Cell Discovery

Article	Citations
Generation of live mice from haploid ESCs with germline-DMR deletions or switch	181
The STROMICS genome study: deep whole-genome sequencing and analysis of 10K Chinese patients with ischemic stroke reveal complex genetic and phenotypic interplay	164
Two long-lasting human monoclonal antibodies cross-react with monkeypox virus A35 antigen	141
Mettl3-m6A-NPY axis governing neuron–microglia interaction regulates sleep amount of mice	129
Pig blastocyst-like structure models from embryonic stem cells	118
Publisher Correction: SGF29 nuclear condensates reinforce cellular aging	118
Genetic tracing uncovers the importance of epithelial-to-mesenchymal transition in small cell lung cancer chemotherapy resistance but not metastasis	103
Structure basis for sugar specificity of gustatory receptors in insects	93
Engineered, nucleocytoplasmic shuttling Cas13d enables highly efficient cytosolic RNA targeting	90
Deep sampling of gRNA in the human genome and deep-learning-informed prediction of gRNA activities	87
The TRIM37 variants in Mulibrey nanism patients paralyze follicular helper T cell differentiation	86
Structural mechanisms of human sodium-coupled high-affinity choline transporter CHT1	80
Calcium influx-induced lytic cell death disrupts skin immune homeostasis	76
Intercellular genetic tracing by alternative synthetic Notch signaling	65
Spermidine-eIF5A axis is essential for muscle stem cell activation via translational control	65
Design of a mutation-integrated trimeric RBD with broad protection against SARS-CoV-2	64
Heterotypic vaccination responses against SARS-CoV-2 Omicron BA.2	61
EGFR blockade confers sensitivity to cabozantinib in hepatocellular carcinoma	61
Lineage-coupled clonal capture identifies clonal evolution mechanisms and vulnerabilities of BRAFV600E inhibition resistance in melanoma	61
Human SERPINA3 induces neocortical folding and improves cognitive ability in mice	58
Author Correction: The Cardamine enshiensis genome reveals whole genome duplication and insight into selenium hyperaccumulation and tolerance	56
Non-adjuvanted interferon-armed RBD protein nasal drops protect airway infection from SARS-CoV-2	55
Smooth muscle-derived macrophage-like cells contribute to multiple cell lineages in the atherosclerotic plaque	54
Rapid screening of TCR-pMHC interactions by the YAMTAD system	54
SFRP4+ stromal cell subpopulation with IGF1 signaling in human endometrial regeneration	54

A bispecific nanobody dimer broadly neutralizes SARS-CoV-1 & 2 variants of concern and offers substantial protection against Omicron via low-dose intranasal administration	53
RNAi-directed knockdown induces nascent transcript degradation and premature transcription termination in the nucleus	52
Structures of Mec1/ATR kinase endogenously stimulated by different genotoxins	51
Landscape of the RBD-specific IgG, IgM, and IgA responses triggered by the inactivated virus vaccine against the Omicron variant	50
PPARδ inhibition blocks the induction and function of tumor-induced IL-10+ regulatory B cells and enhances cancer immunotherapy	49
Progressive evolution of secondary aquatic adaptation in hippos and cetaceans	48
Structural insights into cyanobacterial RuBisCO assembly coordinated by two chaperones Raf1 and RbcX	47
A Ctnnb1 enhancer regulates neocortical neurogenesis by controlling the abundance of intermediate progenitors	47
Single-cell analysis reveals differences among iNKT cells colonizing peripheral organs and identifies Klf2 as a key gene for iNKT emigration	47
Structures of adenosine receptor A2BR bound to endogenous and synthetic agonists	46
In vivo treatment of tyrosinaemia with hypercompact Cas12f1	45
Functional profiling of stage-specific proteome and translational transition across human pre-implantation embryo development at a single-cell resolution	44
MTSS1 curtails lung adenocarcinoma immune evasion by promoting AIP4-mediated PD-L1 monoubiquitination and lysosomal degradation	43
Author Correction: Reprogramming of palmitic acid induced by dephosphorylation of ACOX1 promotes β-catenin palmitoylation to drive colorectal cancer progression	43
Biogenesis of Rab14-positive endosome buds at Golgi–endosome contacts by the RhoBTB3–SHIP164–Vps26B complex	42
Publisher Correction: TET2 is required to suppress mTORC1 signaling through urea cycle with therapeutic potential	42
