OOIR: Observatory of International Research

Papers

(The H4-Index of npj Systems Biology and Applications is 19. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Sunset Yellow protects against oxidative damage and exhibits chemoprevention in chemically induced skin cancer model	60
Knowledge-based mechanistic modeling accurately predicts disease progression with gefitinib in EGFR-mutant lung adenocarcinoma	58
Measuring criticality in control of complex biological networks	47
Severe testing with high-dimensional omics data for enhancing biomedical scientific discovery	42
Transcriptome analysis of clock disrupted cancer cells reveals differential alternative splicing of cancer hallmarks genes	40
Data-driven modeling of core gene regulatory network underlying leukemogenesis in IDH mutant AML	35
Optimization of nutrient utilization efficiency and productivity for algal cultures under light and dark cycles using genome-scale model process control	32
Leveraging public AI tools to explore systems biology resources in mathematical modeling	32
Spatial computational modelling illuminates the role of the tumour microenvironment for treating glioblastoma with immunotherapies	31
Causality-aware graph neural networks for functional stratification and phenotype prediction at scale	30
Olfactory receptors contribute to progression of kidney fibrosis	29
Comprehensive molecular interaction map of TGFβ induced epithelial to mesenchymal transition in breast cancer	29
Quantitative cancer-immunity cycle modeling for predicting disease progression in advanced metastatic colorectal cancer	29
Classification of NSCLC subtypes using lung microbiome from resected tissue based on machine learning methods	26
Tissue-wide cell-specific proteogenomic modeling reveals novel candidate risk genes in autism spectrum disorders	24
Modelling HIV-1 control and remission	23
Understanding the role of toggle genes in chronic lymphocytic leukemia proliferation	21
Revisiting the evolution of bow-tie architecture in signaling networks	21
Author Correction: Computer modeling defines the system driving a constant current crucial for homeostasis in the mammalian cochlea by integrating unique ion transports	19