OOIR: Observatory of International Research

Papers

(The TQCC of Military Medical Research is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
ADP-dependent glucokinase controls metabolic fitness in prostate cancer progression	349
Substantia nigra-related gene polymorphisms associated with acute antipsychotic-induced movement disorders	325
Maladaptive reorganization of mediodorsal thalamus as a central mechanism in neuropathic pain-related sleep disorders	204
Mesenchymal stem cell-derived extracellular vesicles in skin wound healing: roles, opportunities and challenges	167
Are metformin-based combination approaches beneficial for non-small cell lung cancer: evidence from experimental and clinical studies	147
Correction to: Bioengineered materials with selective antimicrobial toxicity in biomedicine	127
Oral administration of asparagine and 3-indolepropionic acid prolongs survival time of rats with traumatic colon injury	107
MELK prevents radiofrequency ablation-induced immunogenic cell death and antitumor immune response by stabilizing FABP5 in hepatocellular malignancies	103
National and subnational burden and causes of anemia in China from 1990 to 2023: findings from the Global Burden of Disease Study 2023	87
The roles, mechanisms, and therapeutic implications of glucocorticoids in glucose and lipid metabolism	87
Explosive eye injuries: characteristics, traumatic mechanisms, and prognostic factors for poor visual outcomes	86
Bone-organ axes: bidirectional crosstalk	82
Nanozyme-driven multifunctional dressings: moving beyond enzyme-like catalysis in chronic wound treatment	75
The correlation between gut microbiome and atrial fibrillation: pathophysiology and therapeutic perspectives	70
A comprehensive look at the psychoneuroimmunoendocrinology of spinal cord injury and its progression: mechanisms and clinical opportunities	64
The efficacy of tucatinib-based therapeutic approaches for HER2-positive breast cancer	60
Adipose tissue macrophages: implications for obesity-associated cancer	56
Recent advances in CRISPR-based genome editing technology and its applications in cardiovascular research	56
Targeting the epigenome to reinvigorate T cells for cancer immunotherapy	53
Introduction of monkeypox virus in Benin, 2022	53
The Frank-Starling mechanism is not enough: blood volume expansion prominently decreases pulmonary O2 uptake	48
Chinese expert consensus on prevention, diagnosis, and management of venous thromboembolism in adult burn patients (2024)	46
FDA-approved cannabidiol [Epidiolex®] alleviates Gulf War Illness-linked cognitive and mood dysfunction, hyperalgesia, neuroinflammatory signaling, and declined neurogenesis	46
Engineered immune-driven theranostics for clinical cardiology	45
Neuroinflammation in mild respiratory COVID-19: insights into cognitive impairment in milder cases	43

