Virulence

Papers
(The TQCC of Virulence is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Understanding the prevalence of SARS-CoV-2 (COVID-19) exposure in companion, captive, wild, and farmed animals290
Comparison of Omicron and respiratory virus infections in pediatric liver transplantation: Impact of perioperative identification status247
Recombination events drives the emergence of Colombian Helicobacter pylori subpopulations with self-identity ancestry139
A. caviae infection triggers IL-1β secretion through activating NLRP3 inflammasome mediated by NF-κB signaling pathway partly in a TLR2 dependent manner113
Deciphering of Candida parapsilosis induced immune response in Drosophila melanogaster97
Streptococcus pyogenes emm 98.1 variants activate inflammatory caspases in human neutrophils93
Pathogenicity and virulence of influenza89
A new gene family (BAPs) of Cotesia bracovirus induces apoptosis of host hemocytes82
Pathogenesis and virulence of Heartland virus79
Study of the relationships among known virulence genes, coccoid transformation and cytotoxicity of Helicobacter pylori in different clinical diseases76
Glycogen synthase kinase 3 promotes the proliferation of porcine epidemic diarrhoea virus by phosphorylating the nucleocapsid protein67
Predicting the evolutionary and epidemiological dynamics of SARS-CoV-2 in South Africa65
Convergent and divergent roles of the glucose-responsive kinase SNF4 in Candida tropicalis57
Correction54
Pathogenicity and virulence of henipaviruses53
Letter to the editor (response to Vajro and colleagues)51
Pathogenicity and virulence of O’nyong-nyong virus: A less studied Togaviridae with pandemic potential50
Oropouche virus: Understanding “sloth fever” disease dynamics and novel intervention strategies against this emerging neglected tropical disease50
Orientin mediates protection against MRSA-induced pneumonia by inhibiting Sortase A49
Usingin vivotranscriptomics and RNA enrichment to identify genes involved in virulence ofCandida glabrata49
Identification of Streptococcus suis putative zoonotic virulence factors: A systematic review and genomic meta-analysis49
Host cell transcriptomic response to the multidrug-resistant Mycobacterium tuberculosis clonal outbreak Beijing strain reveals its pathogenic features47
Statistical analysis supports UTR (untranslated region) deletion theory in SARS-CoV-247
Ferroptosis is important for Toxoplasma gondii replication and virulence in vitro and in vivo46
Plant pathogens provide clues to the potential origin of bat white-nose syndrome Pseudogymnoascus destructans45
Prevalence and clinical significance of HBeAg-positive chronic hepatitis B patients with and without anti-HBe antibody45
Type 2 hypersensitivity disorders, including systemic lupus erythematosus, Sjögren’s syndrome, Graves’ disease, myasthenia gravis, immune thrombocytopenia, autoimmune hemolytic anemia, dermatomyositis45
Protection acquired upon intraperitoneal group a Streptococcus immunization is independent of concurrent adaptive immune responses but relies on macrophages and IFN-γ44
Virulence and transmission characteristics of clade 2.3.4.4b H5N6 subtype avian influenza viruses possessing different internal gene constellations43
Hidden liver-joint axis: HBV infection causes rheumatoid arthritis via TRAFD1 with imbalance of HBV X protein and trans-ferulic acid42
Streptococcus suis serotype 5: Emerging zoonotic threat with distinct genomic heterogeneity41
Inhibitory effects of a maleimide compound on the virulence factors of Candida albicans40
Comparative genomic and virulence analyses of a novel sequence type 420 Streptococcus equi subspecies zooepidemicus isolated from donkey39
Ctr9 promotes virulence of Candida albicans by regulating methionine metabolism38
Comparative transcriptomic analysis reveal genes involved in the pathogenicity increase of Streptococcus suis epidemic strains38
Pathogenicity and virulence of Francisella tularensis36
A temperate Siphoviridae bacteriophage isolate from Siberian tiger enhances the virulence of methicillin-resistant Staphylococcus aureus through distinct mechanisms35
Serum proteases prevent bacterial biofilm formation: role of kallikrein and plasmin35
Role of intestinal extracellular matrix-related signaling in porcine epidemic diarrhea virus infection34
Proteomic characterization of Aspergillus fumigatus – host interactions using the ex-vivo pig lung (EVPL) model33
MALDI-TOF MS for rapid detection and differentiation between Tet(X)-producers and non-Tet(X)-producing tetracycline-resistant Gram-negative bacteria33
