OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Death Discovery is 58. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
USP22 regulates APL differentiation via PML-RARα stabilization and IFN repression	238
FNDC5 inhibits autophagy of bone marrow mesenchymal stem cells and promotes their survival after transplantation by downregulating Sp1	185
Transcriptional activation of PINK1 by MyoD1 mediates mitochondrial homeostasis to induce renal calcification in pediatric nephrolithiasis	178
Retraction Note to: Inhibition of TGF-β repairs spinal cord injury by attenuating EphrinB2 expressing through inducing miR-484 from fibroblast	167
N-ethylmaleimide-sensitive factor elicits a neuroprotection against ischemic neuronal injury by restoring autophagic/lysosomal dysfunction	166
Exosomal circRNAs: key modulators in breast cancer progression	164
Matrix metalloproteinase-10 promotes kidney fibrosis by transactivating β-catenin signaling	155
POLE2 promotes osteosarcoma progression by enhancing the stability of CD44	152
An mTOR and DNA-PK dual inhibitor CC-115 hinders non-small cell lung cancer cell growth	120
AIM2 regulates autophagy to mitigate oxidative stress in aged mice with acute liver injury	115
Silencing Notch4 promotes tumorigenesis and inhibits metastasis of triple-negative breast cancer via Nanog and Cdc42	113
MiR-148a deletion protects from bone loss in physiological and estrogen-deficient mice by targeting NRP1	110
Long non-coding RNA-encoded micropeptides: functions, mechanisms and implications	110
Mammalian target of rapamycin inhibition protects glioma cells from temozolomide-induced cell death	109
Downregulation of macrophage migration inhibitory factor attenuates NLRP3 inflammasome mediated pyroptosis in sepsis-induced AKI	106
Stem cell-derived intestinal organoids: a novel modality for IBD	100
ERR-activated GPR35 promotes immune infiltration level of macrophages in gastric cancer tissues	100
SMAD3 and FTO are involved in miR-5581-3p-mediated inhibition of cell migration and proliferation in bladder cancer	97
CircHIPK3 regulates fatty acid metabolism through miR-637/FASN axis to promote esophageal squamous cell carcinoma	92
AXL tyrosine kinase inhibitor TP-0903 induces ROS trigger neuroblastoma cell apoptosis via targeting the miR-335-3p/DKK1 expression	91
Hippo pathway and NLRP3-driven NETosis in macrophages: Mechanisms of viral pneumoniaaggravation	91
RNA-mediated inhibition of mitochondrial SHMT2 impairs cancer cell proliferation	89
Radiobiological characterisation of a 28 MeV proton beam delivered by the MC-40 cyclotron	88
Mitochondrial metabolic reprogramming in colorectal cancer: mechanisms of resistance and future clinical interventions	85
LIMA1 links the E3 ubiquitin ligase RNF40 to lipid metabolism	85

The plasticity of epithelial cells and its potential in the induced differentiation of gastric cancer	84
The role of ankyrin repeat-containing proteins in epigenetic and transcriptional regulation	83
Melanoma innervation, noradrenaline and cancer progression in zebrafish xenograft model	83
LMNB2-mediated high PD-L1 transcription triggers the immune escape of hepatocellular carcinoma	83
The endocannabinoid system promotes hepatocyte progenitor cell proliferation and maturation by modulating cellular energetics	81
Absence of Rnf126 causes male infertility with multiple morphological abnormalities of the sperm flagella	80
Targeting NAD+: is it a common strategy to delay heart aging?	80
Grb2 interacts with necrosome components and is involved in rasfonin-induced necroptosis	80
CircMETTL3-156aa reshapes the glycolytic metabolism of macrophages to promote M1 polarization and induce cytokine storms in sHLH	79
Tissue microenvironment induces tissue specificity of ILC2	78
Mobilization and activation of tumor-infiltrating dendritic cells inhibits lymph node metastasis in intrahepatic cholangiocarcinoma	78
Cellular senescence of renal tubular epithelial cells in acute kidney injury	77
Therapeutic targeting of STING-IL6/STAT3 axis to inhibit osteoclastic niche formation and breast cancer bone metastasis	76
Lipids associated with autophagy: mechanisms and therapeutic targets	76
PLOD3 contributes to HER-2 therapy resistance in gastric cancer through FoxO3/Survivin pathway	76
DUB3/KLF4 combats tumor growth and chemoresistance in hepatocellular carcinoma	74
Senescence as a dictator of patient outcomes and therapeutic efficacies in human gastric cancer	72
Diverse functions of NLRP3 inflammasome in PANoptosis and diseases	71
Exploring necroptosis: mechanistic analysis and antitumor potential of nanomaterials	69
A positive feedback loop: RAD18-YAP-TGF-β between triple-negative breast cancer and macrophages regulates cancer stemness and progression	68
STING agonists trigger monocyte death via apoptosis, pyroptosis, caspase-8 activation and mitochondrial dysfunction	67
New insights into constitutive neutrophil death	67
Therapeutic potential of voltage-dependent potassium channel subtype 1.3 blockade in alleviating macrophage-related renal inflammation and fibrogenesis	66
The pathological role of damaged organelles in renal tubular epithelial cells in the progression of acute kidney injury	66
USP32 deubiquitinase: cellular functions, regulatory mechanisms, and potential as a cancer therapy target	66
Elevated histone demethylase KDM5C increases recurrent miscarriage risk by preventing trophoblast proliferation and invasion	65
Lipid peroxidation in osteoarthritis: focusing on 4-hydroxynonenal, malondialdehyde, and ferroptosis	64
GILT stabilizes cofilin to promote the metastasis of prostate cancer	64
The role of lncRNA-mediated ceRNA regulatory networks in pancreatic cancer	63
IDO1 facilitates esophageal carcinoma progression by driving the direct binding of NF-κB and CXCL10	63
MEK inhibitors increase the mortality rate in mice with LPS-induced inflammation through IL-12-NO signaling	62
Targeting Txnip-mediated metabolic reprogramming has therapeutic potential for osteoarthritis	62
CD95 gene deletion may reduce clonogenic growth and invasiveness of human glioblastoma cells in a CD95 ligand-independent manner	62
NRF2 transcriptionally regulates Caspase-11 expression to activate HMGB1 release by Autophagy-deficient hepatocytes	58