Cell Death Discovery

Article	Citations
Regulatory role of PPAR in colorectal cancer	419
Age-associated microglial transcriptome leads to diminished immunogenicity and dysregulation of MCT4 and P2RY12/P2RY13 related functions	317
SAA3 deficiency exacerbates intestinal fibrosis in DSS-induced IBD mouse model	163
Retraction Note: LINC00355 induces gastric cancer proliferation and invasion through promoting ubiquitination of P53	160
Smac-mimetic enhances antitumor effect of standard chemotherapy in ovarian cancer models via Caspase 8-independent mechanism	155
Macrocarpal I induces immunogenic cell death and synergizes with immune checkpoint inhibition by targeting tubulin and PARP1 in colorectal cancer	152
Discoidin domain receptor inhibitor DDR1-IN-1 induces autophagy and necroptotic cell death in malignant peripheral nerve sheath tumor	123
Cell death in tumor microenvironment: an insight for exploiting novel therapeutic approaches	106
CircHIPK3 regulates fatty acid metabolism through miR-637/FASN axis to promote esophageal squamous cell carcinoma	99
Defective efferocytosis by aged macrophages promotes STING signaling mediated inflammatory liver injury	98
Mitochondrial metabolism and targeted treatment strategies in ischemic-induced acute kidney injury	95
Gadd45g initiates embryonic stem cell differentiation and inhibits breast cell carcinogenesis	90
Regulation of m6A modification on ferroptosis and its potential significance in radiosensitization	89
A positive feedback loop: RAD18-YAP-TGF-β between triple-negative breast cancer and macrophages regulates cancer stemness and progression	88
PSMC2/ITGA6 axis plays critical role in the development and progression of hepatocellular carcinoma	83
TMEM45A enhances palbociclib resistance and cellular glycolysis by activating AKT/mTOR signaling pathway in HR+ breast cancer	82
Helicobacter pylori reduces METTL14-mediated VAMP3 m6A modification and promotes the development of gastric cancer by regulating LC3C-mediated c-Met recycling	82
GILT stabilizes cofilin to promote the metastasis of prostate cancer	81
m6A methylation: a potential key player in understanding and treating COVID-2019 infection	80
Elevated histone demethylase KDM5C increases recurrent miscarriage risk by preventing trophoblast proliferation and invasion	79
Hepatic TNFRSF12A promotes bile acid-induced hepatocyte pyroptosis through NFκB/Caspase-1/GSDMD signaling in cholestasis	79
Nr1d1 inhibition mitigates intermittent hypoxia-induced pulmonary hypertension via Dusp1-mediated Erk1/2 deactivation and mitochondrial fission attenuation	79
Systemic tumor regression with synergy therapy: radiotherapy and CAR-T	74
Deptor protects against myocardial ischemia-reperfusion injury by regulating the mTOR signaling and autophagy	73
Infection of Helicobacter pylori contributes to the progression of gastric cancer through ferroptosis	72

METTL3 knockdown promotes temozolomide sensitivity of glioma stem cells via decreasing MGMT and APNG mRNA stability	71
Correction to: T cells in idiopathic pulmonary fibrosis: crucial but controversial	69
NMDARs antagonist MK801 suppresses LPS-induced apoptosis and mitochondrial dysfunction by regulating subunits of NMDARs via the CaM/CaMKII/ERK pathway	68
A regulatory network controlling ovarian granulosa cell death	64
Serine and one-carbon metabolism sustain non-melanoma skin cancer progression	63
Drosophila FGFR/Htl signaling shapes embryonic glia to phagocytose apoptotic neurons	63
The endocannabinoid system promotes hepatocyte progenitor cell proliferation and maturation by modulating cellular energetics	62
Correction to: NSUN2 alleviates doxorubicin-induced myocardial injury through Nrf2-mediated antioxidant stress	61
Silencing Notch4 promotes tumorigenesis and inhibits metastasis of triple-negative breast cancer via Nanog and Cdc42	61
Correction: SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes	60
Correction: Novel insights into the METTL3-METTL14 complex in musculoskeletal diseases	60
