Cold Spring Harbor Perspectives in Medicine

Papers
(The TQCC of Cold Spring Harbor Perspectives in Medicine is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Developmental Oncology: Principles and Therapy of Cancers of Children and Young Adults558
iPSC-RPE in Retinal Degeneration: Recent Advancements and Future Perspectives349
Metabolic Signaling in Cancer157
Developing New Vectors for Retinal Gene Therapy62
Personalized Financial Planning Using Applied Genetics42
Monitoring the Cell Cycle of Tumor Cells in Mouse Models of Human Cancer36
Toward Retinal Organoids in High-Throughput36
Pathomechanisms of Inherited Retinal Degeneration and Perspectives for Neuroprotection35
Ovarian Clear Cell Carcinoma: An Endometriosis-Associated Cancer with Therapeutic Challenges32
How CRISPR Is Revolutionizing the Generation of New Models for Cancer Research27
Embryological Insights into the Origin of Epithelial Cancers of the Female Reproductive Tract26
Genetics and Epigenetics of Type 1 Diabetes Self-Reactive T Cells26
Clinical Immunologic Interventions for the Treatment of Type 1 Diabetes: Challenges, Choice, and Timing of Immunomodulators24
From the Inside Out: Exposing the Roles of Urea Cycle Enzymes in Tumors and Their Micro and Macro Environments22
Inflammatory β-Cell Stress and Immune Surveillance in Type 1 Diabetes20
Mechanisms of Organ-Specific Metastasis of Breast Cancer19
α-Synuclein in Parkinson's Disease: 12 Years Later19
Retinal Disorders18
Functional Neuroanatomy of the Normal and Pathological Basal Ganglia17
Therapeutic Gene Editing in Inherited Retinal Disorders17
Optogenetic Vision Restoration16
Preclinical Models for the Study of Lung Cancer Pathogenesis and Therapy Development16
Aging and Inflammation15
Immunology of Retinitis Pigmentosa and Gene Therapy–Associated Uveitis15
Autophagy and Protein Quality Control in Parkinson's Disease14
Endothelial Cell Differentiation and Hemogenic Specification13
Innate Immunity in Type 1 Diabetes13
Breast Cancer Immunity: It is TIME for the Next Chapter12
Evolutionary Approaches in Aging Research12
The Pathogenesis of Type 1 Diabetes12
Lipid Alterations and Pathogenic Roles in Synucleinopathies11
Epitope Hierarchy in Type 1 Diabetes Pathogenesis11
Acute Promyelocytic Leukemia, Retinoic Acid, and Arsenic: A Tale of Dualities11
From Life Span to Health Span: Declaring “Victory” in the Pursuit of Human Longevity11
The Funding Channels of Geroscience11
Early Detection of Ovarian Cancer10
Toward a Unified Theory of Why Young People Develop Cancer10
The Human Pancreas in Type 1 Diabetes: Lessons Learned from the Network of Pancreatic Organ Donors with Diabetes10
Germline Genetic Testing for Hereditary Breast and Ovarian Cancer: Current Concepts in Risk Evaluation10
Lessons Learned from the Development of the First FDA-Approved Gene Therapy Drug, Voretigene Neparvovec-rzyl10
Lymphatic Tissue and Organ Engineering for In Vitro Modeling and In Vivo Regeneration10
T Cell Differentiation in Autoimmune Type 1 Diabetes9
Beyond Static Pipes: Mechanisms and In Vitro Models of Vascular Aging9
Comparison of Worldwide Disease Prevalence and Genetic Prevalence of Inherited Retinal Diseases and Variant Interpretation Considerations9
Modeling Brain Vasculature Immune Interactions In Vitro9
A History of Biosafety: U.S. Perspective9
Endothelial Lipid Metabolism9
Wnt/frizzled Signaling in Endothelium: A Major Player in Blood-Retinal- and Blood-Brain-Barrier Integrity9
Understanding the Warburg Effect in Cancer8
New Paradigms in the Clinical Management of Li–Fraumeni Syndrome8
Technologies for Decoding Cancer Metabolism with Spatial Resolution8
Dormancy in Breast Cancer8
Emerging Therapies for Breast Cancer8
The Power and Promise of Patient-Derived Xenografts of Human Breast Cancer8
Notch Signaling in Vascular Endothelial and Mural Cell Communications8
Next-Generation Modeling of Cancer Using Organoids8
Mechanics of Lymphatic Pumping and Lymphatic Function7
Historical Perspectives of Parkinson's Disease: Early Clinical Descriptions and Neurological Therapies7
Leucine-Rich Repeat Kinase 2: Pathways to Parkinson's Disease7
Parallels in Canonical Developmental Signaling Pathways between Normal Development and the Tumor Microenvironment7
History of Finding Genes and Mutations Causing Inherited Retinal Diseases7
The Extraordinary Phenotypic and Genetic Variability of Retinal and Macular Degenerations: The Relevance to Therapeutic Developments7
Retinal Degeneration Animal Models in Bardet–Biedl Syndrome and Related Ciliopathies7
Cellular Origins and Lineage Plasticity in Cancer7
Osteosarcoma through the Lens of Bone Development, Signaling, and Microenvironment7
Rare Epithelial Ovarian Cancers: Low Grade Serous and Mucinous Carcinomas7
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