OOIR: Observatory of International Research

Papers

(The median citation count of Military Medical Research is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Impact of targeting the platelet-activating factor and its receptor in cancer treatment	335
Congenital hydrocephalus: a review of recent advances in genetic etiology and molecular mechanisms	239
Effectiveness of chest pain center accreditation on the hospital outcome of acute aortic dissection: a nationwide study in China	171
Revolutionizing treatment for disorders of consciousness: a multidisciplinary review of advancements in deep brain stimulation	158
Sexual dimorphism in the relationship between BMI and recent suicidal attempts in first-episode drug-naïve patients with major depressive disorder	95
Bioengineered materials with selective antimicrobial toxicity in biomedicine	73
Chronotype and self-reported sleep, alertness, and mental health in U.S. sailors	67
Regional trauma system development in Shenzhen, China: an 8-year journey	66
Secondary analysis of malaria rapid diagnostic tests from rounds 5–8 of WHO product testing with a focus on false-negative results	60
Melatonin attenuates radiation-induced cortical bone-derived stem cells injury and enhances bone repair in postradiation femoral defect model	60
Association of fluid balance trajectories with clinical outcomes in patients with septic shock: a prospective multicenter cohort study	59
Risk factors for musculoskeletal injuries in the military: a qualitative systematic review of the literature from the past two decades and a new prioritizing injury model	48
Wave-shaped microfluidic chip assisted point-of-care testing for accurate and rapid diagnosis of infections	41
TRIM72-mediated degradation of the short form of p62/SQSTM1 rheostatically controls selective autophagy in human cells	40
Molecular diagnostic approaches for enteric parasites: an issue of relevance for deployed soldiers?	39
Treatment and surveillance for non-muscle-invasive bladder cancer: a clinical practice guideline (2021 edition)	38
Mesenchymal stem cell-derived extracellular vesicles in skin wound healing: the risk of senescent drift induction in secretome-based therapeutics	32
Chemical exposures and suspected impact on Gulf War Veterans	32
Global burden of benign prostatic hyperplasia, urinary tract infections, urolithiasis, bladder cancer, kidney cancer, and prostate cancer from 1990 to 2021	30
Gastroenteropancreatic neuroendocrine neoplasms: current development, challenges, and clinical perspectives	30
Hydration status, body composition, and anxiety status in aeronautical military personnel from Spain: a cross-sectional study	29
A comprehensive guide to miniaturized percutaneous nephrolithotomy: International Alliance of Urolithiasis (IAU) consensus on best practices	29
Adhesive cryogel particles for bridging confined and irregular tissue defects	28
Emerging roles of ADP-dependent glucokinase in prostate cancer	28
Differential roles of RIG-I like receptors in SARS-CoV-2 infection	28

Targeting NR1D1 in organ injury: challenges and prospects	27
BET inhibitors potentiate melanoma ferroptosis and immunotherapy through AKR1C2 inhibition	26
Elevated FBXL6 activates both wild-type KRAS and mutant KRASG12D and drives HCC tumorigenesis via the ERK/mTOR/PRELID2/ROS axis in mice	25
Gulf War illness with or without post-traumatic stress disorder: differential symptoms and immune responses	25
ADP-dependent glucokinase controls metabolic fitness in prostate cancer progression	25
Immune checkpoint inhibition mediated with liposomal nanomedicine for cancer therapy	24
Digital in-line holographic microscopy for label-free identification and tracking of biological cells	24
The implications of single-cell RNA-seq analysis in prostate cancer: unraveling tumor heterogeneity, therapeutic implications and pathways towards personalized therapy	24
Extracellular vesicles in the pathogenesis and treatment of acute lung injury	23
Activatable fluorescent probes for imaging and diagnosis of rheumatoid arthritis	23
Excellent effects and possible mechanisms of action of a new antibody–drug conjugate against EGFR-positive triple-negative breast cancer	23
Correction to: Establishment and effectiveness evaluation of a scoring system for exertional heat stroke by retrospective analysis	20
