OOIR: Observatory of International Research

Papers

(The TQCC of Acta Crystallographica Section D-Structural Biology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Are the St John's wort Hyp-1 superstructures different?	444
Comparison of two crystal polymorphs of NowGFP reveals a new conformational state trapped by crystal packing	220
EMhub: a web platform for data management and on-the-fly processing in scientific facilities	84
Structural visualization of transient interactions between the cis-acting acyltransferase and acyl carrier protein of the salinomycin modular polyketide synthase	59
Structure of the Fab fragment of a humanized 5E5 antibody to a cancer-specific Tn-MUC1 epitope	51
Using graphlet degree vectors to predict atomic displacement parameters in protein structures	51
Cryo2RT: a high-throughput method for room-temperature macromolecular crystallography from cryo-cooled crystals	49
Identifying and avoiding radiation damage in macromolecular crystallography	45
Data collection from crystals grown in microfluidic droplets	40
X-ray diffraction and in vivo studies reveal the quinary structure of Trypanosoma cruzi nucleoside diphosphate kinase 1: a novel helical oligomer structure	39
The crystal structure of CbpD clarifies substrate-specificity motifs in chitin-active lytic polysaccharide monooxygenases	37
Structural flexibility of Toscana virus nucleoprotein in the presence of a single-chain camelid antibody	35
A scalable strategy to solve structures of PDZ domains and their complexes	34
Updated restraint dictionaries for carbohydrates in the pyranose form	34
Crystal structure of DNA polymerase I from Thermus phage G20c	27
Structures of permuted halves of a modern ribose-binding protein	27
Exploring ligand dynamics in protein crystal structures with ensemble refinement	26
Structures of α-galactosaminidases from the CAZy GH114 family and homologs defining a new GH191 family of glycosidases	26
Structural characterization of the ACDC domain from ApiAP2 proteins, a potential molecular target against apicomplexan parasites	25
The crystal structure of the N-terminal domain of the backbone pilin LrpA reveals a new closure-and-twist motion for assembling dynamic pili in Ligilactobacillus ruminis	24
On bias, variance, overfitting, gold standard and consensus in single-particle analysis by cryo-electron microscopy	24
The three-dimensional structure of Drosophila melanogaster (6–4) photolyase at room temperature	22
A recurring packing contact in crystals of InlB pinpoints functional binding sites in the internalin domain and the B repeat	21
A radical approach to radicals	21
Overall protein structure quality assessment using hydrogen-bonding parameters	20

Analysis and validation of overall N-glycan conformation in Privateer	19
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent	18
Raw diffraction data are our ground truth from which all subsequent workflows develop	17
Training undergraduate research assistants with an outcome-oriented and skill-based mentoring strategy	15
Structural studies of β-glucosidase from the thermophilic bacterium Caldicellulosiruptor saccharolyticus	15
Medical contrast agents as promising tools for biomacromolecular SAXS experiments	15
Statistical analyses of the oxidized P-clusters in MoFe proteins using the bond-valence method: towards their electron transfer in nitrogenases	15
Pillar data-acquisition strategies for cryo-electron tomography of beam-sensitive biological samples	14
3D structures of the Plasmodium vivax subtilisin-like drug target SUB1 reveal conformational changes to accommodate a substrate-derived α-ketoamide inhibitor	14
On-grid and in-flow mixing for time-resolved cryo-EM	14
Time-resolved serial femtosecond crystallography on fatty-acid photodecarboxylase: lessons learned	14
Structural and functional analysis of the D-alanyl carrier protein ligase DltA from Staphylococcus aureus Mu50	14
Deciphering the crystal structure of a novel nanobody against the NEIL1 DNA glycosylase	14
Versatile microporous polymer-based supports for serial macromolecular crystallography	13
Frag4Lead: growing crystallographic fragment hits by catalog using fragment-guided template docking	13
Preparation and characterization of inactivated tick-borne encephalitis virus samples for single-particle imaging at the European XFEL	13
Molecular basis of transcriptional repression of anti-CRISPR by anti-CRISPR-associated 2	13
Alexei Vagin (1944–2023)	13
Michael James (1940–2023)	13
Crystal structures of the molecular class A β-lactamase TEM-171 and its complexes with tazobactam	13
Notes of a protein crystallographer: the advantages of combining new integrated methods of structure solution with traditional data visuals	13
The T₂ structure of polycrystalline cubic human insulin	13
Secret of Life: Rosalind Franklin, James Watson, Francis Crick, and the discovery of DNA's Double Helix. By Howard Markel. W. W. Norton & Co., 2021. Hardback, pp. 608. ISBN 978-1324002239.	12
Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket	12
Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization	12
Structural basis for SdgB- and SdgA-mediated glycosylation of staphylococcal adhesive proteins	12
Metalloprotein catalysis: structural and mechanistic insights into oxidoreductases from neutron protein crystallography	12
Structures of full-length VanR from Streptomyces coelicolor in both the inactive and activated states	12
eSPC: an online data-analysis platform for molecular biophysics	12
Biochemical and structural insights into an unusual, alkali-metal-independent S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803	12
Cryo-EM reveals binding of linoleic acid to SARS-CoV-2 spike glycoprotein, suggesting an antiviral treatment strategy	11
Structural mechanism of Escherichia coli cyanase	11
Thyroxine hormones visualized by the cryo-EM structure of bovine thyroglobulin	11
Submission of structural biology data for review purposes	11
Direct phasing algorithm for protein crystals with high solvent content using low-resolution diffraction data	11
Best practices for time-resolved serial synchrotron crystallography	11
Structural basis of the amidase ClbL central to the biosynthesis of the genotoxin colibactin	10
Crystal structure of the monocupin ring-cleaving dioxygenase 5-nitrosalicylate 1,2-dioxygenase fromBradyrhizobiumsp.	10
Raynals, an online tool for the analysis of dynamic light scattering	10
The LH–DH module of bacterial replicative helicases is the common binding site for DciA and other helicase loaders	10
The X-ray crystallography phase problem solved thanks to AlphaFold and RoseTTAFold models: a case-study report	10
A new inactive conformation of SARS-CoV-2 main protease	10
Elucidating polymorphs of crystal structures by intensity-based hierarchical clustering analysis of multiple diffraction data sets	10
Structural and functional characterization of a multi-domain GH92 α-1,2-mannosidase from Neobacillus novalis	10
Knowledge-based prediction of DNA hydration using hydrated dinucleotides as building blocks	10
Native glycosylation and binding of the antidepressant paroxetine in a low-resolution crystal structure of human myeloperoxidase	9
Determination of intracellular protein–ligand binding affinity by competition binding in-cell NMR	9
Dependence of crystallographic atomic displacement parameters on temperature (25–150 K) for complexes of horse liver alcohol dehydrogenase	9
Atomic resolution studies of S1 nuclease complexes reveal details of RNA interaction with the enzyme despite multiple lattice-translocation defects	9
Crystallographic fragment screening-based study of a novel FAD-dependent oxidoreductase from Chaetomium thermophilum. Corrigendum	9