Author Correction: Ketogenic diet-produced β-hydroxybutyric acid accumulates brain GABA and increases GABA/glutamate ratio to inhibit epilepsy	41
Simultaneous de novo calling and phasing of genetic variants at chromosome-scale using NanoStrand-seq	40
Human zygotic genome activation is initiated from paternal genome	39
Deciphering the role of immunoglobulin secreting malignant lineages in the invasive frontiers of small cell lung cancer by scRNA-seq and spatial transcriptomics analysis	38
Truncated PARP1 mediates ADP-ribosylation of RNA polymerase III for apoptosis	38
Decoding the pathogenesis of Diamond–Blackfan anemia using single-cell RNA-seq	38
DdCBE-mediated mitochondrial base editing in human 3PN embryos	38
Extracellular vesicles transfer chromatin-like structures that induce non-mutational dysfunction of p53 in bone marrow stem cells	37
Distinct phases of adult microglia proliferation: a Myc-mediated early phase and a Tnfaip3-mediated late phase	37
Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication	37
Author Correction: Postsynaptic lncRNA Sera/Pkm2 pathway orchestrates the transition from social competition to rank by remodeling the neural ensemble in mPFC	37
A broader neutralizing antibody against all the current VOCs and VOIs targets unique epitope of SARS-CoV-2 RBD	37
Precision modeling of mitochondrial diseases in zebrafish via DdCBE-mediated mtDNA base editing	37
Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages	36
Publisher Correction: Single-cell atlas of keratoconus corneas revealed aberrant transcriptional signatures and implicated mechanical stretch as a trigger for keratoconus pathogenesis	36
Structural and functional insights into the helicase protein E5 of Mpox virus	36
Sca1 marks a reserve endothelial progenitor population that preferentially expand after injury	35
Safety and feasibility of anti-CD19 CAR T cells expressing inducible IL-7 and CCL19 in patients with relapsed or refractory large B-cell lymphoma	35
Bi-allelic variants in human WDR63 cause male infertility via abnormal inner dynein arms assembly	35
Single-cell and spatial proteo-transcriptomic profiling reveals immune infiltration heterogeneity associated with neuroendocrine features in small cell lung cancer	35
A bipotential organoid model of respiratory epithelium recapitulates high infectivity of SARS-CoV-2 Omicron variant	34
Screening of potent neutralizing antibodies against SARS-CoV-2 using convalescent patients-derived phage-display libraries	34
Dynamic 3D genome reorganization during development and metabolic stress of the porcine liver	34
Spatio-temporal landscape of mouse epididymal cells and specific mitochondria-rich segments defined by large-scale single-cell RNA-seq	34
A spatiotemporal transcriptomic atlas of mouse placentation	33
Structure basis for the modulation of CXC chemokine receptor 3 by antagonist AMG487	33
Sperm epigenetic alterations contribute to inter- and transgenerational effects of paternal exposure to long-term psychological stress via evading offspring embryonic reprogramming	33
Hypercompact TnpB and truncated TnpB systems enable efficient genome editing in vitro and in vivo	33
Ketogenic diet-produced β-hydroxybutyric acid accumulates brain GABA and increases GABA/glutamate ratio to inhibit epilepsy	32
Structural insights into neurokinin 3 receptor activation by endogenous and analogue peptide agonists	32
SARS-CoV-2 nucleocapsid protein impairs stress granule formation to promote viral replication	32
Efficacy and safety of novel multifunctional M10 CAR-T cells in HIV-1-infected patients: a phase I, multicenter, single-arm, open-label study	31
KRAS(G12D) can be targeted by potent inhibitors via formation of salt bridge	31
Structural insights into the activation of somatostatin receptor 2 by cyclic SST analogues	31

A positive mechanobiological feedback loop controls bistable switching of cardiac fibroblast phenotype	31
Microplastics dampen the self-renewal of hematopoietic stem cells by disrupting the gut microbiota-hypoxanthine-Wnt axis	31
CD36+ cancer-associated fibroblasts provide immunosuppressive microenvironment for hepatocellular carcinoma via secretion of macrophage migration inhibitory factor	31
Molecular mechanism of prolactin-releasing peptide recognition and signaling via its G protein-coupled receptor	31
DEPDC5 protects CD8+ T cells from ferroptosis by limiting mTORC1-mediated purine catabolism	30
