OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Intensive Care is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Mechanisms maintaining right ventricular contractility-to-pulmonary arterial elastance ratio in VA ECMO: a retrospective animal data analysis of RV–PA coupling	150
Nutritional therapy for the prevention of post-intensive care syndrome	122
The revised recommendation for administering vitamin C in septic patients: the Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020	66
Post-resuscitation diastolic blood pressure is a prognostic factor for outcomes of cardiac arrest patients: a multicenter retrospective registry-based analysis	50
Which factors are associated with acquired weakness in the ICU? An overview of systematic reviews and meta-analyses	40
Role of the interstitium during septic shock: a key to the understanding of fluid dynamics?	36
Brain death: a clinical overview	35
Long-term health outcomes of COVID-19 in ICU- and non-ICU-treated patients up to 2 years after hospitalization: a longitudinal cohort study (CO-FLOW)	34
Acute lung injury and post-cardiac arrest syndrome: a narrative review	32
Calculated left ventricular outflow tract diameter for critically ill patients	31
Trends in massive transfusion practice for trauma in Japan from 2011 to 2020: a nationwide inpatient database study	30
External validation and comparative performance of the SLANT score for neuroprognostication in out-of-hospital cardiac arrest survivors undergoing targeted temperature management: insights from an Asi	28
Current corticosteroid therapeutic strategy for community-acquired pneumonia in adults: indications, dosage, and timing	27
The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020)	26
Clinical significance of lactate clearance in patients with cardiogenic shock: results from the RESCUE registry	26
Association between intensive care unit admission of a patient and mental disorders in the spouse: a retrospective matched-pair cohort study	26
Analysis of urinary C–C motif chemokine ligand 14 (CCL14) and first-generation urinary biomarkers for predicting renal recovery from acute kidney injury: a prospective exploratory study	25
The pathophysiology, diagnosis, and management of sepsis-associated disseminated intravascular coagulation	23
Clinical effectiveness of tigecycline in combination therapy against nosocomial pneumonia caused by CR-GNB in intensive care units: a retrospective multi-centre observational study	22
Extracorporeal membrane oxygenation for COVID-19-related acute respiratory distress syndrome: a narrative review	22
Early systemic insults following severe sepsis-associated encephalopathy of critically ill patients: association with mortality and awakening—an analysis of the OUTCOMEREA database	20
Circulating dipeptidyl peptidase 3 on intensive care unit admission is a predictor of organ dysfunction and mortality	20
Ultraprotective versus apneic ventilation in acute respiratory distress syndrome patients with extracorporeal membrane oxygenation: a physiological study	20
The optimal glycemic target in critically ill patients: an updated network meta-analysis	18
New avenues of sepsis research: obtaining perspective by analyzing and comparing SSCG 2021 and J-SSCG 2020	18

Circulating and urinary microRNAs profile for predicting renal recovery from severe acute kidney injury	18
Recommendations for long-term outcomes in sepsis and septic shock: a comparison between Japanese and international guidelines	18
One-year outcomes in sepsis: a prospective multicenter cohort study in Japan	17
Acute pulmonary edema after subarachnoid hemorrhage: risk factors and comorbidities—an analysis of a nationwide database from the United States	17
Descriptive statistics and risk factor analysis of children with community-acquired septic shock	16
Long-term prognostic significance of gasping in out-of-hospital cardiac arrest patients undergoing extracorporeal cardiopulmonary resuscitation: a post hoc analysis of a multi-center prospective cohor	16
Current status of palliative care delivery and self-reported practice in ICUs in Japan: a nationwide cross-sectional survey of physician directors	15
Paradox of trimethylamine-N-oxide, the impact of malnutrition on microbiota-derived metabolites and septic patients	15
Low-flow time and outcomes in hypothermic cardiac arrest patients treated with extracorporeal cardiopulmonary resuscitation: a secondary analysis of a multi-center retrospective cohort study	15
Prognostic nutritional index as a predictive marker for acute kidney injury in adult critical illness population: a systematic review and diagnostic test accuracy meta-analysis	14
The Ichikado CT score as a prognostic tool for coronavirus disease 2019 pneumonia: a retrospective cohort study	14
Post-intensive care syndrome follow-up system after hospital discharge: a narrative review	14
Hemorrhage and thrombosis in COVID-19-patients supported with extracorporeal membrane oxygenation: an international study based on the COVID-19 critical care consortium	14
Recent advances in cardiorespiratory monitoring in acute respiratory distress syndrome patients	14
Impacts of three inspiratory muscle training programs on inspiratory muscles strength and endurance among intubated and mechanically ventilated patients with difficult weaning: a multicentre randomise	14
