OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Pharmaceutical Analysis is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Structural basis of SARS-CoV-2 3CLpro and anti-COVID-19 drug discovery from medicinal plants	599
Structural elucidation of SARS-CoV-2 vital proteins: Computational methods reveal potential drug candidates against main protease, Nsp12 polymerase and Nsp13 helicase	188
Printability–A key issue in extrusion-based bioprinting	107
Plant-derived secondary metabolites as the main source of efflux pump inhibitors and methods for identification	86
Curcumin encapsulated dual cross linked sodium alginate/montmorillonite polymeric composite beads for controlled drug delivery	85
Multidisciplinary strategies to enhance therapeutic effects of flavonoids from Epimedii Folium: Integration of herbal medicine, enzyme engineering, and nanotechnology	70
Recent advances in quantum dots-based biosensors for antibiotics detection	60
Challenges for cysteamine stabilization, quantification, and biological effects improvement	55
Interactions between gut microbiota and berberine, a necessary procedure to understand the mechanisms of berberine	54
Development of chromatographic technologies for the quality control of Traditional Chinese Medicine in the Chinese Pharmacopoeia	52
Current status and future directions of high-throughput ADME screening in drug discovery	51
Offline two-dimensional liquid chromatography coupled with ion mobility-quadrupole time-of-flight mass spectrometry enabling four-dimensional separation and characterization of the multicomponents fro	51
Towards wearable and implantable continuous drug monitoring: A review	50
Phytochemicals targeting NF-κB signaling: Potential anti-cancer interventions	48
Carbon dots derived from Poria cocos polysaccharide as an effective “on-off” fluorescence sensor for chromium (VI) detection	47
Chemically modified carbon-based electrodes for the determination of paracetamol in drugs and biological samples	47
Discovery of human coronaviruses pan-papain-like protease inhibitors using computational approaches	46
Development of the general chapters of the Chinese Pharmacopoeia 2020 edition: A review	46
Recent advances in research on vine tea, a potential and functional herbal tea with dihydromyricetin and myricetin as major bioactive compounds	44
Physicochemical degradation of phycocyanin and means to improve its stability: A short review	42
The current status of anti-GPCR drugs against different cancers	41
Current LC-MS-based strategies for characterization and quantification of antibody-drug conjugates	40
Tumor cell membrane-coated continuous electrochemical sensor for GLUT1 inhibitor screening	39
Solid phase microextraction chemical biopsy tool for monitoring of doxorubicin residue during in vivo lung chemo-perfusion	39
Bi2O3/ZnO nanocomposite: Synthesis, characterizations and its application in electrochemical detection of balofloxacin as an anti-biotic drug	39

Screening strategies for quorum sensing inhibitors in combating bacterial infections	38
Antiviral, immunomodulatory, and anticoagulant effects of quercetin and its derivatives: Potential role in prevention and management of COVID-19	36
Electrochemical detection of methyl-paraoxon based on bifunctional cerium oxide nanozyme with catalytic activity and signal amplification effect	36
Qualitative and quantitative evaluation of Flos Puerariae by using chemical fingerprint in combination with chemometrics method	34
Anti-inflammatory and analgesic properties of Moroccan medicinal plants: Phytochemistry, in vitro and in vivo investigations, mechanism insights, clinical evidences and perspectives	33
Potential treatment with Chinese and Western medicine targeting NSP14 of SARS-CoV-2	33
Current status of in vivo bioanalysis of nano drug delivery systems	33
Neuroprotective effects of Ginkgo biloba dropping pills in Parkinson’s disease	32
Solid and liquid state characterization of tetrahydrocurcumin using XRPD, FT-IR, DSC, TGA, LC-MS, GC-MS, and NMR and its biological activities	32
A sensitive electrochemical detection of metronidazole in synthetic serum and urine samples using low-cost screen-printed electrodes modified with reduced graphene oxide and C60	32