IRE1α RIDD activity induced under ER stress drives neuronal death by the degradation of 14-3-3 θ mRNA in cortical neurons during glucose deprivation	59
Antitumor effect of Melaleuca alternifolia essential oil and its main component terpinen-4-ol in combination with target therapy in melanoma models	58
OASIS/CREB3L1 is a factor that responds to nuclear envelope stress	57
Epigenetic reprogramming promotes the antiviral action of IFNα in HBV-infected cells	57
Loss of PML nuclear bodies in familial amyotrophic lateral sclerosis-frontotemporal dementia	57
Impairment of neuronal mitochondrial function by l-DOPA in the absence of oxygen-dependent auto-oxidation and oxidative cell damage	56
Nuclear transport maintenance of USP22-AR by Importin-7 promotes breast cancer progression	56
The spatiotemporal dynamics of spatially variable genes in developing mouse brain revealed by a novel computational scheme	55
LIF/LIFR oncogenic signaling is a novel therapeutic target in endometrial cancer	54
Correction: DCLK1 isoforms and aberrant Notch signaling in the regulation of human and murine colitis	53
Cutaneous squamous cell carcinoma-derived extracellular vesicles exert an oncogenic role by activating cancer-associated fibroblasts	53
Pancreas morphogenesis and homeostasis depends on tightly regulated Zeb1 levels in epithelial cells	52
Combination therapy with HSP90 inhibitors and piperlongumine promotes ROS-mediated ER stress in colon cancer cells	52
CD5L deficiency attenuate acetaminophen-induced liver damage in mice via regulation of JNK and ERK signaling pathway	52
A master of all trades – linking retinoids to different signalling pathways through the multi-purpose receptor STRA6	51
The involvement of caspases in the process of nuclear removal during lens fiber cell differentiation	51
The C-terminal HSP90 inhibitor NCT-58 kills trastuzumab-resistant breast cancer stem-like cells	50
METTL9-SLC7A11 axis promotes hepatocellular carcinoma progression through ferroptosis inhibition	50
Synergistic antitumor efficacy of aspirin plus lenvatinib in hepatocellular carcinoma via regulating of diverse signaling pathways	50
Impairment of μ-calpain activation by rhTNFR:Fc reduces severe burn-induced membrane disruption in the heart	50
Correction: CircPVT1 promotes gallbladder cancer growth by sponging miR-339-3p and regulates MCL-1 expression	49
A novel DSP zebrafish model reveals training- and drug-induced modulation of arrhythmogenic cardiomyopathy phenotypes	48
A novel circular RNA, circMAML3, promotes tumor progression of prostate cancer by regulating miR-665/MAPK8IP2 axis	48
Squaramides enhance NLRP3 inflammasome activation by lowering intracellular potassium	48
MUC1-C is a target of salinomycin in inducing ferroptosis of cancer stem cells	48
Mammalian target of rapamycin inhibition protects glioma cells from temozolomide-induced cell death	48
Cathelicidin hCAP18/LL-37 promotes cell proliferation and suppresses antitumor activity of 1,25(OH)2D3 in hepatocellular carcinoma	48
Induction of apoptosis and autosis in cardiomyocytes by the combination of homocysteine and copper via NOX-mediated p62 expression	47
Downregulation of macrophage migration inhibitory factor attenuates NLRP3 inflammasome mediated pyroptosis in sepsis-induced AKI	47
LncRNA XR_596701 protects H9c2 cells against intermittent hypoxia-induced injury through regulation of the miR-344b-5p/FAIM3 axis	47
Targeting KCa3.1 channels to overcome erlotinib resistance in non-small cell lung cancer cells	46
Cholesterol metabolism and colorectal cancer: the plot thickens	46
Serine to proline mutation at position 341 of MYOC impairs trabecular meshwork function by causing autophagy deregulation	45
m6A methyltransferase KIAA1429 acts as an oncogenic factor in colorectal cancer by regulating SIRT1 in an m6A-dependent manner	45
Modulation of tumor microenvironment by targeting histone acetylation in bladder cancer	45
Electrical pulse stimulation parameters modulate N2a neuronal differentiation	45
Eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) expression in glioblastoma is driven by ETS1- and MYBL2-dependent transcriptional activation	45
DUB3/KLF4 combats tumor growth and chemoresistance in hepatocellular carcinoma	44
ALYREF-JunD-SLC7A5 axis promotes pancreatic ductal adenocarcinoma progression through epitranscriptome-metabolism reprogramming and immune evasion	44

Correction to: Implication of human endogenous retrovirus W family envelope in hepatocellular carcinoma promotes MEK/ERK-mediated metastatic invasiveness and doxorubicin resistance	44
Sympathetic nervous signaling dictates prostate cancer progression	44
Aggregability of the SQSTM1/p62-based aggresome-like induced structures determines the sensitivity to parthanatos	44
Ac-DEVD-CHO (caspase-3/DEVDase inhibitor) suppresses self-incompatibility–induced programmed cell death in the pollen tubes of petunia (Petunia hybrida E. Vilm.)	44
Protein expression of nucleolar protein 12 in the retina and its implication in protection of retina from UV irradiation damage	43
Hypoxia induced exosomal Circ-ZNF609 promotes pre-metastatic niche formation and cancer progression via miR-150-5p/VEGFA and HuR/ZO-1 axes in esophageal squamous cell carcinoma	43
PLEKHM2 deficiency induces impaired mitochondrial clearance and elevated ROS levels in human iPSC-derived cardiomyocytes	43
Regulation of HNRNP family by post-translational modifications in cancer	43
USP22 regulates APL differentiation via PML-RARα stabilization and IFN repression	43
Hypoxic preconditioning accelerates the healing of ischemic intestinal injury by activating HIF-1α/PPARα pathway-mediated fatty acid oxidation	42
POLE2 promotes osteosarcoma progression by enhancing the stability of CD44	42
miR-218-5p and doxorubicin combination enhances anticancer activity in breast cancer cells through Parkin-dependent mitophagy inhibition	42
Glycolysis-mTORC1 crosstalk drives proliferation of patient-derived endometrial cancer spheroid cells with ALDH activity	42
Enhancers in T Cell development and malignant lesions	41
METTL14 promotes neuroblastoma formation by inhibiting YWHAH via an m6A-YTHDF1-dependent mechanism	41
NAP1L1 regulates BIRC2 ubiquitination modification via E3 ubiquitin ligase UBR4 and hence determines hepatocellular carcinoma progression	41
Molecular profiling of a bladder cancer with very high tumour mutational burden	40
Tspan protein family: focusing on the occurrence, progression, and treatment of cancer	40
Improving the power of drug toxicity measurements by quantitative nuclei imaging	40
miRNA-7145-cuedc2 axis controls hematopoiesis through JAK1/STAT3 signaling pathway	39
LINC01342 silencing upregulates microRNA-508-5p to inhibit progression of lung cancer by reducing cysteine-rich secretory protein 3	39
N-ethylmaleimide-sensitive factor elicits a neuroprotection against ischemic neuronal injury by restoring autophagic/lysosomal dysfunction	39
EHHADH deficiency regulates pexophagy and accelerates tubulointerstitial injury in diabetic kidney disease	38
N6-methyladenosine (m6A) methyltransferase KIAA1429 accelerates the gefitinib resistance of non-small-cell lung cancer	38
Cathepsin B prevents cell death by fragmentation and destruction of pathological amyloid fibrils	38
H2S protects hippocampal neurons against hypoxia-reoxygenation injury by promoting RhoA phosphorylation at Ser188	38
ERR-activated GPR35 promotes immune infiltration level of macrophages in gastric cancer tissues	38
“Recent Advances in Cancer Research” Bern, November 4-5, 2022	38
New insights into constitutive neutrophil death	37
Syk inhibitor attenuates lupus in FcγRIIb−/− mice through the Inhibition of DNA extracellular traps from macrophages and neutrophils via p38MAPK-dependent pathway	37
One-carbon metabolism is distinct metabolic signature for proliferative intermediate exhausted T cells of ICB-resistant cancer patients	37
Promising prognostic value of Transglutaminase type 2 and its correlation with tumor-infiltrating immune cells in skin cutaneous melanoma	36
