Aging and Disease

Article	Citations
Astrocyte-Microglia Crosstalk: A Novel Target for the Treatment of Migraine	236
Is the β Common Receptor the Key Molecule for the Protective Effect of Erythropoietin?	107
Vascular Contributions to Healthy Aging and Dementia	101
Neuropsychological Profiles in Genetic Frontotemporal Dementia: A Meta-Analysis and Systematic Review	77
Axonal Energy Crisis and Calcium Phosphate Dysregulation as Pathogenesis of Optic Disc Drusen	71
Protein Synthesis Errors and Longevity: A Lesson from a Single Amino Acid Mutation Study	70
The Roles of T cells in Immune Checkpoint Inhibitor-Induced Arthritis	64
The Role of the Redox Enzyme p66Shc in Biological Aging of the Lung	60
EP3 Receptor Deficiency Improves Vascular Remodeling and Cognitive Impairment in Cerebral Small Vessel Disease	58
KRT5+/p63+ Stem Cells Undergo Senescence in the Human Lung with Pathological Aging	56
Revisiting the Role of Mitochondrial DNA Mutations in Aging: Bridging Theoretical Expectations with Empirical Observations	54
Exploiting the Fractionation of Stable Isotopes in Biochemical Processes for Medical Diagnosis: A Narrative Review	53
Neuronal Intranuclear Inclusion Disease with NOTCH2NLC GGC Repeat Expansion: A Systematic Review and Challenges of Phenotypic Characterization	52
Aging-Related Sarcopenia: Metabolic Characteristics and Therapeutic Strategies	48
Lysine Malonylation and Its Links to Metabolism and Diseases	43
Vascular Aging and Atherosclerosis: A Perspective on Aging	43
Targeting Cellular Senescence in Aging and Age-Related Diseases: Challenges, Considerations, and the Emerging Role of Senolytic and Senomorphic Therapies	43
Neuroprotective Mechanisms of Puerarin in Central Nervous System Diseases: Update	43
Neuroinflammation as a Link in Parkinson’s and Alzheimer’s Diseases: A Systematic Review and Meta-Analysis	42
Perspectives on Movement and Eating Behaviours in Brazilian Elderly: An Analysis of Clusters Associated with Disease Outcomes	41
Endogenous Retroviruses Unveiled: A Comprehensive Review of Inflammatory Signaling/Senescence-Related Pathways and Therapeutic Strategies	41
A Systematic Review of Intervention Trials Utilizing Biomarkers Among Informal Caregivers of People with Alzheimer's Disease & Related Dementias	41
Nanozyme-Based Strategies in Cancer Immunotherapy: Overcoming Resistance to Enhance Therapeutic Efficacy	40
Citicoline for Supporting Memory in Aging Humans	40
Age-related Loss of miR-124 Causes Cognitive Deficits via Derepressing RyR3 Expression	39

Role of AMPK and Sirtuins in Aging Heart: Basic and Translational Aspects	38
Current Animal Model Systems for Ovarian Aging Research	37
Healthy Human Fecal Microbiota Transplantation into Mice Attenuates MPTP-Induced Neurotoxicity via AMPK/SOD2 Pathway	37
Telomeres: Dysfunction, Maintenance, Aging and Cancer	36
Unmet Medication Needs and the Association with Mortality in Older Adults: Equality-Oriented Monitoring toward Universal Health Coverage	35
Autophagy in Disease Onset and Progression	33
Aging and “Age-Related” Diseases - What Is the Relation?	32
Normal Bone Matrix Mineralization but Altered Growth Plate Morphology in the LmnaG609G/G609G Mouse Model of Progeria	30
Decoding the Role of Familial Parkinson’s Disease-Related Genes in DNA Damage and Repair	30
EchoAGE: Echocardiography-based Neural Network Model Forecasting Heart Biological Age	30
Mitochondrial Dysfunction of Astrocytes Mediates Lipid Accumulation in Temporal Lobe Epilepsy	29
