Molecular Therapy-Nucleic Acids

Papers
(The TQCC of Molecular Therapy-Nucleic Acids is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
Retraction Notice to: circFMN2 Sponges miR-1238 to Promote the Expression of LIM-Homeobox Gene 2 in Prostate Cancer Cells153
RETRACTED: lncRNA ILF3-AS1 promotes proliferation and metastasis of colorectal cancer cells by recruiting histone methylase EZH2111
Retraction Notice to: circIFT80 Functions as a ceRNA of miR-1236-3p to Promote Colorectal Cancer Progression82
Retraction Notice to: hsa_circ_001653 Implicates in the Development of Pancreatic Ductal Adenocarcinoma by Regulating MicroRNA-377-MediatedHOXC6 Axis75
Retraction Notice to: Silencing of Long Non-coding RNA HOTTIP Reduces Inflammation in Rheumatoid Arthritis by Demethylation of SFRP174
Retraction Notice to: Growth Arrest-Specific Transcript 5 (GAS5) Exerts Important Roles on the Treatment of BM45 Cells of Liver Cirrhosis73
Retraction Notice to: Circular RNA Profiling Reveals Exosomal circ_0006156 as a Novel Biomarker in Papillary Thyroid Cancer72
Lockpicking FGFR1 with aptamer-based technology69
Retraction Notice to: MicroRNA-140 Inhibits the Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer69
Multi-omics and machine learning-driven CD8+ T cell heterogeneity score for head and neck squamous cell carcinoma67
Transcriptomic analysis of the immune response to in vivo gene electrotransfer in colorectal cancer65
Gal-3 activates Tyro3 to ameliorate ferroptosis of hippocampal neurons after traumatic brain injury65
Targeted allele-specific FGFR2 knockdown via human recombinant ferritin nanoparticles for personalized treatment of Crouzon syndrome63
miR-429 RNA therapy as generic strategy to protect against photoreceptor loss63
i-Motifs as regulatory switches: Mechanisms and implications for gene expression63
TMEM97 governs partial epithelial-mesenchymal transition of retinal pigment epithelial cells via the CTNND2-ADAM10 axis63
In vivo production of engineered ACE2 decoy protects lungs from SARS-CoV-2 infection63
Unlocking the potential of allele-specific siRNA therapy: A novel approach for Crouzon syndrome62
Use of polyadenosine tail mimetics to enhance mRNA expression from genes associated with haploinsufficiency disorders62
lncRNA localization and feature interpretability analysis61
FTO deficiency facilitates epithelia dysfunction in oral lichen planus61
Impact on efficacy of target reduction of two FDA-approved ASO drugs by intracellular glucose levels in in vitro cell models60
Antisense oligonucleotide-mediated exon 27 skipping restores dysferlin function in dysferlinopathy patient-derived muscle cells59
Harnessing defective interfering particles and lipid nanoparticles for effective delivery of an anti-dengue virus RNA therapy59
Unlocking RNA mysteries: Predicting subcellular localizations with AI55
HOXA5-miR-574-5p axis promotes adipogenesis and alleviates insulin resistance54
mitoTALEN reduces the mutant mtDNA load in neurons54
Liposome-mediated small RNA delivery to convert the macrophage polarity: A novel therapeutic approach to treat inflammatory uterine disease53
RETRACTED: H3K27 demethylase KDM6B aggravates ischemic brain injury through demethylation of IRF4 and Notch2-dependent SOX9 activation52
Retraction Notice to: Hypoxic tumor-derived exosomal circular RNA SETDB1 promotes invasive growth and EMT via the miR-7/Sp1 axis in lung adenocarcinoma51
Retraction Notice to: lncRNA MALAT1 Accelerates Wound Healing of Diabetic Mice Transfused with Modified Autologous Blood via the HIF-1α Signaling Pathway51
hsa_circ_0005358 suppresses cervical cancer metastasis by interacting with PTBP1 protein to destabilize CDCP1 mRNA49
Mechanism of action of hepatitis B virus S antigen transport-inhibiting oligonucleotide polymer, STOPS, molecules49
Engineering miRNA features into siRNAs: Guide-strand bulges are compatible with gene repression49