Magnetic metal organic framework for pre-concentration of ampicillin from cow milk samples	31
Machine learning empowered COVID-19 patient monitoring using non-contact sensing: An extensive review	31
Biocompatible silver nanoparticles: An investigation into their protein binding efficacies, anti-bacterial effects and cell cytotoxicity studies	30
Current developments of bioanalytical sample preparation techniques in pharmaceuticals	29
Catalysis-based specific detection and inhibition of tyrosinase and their application	28
Antimicrobial activity and mode of action of terpene linalyl anthranilate against carbapenemase-producing Klebsiella pneumoniae	28
Polysaccharide-based chromatographic adsorbents for virus purification and viral clearance	28
Evaluation of apoptotic effects of mPEG-b-PLGA coated iron oxide nanoparticles as a eupatorin carrier on DU-145 and LNCaP human prostate cancer cell lines	28
An ultra-robust fingerprinting method for quality assessment of traditional Chinese medicine using multiple reaction monitoring mass spectrometry	27
Multimodal integrated strategy for the discovery and identification of quality markers in traditional Chinese medicine	27
Fluorescence imaging of drug target proteins using chemical probes	26
Qualitative analysis of chemical components in Lianhua Qingwen capsule by HPLC-Q Exactive-Orbitrap-MS coupled with GC-MS	26
Recent advances in construction of small molecule-based fluorophore-drug conjugates	26
Transformation of berberine to its demethylated metabolites by the CYP51 enzyme in the gut microbiota	26
Dispersive liquid-liquid microextraction, an effective tool for the determination of synthetic cannabinoids in oral fluid by liquid chromatography–tandem mass spectrometry	25
A carbon nanoparticle-peptide fluorescent sensor custom-made for simple and sensitive detection of trypsin	24
Applications and challenges of low temperature plasma in pharmaceutical field	24
Identification and quantification of the bioactive components in Osmanthus fragrans roots by HPLC-MS/MS	23
Lipidomics reveals carnitine palmitoyltransferase 1C protects cancer cells from lipotoxicity and senescence	23
Overoxidized poly(3,4-ethylenedioxythiophene)–gold nanoparticles–graphene-modified electrode for the simultaneous detection of dopamine and uric acid in the presence of ascorbic acid	23
Fluorescent antibiotics for real-time tracking of pathogenic bacteria	23
Comparative pharmacokinetics of six major compounds in normal and insomnia rats after oral administration of Ziziphi Spinosae Semen aqueous extract	22
TGA/Chemometrics addressing innovative preparation strategies for functionalized carbon nanotubes	21
Rabdosia serra alleviates dextran sulfate sodium salt-induced colitis in mice through anti-inflammation, regulating Th17/Treg balance, maintaining intestinal barrier integrity, and modulating gut micr	21
Diallyl disulfide and diallyl trisulfide in garlic as novel therapeutic agents to overcome drug resistance in breast cancer	20
Comparison of different approaches for direct coupling of solid-phase microextraction to mass spectrometry for drugs of abuse analysis in plasma	20
A dual-signal sensor for the analysis of parathion-methyl using silver nanoparticles modified with graphitic carbon nitride	19
Capillary electrophoresis methods for impurity profiling of drugs: A review of the past decade	19
A pyrene-based ratiometric fluorescent probe with a large Stokes shift for selective detection of hydrogen peroxide in living cells	19
RETRACTED: A DNA-based nanocarrier for efficient cancer therapy	19
Neutrophil elastase: From mechanisms to therapeutic potential	18
Molecular detection of SARS-CoV-2 being challenged by virus variation and asymptomatic infection	18
Nitrogen-doped carbon@TiO2 double-shelled hollow spheres as an electrochemical sensor for simultaneous determination of dopamine and paracetamol in human serum and saliva	18
Comparative analysis of constitutes and metabolites for traditional Chinese medicine using IDA and SWATH data acquisition modes on LC-Q-TOF MS	18
Microneedle-based interstitial fluid extraction for drug analysis: Advances, challenges, and prospects	18
