Pharmacology Research & Perspectives

Article	Citations
Issue Information	71
Modeling time‐delayed concentration‐QT effects with ACT‐1014‐6470, a novel oral complement factor 5a receptor 1 (C5a1 receptor) antagonist	48
Endoplasmic reticulum stress in the adipose tissue and monocyte chemoattractant protein‐1 are involved in tacrolimus‐induced diabetes mellitus	47
A549 Alveolar Carcinoma Spheroids as a Cytotoxicity Platform for Carboxyl‐ and Amine‐Polyethylene Glycol Gold Nanoparticles	36
The potencies and neurotoxicity of intrathecal levobupivacaine in a rat spinal model: Effects of concentration	35
Synthesis of salcaprozate sodium and its significance in enhancing pancreatic kininogenase absorption performance	33
Monitoring Serum Bisoprolol Concentrations in Patients With Heart Failure With Reduced Ejection Fraction: Results of a Pilot Study From Routine Health Care	27
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Clinical‐Pharmacological Drug Information Center of Hannover Medical School: Update From a Tertiary Care University Hospital (2022–2024)	26
Peripheral Neuropathy Associated With Proteasome Inhibitors and Immunomodulatory Drugs: A Pharmacovigilance Disproportionality Analysis Using VigiBase	26
Pharmacogenomics Education and Knowledge Assessment in Healthcare Curricula: A Scoping Review of the Middle East and North Africa Region	25
Quantitative analysis of the UDP‐glucuronosyltransferase transcriptome in human tissues	24
Cross‐modal embedding integrator for disease‐gene/protein association prediction using a multi‐head attention mechanism	23
FDA regulatory considerations for oncology drug development	22
The blockade of the TGF‐β pathway alleviates abnormal glucose and lipid metabolism of lipodystrophy not obesity	22
Role of Chinese Medicine Monomers in Dry Eye Disease: Breaking the Vicious Cycle of Inflammation	21
Patient safety in home care: A multicenter cross‐sectional study about medication errors and medication management of nurses	21
The roles of CYP2C19 and CYP3A4 in the in vitro metabolism of β‐eudesmol in human liver: Reaction phenotyping and enzyme kinetics	20
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Corrigendum	20
Safety, tolerability, and pharmacokinetics of a single ascending subcutaneous dose of GSK3772847 in healthy participants	19
Highlights of basic and clinical pharmacology from Africa	19
Investigation on the Use and Preauthorization of Carbapenems at A National Hospital in Vietnam: A Cross‐Sectional Study	18
Preclinical Evaluation of the Oral Toxicity, Genotoxicity, and Safety Pharmacology of LPM4870108, a Novel Potent Tropomyosin Receptor Kinase Inhibitor	18
Antioxidant potential of chlorogenic acid in Age‐Related eye diseases	18

Gastrin‐Releasing Peptide Facilitates Cholinergically Mediated Contractions of the Mouse Gastric Fundus	17
Exploring Cordycepin as a Neuroprotective Agent in Huntington's Disease: In Vitro and In Vivo Insights	16
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Comparative Efficacy of Different Targeted Therapies in Patients With Moderate‐to‐Severe Ulcerative Colitis: Systematic Review/Network Meta‐Analysis and Mechanistic Overview	16
Issue Information	16
Deciphering the Language of Assessment in Pharmacology Summative Written Assessments	16
The Influence of CYP2B6, GSTP1, and SLCO1B1 Star Allele‐Predicted Phenotypes and CBR1 Genetic Variants on Effectiveness Outcomes in Patients With Hepatocellular Carcinoma R	15
Jordanian community pharmacists' perceptions and experiences with continuing professional development – A comprehensive analysis	15
A phase I, single‐center, open‐label study to investigate the absorption, distribution, metabolism and excretion of encorafenib following a single oral dose of 100 mg [14C] encor	14