Epigenetic and nanotechnology alliance to fight stroke-induced brain damage48
Long noncoding RNA LUCAT1 enhances the survival and therapeutic effects of mesenchymal stromal cells post-myocardial infarction48
Exploring the potential of Salmonella-mediated anti-sense RCAS1 RNA therapy in combatting aggressive breast cancer48
Modulation of experimental acute lung injury by exosomal miR-7704 from mesenchymal stromal cells acts through M2 macrophage polarization46
Sharper scissors: How TREX2 fine-tunes CRISPR-Cas9 nickases for precise editing46
DNA minicircles as novel STAT3 decoy oligodeoxynucleotides endowed with anticancer activity in triple-negative breast cancer45
Forced enhancer-promoter rewiring to alter gene expression in animal models45
Bridging siRNA strands for better function44
Treatment of CHO cells with Taxol and reversine improves micronucleation and microcell-mediated chromosome transfer efficiency44
PINE-TREE enables efficient enrichment of prime-edited hPSCs43
Unveiling ATF6 and PPM1H signaling in hepatocellular carcinoma progression: From ER stress to tumor suppression43
Emerging roles of circRNAs in the pathological process of myocardial infarction42
MicroRNA-466 and microRNA-200 increase endothelial permeability in hyperglycemia by targeting Claudin-542
Predicting transcription factor binding sites using DNA shape features based on shared hybrid deep learning architecture42
miR-940 is a new biomarker with tumor diagnostic and prognostic value42
Retraction Notice to: lncRNA GAS5 Inhibits Cell Migration and Invasion and Promotes Autophagy by Targeting miR-222-3p via the GAS5/PTEN-Signaling Pathway in CRC42
Dysregulation of the miRNome unveils a crosstalk between obesity and prostate cancer: miR-107 asa personalized diagnostic and therapeutic tool42
RAB18 is a key regulator of GalNAc-conjugated siRNA-induced silencing in Hep3B cells42
Subretinal gene therapy delays vision loss in a Bardet-Biedl Syndrome type 10 mouse model41
Combining nonsense mutation suppression therapy with nonsense-mediated decay inhibition in neurofibromatosis type 141
Efficient shRNA-based knockdown of multiple target genes for cell therapy using a chimeric miRNA cluster platform41
MicroRNA-451a inhibits gemcitabine-refractory biliary tract cancer progression by suppressing the MIF-mediated PI3K/AKT pathway41
Inhaled aptamer therapy: A hopeful therapy for lung disease40
Novel readthrough agent suppresses nonsense mutations and restores functional type VII collagen and laminin 332 in epidermolysis bullosa40
Progress and harmonization of gene editing to treat human diseases: Proceeding of COST Action CA21113 GenE-HumDi40
miR-125b Upregulates miR-34a and Sequentially Activates Stress Adaption and Cell Death Mechanisms in Multiple Myeloma39
A drug candidate for a rare polyalanine disease targeting the protein quality control39
Inhaled aptamer therapy: A hopeful therapy for lung disease39
Optimization of mtDNA-targeted platinum TALENs for bi-directionally modifying heteroplasmy levels in patient-derived m.3243A>G-iPSCs39
The Aptamer Ob2, a novel AChE inhibitor, restores cognitive deficits and alleviates amyloidogenesis in 5×FAD transgenic mice38
Leverage of nuclease-deficient CasX for preventing pathological angiogenesis38
Sustained therapeutic benefits by transient reduction of TDP-43 using ENA-modified antisense oligonucleotides in ALS/FTD mice38
Anti-TGF-β1 aptamer enhances therapeutic effect of tyrosine kinase inhibitor, gefitinib, on non-small cell lung cancer in xenograft model38
Farnesylthiosalicylic acid-derivatized PEI-based nanocomplex for improved tumor vaccination38
Effective gene therapy of Stargardt disease with PEG-ECO/pGRK1-ABCA4-S/MAR nanoparticles38
AntimiR targeting of microRNA-134 reduces seizures in a mouse model of Angelman syndrome37
