OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Pathology Clinical Research is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
SWI/SNF‐deficiency defines highly aggressive undifferentiated endometrial carcinoma	39
Combined CCNE1 high‐level amplification and overexpression is associated with unfavourable outcome in tubo‐ovarian high‐grade serous carcinoma	30
Adult‐type granulosa cell tumor of the ovary: a FOXL2‐centric disease	27
Higher prevalence of pulmonary macrothrombi in SARS‐CoV‐2 than in influenza A: autopsy results from ‘Spanish flu’ 1918/1919 in Switzerland to Coronavirus disease 2019	27
DNA methylation‐based profiling of bone and soft tissue tumours: a validation study of the ‘DKFZ Sarcoma Classifier’	26
Characterisation of cardiac pathology in 23 autopsies of lethal COVID‐19	26
Prognostic assessment of resected colorectal liver metastases integrating pathological features, RAS mutation and Immunoscore	24
Spectrum of histiocytic neoplasms associated with diverse haematological malignancies bearing the same oncogenic mutation	23
Preoperative systemic chemotherapy alters the histopathological growth patterns of colorectal liver metastases	23
Inter‐observer agreement for the histological diagnosis of invasive lobular breast carcinoma	22
Hypothesis‐free deep survival learning applied to the tumour microenvironment in gastric cancer	21
The epithelial–mesenchymal transition regulators Twist, Slug, and Snail are associated with aggressive tumour features and poor outcome in prostate cancer patients	20
Detection of tumor‐derived cell‐free DNA from colorectal cancer peritoneal metastases in plasma and peritoneal fluid	20
Semantic annotation for computational pathology: multidisciplinary experience and best practice recommendations	20
Spatial analysis of tumor‐infiltrating lymphocytes in histological sections using deep learning techniques predicts survival in colorectal carcinoma	19
Practical considerations for optimising homologous recombination repair mutation testing in patients with metastatic prostate cancer	19
Sarcoma and the 100,000 Genomes Project: our experience and changes to practice	19
Relationship between immune checkpoint proteins, tumour microenvironment characteristics, and prognosis in primary operable colorectal cancer	18
Identification of NTRK gene fusions in lung adenocarcinomas in the Chinese population	17
Variability in grading of ductal carcinoma in situ among an international group of pathologists	16
Significance of tumour regression in lymph node metastases of gastric and gastro‐oesophageal junction adenocarcinomas	16
Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer	16
The ethical challenges of artificial intelligence‐driven digital pathology	16
Selection of endometrial carcinomas for p53 immunohistochemistry based on nuclear features	15
Immune cell infiltrates as prognostic biomarkers in pancreatic ductal adenocarcinoma: a systematic review and meta‐analysis	15

An analysis of HER2 amplification in cervical adenocarcinoma: correlation with clinical outcomes and the International Endocervical Adenocarcinoma Criteria and Classification	14
TFE3 activation in a TSC1‐altered malignant PEComa: challenging the dichotomy of the underlying pathogenic mechanisms	13
Analysis of a novel immune checkpoint, Siglec‐15, in pancreatic ductal adenocarcinoma	13
Dysbalance of ACE2 levels – a possible cause for severe COVID‐19 outcome in COPD	13
Expression of invadopodia markers can identify oral lesions with a high risk of malignant transformation	12
Expression of proteins associated with the Warburg‐effect and survival in colorectal cancer	12
Quick Annotator: an open‐source digital pathology based rapid image annotation tool	12
Immunohistochemistry for CCR4 C‐terminus predicts CCR4 mutations and mogamulizumab efficacy in adult T‐cell leukemia/lymphoma	11
Loss of NF2 defines a genetic subgroup of non‐FOS‐rearranged osteoblastoma	11
Explainability and causability in digital pathology	11
More than just acral melanoma: the controversies of defining the disease	11
Homologous recombination deficiency is inversely correlated with microsatellite instability and identifies immunologically cold tumors in most cancer types	10
Prognostic value of patient‐derived xenograft engraftment in pediatric sarcomas	10
MYC amplifications are common events in childhood osteosarcoma	10
Morphological, immunohistochemical, and genetic analyses of bronchiolar adenoma and its putative variants	10
Tertiary lymphoid structures favor outcome in resected esophageal squamous cell carcinoma	10
Pattern of placental alkaline phosphatase (PLAP) expression in human tumors: a tissue microarray study on 12,381 tumors	10
Intra‐ and extra‐cranial BCOR‐ITD tumours are separate entities within the BCOR‐rearranged family	10
CD24 is a surrogate for ‘immune‐cold’ phenotype in aggressive large B‐cell lymphoma	10
pTDP‐43 aggregates accumulate in non‐central nervous system tissues prior to symptom onset in amyotrophic lateral sclerosis: a case series linking archival surgical biopsies with clinical p	9
The presence of tumour‐infiltrating neutrophils is an independent adverse prognostic feature in clear cell renal cell carcinoma	9
Colonic epithelial cathelicidin (LL‐37) expression intensity is associated with progression of colorectal cancer and presence of CD8⁺ T cell infiltrate	9
Papillary thyroid carcinoma tall cell variant shares accumulation of mitochondria, mitochondrial DNA mutations, and loss of oxidative phosphorylation complex I integrity with oncocytic tumors	9
Diagnostic and prognostic implications of a three‐antibody molecular subtyping algorithm for non‐muscle invasive bladder cancer	9
PD‐L1 and PD‐L2 expression in pancreatic ductal adenocarcinoma and their correlation with immune infiltrates and DNA damage response molecules	9
A distinct repertoire of cancer‐associated fibroblasts is enriched in cribriform prostate cancer	9
Characterizing the tumor microenvironment in rare renal cancer histological types	8
Reliable computational quantification of liver fibrosis is compromised by inherent staining variation	8
Greater utility of molecular subtype rather than epithelial‐to‐mesenchymal transition (EMT) markers for prognosis in high‐risk non‐muscle‐invasive (HGT1) bladder cancer	8
A combination of stromal PD‐L1 and tumoral nuclear β‐catenin expression as an indicator of colorectal carcinoma progression and resistance to chemoradiotherapy in locally advanced rectal ca	8
Prognostic value of absolute quantification of mutated KRAS in circulating tumour DNA in lung adenocarcinoma patients prior to therapy	8
A series of COVID‐19 autopsies with clinical and pathologic comparisons to both seasonal and pandemic influenza	8
The prognostic marker elastin correlates with epithelial–mesenchymal transition and vimentin‐positive fibroblasts in gastric cancer	8
KLF2 inhibits colorectal cancer progression and metastasis by inducing ferroptosis via the PI3K/AKT signaling pathway	8
Malignant transformation of salivary gland pleomorphic adenoma: proof of principle	8
Understanding the ethical and legal considerations of Digital Pathology	8
An evaluation of the tumour endothelial marker CLEC14A as a therapeutic target in solid tumours	8