Modelling covalent linkages in CCP4	9
Glycoside hydrolase subfamily GH5_57 features a highly redesigned catalytic interface to process complex hetero-β-mannans	8
Protonation states of hen egg-white lysozyme observed using D/H contrast neutron crystallography	8
Accelerating crystal structure determination with iterative AlphaFold prediction	8
New system for archiving integrative structures	8
Structural basis for substrate recognition in the Phytolacca americana glycosyltransferase PaGT3	8
Restoration of the 3D structure of insect flight muscle from a rotationally averaged 2D X-ray diffraction pattern	7
Correcting systematic errors in diffraction data with modern scaling algorithms	7
Crystal and solution structures of a novel antimicrobial peptide fromChrysomya megacephala	7
Crystal structure of the ferredoxin reductase component of carbazole 1,9a-dioxygenase from Janthinobacterium sp. J3	7
Buccaneer model building with neural network fragment selection	7
The impact of molecular variants, crystallization conditions and the space group on ligand–protein complexes: a case study on bacterial phosphotriesterase	7
Structural and biochemical characterization of the novel serpin Iripin-5 from Ixodes ricinus	7
Errors in structural biology are not the exception	7
Structural insights into choline-O-sulfatase reveal the molecular determinants for ligand binding	7
Expression and analysis of the SAM-dependent RNA methyltransferase Rsm22 from Saccharomyces cerevisiae	7
Protein–macrocycle polymorphism: crystal form IV of the Ralstonia solanacearum lectin–sulfonato-calix[8]arene complex	7
Structural and biophysical studies of new L-asparaginase variants: lessons from random mutagenesis of the prototypic Escherichia coli Ntn-amidohydrolase	7
XFEL structure of carbonic anhydrase II: a comparative study of XFEL, NMR, X-ray and neutron structures	7
Tomo Live: an on-the-fly reconstruction pipeline to judge data quality for cryo-electron tomography workflows	7
Atypical homodimerization revealed by the structure of the (S)-enantioselective haloalkane dehalogenase DmmarA from Mycobacterium marinum	7
VitroJet: new features and case studies	7
Structure and metal-binding properties of PA4063, a novel player in periplasmic zinc trafficking byPseudomonas aeruginosa	7
The High-Pressure Freezing Laboratory for Macromolecular Crystallography (HPMX), an ancillary tool for the macromolecular crystallography beamlines at the ESRF	7
Dynamics and Kinetics in Structural Biology: Unravelling Function Through Time-Resolved Structural Analysis. By Keith Moffat and Eaton E. Lattman. Wiley, New York, 2023, pp. 288. ISBN 978-1-119	7
Polyelectrolyte coating of cryo-EM grids improves lateral distribution and prevents aggregation of macromolecules	7
Structural and spectrophotometric investigation of two unnatural amino-acid altered chromophores in the superfolder green fluorescent protein	7
High-resolution structures of the bound effectors avadomide (CC-122) and iberdomide (CC-220) highlight advantages and limitations of the MsCI4 soaking system	6
Thermostable homologues of the periplasmic siderophore-binding protein CeuE from Geobacillus stearothermophilus and Parageobacillus thermoglucosidasius	6
Structural and functional analysis of the C-terminal region of Streptococcus gordonii SspB	6
AutoPX: a new software package to process X-ray diffraction data from biomacromolecular crystals	6
Structural features of chloroplast trigger factor determined at 2.6 Å resolution	6
Post-translational modifications in the Protein Data Bank	6
The missing link: covalent linkages in structural models	6
Increasing the bulk of the 1TEL–target linker and retaining the 10×His tag in a 1TEL–CMG2-vWa construct improves crystal order and diffraction limits	6
Structural analysis of wild-type and Val120Thr mutant Candida boidinii formate dehydrogenase by X-ray crystallography	6
Drosophila melanogaster frataxin: protein crystal and predicted solution structure with identification of the iron-binding regions	6
Atomic model validation using the CCP-EM software suite	6
Inhibition of Schistosoma mansoni carbonic anhydrase by the antiparasitic drug clorsulon: X-ray crystallographic and in vitro studies	6
Evaluating the impact of X-ray damage on conformational heterogeneity in room-temperature (277 K) and cryo-cooled protein crystals	6
The CCP4 suite: integrative software for macromolecular crystallography	6