Carnosol attenuates Acinetobacter baumannii virulence by interfering with indole-mediated quorum sensing33
Evolution of Mycobacterium abscessus in the human lung: Cumulative mutations and genomic rearrangement of porin genes in patient isolates32
A promising endeavor against human cytomegalovirus: Predominant epitopes-based recombinant subunit vaccine RH Ec IE1/pp65/pp15031
Alpha1-antitrypsin impacts innate host–pathogen interactions with Candida albicans by stimulating fungal filamentation31
Langya henipavirus: Is it a potential cause for public health concern?31
The multiple roles of viral 3D pol protein in picornavirus infections31
Stenotrophomonas maltophilia of clinical origin display higher temperature tolerance comparing with environmental isolates30
Changes in gene expression levels caused by H3K9me3/H3K9ac modifications are associated with BmCPV infection in Bombyx mori30
An updated review of HSV-1 infection-associated diseases and treatment, vaccine development, and vector therapy application29
Identification of miR-29a as a novel biomarker for lumpy skin disease virus exposure in cattle29
Porcine cGAS-STING signalling induced apoptosis negatively regulates STING downstream IFN response and autophagy via different mechanisms28
QX-type infectious bronchitis virus infection in roosters can seriously injure the reproductive system and cause sex hormone secretion disorder28
Glycosylation of viral proteins: Implication in virus–host interaction and virulence27
Review of human pegivirus: Prevalence, transmission, pathogenesis, and clinical implication26
SARS-CoV-2 shedding dynamics and transmission in immunosuppressed patients25
Cyanidin chloride protects mice from methicillin-resistant Staphylococcus aureus-induced pneumonia by targeting Sortase A25
PHB2 affects the virulence of Vip3Aa to Sf9 cells through internalization and mitochondrial stability24
Pathogenicity and virulence of Mycoplasma genitalium: Unraveling Ariadne’s Thread24
The characteristics of TCR CDR3 repertoire in COVID-19 patients and SARS-CoV-2 vaccine recipients23
Methyltransferase K-D-K-E motif influences the intercellular transmission of Newcastle disease virus23
Innovative use of gram-positive enhancer matrix particles and affinity peptides in a vaccine against Coxsackievirus B323
NagZ modulates the virulence of E. cloacae by acting through the gene of unknown function, ECL_0379523
Emerging West African Genotype Chikungunya Virus in Mosquito Virome23
Pathogenicity and virulence of malaria: Sticky problems and tricky solutions22
Effects of α and β-adrenergic signaling on innate immunity and Porphyromonas gingivalis virulence in an invertebrate model22
Genomic characterization, transcriptome analysis, and pathogenicity of the Nipah virus (Indian isolate)22
A Drosophila melanogaster model shows that fast growing Metarhizium species are the deadliest despite eliciting a strong immune response22
Organelles are miscommunicating: Membrane contact sites getting hijacked by pathogens22
Exacerbation of Mycobacterium avium pulmonary infection by comorbid allergic asthma is associated with diminished mycobacterium-specific Th17 responses22
Peptostreptococcus Anaerobius enhances dextran sulfate sodium-induced colitis by promoting nf-κB-NLRP3-Dependent macrophage pyroptosis21
Ohmyungsamycin promotes M1-like inflammatory responses to enhance host defence against Mycobacteroides abscessus infections21
The role of multi-omics in the diagnosis of COVID-19 and the prediction of new therapeutic targets20
Characterization and genomic insights into bacteriophages Kpph1 and Kpph9 against hypervirulent carbapenem-resistant Klebsiella pneumoniae20
The molybdate transport protein ModA regulates nitrate reductase activity to increase the intestinal colonization and extraintestinal dissemination of Klebsiella pneumoniae 20
Chlamydia psittaci : A zoonotic pathogen causing avian chlamydiosis and psittacosis20
Protective efficacy of a novel recombinant influenza virus carrying partial human metapneumovirus F protein epitopes19
Pathogenicity and virulence of monkeypox at the human-animal-ecology interface19
The pathogenicity and virulence of the opportunistic pathogen Staphylococcus epidermidis19
Analysis of HIV-1 subtypes and drug resistance mutations in people who inject drugs in Aizawl and nearby districts of Mizoram, India19
Iron depletion has different consequences on the growth and survival of Toxoplasma gondii strains19
The multifaceted interactions between Newcastle disease virus proteins and host proteins: a systematic review19
