OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Flow Chemistry is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Continuous flow process development for the synthesis of an industrial raw material via solvent-free aromatic Claisen rearrangement	24
Solid dosing in High-Throughput Experimentation: generalization of mass enhancer technologies for submilligram scale	21
FOMSy: 3D-printed flexible open-source microfluidic system and flow synthesis of PET-tracer	18
Multistep non-fouling continuous flow synthesis and PEG-functionalisation of biocompatible iron oxide nanoparticles for magnetic hyperthermia, photothermal heating and antifungal activity	17
Synthesis of new heterocyclic resveratrol analogues in milli- and microreactors: intensification of the Wittig reaction	15
Continuous flow Friedel–Crafts acetylation of phenols and electron-rich arenes and heteroarenes	14
Magnet-actuated microfluidic reactors with controllable Fe-based amorphous microspheres for tetracycline degradation	13
Determination of micromixing times in commercially available continuous-flow mixers: evaluation of the incorporation and interaction by exchange with the mean model	13
Seeded-growth synthesis of 20–60 nm monodisperse citrate-capped gold nanoparticles in a millifluidic reactor	13
Continuous synthesis of ε-caprolactone in a microreactor and kinetics insights into its side reactions	12
Correction: Seeded-growth synthesis of 20–60 nm monodisperse citrate-capped gold nanoparticles in a millifluidic reactor	11
Open-source multi-purpose sensor for measurements in continuous capillary flow	10
Kinetics and safeties of 2-Ethyl-1-hexanol nitration in a capillary-microreactor	9
Application of stop-flow micro-tubing reactor system in organic reaction development	9
Continuous flow synthesis of HMF from glucose using gadolinium (III) trifluoromethanesulfonate in Brønsted acidic ionic liquid as a catalytic system	9
Telescoped synthesis of vicinal diamines via ring-opening of electrochemically generated aziridines in flow	8
Expedited access to β-lactams via a telescoped three-component Staudinger reaction in flow	8
Correction to: The applications of organozinc reagents in continuous flow chemistry: Negishi coupling	7
Continuous one-pot synthesis of new spiro-fused indoles from biobased building blocks using carbamoylation and imidation reactions under ultrasonic irradiation	7
Continuous microflow synthesis of dimethyl-substituted cyclobutanetetracarboxylic dianhydrides and its application on polyimide films	7
Two deep learning methods in comparison to characterize droplet sizes in emulsification flow processes	7
Extraction and mass transfer of glyoxylic acid in a capillary microchannel	7
Meet The Flow Chemist – Alain George	7
Continuous preparation and reaction of nonaflyl azide (NfN3) for the synthesis of organic azides and 1,2,3-triazoles	6
Continuous flow organocatalyzed methoxycarbonylation of benzyl alcohol derivatives with dimethyl carbonate	6

Electrochemical telescoped synthesis of alkyl pinacol boranes	6
Microwave assisted flow synthesis of Ir-IrOx electrocatalysts for acidic oxygen evolution reaction: synthesis conditions and electrocatalytic performance correlation	6
Continuous flow synthesis of phenyl glucosazone and its conversion to 2H-1,2,3-Triazole building blocks	6
Safe and on-demand protocol for the continuous generation of SO2 and Cl2 for subsequent utilization in organic synthesis	6
A tri-fluid tortuous microfluidic chip for green synthesis of nanoparticles and inactivation of a model gram-negative bacteria: Intracellular components evaluation	6
Continuous dehydration of glycerol to Acrolein based on HPW/TS-COOH catalyzation	6
Asymmetric electrochemical synthesis in flow	6
Straightforward, scalable, solution-phase synthesis of peptide bonds in flow	5
Electrophilic cyclization of reticuline-type alkaloids in flow via o-quinol intermediates	5
Effects of two-phase periodic velocity on droplet coalescence inside microchannels	5
Selective synthesis of phenylhydroxylamine under slug flow conditions using Bayesian optimization	5
Continuous synthesis of benzaldehyde by ozonolysis of styrene in a micro-packed bed reactor	5
Generation of styrene droplets in a coaxial flow device	5
Accurate determination of the kinetics of toluene nitration in a liquid–liquid microflow system	5
Design and implementation of an automated DT-PhotoFluor radiosynthesis module for 18F-fluorination of aliphatic, branched chain amino acids	5