Role of Serotonylation and SERT Posttranslational Modifications in Alzheimer's Disease Pathogenesis	29
Exosomal Proteomics: Unveiling Novel Insights into Lung Cancer	29
Emerging Roles of Ceramide in Cardiovascular Diseases	28
New Clues to Cardiovascular Disease: Erythrocyte Lifespan	28
Epidural Pulsation Accelerates the Drainage of Brain Interstitial Fluid	28
Histone Methylation, Energy Metabolism, and Alzheimer's Disease	27
Elderly Dementia Needs Better Care in Post-COVID-19 Era	27
Different Aspects of Aging in Migraine	27
Repurposing Ketamine in the Therapy of Depression and Depression-Related Disorders: Recent Advances and Future Potential	26
The Potential Role of Cytokines in Diabetic Intervertebral Disc Degeneration	26
Revisiting Skeletal Muscle Dysfunction and Exercise in Chronic Obstructive Pulmonary Disease: Emerging Significance of Myokines	26
Fecal Microbiota Transplantation Attenuates Frailty via Gut-Muscle Axis in Old Mice	25
Chronobiology of the Tumor Microenvironment: Implications for Therapeutic Strategies and Circadian-Based Interventions	25
Role of Microglia, Decreased Neurogenesis and Oligodendrocyte Depletion in Long COVID-Mediated Brain Impairments	25
Mortality Outcomes in a Large Population with and without Covert Cerebrovascular Disease	25
Intestinal Flora: A Potential New Regulator of Cardiovascular Disease	25
SARM1 Promotes Neurodegeneration and Memory Impairment in Mouse Models of Alzheimer's Disease	25
Mitochondrial Dysfunction: A Roadmap for Understanding and Tackling Cardiovascular Aging	24
Clinical Potential of Immunotherapies in Subarachnoid Hemorrhage Treatment: Mechanistic Dissection of Innate and Adaptive Immune Responses	24
Semaphorins: Missing Signals in Age-dependent Alteration of Neuromuscular Junctions and Skeletal Muscle Regeneration	23
Applications of Chitosan and its Derivatives in the Treatment of Osteoarthritis	23
NAD+ Metabolism and Mitochondrial Activity in the Aged Oocyte: Focus on the Effects of NAMPT Stimulation	23
Emerging Roles of Adaptive Immune Response in Alzheimer's Disease	22
Stem Cell-derived Exosomal MicroRNA as Therapy for Vascular Age-related Diseases	22
Neuroprotective Effects of Celastrol in Neurodegenerative Diseases-Unscramble Its Major Mechanisms of Action and Targets	22
Potential of Neuroinflammation-Modulating Strategies in Tuberculous Meningitis: Targeting Microglia	22
Schizophrenia-Like Behaviors Arising from Dysregulated Proline Metabolism Are Associated with Altered Neuronal Morphology and Function in Mice with Hippocampal PRODH Deficiency	22
Irisin: A Potentially Fresh Insight into the Molecular Mechanisms Underlying Vascular Aging	22
Minocycline Administration Does Not Have an Effect on Retinal Ganglion Cell Survival in a Murine Model of Ocular Hypertension	22
Mechanistic Insights and Emerging Therapeutic Targets of Alzheimer's Disease: From the Perspective of Inter-Organ Crosstalk	22
Biomarkers of Parkinson’s Disease: From Basic Research to Clinical Practice	21
DNA Methylation Modulates Aging Process in Adipocytes	21
Spatiotemperal Dynamics of Osteoarthritis: Bridging Insights from Bench to Bedside	20
Role of Forkhead Box Protein O1 (FoxO1) in Stroke: A Literature Review	20
Senescent T Cells in Age-Related Diseases	20
Animal Models of Epilepsy: A Phenotype-oriented Review	19
Cerebral Glucose Metabolism and Potential Effects on Endoplasmic Reticulum Stress in Stroke	19
Intrinsic Capacity in Older Adults: Recent Advances	19
