OOIR: Observatory of International Research

Papers

(The median citation count of Oncogenesis is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Noncanonical PRC1.1 targets BTG2 to retain cyclin gene expression and cell growth in neuroblastoma	238
GPX3 suppresses gallbladder cancer progression by modulating redox balance, glycolysis, and anti-tumor immunity	158
PELI1 and EGFR cooperate to promote breast cancer metastasis	88
C1s protects cutaneous squamous carcinoma cells from TRAIL-induced apoptosis	83
Discovery of neddylation E2s inhibitors with therapeutic activity	80
USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c	70
NUCKS1 promotes invasion and metastasis of colorectal cancer by stabilizing HDAC2 and activating AKT	68
Gemcitabine as chemotherapy of head and neck cancer in Fanconi anemia patients	55
Vortioxetine hydrobromide inhibits the growth of gastric cancer cells in vivo and in vitro by targeting JAK2 and SRC	50
P4HB maintains Wnt-dependent stemness in glioblastoma stem cells as a precision therapeutic target and serum marker	32
A HOTAIR-associated super-enhancer orchestrates glioblastoma malignancy via MEST	32
Correction: Overexpression of SMC4 activates TGFβ/Smad signaling and promotes aggressive phenotype in glioma cells	32
Targeted metabolomics detects a putatively diagnostic signature in plasma and dried blood spots from head and neck paraganglioma patients	30
Sphingosine 1-phosphate signalling in cancer stem cells	28
Spindle function and Wnt pathway inhibition by PBX1 to suppress tumor progression via downregulating DCDC2 in colorectal cancer	25
Biological differences underlying sex and gender disparities in bladder cancer: current synopsis and future directions	25
UHRF1 overexpression promotes osteosarcoma metastasis through altered exosome production and AMPK/SEMA3E suppression	24
Calreticulin enhances gastric cancer metastasis by dimethylating H3K9 in the E-cadherin promoter region mediating by G9a	24
Ablation of sphingosine kinase 2 suppresses fatty liver-associated hepatocellular carcinoma via downregulation of ceramide transfer protein	24
Correction: Mitochondrial dysfunction and impaired growth of glioblastoma cell lines caused by antimicrobial agents inducing ferroptosis under glucose starvation	23
USP35 promotes cell proliferation and chemotherapeutic resistance through stabilizing FUCA1 in colorectal cancer	23
PLEKHA4 is transcriptionally regulated by HOXD9 and regulates glycolytic reprogramming and progression in glioblastoma via activation of the STAT3/SOCS-1 pathway	21
Exosomes and cancer - Diagnostic and prognostic biomarkers and therapeutic vehicle	21
Coordinate transcriptional regulation of ErbB2/3 by C-terminal binding protein 2 signals sensitivity to ErbB2 inhibition in pancreatic adenocarcinoma	19
Collagen type IV alpha 6 promotes tumor progression and chemoresistance in ovarian cancer by activating the discoidin domain receptor 1 pathway	19

STAG2 expression imparts distinct therapeutic vulnerabilities in muscle-invasive bladder cancer cells	19
Involvement of the pro-oncogenic enzyme fatty acid synthase in the hallmarks of cancer: a promising target in anti-cancer therapies	19
Diltiazem inhibits breast cancer metastasis via mediating growth differentiation factor 15 and epithelial-mesenchymal transition	18
Preneoplastic cells switch to Warburg metabolism from their inception exposing multiple vulnerabilities for targeted elimination	17
NAC1 transcriptional activation of LDHA induces hepatitis B virus immune evasion leading to cirrhosis and hepatocellular carcinoma development	17
An E3 ligase TRIM1 promotes colorectal cancer progression via K63-linked ubiquitination and activation of HIF1α	17
PFKFB4 interacts with FBXO28 to promote HIF-1α signaling in glioblastoma	17
FLT4 activation promotes acute lymphoid leukemia survival through stabilization of MDM2/MDMX and inactivation of p53	17
Analysis of the metabolic proteome of lung adenocarcinomas by reverse-phase protein arrays (RPPA) emphasizes mitochondria as targets for therapy	16
WDR5 facilitates recruitment of N-MYC to conserved WDR5 gene targets in neuroblastoma cell lines	16
Transgelin promotes lung cancer progression via activation of cancer-associated fibroblasts with enhanced IL-6 release	16
NFATc1-mediated activation of the pentose phosphate pathway and cell cycle dysregulation collectively drive tumor progression	16
Anti-PD-1 therapy achieves favorable outcomes in HBV-positive non-liver cancer	16