TAF2, within the TFIID complex, regulates the expression of a subset of protein-coding genes	36
N6-isopentenyladenosine induces cell death through necroptosis in human glioblastoma cells	36
CircRFWD3 promotes HNSCC metastasis by modulating miR-27a/b/PPARγ signaling	36
circDHTKD1 promotes lymphatic metastasis of bladder cancer by upregulating CXCL5	36
PKA inhibition kills l-asparaginase-resistant leukemic cells from relapsed acute lymphoblastic leukemia patients	36
Vascular derived endothelin receptor A controls endothelin-induced retinal ganglion cell death	36
Interaction between m6A methylation and noncoding RNA in glioma	35
Importance score of SARS-CoV-2 genome predicts the death risk of COVID-19	35
LIMA1 links the E3 ubiquitin ligase RNF40 to lipid metabolism	35
Cysteamine exerts in vitro antiviral activity against the SARS-CoV-2 Delta and Omicron variants	35
Mechanism of motoneuronal and pyramidal cell death in amyotrophic lateral sclerosis and its potential therapeutic modulation	35
An mTOR and DNA-PK dual inhibitor CC-115 hinders non-small cell lung cancer cell growth	35
MTA1 aggravates experimental colitis in mice by promoting transcription factor HIF1A and up-regulating AQP4 expression	35
Small molecule targeting FOXM1 DNA binding domain exhibits anti-tumor activity in ovarian cancer	35
JAK2 gene knockout inhibits corneal allograft rejection in mice by regulating dendritic cell-induced T cell immune tolerance	35
Peroxiredoxin I and II as novel therapeutic molecular targets in cervical cancer treatment through regulation of endoplasmic reticulum stress induced by bleomycin	35
FTO promotes clear cell renal cell carcinoma progression via upregulation of PDK1 through an m6A dependent pathway	34
HIF-1 inactivation empowers HIF-2 to drive hypoxia adaptation in aggressive forms of medulloblastoma	34
Inhibition of PKC-δ retards kidney fibrosis via inhibiting cGAS-STING signaling pathway in mice	34
Correction: Exogenous carbon monoxide promotes GPX4-dependent ferroptosis through ROS/GSK3β axis in non-small cell lung cancer	34
CCL11 released by GSDMD-mediated macrophage pyroptosis regulates angiogenesis after hindlimb ischemia	34
Mobilization and activation of tumor-infiltrating dendritic cells inhibits lymph node metastasis in intrahepatic cholangiocarcinoma	34
Platelet proteome reveals features of cell death, antiviral response and viral replication in covid-19	34
Human-specific gene CT47 blocks PRMT5 degradation to lead to meiosis arrest	34
PTBP1 protects Y RNA from cleavage leading to its apoptosis-specific degradation	34
Grb2 interacts with necrosome components and is involved in rasfonin-induced necroptosis	34
Correction: miR548ai antagonism attenuates exosome-induced endothelial cell dysfunction	34
Peds1 deficiency in zebrafish results in myeloid cell apoptosis and exacerbated inflammation	33
Retraction Note to: Inhibition of TGF-β repairs spinal cord injury by attenuating EphrinB2 expressing through inducing miR-484 from fibroblast	33
Premature senescence is regulated by crosstalk among TFEB, the autophagy lysosomal pathway and ROS derived from damaged mitochondria in NaAsO2-exposed auditory cells	33
Elucidation of an mTORC2-PKC-NRF2 pathway that sustains the ATF4 stress response and identification of Sirt5 as a key ATF4 effector	33
Transcription factor Foxp1 stimulates angiogenesis in adult rats after myocardial infarction	33
Transcriptional activation of PINK1 by MyoD1 mediates mitochondrial homeostasis to induce renal calcification in pediatric nephrolithiasis	32
Inhibition of mTOR signaling protects human glioma cells from hypoxia-induced cell death in an autophagy-independent manner	32
CircMETTL3-156aa reshapes the glycolytic metabolism of macrophages to promote M1 polarization and induce cytokine storms in sHLH	32
Annexin A2 plays a key role in protecting against cisplatin-induced AKI through β-catenin/TFEB pathway	32
