OOIR: Observatory of International Research

Papers

(The median citation count of Advances in Wound Care is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Efficacy and Safety of Lidocaine Patch in the Management of Acute Postoperative Wound Pain: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Trials	328
Development of a Tissue Oxygenation Flow-Based Index Toward Discerning the Healing Status in Diabetic Foot Ulcers	123
Efficacy of D33 Sealed Foam in Preventing Skin Injury from Surgical Positioning: Randomized Clinical Trial	92
Diagnostic Performance of Ultrasonography for Diabetic Foot Osteomyelitis	92
Standardized Wound Care: Patchwork Practices?	75
Dynamic Prediction of Time to Wound Healing at Routine Wound Care Visits	66
Vasoconstrictor Agent Administration as a Risk Factor for Pressure Injury Development in Intensive Care Unit Patients: A Systematic Review and Meta-Analysis	48
Wound Healing Driver Gene and Therapeutic Development: Political and Scientific Hurdles	45
Pressure Injury Incidence and Quality of Care Index (1990–2021): An Analysis of Trends and Health Inequalities Based on the Study of Global Burden of Disease 2021	42
Acknowledgment of Reviewers 2021	42
Individualized Risk Prediction for Improved Chronic Wound Management	42
From Chronic Wounds to Scarring: The Growing Health Care Burden of Under- and Over-Healing Wounds	42
Patterns of Co-Occurring Pressure Injuries: A Data-Driven Study Using Real-World Clinical Records	38
Advancing Therapeutic Solutions for Burn Wounds: Potential Use of Noninvasive Ultrasound-Driven Splenic Stimulation	38
Incisional Negative Pressure Wound Therapy Versus Primary Wound Suturing after Intestinal Ostomy Closure: A Systematic Review and Meta-Analysis	36
Prevalent Types of Peristomal Skin Damage During Chemoradiotherapy and Their Risk Factors	36
Extrusion-Based 3D Bioprinting of Bioactive and Piezoelectric Scaffolds as Potential Therapy for Treating Critical Soft Tissue Wounds	33
In Sequence Antifibrotic Treatment and Rehabilitation after Volumetric Muscle Loss Injury	33
Counting the Cost of Cellular and/or Tissue-Based Products in Diabetic Foot Ulcers: Is There a Justifiable Price Limit per Square Centimeter?	33
Image-Based Artificial Intelligence in Wound Assessment: A Systematic Review	32
Effects of ON101 for Hard-to-Heal Diabetic Foot Ulcers in a Randomized Phase III Trial: A Post Hoc Analysis	31
Effects of a New Enzymatic Debrider (SN514-066b) on Eschar Protein Digestion, Burn Wound Debridement, and Healthy Skin Irritation	31
An Evidence Map of Clinical Practice Guideline Recommendations and Quality on Venous Leg Ulcer	30
Integration of Flow Cytometry and Single-Cell RNA Sequencing Analysis to Explore the Fibroblast Subpopulations in Keloid that Correlate with Recurrence	30
Reliability of an AI-Powered Application Across Different Mobile Devices for Assessment of Chronic Wounds	29

Unlocking the Potential of Induced Pluripotent Stem Cells for Wound Healing: The Next Frontier of Regenerative Medicine	28
Genetics and Epigenetics of Keloids	28
Multidimensional Pain Characteristics in Older Adults with Chronic Venous Leg Ulcers	28
Structured Exercise Therapy Increases Endogenous Antioxidants to Repair Muscle Strength and Health in Porcine Ischemic Myopathy Model of Peripheral Artery Disease	27
Prediction Models for Intraoperative Acquired Pressure Injury of Adults: A Systematic Review and Critical Appraisal	26
Global Burden of Pressure Ulcer and Contributing Factors from 1990 to 2021: A Systematic Analysis with Forecasts to 2035	25
Prophylactic Negative Pressure Wound Therapy in Reducing Surgical Site Infections in Closed Abdominal Incision: A Randomized Controlled Trial	25