Suppression of endothelial miR-22 mediates non-small cell lung cancer cell-induced angiogenesis37
EPRIM: An approach of identifying cancer immune-related epigenetic regulators37
Loss of full-length pumilio 1 abrogates miRNA-221-induced gene p27 silencing-mediated cell proliferation in the heart37
Engineering an adenine base editor in human embryonic stem cells with minimal DNA and RNA off-target activities37
Serum lncRNAs in early pregnancy as potential biomarkers for the prediction of pregnancy-induced hypertension, including preeclampsia36
Viral protein revives host cell miRNA function by dampening the circular RNA sponge35
Construction of a Myc-associated ceRNA network reveals a prognostic signature in hepatocellular carcinoma35
Streamlined DNA-encoded small molecule library screening and validation for the discovery of novel chemotypes targeting BET proteins35
Exploring pulmoprotection in COVID-19: Moving toward microRNA-based theranostics34
Phosphatidylcholine head group chemistry alters the extrahepatic accumulation of lipid-conjugated siRNA34
Rheb-mTOR activation rescues Aβ-induced cognitive impairment and memory function by restoring miR-146 activity in glial cells34
PINE-TREE enables highly efficient genetic modification of human cell lines34
Gene-repressing epigenetic reader EED unexpectedly enhances cyclinD1 gene activation34
RNA nanoparticles for targeted therapies of triple-negative breast cancers34
Unveiling the emerging functions of nuclear actin in gene function regulation33
Future of biotherapeutics: Harnessing mRNA to enhance elastin expression32
Selective suppression of polyglutamine-expanded protein by lipid nanoparticle-delivered siRNA targeting CAG expansions in the mouse CNS32
RETRACTED: MTTL3 upregulates microRNA-1246 to promote occurrence and progression of NSCLC via targeting paternally expressed gene 332
Deletion of miR-146a enhances therapeutic protein restoration in model of dystrophin exon skipping32
Toward learning the rules that predict siRNA efficacy32
Lateral flow immunoassay for rapid and sensitive detection of dsRNA contaminants in in vitro-transcribed mRNA products32
Insights into the regulatory role of epigenetics in moyamoya disease: Current advances and future prospectives31
Superior efficacy of a skin-applied microprojection device for delivering a novel Zika DNA vaccine31
circNUDT21 promotes bladder cancer progression by modulating the miR-16-1-3p/MDM2/p53 axis31
Neuronal-type-specific epigenome editing to decrease SNCA expression: Implications for precision medicine in synucleinopathies31
A neutralizable dimeric anti-thrombin aptamer with potent anticoagulant activity in mice31
Cooperative activation of human TLR9 and consequences for the clinical development of antisense and CpG oligodeoxynucleotides31
LINC01189-miR-586-ZEB1 feedback loop regulates breast cancer progression through Wnt/β-catenin signaling pathway31
Binding characterization of anthraquinone derivatives by stabilizing G-quadruplex DNA leads to an anticancerous activity30
Adeno-associated virus-based gene therapy delivering combinations of two growth-associated genes to MPS IVA mice30
A cystic fibrosis gene editing approach that is on target30
Inefficacy of anti-VEGF therapy reflected in VEGF-mediated photoreceptor degeneration30
Role of miR-300-3p in Leydig cell function and differentiation: A therapeutic target for obesity-related testosterone deficiency30
All roads lead to cure: Diversity of oligonucleotides in DM1 therapy30
rAAV-delivered PTEN therapeutics for prostate cancer30
Evaluation of the effect of RNA secondary structure on Cas13d-mediated target RNA cleavage30
Endothelial derived, secreted long non-coding RNAs Gadlor1 and Gadlor2 aggravate cardiac remodeling30
Unveiling the intricacies of gene delivery: Caveolae-mediated endocytosis induces efficient mRNA delivery in slow-dividing cells29
