OOIR: Observatory of International Research

Papers

(The H4-Index of Cells is 98. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Nuclear–Cytoplasmic Shuttling of the Usher Syndrome 1G Protein SANS Differs from Its Paralog ANKS4B	723
Timing of Blood Sample Processing Affects the Transcriptomic and Epigenomic Profiles in CD4+ T-cells of Atopic Subjects	662
Diallyl Trisulfide Causes Male Infertility with Oligoasthenoteratospermia in Sitotroga cerealella through the Ubiquitin–Proteasome Pathway	491
MiR-22 Deficiency Fosters Hepatocellular Carcinoma Development in Fatty Liver	462
Dysregulation of Metabolism and Proteostasis in Skeletal Muscle of a Presymptomatic Pompe Mouse Model	441
Integration of Transcriptome and MicroRNA Profile Analysis of iMSCs Defines Their Rejuvenated State and Conveys Them into a Novel Resource for Cell Therapy in Osteoarthritis	416
Distinct Traits of Structural and Regulatory Evolutional Conservation of Human Genes with Specific Focus on Major Cancer Molecular Pathways	402
α7 Nicotinic Acetylcholine Receptors May Improve Schwann Cell Regenerating Potential via Metabotropic Signaling Pathways	335
Spectral Profiling of Early αsyn Aggregation in HEK293 Cells Modified to Stably Express Human WT and A53T-αsyn	329
Regulation of Hindbrain Vascular Development by rps20 in Zebrafish	319
Inter-Relationship Between Melanoma Vemurafenib Tolerance Thresholds and Metabolic Pathway Choice	304
Modulation of Neurexins Alternative Splicing by Cannabinoid Receptors 1 (CB1) Signaling	301
Insulin in Myenteric Neurons: Time-Dependent and Regional Changes in Type 1 Diabetic Rats	294
Circular RNA ZNF277 Sponges miR-378d to Inhibit the Intracellular Survival of Mycobacterium tuberculosis by Upregulating Rab10	289
Rotavirus Spreads in a Spatially Controlled Manner	280
Development of Antibody–Drug Conjugates for Malignancies of the Uterine Corpus: A Review	264
Reversible Modulation of Motile Cilia by a Benzo[e][1,2,4]triazinone: A Potential Non-Hormonal Approach to Male Contraception	258
Dauricine Impedes the Tumorigenesis of Lung Adenocarcinoma by Regulating Nrf2 and Reactive Oxygen Species	248
Targeting the Cargo Receptor TMED9 as a Therapeutic Strategy Against Brain Tumors	243
Kynurenic Acid Synthesis from D-Kynurenine in the Cerebellum: A Distinct Role of D-Amino Acid Oxidase	235
A Synthetic Sponge System Against miRNAs of the miR-17/92 Cluster Targets Transcriptional MYC Dosage Compensation in Aneuploid Cancer	231
Orlistat Confers Neuroprotection in Traumatic Brain Injury by Modulating Microglial Lipid Metabolism	216
Localization and Dynamics of the Cell Shape-Determining Csd2 Protein Complex in H. pylori	206
Alpha-Keratin, Keratin-Associated Proteins and Transglutaminase 1 Are Present in the Ortho- and Parakeratinized Epithelium of the Avian Tongue	204
Innate–Acquired Linkage in Immunotherapy	200

Targeting Hdm2 and Hdm4 in Anticancer Drug Discovery: Implications for Checkpoint Inhibitor Immunotherapy	195
Nuclear Transporter IPO13 Is Central to Efficient Neuronal Differentiation	185
Polycystin-2 Mediated Calcium Signalling in the Dictyostelium Model for Autosomal Dominant Polycystic Kidney Disease	185
Involvement of Substance P (SP) and Its Related NK1 Receptor in Primary Sjögren’s Syndrome (pSS) Pathogenesis	184
Vascular Endothelial Growth Factor B Modulates Cardiac Functions via Ferroptosis Pathways in Post-Myocardial Infarction	175
Redefining Precision Management of r/r Large B-Cell Lymphoma: Novel Antibodies Take on CART and BMT in the Quest for Future Treatment Strategies	170
Early Dietary Exposures Epigenetically Program Mammary Cancer Susceptibility through Igf1-Mediated Expansion of the Mammary Stem Cell Compartment	166
High-Dimensional Cytometry Dissects Immunological Fingerprints of Idiopathic Inflammatory Myopathies	164