Tackling exosome and nuclear receptor interaction: an emerging paradigm in the treatment of chronic diseases	40
Artificial intelligence and machine learning for hemorrhagic trauma care	40
Interleukin-1 receptor associated kinase 2 is a functional downstream regulator of complement factor D that controls mitochondrial fitness in diabetic cardiomyopathy	40
Expression dynamics of periodic transcripts during cancer cell cycle progression and their correlation with anticancer drug sensitivity	40
Dual-locked targeted alpha-emitter enhanced tumor immunotherapy via Diels–Alder reaction-based self-immolative molecular cage strategy	39
Antibacterial efficacy of a chitosan-based hydrogel loaded with epsilon poly-L-lysine and poly(I:C) extracellular vesicles for the control of polymicrobial extremity wound infections in a porcine poly	39
Research advances in smart responsive-hydrogel dressings with potential clinical diabetic wound healing properties	38
γ neuromodulations: unraveling biomarkers for neurological and psychiatric disorders	38
Guidance of development, validation, and evaluation of algorithms for populating health status in observational studies of routinely collected data (DEVELOP-RCD)	37
Ionizable drug delivery systems for efficient and selective gene therapy	35
Risk factor control in relation to mortality and life expectancy among people with type 2 diabetes: results from 3 nationwide cohort studies	34
Clonal hematopoiesis of indeterminate potential: a multisystem hub bridging hematopoietic dysfunction with non-hematopoietic diseases	34
Immune cells: potential carriers or agents for drug delivery to the central nervous system	33
Recent developments in application of single-cell RNA sequencing in the tumour immune microenvironment and cancer therapy	32
A review on cell damage, viability, and functionality during 3D bioprinting	30
Insights into the underlying pathogenesis and therapeutic potential of endoplasmic reticulum stress in degenerative musculoskeletal diseases	30
The disease burden attributable to tobacco use in China and its provinces from 1990−2023: an analysis from the Global Burden of Disease Study 2023	29
Advances in the isolation, cultivation, and identification of gut microbes	28
Disentangling the effects of PTSD from Gulf War Illness in male veterans via a systems-wide analysis of immune cell, cytokine, and symptom measures	28
Correction to: Pushing the frontiers of military medical excellence: updates, progress and future needs	28
Pericytes protect rats and mice from sepsis-induced injuries by maintaining vascular reactivity and barrier function: implication of miRNAs and microvesicles	28
National mortality burden attributable to the unprecedented heatwave in 2022 in China	28
Spatial transcriptomics: recent developments and insights in respiratory research	27
Bioactive peptides and proteins for tissue repair: microenvironment modulation, rational delivery, and clinical potential	27
Endothelial barrier and sepsis: mechanisms and potential therapeutic strategies	27
An unfolding monkeypox outbreak in Europe and beyond	27
Immune microenvironment dynamics in pregnant patients with concomitant autoimmune diseases: mechanisms, challenges, and clinical significance	26
Global patterns and trends in cancer-related premature death and their impact on life expectancy across 185 countries: a population-based analysis	24
Targeting the central and peripheral nervous system to regulate bone homeostasis: mechanisms and potential therapies	23
Biomaterials science and surface engineering strategies for dental peri-implantitis management	23
Endophilin A2 controls touch and mechanical allodynia via kinesin-mediated Piezo2 trafficking	23
A comprehensive guide to miniaturized percutaneous nephrolithotomy: International Alliance of Urolithiasis (IAU) consensus on best practices	23
Immune checkpoint inhibition mediated with liposomal nanomedicine for cancer therapy	22
Cell-free DNA in sepsis: from molecular insights to clinical management	22
BET inhibitors potentiate melanoma ferroptosis and immunotherapy through AKR1C2 inhibition	22
Digital in-line holographic microscopy for label-free identification and tracking of biological cells	22
Interferon-α stimulates DExH-box helicase 58 to prevent hepatocyte ferroptosis	21
Treatment and surveillance for non-muscle-invasive bladder cancer: a clinical practice guideline (2021 edition)	21
Insights gained from single-cell analysis of chimeric antigen receptor T-cell immunotherapy in cancer	21
Sepsis-induced immunosuppression: mechanisms, diagnosis and current treatment options	21
Exploring the diagnostic potential: magnetic particle imaging for brain diseases	20
Engineering of functional auditory neurons from human induced pluripotent stem cells	20
Glucocorticoids trigger muscle-liver crosstalk to attenuate acute liver injury and promote liver regeneration via the FGF6-FGFBP1 axis	20
Type 2 diabetes does not inevitably shorten life expectancy	19
Virtual medicine: medical AI in human health and diseases	19
Melatonin inhibits ESCC tumor growth by mitigating the HDAC7/β-catenin/c-Myc positive feedback loop and suppressing the USP10-maintained HDAC7 protein stability	18
Prediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia: randomized trials and multiomics analysis	18
Research on the development methodology for clinical practice guidelines for organic integration of traditional Chinese and Western medicine	18
Nanosensitizers for sonodynamic therapy for glioblastoma multiforme: current progress and future perspectives	18
CRISPR/Cas9 nickase mediated signal amplification integrating with the trans-cleavage activity of Cas12a for highly selective and sensitive detection of single base mutations	18

Reprogramming neural-tumor crosstalk: emerging therapeutic dimensions and targeting strategies	18
Monitoring of urinary iodine concentration in naval pilots: should iodine be supplemented or limited at coastal stations?	18
Dual character of surface engineering on SN38 prodrug nano-assemblies: divergent effects on in vitro and in vivo behavior	18
Deep learning-based lung sound analysis for intelligent stethoscope	17
A prediction model for moderate to severe acute kidney injury in people with heart failure	17
β-catenin initiates peritoneal fibrosis by triggering mitochondrial fission-mediated mesothelial cell senescence fate transition	17
Antimicrobial resistance crisis: could artificial intelligence be the solution?	17
The cellular response capacity (CRC) as a novel immunomonitoring approach in sepsis	17
Integrating artificial intelligence with human reasoning in oncology: questions on real-world implementation and patient-centric evidence	16
What benefit can be obtained from magnetic resonance imaging diagnosis with artificial intelligence in prostate cancer compared with clinical assessments?	16
Sepsis in burns: lessons learned, challenges remain	16