OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Neurogastroenterology and Motility is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Association Between the Cool Temperature-dependent Suppression of Colonic Peristalsis and Transient Receptor Potential Melastatin 8 Activation in Both a Randomized Clinical Trial and an Animal Model	61
The Use of Intraoperative Esophageal Functional Luminal Imaging Probe for Prediction of Therapeutic Outcomes in Achalasia Patients	53
Expanding the Physiological Role of the Endoluminal Functional Lumen Imaging Probe From the Esophagus to Pediatric Pylorus	43
Achalasia: The Current Clinical Dilemma and Possible Pathogenesis	42
Breaking Barriers in Functional Dyspepsia: A Systematic Review and Meta-analysis on Duodenal Tight Junction Protein Expression	38
Hypercontractile Esophagus: Clinical and Manometric Features From a Multicenter Korean Cohort	36
Real-world Application of the Chicago Classification Version 4.0 for Esophageal Manometry: Asian Multicenter Study	36
Disorders of Gut–Brain Interaction and Psychological Comorbidity in Singapore: Insights From the Rome IV Global Epidemiology Study	33
Spot Hydrogen Breath Test: A Great Hockey Player Plays Where the Puck Is Going to Be	28
Effect of Anti-reflux Mucosal Ablation on Esophageal Motility in Patients With Gastroesophageal Reflux Disease: A Study Based on High-resolution Impedance Manometry	28
Ambulatory Impedance-pH Assessment Is the Industry Standard But Is It Always the Best Choice?	26
Clinical Trial: Efficacy of Mosapride Controlled-release and Nortriptyline in Patients With Functional Dyspepsia: A Multicenter, Double-placebo, Double-blinded, Randomized Controlled, Parallel Clinica	25
The Effects of Fermented Rice Drink With Lactiplantibacillus plantarum JSA22 in Overweight Irritable Bowel Syndrome Patients: A Randomized, Double-blind, Placebo-controlled Study	25
Clinical Outcomes of Endoscopic Radiofrequency Stretta Therapy for Gastroesophageal Reflux Disease Treatment: A Retrospective Analysis From 2 Tertiary Centers in Korea	25
Pyloric Functional Lumen Imaging Probe Measurements Are Dependent on Balloon Position	22
Revisiting the Role of Esophageal Mucosal Dilated Intercellular Spaces in the Diagnosis and Pathophysiology of Heartburn	22
Refractory Gastroesophageal Reflux Disease: Diagnosis and Management	22
Irritable Bowel Syndrome-like Symptoms in Patients With Ulcerative Colitis in Remission as Compared to Irritable Bowel Syndrome: Symptom Severity and Inflammatory Markers	22
Validation of the London Classification for Rectal Hyposensitivity in an Anorectal Manometry Database of 2540 Patients With Functional Defecatory Disorder	21
Efficacy of Quadruple-coated Probiotics in Patients With Irritable Bowel Syndrome: A Randomized, Double-blind, Placebo-controlled, Parallel-group Study	21
Distinct Effects of Non-absorbed Agents Rifaximin and Berberine on the Microbiota-Gut-Brain Axis in Dysbiosis-induced Visceral Hypersensitivity in Rats	21
Infantile Colic and the Subsequent Development of the Irritable Bowel Syndrome	17
Impact of Enhanced Dietary Education Program on Gastrointestinal Symptoms in Patients With Functional Gastrointestinal Disorders: A Multicenter Prospective Pilot Study	17
Autonomic Dysfunction and Somatization in Young Patients With Irritable Bowel Syndrome and Mitral Valve Prolapse Syndrome	15
From Belief to Behavior: Closing the Knowledge–Practice Gap in Irritable Bowel Syndrome Self-management	15

Erratum	15
Exploring Diagnostic Challenges at the Intersection of Eating Disorders and Functional Dyspepsia: Implications for Rome V	15
Patients' Knowledge, Attitudes, and Practices Regarding Non-pharmacological Treatments for Irritable Bowel Syndrome	14
Influence of Menthol Infusion on Esophageal Peristalsis in Patients With Ineffective Esophageal Motility	14
