Virulence

Article	Citations
Oropouche virus: Understanding “sloth fever” disease dynamics and novel intervention strategies against this emerging neglected tropical disease	250
Correction	205
Pathogenesis and virulence of Heartland virus	117
Letter to the editor (response to Vajro and colleagues)	94
Understanding the prevalence of SARS-CoV-2 (COVID-19) exposure in companion, captive, wild, and farmed animals	87
Usingin vivotranscriptomics and RNA enrichment to identify genes involved in virulence ofCandida glabrata	83
Streptococcus pyogenes emm 98.1 variants activate inflammatory caspases in human neutrophils	78
Study of the host specificity of PB1-F2-associated virulence	76
A new gene family (BAPs) of Cotesia bracovirus induces apoptosis of host hemocytes	69
Deciphering of Candida parapsilosis induced immune response in Drosophila melanogaster	67
Recombination events drives the emergence of Colombian Helicobacter pylori subpopulations with self-identity ancestry	61
Study of the relationships among known virulence genes, coccoid transformation and cytotoxicity of Helicobacter pylori in different clinical diseases	59
Convergent and divergent roles of the glucose-responsive kinase SNF4 in Candida tropicalis	57
A. caviae infection triggers IL-1β secretion through activating NLRP3 inflammasome mediated by NF-κB signaling pathway partly in a TLR2 dependent manner	57
Establishing an invertebrate Galleria mellonella greater wax moth larval model of Neisseria gonorrhoeae infection	50
Pathogenicity and virulence of O’nyong-nyong virus: A less studied Togaviridae with pandemic potential	47
Identification of Streptococcus suis putative zoonotic virulence factors: A systematic review and genomic meta-analysis	47
Orientin mediates protection against MRSA-induced pneumonia by inhibiting Sortase A	45
Pathogenicity and virulence of influenza	45
Pathogenicity and virulence of henipaviruses	44
Plant pathogens provide clues to the potential origin of bat white-nose syndrome Pseudogymnoascus destructans	43
Statistical analysis supports UTR (untranslated region) deletion theory in SARS-CoV-2	43
Inhibitory effects of a maleimide compound on the virulence factors of Candida albicans	43
Protection acquired upon intraperitoneal group a Streptococcus immunization is independent of concurrent adaptive immune responses but relies on macrophages and IFN-γ	42
Comparative transcriptomic analysis reveal genes involved in the pathogenicity increase of Streptococcus suis epidemic strains	42

Type 2 hypersensitivity disorders, including systemic lupus erythematosus, Sjögren’s syndrome, Graves’ disease, myasthenia gravis, immune thrombocytopenia, autoimmune hemolytic anemia, dermatomyositis	42
Virulence and transmission characteristics of clade 2.3.4.4b H5N6 subtype avian influenza viruses possessing different internal gene constellations	42
A phage protein-derived antipathogenic peptide that targets type IV pilus assembly	41
Host cell transcriptomic response to the multidrug-resistant Mycobacterium tuberculosis clonal outbreak Beijing strain reveals its pathogenic features	40
Hidden liver-joint axis: HBV infection causes rheumatoid arthritis via TRAFD1 with imbalance of HBV X protein and trans-ferulic acid	39
Decreased temperature increases the expression of a disordered bacterial late embryogenesis abundant (LEA) protein that enhances natural transformation	37
Ctr9 promotes virulence of Candida albicans by regulating methionine metabolism	37
Pathogenicity and virulence of Francisella tularensis	36
Evolution of Mycobacterium abscessus in the human lung: Cumulative mutations and genomic rearrangement of porin genes in patient isolates	36
MALDI-TOF MS for rapid detection and differentiation between Tet(X)-producers and non-Tet(X)-producing tetracycline-resistant Gram-negative bacteria	35
Alpha1-antitrypsin impacts innate host–pathogen interactions with Candida albicans by stimulating fungal filamentation	35
Identification of miR-29a as a novel biomarker for lumpy skin disease virus exposure in cattle	34
Role of intestinal extracellular matrix-related signaling in porcine epidemic diarrhea virus infection	32
Serum proteases prevent bacterial biofilm formation: role of kallikrein and plasmin	32
A promising endeavor against human cytomegalovirus: Predominant epitopes-based recombinant subunit vaccine RH Ec IE1/pp65/pp150	32
The multiple roles of viral 3D pol protein in picornavirus infections	32
Adaptation of the emerging pathogenic yeast Candida auris to high caspofungin concentrations correlates with cell wall changes	31