The relationship between chronic PTSD, cortical volumetry and white matter microstructure among Australian combat veterans	20
Correction to: Efficient and rapid conversion of human astrocytes and ALS mouse model spinal cord astrocytes into motor neuron-like cells by defined small molecules	20
Global, regional, and national burden of kidney, bladder, and prostate cancers and their attributable risk factors, 1990–2019	19
The marriage of immunomodulatory, angiogenic, and osteogenic capabilities in a piezoelectric hydrogel tissue engineering scaffold for military medicine	19
Mesenchymal stem cell-derived extracellular vesicles in skin wound healing: roles, opportunities and challenges	19
Sepsis-induced immunosuppression: mechanisms, diagnosis and current treatment options	18
Propionate and butyrate attenuate macrophage pyroptosis and osteoclastogenesis induced by CoCrMo alloy particles	18
Activated Drp1 regulates p62-mediated autophagic flux and aggravates inflammation in cerebral ischemia-reperfusion via the ROS-RIP1/RIP3-exosome axis	18
Strategies for promoting neurovascularization in bone regeneration	17
A cross-sectional study of olfactory and taste disorders among COVID-19 patients in China	17
Role of signaling pathways in age-related orthopedic diseases: focus on the fibroblast growth factor family	16
Radiomics and radiogenomics: extracting more information from medical images for the diagnosis and prognostic prediction of ovarian cancer	16
Nickel’s carcinogenicity: the need of more studies to progress	16
Correction to: Bioengineered materials with selective antimicrobial toxicity in biomedicine	16
National age-specific mortality trends for cervical and breast cancers in urban–rural areas of China from 2009 to 2021: a population-based analysis	15
TGF-β1 mediates hypoxia-preconditioned olfactory mucosa mesenchymal stem cells improved neural functional recovery in Parkinson’s disease models and patients	14
Crisis in the gut: navigating gastrointestinal challenges in Gulf War Illness with bioengineering	14
Intelligent medicine in focus: the 5 stages of evolution in robot-assisted surgery for prostate cancer in the past 20 years and future implications	14
Bone-organ axes: bidirectional crosstalk	14
Chinese expert consensus on diagnosis and treatment of trauma-induced hypercoagulopathy	13
Effect of early administration of tetracosactide on mortality and host response in critically ill patients requiring rescue surgery: a sensitivity analysis of the STOPSHOCK phase 3 randomized controll	13
Dietary methionine supplementation promotes mice hematopoiesis after irradiation	13
Viral sepsis: diagnosis, clinical features, pathogenesis, and clinical considerations	13
Propofol postconditioning ameliorates hypoxia/reoxygenation induced H9c2 cell apoptosis and autophagy via upregulating forkhead transcription factors under hyperglycemia	12
Dementia in military and veteran populations: a review of risk factors—traumatic brain injury, post-traumatic stress disorder, deployment, and sleep	12
Lethal means and suicide prevention among military veterans	12
Nanosensitizers for sonodynamic therapy for glioblastoma multiforme: current progress and future perspectives	12
Monkeypox outbreak in the age of COVID-19: a new global health emergency	12
Autologous omentum transposition for regeneration of a renal injury model in rats	12
Oral administration of asparagine and 3-indolepropionic acid prolongs survival time of rats with traumatic colon injury	11
An integrated microfluidics platform with high-throughput single-cell cloning array and concentration gradient generator for efficient cancer drug effect screening	11
Melatonin inhibits ESCC tumor growth by mitigating the HDAC7/β-catenin/c-Myc positive feedback loop and suppressing the USP10-maintained HDAC7 protein stability	11
Correction to: Nanomedicine‐boosting icaritin-based immunotherapy of advanced hepatocellular carcinoma	10
Alleviating mitochondrial dysfunction in diabetic cardiomyopathy through the Adipsin and Irak2 pathways	10
Research on the development methodology for clinical practice guidelines for organic integration of traditional Chinese and Western medicine	10
