Experimental Hematology & Oncology

Papers
(The median citation count of Experimental Hematology & Oncology is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
A correlation of ineffective erythropoiesis and dysregulated signaling pathways in myelodysplastic syndromes/neoplasms267
Mitotic MTH1 inhibitor karonudib kills epithelial ovarian cancer independent of platinum sensitivity201
Inhibition of EYA family tyrosine phosphatase activity reveals a therapeutic vulnerability and enhances Menin and DOT1L inhibitor efficacy in KMT2A-rearranged leukemia167
The emerging scenario of immunotherapy for T-cell Acute Lymphoblastic Leukemia: advances, challenges and future perspectives161
Efficacy and safety of immune checkpoint inhibitors in metastatic penile squamous cell carcinoma: a retrospective multicenter analysis138
cGAS-ISG15-RAGE axis reprogram necroptotic microenvironment and promote lymphatic metastasis in head and neck cancer137
MENIN inhibitor-based therapy in acute leukemia: latest updates from the 2024 ASH annual meeting119
Cytokine-based models for efficient differentiation between infection and cytokine release syndrome in patients with hematological malignancies117
Fecal microbiota transplantation combined with ruxolitinib as a salvage treatment for intestinal steroid-refractory acute GVHD117
Targeting ST8SIA6-AS1 counteracts KRASG12C inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling112
Suppression of CYLD by HER3 confers ovarian cancer platinum resistance via inhibiting apoptosis and by inducing drug efflux99
Cardiotoxicity of small-molecule kinase inhibitors in cancer therapy97
Telomeres, telomerase, and cancer: mechanisms, biomarkers, and therapeutics94
Correction: The HSP90-MYC-CDK9 network drives therapeutic resistance in mantle cell lymphoma93
Tertiary lymphoid structures correlate with reduced recurrence risk and enhanced antitumor immunity in esophageal squamous cell carcinoma with pathologic non-complete response to neoadjuvant chemoimmu93
Prospective pharmacotyping of urothelial carcinoma organoids for drug sensitivity prediction – feasibility and real world experience91
From Amphiphiles to mRNA platforms: emerging vaccination strategies for pancreatic cancer88
Current approaches to develop “off-the-shelf” chimeric antigen receptor (CAR)-T cells for cancer treatment: a systematic review79
Next-generation sequencing for MRD monitoring in B-lineage malignancies: from bench to bedside76
New insights into epigenetic regulation of resistance to PD-1/PD-L1 blockade cancer immunotherapy: mechanisms and therapeutic opportunities74
HIV associated lymphoma: latest updates from 2023 ASH annual meeting71
Multi-omic profiling of the leukemic microenvironment shows bone marrow interstitial fluid is distinct from peripheral blood plasma70
Tetrahydromagnolol targets TRIM38 to mediate PANoptosis in cancer cells and has the potential for synergistic cancer therapy69
Enhanced cellular therapy: revolutionizing adoptive cellular therapy68
Exploiting E3 ubiquitin ligases to reeducate the tumor microenvironment for cancer therapy68
ISX–TWIST1 reprograms CD47–inflammasome signaling to reshape the immune microenvironment in liver cancer66
Emerging strategies in CAR-T cell therapy for acute myeloid leukemia: overcoming heterogeneity and improving safety through dual-antigen targeting64
Myeloid-derived suppressor cells in hematologic malignancies: two sides of the same coin61
Role of m6A writers, erasers and readers in cancer58
Emerging therapeutic frontiers in cancer: insights into posttranslational modifications of PD-1/PD-L1 and regulatory pathways58
Recent updates on central nervous system prophylaxis in patients with high-risk diffuse large B-cell lymphoma57
Correction: Unraveling the structures, functions and mechanisms of epithelial membrane protein family in human cancers54
All-in-one CRISPR/Cas-engineered glucocorticoid-receptor knock-out EBV-gp350-CAR knock-in T cells are potent and resistant to dexamethasone54
Correction: Breast cancer heterogeneity and its implication in personalized precision therapy54
Breast cancer heterogeneity and its implication in personalized precision therapy52
Tumor battlefield within inflamed, excluded or desert immune phenotypes: the mechanisms and strategies52