Correction: One-year outcomes in sepsis: a prospective multicenter cohort study in Japan	13
Exploring METRNL as a novel biomarker in sepsis: diagnostic potential and secretion mechanism	13
Intensive care unit versus high-dependency care unit admission on mortality in patients with septic shock: a retrospective cohort study using Japanese claims data	13
Construction of a predictive model and prognosis of left ventricular systolic dysfunction in patients with sepsis based on the diagnosis using left ventricular global longitudinal strain	13
Efficacy of probiotics in the prevention of diarrhea in ventilated critically ill ICU patients: meta-analysis of randomized control trials: author’s reply	13
Impact of the COVID-19 pandemic on critical care utilization in Japan: a nationwide inpatient database study	12
Changes in gene expression in healthcare workers during night shifts: implications for immune response and health risks	12
Efficacy of permissive underfeeding for critically ill patients: an updated systematic review and trial sequential meta-analysis	12
The method to identify invasive mechanical ventilation with Japanese claim data	12
Longitudinal proteomic analysis of pathophysiology in plasma and bronchoalveolar lavage fluid of patients with ARDS	12
Effectiveness of systemic thrombolysis on clinical outcomes in high-risk pulmonary embolism patients with venoarterial extracorporeal membrane oxygenation: a nationwide inpatient database study	11
Incidence and outcomes of in-hospital cardiac arrest in Japan 2011–2017: a nationwide inpatient database study	11
Autophagy and autophagic cell death in sepsis: friend or foe?	11
Prone positioning in ARDS patients supported with VV ECMO, what we should explore?	11
Development and validation of a nomogram to predict the risk of sepsis-associated encephalopathy for septic patients in PICU: a multicenter retrospective cohort study	11
Prognostic significance of delirium subtypes in critically ill medical and surgical patients: a secondary analysis of a prospective multicenter study	10
Erythropoietin as a critical prognostic indicator in ICU patients with sepsis: a prospective observational study	10
Prolonged use of neuromuscular blocking agents is associated with increased long-term mortality in mechanically ventilated medical ICU patients: a retrospective cohort study	10
Association of multiple sclerosis with mortality in sepsis: a population-level analysis	10
Non-invasive detection of a femoral-to-radial arterial pressure gradient in intensive care patients with vasoactive agents	10
External validation of 5A score model for predicting in-hospital mortality among the accidental hypothermia patients: JAAM-Hypothermia study 2018–2019 secondary analysis	10
Is it time to reconsider the administration of thiamine alone or in combination with vitamin C in critically ill patients? A meta-analysis of clinical trial studies	10
Association between the timing of ICU admission and mortality in patients with hospital-onset sepsis: a nationwide prospective cohort study	10
Association between the triglyceride–glucose index and the risk of acute kidney injury in critically ill patients with acute pancreatitis: a retrospective study	10
Immature granulocytes can help the diagnosis of pulmonary bacterial infections in patients with severe COVID-19 pneumonia	10
Onset timing and duration of augmented renal clearance in a mixed intensive care unit	10
Re-evaluating albumin use in traumatic brain injury	10
Rethinking diuretic use in acute kidney injury: effective prevention or false hope?	9
The cardioprotective and anti-inflammatory effect of inhaled nitric oxide during Fontan surgery in patients with single ventricle congenital heart defects: a prospective randomized study	9
Combination of Cv-aCO2/Ca-vO2 and Pv-aCO2 as markers of resuscitation or microcirculation in patients with septic shock: a pilot study	9
Effect of the COVID-19 pandemic on cardiac arrest resuscitation practices and outcomes in non-COVID-19 patients	9
Extracorporeal cardiopulmonary resuscitation with temperature management could improve the neurological outcomes of out-of-hospital cardiac arrest: a retrospective analysis of a nationwide multicenter	9
Association of continuous renal replacement therapy downtime with fluid balance gap and clinical outcomes: a retrospective cohort analysis utilizing EHR and machine data	9
Hospital and regional variations in intensive care unit admission for patients with invasive mechanical ventilation	9
Occurrence of pendelluft during ventilator weaning with T piece correlated with increased mortality in difficult-to-wean patients	9

Alteration of circulating redox balance in coronavirus disease-19-induced acute respiratory distress syndrome	9
Prognostic value of oxygen saturation index trajectory phenotypes on ICU mortality in mechanically ventilated patients: a multi-database retrospective cohort study	8
Two-year trajectory of functional recovery and quality of life in post-intensive care syndrome: a multicenter prospective observational study on mechanically ventilated patients with coronavirus disea	8
Temporal trends of medical cost and cost-effectiveness in sepsis patients: a Japanese nationwide medical claims database	8
Prehospital tranexamic acid for trauma victims	8
A prospective observational cohort study to identify inflammatory biomarkers for the diagnosis and prognosis of patients with sepsis	8
