OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Virus Eradication is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
PP 1.33 – 00167 Integrated single-cell multi-omic profiling of HIV latency reversal	42
PP 3.8 – 00137 Characterization of the HIV-1 subtype C reservoir during ART in South-African men and women	33
OP 1.6 – 00138 Role of UHRF1 in HIV-1 transcriptional repression through epigenetic and non-epigenetic mechanisms	16
OP 5.2 – 00070 Characterization of a dual PTPN1/PTPN2 inhibitor to target latent HIV reservoirs	15
PP1.19 – 00036 Unexpected Redundancy of the TNF/NF-kB Axis in HIV-1 Restriction and Latency Reversal in Primary Human MDM Polarized to M1 Cells	14
PP6.5 – 00086 Regulation of AAV transgene expression using nanoparticledelivered Cre-recombinase	14
8.2 – 00072 Early intervention with an indoline CD4-mimetic compound that sensitizes HIV-1-infected cells to ADCC favors post-treatment HIV control in humanized mice	14
Cascade of care among hepatitis B patients in Maastricht, the Netherlands, 1996 to 2018	12
Factors associated with unquantifiable total HIV-1 DNA in peripheral blood in persons living with HIV: An observational study	12
ST2.4 – 00035 Bach controls seeding of HIV reservoirs in memory CD4+ T cells	11
Dynamic changes in immune cell subsets in blood and lymph node over the course of acute HIV infection	11
2-Deoxyglucose as a therapeutic strategy for EBV-associated gastric carcinoma: Glycolytic and lytic reactivation inhibition under hypoxic conditions	11
Editorial JVE 10.2	11
5.5 – 00117 HIV-Tocky system in primary CD4+T cells joined with transcriptomic and epigenomic analysis to discover mechanism involves in the establishment of latency during acute infection	10
PP1.16 – 00059 Identification of solo-LTR HIV provirus in vitro	10
PP5.11 – 00071 A novel in vitro model for studying HIV infection and latency in microglia: SIV Vpx-treated EcoHIV-infected CHME5	10
OP 1.2 – 00157 HIV Silencing and Cell Survival Signatures of HIV-Infected CD4 T Cell Transcriptomes under Antiretroviral Therapy (ART)	8
OP 3.1 HIV Persistence in women, an update	8
Highlights of HIV Cure in IAS, Montréal	7
PP 2.1 – 00014 Impact of early antiretroviral therapy on tissue resident myeloid cells in the liver and lung of SIV-infected rhesus macaques	7
Impact of hepatitis B vaccination programs in Vietnam evaluated by estimating HBsAg prevalence	6
Langya virus outbreak in China, 2022: Are we on the verge of a new pandemic?	6
PP 7.8 – 00060 Slowing or Reversal of Decay of Intact Proviruses Over Two Decades of Suppressive ART	6
Origin, distribution and incidence of human rabies in Côte d’Ivoire from 2013 to 2023	6
PP7.1-00174 Active HIV reservoir in jejunum exhibit distinct phenotypic features and evoke innate cell redistribution	5

8.4 – 00081 IL-15/IL-15RA Therapy Enhances Control of Viral Rebound in SIVInfected Macaques	5
PP 6.5 – 00205 Utilization of high-throughput assays and deep-learning for selection of CRISPR/Cas9-gRNA pairs used in an HIV-1 cure strategy	5
PP6.7 – 00070 Blockade of HIV-1 Latency Reversal in CD4+ T Cells from ARTsuppressed PLWH by the HIV-1 Antisense Transcript AST	5
OP 4.3 – 00112 Leaky reservoirs are associated with HIV-specific cd4 and CD8 T-cell responses	5
Substantial uneven proliferation of CD4+ T cells during recovery from acute HIV infection is sufficient to explain the observed expanded clones in the HIV reservoir	5
OP 3.8 – 00066 Characterization of the HIV-1 viral reservoir in subtype B early treated individuals	5
PP5.3 – 00166 Treatment with AZD5582 + het-IL15 transiently disrupts the reservoir establishment in SIV-infected macaques	5
Combining treatment for chronic hepatitis C with opioid agonist therapy is an effective microelimination strategy for people who inject drugs with high risk of non-adherence to direct-acting antiviral	5