Hearing loss: The final frontier of pharmacology	13
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Impact of a computerized physician order entry system on medication safety in pediatrics—The AVOID study	13
Probe substrates assay estimates the effect of polyphyllin H on the activity of cytochrome P450 enzymes in human liver microsomes	13
Introducing a Professional Development Skill Building Platform Into a Biomedical Sciences Graduate Program Curriculum in Pharmacology	13
Pharmacokinetic study on the effect of ligustrazine–tangeretin co‐administration on the pharmacokinetics of ligustrazine and its potential mechanism in rats	13
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Rapamycin treatment increases survival, autophagy biomarkers and expression of the anti‐aging klotho protein in elderly mice	12
Prediction of cell cycle distribution after drug exposure by high content imaging analysis using low‐toxic DNA staining dye	12
The Absorption, Distribution, Metabolism, and Excretion of Binimetinib Following a Single Oral Dose of [14C]Binimetinib 45 mg in Healthy Male Participants	12
Differential Effects of IL4I1 Protein on Lymphocytes From Healthy and Multiple Sclerosis Patients	12
Quantitative understanding of HepaRG cells during drug‐induced intrahepatic cholestasis through changes in bile canaliculi dynamics	12
Inflammation and cardiovascular status impact midazolam pharmacokinetics in critically ill children: An observational, prospective, controlled study	12
Intravenous ibuprofen in postoperative pain and fever management in adults: A systematic review and meta‐analysis of randomized controlled trials	12
Information overdose: Student performance and perceptions of pharmacology resources on exams	12
The TAAR1 Agonist PCC0105004 Regulates Amygdala Synaptic Plasticity to Alleviate Anxiety‐Like Behaviors in Rats	12
Accounting for Time‐Varying Confounding in a Self‐Controlled Case Series of Fluoroquinolone Treatment for Uncomplicated Urinary Tract Infections and Risk of Collagen‐Related Events	11
Role of G protein‐coupled receptor kinases (GRKs) in β2‐adrenoceptor‐mediated glucose uptake	11
Issue Information	11
A Unified Explanation for Drug Repurposing and Pharmacological Pleiotropy Based on Classical and Statistical Thermodynamics	11
Clinical drug interactions between linezolid and other antibiotics: For adverse drug event monitoring	11
Effects of a recombinant humanized anti‐cocaine monoclonal antibody on the metabolism and distribution of cocaine in vitro and in mice	11
Concurrent Prescribing of Opioids and Sedative‐Hypnotic Drugs for Long‐Term Use in Australian General Practice: A Cross‐Sectional Analysis Using MedicineInsight	11
Not first‐line antihypertensive agents, but still effective—The efficacy and safety of imidazoline receptor agonists: A network meta‐analysis	10
The impact of phosphodiesterase‐5 inhibition or angiotensin‐converting enzyme inhibition on right and left ventricular remodeling in heart failure due to chronic volume overload	10
Exogenous melatonin's effect on salivary cortisol and amylase: A randomized controlled trial	10
Differential effects of glucose‐dependent insulinotropic polypeptide receptor/glucagon‐like peptide‐1 receptor heteromerization on cell signaling when expressed in HEK‐293 cells	10
Disposition of orally administered atuliflapon, a novel 5‐lipoxygenase‐activating protein inhibitor in healthy participants	10
In vitro evaluation suggests fenfluramine and norfenfluramine are unlikely to act as perpetrators of drug interactions	10
Ranitidine and the incidence of hypersensitivity reactions to paclitaxel: A retrospective cohort study	10
Exploring Australian pharmacists' views toward reducing the risk of medicines‐related harm in aged care residents	10
