Cell Death Discovery

Papers
(The TQCC of Cell Death Discovery is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
FNDC5 inhibits autophagy of bone marrow mesenchymal stem cells and promotes their survival after transplantation by downregulating Sp1250
Transcriptional activation of PINK1 by MyoD1 mediates mitochondrial homeostasis to induce renal calcification in pediatric nephrolithiasis223
Retraction Note to: Inhibition of TGF-β repairs spinal cord injury by attenuating EphrinB2 expressing through inducing miR-484 from fibroblast194
Exploring necroptosis: mechanistic analysis and antitumor potential of nanomaterials179
DUB3/KLF4 combats tumor growth and chemoresistance in hepatocellular carcinoma178
Therapeutic targeting of STING-IL6/STAT3 axis to inhibit osteoclastic niche formation and breast cancer bone metastasis172
Therapeutic potential of voltage-dependent potassium channel subtype 1.3 blockade in alleviating macrophage-related renal inflammation and fibrogenesis162
GILT stabilizes cofilin to promote the metastasis of prostate cancer161
POLE2 promotes osteosarcoma progression by enhancing the stability of CD44122
Matrix metalloproteinase-10 promotes kidney fibrosis by transactivating β-catenin signaling122
An mTOR and DNA-PK dual inhibitor CC-115 hinders non-small cell lung cancer cell growth121
SMAD3 and FTO are involved in miR-5581-3p-mediated inhibition of cell migration and proliferation in bladder cancer117
AXL tyrosine kinase inhibitor TP-0903 induces ROS trigger neuroblastoma cell apoptosis via targeting the miR-335-3p/DKK1 expression115
RNA-mediated inhibition of mitochondrial SHMT2 impairs cancer cell proliferation114
Radiobiological characterisation of a 28 MeV proton beam delivered by the MC-40 cyclotron104
Melanoma innervation, noradrenaline and cancer progression in zebrafish xenograft model102
Elevated histone demethylase KDM5C increases recurrent miscarriage risk by preventing trophoblast proliferation and invasion101
Mammalian target of rapamycin inhibition protects glioma cells from temozolomide-induced cell death100
Absence of Rnf126 causes male infertility with multiple morphological abnormalities of the sperm flagella97
The role of ankyrin repeat-containing proteins in epigenetic and transcriptional regulation97
Tissue microenvironment induces tissue specificity of ILC293
Targeting NAD+: is it a common strategy to delay heart aging?93
ERR-activated GPR35 promotes immune infiltration level of macrophages in gastric cancer tissues93
A positive feedback loop: RAD18-YAP-TGF-β between triple-negative breast cancer and macrophages regulates cancer stemness and progression90
Hippo pathway and NLRP3-driven NETosis in macrophages: Mechanisms of viral pneumoniaaggravation88
The plasticity of epithelial cells and its potential in the induced differentiation of gastric cancer87
Grb2 interacts with necrosome components and is involved in rasfonin-induced necroptosis85
LIMA1 links the E3 ubiquitin ligase RNF40 to lipid metabolism85
IDO1 facilitates esophageal carcinoma progression by driving the direct binding of NF-κB and CXCL1085
Mobilization and activation of tumor-infiltrating dendritic cells inhibits lymph node metastasis in intrahepatic cholangiocarcinoma84
Silencing Notch4 promotes tumorigenesis and inhibits metastasis of triple-negative breast cancer via Nanog and Cdc4284
USP32 deubiquitinase: cellular functions, regulatory mechanisms, and potential as a cancer therapy target83
LMNB2-mediated high PD-L1 transcription triggers the immune escape of hepatocellular carcinoma83
Metformin protects retinal ganglion cells in a preclinical model of retinal ischemia/reperfusion injury and stabilizes visual field in diabetic patients with glaucoma82
CircMETTL3-156aa reshapes the glycolytic metabolism of macrophages to promote M1 polarization and induce cytokine storms in sHLH82
The endocannabinoid system promotes hepatocyte progenitor cell proliferation and maturation by modulating cellular energetics82