The HIV-2 OGH double reporter virus shows that HIV-2 is less cytotoxic and less sensitive to reactivation from latency than HIV-1 in cell culture	5
OP 3.6 – 00023 Effect of HIV-1 infection, viral particle production, and proviral integration site on CD4+ T cell proliferation	5
PP2.5 – 00122 The role of Vpr in the epigenetic regulation of HIV-1 latency	5
OP 1.4 – 00053 Definitive evidence of a persistent HIV reservoir in human brain myeloid cells despite ART	5
PP 1.27 – 00147 Role of the pol gene enhancer in HIV-1 transcription and replication in myeloid infected cells	4
Assessment of dengue virus threat to blood safety and community health: A single center study in northern Egypt	4
PP 1.26 – 00143 Understanding HIV transcription in Kaposi's sarcoma tumors during antiretroviral therapy	4
PP 3.20 – 00154 Epigenetic modifying compounds negatively impact viral replication within primary human macrophages	4
OP 4.8 – 00149 CD8+ T cells promote hiv latency in CD4+ T cells through the downmodulation of NF-kB	4
Editorial 10.4	3
Design and analysis considerations for early phase clinical trials in hepatitis B (HBV) cure research: the ACTG A5394 study in persons with both HIV and HBV	3
PP 1.11 – 00075 Selective nuclear retention of spliced and unspliced HIV-1 mRNAs following latency reversal	3
PP3.4 – 00100 Retinoids enhance NK effector functions against HIV infected CD4 T cells	3
PP4.16 – 00014 Reduction of HIV-1 reservoir following mpox infection	3
Perceptions of HIV cure and willingness to participate in HIV cure-related trials among people enrolled in the Netherlands cohort study on acute HIV infection	3
PP2.3 – 00168 Blocks to HIV transcriptional initiation, elongation, and splicing contribute differentially to inefficient virus reactivation across authentic reservoir-harboring CD4+ T-cell clones	3
PP 3.14 – 00190 Ex vivo response to latency reversal agents of CD4+ T cell subsets and monocyte derived HIV-1 subtype C LTR from individuals on suppressive cART	3
PP7.2 – 00169 Longitudinal Persistence of HIV DNA in CSF Over 4 Years Despite Up to 20 Years of ART	3
1.6 – 00161 HIV-1 Antisense Transcripts are frequent in FOXP3-negative Treglike cells expressing markers of persistence in vivo during acute HIV- 1 infection	3
Editorial Board	3
PP4.6 – 00115 Disruption of intestinal germinal centers during HIV infection	3
Relatively high interest but limited active engagement in HIV cure research: Awareness, interest, and information-seeking among affected communities in the Netherlands	3
Heat shock protein: a double-edged sword linking innate immunity and hepatitis B virus infection	3
PP3.3 – 00121 Exploring the Effects of Benzodiazepines on a Novel Mechanism of Control in HIV-1 Infected Human Monocyte Derived Macrophages	3
PP 1.35 – 00172 A histone deacetylase network regulates epigenetic reprogramming and viral silencing in HIV infected cells	3
PP 4.21 – 00050 Seeding of long-lived HIV cellular reservoirs through differentiation of infected CCR5+CD4+ T cells into central memory cells	2
PP2.4 – 00157 Development of a Virology Quality Assurance Program to Assess Inter-lab Reproducibility of HIV-1 Reservoir Assays	2
The impact of acute stress on the HIV reservoir: a prospective interventional trial	2
PP3.1 – 00160 Macrophage Training Reactivates Latent HIV-1 from HAARTsuppressed PBMCs of PLWH	2
PP 4.27 – 00202 Single-cell RNA sequencing reveals CBD genetic signature in monocyte gene expression	2
OP 2.2 – 00200 Characterization of the SIV tissue reservoir transcriptional environment at the single focus level during ART and post ATI	2
To prescreen or not to prescreen for broadly neutralizing antibody sensitivity in HIV cure-related trials	2
PP 4.10 – 00119 Multiomic dynamics of the cellular HIV reservoir after rebound during ATI	2
Assessment of the general population knowledge about the emergence of Nipah virus outbreak in Bangladesh: A nationwide cross-sectional study	2
