Virulence

Article	Citations
Anti-HBc IgM associates with acute flare and HBeAg/HBsAg loss in chronic hepatitis B patients with acute exacerbation	340
STA regulates succinylated AflM triggered by SCS to contribute to aflatoxin biosynthesis through the Ach1	140
Predicting the evolutionary and epidemiological dynamics of SARS-CoV-2 in South Africa	102
EefR mutations drive sanguinarine resistance by activating cryptic multidrug efflux pumps in AcrB-Null Escherichia coli	97
Study of the relationships among known virulence genes, coccoid transformation and cytotoxicity of Helicobacter pylori in different clinical diseases	96
Oropouche virus: Understanding “sloth fever” disease dynamics and novel intervention strategies against this emerging neglected tropical disease	95
Understanding the prevalence of SARS-CoV-2 (COVID-19) exposure in companion, captive, wild, and farmed animals	74
Recombination events drives the emergence of Colombian Helicobacter pylori subpopulations with self-identity ancestry	69
Pathogenicity and virulence of henipaviruses	69
Letter to the editor (response to Vajro and colleagues)	67
Correction	63
Streptococcus pyogenes emm 98.1 variants activate inflammatory caspases in human neutrophils	62
Glycogen synthase kinase 3 promotes the proliferation of porcine epidemic diarrhoea virus by phosphorylating the nucleocapsid protein	58
Comparison of Omicron and respiratory virus infections in pediatric liver transplantation: Impact of perioperative identification status	57
A. caviae infection triggers IL-1β secretion through activating NLRP3 inflammasome mediated by NF-κB signaling pathway partly in a TLR2 dependent manner	55
Convergent and divergent roles of the glucose-responsive kinase SNF4 in Candida tropicalis	54
Usingin vivotranscriptomics and RNA enrichment to identify genes involved in virulence ofCandida glabrata	54
A new gene family (BAPs) of Cotesia bracovirus induces apoptosis of host hemocytes	53
Pathogenesis and virulence of Heartland virus	52
Pathogenicity and virulence of O’nyong-nyong virus: A less studied Togaviridae with pandemic potential	51
Pathogenicity and virulence of influenza	51
Comparative genomic and virulence analyses of a novel sequence type 420 Streptococcus equi subspecies zooepidemicus isolated from donkey	49
Ferroptosis is important for Toxoplasma gondii replication and virulence in vitro and in vivo	47
Statistical analysis supports UTR (untranslated region) deletion theory in SARS-CoV-2	47
Genetic insights into the interaction between chronic hepatitis B virus infection and metabolic syndrome	47

Ctr9 promotes virulence of Candida albicans by regulating methionine metabolism	45
Molecular epidemiology of Nakaseomyces glabrata associated with vulvovaginal candidiasis revealed high genetic variability and the presence of novel genotypes in China	45
Host cell transcriptomic response to the multidrug-resistant Mycobacterium tuberculosis clonal outbreak Beijing strain reveals its pathogenic features	45
Inhibitory effects of a maleimide compound on the virulence factors of Candida albicans	45
Protection acquired upon intraperitoneal group a Streptococcus immunization is independent of concurrent adaptive immune responses but relies on macrophages and IFN-γ	44
Type 2 hypersensitivity disorders, including systemic lupus erythematosus, Sjögren’s syndrome, Graves’ disease, myasthenia gravis, immune thrombocytopenia, autoimmune hemolytic anemia, dermatomyositis	41
Prevalence and clinical significance of HBeAg-positive chronic hepatitis B patients with and without anti-HBe antibody	40
Plant pathogens provide clues to the potential origin of bat white-nose syndrome Pseudogymnoascus destructans	40
Streptococcus suis serotype 5: Emerging zoonotic threat with distinct genomic heterogeneity	39
Comparative transcriptomic analysis reveal genes involved in the pathogenicity increase of Streptococcus suis epidemic strains	37
Hidden liver-joint axis: HBV infection causes rheumatoid arthritis via TRAFD1 with imbalance of HBV X protein and trans-ferulic acid	37
Pathogenicity and virulence of Francisella tularensis	36
Carbon source-driven downregulation of the sRNA AmiL enhances Pseudomonas aeruginosa virulence during acute lung infection	36