N-ethylmaleimide-sensitive factor elicits a neuroprotection against ischemic neuronal injury by restoring autophagic/lysosomal dysfunction81
STING agonists trigger monocyte death via apoptosis, pyroptosis, caspase-8 activation and mitochondrial dysfunction79
N6-methyladenosine: a key regulator in ocular disease mechanisms and treatment78
MiR-148a deletion protects from bone loss in physiological and estrogen-deficient mice by targeting NRP177
The pathological role of damaged organelles in renal tubular epithelial cells in the progression of acute kidney injury76
Long non-coding RNA-encoded micropeptides: functions, mechanisms and implications74
PLOD3 contributes to HER-2 therapy resistance in gastric cancer through FoxO3/Survivin pathway71
Lipid peroxidation in osteoarthritis: focusing on 4-hydroxynonenal, malondialdehyde, and ferroptosis70
Stem cell-derived intestinal organoids: a novel modality for IBD70
Cellular senescence of renal tubular epithelial cells in acute kidney injury70
CircHIPK3 regulates fatty acid metabolism through miR-637/FASN axis to promote esophageal squamous cell carcinoma69
Diverse functions of NLRP3 inflammasome in PANoptosis and diseases69
The role of lncRNA-mediated ceRNA regulatory networks in pancreatic cancer69
Downregulation of macrophage migration inhibitory factor attenuates NLRP3 inflammasome mediated pyroptosis in sepsis-induced AKI68
Exosomal circRNAs: key modulators in breast cancer progression67
New insights into constitutive neutrophil death67
Mitochondrial metabolic reprogramming in colorectal cancer: mechanisms of resistance and future clinical interventions67
AIM2 regulates autophagy to mitigate oxidative stress in aged mice with acute liver injury65
USP22 regulates APL differentiation via PML-RARα stabilization and IFN repression65
Lipids associated with autophagy: mechanisms and therapeutic targets64
Senescence as a dictator of patient outcomes and therapeutic efficacies in human gastric cancer64
CD95 gene deletion may reduce clonogenic growth and invasiveness of human glioblastoma cells in a CD95 ligand-independent manner61
Smurf2-induced degradation of SMAD2 causes inhibition of hair follicle stem cell differentiation60
Correction: Autophagy in hepatic ischemia–reperfusion injury59
TRPS1 regulates the opposite effect of progesterone via RANKL in endometrial carcinoma and breast carcinoma58
COVID-19 related neurological manifestations in Parkinson’s disease: has ferroptosis been a suspect?58
JMJD2C mediates the MDM2/p53/IL5RA axis to promote CDDP resistance in uveal melanoma57
BRD7 suppresses tumor chemosensitivity to CHK1 inhibitors by inhibiting USP1-mediated deubiquitination of CHK157
Neddylation inhibition induces DNA double-strand breaks, hampering tumor growth in vivo, and promotes radiosensitivity in PAX3–FOXO1 rhabdomyosarcoma57
Long non-coding RNA MAFG-AS1 promotes proliferation and metastasis of breast cancer by modulating STC2 pathway57
Thapsigargin triggers a non-apoptotic, caspase-independent programmed cell death in basophilic leukaemia cells56
APOE4 promotes nigral tau hyperphosphorylation through cholesterol in atherosclerosis56
The EIF4EBP1 gene encoding 4EBP1 is transcriptionally upregulated by MYC and linked to shorter survival in medulloblastoma56
Exosomal miR-122-5p from tubular cells ameliorates renal interstitial fibrosis by regulating fibroblasts via HIF-1α56
Modulation of stress granules by lobeline increases cell death in hypoxia and impacts the ability of glioblastoma cells to secrete extracellular vesicles56
Hexamethylene amiloride induces lysosome-mediated cell death in multiple myeloma through transcription factor E356
Heat shock protein 90α reduces CD8+ T cell exhaustion in acute lung injury induced by lipopolysaccharide56
Fexofenadine protects against osteoarthritis by targeting Smad2 and STAT1 to enhance anabolism and binding cPLA2 to inhibit catabolism56
YAP is required for prostate development, regeneration, and prostate stem cell function55
