OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Advanced Research is 67. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Rural-urban disparities in cardiovascular and other competing risk of death among cancer patients	314
Derivation of “Egyptian varices prediction (EVP) index”: A novel noninvasive index for diagnosing esophageal varices in HCV Patients	305
Value of ascitic fluid lipids in the differentiation between cirrhotic and malignant ascites	298
The therapeutic value of “Bile Transfer” for complications of acute pancreatitis: A retrospective clinical study	279
Rab32-based vesicles coordinate mitochondria and actin for spindle migration and organelle rearrangement in oocyte meiosis	234
Transglutaminase 2 modulates inflammatory angiogenesis via vascular endothelial growth factor receptor 2 pathway in inflammatory bowel disease	231
Modulation of Macrophage ferroptosis under the guide of infrared thermography promotes the healing of pressure injuries	223
Lipidomics identified novel cholesterol-independent predictors for risk of incident coronary heart disease: Mediation of risk from diabetes and aggravation of risk by ambient air pollution	204
Advancements in bone organoids: perspectives on construction methodologies and application strategies	202
Pomegranate peel extract alleviates diabetic retinopathy by suppressing the PI3K/AKT/HIF-1α/VEGF pathway and gut microbiota modulation	201
Not only the top: Type I topoisomerases function in multiple tissues and organs development in plants	198
Transcriptomic and metabolomic profiles reveal the functions of IGF-1 c.258 A > G synonymous mutation in milk fat content	175
Lactobacillus johnsonii-derived extracellular vesicles carrying GAPDH protect against ulcerative colitis through modulating macrophage polarization	168
OsCPK9-mediated Thr105 phosphorylation activates OsCATC to enhance drought tolerance in rice	161
A multi-omics approach reveals that lotus root polysaccharide iron ameliorates iron deficiency-induced testicular damage by activating PPARγ to promote steroid hormone synthesis	160
Association between dietary amino acid intake and the risk of metabolic dysfunction-associated steatotic liver disease	159
Unraveling the nexus in the neuro-neoplastic progression of colorectal cancer: Potential role of β2-adrenergic receptor (β2-AR)	152
RNA methylation modifications in neurodegenerative diseases: Focus on their enzyme system	137
Unraveling competitive protein interactions: A critical step toward improved production and therapeutics	135
SCAP deficiency facilitates obesity and insulin resistance through shifting adipose tissue macrophage polarization	135
Functions of FGF21 and its role in cardiac hypertrophy	125
Clostridium butyricum and its metabolites regulate macrophage polarization through miR-146a to antagonize gouty arthritis	119
CHMP4C promotes pancreatic cancer progression by inhibiting necroptosis via the RIPK1/RIPK3/MLKL pathway	118
Gossypium purpurascens genome provides insight into the origin and domestication of upland cotton	114
Optimizing therapeutic efficacy of antifungal peptides via strategic terminal amino acid modification	112

Population genomics analyses reveal the role of hybridization in the rapid invasion of fall armyworm	111
Defect passivation and transformation of Ti3C2Tx MXene hollow microsphere for superior electrochemical performance and sodium-ions storage	110
Autoimmune responses to myelin-associated proteins as diagnostic and prognostic biomarkers of relapsing-remitting multiple sclerosis: Associations with human herpesvirus-6 and Epstein-Barr virus react	106
A sustainable molybdenum oxysulphide-cobalt phosphate photocatalyst for effectual solar-driven water splitting	105
Applications of single-cell analysis in immunotherapy for lung cancer: Current progress, new challenges and expectations	103
Development and clinical validation of a novel protein biomarkers-based algorithm for risk prediction and diagnosis of advanced liver fibrosis: a multi-centre study	101
Trichosanthin elicits antitumor activity via MICU3 mediated mitochondria calcium influx	100
Insights into modifiable risk factors of erectile dysfunction, a wide-angled Mendelian Randomization study	99