Pre-Conception Maternal Obesity Confers Autism Spectrum Disorder-like Behaviors in Mice Offspring Through Neuroepigenetic Dysregulation	163
Blockade of Sialylation with Decrease in Polysialic Acid Levels Counteracts Transforming Growth Factor β1-Induced Skin Fibroblast-to-Myofibroblast Transition	163
First Edition Special Issue on “Cellular and Molecular Mechanisms in Immune Regulation”	163
The Interface of Tumour-Associated Macrophages with Dying Cancer Cells in Immuno-Oncology	162
Hypoxia-Induced Fibroblast IL-6 Promotes Immunosuppressive Macrophage Phenotypes in Pancreatic Cancer	160
Intervertebral Disc Degeneration and Regeneration: New Molecular Mechanisms and Therapeutics	159
Enhancing Dental Pulp Stem Cell Proliferation and Odontogenic Differentiation with Protein Phosphatase 1-Disrupting Peptide: An In Vitro Study	159
High BECN1 Expression Negatively Correlates with BCL2 Expression and Predicts Better Prognosis in Diffuse Large B-Cell Lymphoma: Role of Autophagy	158
Curcumin-Mediated Resistance to Lenvatinib via EGFR Signaling Pathway in Hepatocellular Carcinoma	155
Celastrol-Loaded Hyaluronic Acid/Cancer Cell Membrane Lipid Nanoparticles for Targeted Hepatocellular Carcinoma Prevention	155
Maternal and Intrauterine Influences on Feto-Placental Growth Are Accompanied by Sexually Dimorphic Changes in Placental Mitochondrial Respiration, and Metabolic Signalling Pathways	154
Characterizing Relevant MicroRNA Editing Sites in Parkinson’s Disease	149
Regulation of Cellular Ribonucleoprotein Granules: From Assembly to Degradation via Post-translational Modification	147
Chronic AMPK Activation Reduces the Expression and Alters Distribution of Synaptic Proteins in Neuronal SH-SY5Y Cells	146
Promising and Minimally Invasive Biomarkers: Targeting Melanoma	144
SCD5 Regulation by VHL Affects Cell Proliferation and Lipid Homeostasis in ccRCC	144
Microglia Mitigate Neuronal Activation in a Zebrafish Model of Dravet Syndrome	141
Hedgehog Signaling in CNS Remyelination	140
Presynaptic 5-HT2A-mGlu2/3 Receptor–Receptor Crosstalk in the Prefrontal Cortex: Metamodulation of Glutamate Exocytosis	139
6-Shogaol Exhibits a Promoting Effect with Tax via Binding HSP60 in Non-Small-Cell Lung Cancer	139
Mitochondria Transfer in Brain Injury and Disease	139
Loss of Flocculus Purkinje Cell Firing Precision Leads to Impaired Gaze Stabilization in a Mouse Model of Spinocerebellar Ataxia Type 6 (SCA6)	138
Effects of the Phosphodiesterase 10A Inhibitor MR1916 on Alcohol Self-Administration and Striatal Gene Expression in Post-Chronic Intermittent Ethanol-Exposed Rats	137
New JAK3-INSL3 Fusion Transcript—An Oncogenic Event in Cutaneous T-Cell Lymphoma	135
The Role of FBXW7 in Gynecologic Malignancies	133
B7-H3 in Cancer Immunotherapy—Prospects and Challenges: A Review of the Literature	133
Enhancement of Tendon Repair Using Tendon-Derived Stem Cells in Small Intestinal Submucosa via M2 Macrophage Polarization	129
Calpains at the Crossroads of Spinal Cord Physiology, Plasticity, and Pathology	129
Current Status of α-Synuclein Biomarkers and the Need for α-Synuclein PET Tracers	129
Radiation-Induced Fibrosis (RIF) in Head and Neck Squamous Cell Carcinoma (HNSCC): A Review	128
Prognostic Role of Circulating Tumor Cell Trajectories in Metastatic Colorectal Cancer	128
β2-Adrenoceptor Activation Favor Acquisition of Tumorigenic Properties in Non-Tumorigenic MCF-10A Breast Epithelial Cells	128
A Comparative Analysis of Mucus Immunomodulatory Properties from Seven Marine Gastropods from the Mediterranean Sea	126
Characterization of the Aquaporin-9 Inhibitor RG100204 In Vitro and in db/db Mice	125
PTPRK, an EGFR Phosphatase, Is Decreased in CeD Biopsies and Intestinal Organoids	123
