OOIR: Observatory of International Research

Papers

(The H4-Index of ACS Synthetic Biology is 39. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
LOICA: Integrating Models with Data for Genetic Network Design Automation	85
DisGUVery: A Versatile Open-Source Software for High-Throughput Image Analysis of Giant Unilamellar Vesicles	83
Stem Loop Mediated Transgene Modulation in Human T Cells	80
Discovering Content through Text Mining for a Synthetic Biology Knowledge System	79
Bacteria Engineered to Produce Serotonin Modulate Host Intestinal Physiology	76
Mobile Translation Systems Generate Genomically Engineered Escherichia coli Cells with Improved Growth Phenotypes	75
Preventing Production Escape Using an Engineered Glucose-Inducible Genetic Circuit	69
Simplified Construction of Engineered Bacillus subtilis Host for Improved Expression of Proteins Harboring Noncanonical Amino Acids	66
Efficient Mutasynthesis of “Non-Natural” Antitubercular Ilamycins with Low Cytotoxicity	61
The Japan-UK Synthetic Biology Conference, Spring 2025: Strengthening Global Links to Engineer Biology	61
Synthetic Biology 2.0: The Dawn of a New Era	60
Cell-Free Expression of Soluble Leafhopper Proteins from Brochosomes	58
Development of a Recombineering System for the Acetogen Eubacterium limosum with Cas9 Counterselection for Markerless Genome Engineering	56
Nano-Regulation of Gene Expression in Chlamydomonas reinhardtii: Harnessing AuNPs for Remotely Switchable Lipid Biosynthesis via Antisense Oligonucleotides	53
Hybrid Methylotrophic Pathway in Serratia marcescens for Sustainable Terpenoid Biosynthesis	53
Energy Aware Technology Mapping of Genetic Logic Circuits	53
Synthetic Biology Design as a Paradigm Shift toward Manufacturing Affordable Adeno-Associated Virus Gene Therapies	52
Engineered Mutants of a Marine Photosynthetic Purple Nonsulfur Bacterium with Increased Volumetric Productivity of Polyhydroxyalkanoate Bioplastics	52
Engineering Cyanobacterial Cell Factories for Photosynthetic Production of Fructose	50
Engineered l-Lactate Responding Promoter System Operating in Glucose-Rich and Anoxic Environments	49
LevSeq: Rapid Generation of Sequence-Function Data for Directed Evolution and Machine Learning	49
An Autocatalytic Peptide Cyclase Improves Fidelity and Yield of Circular Peptides In Vivo and In Vitro	48
Actomyosin-Driven Division of a Synthetic Cell	47
Protease-Responsive Toolkit for Conditional Targeted Protein Degradation	46
Combining Chemical Catalysis with Enzymatic Steps for the Synthesis of the Artemisinin Precursor Dihydroartemisinic Acid	46

Engineering a Novel Acetyl-CoA Pathway for Efficient Biosynthesis of Acetyl-CoA-Derived Compounds	46
In VivoSampling of Intracellular Heterogeneity ofPseudomonas putidaEnables Multiobjective Optimization of Genetic Devices	45
Predicting and Interpreting Protein Developability Via Transfer of Convolutional Sequence Representation	45
Construction of an Engineered Escherichia coli with Efficient Chemotactic and Metabolizing Ability toward Tetrathionate	45
Targeting Transcriptional and Translational Hindrances in a Modular T7RNAP Expression System in Engineered Pseudomonas putida	44
Cell Free Bacteriophage Synthesis from Engineered Strains Improves Yield	43
IWBDA 2022: Toward a Modular Future of Synthetic Biology Driven by Bio-Design Automation	43
Control of λ Lysogenic Escherichia coli Cells by Synthetic λ Phage Carrying cI^antisense	42
Engineering Tissue-Scale Properties with Synthetic Cells: Forging One from Many	42
A Photoresponsive Homing Endonuclease for Programmed DNA Cleavage	41
Optimal LentiCRISPR-Based System for Sequential CRISPR/Cas9 Screens	41
Cell-Free Protein Synthesis as a Method to Rapidly Screen Machine Learning-Generated Protease Variants	40
Metabolic Engineering of Clostridium tyrobutyricum for High-Yield n-Butanol Production by Increasing Intracellular Reducing Equivalent with NADPH-Dependent 3-Hydroxybutyryl-CoA Dehydroge	40
Highly Accurate Sequence- and Position-Independent Error Profiling of DNA Synthesis and Sequencing	39
Maximizing Heterologous Expression of Engineered Type I Polyketide Synthases: Investigating Codon Optimization Strategies	39