The combination of temozolomide and perifosine synergistically inhibit glioblastoma by impeding DNA repair and inducing apoptosis	32
PDCL2 is essential for spermiogenesis and male fertility in mice	32
Proteomic and functional profiling of platelet-derived extracellular vesicles released under physiological or tumor-associated conditions	32
Pyruvate carboxylase promotes malignant transformation of papillary thyroid carcinoma and reduces iodine uptake	32
Multifaceted mitochondrial as a novel therapeutic target in dry eye: insights and interventions	32
DDX17 promotes the growth and metastasis of lung adenocarcinoma	32
TRIB3 inhibition by palbociclib sensitizes prostate cancer to ferroptosis via downregulating SOX2/SLC7A11 expression	32
Cellular senescence in ischemia/reperfusion injury	32
Indole-3-carbinol in vitro antiviral activity against SARS-Cov-2 virus and in vivo toxicity	31
Necroptosis-mediated HMGB1 secretion of keratinocytes as a key step for inflammation development in contact hypersensitivity	31
Lipids associated with autophagy: mechanisms and therapeutic targets	31
Correction: Silencing circFTO inhibits malignant phenotype through modulating DUSP4 expression in clear cell renal cell carcinoma	31

Tgf-β1 transcriptionally promotes 90K expression: possible implications for cancer progression	31
The oncogenic axis YAP/MYC/EZH2 impairs PTEN tumor suppression activity enhancing lung tumorigenicity	31
Microfluidic deep mutational scanning of the human executioner caspases reveals differences in structure and regulation	31
Somatic CG6015 mediates cyst stem cell maintenance and germline stem cell differentiation via EGFR signaling in Drosophila testes	30
The dual role of ferroptosis in anthracycline-based chemotherapy includes reducing resistance and increasing toxicity	30
Inhibitor of DNA binding 2 (Id2) mediates microtubule polymerization in the brain by regulating αK40 acetylation of α-tubulin	30
FBXL10 promotes EMT and metastasis of breast cancer cells via regulating the acetylation and transcriptional activity of SNAI1	30
Lysine-specific demethylase 1 inhibition enhances autophagy and attenuates early-stage post-spinal cord injury apoptosis	30
The NONRATT023402.2/rno-miR-3065-5p/NGFR axis affects levodopa-induced dyskinesia in a rat model of Parkinson’s disease	29
Downregulated developmental processes in the postnatal right ventricle under the influence of a volume overload	29
Co-amplification of CBX3 with EGFR or RAC1 in human cancers corroborated by a conserved genetic interaction among the genes	29
Direct protein–protein interaction between Npas4 and IPAS mutually inhibits their critical roles in neuronal cell survival and death	29
LncRNA-FKBP1C regulates muscle fiber type switching by affecting the stability of MYH1B	29
Long noncoding RNA SOX2OT promotes pancreatic cancer cell migration and invasion through destabilizing FUS protein via ubiquitination	29
FNDC5 inhibits autophagy of bone marrow mesenchymal stem cells and promotes their survival after transplantation by downregulating Sp1	29
Reprogramming of fatty acid metabolism: a hidden force regulating the occurrence and progression of cholangiocarcinoma	28
TM7SF2 regulates cell proliferation and apoptosis by activation of C-Raf/ERK pathway in cervical cancer	28
The impact of autophagy modulation on phenotype and survival of cardiac stromal cells under metabolic stress	28
SOSSB1 and SOSSB2 mutually regulate protein stability through competitive binding of SOSSA	28
Clonal haematopoiesis - a novel entity that modifies pathological processes in elderly	28
Tumor stem cell-derived exosomal microRNA-17-5p inhibits anti-tumor immunity in colorectal cancer via targeting SPOP and overexpressing PD-L1	28
Emerging roles of the Hedgehog signalling pathway in inflammatory bowel disease	28
Su(var)3-9 mediates age-dependent increase in H3K9 methylation on TDP-43 promoter triggering neurodegeneration	28
Stromal vascular fraction in the treatment of myositis	28
METTL3-mediated m6A methylation of C1qA regulates the Rituximab resistance of diffuse large B-cell lymphoma cells	28