Clinical Implications of the Gastroesophageal Reflux Disease Questionnaire and Reflux Symptom Index in Patients With Suspected Laryngopharyngeal Reflux Symptoms	13
Heart Rate Variability and Somatization in Adolescents With Irritable Bowel Syndrome	13
Exploring the Atypical Allergy Spectrum in Disorders of Gut-Brain Interactions: From Food to Aeroallergens	12
Gastric Myoelectrical Activity Subtypes in Functional Dyspepsia and Gastroparesis	12
Confocal Laser Endomicroscopy With Duodenal Food Challenge Does Not Predict Triggering Food Items in Eosinophilic Esophagitis: Results From a Pilot Trial	12
Implementing a Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols Diet in Asia: Addressing Cultural, Clinical and Practical Challenges	12
Randomized Multicenter Study to Evaluate the Efficacy and Safety of Fexuprazan According to the Timing of Dosing in Patients With Erosive Esophagitis	12
Estimating Probability for Esophageal Obstruction: A Diagnostic Decision Support Tool Applying Machine Learning to Functional Lumen Imaging Probe Panometry	12
Multiple Sclerosis Is Associated With Achalasia and Diffuse Esophageal Spasm	12
Phrenic Ampulla Emptying Dysfunction in Patients with Esophageal Symptoms	11
Physical Activity as a Therapeutic Strategy for Functional Dyspepsia	11
Assessing Treatment Outcomes in Achalasia Using 4-Dimensional High-resolution Impedance Manometry	11
The Value of 3-Dimensional Anorectal Manometry in the Evaluation of Obstetric Anal Sphincter Injuries	11
Diagnostic Criteria and Symptom Profiles in Adult Idiopathic Gastroparesis: A Systematic Review	10
Multiple Rapid Swallows: What Is the Optimal Protocol for Evaluation of Esophageal Contraction Reserve?	10
Small Intestinal Bacterial Overgrowth Complicating Gastrointestinal Manifestations of Systemic Sclerosis: A Systematic Review and Meta-analysis	10
Differences in Prevalence and Psychosocial Characteristics of Irritable Bowel Syndrome According to Rome III and Rome IV Criteria in Medical and Nursing Students	10
Bile Acid and Gut Microbiota in Irritable Bowel Syndrome	10
Effect of Buspirone on Upper Gastrointestinal Disorders of Gut–Brain Interaction: A Systematic Review and Meta-analysis	9
Belching and Reflux: The Relationship and the Underlying Mechanism	9
Pylorus Endoluminal Functional Luminal Imaging Probe Measurements in Children Are Determined by Age and Are Distinctly Different From Adult Values	9
Predicting Responsiveness to Biofeedback Therapy Using High-resolution Anorectal Manometry With Integrated Pressurized Volume	9
The Stressed Gut: Region-specific Immune and Neuroplasticity Changes in Response to Chronic Psychosocial Stress	9
Factors Associated With the Prevalence of Irritable Bowel Syndrome: The Miyagi Part of the Tohoku Medical Megabank Project Community-based Cohort Study	9
Substrate-dependent Differences of Colonic Hydrogen Production in a Patient With Fructose Malabsorption	8
Constipation in Patients With Chronic Kidney Disease	8
A Higher Manometric Esophageal Length to Height Ratio in Achalasia Explains the Lower Prevalence of Hiatal Hernia	8
Comparison of Fexuprazan and Esomeprazole for the Control of Nocturnal Gastroesophageal Reflux Symptoms: A Randomized, Crossover Study	8
The Implications of Mucosal Integrity and Microinflammation in the Pathogenesis of Gastroesophageal Reflux Disease	8
Effectiveness of Abdominal Massage Versus Kinesio Taping in Women With Chronic Constipation: A Randomized Controlled Trial	7
Baseline Impedance via Manometry Predicts Pathological Mean Nocturnal Baseline Impedance in Isolated Laryngopharyngeal Reflux Symptoms	7
Multimorbidity of Allergic Diseases Is Associated With Functional Gastrointestinal Disorders in a Young Japanese Population	7
Disorders of Gut-Brain Interaction in Children With Down Syndrome	7