Heart-brain axis: low blood pressure during off-pump CABG surgery is associated with postoperative heart failure	10
Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice	10
Aspartoacylase suppresses prostate cancer progression by blocking LYN activation	10

Novel radiopaque ethanol injection: physicochemical properties, animal experiments, and clinical application in vascular malformations	9
Preemptive targeted muscle reinnervation: the single incision approach should be avoided in trans-tibial traumatic amputation	9
Insights gained from single-cell analysis of chimeric antigen receptor T-cell immunotherapy in cancer	9
N-terminal pro-brain natriuretic peptide – a significant biomarker of disease development and adverse prognosis in patients with exertional heat stroke	9
MELK prevents radiofrequency ablation-induced immunogenic cell death and antitumor immune response by stabilizing FABP5 in hepatocellular malignancies	8
Artificial intelligence-driven radiomics study in cancer: the role of feature engineering and modeling	8
Data analysis guidelines for single-cell RNA-seq in biomedical studies and clinical applications	8
DPP-4 inhibitors and GLP-1RAs: cardiovascular safety and benefits	8
Correction: Management of granulomatous lobular mastitis: an international multidisciplinary consensus (2021 edition)	8
Comparative study on the antituberculous effect and mechanism of the traditional Chinese medicines NiuBeiXiaoHe extract and JieHeWan	8
Regulatory T cells in skin regeneration and wound healing	8
Multifaceted functions of Drp1 in hypoxia/ischemia-induced mitochondrial quality imbalance: from regulatory mechanism to targeted therapeutic strategy	8
Interferon-α stimulates DExH-box helicase 58 to prevent hepatocyte ferroptosis	7
Targeting mitochondrial quality control: new therapeutic strategies for major diseases	7
Targeting PPARα in low ambient temperature exposure-induced cardiac dysfunction and remodeling	7
Epidemiological trends of urinary tract infections, urolithiasis and benign prostatic hyperplasia in 203 countries and territories from 1990 to 2019	7
Recent applications of EEG-based brain-computer-interface in the medical field	7
Explosive eye injuries: characteristics, traumatic mechanisms, and prognostic factors for poor visual outcomes	7
Bioengineered skin organoids: from development to applications	7
Supraglottic jet oxygenation and ventilation (SJOV) for resuscitation of injured soldiers and people in war field	7
The minimal active domain of human salivary histatin 1 is efficacious in promoting acute skin wound healing	7
China stroke surveillance report 2021	7
Multimodal therapy strategies based on hydrogels for the repair of spinal cord injury	7
Estimation of radiation-induced health hazards from a “dirty bomb” attack with radiocesium under different assault and rescue conditions	7
Alteration of mitochondrial protein succinylation against cellular oxidative stress in cancer	6
Monkeypox outbreak: A novel threat after COVID-19?	6
Cell fusion in the pathogenesis of COVID-19	6
Elucidating regulatory processes of intense physical activity by multi-omics analysis	6
Advances in single-cell sequencing: insights from organ transplantation	6
N6-methyladenosine modification of CENPK mRNA by ZC3H13 promotes cervical cancer stemness and chemoresistance	5
Novel gene therapy for rheumatoid arthritis with single local injection: adeno-associated virus-mediated delivery of A20/TNFAIP3	5
Deep learning-based lung sound analysis for intelligent stethoscope	5
Small molecules facilitate single factor-mediated sweat gland cell reprogramming	5
The efficacy of tucatinib-based therapeutic approaches for HER2-positive breast cancer	5
Prediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia: randomized trials and multiomics analysis	5
Monitoring of urinary iodine concentration in naval pilots: should iodine be supplemented or limited at coastal stations?	5
Veterans utilizing a federally qualified health center: a clinical snapshot	5
Expert consensus on the monitoring and treatment of sepsis-induced immunosuppression	5
What benefit can be obtained from magnetic resonance imaging diagnosis with artificial intelligence in prostate cancer compared with clinical assessments?	5
Adipose tissue macrophages: implications for obesity-associated cancer	5
