OOIR: Observatory of International Research

Papers

(The TQCC of Regenerative Biomaterials is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Engineering stem cell exosomes promotes the survival of multi-territory perforator flap in diabetes via regulating anti-inflammatory and angiogenesis	54
Recombinant humanized type III collagen improves ovarian function via ITGA2-mediated mitochondrial function restoration in granulosa cells and extracellular matrix remodeling	54
The cutting-edge advancements in biomaterials under the guidance of intelligence and bionics	52
Biofabrication of zinc-reinforced PLA scaffolds by FDM for bone tissue engineering	46
Black phosphorus-loaded mineralized UV-responsive chitosan hydrogel for enhanced osteogenesis and antibacterial activity	39
Strategic incorporation of metal ions in bone regenerative scaffolds: multifunctional platforms for advancing osteogenesis	36
A neurovascularized bone regeneration strategy for mandibular and alveolar bone defects based on elastin-like biomaterials	35
Engineered collagen XVII-loaded dissolving microneedle patch for promoting hair regrowth in androgenic alopecia	33
Coordination-based nanocomposite hydrogel promotes tissue regeneration under infection-compromised conditions	32
Chondroitin sulfate reinforces mitochondrial redox homeostasis to enable integrated intervertebral disc regeneration	31
Advances in osseointegration of biomimetic mineralized collagen and inorganic metal elements of natural bone for bone repair	28
Mitochondria-targeted nanotechnology in cardiovascular diseases: a review of recent advances	27
Recombinant human collagen type III microgel: an advanced injectable dermal filler for rejuvenating aging skin	25
A dual-functional injectable polysaccharide hydrogel incorporating oxygen-carrying nanoemulsion and VEGF for enhancing islet survival and glycemic control in diabetic mice	24
Mesoporous bioactive glass–recombinant collagen III nanocomposite capsule promotes skin wound healing via adaptive immune modulation	23
Recent advances in biomaterials for osteosarcoma treatment	23
Injectable cartilage microtissues based on 3D culture using porous gelatin microcarriers for cartilage defect treatment	22
A dual-functional PEG-tyrosine hydrogel with photothermal effect and antioxidant capacity for cancer therapy and tissue regeneration	19
The Sr-HA-loaded PLGA cage structure combines cells to construct a bone tissue repair unit	19
Advanced materials and devices strategies of mechanical stimulation for tissue regeneration	19
Acellular nerve perineurium repairs peripheral nerve injuries in a rat model via ECM-mediated barrier and optimization of the regenerative microenvironment	19
Engineering a cell wall-deficient protoplast-incorporated hydrogel for infected wound healing	18
A novel polyester–drug nanoconjugate with subtype selectivity for high efficacy against PSMA-positive prostate cancer	17
The use of concentrated growth factors in guiding bone regeneration after microsurgical endodontic surgery for periapical lesions	17
Betaine based organ preservation solution alleviates renal allograft I/R injury by protecting endothelial cells	16