Exon 44 skipping in Duchenne muscular dystrophy: NS-089/NCNP-02, a dual-targeting antisense oligonucleotide29
Global characterization of RNA editing in genetic regulation of multiple ovarian cancer subtypes29
Lipopeptide-mediated Cas9 RNP delivery: A promising broad therapeutic strategy for safely removing deep-intronic variants in ABCA429
Translatomics to explore dynamic differences in immunocytes in the tumor microenvironment29
Anti-miR-141-3p maintains homeostasis between autophagy and apoptosis by targeting Yy1 in the fetal lumbosacral defecation center of rats28
Effective intravitreal gene delivery to retinal pigment epithelium with hyaluronic acid nanospheres28
Cell-type-specific alternative polyadenylation as a therapeutic biomarker in lung cancer progression28
Modulation of miR-29 influences myocardial compliance likely through coordinated regulation of calcium handling and extracellular matrix28
Lowering an ER stress-regulated long noncoding RNA protects mice from diabetes and isolated pancreatic islets from cell death28
Aptamer-decorated nanocarriers for viral adsorption: A special look at COVID-1928
Adenine base editing of the DUX4 polyadenylation signal for targeted genetic therapy in facioscapulohumeral muscular dystrophy28
Branchpoints as potential targets of exon-skipping therapies for genetic disorders28
Splice-switching antisense oligonucleotide controlling tumor suppressor REST is a novel therapeutic medicine for neuroendocrine cancer28
Rescue of the endogenous FVIII expression in hemophilia A mice using CRISPR-Cas9 mRNA LNPs28
Activating the Cpx response induces tolerance to antisense PNA delivered by an arginine-rich peptide in Escherichia coli28
BB-301: a silence and replace AAV-based vector for the treatment of oculopharyngeal muscular dystrophy27
ACEing premature codon termination using anticodon-engineered sup-tRNA-based therapy27
Sustainable recovery of MBNL activity in autoregulatory feedback loop in myotonic dystrophy27
Anti-EFG1 2′-OMethylRNA oligomer inhibits Candida albicans filamentation and attenuates the candidiasis in Galleria mellonella27
Efficient CRISPR-Cas9-mediated mutagenesis in primary human B cells for identifying plasma cell regulators27
Unraveling the epitranscriptome of small non-coding RNAs in vascular cells27
miR-379 mediates insulin resistance and obesity through impaired angiogenesis and adipogenesis regulated by ER stress27
Advancing peptide siRNA-carrier designs through L/D-amino acid stereochemical modifications to enhance gene silencing27
Cardiomyocyte mitochondrial dynamic-related lncRNA 1 (CMDL-1) may serve as a potential therapeutic target in doxorubicin cardiotoxicity27
Highly efficient A-to-G base editing by ABE8.17 in rabbits27
AAV-vectored base editor trans-splicing delivers dystrophin repair26
Minding the gap: Unlocking the therapeutic potential of aptamers and making up for lost time26
Peptide nanostructures-based delivery of DNA nanomaterial therapeutics for regulating gene expression26
LinQURE: A novel AAV gene silencing platform that supports multi-transcript targeting for complex disorders26
DNAJB6 isoform specific knockdown: Therapeutic potential for limb girdle muscular dystrophy D126
DNA/RNA heteroduplex technology with cationic oligopeptide reduces class-related adverse effects of nucleic acid drugs26
Cellular uptake of modified mRNA occurs via caveolae-mediated endocytosis, yielding high protein expression in slow-dividing cells26
Expression of NORAD correlates with breast cancer aggressiveness and protects breast cancer cells from chemotherapy25
Minicircle DNA vectors: A breakthrough in non-viral delivery of CRISPR base editors?25
Chimeric mRNA-based COVID-19 vaccine induces protective immunity against Omicron and Delta variants25
How well does the adaptive feature representation learning approach identify human mRNA N4-acetylcytidine sites?25