Introduction of monkeypox virus in Benin, 2022	5
GPR65 as a potential novel therapeutic target for the treatment of hepatic fibrosis	4
Neuronal Panx1 drives peripheral sensitization in experimental plantar inflammatory pain	4
A prediction model for moderate to severe acute kidney injury in people with heart failure	4
Hans Chinese consume less O2 for muscular work than european-american	4
Military traumatic brain injury: a challenge straddling neurology and psychiatry	4
Recent advances in CRISPR-based genome editing technology and its applications in cardiovascular research	4
The correlation between gut microbiome and atrial fibrillation: pathophysiology and therapeutic perspectives	4
Adipsin inhibits Irak2 mitochondrial translocation and improves fatty acid β-oxidation to alleviate diabetic cardiomyopathy	4
The Frank-Starling mechanism is not enough: blood volume expansion prominently decreases pulmonary O2 uptake	4
FOXO1-expressing neutrophils: a double-edged sword in traumatic brain injury	4
Elimination of methicillin-resistant Staphylococcus aureus biofilms on titanium implants via photothermally-triggered nitric oxide and immunotherapy for enhanced osseointegration	4
Mitochondrial complex I: the key to sustained microglia activation and neuroinflammation maintenance	4
CRISPR/Cas9 nickase mediated signal amplification integrating with the trans-cleavage activity of Cas12a for highly selective and sensitive detection of single base mutations	4
Targeting the epigenome to reinvigorate T cells for cancer immunotherapy	4
PANX1-mediated ATP release confers FAM3A’s suppression effects on hepatic gluconeogenesis and lipogenesis	4
FDA-approved cannabidiol [Epidiolex®] alleviates Gulf War Illness-linked cognitive and mood dysfunction, hyperalgesia, neuroinflammatory signaling, and declined neurogenesis	4
Exosomal mediators in sepsis and inflammatory organ injury: unraveling the role of exosomes in intercellular crosstalk and organ dysfunction	4
Towards a better understanding of antimicrobial resistance dissemination: what can be learnt from studying model conjugative plasmids?	4
Cellular therapeutics and immunotherapies in wound healing – on the pulse of time?	3
Exosome autoantibody biomarkers for detection of lung cancer	3
Deciphering the molecular interplay and tumorigenesis in hepatocellular carcinoma through insights into FBXL6 and KRASG12D	3
FGF2 is overexpressed in asthma and promotes airway inflammation through the FGFR/MAPK/NF-κB pathway in airway epithelial cells	3
Biomaterial-based mechanical regulation facilitates scarless wound healing with functional skin appendage regeneration	3
Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effect	3
AKR1C3 as a therapeutic target to overcome erlotinib resistance in lung adenocarcinoma	3
Interleukin-1 receptor associated kinase 2 is a functional downstream regulator of complement factor D that controls mitochondrial fitness in diabetic cardiomyopathy	3
Frailty as a sequela of burn injury: a post hoc analysis of the “RE-ENERGIZE” multicenter randomized-controlled trial and the National Health Interview Survey	3
Tackling exosome and nuclear receptor interaction: an emerging paradigm in the treatment of chronic diseases	3
Targeting vulnerable microcircuits in the ventral hippocampus of male transgenic mice to rescue Alzheimer-like social memory loss	3
A comprehensive look at the psychoneuroimmunoendocrinology of spinal cord injury and its progression: mechanisms and clinical opportunities	3
Antimicrobial resistance crisis: could artificial intelligence be the solution?	3
Single-cell transcriptome profiling of sepsis identifies HLA-DRlowS100Ahigh monocytes with immunosuppressive function	3
Common mtDNA variations at C5178a and A249d/T6392C/G10310A decrease the risk of severe COVID-19 in a Han Chinese population from Central China	3
The emerging role of Panx1 as a potential therapeutic target for chronic pain	3
Expression dynamics of periodic transcripts during cancer cell cycle progression and their correlation with anticancer drug sensitivity	3
Identification of antimalarial targets of chloroquine by a combined deconvolution strategy of ABPP and MS-CETSA	3
Applications and prospects of cryo-EM in drug discovery	3