From mechanisms to markers: role of pyroptosis in revolutionizing thyroid cancer care55
Long noncoding RNA SNHG1 silencing accelerates hepatocyte-like cell differentiation of bone marrow-derived mesenchymal stem cells to alleviate cirrhosis via the microRNA-15a/SMURF1/UVRAG axis55
MEK inhibitors increase the mortality rate in mice with LPS-induced inflammation through IL-12-NO signaling55
Epirubicin induces cardiotoxicity through disrupting ATP6V0A2-dependent lysosomal acidification and triggering ferroptosis in cardiomyocytes54
Exploring the metabolic signaling network of GFPT in cancer54
NRF2 transcriptionally regulates Caspase-11 expression to activate HMGB1 release by Autophagy-deficient hepatocytes54
Loss of Ripk3 attenuated neutrophil accumulation in a lipopolysaccharide-induced zebrafish inflammatory model54
Vitamin D receptor attenuate ischemia-reperfusion kidney injury via inhibiting ATF453
Repurposing proteasome inhibitors for improved treatment of triple-negative breast cancer52
LINC complex protein nesprin-2 has pro-apoptotic activity via Bcl-2 family proteins52
Methylation in cornea and corneal diseases: a systematic review52
MYC inhibition reprograms tumor immune microenvironment by recruiting T lymphocytes and activating the CD40/CD40L system in osteosarcoma52
Targeting Txnip-mediated metabolic reprogramming has therapeutic potential for osteoarthritis52
MiR-134-5p inhibits the malignant phenotypes of osteosarcoma via ITGB1/MMP2/PI3K/Akt pathway51
Fosinopril mediates antitumor efficacy by inducing GSDME-dependent pyroptosis in NSCLC50
Polyploidy mitigates the impact of DNA damage while simultaneously bearing its burden50
Shift work promotes adipogenesis via cortisol-dependent downregulation of EGR3-HDAC6 pathway50
The EZH2-H3K27me3 axis modulates aberrant transcription and apoptosis in cyclophosphamide-induced ovarian granulosa cell injury50
LncRNA in tumorigenesis of non-small-cell lung cancer: From bench to bedside49
VDR and deubiquitination control neuronal oxidative stress and microglial inflammation in Parkinson’s disease49
LncRNA XIST accelerates burn wound healing by promoting M2 macrophage polarization through targeting IL-33 via miR-19b48
Immunotherapy for autoimmune encephalitis48
Gemcitabine elaidate and ONC201 combination therapy for inhibiting pancreatic cancer in a KRAS mutated syngeneic mouse model48
Comprehensive analysis of cellular metrics: From proliferation to mitochondrial membrane potential and cell death in a single sample47
Novel FOXM1 inhibitor STL001 sensitizes human cancers to a broad-spectrum of cancer therapies47
Enhancer reprogramming: critical roles in cancer and promising therapeutic strategies47
Emerging mechanisms of pyroptosis and its therapeutic strategy in cancer47
Circadian rhythm regulates the function of immune cells and participates in the development of tumors47
Tumor suppressor p53 mediates interleukin-6 expression to enable cancer cell evasion of genotoxic stress47
IL-8 activates fibroblasts to promote the invasion of HNSCC cells via STAT3-MMP147
Metabolic reprogramming in melanoma therapy46
Targeting metastasis-initiating cancer stem cells in gastric cancer with leukaemia inhibitory factor45
Correction: FTO promotes tumour proliferation in bladder cancer via the FTO/miR-576/CDK6 axis in an m6A-dependent manner45
Rapid iPSC-derived neuromuscular junction model uncovers motor neuron dominance in amyotrophic lateral sclerosis cytopathy45
DSE inhibits melanoma progression by regulating tumor immune cell infiltration and VCAN44
Increased efficacy of PARP inhibitors against cisplatin-sensitive and -resistant ovarian cancer cells mediated via ATR and ATM inhibition44
LIGHT deficiency attenuates acute kidney disease development in an in vivo experimental renal ischemia and reperfusion injury model44
Anti-CCL2 therapy reduces oxygen toxicity to the immature lung43