Association Between Psychological Burden and Unexplained High Upper Esophageal Sphincter Basal Pressure	7
An Optogenetics-based Approach to Regulate Colonic Contractions by Modulating the Activity of the Interstitial Cells of Cajal in Mice	7
Mean Nocturnal Baseline Impedance and Post-reflux Swallow-induced Peristaltic Wave Index Could Identify Gastroesophageal Reflux Disease but pH-Impedance Metrics Alone Might Not Correlate With Proton P	7
2022 Seoul Consensus on Clinical Practice Guidelines for Functional Constipation	7
From Morphology to Motion: Cine-magnetic Resonance Imaging in the Functional Assessment of Pseudo-obstruction	7
The Esophageal Response to Distension on Functional Lumen Imaging Probe Panometry Is Minimally Changed by Conscious Sedation in Healthy Asymptomatic Subjects	7
Editing Multichannel Intraluminal Impedance-pH Tracings to Reduce Non-reflux-related Esophageal Acidification	7
Roles of Cytokines in Pathological and Physiological Gastroesophageal Reflux Exposure	7
Diet, Physical Activity, and Chronic Constipation: Unveiling the Combined Effects for Better Treatment Strategies	6
Globus: Its True Relationship to Acid Reflux? Opposing Patterns of Location-specific Basal Pressure Compared to Gastroesophageal Reflux Disease	6
Length of the Barrett’s Esophagus Is Proportional to the Abnormality of Esophageal Motility and Anti-reflux Barrier	6
The Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols Diet Is Effective in Irritable Bowel Syndrome With Constipation: A Single Center Tertiary Care Clinical Practice Evaluatio	6
Preoperative Esophageal Physiologic Testing in Bariatric Surgery: How Far Should We Go?	6

Disorders of Gut-Brain Interaction in a National Cohort of Children With Down Syndrome	6
Retrograde Cricopharyngeus Dysfunction: Inability of Belch Due to Upper Esophageal Sphincter Relaxation Failure	6
Characteristics and Risk Factors of Functional Dyspepsia Fulfilling the Rome IV Criteria Overlapping With Gastroesophageal Reflux Disease, Irritable Bowel Syndrome, and Functional Constipation in Sout	6
Effect of Physical Activity on the Association Between Diet and Constipation: Evidence From the National Health and Nutrition Examination Survey 2007-2010	6
Usefulness of EndoFLIP in Diverticular Peroral Endoscopic Myotomy for Symptomatic Epiphrenic Diverticulum	5
Incidence and Clinical Course of Post-infectious Irritable Bowel Syndrome in Patients Admitted to University Hospitals: 1-year Prospective Follow-up Study	5
A Case of Emetophobia Responding to Mirtazapine and Propranolol Treatment	5
Type of Rectal Barostat Protocol Affects Classification of Hypersensitivity and Prediction of Symptom Severity in Irritable Bowel Syndrome	5
The Impact of a Twice-daily Versus Once-daily Proton Pump Inhibitor Dosing Regimen on Laryngopharyngeal Reflux Symptoms: A Prospective Randomized Controlled Trial	5
Assessment of Small Bowel Motility Using Cine-magnetic Resonance Imaging in Patients Suspected With Chronic Intestinal Pseudo-obstruction	5
Silent Struggles Within: Alexithymia Unveiled in Irritable Bowel Syndrome: A Systematic Review and Meta-analysis	5
Does Mean Nocturnal Baseline Impedance Play a Role in Managing Gastroesophageal Reflux Disease?	5
The Role of Psychological Factors in Noncardiac Chest Pain of Esophageal Origin	5
Imbalance of Innate and Adaptive Immunity in Esophageal Achalasia	5
Association of Proton Pump Inhibitor Use With Gastric Cancer in Regions With High Prevalence of Gastric Cancer: Systematic Review and Meta-analysis	5
Diagnosis of Ineffective Esophageal Motility According to Chicago Classification Version 4.0: More Stringent Criteria, but Also New Difficulties	4
Transient Gastric Pressure Elevation Synergizing With Impaired Esophagogastric Junction Barrier Function Plays a Pivotal Role in the Refractory Gastroesophageal Reflux Disease	4