Langya henipavirus: Is it a potential cause for public health concern?	31
QX-type infectious bronchitis virus infection in roosters can seriously injure the reproductive system and cause sex hormone secretion disorder	30
Glycosylation of viral proteins: Implication in virus–host interaction and virulence	28
A temperate Siphoviridae bacteriophage isolate from Siberian tiger enhances the virulence of methicillin-resistant Staphylococcus aureus through distinct mechanisms	27
SARS-CoV-2 shedding dynamics and transmission in immunosuppressed patients	27
Emerging West African Genotype Chikungunya Virus in Mosquito Virome	27
Methyltransferase K-D-K-E motif influences the intercellular transmission of Newcastle disease virus	27
NagZ modulates the virulence of E. cloacae by acting through the gene of unknown function, ECL_03795	27
An updated review of HSV-1 infection-associated diseases and treatment, vaccine development, and vector therapy application	27
PHB2 affects the virulence of Vip3Aa to Sf9 cells through internalization and mitochondrial stability	26
Modulating the host immune response to fight against COVID-19: Where are we in 2021?	26
Review of human pegivirus: Prevalence, transmission, pathogenesis, and clinical implication	26
Innovative use of gram-positive enhancer matrix particles and affinity peptides in a vaccine against coxsackievirus B3	25
Organelles are miscommunicating: Membrane contact sites getting hijacked by pathogens	25
The characteristics of TCR CDR3 repertoire in COVID-19 patients and SARS-CoV-2 vaccine recipients	25
Genomic characterization, transcriptome analysis, and pathogenicity of the Nipah virus (Indian isolate)	24
Transcriptome analysis of porcine PBMCs reveals lipopolysaccharide-induced immunomodulatory responses and crosstalk of immune and glucocorticoid receptor signaling	24
Pathogenicity and virulence of malaria: Sticky problems and tricky solutions	23
Cyanidin chloride protects mice from methicillin-resistant Staphylococcus aureus-induced pneumonia by targeting Sortase A	23
A Drosophila melanogaster model shows that fast growing Metarhizium species are the deadliest despite eliciting a strong immune response	23
Protective efficacy of a novel recombinant influenza virus carrying partial human metapneumovirus F protein epitopes	22
Effects of α and β-adrenergic signaling on innate immunity and Porphyromonas gingivalis virulence in an invertebrate model	22
Pathogenicity and virulence of Mycoplasma genitalium: Unraveling Ariadne’s Thread	22
The multifaceted interactions between Newcastle disease virus proteins and host proteins: a systematic review	21
Characterization and genomic insights into bacteriophages Kpph1 and Kpph9 against hypervirulent carbapenem-resistant Klebsiella pneumoniae	21
Hepatitis B core-related antigen serum levels may be a predictor of acute flare of chronic hepatitis B among pregnant women in the immune-tolerant phase of chronic HBV infection after short-course ant	21
Chlamydia psittaci : A zoonotic pathogen causing avian chlamydiosis and psittacosis	21
Exacerbation of Mycobacterium avium pulmonary infection by comorbid allergic asthma is associated with diminished mycobacterium-specific Th17 responses	21
Ohmyungsamycin promotes M1-like inflammatory responses to enhance host defence against Mycobacteroides abscessus infections	20
The molybdate transport protein ModA regulates nitrate reductase activity to increase the intestinal colonization and extraintestinal dissemination of Klebsiella pneumoniae	20
Analysis of HIV-1 subtypes and drug resistance mutations in people who inject drugs in Aizawl and nearby districts of Mizoram, India	20
COVID-19 variants as moving targets and how to stop them by glycoengineered whole-virus vaccines	20
Iron depletion has different consequences on the growth and survival of Toxoplasma gondii strains	20

Peptostreptococcus Anaerobius enhances dextran sulfate sodium-induced colitis by promoting nf-κB-NLRP3-Dependent macrophage pyroptosis	20
The pathogenicity and virulence of the opportunistic pathogen Staphylococcus epidermidis	20
Roles and mechanisms of gapA and gap -encoded proteins in cronobacter sakazakii adhesion to and invasion of	19
The role of glutathione for oxidative stress and pathogenicity of Streptococcus suis	19
Pathogenicity and virulence of monkeypox at the human-animal-ecology interface	19
Tobramycin-resistant small colony variant mutant of Salmonella enterica serovar Typhimurium shows collateral sensitivity to nitrofurantoin	19