Validation of Clinical-Grade Electroporation Systems for CRISPR-Cas9-Mediated Gene Therapy in Primary Hepatocytes for the Correction of Inherited Metabolic Liver Disease	123
Histopathological and Ultrastructural Study of a Canine Langerhans Cell Tumour (Canine Cutaneous Histiocytoma)	121
Cistanoside F Ameliorates Lipid Accumulation and Enhances Myogenic Differentiation via AMPK-Dependent Signaling in C2C12 Myotubes	117
Exploring Risk and Protective Factors in Parkinson’s Disease	117
Mycobacterium tuberculosis FadD18 Promotes Proinflammatory Cytokine Secretion to Inhibit the Intracellular Survival of Bacillus Calmette–Guérin	117
Treg Cell Therapeutic Strategies for Breast Cancer: Holistic to Local Aspects	116
Neoadjuvant Radiochemotherapy Alters the Immune and Metabolic Microenvironment in Oral Cancer—Analyses of CD68, CD163, TGF-β1, GLUT-1 and HIF-1α Expressions	115

Neuroretinal Cell Culture Model as a Tool for the Development of New Therapeutic Approaches for Oxidative Stress-Induced Ocular Diseases, with a Focus on Glaucoma	115
The EXTREME Regimen Associating Cetuximab and Cisplatin Favors Head and Neck Cancer Cell Death and Immunogenicity with the Induction of an Anti-Cancer Immune Response	115
Heat Shock Proteins in Pancreatic Cancer: Pathogenic Mechanisms and Clinical Implications	112
Therapeutic Potential of Emricasan, a Pan-Caspase Inhibitor, in Reducing Cell Death and Extracellular Matrix Accumulation in Fuchs Endothelial Corneal Dystrophy	111
Culture and Immunomodulation of Equine Muscle-Derived Mesenchymal Stromal Cells: A Comparative Study of Innovative 2D versus 3D Models Using Equine Platelet Lysate	110
Activation of the Rat P2X7 Receptor by Functionally Different ATP Activation Sites	110
Correction: Winkler et al. The Adhesion G-Protein-Coupled Receptor GPR115/ADGRF4 Regulates Epidermal Differentiation and Associates with Cytoskeletal KRT1. Cells 2022, 11, 3151	109
Correction: Li et al. Nodal Facilitates Differentiation of Fibroblasts to Cancer-Associated Fibroblasts that Support Tumor Growth in Melanoma and Colorectal Cancer. Cells 2019, 8, 538	108
Haplotype Structures and Protein Levels of TGFB1 in HPV Infection and Cervical Lesion: A Case-Control Study	107
Centella asiatica-Derived Endothelial Paracrine Restores Epithelial Barrier Dysfunction in Radiation-Induced Enteritis	106
The Effect of the Donor’s and Recipient’s Sex on Red Blood Cells Evaluated Using Transfusion Simulations	106
Macrophage Inhibitor Clodronate Enhances Liver Transduction of Lentiviral but Not Adeno-Associated Viral Vectors or mRNA Lipid Nanoparticles in Neonatal and Juvenile Mice	105
Brain Natriuretic Peptide Protects Cardiomyocytes from Apoptosis and Stimulates Their Cell Cycle Re-Entry in Mouse Infarcted Hearts	105
Computational Imaging: The Next Revolution for Biophotonics and Biomedicine	103
Characteristics of Human Nasal Turbinate Stem Cells under Hypoxic Conditions	103
Botulinum Toxin Treatment of Adult Muscle Stem Cells from Children with Cerebral Palsy and hiPSC-Derived Neuromuscular Junctions	103
HypoxaMIRs: Key Regulators of Hallmarks of Colorectal Cancer	102
Recent Technologies on 2D and 3D Imaging Flow Cytometry	102
Control of Replication Stress Response by Cytosolic Fe-S Cluster Assembly (CIA) Machinery	100
Automated Pupillometry as an Assessment Tool for Intracranial Hemodynamics in Septic Patients	100
Region-Specific Homeostatic Identity of Astrocytes Is Essential for Defining Their Response to Pathological Insults	99
The Role of RAC2 and PTTG1 in Cancer Biology	99
Migration of Myogenic Cells Is Highly Influenced by Cytoskeletal Septin7	98
SERPIN-Derived Small Peptide (SP16) as a Potential Therapeutic Agent against HIV-Induced Inflammatory Molecules and Viral Replication in Cells of the Central Nervous System	98
Brain Vascular Health in ALS Is Mediated through Motor Cortex Microvascular Integrity	98