Virulence and transmission characteristics of clade 2.3.4.4b H5N6 subtype avian influenza viruses possessing different internal gene constellations	35
A promising endeavor against human cytomegalovirus: Predominant epitopes-based recombinant subunit vaccine RH Ec IE1/pp65/pp150	34
Changes in gene expression levels caused by H3K9me3/H3K9ac modifications are associated with BmCPV infection in Bombyx mori	34
Serum proteases prevent bacterial biofilm formation: role of kallikrein and plasmin	32
Carnosol attenuates Acinetobacter baumannii virulence by interfering with indole-mediated quorum sensing	32
Autophagy-driven modulation of stem cell dynamics in Helicobacter pylori -induced gastric diseases in mice	31
Synergistic host-parasitoid antimicrobial peptide interactions ensure the survival of parasitized hosts	29
Proteomic characterization of Aspergillus fumigatus – host interactions using the ex-vivo pig lung (EVPL) model	29
Investigating the differential microRNAs expression in young and aged Drosophila melanogaster following Flock House Virus infection	29
Porcine cGAS-STING signalling induced apoptosis negatively regulates STING downstream IFN response and autophagy via different mechanisms	27
Hemocyanin controls Vibrio levels in hemolymph by modulating intracellular ROS via p38 MAPK	26
Identification of miR-29a as a novel biomarker for lumpy skin disease virus exposure in cattle	26
Evolution of Mycobacterium abscessus in the human lung: Cumulative mutations and genomic rearrangement of porin genes in patient isolates	25
Alpha1-antitrypsin impacts innate host–pathogen interactions with Candida albicans by stimulating fungal filamentation	25
Langya henipavirus: Is it a potential cause for public health concern?	25
Glycosylation of viral proteins: Implication in virus–host interaction and virulence	24
A temperate Siphoviridae bacteriophage isolate from Siberian tiger enhances the virulence of methicillin-resistant Staphylococcus	24
Stenotrophomonas maltophilia of clinical origin display higher temperature tolerance comparing with environmental isolates	23
An updated review of HSV-1 infection-associated diseases and treatment, vaccine development, and vector therapy application	23
MALDI-TOF MS for rapid detection and differentiation between Tet(X)-producers and non-Tet(X)-producing tetracycline-resistant Gram-negative bacteria	23
NagZ modulates the virulence of E. cloacae by acting through the gene of unknown function, ECL_03795	22
QX-type infectious bronchitis virus infection in roosters can seriously injure the reproductive system and cause sex hormone secretion disorder	22
SARS-CoV-2 shedding dynamics and transmission in immunosuppressed patients	22
Innovative use of gram-positive enhancer matrix particles and affinity peptides in a vaccine against Coxsackievirus B3	22
Fluorescence-based biosensors for West Nile virus detection	22
Methyltransferase K-D-K-E motif influences the intercellular transmission of Newcastle disease virus	22
The characteristics of TCR CDR3 repertoire in COVID-19 patients and SARS-CoV-2 vaccine recipients	22
The multiple roles of viral 3D pol protein in picornavirus infections	22
Detection of Clostridium sporogenes in a Roman-era cattle mass grave at Vilauba	21
Organelles are miscommunicating: Membrane contact sites getting hijacked by pathogens	20
PHB2 affects the virulence of Vip3Aa to Sf9 cells through internalization and mitochondrial stability	20
Emerging West African Genotype Chikungunya Virus in Mosquito Virome	20
Mechanisms of Talaromyces marneffei induced CNS injury: Synergistic roles of tauopathy, pyroptosis, and microglial inflammation	20
A Drosophila melanogaster model shows that fast growing Metarhizium species are the deadliest despite eliciting a strong immune response	20
Pathogenicity and virulence of Brucella : Strategies for metabolic adaptation and immune evasion	19
Pathogenicity and virulence of Mycoplasma genitalium: Unraveling Ariadne’s Thread	19
Genomic characterization, transcriptome analysis, and pathogenicity of the Nipah virus (Indian isolate)	19

Review of human pegivirus: Prevalence, transmission, pathogenesis, and clinical implication	19