The role of multi-omics in the diagnosis of COVID-19 and the prediction of new therapeutic targets	19
A shared mechanism of multidrug resistance in laboratory-evolved uropathogenic Escherichia coli	19
Correction	19
Bactericidal and anti-quorum sensing activity of repurposing drug Visomitin against Staphylococcus aureus	19
Epithelial cell invasion by salmonella typhimurium induces modulation of genes controlled by aryl hydrocarbon receptor signaling and involved in extracellular matrix bio	18
Interplay of mycobacterium abscessus and Pseudomonas aeruginosa in experimental models of coinfection: Biofilm dynamics and Host immune re	18
Porcine reproductive and respiratory syndrome virus infects the reproductive system of male piglets and impairs development of the blood–testis barrier	18
Pathogenicity and virulence ofListeria monocytogenes: A trip from environmental to medical microbiology	18
High frequency of CD8 escape mutations in elite controllers as new obstacle for HIV cure	18
Recent Discoveries of Novel Mammarenaviruses Infecting Humans and Other Mammals in Asia and Southeast Asia	18
Alongshan virus: An emerging arboviral challenge in regional health security	18
Helicobacter pylori East Asian type CagA hijacks more SHIP2 by its EPIYA-D motif to potentiate the oncogenicity	17
Sucrose non-fermenting protein kinase gene UvSnf1 is required for virulence in Ustilaginoidea virens	17
Synergy of alanine and gentamicin to reduce nitric oxide for elevating killing efficacy to antibiotic-resistant Vibrio alginolyticus	17
The F 1 F o -ATP synthase α subunit of Candida albicans induces inflammatory responses by controlli	17
Too young to die? How aging affects cellular innate immune responses to influenza virus and disease severity	17
The Hog1-Nmd5 signaling pathway regulates asexual development, lipid metabolism, stress response, trap morphogenesis, and secondary metabolism of Arthrobotrys oligospora	17
Transcriptional response ofAspergillus fumigatusto copper and the role of the Cu chaperones	17
Screening optimal DC-targeting peptide to enhance the immune efficacy of recombinant Lactobacillus expressing RHDV VP60	16
ATP synthase subunit ATP5B interacts with TGEV Nsp2 and acts as a negative regulator of TGEV replication	16
Physiological role of bicarbonate in microbes: A double-edged sword?	16
Porphyromonas gulae and canine periodontal disease: Current understanding and future directions	16
Comparative transcriptome combined with morphophysiological analyses revealed the molecular mechanism underlying Tetrahymena thermophila predation-induced antiphage defense in Aeromonas hydr	16
Decarboxylase mediated oxalic acid metabolism is important to antioxidation and detoxification rather than pathogenicity in Magnaporthe oryzae	15
Functional analysis of seven regulators of G protein signaling (RGSs) in the nematode-trapping fungus Arthrobotrys oligospora	15
Oral administration of Clostridium butyricum rescues streptomycin-exacerbated respiratory syncytial virus-induced lung inflammation in mice	15
Emergence of Staphylococcus argenteus in pediatrics: Molecular insights from a hospital in East China	15
Talaromyces marneffei activates the AIM2-caspase-1/-4-GSDMD axis to induce pyroptosis in hepatocytes	15
Developmental consequences of children born from mothers with telbivudine treatment during late pregnancy: A prospective study with 3-year follow-up	14
Functionality of the human antibody response to Candida albicans	14
SARS-CoV-2 versus other minor viral infection on kidney injury in asymptomatic and mildly symptomatic patients	14
Loss and gain of ceftazidime-avibactam susceptibility in a non-carbapenemase-producing K1-ST23 hypervirulent Klebsiella pneumoniae	14
Pathogenicity and virulence of Borrelia burgdorferi	14
RPLP1, an NS4B-interacting protein, enhances production of CSFV through promoting translation of viral genome	14
UvVelC is important for conidiation and pathogenicity in the rice false smut pathogen Ustilaginoidea virens	14
ABO blood group is involved in the quality of the specific immune response anti-SARS-CoV-2	14
Ixchiq (VLA1553): The first FDA-approved vaccine to prevent disease caused by Chikungunya virus infection	14
H1N1 influenza virus dose dependent induction of dysregulated innate immune responses and STAT1/3 activation are associated with pulmonary immunopathological damage	14
A distinct variant of the SzM protein of Streptococcus equi subsp. zooepidemicus recruits C1q independent of IgG binding and inhibits acti	14