Metabolomic and elemental profiling of blood serum in bladder cancer	18
Celastrol targeting Nedd4 reduces Nrf2-mediated oxidative stress in astrocytes after ischemic stroke	17
Accurate and sensitive determination of hydroxychloroquine sulfate used on COVID-19 patients in human urine, serum and saliva samples by GC-MS	17
Diversity, novelty, antimicrobial activity, and new antibiotics of cultivable endophytic actinobacteria isolated from psammophytes collected from Taklamakan Desert	17
Liquid chromatographic methods for determination of the new antiepileptic drugs stiripentol, retigabine, rufinamide and perampanel: A comprehensive and critical review	17

Determination of bioactive components in the fruits of Cercis chinensis Bunge by HPLC-MS/MS and quality evaluation by principal components and hierarchical cluster analyses	17
Synthesis and electrochemical properties of environmental free l-glutathione grafted graphene oxide/ZnO nanocomposite for highly selective piroxicam sensing	16
The potential of miRNA-based therapeutics in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection: A review	16
Vancomycin pretreatment attenuates acetaminophen-induced liver injury through 2-hydroxybutyric acid	16
Fluorescent aptasensor for detection of live foodborne pathogens based on multicolor perovskite-quantum-dot-encoded DNA probes and dual-stirring-bar-assisted signal amplification	16
An LC-MS/MS method for simultaneous analysis of the cystic fibrosis therapeutic drugs colistin, ivacaftor and ciprofloxacin	16
Integrative multi-omics and systems bioinformatics in translational neuroscience: A data mining perspective	15
Design and preparation of a new multi-targeted drug delivery system using multifunctional nanoparticles for co-delivery of siRNA and paclitaxel	15
Automatic analytical approach for the determination of 12 illicit drugs and nicotine metabolites in wastewater using on-line SPE-UHPLC-MS/MS	15
Study of intracellular anabolism of 5-fluorouracil and incorporation in nucleic acids based on an LC-HRMS method	15
Recent progress in the molecular imaging of therapeutic monoclonal antibodies	15
DNA barcoding in herbal medicine: Retrospective and prospective	15
Reversible regulation of enzyme-like activity of molybdenum disulfide quantum dots for colorimetric pharmaceutical analysis	15
Development of an analytical method for multi-residue quantification of 18 anthelmintics in various animal-based food products using liquid chromatography-tandem mass spectrometry	15
Metabolomics-based comparative analysis of the effects of host and environment on Viscum coloratum metabolites and antioxidative activities	15
Electrochemical, spectroscopic, and molecular docking studies of the interaction between the anti-retroviral drug indinavir and dsDNA	15
Drug repurposing against coronavirus disease 2019 (COVID-19): A review	14
Sensitive detection of microRNAs using polyadenine-mediated fluorescent spherical nucleic acids and a microfluidic electrokinetic signal amplification chip	14
Single-run reversed-phase HPLC method for determining sertraline content, enantiomeric purity, and related substances in drug substance and finished product	14
Predicting the grades of Astragali radix using mass spectrometry-based metabolomics and machine learning	14
Highly sensitive electrochemical determination of rutin based on the synergistic effect of 3D porous carbon and cobalt tungstate nanosheets	14
Pharmacokinetics, distribution, and excretion of sodium oligomannate, a recently approved anti-Alzheimer's disease drug in China	14
A strategy of screening and binding analysis of bioactive components from traditional Chinese medicine based on surface plasmon resonance biosensor	14
In situ synthesis of a spherical covalent organic framework as a stationary phase for capillary electrochromatography	13
MIL-53-based homochiral metal-organic framework as a stationary phase for open-tubular capillary electrochromatography	13
18beta-glycyrrhetinic acid induces ROS-mediated apoptosis to ameliorate hepatic fibrosis by targeting PRDX1/2 in activated HSCs	13
Development of a radiolabeled site-specific single-domain antibody positron emission tomography probe for monitoring PD-L1 expression in cancer	13