Evaluation of DNA minicircles for delivery of adenine and cytosine base editors using activatable gene on “GO” reporter imaging systems25
Nucleic acid amphiphiles: Synthesis, properties, and applications24
Retraction Notice to: Decreased Lung Tumor Development in SwAPP Mice through the Downregulation of CHI3L1 and STAT 3 Activity via the Upregulation of miRNA342-3p24
Restoration of functional PAX6 in aniridia patient iPSC-derived ocular tissue models using repurposed nonsense suppression drugs24
Retraction Notice to: miRNA-129/FBW7/NF-κB, a Novel Regulatory Pathway in Inflammatory Bowel Disease24
WITHDRAWN: SPOP Promotes Acute Myeloid Leukemia Initiation and Development Through miR-183-Mediated METAP2 Inhibition24
A terminal functionalization strategy reveals unusual binding abilities of anti-thrombin anticoagulant aptamers24
Novel Fas-TNFR chimeras that prevent Fas ligand-mediated kill and signal synergistically to enhance CAR T cell efficacy24
HIF-1α or HOTTIP/CTCF Promotes Head and Neck Squamous Cell Carcinoma Progression and Drug Resistance by Targeting HOXA924
The gene silencing of IRF5 and BLYSS effectively modulates the outcome of experimental lupus nephritis23
DdCBE mediates efficient and inheritable modifications in mouse mitochondrial genome23
Mechanistic Intracellular Pharmacokinetic/Pharmacodynamic Modeling to Inform Development Strategies for Small Interfering RNA Therapeutics23
Neutrophil-like cell membrane-coated siRNA of lncRNA AABR07017145.1 therapy for cardiac hypertrophy via inhibiting ferroptosis of CMECs23
PHF5A promotes colorectal cancer progression by alternative splicing of TEAD223
Ratio of miRNA-29 to miRNA-199 expression coordinates mesenchymal stem cell repair of bleomycin-induced pulmonary injury23
Inhibition of microRNA-494-3p activates Wnt signaling and reduces proinflammatory macrophage polarization in atherosclerosis23
Targeting Duchenne muscular dystrophy by skipping DMD exon 45 with base editors23
Cas-CLOVER is a novel high-fidelity nuclease for safe and robust generation of TSCM-enriched allogeneic CAR-T cells23
A bimolecular modification strategy for developing long-lasting bone anabolic aptamer23
Ruvkun and Ambros recognized for miRNAs23
Efficacy and safety of a SOD1-targeting artificial miRNA delivered by AAV9 in mice are impacted by miRNA scaffold selection23
Splicing correction by peptide-conjugated morpholinos as a novel treatment for Late-Onset Pompe Disease22
Therapeutic phosphorodiamidate morpholino oligonucleotides: Physical properties, solution structures, and folding thermodynamics22
Cell-targeted gene modification by delivery of CRISPR-Cas9 ribonucleoprotein complexes in pseudotyped lentivirus-derived nanoparticles22
Implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer’s disease22
Engineered deaminases as a key component of DNA and RNA editing tools22
The multifaceted roles of circular RNAs in cancer hallmarks: From mechanisms to clinical implications22
mRNA-based therapy in a rabbit model of variegate porphyria offers new insights into the pathogenesis of acute attacks22
Novel insights into the interaction between N6-methyladenosine modification and circular RNA22
Endoplasmic reticulum stress promotes sorafenib resistance via miR-188-5p/hnRNPA2B1-mediated upregulation of PKM2 in hepatocellular carcinoma22
Non-targeting control for MISSION shRNA library silences SNRPD3 leading to cell death or permanent growth arrest22
Multiplex HDR for disease and correction modeling of SCID by CRISPR genome editing in human HSPCs22
Single-cell transcriptome profiling implicates the psychological stress-induced disruption of spermatogenesis22
Mitochondrial double-stranded RNAs as a pivotal mediator in the pathogenesis of Sjӧgren’s syndrome22
Single-swap editing for the correction of common Duchenne muscular dystrophy mutations22
