OOIR: Observatory of International Research

Papers

(The TQCC of Military Medical Research is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Substantia nigra-related gene polymorphisms associated with acute antipsychotic-induced movement disorders	337
ADP-dependent glucokinase controls metabolic fitness in prostate cancer progression	319
Mesenchymal stem cell-derived extracellular vesicles in skin wound healing: roles, opportunities and challenges	202
Are metformin-based combination approaches beneficial for non-small cell lung cancer: evidence from experimental and clinical studies	155
Oral administration of asparagine and 3-indolepropionic acid prolongs survival time of rats with traumatic colon injury	144
Correction to: Bioengineered materials with selective antimicrobial toxicity in biomedicine	121
Bone-organ axes: bidirectional crosstalk	114
National and subnational burden and causes of anemia in China from 1990 to 2023: findings from the Global Burden of Disease Study 2023	105
Nanozyme-driven multifunctional dressings: moving beyond enzyme-like catalysis in chronic wound treatment	97
MELK prevents radiofrequency ablation-induced immunogenic cell death and antitumor immune response by stabilizing FABP5 in hepatocellular malignancies	85
Explosive eye injuries: characteristics, traumatic mechanisms, and prognostic factors for poor visual outcomes	83
The correlation between gut microbiome and atrial fibrillation: pathophysiology and therapeutic perspectives	79
A comprehensive look at the psychoneuroimmunoendocrinology of spinal cord injury and its progression: mechanisms and clinical opportunities	76
The efficacy of tucatinib-based therapeutic approaches for HER2-positive breast cancer	70
Adipose tissue macrophages: implications for obesity-associated cancer	69
Introduction of monkeypox virus in Benin, 2022	64
Recent advances in CRISPR-based genome editing technology and its applications in cardiovascular research	59
Targeting the epigenome to reinvigorate T cells for cancer immunotherapy	53
The Frank-Starling mechanism is not enough: blood volume expansion prominently decreases pulmonary O2 uptake	52
FDA-approved cannabidiol [Epidiolex®] alleviates Gulf War Illness-linked cognitive and mood dysfunction, hyperalgesia, neuroinflammatory signaling, and declined neurogenesis	52
Chinese expert consensus on prevention, diagnosis, and management of venous thromboembolism in adult burn patients (2024)	50
Engineered immune-driven theranostics for clinical cardiology	45
Interleukin-1 receptor associated kinase 2 is a functional downstream regulator of complement factor D that controls mitochondrial fitness in diabetic cardiomyopathy	44
Neuroinflammation in mild respiratory COVID-19: insights into cognitive impairment in milder cases	44
Tackling exosome and nuclear receptor interaction: an emerging paradigm in the treatment of chronic diseases	43

