds in Sweden 2015–2019 was associated with a lower risk of death but a longer intensive care stay compared to no transfer: a registry study	4
Concerns with the revised Japanese recommendation for administering vitamin C to septic patients	4