Acute Sarcopenia after Elective and Emergency Surgery	19

Long-Term Improvement in Hippocampal-Dependent Learning Ability in Healthy, Aged Individuals Following High Intensity Interval Training	19
Targeting Mitochondrial Sirtuins in Age-Related Neurodegenerative Diseases and Fibrosis	18
Astrocyte-Derived Extracellular Vesicles for Ischemic Stroke: Therapeutic Potential and Prospective	18
Brain-Derived Neurotrophic Factor Val66Met is Associated with Variation in Cortical Structure in Healthy Aging Subjects	18
Metformin Treatment Leads to Increased HIV Transcription and Gene Expression through Increased CREB Phosphorylation and Recruitment to the HIV LTR Promoter	18
Aberrantly High FBXO31 Impairs Oocyte Quality in Premature Ovarian Insufficiency	18
Time and Tissue Windows in Futile Reperfusion after Ischemic Stroke	18
Conceptual Overview of Biological Age Estimation	17
Probiotic Limosilactobacillus Reuteri (Lactobacillus Reuteri) Extends the Lifespan of Drosophila Melanogaster through Insulin/IGF-1 Signaling	17
Brain Mitochondrial Dysfunction: A Possible Mechanism Links Early Life Anxiety to Alzheimer’s Disease in Later Life	17
The Emerging Role of the Mitochondrial Respiratory Chain in Skeletal Aging	17
Investigating Causality and Shared Genetic Architecture between Neurodegenerative Disorders and Inflammatory Bowel Disease	17
The Metabolic Landscape in Osteoarthritis	17
Activated or Impaired: An Overview of DNA Repair in Neurodegenerative Diseases	17
The Role of Liquid-Liquid Phase Separation in the Accumulation of Pathological Proteins: New Perspectives on the Mechanism of Neurodegenerative Diseases	17
Effects of Ketogenic Diet on Neuroinflammation in Neurodegenerative Diseases	16
Bone Regeneration Enhanced by Quercetin-Capped Selenium Nanoparticles via miR206/Connexin43, WNT, and BMP signaling pathways	16
	16
Identification of Cathepsin B as a Therapeutic Target for Ferroptosis of Macrophage after Spinal Cord Injury	16
Molecular Mechanisms of Phase Separation and Amyloidosis of ALS/FTD-linked FUS and TDP-43	16
Ovariectomy and High Fat-Sugar-Salt Diet Induced Alzheimer's Disease/Vascular Dementia Features in Mice	16
Intestinal Permeability, Dysbiosis, Inflammation and Enteric Glia Cells: The Intestinal Etiology of Parkinson’s Disease	16
Oligomeric β-Amyloid Suppresses Hippocampal γ-Oscillations through Activation of the mTOR/S6K1 Pathway	16
Association Between Dementia and Optical Coherence Tomography Scan Quality	16
Alpha-Glucosidase Inhibitors in Aging and Aging-Related Diseases: Clinical Applications and Relevant Mechanisms	15
Establishing Predictors of Acute Sarcopenia: A Proof-Of-Concept Study Utilising Network Analysis	15
The Greater Omentum: Multifaceted Interactions in Neurological Recovery and Disease Progression	15
Advancing Neurological Health: Insights into Aging, Immunity, and Vascular Dynamics	15
Mind the Metabolic Gap: Bridging Migraine and Alzheimer's disease through Brain Insulin Resistance	15
Redefinition of Synovial Fibroblasts in Rheumatoid Arthritis	15
Gut Microbiota is an Impact Factor based on the Brain-Gut Axis to Alzheimer’s Disease: A Systematic Review	14
Mitochondria: A Potential Rejuvenation Tool against Aging	14
Brain Insulin Signaling is Associated with Late-Life Cognitive Decline	14
CAG Repeat Expansions Increase N1-Methyladenine to Alter TDP-43 Phase Separation: Lights Up Therapeutic Intervention for Neurodegeneration	14
CNTN1 Aggravates Neuroinflammation and Triggers Cognitive Deficits in Male Mice by Boosting Crosstalk between Microglia and Astrocytes	14