Comparing the Molecular Pharmacological Properties of Existing β‐Blockers to Determine the Theoretically Most “Ideal” Anti‐Cancer β‐Blocker	10
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Effect of cyclosporin A on respiratory viral replication in fully differentiated ex vivo human airway epithelia	9
Issue Information	9
Cannabinoid‐Induced Hyperphagia is Mediated by Increased Meal Frequency and the Orexin‐1 Receptor in Male Rats	9
Involvement of Piezo 1 mechanoceptors in vascular stiffness in isolated small resistance arteries of male and female Dahl salt‐sensitive hypertensive rats	9
Transfer of the Oral Gonadotropin‐Releasing Hormone Receptor Antagonist Relugolix Into Breast Milk of Healthy Lactating Women	9
Effects of Botrychium ternatum (Thunb) Sw. On Cytochrome P450	8
Involvement of β‐adrenoceptors in the cardiovascular responses induced by selective adenosine A 2A and A 2B	8
Upadacitinib‐Induced Hemolysis in a Patient With Glucose‐6‐Phosphate Dehydrogenase Deficiency—A Possible Adverse Drug Reaction	8

Pharmacist intervention to improve adherence to medication among heart failure patients at North East Ethiopia hospital	8
Trends in Lipid‐Lowering Agent Consumption in Croatia: A 25‐Year Observational Study	8
The Novel TRPV1 Agonist ST ‐6631 Improves Swallowing Function in Rat Models of Stroke‐Related Dysp	8
Effect of Spinacia oleracea on In Vitro Disintegration and Dissolution of Clopidogrel Bisulfate Ta	8
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Total body fluid is the factor that affects the pharmacokinetics of tolvaptan, and its efficacy, in acute worsening heart failure patients	8
Massive presence of off‐label medicines in Danish neonatal departments: A nationwide survey using national hospital purchase data	8
Clinical effect of different doses of ciprofol for induction of general anesthesia in elderly patients: A randomized, controlled trial	8
Colchicine has Dose‐Dependent Therapeutic Effects in a LPS ‐Induced Experimental Endotoxemia Model	8
Evidence‐based safety profile of oral ketorolac in adults: Systematic review and meta‐analysis	8
Comprehensive Evaluation of Methanolic Fruits Extract of Jatropha gossypifolia L.: Neuropharmacological, Cytotoxic, Anthelmintic,	8
Effect of vitamin D supplementation on clinical outcomes in adult patients with COVID‐19: A GRADE‐assessed systematic review and meta‐analysis of randomized controlled trials	8
Oral morphine induces spinal 5‐hydroxytryptamine (5‐HT) release using an opioid receptor‐independent mechanism	8
Effect of Interleukin‐6 Inhibitors on Rheumatoid Arthritis Pain: Overview of Evidence and Mechanistic Pathways	8
Biochemical and genetic biomarkers associated with nicotine dependence in Mexican smokers	7
Absorption, metabolism, and excretion of [14C]dersimelagon, an investigational oral selective melanocortin 1 receptor agonist, in preclinical species and healthy volunteers	7
In Vitro Hepatic Metabolism Input Parameters Support Toxicokinetic Simulations for the Formation of Methoxy Propionic Acid From β‐Isomer Propylene Glycol Methyl Ether	7
Team‐Based Learning in the Meta Horizon Workroom: A Pilot Study on Its Potential Effectiveness for Pharmacology Teaching	7
The Use of Proton Pump Inhibitors Among Adults in Norway—A Nationwide Drug Utilization Study	7
Treatment of [99mTc]Tc‐hydroxy‐diphosphonate ([99mTc]Tc‐HDP) extravasation using hyaluronidase	7
Analysis of in vitro and in vivo metabolism of zidovudine and gemfibrozil in trans‐chromosomic mouse line expressing human UGT2 enzymes	7
The N‐Acetyltransferase 2 Polymorphism and Susceptibility to Inflammatory Bowel Disease: A Case–Control Study	7
Comparison of the mathematical equation and trapezoidal approach for 24 h area under the plasma concentration‐time curve calculation in patients who received intravenous vancomycin in an acute care se	7