The novel retinoid WYC-209 sensitizes multiple myeloma to carfilzomib via epigenetically upregulating ZMYND851
Targeting hepcidin in colorectal cancer triggers a TNF-dependent-gasdermin E-driven immunogenic cell death response51
Three-dimensional chromatin landscapes in MLLr AML48
Phase II study of zevorcabtagene autoleucel, a fully human BCMA-targeting CAR T cell therapy, in patients with relapsed/refractory multiple myeloma48
Single-cell transcriptome analysis reveals stem cell-like subsets in the progression of Waldenström’s macroglobulinemia45
CAR-macrophages targets CD26 to eliminate chronic myeloid leukemia stem cells45
Hetrombopag plus porcine ATG and cyclosporine for the treatment of aplastic anaemia: early outcomes of a prospective pilot study45
TCR engineered T cells for solid tumor immunotherapy44
Novel agents and regimens in relapsed or refractory peripheral T-cell lymphoma: latest updates from 2023 ASH annual meeting43
Modified dendritic cell-derived exosomes activate both NK cells and T cells through the NKG2D/NKG2D-L pathway to kill CML cells with or without T315I mutation43
Matching-adjusted indirect comparison of efficacy and safety of lisocabtagene maraleucel and mosunetuzumab for the treatment of third-line or later relapsed or refractory follicular lymphoma42
CD19/CD22 CAR-T-cell cocktail therapy following autologous transplantation is an optimizing strategy for treating relapsed/refractory central nervous system lymphoma41
IL-39 promotes chronic graft-versus-host disease by increasing T and B Cell pathogenicity41
The natural FGF-trap long pentraxin 3 inhibits lymphangiogenesis and lymphatic dissemination40
Correction: Efficacy of NKG2D CAR-T cells with IL-15/IL-15Rα signaling for treating Epstein-Barr virus-associated lymphoproliferative disorder39
circRanGAP1/miR-27b-3p/NRAS Axis may promote the progression of hepatocellular Carcinoma39
Therapeutic activation of G protein-coupled estrogen receptor 1 in Waldenström Macroglobulinemia39
IPSS-M has greater survival predictive accuracy compared with IPSS-R in persons ≥ 60 years with myelodysplastic syndromes39
Metabolic drivers of genome instability in cancer: mechanisms and therapeutic opportunities38
Hepatitis B surface antigen: carcinogenesis mechanisms and clinical implications in hepatocellular carcinoma38
Matrix stiffness induces Ca2+-DCLK1-PIP5K1A mechanotransduction as a context-specific amplifier in pancreatic cancer progression and chemotherapy resistance38
Metabolic cross-talk within the bone marrow milieu: focus on multiple myeloma37
IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response36
Crosstalk between colorectal CSCs and immune cells in tumorigenesis, and strategies for targeting colorectal CSCs36
Vaccination with a combination of STING agonist-loaded lipid nanoparticles and CpG-ODNs protects against lung metastasis via the induction of CD11bhighCD27low memory-like NK cells36
The development and application of chimeric antigen receptor natural killer (CAR-NK) cells for cancer therapy: current state, challenges and emerging therapeutic advances36
Targeting NRF2 uncovered an intrinsic susceptibility of acute myeloid leukemia cells to ferroptosis36
Impact of diagnosis to treatment interval on outcomes in patients with newly diagnosed marginal zone lymphoma - a US multisite study36
Preclinical investigations and a first-in-human phase 1a trial of JS007, a novel anti-CTLA-4 antibody, in patients with advanced solid tumors35
The clinical impact of IKZF1 mutation in acute myeloid leukemia35
Construction of CD19 targeted dual- and enhanced dual-antibodies and their efficiency in the treatment of B cell malignancy35
Antibody-drug conjugates in breast cancer: current evidence and future directions34
A one-base therapeutic insertion in the HBG2 distal promoter reactivates γ-globin expression34
Targeting secretory autophagy in solid cancers: mechanisms, immune regulation and clinical insights33
KMT2A alterations in acute myeloid leukemia: a proposed genetic risk model and transplantation outcomes33
Chimeric antigen receptor-engineered NK cells: new weapons of cancer immunotherapy with great potential33
Versatile function of NF-ĸB in inflammation and cancer32
Recent advances and future perspectives in the therapeutics of prostate cancer32