COVID-19 Pandemic and Osteoporosis in Elderly Patients	14
Alzheimer Disease: Recent Updates on Apolipoprotein E and Gut Microbiome Mediation of Oxidative Stress, and Prospective Interventional Agents	14
The Effects of Physical Running on Dendritic Spines and Amyloid-beta Pathology in 3xTg-AD Male Mice	14
Aging Intensifies Myeloperoxidase Activity after Ischemic Stroke	13
Disulfidptosis, A Novel Cell Death Pathway: Molecular Landscape and Therapeutic Implications	13
Missing Puzzle Pieces in Dementia Research: HCN Channels and Theta Oscillations	13
Inhibiting Glutaminase Exerts Opposite Effects on Ovariectomy-Induced and Age-Related Reductions in Murine Bone Mass	13
Inhibiting MicroRNA-141-3p Improves Musculoskeletal Health in Aged Mice	13
Atherosclerosis: The Involvement of Immunity, Cytokines and Cells in Pathogenesis, and Potential Novel Therapeutics	13
Shock Resuscitation - the Necessity and Priority of Renal Blood Perfusion Assessment	13
Are Older People Really More Susceptible to SARS-CoV-2?	13
Interconnected Pathways of Alzheimer's Disease and Osteoporosis: A Review of Genetic, Hormonal, and Environmental Influences	13
Aging Gut Microbiome in Healthy and Unhealthy Aging	13
Pros and Cons of Human Brain Organoids to Study Alzheimer’s Disease	13
Neuronal Senescence in the Aged Brain	13
Melatonin and Prostate Cancer: Anti-tumor Roles and Therapeutic Application	13
Deep Learning Based on Computed Tomography Predicts Response to Chemoimmunotherapy in Lung Squamous Cell Carcinoma	13
Shedding Light on the Interaction Between Rif1 and Telomeres in Ovarian Cancer	13
Plasma Neurodegenerative Biomarkers in Cognitively Preserved Nonagenarians	13
Revolutionizing Senescence Detection: Advancements from Traditional Methods to Cutting-Edge Techniques	13
Responsiveness to Tocilizumab in Anti-Acetylcholine Receptor-Positive Generalized Myasthenia Gravis	12
Longevity-Associated Transcription Factor ATF7 Promotes Healthspan by Suppressing Cellular Senescence and Systematic Inflammation	12
Melatonin as an Antioxidant Agent in Stroke: An Updated Review	12
Changes in Plasma Neutral and Ether-Linked Lipids Are Associated with The Pathology and Progression of Alzheimer’s Disease	12
cGAS-STING Pathway Performance in the Vulnerable Atherosclerotic Plaque	12
Osteoporosis in Relation to a Bone-Related Aging Biomarker Derived from the Urinary Proteomic Profile: A Population Study	12
Irreversibility of Pulmonary Fibrosis	12
Age-Related Hormones Changes and Its Impact on Health Status and Lifespan	11
Crosstalk between Circadian Rhythm Dysregulation and Tumorigenesis, Tumor Metabolism and Tumor Immune Response	11
Genetic Risk, Inflammation, and Therapeutics: An Editorial Overview of Recent Advances in Aging Brains and Neurodegeneration	11
Cerebral Small Vessel Disease: Current and Emerging Therapeutic Strategies	11
Targeting the Hepatic Microenvironment to Improve Ischemia/Reperfusion Injury: New Insights into the Immune and Metabolic Compartments	11
A Potential “Anti-Warburg Effect” in Circulating Tumor Cell-mediated Metastatic Progression?	11
A longitudinal Analysis of the Association between Socioeconomic Position and Multimorbidity in the European Prospective Investigation into Cancer and Nutrition Study	11
Immunometabolism In Brain Aging and Neurodegeneration: Bridging Metabolic Pathways and Immune Responses	11
Hypoxic Preconditioning Mitigates Acute Hypoxia Induced MS/VDB Cholinergic Cell Loss and Memory Impairments	11