The m6A demethylases FTO and ALKBH5 aggravate the malignant progression of nasopharyngeal carcinoma by coregulating ARHGAP35	28
Recombinant oncolytic adenovirus armed with CCL5, IL-12, and IFN-γ promotes CAR-T infiltration and proliferation in vivo to eradicate local and distal tumors	28
Coculture with macrophages alters ferroptosis susceptibility of triple-negative cancer cells	28
Effect of tumor-associated macrophages on lncRNA PURPL/miR-363/PDZD2 axis in osteosarcoma cells	28
IDO1 facilitates esophageal carcinoma progression by driving the direct binding of NF-κB and CXCL10	28
Aberrantly expressed Wnt5a in nurse-like cells drives resistance to Venetoclax in chronic lymphocytic leukemia	27
New approaches to targeted drug therapy of intracranial tumors	27
Correction: Sirt1 coordinates with ERα to regulate autophagy and adiposity	27
Correction to: A Bowman–Birk inhibitor induces apoptosis in human breast adenocarcinoma through mitochondrial impairment and oxidative damage following proteasome 20S inhibitio	27
SMAD3 and FTO are involved in miR-5581-3p-mediated inhibition of cell migration and proliferation in bladder cancer	27
The plasticity of epithelial cells and its potential in the induced differentiation of gastric cancer	27
Role of K63-linked ubiquitination in cancer	27
Correction to: Survival of midbrain dopamine neurons depends on the Bcl2 factor Mcl1	27
SOX on tumors, a comfort or a constraint?	27
Upregulation of Hsp27 via further inhibition of histone H2A ubiquitination confers protection against myocardial ischemia/reperfusion injury by promoting glycolysis and enhancing mitochondrial functio	27
Current insights into the expression and functions of tumor-derived immunoglobulins	27
Vitamin D sensitizes cervical cancer to radiation-induced apoptosis by inhibiting autophagy through degradation of Ambra1	27
Correction: Oleanolic acid enhances neural stem cell migration, proliferation and differentiation in vitro by inhibiting GSK3β activity	27
Correction: Glucose metabolism involved in PD-L1-mediated immune escape in the malignant kidney tumour microenvironment	27
Ammonium tetrathiomolybdate relieves oxidative stress in cisplatin-induced acute kidney injury via NRF2 signaling pathway	27
PLK1 maintains DNA methylation and cell viability by regulating phosphorylation-dependent UHRF1 protein stability	26
SIRT1 restoration enhances chondrocyte autophagy in osteoarthritis through PTEN-mediated EGFR ubiquitination	26
CEBPB-mediated upregulation of SERPINA1 promotes colorectal cancer progression by enhancing STAT3 signaling	26
B cell memory: from generation to reactivation: a multipronged defense wall against pathogens	26
Neuroprotection and axon regeneration by novel low-molecular-weight compounds through the modification of DOCK3 conformation	26
Roles and action mechanisms of bile acid-induced gastric intestinal metaplasia: a review	26
microRNA-27a-3p delivered by extracellular vesicles from glioblastoma cells induces M2 macrophage polarization via the EZH1/KDM3A/CTGF axis	26
Hyperglycemia-triggered ATF6-CHOP pathway aggravates acute inflammatory liver injury by β-catenin signaling	26
Sorafenib inhibits LPS-induced inflammation by regulating Lyn-MAPK-NF-kB/AP-1 pathway and TLR4 expression	25
Emerging roles of ferroptosis in cardiovascular diseases	25
Ferroptosis exacerbates hyperlipidemic acute pancreatitis by enhancing lipid peroxidation and modulating the immune microenvironment	25
Involvement of H2A variants in DNA damage response of zygotes	25
Lentinan suppresses the progression of neuroblastoma by inhibiting FOS-mediated transcription activation of VRK1 to stabilize p53 protein	25
Protective autophagy decreases lorlatinib cytotoxicity through Foxo3a-dependent inhibition of apoptosis in NSCLC	25
Stem cell-derived intestinal organoids: a novel modality for IBD	25
ALKBH5 promotes PD-L1-mediated immune escape through m6A modification of ZDHHC3 in glioma	25