Erythrocyte sphingolipid species as biomarkers of Alzheimer's disease	13
An ultra-sensitive and easy-to-use assay for sensing human UGT1A1 activities in biological systems	12
Discovery of human pancreatic lipase inhibitors from root of Rhodiola crenulata via integrating bioactivity-guided fractionation, chemical profiling and biochemical assay	12
Detection and quantitation of host cell proteins in monoclonal antibody drug products using automated sample preparation and data-independent acquisition LC-MS/MS	12
Resveratrol elongates the lifespan and improves antioxidant activity in the silkworm Bombyx mori	12
UHPLC-MS/MS analysis of cAMP and cGMP in rat plasma as potential biomarkers of Yin-Yang disharmony in traditional Chinese medicine	12
Identification of potential anti-pneumonia pharmacological components of Glycyrrhizae Radix et Rhizoma after the treatment with Gan An He Ji oral liquid	12
Ginsenoside Rk3 is a novel PI3K/AKT-targeting therapeutics agent that regulates autophagy and apoptosis in hepatocellular carcinoma	12
Three-dimensional aspects of formulation excipients in drug discovery: a critical assessment on orphan excipients, matrix effects and drug interactions	12
Natural product-based radiopharmaceuticals: Focus on curcumin and its analogs, flavonoids, and marine peptides	12
Human islet amyloid polypeptide: A therapeutic target for the management of type 2 diabetes mellitus	11
Applications and safety of gold nanoparticles as therapeutic devices in clinical trials	11
Impaired tricarboxylic acid cycle flux and mitochondrial aerobic respiration during isoproterenol induced myocardial ischemia is rescued by bilobalide	11
Rapid detection of high-risk HPV16 and HPV18 based on microchip electrophoresis	11
Current diagnostic and therapeutic strategies for COVID-19	11
Angiotensin-converting enzyme 2 as a potential therapeutic target for COVID-19: A review	11
Reducing SARS-CoV-2 pathological protein activity with small molecules	11
Probing the degradation of pharmaceuticals in urine using MFC and studying their removal efficiency by UPLC-MS/MS	11
A simplified LC-MS/MS method for the quantification of the cardiovascular disease biomarker trimethylamine-N-oxide and its precursors	11
Taxifolin stability: In silico prediction and in vitro degradation with HPLC-UV/UPLC–ESI-MS monitoring	11
Compatibility and stability studies involving polymers used in fused deposition modeling 3D printing of medicines	11
Strategies for PET imaging of the receptor for advanced glycation endproducts (RAGE)	11
Simultaneous enantioseparation and simulation studies of atenolol, metoprolol and propranolol on Chiralpak® IG column using supercritical fluid chromatography	11
Plasma-metabolite-based machine learning is a promising diagnostic approach for esophageal squamous cell carcinoma investigation	10
Novel assays for quality evaluation of XueBiJing: Quality variability of a Chinese herbal injection for sepsis management	10
Metabolomic fingerprinting of porcine lung tissue during pre-clinical prolonged ex vivo lung perfusion using in vivo SPME coupled with LC-HRMS	10
Boosting ferroptosis and microtubule inhibition for antitumor therapy via a carrier-free supermolecule nanoreactor	10
Visualizing the spatial distribution and alteration of metabolites in continuously cropped Salvia miltiorrhiza Bge using MALDI-MSI	10
A highly efficient protein corona-based proteomic analysis strategy for the discovery of pharmacodynamic biomarkers	10
An integrated strategy for comprehensive characterization of metabolites and metabolic profiles of bufadienolides from Venenum Bufonis in rats	10
Long-chain alkanol–alkyl carboxylic acid-based low-viscosity hydrophobic deep eutectic solvents for one-pot extraction of anthraquinones from Rhei Radix et Rhizoma	10
Screening of the whole human cytochrome P450 complement (CYPome) with enzyme bag cocktails	10
Fabrication of edge-curled petals-like covalent organic frameworks and their properties for extracting indole alkaloids from complex biological samples	10
Development of a CLDN18.2-targeting immuno-PET probe for non-invasive imaging in gastrointestinal tumors	10