Bactericidal and anti-quorum sensing activity of repurposing drug Visomitin against Staphylococcus aureus19
Roles and mechanisms of gapA and gap -encoded proteins in cronobacter sakazakii adhesion to and invasion of18
Hepatitis B core-related antigen serum levels may be a predictor of acute flare of chronic hepatitis B among pregnant women in the immune-tolerant phase of chronic HBV infection after short-course ant18
Pathogenicity and virulence ofListeria monocytogenes: A trip from environmental to medical microbiology18
Correction18
High frequency of CD8 escape mutations in elite controllers as new obstacle for HIV cure18
A shared mechanism of multidrug resistance in laboratory-evolved uropathogenic Escherichia coli17
Interplay of Mycobacterium abscessus and Pseudomonas aeruginosa in experimental models of coinfection: Biofilm dynamics and host immune re17
Alongshan virus: An emerging arboviral challenge in regional health security17
Tobramycin-resistant small colony variant mutant of Salmonella enterica serovar Typhimurium shows collateral sensitivity to nitrofurantoin17
Epithelial cell invasion by salmonella typhimurium induces modulation of genes controlled by aryl hydrocarbon receptor signaling and involved in extracellular matrix bio17
Recent Discoveries of Novel Mammarenaviruses Infecting Humans and Other Mammals in Asia and Southeast Asia17
The role of glutathione for oxidative stress and pathogenicity of Streptococcus suis17
Oral administration of Clostridium butyricum rescues streptomycin-exacerbated respiratory syncytial virus-induced lung inflammation in mice16
Porcine reproductive and respiratory syndrome virus infects the reproductive system of male piglets and impairs development of the blood–testis barrier16
Comparative transcriptome combined with morphophysiological analyses revealed the molecular mechanism underlying Tetrahymena thermophila predation-induced antiphage defense in Aeromonas hydr16
Talaromyces marneffei activates the AIM2-caspase-1/-4-GSDMD axis to induce pyroptosis in hepatocytes16
Screening optimal DC-targeting peptide to enhance the immune efficacy of recombinant Lactobacillus expressing RHDV VP6015
Pathogenicity and virulence of Borrelia burgdorferi15
Porphyromonas gulae and canine periodontal disease: Current understanding and future directions15
ATP synthase subunit ATP5B interacts with TGEV Nsp2 and acts as a negative regulator of TGEV replication15
Decarboxylase mediated oxalic acid metabolism is important to antioxidation and detoxification rather than pathogenicity in Magnaporthe oryzae15
Transcriptional response ofAspergillus fumigatusto copper and the role of the Cu chaperones15
Emergence of Staphylococcus argenteus in pediatrics: Molecular insights from a hospital in East China15
The Hog1-Nmd5 signaling pathway regulates asexual development, lipid metabolism, stress response, trap morphogenesis, and secondary metabolism of Arthrobotrys oligospora15
Sucrose non-fermenting protein kinase gene UvSnf1 is required for virulence in Ustilaginoidea virens14
Physiological role of bicarbonate in microbes: A double-edged sword?14
Ixchiq (VLA1553): The first FDA-approved vaccine to prevent disease caused by Chikungunya virus infection14
The F 1 F o -ATP synthase α subunit of Candida albicans induces inflammatory responses by controlli14
Balancing harm and harmony: Evolutionary dynamics between gut microbiota-derived flagellin and TLR5-mediated host immunity and metabolism14
Loss and gain of ceftazidime-avibactam susceptibility in a non-carbapenemase-producing K1-ST23 hypervirulent Klebsiella pneumoniae13
A novel aquaporin Aagp contributes to Streptococcus suis H 2 O 2 efflux and virulence13
RPLP1, an NS4B-interacting protein, enhances production of CSFV through promoting translation of viral genome13
Circulated echovirus 18 strains in Guangdong Province and worldwide: A novel perspective on genetic diversity and recombination patterns13
Exogenous NADH promotes the bactericidal effect of aminoglycoside antibiotics against Edwardsiella tarda13
Multi-omics profiling of acute Pseudomonas aeruginosa pneumonia unmasks conventional NK cell depletion and stage-specific therapeutic targets13
HIF-1α interacting with miR-2013-3p regulates pathogen-induced energy production changes via targeting glutamate dehydrogenase in the sea urchin Strongylocentrotus intermedius13
Functionality of the human antibody response to Candida albicans13
Insights into the molecular determinants involved in Mycobacterium tuberculosis persistence and their therapeutic implications13