Modern Achalasia: Diagnosis, Classification, and Treatment	4
Deciphering the Immune Complexity of Esophageal Achalasia	4
Is Mean Basal Esophagogastric Junction Pressure a Simpler and More Reliable Marker for Gastroesophageal Reflux Disease Barrier Function?	4
Age- and Sex-dependent Effects of High-fructose, High-fat Diets on Small Bowel Inflammation and Hepatic Steatosis in F344 Rats	4
Concise Review: Applicability of High-resolution Manometry in Gastroesophageal Reflux Disease	4
Association Between Caffeine Intake and Stool Frequency- or Consistency-Defined Constipation: Data From the National Health and Nutrition Examination Survey 2005-2010	4
Gastroesophageal Reflux Characteristics in Supragastric Belching Patients With Positive Versus Negative pH Monitoring: An Evidence of Secondary Gastroesophageal Reflux Disease From Excessive Belching	4
Nighttime Acid Reflux in Gastroesophageal Reflux Disease - Is It a Problem That Can Be Solved?	4
Loss of Inspiratory Augmentation as a Predictive Factor for the Development of Gastroesophageal Reflux Disease After Peroral Endoscopic Myotomy in Patients With Achalasia	4
Association Between Functional Dyspepsia and Binge Eating Disorder: A Frequent, Often Overlooked Overlap Clinical Presentation	4
Duodenojejunal Manometric Abnormalities in a Patient With Mesenterium Commune	4
Intracolonic Administration of Mosapride Citrate Significantly Increases Colonic Motility Compared With Oral Administration	4
The Effect of Clostridium butyricum on Gut Microbial Changes and Functional Profiles of Metabolism in High-fat Diet–fed Rats Depending on Age and Sex	4
Narcotic Bowel Syndrome, an Under-recognized Cause of Chronic Abdominal Pain in Adults	4
Stigma and Efficacy of Zhizhu Kuanzhong Capsules Versus Doxepin in the Treatment of Refractory Functional Dyspepsia: A Randomized Controlled Trial	4
Optimizing Assessment of Contraction Reserve in Ineffective Esophageal Motility: A Study of Upright Multiple Rapid Swallows	4
Effect of Trimebutine and Rifaximin on Breath Hydrogen and Methane by Glucose Breath Test in Patients With Functional Bloating: A Randomized Double-blind Clinical Trial	3
Rapid Progression of Nonspecific Esophageal Motor Disorder to Type II Achalasia and Recovery of Peristalsis After Pneumatic Dilation	3
Efficacy of Amitriptyline in Irritable Bowel Syndrome: A Systematic Review and Meta-analysis	3
Lactase Deficiency Diagnosed by Endoscopic Biopsy-based Method is Associated With Positivity to Glucose Breath Test	3
Real-world Prescription Patterns and Patient Satisfaction Regarding Maintenance Therapy of Gastroesophageal Reflux Disease: An Observational, Cross-sectional, Multicenter Study	3
Clinicians’ Knowledge, Attitudes, and Practices Towards Neuromodulators and Psychological Treatment in Functional Gastrointestinal Disorders - Do They Know?	3
The Disease Spectrum and Natural History of Patients With Abdominal Bloating or Distension: A Longitudinal Study	3
Clinical Guidance and Practical Recommendations for Probiotic Use in Patients With Irritable Bowel Syndrome, Functional Constipation, and Clostridioides difficile	3
Esophageal Mucosal Impedance Assessment: Clinical Usefulness for Diagnosis of Gastroesophageal Reflux Disease	3
The Effects of Physical Activity on Functional Dyspepsia: A Mendelian Randomization and Randomized Controlled Study	3
Delayed Gastric Emptying Correlates With Decreased Post-prandial Motility in Children: A Single-center Retrospective Review	3
Inflammation and Impaired Gut Physiology in Post-operative Ileus: Mechanisms and the Treatment Options	3
Prevalence of Irritable Bowel Syndrome in East Asia: Are There Differences Between Countries?	3
Neural Gastric Electrical Stimulation: Future Prospects in Managing Gastric Emptying Disorders	3
Overlap Between Gastroesophageal Reflux Disease and Functional Dyspepsia: Do We Need a New Management Paradigm?	3