Evolution of split-protein technologies in virology: From mechanistic discovery and diagnostics to therapeutic promise	2
PP6.8 – 00062 Evaluating the Combination Effect of Autophagy Induction and CAR T Cell Therapy on “Kick-and-Kill” HIV Reservoir Depletion	2
PP 7.2 – 00006 Acceptability of Home-Based Blood Collection Device for Viral Load Testing in HIV Cure Trials with Analytical Treatment Interruptions	2
PP 1.34 – 00170 Intestinal endothelial cells substantially increase HIV infection and latency in resting and activated CD4+ T cells, particularly affecting CCR6+ Th17 subpopulation	2
Bypassing primary antiretroviral therapy centres in Sub-Saharan Africa: An integrative review of the theoretical and empirical literature	2
OP 2.8 – 00193 Enhancing PKC Modulator HIV Latency Reversing Agents	2
PP7.3 – 00149 Ultra-sensitive secondary structure RNA quantification in the HIV Reservoir Assay Validation and Evaluation Network (RAVEN) using the BioSnap assay	2
PP5.5 – 00152 IL-15, Type I interferon, and amino acid pathways are correlated with SIV reservoir size and magnitude of viral rebound post-ATI in SIV-infected infant rhesus macaques	2

OP 2.5 – 00048 Targeting the SIV reservoir with Alemtuzumab	2
A liberalized approach to directly observed therapy for HCV retains excellent cure rates among PWID in Vienna	1
PP 4.18 – 00213 Dynamics and antiviral role of TOX+ TCF1+ CD39+ CD8 T cells in lymphoid tissue of SIV-infected rhesus macaques	1
The central nervous system is a potential reservoir and possible origin of drug resistance in hepatitis B infection	1
8.5 – 00015 Changes in the composition of HIV-1 reservoir of PWH on ART and dasatinib	1
Editorial JVE 9.4	1
PP 1.41 – 00092 Spatial Transcriptomics and the Search for the Latent HIV-1 Cell Niche	1
PP 3.7 – 00128 Genetic variation of the HIV-1 subtype C transmitted/founder viruses long terminal repeat elements and the impact on transcription activation potential and clinical disease outcomes	1
PP8.2 – 00162 Protective MHC-1 alleles extend time to SIV rebound following neutralizing antibody treatment at time of ART release	1
Editorial Board	1
PP 3.4 – 00079 HIV-1 clade C reservoir characteristics in early and chronic treated infection	1
PP 1.2 – 00011 Structural rearrangements in the nucleus localize latent HIV proviruses to a perinucleolar zone supportive of early transcription reactivation	1
PP 4.5 – 00064 Differentiation Enhances Reactivation of Latent HIV-1 Reservoir in CD4+ T Cells in PLWH With > 4 Years of Viral Suppression	1
4.5 – 00020 Control of HIV infection is associated with enhanced CD8T cell functionality during consecutive analytical treatment interruptions	1
PP 2.9 – 00125 Impact of latency reversal agents on estrogen receptor alpha gene and protein expression	1
PP4.8 – 00099 Activation of Immune Effector Responses in Newborns with Perinatal HIV infection	1
Navigating the HIV/AIDS epidemic in Bangladesh: A comprehensive retrospective analysis of epidemiological trends and sex-specific disparities (1990–2021) with long-term ARIMA forecasting to 2050 for s	1
PP6.4 – 00096 Therapeutic efficacy of AAV-delivered HIV-1 bNAbs to prevent SHIV rebound in Rhesus macaques	1
OP 1.1 Sequencing HIV: Significance and Impact	1
PP 2.11 – 00144 Transcriptional and translational SIV profiles of peripheral and lymphoid CD4+ T cells of viremic and ART-suppressed Rhesus macaques	1
OP 4.4 – 00018 HIV reservoir burden associates with numbers of HIV-specific CD8+ T cells under long-term antiretroviral therapy and prevents them from differentiating into functional memory cells	1
PP5.10 – 00033 Ex vivo HIV DNA integration in STAT3 drives T cell persistence—A model of HIV-associated T cell lymphoma	1
5.3 – 00106 Macrophage-tropic TF SHIV D infected NHP model of reservoir persistence, decay and pathogenesis on suppressive anti-retroviral therapy	1