Pathogenicity and virulence of malaria: Sticky problems and tricky solutions	19
Cyanidin chloride protects mice from methicillin-resistant Staphylococcus aureus-induced pneumonia by targeting Sortase A	19
Protective efficacy of a novel recombinant influenza virus carrying partial human metapneumovirus F protein epitopes	18
Characterization and genomic insights into bacteriophages Kpph1 and Kpph9 against hypervirulent carbapenem-resistant Klebsiella pneumoniae	18
Hepatitis B core-related antigen serum levels may be a predictor of acute flare of chronic hepatitis B among pregnant women in the immune-tolerant phase of chronic HBV infection after short-course ant	18
Effects of α and β-adrenergic signaling on innate immunity and Porphyromonas gingivalis virulence in an invertebrate model	18
Effects of Isaria cateniannulata on the colonization process and enzyme activity of Fagopyrum tataricum seeds during germination	18
The multifaceted interactions between Newcastle disease virus proteins and host proteins: a systematic review	18
Analysis of HIV-1 subtypes and drug resistance mutations in people who inject drugs in Aizawl and nearby districts of Mizoram, India	18
Microbiological control for mosquito larvae: Current progress and applications	17
Immunoevasion strategies for African swine fever virus: Modulation of antigen presentation pathways	17
The role of multi-omics in the diagnosis of COVID-19 and the prediction of new therapeutic targets	17
Bactericidal and anti-quorum sensing activity of repurposing drug Visomitin against Staphylococcus aureus	17
Ohmyungsamycin promotes M1-like inflammatory responses to enhance host defence against Mycobacteroides abscessus infections	17
The pathogenicity and virulence of the opportunistic pathogen Staphylococcus epidermidis	16
Chlamydia psittaci : A zoonotic pathogen causing avian chlamydiosis and psittacosis	16
The molybdate transport protein ModA regulates nitrate reductase activity to increase the intestinal colonization and extraintestinal dissemination of Klebsiella pneumoniae	16
Peptostreptococcus Anaerobius enhances dextran sulfate sodium-induced colitis by promoting nf-κB-NLRP3-Dependent macrophage pyroptosis	16
Pathogenicity and virulence of monkeypox at the human-animal-ecology interface	16
Iron depletion has different consequences on the growth and survival of Toxoplasma gondii strains	16
Alongshan virus: An emerging arboviral challenge in regional health security	15
The role of glutathione for oxidative stress and pathogenicity of Streptococcus suis	15
Neutrophil extracellular trap-borne C3-driven endothelial dysfunction in Klebsiella pneumoniae liver abscess	15
A shared mechanism of multidrug resistance in laboratory-evolved uropathogenic Escherichia coli	15
High frequency of CD8 escape mutations in elite controllers as new obstacle for HIV cure	15
Interplay of Mycobacterium abscessus and Pseudomonas aeruginosa in experimental models of coinfection: Biofilm dynamics and host immune re	15
Correction	15
AoVps18 regulates sporulation, trap morphogenesis, and nematode predation by modulating vacuole assembly and attractant synthesis in Arthrobotrys oligospora	15
Roles and mechanisms of gapA and gap -encoded proteins in cronobacter sakazakii adhesion to and invasion of	15
Porcine reproductive and respiratory syndrome virus infects the reproductive system of male piglets and impairs development of the blood–testis barrier	15
Epithelial cell invasion by salmonella typhimurium induces modulation of genes controlled by aryl hydrocarbon receptor signaling and involved in extracellular matrix bio	15
Tobramycin-resistant small colony variant mutant of Salmonella enterica serovar Typhimurium shows collateral sensitivity to nitrofurantoin	15
Recent Discoveries of Novel Mammarenaviruses Infecting Humans and Other Mammals in Asia and Southeast Asia	15
Intracellular survival of Staphylococcus aureus in macrophages during osteomyelitis	15
Decarboxylase mediated oxalic acid metabolism is important to antioxidation and detoxification rather than pathogenicity in Magnaporthe oryzae	14
Emergence of Staphylococcus argenteus in pediatrics: Molecular insights from a hospital in East China	14