SARS-CoV-2 versus other minor viral infection on kidney injury in asymptomatic and mildly symptomatic patients13
ABO blood group is involved in the quality of the specific immune response anti-SARS-CoV-213
UvVelC is important for conidiation and pathogenicity in the rice false smut pathogen Ustilaginoidea virens13
Annexin A2: the missing piece in the puzzle of pathogen-induced damage13
Helicobacter pylori East Asian type CagA hijacks more SHIP2 by its EPIYA-D motif to potentiate the oncogenicity13
Genetic diversification of persistent Mycobacterium abscessus within cystic fibrosis patients13
H1N1 influenza virus dose dependent induction of dysregulated innate immune responses and STAT1/3 activation are associated with pulmonary immunopathological damage13
A distinct variant of the SzM protein of Streptococcus equi subsp. zooepidemicus recruits C1q independent of IgG binding and inhibits acti13
Herpes simplex virus interference with immunity: Focus on dendritic cells12
The pathogenicity and virulence of Leishmania - interplay of virulence factors with host defenses12
The spectrum of clinical biomarkers in severe malaria and new avenues for exploration12
Role of riboflavin biosynthesis gene duplication and transporter in Aeromonas salmonicida virulence in marine teleost fish12
Klebsiella pneumoniae derived outer membrane vesicles mediated bacterial virulence, antibiotic resistance, host immune responses and clinical applications12
A human intestinal organoid derived from fetal human colon cells model for studying enteroviral pathogenesis12
A clubroot pathogen effector targets cruciferous cysteine proteases to suppress plant immunity12
Multiple HA substitutions in highly pathogenic avian influenza H5Nx viruses contributed to the change in the NA subtype preference12
Comparative secretome analysis of Staphylococcus aureus strains with different within-herd intramammary infection prevalence12
Nomogram for evaluating obvious liver inflammation in treatment-naïve HBeAg positive chronic hepatitis B virus infection patients with normal ALT12
Staphylococcus aureus planktonic but not biofilm environment induces an IFN-β macrophage immune response via the STING/IRF3 pathway12
IFNL4 genotype influences the rate of HIV-1 seroconversion in men who have sex with men12
A systematic survey of type I secretion systems and their substrate proteins in Salmonella12
Artemisinin displays bactericidal activity via copper-mediated DNA damage12
Disruption of CmHmgr1 triggers apoptosis and causes defects in growth, conidiogenesis, and mycoparasitism of Coniothyrium minitans12
Macrophage innate immune responses delineate between defective translocon assemblies produced by Yersinia pseudotuberculosis YopD mutants12
African swine fever virus protein p17 promotes mitophagy by facilitating the interaction of SQSTM1 with TOMM7011
Staphylococcus aureus nt5 gene mutation through CRISPR RNA-guided base editing weakens bacterial virulence and immune evasion11
Talaromyces marneffei promotes M2-like polarization of human macrophages by downregulating SOCS3 expression and activating the TLR9 pathway11
Arginine depletion-induced autophagy and metabolic dysregulation are involved in the disease severity of hand, foot, and mouth disease11
Pathogenicity and virulence of Marburg virus11
LncRNA transcriptome analysis of rainbow trout ( Oncorhynchus mykiss ) skin infected with IHNV reveals that lncRNA SARL/miR-205-z/ SOCS3 a11
Correction11
Adjuvants for Helicobacter pylori vaccines: Outer membrane vesicles provide an alternative strategy11
Recent global outbreaks of highly pathogenic and low-pathogenicity avian influenza A virus infections11
Xylose utilization promotes Salmonella replication within macrophages and systemic infection in mice11
The SWC4 subunit of the SWR1 chromatin remodeling complex is involved in varying virulence ofMetarhizium brunneumisolates offering role of epigenetic regulation of pathogenicity11
Multifaceted roles of NADPH oxidases in the growth and pathogenicity of Beauveria bassiana11
Honey-derived Paenibacillus spp. with potential to affect bee brood development in Apis mellifera : Are they a new threat to honey bees?11
Lactic acid in the vaginal milieu modulates the Candida -host interaction11
Correction11
Pathogenicity and virulence of Helicobacter pylori : A paradigm of chronic infection11
From environmental adaptation to host survival: Attributes that mediate pathogenicity of Candida auris11
Pathogenicity and Virulence of Coxiella burnetii: Focus on Q fever11
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