A Scoping Review of the Methodology Used in Studies of Genetic Influences on the Development of Keloid or Hypertrophic Scarring in Adults and Children After Acute Wounding	24
Multifunctional Elastin-Like Polypeptide Fusion Protein Coacervates Inhibit Receptor-Mediated Proinflammatory Signals and Promote Angiogenesis in Mouse Diabetic Wounds	22
Moisturizers, Emollients, or Barrier Preparations for the Prevention of Pressure Injury: A Systematic Review and Meta-Analysis	21
Noninferiority of Copper Dressings Than Negative Pressure Wound Therapy in Healing Diabetic Wounds: A Randomized Clinical Trial	21
The Promising Hydrogel Candidates for Preclinically Treating Diabetic Foot Ulcer: A Systematic Review and Meta-Analysis	21
Current Overview of Obesity-Induced Lymphedema	20
Using Three-Dimensional Bioprinting to Generate Realistic Models of Wound Healing	20
Innovations in Stem Cell Therapy for Diabetic Wound Healing	20
Split-Thickness Skin and Dermal Pixel Grafts Can Be Expanded up to 500 Times to Re-Epithelialize a Full-Thickness Burn Wound	20
How Should Clinical Wound Care and Management Translate to Effective Engineering Standard Testing Requirements from Foam Dressings? Mapping the Existing Gaps and Needs	19
The Association Between Risk-Adjusted Wound Healing Rates and Long-Term Outcomes in a Network of U.S. Wound Care Clinics	19
Understanding Scarring in the Oral Mucosa	19
Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat Accelerates Wound Healing in a Mouse Hind limb Lymphedema Model	18
Acknowledgment of Reviewers 2022	18
Novel Topical Esmolol Hydrochloride (Galnobax) for Diabetic Foot Wound: Phase 1/2, Multicenter, Randomized, Double-Blind, Vehicle-Controlled Parallel-Group Study	18
Correction to: Reduced Hospitalizations and Amputations in Patients with Diabetic Foot Ulcers Treated with Cyclical Pressurized Topical Wound Oxygen Therapy: Real-World Outcomes, by Izhakoff Ye	18
Pulse Capacitive Coupling Electric Field Regulates Cell Migration, Proliferation, Polarization, and Vascularization to Accelerate Wound Healing	17
The Science of Skin: Measuring Damage and Assessing Risk	17
Trends and Innovation in Negative Pressure Wound Therapy: A Review of Burn Wound Management	17
Human Amniotic Membrane Promotes Angiogenesis in an Oxidative Stress Chronic Diabetic Murine Wound Model	17
Associations Among Wound-Related Factors Including Biofilm, Wound-Related Symptoms and Systemic Inflammation in Older Adults with Chronic Venous Leg Ulcers	17
Early Intensified Rehabilitation Training with Hyperbaric Oxygen Therapy Improves Functional Disorders and Prognosis of Patients with Traumatic Brain Injury	16
Smoking Status Impacts Mitochondrial Function and Synthetic Function in Mesenchymal Stem Cells Derived from Diabetics with Arterial Insufficiency	16
Lineage Mapping of Extracellular Vesicles: What Cells Do They Come from and Where Do They Go?	15
Acellular Adipose Matrices Seem to Be an Effective and Safe Strategy for Soft Tissue Regeneration and Volume Restoration: A Systematic Review of Clinically Relevant Literature	15
Inflammation in Wound Healing and Pathological Scarring	15
Chemotherapy-Mediated Complications of Wound Healing: An Understudied Side Effect	15
The Pathophysiology and Management of Pathologic Scarring—a Contemporary Review	15
Skin Inflammation with a Focus on Wound Healing	15
Approaches to Modulate the Chronic Wound Environment Using Localized Nucleic Acid Delivery	14
Nitrous Oxide to Reduce Wound Care–Related Pain in Adults: A Systematic Review and Meta-Analysis	14
Debridement of Diabetic Foot Ulcers	13