Ferroptosis and macrophage efferocytosis in periodontitis: Biological insights and therapeutic advances	14
Comparative transcriptome combined with morphophysiological analyses revealed the molecular mechanism underlying Tetrahymena thermophila predation-induced antiphage defense in Aeromonas hydr	14
Sucrose non-fermenting protein kinase gene UvSnf1 is required for virulence in Ustilaginoidea virens	14
Balancing harm and harmony: Evolutionary dynamics between gut microbiota-derived flagellin and TLR5-mediated host immunity and metabolism	14
Screening optimal DC-targeting peptide to enhance the immune efficacy of recombinant Lactobacillus expressing RHDV VP60	14
Intratumorally specific microbial-derived lipopolysaccharide contributes to non-small cell lung cancer progression	14
Helicobacter pylori East Asian type CagA hijacks more SHIP2 by its EPIYA-D motif to potentiate the oncogenicity	14
Porphyromonas gulae and canine periodontal disease: Current understanding and future directions	14
ATP synthase subunit ATP5B interacts with TGEV Nsp2 and acts as a negative regulator of TGEV replication	14
The F 1 F o -ATP synthase α subunit of Candida albicans induces inflammatory responses by controlli	13
Ixchiq (VLA1553): The first FDA-approved vaccine to prevent disease caused by Chikungunya virus infection	13
A human intestinal organoid derived from fetal human colon cells model for studying enteroviral pathogenesis	13
The Hog1-Nmd5 signaling pathway regulates asexual development, lipid metabolism, stress response, trap morphogenesis, and secondary metabolism of Arthrobotrys oligospora	13
It’s time to act: Understanding and combating Vibrio vulnificus	13
Novel avian metapneumovirus subtype C variant is a newly emerged pathogen causing hydrosalpinx fluid syndrome in Sheldrake ducks in China	13
The CueR-regulated transporters CopA and CusFABC coordinate copper detoxification in Vibrio parahaemolyticus	13
Circulated echovirus 18 strains in Guangdong Province and worldwide: A novel perspective on genetic diversity and recombination patterns	13
Talaromyces marneffei activates the AIM2-caspase-1/-4-GSDMD axis to induce pyroptosis in hepatocytes	13
Physiological role of bicarbonate in microbes: A double-edged sword?	13
Preliminary assessment of the therapeutic potential of staphylococcal enterotoxin-like W via biological activity and TCR binding sites analysis	13
SARS-CoV-2 versus other minor viral infection on kidney injury in asymptomatic and mildly symptomatic patients	13
Pathogenicity and virulence of Borrelia burgdorferi	13
UvVelC is important for conidiation and pathogenicity in the rice false smut pathogen Ustilaginoidea virens	12
Annexin A2: the missing piece in the puzzle of pathogen-induced damage	12
A distinct variant of the SzM protein of Streptococcus equi subsp. zooepidemicus recruits C1q independent of IgG binding and inhibits acti	12
Culture breakthrough enables goose circovirus (GoCV) isolation and pathogenic gosling modeling to uncover the association between viral infection and vaccine failure	12
Functionality of the human antibody response to Candida albicans	12
Multi-omics profiling of acute Pseudomonas aeruginosa pneumonia unmasks conventional NK cell depletion and stage-specific therapeutic targets	12
Loss and gain of ceftazidime-avibactam susceptibility in a non-carbapenemase-producing K1-ST23 hypervirulent Klebsiella pneumoniae	12
Exogenous proline promotes serum killing of Klebsiella pneumoniae	11
A novel aquaporin Aagp contributes to Streptococcus suis H 2 O 2 efflux and virulence	11
Correction	11
Multiple HA substitutions in highly pathogenic avian influenza H5Nx viruses contributed to the change in the NA subtype preference	11
IFNL4 genotype influences the rate of HIV-1 seroconversion in men who have sex with men	11
HIF-1α interacting with miR-2013-3p regulates pathogen-induced energy production changes via targeting glutamate dehydrogenase in the sea urchin Strongylocentrotus intermedius	11
RPLP1, an NS4B-interacting protein, enhances production of CSFV through promoting translation of viral genome	11
Exogenous NADH promotes the bactericidal effect of aminoglycoside antibiotics against Edwardsiella tarda	11
