OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Therapy-Nucleic Acids is 47. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
All roads lead to cure: Diversity of oligonucleotides in DM1 therapy	151
Modulation of miR-29 influences myocardial compliance likely through coordinated regulation of calcium handling and extracellular matrix	99
Endothelial derived, secreted long non-coding RNAs Gadlor1 and Gadlor2 aggravate cardiac remodeling	90
A bimolecular modification strategy for developing long-lasting bone anabolic aptamer	88
RETRACTED: HOXA5-miR-574-5p axis promotes adipogenesis and alleviates insulin resistance	85
Efficient transfected liposomes co-loaded with pNrf2 and pirfenidone improves safe delivery for enhanced pulmonary fibrosis reversion	84
Single-swap editing for the correction of common Duchenne muscular dystrophy mutations	79
MicroRNA-466 and microRNA-200 increase endothelial permeability in hyperglycemia by targeting Claudin-5	79
Forced enhancer-promoter rewiring to alter gene expression in animal models	78
Gene-repressing epigenetic reader EED unexpectedly enhances cyclinD1 gene activation	78
Emerging roles of circRNAs in the pathological process of myocardial infarction	78
Cas-CLOVER is a novel high-fidelity nuclease for safe and robust generation of TSCM-enriched allogeneic CAR-T cells	77
Retraction Notice to: Hypoxic tumor-derived exosomal circular RNA SETDB1 promotes invasive growth and EMT via the miR-7/Sp1 axis in lung adenocarcinoma	70
Mitochondrial double-stranded RNAs as a pivotal mediator in the pathogenesis of Sjӧgren’s syndrome	70
Alleviation of ischemia-reperfusion induced renal injury by chemically modified SOD2 mRNA delivered via lipid nanoparticles	69
Effective intravitreal gene delivery to retinal pigment epithelium with hyaluronic acid nanospheres	68
Insights into the regulatory role of epigenetics in moyamoya disease: Current advances and future prospectives	66
SPRINGing forward: Advancing RNA editing efficiency and precision with engineered ADAR2	66
Novel insights into the interaction between N6-methyladenosine modification and circular RNA	64
Highly efficient A-to-G base editing by ABE8.17 in rabbits	63
Antisense oligonucleotide-mediated exon 27 skipping restores dysferlin function in dysferlinopathy patient-derived muscle cells	62
Single-cell transcriptome profiling implicates the psychological stress-induced disruption of spermatogenesis	62
AAV-vectored base editor trans-splicing delivers dystrophin repair	60
LinQURE: A novel AAV gene silencing platform that supports multi-transcript targeting for complex disorders	58
Implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer’s disease	57

Unlocking RNA mysteries: Predicting subcellular localizations with AI	56
An oversized AAV8 vector to deliver CPS1	56
Durable HTT silencing using non-evolved dCas9 epigenome editors in patient-derived cells	55
Ferroptosis as a therapeutic target in glioblastoma: Mechanisms and emerging strategies	52
A potent GalNAc-siRNA drug, RBD1016, leads to sustained HBsAg reduction and seroconversion in mouse models of HBV infection	52
Implications of circular transcripts in DM1 pathomechanism	52
Combining nonsense mutation suppression therapy with nonsense-mediated decay inhibition in neurofibromatosis type 1	51
Discovery of peptides for ligand-mediated delivery of mRNA lipid nanoparticles to cystic fibrosis lung epithelia	51
Enhanced molecular dynamic simulation studies unravel long-range effects caused by sequence variations and partner binding in RNA aptamers	51
Inefficacy of anti-VEGF therapy reflected in VEGF-mediated photoreceptor degeneration	51
RNA therapeutics in targeting G protein-coupled receptors: Recent advances and challenges	51
Antitumor effects of chemically modified miR-143 lipoplexes in a mouse model of pelvic colorectal cancer via myristoylated alanine-rich C kinase substrate downregulation	50
RETRACTED: LncRNA PVT1 promotes tumorigenesis of glioblastoma by recruiting COPS5 to deubiquitinate and stabilize TRIM24	50
A conditional RNA Pol II mono-promoter drives HIV-inducible, CRISPR-mediated cyclin T1 suppression and HIV inhibition	50
Topical application of a CCL22-binding aptamer suppresses contact allergy	49
Extracellular viral microRNAs as biomarkers of virus infection in human cells	49
Towards SINEUP-based therapeutics: Design of an in vitro synthesized SINEUP RNA	49
Redefining NSP12 activity in SARS-CoV-2 and its regulation by NSP8 and NSP7	49
CleanCap M6 inhibits decapping of exogenously delivered IVT mRNA	48
Unlocking the therapeutic potential of locked nucleic acids through lipid nanoparticle delivery	48
miR-204 suppresses cancer stemness and enhances osimertinib sensitivity in non-small cell lung cancer by targeting CD44	48
Heterogeneity of human corneal endothelium implicates lncRNA NEAT1 in Fuchs endothelial corneal dystrophy	48
A genome-wide CRISPR screen unveils the endosomal maturation protein WDR91 as a promoter of productive ASO activity in melanoma	47
DNA-PKcs inhibition improves sequential gene insertion of the full-length CFTR cDNA in airway stem cells	47
Deficiency of miR-409-3p improves myocardial neovascularization and function through modulation of DNAJB9/p38 MAPK signaling	47