Ginsenoside Rh4 inhibits colorectal cancer via the modulation of gut microbiota-mediated bile acid metabolism	99
Clinical evaluation of cell-free and cellular metagenomic next-generation sequencing of infected body fluids	98
The transcription factor PbbHLH164 is destabilized by PbRAD23C/D.1 and mediates ethylene biosynthesis during pear fruit ripening	98
Four distinct pathways involved in a “tug-of-war” lead to the non-linear nature of phenolic chemistry during lactic acid fermentation of fruits and vegetables	94
Digital techniques and trends for seed phenotyping using optical sensors	92
c-Myc-PANK3-EMT axis regulates the structure and function of intestinal barrier in ulcerative colitis	91
Redox status of the plant cell determines epigenetic modifications under abiotic stress conditions and during developmental processes	91
Kaempferol alleviates myocardial ischemia injury by reducing oxidative stress via the HDAC3-mediated Nrf2 signaling pathway	91
Synergistic effect of cold gas plasma and experimental drug exposure exhibits skin cancer toxicity in vitro and in vivo	90
Molecular mechanisms of amyloid disaggregation	90
TRPM2-mediated feed-forward loop promotes chondrocyte damage in osteoarthritis via calcium-cGAS-STING-NF-κB pathway	89
NRIR promotes immune escape in hepatocellular cancer by regulating IFNγ-induced PD-L1 expression	85
The NLRP3 molecule influences the therapeutic effects of mesenchymal stem cells through Glut1-mediated energy metabolic reprogramming	85
Adaptive bilirubin nanoscavenger alleviates pulmonary oxidative stress and inflammation for acute lung injury therapy	84
A micropillar array-based microfluidic chip for label-free separation of circulating tumor cells: The best micropillar geometry?	83
Genomic loci associated with leaf abscission contribute to machine picking and environmental adaptability in upland cotton (Gossypium hirsutum L.)	82
DNA hypomethylation-mediated upregulation of GADD45B facilitates airway inflammation and epithelial cell senescence in COPD	82
High value-added application of a renewable bioresource as acaricide: Investigation the mechanism of action of scoparone against Tetranychus cinnabarinus	82
Forsythiaside A alleviates acute lung injury by inhibiting inflammation and epithelial barrier damages in lung and colon through PPAR-γ/RXR-α complex	82
Spatial-temporal lipidomics reveals dysregulated lipid metabolism in mouse brain during Alzheimer’s disease progression	82
Hierarchical double-layer microneedles accomplish multicenter skin regeneration in diabetic full-thickness wounds	80
Lactation duration and the risk of type 2 diabetes mellitus in parous women: A perspective on socioeconomic status disparity	80
Noninvasive detection and differentiation of gastric malignancy using cell-free DNA biomarkers	80
Metabolic interactions drive microbial community succession and functional expression of Nongxiangxing (Strong-flavor) daqu	78
CDK4/6 inhibitor PD-0332991 suppresses hepatocarcinogenesis by inducing senescence of hepatic tumor-initiating cells	76
The advent of precision nutrigeroscience in cancer: from clinic towards molecular biology	76
Extracellular matrix-inspired multi-morphology microspheres harness osteogenic-prone stem cells to recruit and reprogram adjacent stem cells for synergistic bone regeneration	71
Strain specificity of lactobacilli with promoted colonization by galactooligosaccharides administration in protecting intestinal barriers during Salmonella infection	70
NCAPD3 promotes diffuse large B-cell lymphoma progression through modulating SIRT1 expression in an H3K9 monomethylation-dependent manner	69
Intracellular Fusobacterium nucleatum infection increases METTL3-mediated m6A methylation to promote the metastasis of esophageal squamous cell carcinoma	69
Full dimensional dynamic 3D convolution and point cloud in pulmonary nodule detection	69
CD34+CLDN5+ tumor associated senescent endothelial cells through IGF2-IGF2R signaling increased cholangiocellular phenotype in hepatocellular carcinoma	68
Rationally designed BCR-ABL kinase inhibitors for improved leukemia treatment via covalent and pro-/dual-drug targeting strategies	67
The BET inhibitor JQ1 targets fat metabolism and counteracts obesity	67
Transcription factor Meis1 act as a new regulator of ischemic arrhythmias in mice	67