OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Pharmaceutical Investigation is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Advancements in Uricase formulations: overcoming therapeutic challenges in enzyme replacement therapy	117
Oligonucleotide therapeutics and their chemical modification strategies for clinical applications	96
Design of experiment (DoE)-based formulation design of bepotastine sustained-release tablet and in vitro-in vivo pharmacokinetic correlation	67
Enhanced oral bioavailability of pranlukast by preparing amorphous solid dispersion via hot-melt extrusion	55
Exploring pharmacokinetics and herb-drug interactions of an herbal extract mixture derived from Poria cocos and Morus alba L.	53
Nitric oxide-releasing albumin nanoclusters facilitate healing of methicillin-resistant Staphylococcus aureus-infected cutaneous wounds	41
Current advances and future perspectives of fattigation technology in pharmaceutical sciences and drug delivery	41
Development of nano-immunotherapy for cancer treatment: achievements and scopes	37
Examining the effect of spatial distribution of disintegrant particles on tablet disintegratability	37
Preformulation and evaluation of multi-layer tablets	36
Strategies for developing Alzheimer’s disease treatments: application of population pharmacokinetic and pharmacodynamic models	33
Recent studies on modulating hyaluronic acid-based hydrogels for controlled drug delivery	31
Quality by design approach to the development of transdermal patch systems and regulatory perspective	28
Erythromycin dermal delivery by MoS2 nanoflakes	28
An economically advantageous amorphous solid dispersion of the fixed combination of lopinavir and ritonavir	28
Tricaprin as a membrane permeability regulator: sustained small hydrophilic substance release from liposomes	27
3D-printed chitosan-pectin-sodium alginate scaffolds for post-surgical peritoneal wound dressing and sustained delivery of oxaliplatin	25
A precise look at electrospinning parameters in fabricating the polymeric nanofibers: a review on synthetic and natural polymers	22
Establishment of a fexofenadine population pharmacokinetic (PK)–pharmacodynamic (PD) model and exploration of dosing regimens through simulation	22
Application of continuous manufacturing for solid oral dosage forms	21
Fabrication of aerosol-based nanoparticles and their applications in biomedical fields	21
Tumor spheroid-based microtumor models for preclinical evaluation of anticancer nanomedicines	21
Development of clindamycin-loaded alginate/pectin/hyaluronic acid composite hydrogel film for the treatment of MRSA-infected wounds	20
pH-sensitive beads containing curcumin loaded nanostructured lipid carriers for a colon targeted oral delivery system	18
Lyotropic liquid crystalline nanoparticles for oral delivery: formulation and evaluation of sustained-released cromolyn sodium loaded cubosomes	18

Development of prediction model with machine learning in continuous twin screw granulation	18
A quality by design approach in oral extended release drug delivery systems: where we are and where we are going?	18
Wound dressing using graphene quantum dots: a proof of concept	17
Mitigating off-target distribution and enhancing cytotoxicity in breast cancer cells with alpha-ketoglutaric acid-modified Fe/Mg-CA nanoparticles	16
Nitric oxide-releasing albumin/chondroitin sulfate bioadhesive dressing for the treatment of MRSA-infected wounds	16
Peptide permeation enhancers for improving oral bioavailability of macromolecules	15
Catalase-mimicking synthetic nano-enzymes can reduce lipopolysaccharide-induced reactive oxygen generation and promote rapid detection of hydrogen peroxide and l-cysteine	15
A mechanism-based understanding of altered drug pharmacokinetics by gut microbiota	14
Progress and recent trends in photodynamic therapy with nanoparticles	14
Effects of telmisartan and perindopril combination on hypertension and cardiovascular damage	14
Antimicrobial strategies for topical biofilm-based wound infections: past, present, and future	13
Recent advances in albumin nanoparticle-based cancer therapies	13
In vivo pharmacokinetic and pharmacodynamic study of inhalable pirfenidone microparticles prepared via high-energy bead milling	13
Layered double hydroxide Pickering emulsion with enhanced skin penetration and photostability for psoriasis treatment	13
AICAR-loaded and panitumumab conjugated nanoparticles downregulate the expression of PD-L1 and enhance antitumor responses against ovarian cancer through the AMPK/STAT3 axis	13
Development and in vitro/in vivo evaluation of a nanosponge formulation loaded with Boswellia carterii oil extracts for the enhanced anti-inflammatory activity for the management of respiratory allerg	13
Developmental strategy for swellable/erodible matrix tablet of mirabegron: quality by design approach with various geometric properties and pharmacokinetic evaluation	12
Ultra deformable vesicles for boosting transdermal delivery of 2-arylpropionic acid class drug for management of musculoskeletal pain	12
Transdermal fluocinolone acetonide loaded decorated hyalurosomes cellulose acetate/polycaprolactone nanofibers mitigated Freund’s adjuvant-induced rheumatoid arthritis in rats	12
A review of glucoregulatory hormones potentially applicable to the treatment of Alzheimer’s disease: mechanism and brain delivery	12
Emerging trends in quantum dot-based photosensitizers for enhanced photodynamic therapy in cancer treatment	12
A population pharmacokinetic model for individualized regimens of finasteride according to CYP3A5 genotype and liver function	11
Multicompartmental pharmacokinetic evaluation of enavogliflozin eye drop formulation: Understanding its distribution to posterior segments	11
Nanomedicine approaches for medulloblastoma therapy	11
Effect of gastric residence time on the oral absorption of rebamipide sustained-release tablets in beagle dogs	11
Microneedle systems for delivering nucleic acid drugs	11
Advancements of hot-melt extrusion technology to address unmet patient needs and pharmaceutical quality aspects	10
Layered silicate nanoparticles as a non-injectable drug delivery system for biomacromolecules	10
Recent quality by design approaches for process optimization and quality enhancement of dry powder inhalers	10