Pharmacology Research & Perspectives: A Decade of Progress	7
Encapsulation of Carvedilol in Nanomicelles Improves Central Hemodynamics and Target Organ Damage Protection in Spontaneously Hypertensive Rats	7
The Therapeutic Potential of Andrographolide and Its Derivatives in Inflammatory Diseases	7
Lobaric Acid Exhibits Anticancer Potential by Modulating the Wnt/β‐Catenin Signaling Pathway in MCF‐7 Cells	7
Mangiferin Against Respiratory Diseases: Pharmacological Targets and Prospects	7
Supporting Pediatric RSV Clinical Trials Through Close Epidemiological Surveillance During the SARS‐CoV‐2 Pandemic	6
Development and evaluation of an escape room based on general pharmacokinetics: Students' perceptions of its motivational climate	6
Telmisartan and losartan: The marked differences between their chemical and pharmacological properties may explain the difference in therapeutic efficacy in hospitalized patients with COVID‐19	6
Interaction of myricetin, ampelopsin (dihydromyricetin), and their sulfate metabolites with serum albumin, cytochrome P450 (CYP2C9, 2C19, and 3A4) enzymes,	6
RETRACTED: Ivermectin synergizes sorafenib in hepatocellular carcinoma via targeting multiple oncogenic pathways	6
Correlation of functional and radioligand binding characteristics of GPER ligands confirming aldosterone as a GPER agonist	6
Steroid Recognition in Adhesion GPCRs : A Structural and Pharmacological Perspective	6
Risk of Major Congenital Malformations Associated With the First‐Trimester Exposure to Antipsychotics: A Large Claims Database Study	6
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Computational design and molecular modeling of morphine derivatives for preferential binding in inflamed tissue	6
Effects of pharmacological doses of niacin on subacute glucocorticoid‐induced testicular damage in rats	6
Autocrine EGF and TGF‐α promote primary and acquired resistance to ALK/c‐Met kinase inhibitors in non‐small‐cell lung cancer	6
From Psychiatry to Oncology: Exploring the Anti‐Neoplastic Mechanisms of Aripiprazole and Its Potential Use in Cancer Treatment	6
Evaluation of Interstitial Lung Disease Complications Caused by Biologic Agents Using a Spontaneous Adverse Drug Reaction Reporting Database	6
A Clinical Practice‐Based Comparison of Conventional and Individualized Dosing Strategies for Therapeutic Enoxaparin	6
Cognitive and negative symptoms in schizophrenia with L‐Carnosine adjuvant therapy – A randomized double‐blind placebo‐controlled study	6
Risks of oral anticoagulants: Analysis of adverse drug reactions reported to the Portuguese National Pharmacovigilance System	6
Cromolyn sodium and masitinib combination inhibits fibroblast‐myofibroblast transition and exerts additive cell‐protective and antioxidant effects on a bleomycin‐induced in vitro fibrosis model	6
Aromatase Inhibitors and Dementia Risk: Putting Safety Into Perspective	6
A humanized anti‐cocaine mAb antagonizes the cardiovascular effects of cocaine in rats	6
Bioequivalence and the food effect of macitentan/tadalafil 10/20 fixed‐dose combination tablets versus the use of single‐component tablets in healthy subjects	6
Plasma concentration of atorvastatin metabolites correlates with low‐density lipoprotein cholesterol reduction in patients with coronary heart disease	6
The efficacy and safety of fingolimod plus standardized treatment versus standardized treatment alone for acute ischemic stroke: A systematic review and meta‐analysis	6
Effectiveness of edaravone in preventing contrast‐induced nephropathy in high‐risk patients undergoing coronary angiography: A randomized, double‐blind trial	6
Pharmacology and Regulation of Appetite and Food Intake	6
Evaluation and optimization of sample size of neonates and infants for pediatric clinical studies on cefiderocol using a model‐based approach	6