Mechanistic insights and the clinical prospects of targeted therapies for glioblastoma: a comprehensive review32
Crosstalk between O-GlcNAcylation and ubiquitination: a novel strategy for overcoming cancer therapeutic resistance32
Immunotherapy in breast cancer: current landscape and emerging trends32
New exploration of KRASG12D inhibitors and the mechanisms of resistance31
Disparities in the incidence, mortality and disability-adjusted life years of 33 early-onset cancer groups globally, 2012–2021: a systematic analysis31
Immune-related gene index predicts metastasis for prostate cancer patients undergoing radical radiotherapy30
Preclinical activity of selinexor in combination with eribulin in uterine leiomyosarcoma29
Efficacy of NKG2D CAR-T cells with IL-15/IL-15Rα signaling for treating Epstein-Barr virus-associated lymphoproliferative disorder29
FGL1-mediated lymph node metastasis in stage T1 non-small cell lung cancer: therapeutic targeting29
Association between abnormal lipid profile and inflammation and progression of myelodysplastic syndrome to acute leukemia28
Whole-exome sequencing analysis identifies distinct mutational profile and novel prognostic biomarkers in primary gastrointestinal diffuse large B-cell lymphoma28
A novel AML1-ETO/FTO positive feedback loop promotes leukemogenesis and Ara-C resistance via stabilizing IGFBP2 in t(8;21) acute myeloid leukemia28
CRISPR/Cas9 technology for advancements in cancer immunotherapy: from uncovering regulatory mechanisms to therapeutic applications28
Combinatorial functionomics identifies HDAC6-dependent molecular vulnerability of radioresistant head and neck cancer28
Validation of a microRNA profile in urine liquid biopsy with diagnostic and stratification value for bladder cancer classification, available through the open app BladdermiRaCan27
Tunlametinib (HL-085) plus vemurafenib in patients with advanced BRAF V600-mutant solid tumors: an open-label, single-arm, multicenter, phase I study27
CD28 is superior to 4-1BB costimulation in generating CAR-NK cells for tumor immunotherapy27
Engineered extracellular vesicles displaying bi-specific T-cell engagers for targeted therapy of B-cell malignancies27
The CD64/CD28/CD3ζ chimeric receptor reprograms T-cell metabolism and promotes T-cell persistence and immune functions while triggering antibody-independent and antibody-dependent cytotoxicity27
Decoding the spatiotemporal characteristics of ferroptosis: reshaping tumour therapeutic strategies27
Downregulation of pro-surfactant protein B contributes to the recurrence of early-stage non-small cell lung cancer by activating PGK1-mediated Akt signaling27
Antitumor effect of a small-molecule inhibitor of KRASG12D in xenograft models of mucinous appendicular neoplasms27
Sarcosine sensitizes lung adenocarcinoma to chemotherapy by dual activation of ferroptosis via PDK4/PDHA1 signaling and NMDAR-mediated iron export26
DLC1 deficiency at diagnosis predicts poor prognosis in acute myeloid leukemia26
Venetoclax-based therapy for relapsed or refractory acute myeloid leukemia: latest updates from the 2022 ASH annual meeting26
Immunotherapy in chronic lymphocytic leukemia: advances and challenges26
The roles of tissue resident macrophages in health and cancer25
Obesity- and tumor-derived signals drive cancer-associated state transitions in breast mesenchymal stromal/stem cells reprogrammed by IL1RA or JAK inhibition25
Efficacy of melflufen in multiple myeloma with mutated or deleted TP5325
Incidence, mortality, and risk factors of bladder, kidney, prostate and testicular cancers in China and comparisons with the United States, the United Kingdom, Japan, and the Republic of Korea: an up-25
Single-cell analysis defines highly specific leukemia-induced neutrophils and links MMP8 expression to recruitment of tumor associated neutrophils during FGFR1 driven leukemogenesis24
Combination of percutaneous thermal ablation and adoptive Th9 cell transfer therapy against non-small cell lung cancer23
The role of pyroptosis and gasdermin family in tumor progression and immune microenvironment23
Correction to: Bispecific antibodies and dual-targeting CAR-T cells for multiple myeloma: latest updates from the 2023 ASCO annual meeting23