Chimeric antigen receptor T cells self-neutralizing IL6 storm in patients with hematologic malignancy	30
Metagenome-genome-wide association studies reveal human genetic impact on the oral microbiome	30
Structural insights into human brain–gut peptide cholecystokinin receptors	30
40 Hz light flickering facilitates the glymphatic flow via adenosine signaling in mice	30
Molecular mechanisms of urate transport by the native human URAT1 and its inhibition by anti-gout drugs	29
Cell signaling and transcriptional regulation of osteoblast lineage commitment, differentiation, bone formation, and homeostasis	29
CCL2-mediated inflammatory pathogenesis underlies high myopia-related anxiety	29
Autologous transplantation of thecal stem cells restores ovarian function in nonhuman primates	29
SARS-CoV-2 Spike protein S2 subunit modulates γ-secretase and enhances amyloid-β production in COVID-19 neuropathy	29
SARS-CoV-2 exploits host DGAT and ADRP for efficient replication	29
A decrease in Flavonifractor plautii and its product, phytosphingosine, predisposes individuals with phlegm-dampness constitution to metabolic disorders	28
Programmable broad-spectrum resistance to bacterial blight using targeted insertion in rice	28
Characterization of respiratory microbial dysbiosis in hospitalized COVID-19 patients	28
Mechanisms of ligand recognition and activation of melanin-concentrating hormone receptors	28
Treatment of allergic eosinophilic asthma through engineered IL-5-anchored chimeric antigen receptor T cells	28
Comprehensive investigations revealed consistent pathophysiological alterations after vaccination with COVID-19 vaccines	28
Elimination of Cas9-dependent off-targeting of adenine base editor by using TALE to separately guide deaminase to target sites	27
Author Correction: Single-cell and spatial proteo-transcriptomic profiling reveals immune infiltration heterogeneity associated with neuroendocrine features in small cell lung cancer	27
Cryo-EM structure of PML RBCC dimer reveals CC-mediated octopus-like nuclear body assembly mechanism	27
Single-cell multi-omics analysis of lineage development and spatial organization in the human fetal cerebellum	27
Historical loss weakens competitive behavior by remodeling ventral hippocampal dynamics	27
Structural insights into human ABCD3-mediated peroxisomal acyl-CoA translocation	27
Derivation of transgene-free bat induced pluripotent stem cells amenable to chimera formation in mice, pigs, and chicks	27
Specialized Tfh cell subsets driving type-1 and type-2 humoral responses in lymphoid tissue	27
Systematic profiling of SARS-CoV-2-specific IgG responses elicited by an inactivated virus vaccine identifies peptides and proteins for predicting vaccination efficacy	27
Bacterial toxins induce non-canonical migracytosis to aggravate acute inflammation	26
RNA cytidine acetyltransferase NAT10 maintains T cell pathogenicity in inflammatory bowel disease	25
Structural and molecular basis of the epistasis effect in enhanced affinity between SARS-CoV-2 KP.3 and ACE2	25
The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum	25
Author Correction: TMEM151A variants cause paroxysmal kinesigenic dyskinesia	24
Precision modeling of mitochondrial disease in rats via DdCBE-mediated mtDNA editing	24
Artificial intelligence defines protein-based classification of thyroid nodules	24
Author Correction: A genetically encoded ratiometric indicator for tryptophan	24
Structural characterization reveals substrate recognition by the taurine transporter TauT	24
Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies	24
Prediction of overall survival in stage II and III colon cancer through machine learning of rapidly-acquired proteomics	24
LncRNA TubAR complexes with TUBB4A and TUBA1A to promote microtubule assembly and maintain myelination	24
Self-recruited neutrophils trigger over-activated innate immune response and phenotypic change of cardiomyocytes in fulminant viral myocarditis	24
Interplay between ADP-ribosyltransferases and essential cell signaling pathways controls cellular responses	23
Surface translocation of ACE2 and TMPRSS2 upon TLR4/7/8 activation is required for SARS-CoV-2 infection in circulating monocytes	23
Humoral responses in naive or SARS-CoV-2 experienced individuals vaccinated with an inactivated vaccine	23
Proximity editing to identify RNAs in phase-separated RNA binding protein condensates	23
Identification of oligosaccharyltransferase as a host target for inhibition of SARS-CoV-2 and its variants	23