Enhanced molecular dynamic simulation studies unravel long-range effects caused by sequence variations and partner binding in RNA aptamers22
The regulatory roles of aminoacyl-tRNA synthetase in cardiovascular disease22
Efficient transfected liposomes co-loaded with pNrf2 and pirfenidone improves safe delivery for enhanced pulmonary fibrosis reversion22
MicroRNA-212-5p, an anti-proliferative miRNA, attenuates hypoxia and sugen/hypoxia-induced pulmonary hypertension in rodents21
Exosomal noncoding RNA: A potential therapy for retinal vascular diseases21
Essential role of ALKBH5-mediated RNA demethylation modification in bile acid-induced gastric intestinal metaplasia21
TAM-derived extracellular vesicles containing microRNA-29a-3p explain the deterioration of ovarian cancer21
Closing the gap: Nonviral TFAMoplex transfection boosted by bZIP domains compared to AAV mediated transfection21
Suppression of abnormal α-synuclein expression by activation of BDNF transcription ameliorates Parkinson’s disease-like pathology21
Alleviation of ischemia-reperfusion induced renal injury by chemically modified SOD2 mRNA delivered via lipid nanoparticles21
Prime editing optimized RTT permits the correction of the c.8713C>T mutation in DMD gene21
Expanded targeting scope of LbCas12a variants allows editing of multiple oncogenic mutations21
A pan-tumor-siRNA aptamer chimera to block nonsense-mediated mRNA decay inflames and suppresses tumor progression21
Proof of concept of peptide-linked blockmiR-induced MBNL functional rescue in myotonic dystrophy type 1 mouse model21
Proof-of-concept study for liver-directed miQURE technology in a dyslipidemic mouse model21
Exosomal non-coding RNAs have a significant effect on tumor metastasis21
Chemically modified MIR143-3p exhibited anti-cancer effects by impairing the KRAS network in colorectal cancer cells20
Can artificial intelligence-strengthened ChatGPT or other large language models transform nucleic acid research?20
miR-221/222 as biomarkers and targets for therapeutic intervention on cancer and other diseases: A systematic review20
ac4C-AFL: A high-precision identification of human mRNA N4-acetylcytidine sites based on adaptive feature representation learning20
Exosomal miR-590-3p derived from cancer-associated fibroblasts confers radioresistance in colorectal cancer20
cGAMP-adjuvanted multivalent influenza mRNA vaccines induce broadly protective immunity through cutaneous vaccination in mice20
ALKBH5-mediated m6A mRNA methylation governs human embryonic stem cell cardiac commitment20
Mechanical stimuli-induced CCL2 restores adult mouse cells to regenerate hair follicles20
Analysis and identification of m6A RNA methylation regulators in metastatic osteosarcoma20
HDAC inhibitors improve CRISPR-Cas9 mediated prime editing and base editing20
Depleting hepatitis B virus relaxed circular DNA is necessary for resolution of infection by CRISPR-Cas920
Artificial intelligence enabled ChatGPT and large language models in drug target discovery, drug discovery, and development20
Effective gene therapy for metachromatic leukodystrophy achieved with minimal lentiviral genomic integrations19
Construction of PANoptosis signature: Novel target discovery for prostate cancer immunotherapy19
Rapid molecular imaging of active thrombi in vivo using aptamer-antidote probes19
Retraction Notice to: Promotion of tumor progression by exosome transmission of circular RNA circSKA319
CleanCap M6 inhibits decapping of exogenously delivered IVT mRNA19
Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer19
Control of endothelial cell function and arteriogenesis by MEG3:EZH2 epigenetic regulation of integrin expression19
Single-cell profiling of mouse and primate ovaries identifies high levels of EGFR for stromal cells in ovarian aging19