Acknowledgment of Reviewers 2023	13
Cerium Nitrate Stiffens In Vitro Skin Models and Reduces Pseudomonas aeruginosa Pathogenicity and Penetration Through Skin Models	13
The Shizuoka Study of a Population-Based Retrospective Cohort for the Evaluation of Risk of Pressure Injury in the Elderly	13
Tissue Engineering-Based Strategies for Diabetic Foot Ulcer Management	13
Nanosheet Promotes Chronic Wound Healing by Localizing Uncultured Stromal Vascular Fraction Cells	12
Biosponge-Encased Placental Stem Cells for Volumetric Muscle Loss Repair	12
The WOUND-Q Function and Symptoms Scales for Chronic Lower Extremity Wounds: A Validation Study	11
Prosthetic Disuse Leads to Lower Balance Confidence in a Long-Term User of a Transtibial Prosthesis	11
The Analgesic Benefits of Ketorolac to Local Anesthetic Wound Infiltration Is Statistically Significant But Clinically Unimportant: A Comprehensive Systematic Review and Meta-Analysis	11
Re-Ulceration Is Common in Persons with Diabetes and Healed Foot Ulcer After Participant-Driven Education in Group: A Randomized Controlled Trial	11
Re: “A Novel Randomized Trial Protocol for Evaluating Wound Healing Interventions” by Bull et al.	10

Artificial Skin Therapies; Strategy for Product Development	9
Dermal Fibroblast Heterogeneity and Its Contribution to the Skin Repair and Regeneration	9
Alpha-1-Antitrypsin Enhances Fat Graft Survival in a Murine Model	8
Current Methodologies for Inducing Aligned Myofibers in Tissue Constructs for Skeletal Muscle Tissue Regeneration	8
A First-in-Human Randomized Clinical Study Investigating the Safety and Tolerability of Stabilized Hypochlorous Acid in Patients with Chronic Leg Ulcers	8
Approaches for Regenerative Healing of Cutaneous Wound with an Emphasis on Strategies Activating the Wnt/β-Catenin Pathway	8
The Effect of Telemedicine Interventions on Patients with Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials	8
Moist Wound Healing with Commonly Available Dressings	8
New Opportunities for Electric Fields in Promoting Wound Healing: Collective Electrotaxis	8
The Relationship Between Autoimmune Disease and Disease-Modifying Antirheumatic Drugs on Wound Healing	8
Topical Reconstituted High-Density Lipoproteins Elicit Anti-Inflammatory Effects in Diabetic Wounds	8
Targeting Anaerobic Respiration in Pseudomonas aeruginosa with Chlorate Improves Healing of Chronic Wounds	8
Mechanical Strain Drives Myeloid Cell Differentiation Toward Proinflammatory Subpopulations	7
Testosterone Promotes Nerve Tethering and Acellular Biomaterial Perineural Fibrosis in a Rat Wound Repair Model	7
Use of Therapeutic RNAs to Accelerate Wound Healing in Diabetic Rabbit Wounds	7
Switching from Galenic to Advanced Dressings or Vacuum Assisted Closure Therapy Can Improve Quality of Life of Patients with Chronic Non-Responsive Pressure Skin Ulcers: Preliminary Data with Italian	7
Recent Advances in Functional Wound Dressings	7
Comparative Effectiveness of Negative Pressure Wound Therapy with and Without Oxidized Regenerated Cellulose/Collagen/Silver-ORC Dressing	6
The Role of Hydrogel Biomaterials in the Intervention of Wound Healing and Skin Regeneration via Exosomes: A Systematic Review and Meta-Analysis of Preclinical Animal Studies	6
The Effectiveness of 595-nm Pulsed Dye Laser for the Treatment of Bilateral Cleft-Lip Scars in Asian Patients: A 6-Month Prospective, Randomized, Self-Controlled Trial	6
Prediction of Healing Trajectory of Chronic Wounds Using a Machine Learning Approach	6
Classification of Distinct Endotypes in Human Skin Scarring: S.C.A.R.—A Novel Perspective on Dermal Fibrosis	6