PGD2 displays distinct effects in diffuse large B-cell lymphoma depending on different concentrations43
Gastrointestinal acute radiation syndrome: current knowledge and perspectives43
CREB5 promotes nodal metastasis of cervical cancer by regulation of APLN-induced lymphangiogenesis42
LncRNA LYPLAL1-DT screening from type 2 diabetes with macrovascular complication contributes protective effects on human umbilical vein endothelial cells via regulating the miR-204-5p/SIRT1 axis42
SOX17-mediated MALAT1-miR-199a-HIF1α axis confers sensitivity in esophageal squamous cell carcinoma cells to radiotherapy42
An evolutionarily conserved role for separase in the regulation of nuclear lamins42
Correction to: Microfluidic deep mutational scanning of the human executioner caspases reveals differences in structure and regulation42
RETRACTED ARTICLE: MIR600HG sponges miR-125a-5p to regulate glycometabolism and cisplatin resistance of oral squamous cell carcinoma cells via mediating RNF4442
MED15 is upregulated by HIF-2α and promotes proliferation and metastasis in clear cell renal cell carcinoma via activation of SREBP-dependent fatty acid synthesis41
Mechanisms of ferroptosis and targeted therapeutic approaches in urological malignancies41
UCK2 promotes intrahepatic cholangiocarcinoma progression and desensitizes cisplatin treatment by PI3K/AKT/mTOR/autophagic axis41
Overcoming apoptotic resistance afforded by Bcl-2 in lymphoid tumor cells: a critical role for dexamethasone41
CAPG is a novel biomarker for early gastric cancer and is involved in the Wnt/β-catenin signaling pathway40
NEDD8-conjugating enzyme E2s: critical targets for cancer therapy40
RASAL2 regulates the cell cycle and cyclin D1 expression through PI3K/AKT signalling in prostate tumorigenesis40
TRIM29 hypermethylation drives esophageal cancer progression via suppression of ZNF75040
IRGM/Irgm1 increases autophagy to inhibit activation of NLRP3 inflammasome in inflammatory injury induced acute liver failure40
LEADR, a p63 target, dampens interferon signalling in bladder cancer40
PPA1 promotes oxidative phosphorylation and malignant progression of colorectal cancer under glucose restriction via AMPK/ULK1/FUNDC1-mediated mitophagy39
Simultaneous blockade of VEGF-B and IL-17A ameliorated diabetic kidney disease by reducing ectopic lipid deposition and alleviating inflammation response39
Mechanical stiffness promotes skin fibrosis through Piezo1-mediated arginine and proline metabolism39
FGFR inhibition as a new therapeutic strategy to sensitize glioblastoma stem cells to tumor treating fields39
Deletion in RMST lncRNA impairs hypothalamic neuronal development in a human stem cell-based model of Kallmann Syndrome39
Circular RNA hsa_circ_0001846 facilitates the malignant behaviors of pancreatic cancer by sponging miR-204-3p and upregulating KRAS expression38
ESRP1-driven alternative splicing of CLSTN1 inhibits the metastasis of gastric cancer38
Correction: Tim-3 protects against cisplatin nephrotoxicity by inhibiting NF-κB-mediated inflammation38
Tumors cells with mismatch repair deficiency induce hyperactivation of pyroptosis resistant to cell membrane damage but are more sensitive to co-treatment of IFN-γ and TNF-α to PANoptosis38
Knockdown of METTL16 disrupts learning and memory by reducing the stability of MAT2A mRNA38
hMOF induces cisplatin resistance of ovarian cancer by regulating the stability and expression of MDM238
The potential role of hydrogen sulfide in cancer cell apoptosis38
Developing novel Lin28 inhibitors by computer aided drug design38
Fatty acid amide hydrolase drives adult mammary gland development by promoting luminal cell differentiation38
N4BP1 functions as a dimerization-dependent linear ubiquitin reader which regulates TNF signalling38
Dopaminergic neurodegeneration in the substantia nigra is associated with olfactory dysfunction in mice models of Parkinson’s disease38
Oleanolic acid combined with aspirin plays antitumor roles in colorectal cancer via the Akt/NFκB/IκBα/COX2 pathway37