OP 6.3 – 00150 Delivery and long-term expression of CCR5-blocking monoclonal antibody Leronlimab with AAV for ART-free remission from SHIV viremia	1
PP 4.11 – 00126 Autologous Neutralizing Antibodies Increase with Early Antiretroviral Therapy and Shape HIV Rebound after Treatment Interruption	1
PP 5.1 – 00045 Impact of Intrinsic and Extrinsic Factors on the Pharmacokinetics of Long-Acting Lenacapavir for Treatment of HIV	1
PP 1.5 – 00040 Mapping of genetic interaction networks identifies a nucleosomal modification complex for silencing HIV	1
PP 1.6 – 00047LAIR-1 is a negative regulator of SIV-specific CD8 T cells during chronic SIV infection	1
HIV-1 latency: From acquaintance to confidant	1
PP2.2 – 00177 Late Increases in Intact Proviral DNA Reveal Variable HIV-1 Reservoir Dynamics	1
PP 2.14 – 00162 Elucidating the effects of combination therapy with Venetoclax and IAP inhibitor AZD5582 in SIV-infected, ART-suppressed macaques	1
PP5.4 – 00017 Barcoded HIV-1 reveals proviruses associated with cell clonal proliferation or viremia have distinct chromatin patterns	1
Editorial JVE 8.4	1
PP5.2 – 00170 Plasma levels of Galectin-3 and -9 correlate with gut microbial dysregulation and residual mucosal SIV in Rhesus Macaques	1
Vaccination against COVID-19 among healthcare workers as a cocoon strategy for people living with HIV	1
OP 6.6 – 00134 Viral Suppression in SHIV-infected Rhesus Macaques following AAVmediated Delivery of Closer-to-germline Monoclonal Antibodies	1
Achieving the global agenda toward HIV cure calls for establishing a research-for-cure academy in West and Central Africa	1
PP 2.15 – 00169 Macrophages are the primary source of virus in semen and male genital tract organs in acutely and chronically infected rhesus macaques	1
Hepatitis B prevalence in an endemic area of hepatitis C virus: A population-based study implicated in hepatitis elimination in Thailand	1
Management of chronic hepatitis B in Uganda: A five-year experience following the initiation of a national sensitization and care campaign	1
Assessing favipiravir impact on SARS-CoV-2 transmission within households: Insights from a multi-center study (FaviPrev)	1
OP 6.8 – 00102 In vivo evolution of env in SHIV-AD8-infected rhesus macaques after AAV-eCD4-Ig therapy	1
The ethical case for placebo control in HIV-cure-related studies with ART interruption	1
OP 3.2 – 00056 Clonally expanded HIV-1 proviruses with 5′-Leader defects can give rise to nonsuppressible residual viremia and complicate ART management	1
PP 4.4 – 00059 Quantification of HIV Reservoirs in Brain: focus in bystander damage	1
PP 3.12 – 00180 Distinct HIV-1 resistance profiles against bNAb in intact vs defective viral genomes	1
PP 4.1 – 00013 Vaccine-mediated induction of elite control-associated CD8+ cytotoxic T lymphocytes in Mamu-B*08+ Indian rhesus macaques does not protect against intrarectal SIVmac239 acquisition	1
PP4.9 – 00090 Changes in CPSF6 and SC35 expression and subcellular localization induced by dasatinib and ponatinib as mechanism to interfere with HIV-1 proviral integration in macrophages	1
3.4 – 00150 Unbiased Genome-Wide CRISPR Screens in Primary Human CD4+ T Cells Identify Novel Proviral and Anti-viral HIV Host Factors	1
PP 7.10 – 00088 Macrophage-Tropic HIV-1 Variants Contribute to Pediatric Rebound Viremia off ART	1
2.1 – 00040 Lenacapavir impairs gag proteins expression by HIV-infected cells	1
OP 3.3 – 00030 Inducible replication-competent HIV proviruses persist in memory CD4+ T cells expressing high levels of the integrin VLA-4 (α4β1)	1
ST2.3 – 00128 Targeting Myeloid Reservoirs Harboring Replication-Competent HIV	1
PP 1.21 – 00118 Regulation of HIV-1 persistence by the CARD8 inflammasome	1
OP 2.4 – 00145 No Evidence of Ongoing Viral Replication in SIV-Infected Macaques on Combination Antiretroviral Therapy Initiated in the Chronic Phase of Infection Despite Elevated Residual Plasma Vira	1