Structural insights into assembly of human mitochondrial translocase TOM complex	23
Genome-wide association study of COVID-19 severity among the Chinese population	23
Identification of a rare Gli1+ progenitor cell population contributing to liver regeneration during chronic injury	22
Single-cell profiling reveals molecular basis of malignant phenotypes and tumor microenvironments in small bowel adenocarcinomas	22
Author Correction: Artificial intelligence defines protein-based classification of thyroid nodules	22
Resetting histone modifications during human prenatal germline development	22
Neutralization of Omicron BA.4/BA.5 and BA.2.75 by booster vaccination or BA.2 breakthrough infection sera	21
The activation mechanism and antibody binding mode for orphan GPR20	21
Neutralization of Omicron XBB.1 by booster vaccination with BA.4/5 monovalent mRNA vaccine	21
High-precision mapping reveals rare N6-deoxyadenosine methylation in the mammalian genome	21
Cell type-specific NRBF2 orchestrates autophagic flux and adult hippocampal neurogenesis in chronic stress-induced depression	21
In-cell structural insight into the stability of sperm microtubule doublet	21
Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation	21
Enhanced inflammation and suppressed adaptive immunity in COVID-19 with prolonged RNA shedding	21
Designed allosteric protein logic	21
Structural insight into how WDR4 promotes the tRNA N7-methylguanosine methyltransferase activity of METTL1	20
Integrated proteogenomic characterization of ampullary adenocarcinoma	20
Epigenetic editing alleviates Angelman syndrome phenotype in mice by unsilencing paternal Ube3a	20
Mediator MED23 controls oligodendrogenesis and myelination by modulating Sp1/P300-directed gene programs	20
New mouse genetic model of breast cancer from IKKα defects in dendritic cells revealed by single-cell RNA sequencing	20
Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2	20
Mapping crossover events of mouse meiotic recombination by restriction fragment ligation-based Refresh-seq	20
A virus-derived microRNA-like small RNA serves as a serum biomarker to prioritize the COVID-19 patients at high risk of developing severe disease	20
WTAP–VIRMA counteracts dsDNA binding of the m6A writer METTL3–METTL14 complex and maintains N6-adenosine methylation activity	20
Resistance mechanisms of SARS-CoV-2 3CLpro to the non-covalent inhibitor WU-04	20
Impact of SARS-CoV-2 envelope protein mutations on the pathogenicity of Omicron XBB	20
Single-cell transcriptomics reveals intestinal cell heterogeneity and identifies Ep300 as a potential therapeutic target in mice with acute liver failure	19
2,3-Butanediol synthesis from glucose supplies NADH for elimination of toxic acetate produced during overflow metabolism	19
ScRNA-seq revealed the kinetic of nasopharyngeal immune responses in asymptomatic COVID-19 carriers	19
Inhibiting hedgehog signal by a patched-1 antibody	19
MAPK13 phosphorylates PHGDH and promotes its degradation via chaperone-mediated autophagy during liver injury	19
Author Correction: SGF29 nuclear condensates reinforce cellular aging	19

Developing an erythrocyte‒MHC-I conjugate for cancer treatment	19
Cryo-EM structure of SETD2/Set2 methyltransferase bound to a nucleosome containing oncohistone mutations	19
SARS-CoV-2 vaccination-infection pattern imprints and diversifies T cell differentiation and neutralizing response against Omicron subvariants	19
SGF29 nuclear condensates reinforce cellular aging	18
Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome	18
RBBP6 maintains glioblastoma stem cells through CPSF3-dependent alternative polyadenylation	18
CRISPR signal conductor 2.0 for redirecting cellular information flow	18
Treating a type 2 diabetic patient with impaired pancreatic islet function by personalized endoderm stem cell-derived islet tissue	18
Molecular mechanism of substrate recognition by folate transporter SLC19A1	18
Single-cell multiomics analysis reveals regulatory programs in clear cell renal cell carcinoma	18
Integration of 3D bioprinting and multi-algorithm machine learning identified glioma susceptibilities and microenvironment characteristics	17
High-throughput and high-sensitivity full-length single-cell RNA-seq analysis on third-generation sequencing platform	17
Increased morbidity of obese mice infected with mouse-adapted SARS-CoV-2	17