Comprehensive multi-omics analysis of breast cancer reveals distinct long-term prognostic subtypes	15
HLTF promotes hepatocellular carcinoma progression by enhancing SRSF1 stability and activating ERK/MAPK pathway	15
TGF-β signaling redirects Sox11 gene regulatory activity to promote partial EMT and collective invasion of oncogenically transformed intestinal organoids	15
Involvement of Kindlin-1 in cutaneous squamous cell carcinoma	15
Generating in vitro models of NTRK-fusion mesenchymal neoplasia as tools for investigating kinase oncogenic activation and response to targeted therapy	15
Targeting macrophage migration inhibitory factor as a potential therapeutic strategy in colorectal cancer	15
SLC26A3/NHERF2-IκB/NFκB/p65 feedback loop suppresses tumorigenesis and metastasis in colorectal cancer	15
Subtype-specific role for Jagged1 in promoting or inhibiting breast tumor formation	15
ACT001 inhibited CD133 transcription by targeting and inducing Olig2 ubiquitination degradation	15
Correction: PBK phosphorylates MSL1 to elicit epigenetic modulation of CD276 in nasopharyngeal carcinoma	14
Correction: Non-enzymatic heparanase enhances gastric tumor proliferation via TFEB-dependent autophagy	14
Correction: Oncogenic PI3K/AKT promotes the step-wise evolution of combination BRAF/MEK inhibitor resistance in melanoma	14
LUBAC promotes angiogenesis and lung tumorigenesis by ubiquitinating and antagonizing autophagic degradation of HIF1α	14
WDR4 promotes the progression and lymphatic metastasis of bladder cancer via transcriptional down-regulation of ARRB2	14
Correction: Targeting IL-3Rα on tumor-derived endothelial cells blunts metastatic spread of triple-negative breast cancer via extracellular vesicle reprogramming	14
Aberrant APOBEC3C expression induces characteristic genomic instability in pancreatic ductal adenocarcinoma	14
Correction: TRIM11 facilitates chemoresistance in nasopharyngeal carcinoma by activating the β-catenin/ABCC9 axis via p62-selective autophagic degradation of Daple	13
Identification of pancreatic cancer-specific protease substrates for protease-dependent targeted delivery	13
The role of histone demethylase PHF2 as a tumour suppressor in hepatocellular carcinoma by regulating SRXN1	13
CD147-high extracellular vesicles promote gastric cancer metastasis via VEGF/AKT/eNOS and AKT/mTOR pathways	13
CD9, a tetraspanin in cancer: biology and therapeutic promise in acute leukemia	13
The impact of neoadjuvant chemotherapy on the tumor microenvironment in advanced high-grade serous carcinoma	12
Retraction Note: A natural food sweetener with anti-pancreatic cancer properties	12
Progesterone receptor potentiates macropinocytosis through CDC42 in pancreatic ductal adenocarcinoma	12
Targeting fucosyltransferase FUT8 as a prospective therapeutic approach for DLBCL	11
The p52-ZER6/G6PD axis alters aerobic glycolysis and promotes tumor progression by activating the pentose phosphate pathway	11
TFCP2L1 drives stemness and enhances their resistance to Sorafenib treatment by modulating the NANOG/STAT3 pathway in hepatocellular carcinoma	11
IFFO1 inhibits breast cancer by coordinating mitochondrial fission and fatty acid synthesis via the LaminA/C-PGC1α axis	11
A dominant SRCAP truncating mutation promotes squamous cell carcinoma progression	11
Condensate remodeling reorganizes innate SS18 in synovial sarcomagenesis	11
The SWI/SNF ATPase BRG1 facilitates multiple pro-tumorigenic gene expression programs in SMARCB1-deficient cancer cells	11
Transcriptomic analysis identifies B-lymphocyte kinase as a therapeutic target for desmoplastic small round cell tumor cancer stem cell-like cells	11
Tumor suppressor BAP1 suppresses disulfidptosis through the regulation of SLC7A11 and NADPH levels	10
Fatty acid uptake mediated by FABP4 promotes the formation of CD8+T cell senescence through lipid peroxidation in the adipocyte-rich microenvironment of Ovarian Cancer	10
Methylation of HBP1 by PRMT1 promotes tumor progression by regulating actin cytoskeleton remodeling	10
Paladin, overexpressed in colon cancer, is required for actin polymerisation and liver metastasis dissemination	10
Negligible role of TRAIL death receptors in cell death upon endoplasmic reticulum stress in B-cell malignancies	10

Dual role of ANGPTL8 in promoting tumor cell proliferation and immune escape during hepatocarcinogenesis	10
Correction: FAM83B inhibits ovarian cancer cisplatin resistance through inhibiting Wnt pathway	9
