OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Death Discovery is 51. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Regulatory role of PPAR in colorectal cancer	419
Age-associated microglial transcriptome leads to diminished immunogenicity and dysregulation of MCT4 and P2RY12/P2RY13 related functions	317
SAA3 deficiency exacerbates intestinal fibrosis in DSS-induced IBD mouse model	163
Retraction Note: LINC00355 induces gastric cancer proliferation and invasion through promoting ubiquitination of P53	160
Smac-mimetic enhances antitumor effect of standard chemotherapy in ovarian cancer models via Caspase 8-independent mechanism	155
Macrocarpal I induces immunogenic cell death and synergizes with immune checkpoint inhibition by targeting tubulin and PARP1 in colorectal cancer	152
Discoidin domain receptor inhibitor DDR1-IN-1 induces autophagy and necroptotic cell death in malignant peripheral nerve sheath tumor	123
Cell death in tumor microenvironment: an insight for exploiting novel therapeutic approaches	106
CircHIPK3 regulates fatty acid metabolism through miR-637/FASN axis to promote esophageal squamous cell carcinoma	99
Defective efferocytosis by aged macrophages promotes STING signaling mediated inflammatory liver injury	98
Mitochondrial metabolism and targeted treatment strategies in ischemic-induced acute kidney injury	95
Gadd45g initiates embryonic stem cell differentiation and inhibits breast cell carcinogenesis	90
Regulation of m6A modification on ferroptosis and its potential significance in radiosensitization	89
A positive feedback loop: RAD18-YAP-TGF-β between triple-negative breast cancer and macrophages regulates cancer stemness and progression	88
PSMC2/ITGA6 axis plays critical role in the development and progression of hepatocellular carcinoma	83
Helicobacter pylori reduces METTL14-mediated VAMP3 m6A modification and promotes the development of gastric cancer by regulating LC3C-mediated c-Met recycling	82
TMEM45A enhances palbociclib resistance and cellular glycolysis by activating AKT/mTOR signaling pathway in HR+ breast cancer	82
GILT stabilizes cofilin to promote the metastasis of prostate cancer	81
m6A methylation: a potential key player in understanding and treating COVID-2019 infection	80
Nr1d1 inhibition mitigates intermittent hypoxia-induced pulmonary hypertension via Dusp1-mediated Erk1/2 deactivation and mitochondrial fission attenuation	79
Elevated histone demethylase KDM5C increases recurrent miscarriage risk by preventing trophoblast proliferation and invasion	79
Hepatic TNFRSF12A promotes bile acid-induced hepatocyte pyroptosis through NFκB/Caspase-1/GSDMD signaling in cholestasis	79
Systemic tumor regression with synergy therapy: radiotherapy and CAR-T	74
Deptor protects against myocardial ischemia-reperfusion injury by regulating the mTOR signaling and autophagy	73
Infection of Helicobacter pylori contributes to the progression of gastric cancer through ferroptosis	72

METTL3 knockdown promotes temozolomide sensitivity of glioma stem cells via decreasing MGMT and APNG mRNA stability	71
Correction to: T cells in idiopathic pulmonary fibrosis: crucial but controversial	69
NMDARs antagonist MK801 suppresses LPS-induced apoptosis and mitochondrial dysfunction by regulating subunits of NMDARs via the CaM/CaMKII/ERK pathway	68
A regulatory network controlling ovarian granulosa cell death	64
Serine and one-carbon metabolism sustain non-melanoma skin cancer progression	63
Drosophila FGFR/Htl signaling shapes embryonic glia to phagocytose apoptotic neurons	63
The endocannabinoid system promotes hepatocyte progenitor cell proliferation and maturation by modulating cellular energetics	62
Correction to: NSUN2 alleviates doxorubicin-induced myocardial injury through Nrf2-mediated antioxidant stress	61
Silencing Notch4 promotes tumorigenesis and inhibits metastasis of triple-negative breast cancer via Nanog and Cdc42	61
Correction: Novel insights into the METTL3-METTL14 complex in musculoskeletal diseases	60
Correction: SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes	60
IRE1α RIDD activity induced under ER stress drives neuronal death by the degradation of 14-3-3 θ mRNA in cortical neurons during glucose deprivation	59
Antitumor effect of Melaleuca alternifolia essential oil and its main component terpinen-4-ol in combination with target therapy in melanoma models	58
Loss of PML nuclear bodies in familial amyotrophic lateral sclerosis-frontotemporal dementia	57
OASIS/CREB3L1 is a factor that responds to nuclear envelope stress	57
Epigenetic reprogramming promotes the antiviral action of IFNα in HBV-infected cells	57
Impairment of neuronal mitochondrial function by l-DOPA in the absence of oxygen-dependent auto-oxidation and oxidative cell damage	56
Nuclear transport maintenance of USP22-AR by Importin-7 promotes breast cancer progression	56
The spatiotemporal dynamics of spatially variable genes in developing mouse brain revealed by a novel computational scheme	55
LIF/LIFR oncogenic signaling is a novel therapeutic target in endometrial cancer	54
Correction: DCLK1 isoforms and aberrant Notch signaling in the regulation of human and murine colitis	53
Cutaneous squamous cell carcinoma-derived extracellular vesicles exert an oncogenic role by activating cancer-associated fibroblasts	53
CD5L deficiency attenuate acetaminophen-induced liver damage in mice via regulation of JNK and ERK signaling pathway	52
Pancreas morphogenesis and homeostasis depends on tightly regulated Zeb1 levels in epithelial cells	52
Combination therapy with HSP90 inhibitors and piperlongumine promotes ROS-mediated ER stress in colon cancer cells	52
The involvement of caspases in the process of nuclear removal during lens fiber cell differentiation	51
A master of all trades – linking retinoids to different signalling pathways through the multi-purpose receptor STRA6	51