Vasoactivity of Rac GTPase , Cytohesin and Kinase Inhibitors in Renal Interlobar and Coronary Arteries Reveals Shared and Distinct Patterns of Inhibi	6
Are thyrotropin‐releasing hormone (TRH) and analog taltirelin viable reversal agents of opioid‐induced respiratory depression?	5
The gut–brain axis in appetite, satiety, food intake, and eating behavior: Insights from animal models and human studies	5
Issue Information	5
Gut Microbial Variations Associated With Proton Pump Inhibitor Use in the Boston Puerto Rican Health Study	5
Nicotine addiction and the influence of life adversity and acute stress on PYY: Prediction of early smoking relapse	5
Bayesian method application: Integrating mathematical modeling into clinical pharmacy through vancomycin therapeutic monitoring	5
HDAC4/5 Inhibitor, LMK‐235 Improves Animal Voluntary Movement in MPTP‐Induced Parkinson's Disease Model	5
Reported hepatotoxicity and hepatotoxicity guidance in the product information of protein kinase inhibitors in oncology registered at the European Medicines Agency	5
Psilocin, A Psychedelic Drug, Exerts Anticonvulsant Effects Against PTZ‐ and MES‐Induced Seizures in Mice via 5‐HT1A and CB1 Receptors: Involvement of Nitrergic, Opioidergic, and Kynurenine Pathways	5
Preclinical Evaluation of a Novel Molecule Targeting Nucleoside Homeostasis to Restore Energy Metabolism and Cognitive Function in Alzheimer's Disease	5
A Randomized, Open‐Label, Single‐Dose, Parallel‐Group Bioequivalence Study of Ferric Carboxymaltose Injection Under Fasting Conditions in Chinese Adult Subjects With Iron Deficiency Anemia	5
The endocannabinoid system in appetite regulation and treatment of obesity	5
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Reflections on the Core Concepts of Physiology and Pharmacology	5
Asciminib, a novel allosteric inhibitor of BCR‐ABL1, shows synergistic effects when used in combination with imatinib with or without drug resistance	5
Association of Pharmacologic Markers of Anti‐Tumor Necrosis Factor‐α Activity and Etanercept Effectiveness in Juvenile Idiopathic Arthritis	5
Differential effects of TRPM4 channel inhibitors on Guinea pig urinary bladder smooth muscle excitability and contractility: Novel 4‐chloro‐2‐[2‐(2‐chloro‐phenoxy)‐acetylamino]‐benzoic acid	5
The influence of SARS‐CoV‐2 infection on expression of drug‐metabolizing enzymes and transporters in a hACE2 murine model	5
Management of pharmacovigilance during the COVID‐19 pandemic crisis by the safety department of an academic sponsor: Lessons learnt and challenges from the EU DisCoVeRy clinical	5
Co‐created in vivo pharmacology practical classes using the novel organism Lumbriculus variegatus	5
Autocrine positive feedback of tumor necrosis factor from activated microglia proposed to be of widespread relevance in chronic neurological disease	5
Identification and neuroprotective properties of NA‐184, a calpain‐2 inhibitor	5
Pharmacokinetics, disposition, and biotransformation of the cardiac myosin inhibitor aficamten in humans	5
Shifting the National Paradigm: From DEIA to C.A.R.E. (Community, Advocacy, Resilience, and Empowerment) in Pharmacy Education	5
Effects of the HIV‐1 maturation inhibitor GSK3640254 on QT interval in healthy participants	5

A Comparison of the Molecular Pharmacological Properties of Current Short, Long, and Ultra‐Long‐Acting β2‐Agonists Used for Asthma and COPD	5
Enhancing Student Comprehension of Glucose Metabolism Visualization Through Virtual Simulation Platform: An Educational Approach	5
NMDA Receptor–Mediated Ca2+ Flux Attenuated by the NMDA Receptor/TRPM4 Interface Inhibitor Brophenexin	5
Age‐Dependent Differences in Canakinumab Safety: A Comprehensive Pharmacovigilance Analysis Using the FAERS Database	5