Lineage-specific regulatory changes in hypertrophic cardiomyopathy unraveled by single-nucleus RNA-seq and spatial transcriptomics	17
TET2 is required to suppress mTORC1 signaling through urea cycle with therapeutic potential	17
Structure of the full-length human Pannexin1 channel and insights into its role in pyroptosis	17
Single-cell spatiotemporal analysis of the lungs reveals Slamf9+ macrophages involved in viral clearance and inflammation resolution	17
Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with Gs proteins	17
TMC6 functions as a GPCR-like receptor to sense noxious heat via Gαq signaling	17
Single-cell RNA sequencing identifies an Il1rn+/Trem1+ macrophage subpopulation as a cellular target for mitigating the progression of thoracic aortic aneurysm and dissection	17
ALKBH3-dependent m1A demethylation of Aurora A mRNA inhibits ciliogenesis	17
ShennongAlpha: an AI-driven sharing and collaboration platform for intelligent curation, acquisition, and translation of natural medicinal material knowledge	17
Cryo-EM structures of human TMEM120A and TMEM120B	16
VH-CH1 switch region-inserting multispecific antibody designs and their efficacy against SARS-CoV-2 in vitro and in vivo	16
Stem cell transplantation extends the reproductive life span of naturally aging cynomolgus monkeys	16
Potential of angiotensin II receptor blocker telmisartan in reducing mortality among hospitalized patients with COVID-19 compared with recommended drugs	16
Structural insights into cholesterol transport and hydrolase activity of a putative human RNA transport protein SIDT1	16
Treatment of SARS-CoV-2-induced pneumonia with NAD+ and NMN in two mouse models	16
TMEM151A variants cause paroxysmal kinesigenic dyskinesia	16
A genetically encoded ratiometric indicator for tryptophan	16
A positive feedback loop between SMAD3 and PINK1 in regulation of mitophagy	16
Mitochondrial base editor DdCBE causes substantial DNA off-target editing in nuclear genome of embryos	16
Heat shock protein DNAJA2 regulates transcription-coupled repair by triggering CSB degradation via chaperone-mediated autophagy	15
The RNA-binding protein LUC7L2 mediates MITA/STING intron retention to negatively regulate innate antiviral response	15
Author Correction: Calcium channel blocker amlodipine besylate therapy is associated with reduced case fatality rate of COVID-19 patients with hypertension	15
Functional comparison of SARS-CoV-2 with closely related pangolin and bat coronaviruses	15
Loss-of-function variants in human C12orf40 cause male infertility by blocking meiotic progression	15
Reduced sensitivity of SARS-CoV-2 Omicron variant to antibody neutralization elicited by booster vaccination	15
Structural basis for neutralization of an anicteric hepatitis associated echovirus by a potent neutralizing antibody	15
PROTAC for Bruton’s tyrosine kinase degradation alleviates inflammation in autoimmune diseases	15
IFRD1 promotes tumor cells “low-cost” survival under glutamine starvation via inhibiting histone H1.0 nucleophagy	15
Monitoring the promoter activity of long noncoding RNAs and stem cell differentiation through knock-in of sgRNA flanked by tRNA in an intron	15
Distinct BCR repertoires elicited by SARS-CoV-2 RBD and S vaccinations in mice	14
A trifunctional peptide broadly inhibits SARS-CoV-2 Delta and Omicron variants in hamsters	14
Single-cell dissection of remodeled inflammatory ecosystem in primary and metastatic gallbladder carcinoma	14
Author Correction: Molecular basis for Eaf3-mediated assembly of Rpd3S and NuA4	14
The Hippo pathway effector YAP inhibits HIF2 signaling and ccRCC tumor growth	14
Author Correction: Structure of the trypanosome paraflagellar rod and insights into non-planar motility of eukaryotic cells	14
PHF14 enhances DNA methylation of SMAD7 gene to promote TGF-β-driven lung adenocarcinoma metastasis	14
Critically short telomeres derepress retrotransposons to promote genome instability in embryonic stem cells	14
Author Correction: Host susceptibility and structural and immunological insight of S proteins of two SARS-CoV-2 closely related bat coronaviruses	14
Author Correction: Coronary vessels contribute to de novo endocardial cells in the endocardium-depleted heart	14
Extracellular vesicles mediate antibody-resistant transmission of SARS-CoV-2	14
Long-term and effective neutralization against omicron sublineages elicited by four platform COVID-19 vaccines as a booster dose	14