Patient-derived zebrafish xenografts of uveal melanoma reveal ferroptosis as a drug target37
BAP1 inactivation promotes lactate production by leveraging the subcellular localization of LDHA in melanoma37
Nesprin-2 contains BH3-like motifs that can promote cell death37
Tp53 haploinsufficiency is involved in hotspot mutations and cytoskeletal remodeling in gefitinib-induced drug-resistant EGFRL858R-lung cancer mice37
CRISPR/Cas9 screening identifies SUV39H2 as a key regulator of oHSV-1 resistance in oral squamous cell carcinoma36
IFNγ regulates ferroptosis in KFs by inhibiting the expression of SPOCD1 through DNMT3A36
Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner36
Different types of cell death and their shift in shaping disease36
Standardized assays to monitor drug sensitivity in hematologic cancers36
Organoids and organs-on-chips: insights into predicting the efficacy of systemic treatment in colorectal cancer36
Metal-polyphenol-network coated R612F nanoparticles reduce drug resistance in hepatocellular carcinoma by inhibiting stress granules36
Antisense lncRNA NNT-AS1 promoted esophageal squamous cell carcinoma progression by regulating its sense gene NNT expression35
USP18 deubiquitinates and stabilizes SOX9 to promote the stemness and malignant progression of glioblastoma35
Uveitic glaucoma-like features in Yap conditional knockout mice35
PARP4 deficiency enhances sensitivity to ATM inhibitor by impairing DNA damage repair in melanoma35
Nucleophosmin 1 cooperates with BRD4 to facilitate c-Myc transcription to promote prostate cancer progression35
Correction: Heparanase promotes endothelial-to-mesenchymal transition in diabetic glomerular endothelial cells through mediating ERK signaling35
Downregulation of KLF10 contributes to the regeneration of survived renal tubular cells in cisplatin-induced acute kidney injury via ZBTB7A-KLF10-PTEN axis35
Author Correction: Gelatine nanostructured lipid carrier encapsulated FGF15 inhibits autophagy and improves recovery in spinal cord injury35
Maternal linoleic acid-rich diet ameliorates bilirubin neurotoxicity in offspring mice35
ERBB3 influences the ferroptosis pathway via modulation of lipid peroxidation and GSH synthesis in gastric cancer35
Integrated stress response is involved in the 24(S)-hydroxycholesterol-induced unconventional cell death mechanism35
A bibliometric analysis of ferroptosis, necroptosis, pyroptosis, and cuproptosis in cancer from 2012 to 202234
Roflumilast inhibits tumor growth and migration in STK11/LKB1 deficient pancreatic cancer34
circ_0004140 promotes LUAD tumor progression and immune resistance through circ_0004140/miR-1184/CCL22 axis34
Serum amyloid protein A in inflammatory bowel disease: from bench to bedside34
Synergistic mechanism between the endoplasmic reticulum and mitochondria and their crosstalk with other organelles34
SOX2 and OCT4 mediate radiation and drug resistance in pancreatic tumor organoids34
hnRNP A1 inhibits colorectal cancer tumorigenesis and progression by regulating fatty acid metabolism and RNA stability33
NAT10-mediated upregulation of GAS5 facilitates immune cell infiltration in non-small cell lung cancer via the MYBBP1A-p53/IRF1/type I interferon signaling axis33
Tissue-resident Klebsiella quasipneumoniae contributes to progression of idiopathic pulmonary fibrosis by triggering macrophages mitophagy in mice33
METTL14 promotes prostate tumorigenesis by inhibiting THBS1 via an m6A-YTHDF2-dependent mechanism33
Bellidifolin ameliorates isoprenaline-induced cardiac hypertrophy by the Nox4/ROS signalling pathway through inhibiting BRD433
The cancer/testis antigen HORMAD1 mediates epithelial–mesenchymal transition to promote tumor growth and metastasis by activating the Wnt/β-catenin signaling pathway in lung cancer33
Tumor-derived extracellular vesicles inhibit HGF/c-Met and EGF/EGFR pathways to accelerate the radiosensitivity of nasopharyngeal carcinoma cells via microRNA-142-5p delivery33