Sirtuins at the Crossroads between Mitochondrial Quality Control and Neurodegenerative Diseases: Structure, Regulation, Modifications, and Modulators	11
Age and Sex Affect Essential Tremor (ET) Plus: Clinical Heterogeneity in ET Based on the National Survey in China	11
Role and Mechanism of Epigenetic Regulation in the Aging of Germ Cells: Prospects for Targeted Interventions	10
Circadian Rhythm and the Risk of Cardiovascular Diseases: Genetic Evidence	10
USP7 Inhibits Osteoclastogenesis via Dual Effects of Attenuating TRAF6/TAK1 Axis and Stimulating STING Signaling	10
Neuroserpin and Extracellular Vesicles in Ischemic Stroke: Partners in Neuroprotection?	10
Apolipoprotein ε in Brain and Retinal Neurodegenerative Diseases	10
Profile for Brain Disease Research Infrastructure for Data Gathering and Exploration (BRIDGE) Platform	10
Clinical Characteristics, Transmissibility, Pathogenicity, Susceptible Populations, and Re-infectivity of Prominent COVID-19 Variants	10

Traveling Subject-Informed Harmonization Increases Reliability of Brain Diffusion Tensor and Neurite Mapping	10
Sarcopenic Obesity: An Emerging Public Health Problem, But an Answer Appears to Be Available	10
Metabolic Dysfunction in Idiopathic Intracranial Hypertension: Current Theories and Updates	10
Bidirectional Crosstalk between the Heart and Brain in Alzheimer's Disease	10
Metformin's Mechanisms in Attenuating Hallmarks of Aging and Age-Related Disease	9
Differential Effects of Endurance Exercise on Musculoskeletal and Hematopoietic Modulation in Old Mice	9
Underlying Mechanisms and Treatment of Cellular Senescence-Induced Biological Barrier Interruption and Related Diseases	9
Vascular Calcification in Chronic Kidney Disease: An Update and Perspective	9
The Role of Oxidative Stress in Multiple Exercise-Regulated Bone Homeostasis	9
Mesenchymal Stem Cell-Derived Exosomes Promote Recovery of The Facial Nerve Injury through Regulating Macrophage M1 and M2 Polarization by Targeting the P38 MAPK/NF-Κb Pathway	9
Predictive Value of Plasma Neurofilament Light Chain for Neurological Outcomes in Patients with Intracerebral Hemorrhage	9
YAP/TAZ as Molecular Targets in Skeletal Muscle Atrophy and Osteoporosis	9
Histone Deacetylase 3: A Potential Therapeutic Target for Atherosclerosis	9
Toward the Identification of Neurophysiological Biomarkers for Alzheimer’s Disease in Down Syndrome: A Potential Role for Cross-Frequency Phase-Amplitude Coupling Analysis	9
Mitochondrial Transfer in the Neurovascular Unit, Not Only for Energy Rescue: A Systematic Review	8
Diagnostic and Therapeutic Potential of Photo-Responsive Nanomaterials in Osteoarthritis	8
Endothelial Senescence in Neurological Diseases	8
P-Glycoprotein Aggravates Blood Brain Barrier Dysfunction in Experimental Ischemic Stroke by Inhibiting Endothelial Autophagy	8
COVID-19 and Cardiovascular Diseases: From Cellular Mechanisms to Clinical Manifestations	8
NeuroD1 Regulated Endothelial Gene Expression to Modulate Transduction of AAV-PHP.eB and Recovery Progress after Ischemic Stroke	8
Ongoing Clinical Trials in Aging-Related Tissue Fibrosis and New Findings Related to AhR Pathways	8
Decoding Microglial Polarization and Metabolic Reprogramming in Neurodegenerative Diseases: Implications for Disease Progression and Therapy	8
SARS-CoV-2 S Protein Reduces Cytoprotective Defenses and Promotes Human Endothelial Cell Senescence	8
Scientific Advancements in Drug Development and Trials for Urothelial Carcinoma: Insights From the 2023 ASCO-GU Cancers Symposium	8