Enhanced HDR-mediated correction of heterozygous COL7A1 mutations for recessive dystrophic epidermolysis bullosa19
Nucleic acid delivery for pathology treatment: RNA tissue delivery19
Extracellular viral microRNAs as biomarkers of virus infection in human cells19
piRNA/PIWI pathways and epigenetic crosstalk in human diseases: Molecular insights into HIV-1 infection and drugs of abuse19
Engineering cGAS-agonistic oligonucleotides as therapeutics for cancer immunotherapy19
Increasing angiogenesis factors in hypoxic diabetic wounds using siRNA nanotherapeutics19
Non-invasive detection of allele-specific CRISPR-SaCas9-KKH disruption of TOR1A DYT1 allele in a xenograft mouse model19
Clinical trial to compare safety and tolerability between intravenous infusion and bolus intravenous injection of ApTOLL in healthy volunteers19
In vivo efficacy and safety of systemically administered serinol nucleic acid-modified antisense oligonucleotides in mouse kidney19
The role of long non-coding RNAs in angiogenesis and anti-angiogenic therapy resistance in cancer18
Good news for the mdx mouse community: Improved dystrophin restoration after skipping mouse dystrophin exon 2318
Long-term muscle-specific overexpression of DOK7 in mice using AAV9-tMCK-DOK718
Genome editing before CRISPR: The gnostic bible18
Deficiency of miRNA-149-3p shaped gut microbiota and enhanced dextran sulfate sodium-induced colitis18
Paving the way to a new class of efficient and safe tuberculosis vaccines: The role of c-di-AMP in Mycobacterium tuberculosis immunity and virulence18
Trans-acting aptazyme for conditional gene knockdown in eukaryotic cells18
Targeting triple-negative breast cancer cells with a β1-integrin binding aptamer18
Thank you to our 2023 reviewers18
The Far Upstream Element Binding Protein 3 enhances HIV-1 transcriptional activity and regulates immune response pathways in T cells18
Thank you to our 2022 reviewers18
Engineering lentivirus envelope VSV-G for liver targeted delivery of IDOL-shRNA to ameliorate hypercholesterolemia and atherosclerosis18
Secreted PGK1 and IGFBP2 contribute to the bystander effect of miR-10b gene editing in glioma18
Shrimp miR-34 from Shrimp Stress Response to Virus Infection Suppresses Tumorigenesis of Breast Cancer17
Inhibition of microRNA-30a alleviates vascular remodeling in pulmonary arterial hypertension17
Integrated analysis of the rhesus monkey liver transcriptome during development and human primary HCC AFP-related gene expression17
SMTRI: A deep learning-based web service for predicting small molecules that target miRNA-mRNA interactions17
Protospacer modification improves base editing of a canonical splice site variant and recovery of CFTR function in human airway epithelial cells17
WITHDRAWN: AMPK-induced β-catenin degradation through Parkin phosphorylation reverses chemotherapy resistance of colon cancer cells17
hsa_circ_0001018 promotes papillary thyroid cancer by facilitating cell survival, invasion, G1/S cell cycle progression, and repressing cell apoptosis via crosstalk with miR-338-3p and SOX417
lncRNA FDNCR promotes apoptosis of granulosa cells by targeting the miR-543-3p/DCN/TGF-β signaling pathway in Hu sheep17
Estrogen-regulated miRs in bone enhance osteoblast differentiation and matrix mineralization17
Non-uniform dystrophin re-expression after CRISPR-mediated exon excision in the dystrophin/utrophin double-knockout mouse model of DMD17
Regulating PCCA gene expression by modulation of pseudoexon splicing patterns to rescue enzyme activity in propionic acidemia17
Improved cardiac-specific delivery of RAGE siRNA within small extracellular vesicles engineered to express intense cardiac targeting peptide attenuates myocarditis17
lncRNA Xist regulates sevoflurane-induced social and emotional impairment by modulating miR-98-5p/EDEM1 signaling axis in neonatal mice17
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