PLK1 inhibition promotes apoptosis and DNA damage in glioma stem cells by regulating the nuclear translocation of YBX133
Saikosaponin‑D triggers cancer cell death by targeting the PIM1/c-Myc axis to reprogram oncogenic alternative splicing32
Mesenchymal stem cell-derived extracellular vesicles transfer miR-598 to inhibit the growth and metastasis of non-small-cell lung cancer by targeting THBS232
Exploiting dysregulated iron homeostasis to eradicate persistent high-grade serous ovarian cancer32
Targeting the redox-programmed cell death axis in breast cancer: from molecular mechanisms to therapeutic resistance32
Long noncoding RNA profiling unveils LINC00960 as unfavorable prognostic biomarker promoting triple negative breast cancer progression32
Hsa_circ_0007967 promotes gastric cancer proliferation through the miR-411-5p/MAML3 axis32
Circular RNAs and mammalian follicular development: current insights and future prospects—an updated review32
CaMKIV mediates spine growth deficiency of hippocampal neurons by regulation of EGR3/BDNF signal axis in congenital hypothyroidism32
Inhibition of lysosomal TRPML1 channel eliminates breast cancer stem cells by triggering ferroptosis31
The malignancy of chordomas is enhanced via a circTLK1/miR-16-5p/Smad3 positive feedback axis31
NRG1/PDGFC loop between fibroblasts and cancer cells drives paclitaxel resistance via ferroptosis suppression in breast cancer31
UBAP2L promotes gastric cancer metastasis by activating NF-κB through PI3K/AKT pathway31
IL-1β promotes esophageal squamous cell carcinoma growth and metastasis through FOXO3A by activating the PI3K/AKT pathway31
TAZ promotes osteogenic differentiation of mesenchymal stem cells line C3H10T1/2, murine multi-lineage cells lines C2C12, and MEFs induced by BMP931
Interplay between genes and social environment: from epigenetics to precision medicine31
The LTB4-BLT1 axis attenuates influenza-induced lung inflammation by suppressing NLRP3 activation31
The miRNA and PD-1/PD-L1 signaling axis: an arsenal of immunotherapeutic targets against lung cancer30
MiR-146a-5p deficiency in extracellular vesicles of glioma-associated macrophages promotes epithelial-mesenchymal transition through the NF-κB signaling pathway30
CERS6 promotes esophageal squamous cell carcinoma proliferation by increasing the stability of RPN130
4-aminopyridine attenuates inflammation and apoptosis and increases angiogenesis to promote skin regeneration following a burn injury in mice30
Decoding MUC1 and AR axis in a radiation-induced neuroendocrine prostate cancer cell-subpopulation unveils novel therapeutic targets30
AMPK-induced novel phosphorylation of RUNX1 inhibits STAT3 activation and overcome imatinib resistance in chronic myelogenous leukemia (CML) subjects30
RRM1 promotes homologous recombination and radio/chemo-sensitivity via enhancing USP11 and E2F1-mediated RAD51AP1 transcription30
Lysophosphatidic acid exerts protective effects on HEI-OC1 cells against cytotoxicity of cisplatin by decreasing apoptosis, excessive autophagy, and accumulation of ROS30
Role of Sox9 in BPD and its effects on the Wnt/β-catenin pathway and AEC-II differentiation30
NSD1 supports cell growth and regulates autophagy in HPV-negative head and neck squamous cell carcinoma30
TRAF6 triggers Mycobacterium-infected host autophagy through Rab7 ubiquitination30
NOXA exacerbates endoplasmic-reticulum-stress-induced intervertebral disc degeneration by activating apoptosis and ECM degradation30
Novel meriolin derivatives activate the mitochondrial apoptosis pathway in the presence of antiapoptotic Bcl-230
Abl depletion via autophagy mediates the beneficial effects of quercetin against Alzheimer pathology across species30
Organoid modeling meets cancers of female reproductive tract30
Oncogenic microRNA-181d binding to OGT contributes to resistance of ovarian cancer cells to cisplatin29
Inhibition of acetyl-CoA carboxylase impaired tubulin palmitoylation and induced spindle abnormalities29