Advanced bone-targeted nanomaterials for the systemic treatment of osteoporosis	16
Bioinspired and smart material systems for auricular cartilage engineering: toward microenvironment-responsive and self-regulating scaffolds	14
Engineered hierarchical 3D scaffold promotes bone regeneration through enhanced mechanotransduction	14
Functionalized magnetic hydrogel encapsulation of human dental follicle stem cells under a static magnetic field enhances multi-site bone regeneration	13
Combined therapeutic strategy based on blocking the deleterious effects of AGEs for accelerating diabetic wound healing	13
Correction to: Synergistic Chemo-/Photothermal-therapy Based on Supercritical Technology-assisted Chitosan-Indocyanine Green/Luteolin Nanocomposites for Skin Wound Healing	13
Magnesium ion hydrogel enhances resistance to radiation-induced bone injury by modulating the bone immune microenvironment and promoting microvascularization	12
Hybrid hydrogel system integrating thermoresponsive microspheres and KGN-loaded nanofibers enables efficient cartilage matrix regeneration	12
Navigating oxidative stress in oral bone regeneration: mechanisms and reactive oxygen species-regulating biomaterial strategies	12
Promoting cell proliferation and collagen production with ascorbic acid 2-phosphate-releasing poly(l-lactide-co-ε-caprolactone) membranes for treating pelvic organ prolapse	11
TiO2 nanotubes regulate osteo-adipogenic balance through SREBP1 to determine the fate of bone marrow mesenchymal stem cells	10
Comparative effects of platelets and plasma-derived mitochondria in early-phase Achilles tendon inflammation	10
LL-37—biofunctionalized titanium improves soft tissue seal surrounding the dental implant from the perspective of optimizing a race to the surface	9
Bioengineered nasal septum implant with 3D-printed silicone and chondrocyte-seeded fibrin hydrogel	9
Design of novel interlocked bi-layer NiTi braided stent with ultra-thin walls for urinary tract obstruction treatment	9
Retraction of: Gelatin-biofermentative unsulfated glycosaminoglycans semi-interpenetrating hydrogels via microbial-transglutaminase crosslinking enhance osteogenic potential of dental pulp stem cells	9
Iron–quercetin nanocomplex preconditioning reprograms the mesenchymal stem cell secretome to drive angiogenic, fibroblast and immunoregulatory wound repair	8
Tetrahedral framework nucleic acids enhance the chondrogenic potential of human umbilical cord mesenchymal stem cells via the PI3K/AKT axis	8
Photothermal and cascade ROS generative multilayer as intraocular lens surface coating for effective posterior capsular opacification inhibition	8
L-arginine-loaded microneedle patch enhances diabetic wound healing by regulating macrophage polarisation and mitochondrial homeostasis	7
Three-dimensionally-printed biphasic PCL/ β -TCP scaffold with spatially confined GelMA/CS hydrogel for coordinated osteochondral regeneration	7
Heterogeneous zinc/catechol-derived resin microsphere-functionalized composite hydrogels with antibacterial and anti-inflammatory activities promote bacterial-infected wound healing	7
Targeting delayed healing tissues: immune reprogramming of adaptive immune cells by biomaterials	7
Protein conformational transition microenvironment in silk fibroin hydrogels: proliferation and chondrogenesis of encapsulated stem cells	7
Hyaluronic acid methacrylate/laponite hydrogel loaded with BMP4 and maintaining its bioactivity for scar-free wound healing	6
Matrix metalloproteinase-2 and pH-responsive drug eluting multilayer as intraocular lens coating to improve the posterior capsule opacification inhibition	6
Synergistic integration of biomaterials in orthopedic implantation for infection preventing and tissue engineering	6
ROS-scavenging lipoic acid-modified chitosan hydrogels with rapid photocrosslinked ability accelerates peripheral nerve regeneration	6
A novel inherent fluorescence biodegradable polyurethane	6
Electrospinning based biomaterials for biomimetic fabrication, bioactive protein delivery and wound regenerative repair	6
Recombinant collagen for the repair of skin wounds and photo-aging damage	6
Three-dimensional-printed strontium-incorporated β-TCP bioceramic triply periodic minimal surface scaffolds with enhanced angiogenic and osteogenic properties	5
Ascorbic acid 2-phosphate-releasing poly-l-lactide-co-epsilon-caprolactone membranes enhance tissue regeneration: first in vivo insights for pelvic organ	5
A ‘frost formation’-inspired near-infrared-responsive nitric oxide-releasing hydrogel for enhancing fat graft survival	5
A review on thermoresponsive PNIPAM hydrogels for regenerative medicine: from mechanical design to tissue adhesion	5
Pathology-guided design of injectable hydrogels for precision therapy and cartilage regeneration in osteoarthritis	5
Ginseng-derived exosomes loaded in fibrin gel promote retinal ganglion cell survival in glaucoma by exerting anti-inflammatory effects through modulating microglial polarization	5
Magnetic chitosan nanoparticle-exosome hydrogel enhances bladder function in diabetic bladder dysfunction via activating the FAK-p38 MAPK-GATA4 axis in adipose-derived mesenchymal stromal cells	5
Corilagin functionalized decellularized extracellular matrix as artificial blood vessels with improved endothelialization and anti-inflammation by reactive oxygen species scavenging	5