HIV Nef Expression Down-modulated GFAP Expression and Altered Glutamate Uptake and Release and Proliferation in Astrocytes	8
Will New Variants Emerge after Delta and Omicron?	8
CD16-CD56bright NK Cells: A Protective NK Cell Subset for Progression and Prognosis in Amyotrophic Lateral Sclerosis	8
Overexpression of RACGAP1 by E2F1 Promotes Neuroendocrine Differentiation of Prostate Cancer by Stabilizing EZH2 Expression	8
A Framework for an Effective Healthy Longevity Clinic	8
Autophagy and Diabetic Encephalopathy: Mechanistic Insights and Potential Therapeutic Implications	8
Cell Heterogeneity Uncovered by Single-Cell RNA Sequencing Offers Potential Therapeutic Targets for Ischemic Stroke	7
The Organ-Joint Axes in Osteoarthritis: Significant Pathogenesis and Therapeutic Targets	7
Myelin Changes in Poor Sleepers: Insights into Glymphatic Clearance Function and Regional Circadian Clock Gene Expression	7
Senescent Macrophages and the Lung Cancer Microenvironment: A New Perspective on Tumor Immune Evasion	7
Aging Deteriorates Blood Brain Barrier Function and Polarizes Adaptive T Cell Expansion Contributing to Neurocognitive Damage in Experimental Cirrhosis	7
Chondroitin Sulfate Proteoglycans Revisited: Its Mechanism of Generation and Action for Spinal Cord Injury	7
Hallmarks of Skin Aging: Update	7
Hypoxic Conditioning: A Potential Perioperative Strategy to Reduce Abdominal Aortic Occlusion-Related Injury in Mouse Proximal and Distal Organs	7
ARID1a Gene as a Potential Early Marker to Tackle Endometriosis-Associated Ovarian Cancer	7
ROS-Induced Endothelial Dysfunction in the Pathogenesis of Atherosclerosis	7
Gut Microbiota and Its Metabolites: The Emerging Bridge Between Coronary Artery Disease and Anxiety and Depression?	7
From Insight to Eyesight: Unveiling the Secrets of the Insulin-Like Growth Factor Axis in Retinal Health	7
Aging, Cellular Senescence, and Glaucoma	7
Alzheimer Disease Pathology and Neurodegeneration in Midlife Obesity: A Pilot Study	6
Absence of TSC1 Accelerates CD8+ T cell-mediated Acute Cardiac Allograft Rejection	6
The Role and Mechanism of Vascular Aging in Geriatric Vascular Diseases	6
Lactylation: An Innovative Approach to Disease Control	6
The Neglected Sibling: NLRP2 Inflammasome in the Nervous System	6
The Double-Edged Effects of Substance P in the Pathology of Alzheimer’s Disease	6
Drug Screening and Validation Targeting TDP-43 Proteinopathy for Amyotrophic Lateral Sclerosis	6
Senolytic Treatment Improve Small Intestine Regeneration in Aging	6
Immunosenescence in Sepsis: Molecular Mechanisms and Potential Therapeutic Targets	6
Gender Differences Associated with Hyper-Inflammatory Conditions in COVID-19 Patients	6
Prediction Models for Osteoporotic Fractures Risk: A Systematic Review and Critical Appraisal	6
Adiponectin mRNA Conjugated with Lipid Nanoparticles Specifically Targets the Pathogenesis of Type 2 Diabetes	6
Deformability of Heterogeneous Red Blood Cells in Aging and Related Pathologies	6
Biological Aging in Combination with Lifestyle Factors in the Blood-Based Methylome: A Biomarker for Colorectal Cancer Susceptibility in African American Women	6
Brain Iron Dyshomeostasis and Ferroptosis in Alzheimer’s Disease Pathophysiology: Two Faces of the Same Coin	6
The NRF2/ID2 Axis in Vascular Smooth Muscle Cells: Novel Insights into the Interplay between Vascular Calcification and Aging	6
Engineered Mitochondrial Transplantation as An Anti-Aging Therapy	6
