OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Therapy-Nucleic Acids is 44. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
MicroRNA-466 and microRNA-200 increase endothelial permeability in hyperglycemia by targeting Claudin-5	153
All roads lead to cure: Diversity of oligonucleotides in DM1 therapy	118
Inefficacy of anti-VEGF therapy reflected in VEGF-mediated photoreceptor degeneration	86
Insights into the regulatory role of epigenetics in moyamoya disease: Current advances and future prospectives	77
Endothelial derived, secreted long non-coding RNAs Gadlor1 and Gadlor2 aggravate cardiac remodeling	75
Effective intravitreal gene delivery to retinal pigment epithelium with hyaluronic acid nanospheres	74
Activating the Cpx response induces tolerance to antisense PNA delivered by an arginine-rich peptide in Escherichia coli	74
Gene-repressing epigenetic reader EED unexpectedly enhances cyclinD1 gene activation	71
Cas-CLOVER is a novel high-fidelity nuclease for safe and robust generation of TSCM-enriched allogeneic CAR-T cells	70
LinQURE: A novel AAV gene silencing platform that supports multi-transcript targeting for complex disorders	69
AAV-vectored base editor trans-splicing delivers dystrophin repair	69
RETRACTED: H3K27 demethylase KDM6B aggravates ischemic brain injury through demethylation of IRF4 and Notch2-dependent SOX9 activation	69
Retraction Notice to: Hypoxic tumor-derived exosomal circular RNA SETDB1 promotes invasive growth and EMT via the miR-7/Sp1 axis in lung adenocarcinoma	68
HOXA5-miR-574-5p axis promotes adipogenesis and alleviates insulin resistance	67
Combining nonsense mutation suppression therapy with nonsense-mediated decay inhibition in neurofibromatosis type 1	65
Single-swap editing for the correction of common Duchenne muscular dystrophy mutations	65
A bimolecular modification strategy for developing long-lasting bone anabolic aptamer	65
Exosomal miR-590-3p derived from cancer-associated fibroblasts confers radioresistance in colorectal cancer	65
Modulation of miR-29 influences myocardial compliance likely through coordinated regulation of calcium handling and extracellular matrix	63
Implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer’s disease	63
Antisense oligonucleotide-mediated exon 27 skipping restores dysferlin function in dysferlinopathy patient-derived muscle cells	62
Unlocking RNA mysteries: Predicting subcellular localizations with AI	62
Emerging roles of circRNAs in the pathological process of myocardial infarction	59
Forced enhancer-promoter rewiring to alter gene expression in animal models	59
Mitochondrial double-stranded RNAs as a pivotal mediator in the pathogenesis of Sjӧgren’s syndrome	58

Alleviation of ischemia-reperfusion induced renal injury by chemically modified SOD2 mRNA delivered via lipid nanoparticles	57
Novel insights into the interaction between N6-methyladenosine modification and circular RNA	56
Enhanced molecular dynamic simulation studies unravel long-range effects caused by sequence variations and partner binding in RNA aptamers	56
Highly efficient A-to-G base editing by ABE8.17 in rabbits	55
Single-cell transcriptome profiling implicates the psychological stress-induced disruption of spermatogenesis	54
Efficient transfected liposomes co-loaded with pNrf2 and pirfenidone improves safe delivery for enhanced pulmonary fibrosis reversion	52
Right on target: The next class of efficient, safe, and specific RNAi triggers	51
Engineering B cells with customized therapeutic responses using a synthetic circuit	51
tRF-1001: A potential therapeutic target for ocular neovascular diseases	51
RNA therapeutics in targeting G protein-coupled receptors: Recent advances and challenges	49
Structural variants and modifications of hammerhead ribozymes targeting influenza A virus conserved structural motifs	49
CleanCap M6 inhibits decapping of exogenously delivered IVT mRNA	48
DNA-PKcs inhibition improves sequential gene insertion of the full-length CFTR cDNA in airway stem cells	48
Nucleic acid delivery for pathology treatment: RNA tissue delivery	47
Redefining NSP12 activity in SARS-CoV-2 and its regulation by NSP8 and NSP7	47
Extracellular viral microRNAs as biomarkers of virus infection in human cells	47
miR-6077 promotes cisplatin/pemetrexed resistance in lung adenocarcinoma via CDKN1A/cell cycle arrest and KEAP1/ferroptosis pathways	46
miR-204 suppresses cancer stemness and enhances osimertinib sensitivity in non-small cell lung cancer by targeting CD44	45
HnRNP-L-regulated circCSPP1/miR-520h/EGR1 axis modulates autophagy and promotes progression in prostate cancer	44
Cancer immunomodulation using bispecific aptamers	44
Joint masking and self-supervised strategies for inferring small molecule-miRNA associations	44
Double-stranded RNA induction asa potential dynamic biomarkerfor DNA-demethylating agents	44
Precise detection of CRISPR-Cas9 editing in hair cells in the treatment of autosomal dominant hearing loss	44
Inhibition of microRNA-30a alleviates vascular remodeling in pulmonary arterial hypertension	44