Systematic Review of Relevant Biomarkers for Human Connective Tissue Repair and Healing Outcome: Implications for Understanding Healing Processes and Design of Healing Interventions	6
Reporting of Financial Conflicts of Interest in Studies of Placental Membrane Allografts	6
Clinical Measurement of Transepidermal Water Loss	6
A Review of Hypertrophic Scar and Keloid Treatment and Prevention in the Pediatric Population: Where Are We Now?	6
Gelatin Microspheres Loaded with Wharton's Jelly Mesenchymal Stem Cells Promote Acute Full-Thickness Skin Wound Healing and Regeneration in Mice	6
Bridging the Gap: Contemporary Paradigms in Nerve Scaffolds and Regeneration	6
In Vitro,Ex Vivo, andIn VivoApproaches for Investigation of Skin Scarring: Human and Animal Models	6
Chondrocyte Mitochondrial Quality Control: A Novel Insight into Osteoarthritis and Cartilage Regeneration	5
Updates on Excisional Procedures for Lymphedema	5
Negative Pressure Wound Therapy: Challenges, Novel Techniques, and Future Perspectives	5
Deferoxamine to Minimize Fibrosis During Radiation Therapy	5
Wounds and Skin and Soft Tissue Infections in People Who Inject Drugs and the Utility of Syringe Service Programs in Their Management	5
Magnetic Resonance Imaging Techniques in Peripheral Arterial Disease	5
A Novel Xenograft Model Demonstrates Human Fibroblast Behavior During Skin Wound Repair and Fibrosis	5
Strategies to Minimize Surgical Scarring: Translation of Lessons Learned from Bedside to Bench and Back	5
Current Understanding of Pathological Mechanisms of Lymphedema	4
Exploring the Overlooked Roles and Mechanisms of Fibroblasts in the Foreign Body Response	4
Comparison of “Semiocclusive Dressing” Treatment Using Plastic Wrap or Low-Adherent Absorbent Wound Dressings Versus Occlusive Dressing Treatment for Stage III/IV Pressure Injuries in the Inflammatory	4
Response to Astrada et al. re: “A Novel Randomized Trial Protocol for Evaluating Wound Healing Interventions”	4
Treatment of Surgical Scars with Fractional Carbon Dioxide (CO₂) Laser: A Randomized Controlled Trial	4
AI-Powered Image-Based Assessment of Pressure Injuries Using You Only Look once (YOLO) Version 8 Models	4
Re: “How Should Clinical Wound Care and Management Translate to Effective Engineering Standard Testing Requirements from Foam Dressings? Mapping the Existing Gaps and Needs” by Gefen et al.	4
Modulation of Lymphangiogenesis in Incisional Murine Diabetic Wound Healing Using Negative Pressure Wound Therapy	4
Alginate Formulation for Wound Healing Applications	4
Behind the Scenes of Extracellular Vesicle Therapy for Skin Injuries and Disorders	4
Rosalind Franklin Society Proudly Announces the 2023 Award Recipient for Advances in Wound Care	4
Acellular Scaffolds for Muscle Regeneration: Advances and Challenges	4
Pharmaceutical Prophylaxis of Scarring with Emphasis on Burns: A Review of Preclinical and Clinical Studies	4
Assessment of Patient-Reported Outcomes for Closed-Incision Negative Pressure Therapy with Wide-Coverage Dressings in Simple Mastectomy and Immediate Implant-Based Breast Reconstruction	4
A Prospective, Randomized, Controlled Study to Evaluate the Effectiveness of a Fabric-Based Wireless Electroceutical Dressing Compared to Standard-of-Care Treatment Against Acute Trauma and Burn Wound	4
HMGB1 Accelerates Wound Healing by Promoting the Differentiation of Epidermal Stem Cells via the “HMGB1-TLR4-Wnt/Notch” Axis	4
Cerium Nitrate Treatment in the Management of Burns	4
Single-Cell Proteomics Uncovers Dual Traits of Dermal Sheath Cells in Wound Repair	4
Antimicrobial Peptides for Diabetic Wound Healing: Preclinical and Clinical Studies	4