5-Hydroxymethylfurfural synthesis from fructose over deep eutectic solvents in batch reactors and continuous flow microreactors	5
Practical synthesis of tetrahydrofolate by highly efficient catalytic hydrogenation in continuous flow	4
Functionalization of unsaturated carbon–carbon bonds by continuous-flow ozonolysis	4
Selective monosubstitution on a trichlorosilane with highly reactive organolithium compounds in a microflow reactor	4
Comparative economic analysis of batch vs. continuous manufacturing in catalytic heterogeneous processes: impact of catalyst activity maintenance and materials costs on total costs of manufacturing in	4
Efficient “One-Column” grignard generation and reaction in continuous flow	4
Driving sustainability through adoption of hybrid manufacturing in small molecule API production	4
Correction to: Continuous diameter increase reactor – a reactor concept for maximizing productivity by a controlled diameter extension	4
Rapid prototyping of a modular optical flow cell for image-based droplet size measurements in emulsification processes	4
Correction to: Voltage-driven microfluidic synthesis of magnetite and gold nanomaterials	4
Emerging Investigators in Flow Chemistry 2023	4
Process design of two-step mononitration of m-xylene in a microreactor	4
Rapid plugged flow synthesis of nucleoside analogues via Suzuki-Miyaura coupling and heck Alkenylation of 5-Iodo-2’-deoxyuridine (or cytidine)	4
Development of an automated flow chemistry affinity-based purification process for DNA-encoded chemistry	4
Continuous-flow synthesis of prenyl chloride on-demand through surface-mediated hydrochlorination	4
Towards an approach to small-scale aryllithium flash flow chemistry using low-cost, low volume reactors	4
Continuous stirred-tank degradation of persistent dyes via recycled iron/periodate oxidation system: process optimization	3
High-temperature S–S, S–O, and S–C bond transfer hydrogenolysis by lower alcohols in continuous flow mode	3
A fully continuous-flow process for the synthesis of 4-nitropyrazole	3
Correction to: Synthesis of 2,3,5-trimethylbenzoquinone from 2,3,6-trimethylphenol and tert-butyl hydroperoxide in microreactors	3
Mediated formic acid flow fuel cell (MFAFFC) based on biomimetic electrolytes	3
Facile microfluidic device for droplets emulsion from small samples	3
Continuous flow ozonolysis of cardanol for greener synthesis of bio-based monomers	3
Best practice approach for temperature measurement in flow chemistry based on CFD simulation	3
Synthesis of BuNENA in a continuous flow microreactor	3
Investigation into a high-p,T,c continuous flow synthesis of myristyl-γ-picolinium chloride (MGPC) – a preservative in pharmaceutical formulations	3
Process intensification toward galanthamine: continuous flow N-methylation of demethylbromonarwedine	3
Formation of double emulsion droplets in flow-focusing microchips: a numerical parametric study	3
Investigations on the continuous flow generation of 2,6-dichloro-N-fluoropyridinium tetrafluoroborate using F2 gas	2
An eco-friendly and very low catalyst loading continuous condensation of primary amines and 1,3 Di carbonyl compounds: Synthesis of enaminones and enaminoesters by microreactor technology	2
Efficient pinnick oxidation by a superheated micro-reaction process	2
HO-SAS catalyzed protection and deprotection of aldehydes and alcohols in continuous flow reactors	2
Continuous Flow Generation of Highly Reactive Organometallic Intermediates: A Recent Update	2
Editorial	2
Development of continuous flow photochemistry-based protocol for the synthesis of Sulindac related impurity	2

Dominance of heat transfer limitations in conventional sol-gel synthesis of LTA revealed by microcrystallization	2
Meet the Flow Chemist – Dr. Anna G. Slater	2
Multivariate curve resolution for kinetic modeling and scale-up prediction	2
Flow platform for the synthesis of benzodiazepines	2
Enzymatic kinetic resolution in flow for chiral mandelic acids	2
Nitration process of 2-(2,4-dichlorophenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one in a microreactor	2
Continuous flow synthesis of (E)-O-(3-chloro-2-propenyl)hydroxylamine: a key intermediate of clethodim	2
Continuous flow synthesis of meso-substituted porphyrins with inline UV–Vis analysis	2
Micro-Batch flow reactor for the photoproduction of H2O2 from water/real seawater	2