Myeloid PTEN loss affects the therapeutic response by promoting stress granule assembly and impairing phagocytosis by macrophages in breast cancer29
Insights on the crosstalk among different cell death mechanisms29
Ferroptosis: Emerging mechanisms, biological function, and therapeutic potential in cancer and inflammation29
Hypoxia-induced epigenetic regulation of miR-485-3p promotes stemness and chemoresistance in pancreatic ductal adenocarcinoma via SLC7A11-mediated ferroptosis29
Inhibition of RIPK1 by ZJU-37 promotes oligodendrocyte progenitor proliferation and remyelination via NF-κB pathway29
The trigger for pancreatic disease: NLRP3 inflammasome29
High-dose-androgen-induced autophagic cell death to suppress the Enzalutamide-resistant prostate cancer growth via altering the circRNA-BCL2/miRNA-198/AMBRA1 signaling29
Aging aggravated liver ischemia and reperfusion injury by promoting oxidized mtDNA mediated-macrophage pyroptosis through acetylated MCU-dependent calcium uptake29
N6-methyladenosine (m6A) writer METTL5 represses the ferroptosis and antitumor immunity of gastric cancer28
Human myeloid differentiation by BMP4 signaling through the VDR pathway in acute myeloid leukemia28
METTL3-mediated deficiency of lncRNA HAR1A drives non-small cell lung cancer growth and metastasis by promoting ANXA2 stabilization28
Repositioning Lomitapide to block ZDHHC5-dependant palmitoylation on SSTR5 leads to anti-proliferation effect in preclinical pancreatic cancer models28
Effects of astrocytic PKM2 gene deletion on neuronal death following traumatic brain injury28
Cuproptosis and cuproptosis-related cell death and genes: mechanistic links to spermatogenic cell death28
A comprehensive review of human trophoblast fusion models: recent developments and challenges28
Pre-clinical safety and therapeutic efficacy of a plant-based alkaloid in a human colon cancer xenograft model28
A miR-34a-guided, tRNAiMet-derived, piR_019752-like fragment (tRiMetF31) suppresses migration and angiogenesis of breast cancer cells via targeting PFKFB328
BZW2 promotes malignant progression in lung adenocarcinoma through enhancing the ubiquitination and degradation of GSK3β28
MiR-130a-3p regulates FUNDC1-mediated mitophagy by targeting GJA1 in myocardial ischemia/reperfusion injury28
Emerging roles of ferroptosis-related miRNAs in tumor metastasis28
Diabetes impairs fracture healing through Foxo1 mediated disruption of ciliogenesis28
MiR-140-3p regulates axonal motor protein KIF5A and contributes to axonal transport degeneration in SMA28
Functions and mechanisms of non-histone post-translational modifications in cancer progression28
Targeting ANXA7/LAMP5-mTOR axis attenuates spinal cord injury by inhibiting neuronal apoptosis via enhancing autophagy in mice28
A new advanced cellular model of functional cholinergic-like neurons developed by reprogramming the human SH-SY5Y neuroblastoma cell line28
RBM17 promotes hepatocellular carcinoma progression by regulating lipid metabolism and immune microenvironment: implications for therapeutic targeting27
Gas6 in chronic liver disease—a novel blood-based biomarker for liver fibrosis27
Targeting IL8 as a sequential therapy strategy to overcome chemotherapy resistance in advanced gastric cancer27
Rsk2 inhibition induces an aneuploid post-mitotic arrest of cell cycle progression in osteosarcoma cells27
NCOA7 inhibits renal cancer progression by inducing autophagy and lipid metabolism through V-ATPase interaction27
Correction: Oligomeric states of ASC specks regulate inflammatory responses by inflammasome in the extracellular space27
Targeting iron regulatory protein 2 (IRP2) to disrupt iron metabolism enhances radiosensitivity through mitochondrial dysfunction in breast cancer cells27
KDM4C silencing inhibits cell migration and enhances radiosensitivity by inducing CXCL2 transcription in hepatocellular carcinoma27
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