Additional Diagnostic Yield of the Rapid Drink Challenge in Chicago Classification Version 4.0 Compared With Version 3.0	3
Bridging the Therapeutic Gap: Clinical Efficacy of Endoscopic Radiofrequency Stretta Therapy for Gastroesophageal Reflux Disease in Korea	3
Esophageal Hypocontractile Disorders and Hiatal Hernia Size Are Predictors for Long Segment Barrett’s Esophagus	3
Amitriptyline for the Treatment of Extra-esophageal Symptoms in Proton Pump Inhibitor-refractory Patients With Suspected Gastroesophageal Reflux Disease	3
Functional Dyspepsia and Gastric Emptying Scintigraphy: Why 4-Hour Imaging and a 255-kcal Meal Matter	3
Is Fecal Microbiota Transplantation Applicable for the Treatment of Irritable Bowel Syndrome? Time for Precision Medicine	3
The Prevalence and Characteristics of Symptomatic Uncomplicated Diverticular Disease Among Asian Patients With Unexplained Abdominal Symptoms	3
Effect of Helicobacter pylori Eradication on Body Weight: A Multicenter Propensity Score-matched Analysis in Korea	3
2025 Focused Update of the Seoul Consensus on Gastroesophageal Reflux Disease: Evidence-based Recommendations on Acid Suppressive Therapy	3
Surgical and Therapeutic Interventions for Chronic Intestinal Pseudo-obstruction: A Scoping Review	3
Phrenic Ampulla Emptying Dysfunction: Unveiling the Role of Lower Esophageal Sphincter After-contraction	2
Machine Learning Clustering Identifies Achalasia-Spectrum Phenotypes in Distal Esophageal Spasm	2
Nutrient Drink Test to Assess Gastric Accommodation in Cyclic Vomiting Syndrome: Single-blinded Parallel Grouped Prospective Study	2
Reinterpreting Amitriptyline in Extra-esophageal Gastroesophageal Reflux Disease Through the GABAergic Inhibitory Axis	2
Comparison of Diagnosis of Esophageal Motility Disorders by Chicago Classification Versions 3.0 and 4.0	2
Opioid-induced Constipation: Old and New Concepts in Diagnosis and Treatment	2
The Conundrum of Obesity and Gastroparesis Hospitalizations: A Retrospective Comparative Analysis of Hospitalization Characteristics and Disparities Amongst Socioeconomic and Racial Backgrounds in the	2
Long-term Effects of Potassium-competitive Acid Blockers and Proton Pump Inhibitors on Gastrin, Gastric Emptying Rate, and Small Intestinal Microbiota in Rats	2
Real‑world Application of the International Anorectal Physiology Working Group Standardized Protocol and London Classification: A Multi‑country Cross‑sectional Survey of Anorectal Manometry Practice i	2
The Effect of STW5 (Iberogast) on Reflux Symptoms in Patients With Concurrent Dyspeptic Symptoms: A Double-blind Randomized Placebo-controlled Crossover Trial	2
2025 Seoul Consensus on Clinical Practice Guidelines for Irritable Bowel Syndrome	2
Retrograde Cricopharyngeus Dysfunction, a New Motility Disorder: Single Center Case Series and Treatment Results	2
Dysphagia is Associated With the Combination of Defective Bolus Transit and Poorly Relaxing Lower Esophageal Sphincter in Patients With Ineffective Esophageal Motility	2
Clinical Characteristics and Associated Factors in Mexican Patients With Cyclic Vomiting Syndrome and Cannabinoid Hyperemesis Syndrome	2
Interpretation of Impedance Data on High-resolution Impedance Manometry Studies—A Worldwide Survey	2
Esophageal Mucosal Impedance Assessment for the Diagnosis of Gastroesophageal Reflux Disease	2
Symptomatic Response to Antibiotics in Patients With Small Intestinal Bacterial Overgrowth: A Systematic Review and Meta-analysis	2
Three-dimensional Anorectal Manometry in a Patient With Passive Fecal Incontinence and a History of Complex Perianal Fistula Treated With Fistulectomy	2
Comparison of Clinical Characteristics and Long-term Prognosis of Focal Hypoganglionosis With Adult-onset Megacolon and Chronic Intestinal Pseudo-obstruction	2