A pangolin-origin SARS-CoV-2-related coronavirus: infectivity, pathogenicity, and cross-protection by preexisting immunity	14
Molecular architecture and gating mechanisms of the Drosophila TRPA1 channel	14
Author Correction: Generation of permanent neonatal diabetes mellitus dogs with glucokinase point mutations through base editing	13
TPM4 condensates glycolytic enzymes and facilitates actin reorganization under hyperosmotic stress	13
Author Correction: Metformin potentiates nephrotoxicity by promoting NETosis in response to renal ferroptosis	13
Single-cell sequencing depicts tumor architecture and empowers clinical decision in metastatic conjunctival melanoma	13
TAZ is required for chondrogenesis and skeletal development	13
Author Correction: Regulation of hnRNPA1 by microRNAs controls the miR-18a-K-RAS axis in chemotherapy-resistant ovarian cancer	13
Generation of permanent neonatal diabetes mellitus dogs with glucokinase point mutations through base editing	13
Molecular architecture of monkeypox mature virus	13
Structural basis of connexin-36 gap junction channel inhibition	13
Multi-modal molecular determinants of clinically relevant osteoporosis subtypes	13
Author Correction: A single-cell atlas of liver metastases of colorectal cancer reveals reprogramming of the tumor microenvironment in response to preoperative chemotherapy	13
VAPB-mediated ER-targeting stabilizes IRS-1 signalosomes to regulate insulin/IGF signaling	13
Integrated compact regulators of protein activity enable control of signaling pathways and genome-editing in vivo	13
Recognition of antiepileptic brivaracetam by synaptic vesicle protein 2A	13
Transgenerational inheritance of diabetes susceptibility in male offspring with maternal androgen exposure	13
Fast and flexible profiling of chromatin accessibility and total RNA expression in single nuclei using Microwell-seq3	13
Host susceptibility and structural and immunological insight of S proteins of two SARS-CoV-2 closely related bat coronaviruses	12
Coronary vessels contribute to de novo endocardial cells in the endocardium-depleted heart	12
Targeting a chemo-induced adaptive signaling circuit confers therapeutic vulnerabilities in pancreatic cancer	12
Pharmacology of LRRK2 with type I and II kinase inhibitors revealed by cryo-EM	12
TMEM41B is an endoplasmic reticulum Ca2+ release channel maintaining naive T cell quiescence and responsiveness	12
Apaf-1 is an evolutionarily conserved DNA sensor that switches the cell fate between apoptosis and inflammation	12
From lipotoxicity to pan-lipotoxicity	12
Broad host tropism of ACE2-using MERS-related coronaviruses and determinants restricting viral recognition	12
Spatiotemporal single-cell architecture of gene expression in the Caenorhabditis elegans germ cells	12
TGF-β controls development of TCRγδ+CD8αα+ intestinal intraepithelial lymphocytes	12
The Cardamine enshiensis genome reveals whole genome duplication and insight into selenium hyperaccumulation and tolerance	12
Characterization of the landscape of the intratumoral microbiota reveals that Streptococcus anginosus increases the risk of gastric cancer initiation and progression	12
Multi-dimensional single-cell characterization revealed suppressive immune microenvironment in AFP-positive hepatocellular carcinoma	12
Potential cross-species transmission of highly pathogenic avian influenza H5 subtype (HPAI H5) viruses to humans calls for the development of H5-specific and universal influenza vaccines	11
Targeting SNRNP200-induced splicing dysregulation offers an immunotherapy opportunity for glycolytic triple-negative breast cancer	11
A live-cell image-based machine learning strategy for reducing variability in PSC differentiation systems	11
Integrated proteogenomic characterization of medullary thyroid carcinoma	11
Heterologous prime-boost immunizations with chimpanzee adenoviral vectors elicit potent and protective immunity against SARS-CoV-2 infection	11
A conditional protein diffusion model generates artificial programmable endonuclease sequences with enhanced activity	11
Generation of human blastocyst-like structures from pluripotent stem cells	11
CHD8 mutations increase gliogenesis to enlarge brain size in the nonhuman primate	11
Structure of the SWI/SNF complex bound to the nucleosome and insights into the functional modularity	11
Reprogramming an RNA-guided archaeal TnpB endonuclease for genome editing	11