Targeting Mitochondrial Integrity as a New Senolytic Strategy	6
Mesenchymal Stem Cell Senescence during Aging:From Mechanisms to Rejuvenation Strategies	6
BMF-AS1/BMF Promotes Diabetic Vascular Calcification and Aging both In Vitro and In Vivo	6
Role of Crosstalk between Glial Cells and Immune Cells in Blood-Brain Barrier Damage and Protection after Acute Ischemic Stroke	6
Expert consensus on Prospective Precision Diagnosis and Treatment Strategies for Osteoporotic Fractures	6
m6A Reader HNRNPC Facilitates Adipogenesis by Regulating Cytoskeletal Remodeling through Enhanced Lcp1 mRNA Stability	6
Rare Clinical Presentation of Postmenopausal Endometriosis: A New Perspective	6
Targeting Crosstalk of Signaling Pathways among Muscles-Bone-Adipose Tissue: A Promising Therapeutic Approach for Sarcopenia	6
The Cause of Alzheimer’s Disease: The Theory of Multipathology Convergence to Chronic Neuronal Stress	6
Upregulation of Na/H Exchanger in Astrogliosis and Early Alzheimer’s Disease Pathogenesis	5
Early Aβ42 Exposure Causes Learning Impairment in Later Life	5
Ischemic Stroke and the Biological Hallmarks of Aging	5
Targeting Estrogen Receptor Beta Ameliorates Diminished Ovarian Reserve via Suppression of the FOXO3a/Autophagy Pathway	5
A Combination Study of Pre- and Clinical Trial: Seaweed Consumption Reduces Aging-Associated Muscle Loss!	5
Cellular Senescence in Acute Liver Injury: What Happens to the Young Liver?	5
Skeletal Muscle Metabolic Alternation Develops Sarcopenia	5
Association of Inflammatory Mediators with Mitochondrial DNA Variants in Geriatric COVID-19 Patients	5
Unveiling the Therapeutic Promise of Epigenetics in Vascular Cognitive Impairment and Vascular Dementia	5
The Role of Myeloid-Derived Suppressor Cells in Multiple Sclerosis and Its Animal Model	5
Autophagy in Neuroinflammation: A Focus on Epigenetic Regulation	5
Brain Regulates Neuronal Activity Directly through the Heartbeat: A New Pathway of Heart-Brain Interaction	5
Loss of Pinch Proteins Causes Severe Degenerative Disc Disease-Like Lesions in Mice	5
Connecting the Dots: The Cerebral Lymphatic System as a Bridge Between the Central Nervous System and Peripheral System in Health and Disease	5
CD4+ CTLs Act as a Key Effector Population for Allograft Rejection of MSCs in a Donor MHC-II Dependent Manner in Injured Liver	5
Recent Neurotherapeutic Strategies to Promote Healthy Brain Aging: Are we there yet?	5
M2 Microglial Extracellular Vesicles Attenuated Blood-brain Barrier Disruption via MiR-23a-5p in Cerebral Ischemic Mice	5
The Interfascicular Matrix of Energy Storing Tendons Houses Heterogenous Cell Populations Disproportionately Affected by Aging	5
Mechanisms of the Mitochondrial Unfolded Protein Response in Caenorhabditis elegans and Mammals and Its Roles in Striated Muscles	5
X-box Binding Protein 1: An Adaptor in the Pathogenesis of Atherosclerosis	5
Lactic Acid Bacteria and Aging: Unraveling the Interplay for Healthy Longevity	5
Unraveling Homocysteine's Role in Dementia: No Specific Association with Alzheimer's Disease, but a Connection to White Matter Hyperintensities	5
Metabolic Rewiring and Post-Translational Modifications: Unlocking the Mechanisms of Bone Turnover in Osteoporosis	5
A Turning Point for China’s Population: No Child and Long Illness	4
Edge Density Imaging Identifies White Matter Biomarkers of Late-Life Obesity and Cognition	4
Mechanical Ventilation in COVID-19 Patients: a question from Age to Frailty	4