Multi-omics profiling of acute Pseudomonas aeruginosa pneumonia unmasks conventional NK cell depletion and stage-specific therapeutic targets	13
HIF-1α interacting with miR-2013-3p regulates pathogen-induced energy production changes via targeting glutamate dehydrogenase in the sea urchin Strongylocentrotus intermedius	13
Exogenous NADH promotes the bactericidal effect of aminoglycoside antibiotics against Edwardsiella tarda	13
IFNL4 genotype influences the rate of HIV-1 seroconversion in men who have sex with men	13
Evaluation of hepatitis E antigen kinetics and its diagnostic utility for prediction of the outcomes of hepatitis E virus genotype 1 infection	13
A novel aquaporin Aagp contributes to Streptococcus suis H 2 O 2 efflux and virulence	13
Xylose utilization promotes Salmonella replication within macrophages and systemic infection in mice	13
Comparative secretome analysis of Staphylococcus aureus strains with different within-herd intramammary infection prevalence	13
Genetic diversification of persistent Mycobacterium abscessus within cystic fibrosis patients	13
Annexin A2: the missing piece in the puzzle of pathogen-induced damage	13
Insights into the molecular determinants involved in Mycobacterium tuberculosis persistence and their therapeutic implications	13
Nomogram for evaluating obvious liver inflammation in treatment-naïve HBeAg positive chronic hepatitis B virus infection patients with normal ALT	13
Correction	13
The spectrum of clinical biomarkers in severe malaria and new avenues for exploration	12
The pathogenicity and virulence of Leishmania - interplay of virulence factors with host defenses	12
Herpes simplex virus interference with immunity: Focus on dendritic cells	12
Artemisinin displays bactericidal activity via copper-mediated DNA damage	12
Arginine depletion-induced autophagy and metabolic dysregulation are involved in the disease severity of hand, foot, and mouth disease	12
Staphylococcus aureus planktonic but not biofilm environment induces an IFN-β macrophage immune response via the STING/IRF3 pathway	12
Role of riboflavin biosynthesis gene duplication and transporter in Aeromonas salmonicida virulence in marine teleost fish	12
Recent global outbreaks of highly pathogenic and low-pathogenicity avian influenza A virus infections	12
Multiple HA substitutions in highly pathogenic avian influenza H5Nx viruses contributed to the change in the NA subtype preference	12
Pathogenicity and virulence of Helicobacter pylori : A paradigm of chronic infection	12
Macrophage innate immune responses delineate between defective translocon assemblies produced by Yersinia pseudotuberculosis YopD mutants	12
Pathogenicity and virulence of Marburg virus	12
The journey of SARS-CoV-2 in human hosts: a review of immune responses, immunosuppression, and their consequences	12
A clubroot pathogen effector targets cruciferous cysteine proteases to suppress plant immunity	11
Adjuvants for Helicobacter pylori vaccines: Outer membrane vesicles provide an alternative strategy	11
Staphylococcus aureus nt5 gene mutation through CRISPR RNA-guided base editing weakens bacterial virulence and immune evasion	11
Correction	11
African swine fever virus protein p17 promotes mitophagy by facilitating the interaction of SQSTM1 with TOMM70	11
The SWC4 subunit of the SWR1 chromatin remodeling complex is involved in varying virulence ofMetarhizium brunneumisolates offering role of epigenetic regulation of pathogenicity	11
Multifaceted roles of NADPH oxidases in the growth and pathogenicity of Beauveria bassiana	11
Distinctive function of Tetraspanins: Implication in viral infections	11
Mannan is a context-dependent shield that modifies virulence in Nakaseomyces glabratus	11

A biological and genomic comparison of a drug-resistant and a drug-susceptible strain of Candida auris isolated from Beijing, China	11
Klebsiella pneumoniae derived outer membrane vesicles mediated bacterial virulence, antibiotic resistance, host immune responses and clinical applications	11
Talaromyces marneffei promotes M2-like polarization of human macrophages by downregulating SOCS3 expression and activating the TLR9 pathway	11
Time to positivity of Klebsiella pneumoniae in blood cultures as prognostic marker in patients with intra-abdominal infection: A retrospective study	11
Honey-derived Paenibacillus spp. with potential to affect bee brood development in Apis mellifera : Are they a new threat to honey bees?	11
The pathogenesis and virulence of enterovirus-D68 infection	11
Lactic acid in the vaginal milieu modulates the Candida -host interaction	11