Recovery of consciousness after acute brain injury: a narrative review	8
A pilot multicenter randomized controlled trial on individualized blood pressure targets versus standard care among critically ill patients with shock	8
Accuracy evaluation of mainstream and sidestream end-tidal carbon dioxide monitoring during noninvasive ventilation: a randomized crossover trial (MASCAT-NIV trial)	8
Different definitions of feeding intolerance and their associations with outcomes of critically ill adults receiving enteral nutrition: a systematic review and meta-analysis	8
Impact of sympathetic hyperactivity induced by brain microglial activation on organ damage in sepsis with chronic kidney disease	7
Hemoglobin in cardiogenic shock: the lower, the poorer survival	7
A scoping review of registry captured indicators for evaluating quality of critical care in ICU	7
Efficacy of therapeutic drug monitoring-based antibiotic regimen in critically ill patients: a systematic review and meta-analysis of randomized controlled trials	7
Ultrafiltration in Japanese critically ill patients with acute kidney injury on renal replacement therapy	7
Low apolipoprotein A-II levels causally contribute to increased mortality in septic shock	7
Fundamental concepts and the latest evidence for esophageal pressure monitoring	7
Visualizing the dynamic mechanical power and time burden of mechanical ventilation patients: an analysis of the MIMIC-IV database	7
Association between the plasma-to-red blood cell ratio and survival in geriatric and non-geriatric trauma patients undergoing massive transfusion: a retrospective cohort study	7
Author’s response to the letter “Japanese clinical practice guidelines for rehabilitation in critically ill patients 2023 (J-ReCIP 2023)”	7
Increasing plasma calprotectin (S100A8/A9) is associated with 12-month mortality and unfavourable functional outcome in critically ill COVID-19 patients	7
Prevention and management of critical care complications in cardiogenic shock: a narrative review	6
Multivariate analysis of factors associated with first-pass success in blind placement of a post-pyloric feeding tube: a retrospective study	6
Comparison of balanced and unbalanced crystalloids as resuscitation fluid in patients treated for cardiogenic shock	6
Respiratory drive: a journey from health to disease	6
Effects of dexamethasone on immune dysfunction and ventilator-associated pneumonia in COVID-19 acute respiratory distress syndrome: an observational study	6
Mortality analysis among sepsis patients in and out of intensive care units using the Japanese nationwide medical claims database: a study by the Japan Sepsis Alliance study group	6
Long-term prevalence of PTSD symptom in family members of severe COVID-19 patients: a serial follow-up study extending to 18 months after ICU discharge	6
Optimization of levetiracetam dosing regimen in critically ill patients with augmented renal clearance: a Monte Carlo simulation study	6
Association between red blood cell distribution width and 30-day mortality in critically ill septic patients: a propensity score-matched study	5
Effects of normal saline versus lactated Ringer’s solution on organ function and inflammatory responses to heatstroke in rats	5
High driving pressure ventilation induces pulmonary hypertension in a rabbit model of acute lung injury	5
Concerns with the revised Japanese recommendation for administering vitamin C to septic patients	5
Long-term outcome of COVID-19 patients treated with helmet noninvasive ventilation vs. high-flow nasal oxygen: a randomized trial	5
Japanese Clinical Practice Guidelines for Rehabilitation in Critically Ill Patients 2023 (J-ReCIP 2023)	5
Sepsis-related coagulopathy treatment based on the disseminated intravascular coagulation diagnostic criteria: a post-hoc analysis of a prospective multicenter observational study	5
Ability of the respiratory ECMO survival prediction (RESP) score to predict survival for patients with COVID-19 ARDS and non-COVID-19 ARDS: a single-center retrospective study	5
Limitation of life sustaining measures in neurocritical care: sex, timing, and advance directive	5
Hydrocortisone, ascorbic acid, and thiamine (HAT) for sepsis and septic shock: a meta-analysis with sequential trial analysis	5
Normal saline versus Ringer’s solution and critical-illness mortality in acute pancreatitis: a nationwide inpatient database study	5
The impact of a preoperative nurse-led orientation program on postoperative delirium after cardiovascular surgery: a retrospective single-center observational study	5
Adjunctive ketamine for sedation in critically ill mechanically ventilated patients: an active-controlled, pilot, feasibility clinical trial	5
Respiratory physiotherapy for critically ill children: concern regarding a recommendation	5
Exploring the scope of inspiratory muscle training in difficult weaning: reflections on the multicentre RCT	5
Lacosamide dosing in patients receiving continuous renal replacement therapy	5
Mechanical ventilation in patients with cardiogenic pulmonary edema: a sub-analysis of the LUNG SAFE study	5
Chest CT findings in severe acute respiratory distress syndrome requiring V-V ECMO: J-CARVE registry	5
Height status matters for risk of mortality in critically ill children	5
Primary palliative care recommendations for critical care clinicians	5
The story of critical care in Asia: a narrative review	5