Dual-locked targeted alpha-emitter enhanced tumor immunotherapy via Diels–Alder reaction-based self-immolative molecular cage strategy	42
Expression dynamics of periodic transcripts during cancer cell cycle progression and their correlation with anticancer drug sensitivity	42
γ neuromodulations: unraveling biomarkers for neurological and psychiatric disorders	40
Artificial intelligence and machine learning for hemorrhagic trauma care	40
Research advances in smart responsive-hydrogel dressings with potential clinical diabetic wound healing properties	40
Guidance of development, validation, and evaluation of algorithms for populating health status in observational studies of routinely collected data (DEVELOP-RCD)	39
Ionizable drug delivery systems for efficient and selective gene therapy	38
Immune cells: potential carriers or agents for drug delivery to the central nervous system	37
Risk factor control in relation to mortality and life expectancy among people with type 2 diabetes: results from 3 nationwide cohort studies	37
Clonal hematopoiesis of indeterminate potential: a multisystem hub bridging hematopoietic dysfunction with non-hematopoietic diseases	37
Recent developments in application of single-cell RNA sequencing in the tumour immune microenvironment and cancer therapy	36
Insights into the underlying pathogenesis and therapeutic potential of endoplasmic reticulum stress in degenerative musculoskeletal diseases	35
A review on cell damage, viability, and functionality during 3D bioprinting	34
Advances in the isolation, cultivation, and identification of gut microbes	34
An unfolding monkeypox outbreak in Europe and beyond	32
Spatial transcriptomics: recent developments and insights in respiratory research	32
Correction to: Pushing the frontiers of military medical excellence: updates, progress and future needs	30
National mortality burden attributable to the unprecedented heatwave in 2022 in China	30
Global patterns and trends in cancer-related premature death and their impact on life expectancy across 185 countries: a population-based analysis	30
Endophilin A2 controls touch and mechanical allodynia via kinesin-mediated Piezo2 trafficking	29
Immune microenvironment dynamics in pregnant patients with concomitant autoimmune diseases: mechanisms, challenges, and clinical significance	28
Disentangling the effects of PTSD from Gulf War Illness in male veterans via a systems-wide analysis of immune cell, cytokine, and symptom measures	28
Endothelial barrier and sepsis: mechanisms and potential therapeutic strategies	27
Pericytes protect rats and mice from sepsis-induced injuries by maintaining vascular reactivity and barrier function: implication of miRNAs and microvesicles	27
Bioactive peptides and proteins for tissue repair: microenvironment modulation, rational delivery, and clinical potential	27
Digital in-line holographic microscopy for label-free identification and tracking of biological cells	27
Targeting the central and peripheral nervous system to regulate bone homeostasis: mechanisms and potential therapies	27
Biomaterials science and surface engineering strategies for dental peri-implantitis management	27
BET inhibitors potentiate melanoma ferroptosis and immunotherapy through AKR1C2 inhibition	26
A comprehensive guide to miniaturized percutaneous nephrolithotomy: International Alliance of Urolithiasis (IAU) consensus on best practices	26
Immune checkpoint inhibition mediated with liposomal nanomedicine for cancer therapy	24
Cell-free DNA in sepsis: from molecular insights to clinical management	22
Treatment and surveillance for non-muscle-invasive bladder cancer: a clinical practice guideline (2021 edition)	22
Sepsis-induced immunosuppression: mechanisms, diagnosis and current treatment options	21
Engineering of functional auditory neurons from human induced pluripotent stem cells	21
Research on the development methodology for clinical practice guidelines for organic integration of traditional Chinese and Western medicine	21
Exploring the diagnostic potential: magnetic particle imaging for brain diseases	21
Glucocorticoids trigger muscle-liver crosstalk to attenuate acute liver injury and promote liver regeneration via the FGF6-FGFBP1 axis	21
Virtual medicine: medical AI in human health and diseases	21
Interferon-α stimulates DExH-box helicase 58 to prevent hepatocyte ferroptosis	21
Nanosensitizers for sonodynamic therapy for glioblastoma multiforme: current progress and future perspectives	19
Reprogramming neural-tumor crosstalk: emerging therapeutic dimensions and targeting strategies	19
Insights gained from single-cell analysis of chimeric antigen receptor T-cell immunotherapy in cancer	19
Type 2 diabetes does not inevitably shorten life expectancy	19
Melatonin inhibits ESCC tumor growth by mitigating the HDAC7/β-catenin/c-Myc positive feedback loop and suppressing the USP10-maintained HDAC7 protein stability	19
Deep learning-based lung sound analysis for intelligent stethoscope	18
What benefit can be obtained from magnetic resonance imaging diagnosis with artificial intelligence in prostate cancer compared with clinical assessments?	18
A prediction model for moderate to severe acute kidney injury in people with heart failure	18
Dual character of surface engineering on SN38 prodrug nano-assemblies: divergent effects on in vitro and in vivo behavior	18
CRISPR/Cas9 nickase mediated signal amplification integrating with the trans-cleavage activity of Cas12a for highly selective and sensitive detection of single base mutations	18

Antimicrobial resistance crisis: could artificial intelligence be the solution?	17
Prediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia: randomized trials and multiomics analysis	17
Cellular therapeutics and immunotherapies in wound healing – on the pulse of time?	17
β-catenin initiates peritoneal fibrosis by triggering mitochondrial fission-mediated mesothelial cell senescence fate transition	17
Frailty as a sequela of burn injury: a post hoc analysis of the “RE-ENERGIZE” multicenter randomized-controlled trial and the National Health Interview Survey	17
Monitoring of urinary iodine concentration in naval pilots: should iodine be supplemented or limited at coastal stations?	17
Deciphering the molecular interplay and tumorigenesis in hepatocellular carcinoma through insights into FBXL6 and KRASG12D	17