OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Pharmaceutical Investigation is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Nitric oxide-releasing albumin/chondroitin sulfate bioadhesive dressing for the treatment of MRSA-infected wounds	140
Effects of telmisartan and perindopril combination on hypertension and cardiovascular damage	130
Development of prediction model with machine learning in continuous twin screw granulation	73
Enhanced oral bioavailability of pranlukast by preparing amorphous solid dispersion via hot-melt extrusion	67
Early pharmacokinetic evaluation of anti-tubercular treatment as a good indicator of treatment success in pulmonary tuberculosis patients on a retreatment regimen	45
The combination of HDACi encapsulated liposomal vaccines with oncolytic peptide QR-KLU induces an immune-mediated abscopal effect for cancer immunotherapy	40
Microneedle systems for delivering nucleic acid drugs	39
Recent advances in Alzheimer’s disease pathogenesis and therapeutics from an immune perspective	37
Recent advances in 3D cell culture models in cancer drug development	36
Comprehensive review in continuous direct compression process	35
Dose-independent pharmacokinetics of loganin in rats: effect of intestinal first-pass metabolism on bioavailability	33
Biocompatible biodegradable polymeric nanocarriers in dry powder inhalers (DPIs) for pulmonary inhalation delivery	31
Prediction of the pharmacokinetics of the GLP-1 receptor agonist semaglutide in humans via a population pharmacokinetic model integrating interspecies scaling	30
uPAR-targeted senolytic delivery to enhance cancer therapy	27
Organic clay-based fast dissolving microneedles for efficient transdermal delivery of therapeutic proteins	27
Lyophilization of pharmaceuticals: an overview and practical approaches for developing the lyophilization cycle	25
Pharmacokinetic modulation of substrate drugs via the inhibition of drug-metabolizing enzymes and transporters using pharmaceutical excipients	23
Formulation of secretome derived from mesenchymal stem cells for inflammatory skin diseases	22
Recent progress in drying technologies for improving the stability and delivery efficiency of biopharmaceuticals	22
A two-step design of experiments approach to investigate the simultaneous effects of ion-pairing and chemical enhancers to improve the permeability of lornoxicam in a topical hydrogel patch	21
An approach for identifying in silico peptides against authentic metabolites: in vitro characterization of thymosin β4 metabolites	20
Evaluating the effect of cationic peptide K16ApoE against Staphylococcus epidermidis biofilms	20
Enhanced oral bioavailability of megestrol acetate via polymer-hybridized solid lipid nanoparticles using ultrasonic nebulization method	19
Effects of red ginseng extract on the pharmacokinetics and disposition of warfarin via intestinal Cyp2c11 modulation in rats	19
A comprehensive review on different approaches for tumor targeting using nanocarriers and recent developments with special focus on multifunctional approaches	19

Transferrin modified PEG–PLGA nanoparticles: highly effective notoginsenoside R1 formulations for the treatment of ulcerative colitis	18
Strategies for developing Alzheimer’s disease treatments: application of population pharmacokinetic and pharmacodynamic models	18
Gold nanoparticles prevent the establishment of severe malaria in a murine animal model	18
Preformulation and evaluation of multi-layer tablets	17
Topical nanomedicines using lipids, carbohydrates, proteins, and synthetic polymers for enhanced management of skin disorders	17
Antimicrobial strategies for topical biofilm-based wound infections: past, present, and future	16
Strategic design and clinical evaluation of a fixed-dose combination tablet comprising valsartan, amlodipine, rosuvastatin and ezetimibe for patients with hypertension and dyslipidemia	15
Development of clindamycin-loaded alginate/pectin/hyaluronic acid composite hydrogel film for the treatment of MRSA-infected wounds	15
Ultra deformable vesicles for boosting transdermal delivery of 2-arylpropionic acid class drug for management of musculoskeletal pain	15
Indocyanine green-loaded microspheres as a near-infrared fluorescence marker for long-term localization of tumor sites	14
A population pharmacokinetic model for individualized regimens of finasteride according to CYP3A5 genotype and liver function	14
Advancements of hot-melt extrusion technology to address unmet patient needs and pharmaceutical quality aspects	13
Emerging trends in quantum dot-based photosensitizers for enhanced photodynamic therapy in cancer treatment	13
Polysaccharide-based platforms for nasal delivery: design, features, and perspectives	13
Development and in vitro/in vivo evaluation of a nanosponge formulation loaded with Boswellia carterii oil extracts for the enhanced anti-inflammatory activity for the management of respiratory allerg	13
Tumor extracellular vesicles carrying antitumor (KLAKLAK)2 peptide and tumor-specific antigens for improved tumor therapy	13
Dissociation mechanics and stability of type A botulinum neurotoxin complex by means of biophysical evaluation	12
Injectable hydrogel systems for local cancer therapy	12
Oral bioavailability enhancement of chrysin using a spray-dried solid dispersion formulation with sodium dodecyl sulfate and polyvinylpyrrolidone	12
Alginate-coated chitosan nanoparticles protect protein drugs from acid degradation in gastric media	11
Cationic lipid nanoparticles for nucleic acid delivery: microfluidics versus thin film hydration	11
Multifunctional lipidic nanocarriers for effective therapy of glioblastoma: recent advances in stimuli-responsive, receptor and subcellular targeted approaches	11
Novel microneedle patches for transdermal delivery of AP39, a hydrogen sulphide donor, in the treatment of scenarios mimicking neurological disorders	11
Recent advancements in lipid–mRNA nanoparticles as a treatment option for cancer immunotherapy	11
Current trends in inhaled pharmaceuticals: challenges and opportunities in respiratory infections treatment	10
Ophthalmic dosage forms for drug delivery to posterior segment	10
Safety of applying influenza-antigen-coated microneedles to rat skin and the antigen specific immune response in vivo	10
Integration of modern science into herbal medicine: application of pharmacokinetic-pharmacodynamic modeling in understanding nonclinical study of Cinnamomum cassia extract.	10
Development and evaluation of flurbiprofen plasters	10
Development of core–shell structured nanoparticle for sequential release of tariquidar and docetaxel to overcome multi drug-resistant cancer	10
Formulation of sustained-release orodispersible film containing drug–resin complexes of donepezil hydrochloride	9
Iron oxide nanoparticles-loaded hydrogels for effective topical photothermal treatment of skin cancer	9
A review of recent advances in nanotechnology for the delivery of therapeutics in wound healing	9
The combined effects of telmisartan and ramipril on hypertension and cardiovascular injury	9
Population pharmacokinetic analysis of lornoxicam in healthy Korean males considering creatinine clearance and CYP2C9 genetic polymorphism	9
ROS-activated prodrug nano-assemblies based on cinnamaldehyde-modified paclitaxel for treating breast cancer	9
Advanced technology using supercritical fluid for particle production in pharmaceutical continuous manufacturing	9