Lipids in cancer: a global view of the contribution of lipid pathways to metastatic formation and treatment resistance	9
Androgen receptor variant 7 exacerbates hepatocarcinogenesis in a c-MYC-driven mouse HCC model	9
Proteomic meta-analysis unveils new frontiers for biomarkers research in pancreatic carcinoma	9
Rab37-mediated OPN secretion enriches SPP1+ macrophages through autocrine–paracrine signaling to drive lung tumor progression	9
Retraction Note: Platelet-derived growth factor receptor-α and -β promote cancer stem cell phenotypes in sarcomas	9
Correction: USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c	8
Heparanase modulates the prognosis and development of BRAF V600E-mutant colorectal cancer by regulating AKT/p27Kip1/Cyclin E2 pathway	8
Correction: FIBP knockdown attenuates growth and enhances chemotherapy in colorectal cancer via regulating GSK3β-related pathways	8
RIOK3 sustains colorectal cancer cell survival under glucose deprivation via an HSP90α-dependent pathway	8
Acidovorax temperans skews neutrophil maturation and polarizes Th17 cells to promote lung adenocarcinoma development	8
MYCN induces cell-specific tumorigenic growth in RB1-proficient human retinal organoid and chicken retina models of retinoblastoma	8
LIN28B inhibition sensitizes cells to p53-restoring PPI therapy through unleashed translational suppression	8
CDK4/6 inhibitors and the pRB-E2F1 axis suppress PVR and PD-L1 expression in triple-negative breast cancer	8
Chasing non-existent “microRNAs” in cancer	8
CENPF (+) cancer cells promote malignant progression of early-stage TP53 mutant lung adenocarcinoma	8
Designing patient-oriented combination therapies for acute myeloid leukemia based on efficacy/toxicity integration and bipartite network modeling	8
miR-137–LAPTM4B regulates cytoskeleton organization and cancer metastasis via the RhoA-LIMK-Cofilin pathway in osteosarcoma	8
Inhibition of LDHB triggers DNA damage and increases cisplatin sensitivity in pleural mesothelioma	7
ACSL6 modulates docosahexaenoic acid-induced cytotoxicity to potentiate chemotherapy response in colorectal and breast cancer	7
Heterozygotic Brca1 mutation initiates mouse genome instability at embryonic stage	7
LPA receptor 1 (LPAR1) is a novel interaction partner of Filamin A that promotes Filamin A phosphorylation, MRTF-A transcriptional activity and oncogene-induced senescence	7
Programmed cell death 11 modulates but not entirely relies on p53-HDM2 loop to facilitate G2/M transition in colorectal cancer cells	7
Retinoic acid receptor β modulates mechanosensing and invasion in pancreatic cancer cells via myosin light chain 2	7
Targeting pregnane X receptor with a potent agonist-based PROTAC to delay colon cancer relapse	7
Investigation of lncRNA expression in newly diagnosed multiple myeloma reveals a LINC01432-CELF2 axis as an inhibitor of apoptosis	7
DDX3X interacts with SIRT7 to promote PD-L1 expression to facilitate PDAC progression	6
A MYC-ZNF148-ID1/3 regulatory axis modulating cancer stem cell traits in aggressive breast cancer	6
Deep learning identifies a T-cell exhaustion-dependent transcriptional signature for predicting clinical outcomes and response to immune checkpoint blockade	6
Correction: LXRα limits TGFβ-dependent hepatocellular carcinoma associated fibroblast differentiation	6
Myeloma mesenchymal stem cells’ bioenergetics afford a novel selective therapeutic target	6
Stabilization of FASN by USP5-mediated deubiquitination promotes hepatocellular carcinoma progression	6
Glucocorticoid receptor-induced non-muscle caldesmon regulates metastasis in castration-resistant prostate cancer	6
The SUMO protease SENP1 promotes aggressive behaviors of high HIF2α expressing renal cell carcinoma cells	6
Metastasis suppressing properties of the cell-surface anchored serine protease prostasin: new functional and mechanistic insights from breast cancer	6
Mitochondrial dysfunction and impaired growth of glioblastoma cell lines caused by antimicrobial agents inducing ferroptosis under glucose starvation	6
Exploring potential molecular resistance and clonal evolution in advanced HER2-positive gastric cancer under trastuzumab therapy	6
ONC201 enhances the cytotoxic effect of cisplatin through ATF3/ATF4/CHOP in head and neck squamous cell carcinoma cells	6
Tumor suppressor p53 restrains cancer cell dissemination by modulating mitochondrial dynamics	6
Chemotherapy-induced executioner caspase activation increases breast cancer malignancy through epigenetic de-repression of CDH12	6