The urinary microbiome distinguishes symptomatic urinary tract infection from asymptomatic older adult patients presenting to the emergency department	11
Comprehensive diagnostic approaches to feline toxoplasmosis: Bridging traditional methods and emerging technologies	11
Exploring the role of multi-pathogen infections in Alzheimer’s disease: A case–control study	11
H1N1 influenza virus dose dependent induction of dysregulated innate immune responses and STAT1/3 activation are associated with pulmonary immunopathological damage	11
ABO blood group is involved in the quality of the specific immune response anti-SARS-CoV-2	11
Role of riboflavin biosynthesis gene duplication and transporter in Aeromonas salmonicida virulence in marine teleost fish	11

A systematic survey of type I secretion systems and their substrate proteins in Salmonella	11
Tilmicosin inhibits the infections of currently prevalent porcine reproductive and respiratory syndrome viruses via the downregulation of CD163 expression	10
Staphylococcus aureus planktonic but not biofilm environment induces an IFN-β macrophage immune response via the STING/IRF3 pathway	10
Comparative secretome analysis of Staphylococcus aureus strains with different within-herd intramammary infection prevalence	10
Nomogram for evaluating obvious liver inflammation in treatment-naïve HBeAg positive chronic hepatitis B virus infection patients with normal ALT	10
Arginine depletion-induced autophagy and metabolic dysregulation are involved in the disease severity of hand, foot, and mouth disease	10
Herpes simplex virus interference with immunity: Focus on dendritic cells	10
Recent global outbreaks of highly pathogenic and low-pathogenicity avian influenza A virus infections	10
Macrophage innate immune responses delineate between defective translocon assemblies produced by Yersinia pseudotuberculosis YopD mutants	10
Deciphering the immunomodulatory cross-talk: Bacterial extracellular vesicles in gut homeostasis	10
Liver–joint axis: Hepatitis B virus as a contributor to rheumatoid arthritis pathogenesis	10
Emergence and molecular evolution of carbapenem-resistant hypervirulent ST23 Klebsiella pneumoniae : The superbug phenomenon in China	10
Disruption of CmHmgr1 triggers apoptosis and causes defects in growth, conidiogenesis, and mycoparasitism of Coniothyrium minitans	10
Xylose utilization promotes Salmonella replication within macrophages and systemic infection in mice	9
Klebsiella pneumoniae derived outer membrane vesicles mediated bacterial virulence, antibiotic resistance, host immune responses and clinical applications	9
The spectrum of clinical biomarkers in severe malaria and new avenues for exploration	9
Protoporphyrin IX targets viral spike glycoproteins to inactivate Akabane virus	9
Blood virome profiling reveals subtype-specific viral signatures and reduced diversity in non-Hodgkin lymphoma	9
Pathogenicity and Virulence of Coxiella burnetii: Focus on Q fever	9
Artemisinin displays bactericidal activity via copper-mediated DNA damage	9
Pathogenicity and virulence of Helicobacter pylori : A paradigm of chronic infection	9
Humoral responses to multiple SARS-CoV-2 variants after two doses of vaccine in kidney transplant patients	9
Staphylococcus aureus nt5 gene mutation through CRISPR RNA-guided base editing weakens bacterial virulence and immune evasion	9
Pathogenicity and virulence of Chlamydia trachomatis : Insights into host interactions, immune evasion, and intracellular survival	9
Iron metabolism contributes to virulence by enhancing serum resistance in the emerging high-risk clone ST15 CRKP	9
Correction	9
Pathogenicity and virulence of Marburg virus	9
The pathogenicity and virulence of Leishmania - interplay of virulence factors with host defenses	9
Honey-derived Paenibacillus spp. with potential to affect bee brood development in Apis mellifera : Are they a new threat to honey bees?	9
Multifaceted roles of NADPH oxidases in the growth and pathogenicity of Beauveria bassiana	9
Mannan is a context-dependent shield that modifies virulence in Nakaseomyces glabratus	9
LncRNA transcriptome analysis of rainbow trout ( Oncorhynchus mykiss ) skin infected with IHNV reveals that lncRNA SARL/miR-205-z/ SOCS3 a	9