OOIR: Observatory of International Research

Papers

(The TQCC of npj Regenerative Medicine is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Author Correction: Chondrogenic differentiation induced by extracellular vesicles bound to a nanofibrous substrate	142
Allogeneic RPE cell suspension manufactured at scale demonstrating preclinical safety and efficacy led to IND approval	78
Combinatorial extracellular matrix tissue chips for optimizing mesenchymal stromal cell microenvironment and manufacturing	67
Supramolecular nanostructure mimics GDNF trophic effects in vitro on human dopaminergic neurons	66
Author Correction: The bright side of fibroblasts: molecular signature and regenerative cues in major organs	66
Micropattern-based nerve guidance conduit with hundreds of microchannels and stem cell recruitment for nerve regeneration	64
Proteomic profiling of iPSC and tissue-derived MSC secretomes reveal a global signature of inflammatory licensing	57
Biological study of skin wound treated with Alginate/Carboxymethyl cellulose/chorion membrane, diopside nanoparticles, and Botox A	52
The Warburg effect is necessary to promote glycosylation in the blastema during zebrafish tail regeneration	52
Skeletal muscle regeneration after extensive cryoinjury of caudal myomeres in adult zebrafish	46
Airway epithelial cell identity and plasticity are constrained by Sox2 during lung homeostasis, tissue regeneration, and in human disease	43
Implication of CXCR2-Src axis in the angiogenic and osteogenic effects of FP-TEB	43
Grafted hPSC-derived GABA-ergic interneurons regulate seizures and specific cognitive function in temporal lobe epilepsy	42
An engineered periosteum for efficient delivery of rhBMP-2 and mesenchymal progenitor cells during bone regeneration	41
Pain sensing neurons promote tissue regeneration in adult mice	41
The MRN complex maintains the biliary-derived hepatocytes in liver regeneration through ATR-Chk1 pathway	40
Cyclic pulsation stress promotes bone formation of tissue engineered laminae through the F-actin/YAP-1/β-Catenin signaling axis	39
Functional ProTracer identifies patterns of cell proliferation in tissues and underlying regulatory mechanisms	39
Modeling congenital cataract in vitro using patient-specific induced pluripotent stem cells	37
Infected wound repair correlates with collagen I induction and NOX2 activation by cold atmospheric plasma	35
Modulating the platelet-mediated innate foreign body response to affect in situ vascular tissue engineering outcomes	35
Bio-orthogonal crosslinking and hyaluronan facilitate transparent healing after treatment of deep corneal injuries with in situ-forming hydrogels	35
Exosome biopotentiated hydrogel restores damaged skeletal muscle in a porcine model of stress urinary incontinence	34
Exploiting in silico modelling to enhance translation of liver cell therapies from bench to bedside	32
Inflammation-suppressing cornea-in-a-syringe with anti-viral GF19 peptide promotes regeneration in HSV-1 infected rabbit corneas	32

Calorie restriction and rapamycin distinctly restore non-canonical ORF translation in the muscles of aging mice	32
Analysis of the early response to spinal cord injury identified a key role for mTORC1 signaling in the activation of neural stem progenitor cells	32
Comparison studies identify mesenchymal stromal cells with potent regenerative activity in osteoarthritis treatment	32
Harnessing bioengineered myeloid progenitors for precision immunotherapies	31
Scale up manufacturing approach for production of human induced pluripotent stem cell-derived islets using Vertical Wheel® bioreactors	30
MAP4Ks inhibition promotes retinal neuron regeneration from Müller glia in adult mice	29
Proteoglycan 4 (PRG4) treatment enhances wound closure and tissue regeneration	29
Stem cell-based therapy for COVID-19 and ARDS: a systematic review	28
A short dasatinib and quercetin treatment is sufficient to reinstate potent adult neuroregenesis in the aged killifish	27
Direct reprogramming of mouse fibroblasts into self-renewable alveolar epithelial-like cells	26
Hippo-Yap/Taz signalling in zebrafish regeneration	25
Leiomodin 2 neonatal dilated cardiomyopathy mutation results in altered actin gene signatures and cardiomyocyte dysfunction	25
BMP-2 functional polypeptides relieve osteolysis via bi-regulating bone formation and resorption coupled with macrophage polarization	24
Clinically relevant small-molecule promotes nerve repair and visual function recovery	24
Metformin accelerates zebrafish heart regeneration by inducing autophagy	24
Epimorphic regeneration in the mammalian tympanic membrane	23
Co-transplantation of pancreatic islets and microvascular fragments effectively restores normoglycemia in diabetic mice	23
Pluripotent stem cell-derived committed cardiac progenitors remuscularize damaged ischemic hearts and improve their function in pigs	23
Human adipose-derived stromal/stem cells expressing doublecortin improve cartilage repair in rabbits and monkeys	23
Immunomodulation by the combination of statin and matrix-bound nanovesicle enhances optic nerve regeneration	23
The specialist in regeneration—the Axolotl—a suitable model to study bone healing?	23
Transplantation of derivative retinal organoids from chemically induced pluripotent stem cells restored visual function	23
Ischemic tolerance and cardiac repair in the spiny mouse (Acomys)	22
Regeneration-specific promoter switching facilitates Mest expression in the mouse digit tip to modulate neutrophil response	22
A computational model reveals an early transient decrease in fiber cross-linking that unlocks adult regeneration	22
Macrophages in heterotopic ossification: from mechanisms to therapy	22
Sonic Hedgehog acts as a macrophage chemoattractant during regeneration of the gastric epithelium	22
Transgene-free direct conversion of murine fibroblasts into functional muscle stem cells	21
Endogenous tenocyte activation underlies the regenerative capacity of the adult zebrafish tendon	21
Immunomodulatory matrix-bound nanovesicles mitigate acute and chronic pristane-induced rheumatoid arthritis	21
Macrophage-based therapy for intervertebral disc herniation: preclinical proof-of-concept	21
Type I collagen and fibromodulin enhance the tenogenic phenotype of hASCs and their potential for tendon regeneration	20
Local BMP2 hydrogel therapy for robust bone regeneration in a porcine model of Legg-Calvé-Perthes disease	20
Development of an optogenetic gene sensitive to daylight and its implications in vision restoration	20
Author Correction: Patients seeking stem cell therapies—a prospective qualitative analysis from a Regenerative Medicine Consult Service	19
A STAT5-Smad3 dyad regulates adipogenic plasticity of visceral adipose mesenchymal stromal cells during chronic inflammation	19
Author Correction : SUPT4H1-edited stem cell therapy rescues neuronal dysfunction in a mouse model for Huntington’s disease	19
Preclinical efficacy and safety of AAVrh10-based plakophilin-2 gene therapy (LX2020) as a treatment for arrhythmogenic cardiomyopathy	19
Structural, angiogenic, and immune responses influencing myocardial regeneration: a glimpse into the crucible	19
Immune-mediated regeneration of cell-free vascular grafts in an ovine model	18
Author Correction: Capacitive interdigitated system of high osteoinductive/conductive performance for personalized acting-sensing implants	18
Differential activation of Ca2+ influx channels modulate stem cell potency, their proliferation/viability and tissue regeneration	18
Regeneration of tracheal neotissue in partially decellularized scaffolds	18
Dynamics of skeletal muscle-resident stem cells during myogenesis in fibrodysplasia ossificans progressiva	18
Newly regenerated axons via scaffolds promote sub-lesional reorganization and motor recovery with epidural electrical stimulation	18