USP32 deubiquitinase: cellular functions, regulatory mechanisms, and potential as a cancer therapy target	25
The pathological role of damaged organelles in renal tubular epithelial cells in the progression of acute kidney injury	25
The role of long non-coding RNA H19 in infertility	25
The endoplasmic reticulum pool of Bcl-xL prevents cell death through IP3R-dependent calcium release	24
NLRP3 inflammasome promoted the malignant progression of prostate cancer via the activation of caspase-1	24
MiR-148a deletion protects from bone loss in physiological and estrogen-deficient mice by targeting NRP1	24
Single-cell RNA transcriptome reveals the intra-tumoral heterogeneity and regulators underlying tumor progression in metastatic pancreatic ductal adenocarcinoma	24
Serpine1 mRNA confers mesenchymal characteristics to the cell and promotes CD8+ T cells exclusion from colon adenocarcinomas	24
Ablation of Cbl-b and c-Cbl in dendritic cells causes spontaneous liver cirrhosis via altering multiple properties of CD103+ cDC1s	24
IGF2BP3 enhances the mRNA stability of E2F3 by interacting with LINC00958 to promote endometrial carcinoma progression	24
MicroRNA in extracellular vesicles regulates inflammation through macrophages under hypoxia	24
Tumor-associated macrophages (TAMs) depend on MMP1 for their cancer-promoting role	24
Caspase 6/NR4A1/SOX9 signaling axis regulates hepatic inflammation and pyroptosis in ischemia-stressed fatty liver	24
Integrated analysis of high-throughput sequencing data reveals the key role of LINC00467 in the invasion and metastasis of testicular germ cell tumors	24
ICA69 aggravates ferroptosis causing septic cardiac dysfunction via STING trafficking	24
S100A2 induces epithelial–mesenchymal transition and metastasis in pancreatic cancer by coordinating transforming growth factor β signaling in SMAD4-dependent manner	23
Transcriptional and genetic alterations of cuproptosis-related genes correlated to malignancy and immune-infiltrate of esophageal carcinoma	23
KLHL14 is a tumor suppressor downregulated in undifferentiated thyroid cancer	23
Histone lactylation promotes malignant progression by facilitating USP39 expression to target PI3K/AKT/HIF-1α signal pathway in endometrial carcinoma	23
NEDD4L contributes to ferroptosis and cell growth inhibition in esophageal squamous cell carcinoma by facilitating xCT ubiquitination	23
Idebenone improves motor dysfunction, learning and memory by regulating mitophagy in MPTP-treated mice	23
Pathological roles of bone marrow adipocyte-derived monocyte chemotactic protein-1 in type 2 diabetic mice	23
Anlotinib enhances the antitumor immunity of radiotherapy by activating cGAS/STING in non-small cell lung cancer	23
N6-methyladenosine demethylase FTO suppressed prostate cancer progression by maintaining CLIC4 mRNA stability	23
Bithionol eliminates acute myeloid leukaemia stem-like cells by suppressing NF-κB signalling and inducing oxidative stress, leading to apoptosis and ferroptosis	23
Arginase: shedding light on the mechanisms and opportunities in cardiovascular diseases	23
Sophoridine derivative 6j inhibits liver cancer cell proliferation via ATF3 mediated ferroptosis	23
A VEGFR targeting peptide-drug conjugate (PDC) suppresses tumor angiogenesis in a TACE model for hepatocellular carcinoma therapy	23
NR1D1 deficiency in the tumor microenvironment promotes lung tumor development by activating the NLRP3 inflammasome	23
Repositioning linifanib as a potent anti-necroptosis agent for sepsis	22
TLR2/caspase-5/Panx1 pathway mediates necrosis-induced NLRP3 inflammasome activation in macrophages during acute kidney injury	22
MiR-92a/KLF4/p110δ regulates titanium particles-induced macrophages inflammation and osteolysis	22
The lncRNA MIAT regulates CPT-1a mediated cardiac hypertrophy through m6A RNA methylation reading protein Ythdf2	22
CHK1 inhibitor induced PARylation by targeting PARG causes excessive replication and metabolic stress and overcomes chemoresistance in ovarian cancer	22