Molecular characterization of the CXCR4 / CXCR7 axis in germ cell tumors and its targetability using nanobody-drug-conjugates22
Advances in adoptive cellular immunotherapy and therapeutic breakthroughs in multiple myeloma22
Crosstalk between ferroptosis and extracellular vesicles in cancer: from interaction to clinical application22
Epigenetic and post-translational regulatory networks of ferroptosis in the tumor immune microenvironment22
Correction: New insights into epigenetic regulation of resistance to PD-1/PD-L1 blockade cancer immunotherapy: mechanisms and therapeutic opportunities21
In vivo CAR-T engineering: insights from the 2025 ASH annual meeting21
Adefovir dipivoxil inhibits APL progression through degradation of the oncoprotein PML-RARA21
Chinese expert consensus on Bruton tyrosine kinase inhibitors in the treatment of B-cell malignancies21
Bladder cancer subtypes exhibit limited plasticity across different microenvironments and in metastases21
Molecular background of Philadelphia chromosome dependent enhancement of cellular growth and tyrosine kinase inhibitor sensitivity21
Resolving intra-tumor heterogeneity and clonal evolution of core-binding factor acute myeloid leukemia patients with single-cell resolution21
An ureido-substituted benzenesulfonamide carbonic anhydrase inhibitor exerts a potent antitumor effect in vitro and in vivo20
Siltuximab for the treatment of early complications after chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia in children, adolescents, and young adults20
Molecular profiling of biliary tract cancers reveals distinct genomic landscapes between circulating and tissue tumor DNA20
Decoding leukemia at the single-cell level: clonal architecture, classification, microenvironment, and drug resistance20
Small cell lung cancer: emerging subtypes, signaling pathways, and therapeutic vulnerabilities20
Biomechanics in the tumor microenvironment: from biological functions to potential clinical applications20
ELK1 promotes the progress of myeloid leukemia by hindering the differentiation of neutrophils19
The progress of novel strategies on immune-based therapy in relapsed or refractory diffuse large B-cell lymphoma19
Chimeric antigen receptor-T cell therapy for T cell-derived hematological malignancies19
Engineered circular RNA-based DLL3-targeted CAR-T therapy for small cell lung cancer19
Lactylation modification in cancer: mechanisms, functions, and therapeutic strategies19
Long-term survival benefit of neoadjuvant oncolytic virus plus PD-1 blockade in acral melanoma: implications of STING in resistance and potential therapy19
Anti-tumor vaccine efficacy depends on adjuvant type and associates with induced IgG subclass and glycosylation profiles19
In-depth insight into tumor-infiltrating stromal cells linked to tertiary lymphoid structures and their prospective function in cancer immunotherapy19
Reduced morbidity and mortality of cGVHD in patients who received treatment with mesenchymal stromal cells for steroid-resistant aGVHD: long-term follow-up of a randomized phase 3 trial18
Inhibition of CDC20 potentiates anti-tumor immunity through facilitating GSDME-mediated pyroptosis in prostate cancer18
ZMIZ2 facilitates hepatocellular carcinoma progression via LEF1 mediated activation of Wnt/β-catenin pathway18
YAP-induced MAML1 cooperates with STAT3 to drive hepatocellular carcinoma progression18
Targeting TIM-3 for hematological malignancy: latest updates from the 2022 ASH annual meeting18
Preclinical and clinical studies on CAR-NK cell therapy: latest update from 2025 ASH Annual Meeting18
CDCA8 induced by NF-YA promotes hepatocellular carcinoma progression by regulating the MEK/ERK pathway18
The lncRNA PARylator promotes PARP1 activation and resistance to DNA‑damaging therapy in esophageal squamous cell carcinoma18
Global burden and trends of hematologic malignancies based on Global Cancer Observatory 2022 and Global Burden of Disease 202118
Improving CAR-T cell function through a targeted cytokine delivery system utilizing car target-modified extracellular vesicles18
Outcomes of allogeneic hematopoietic stem cell transplantation in R/R DLBCL patients with failure of CAR-T therapy18
TLR7/8 signaling activation enhances the potency of human pluripotent stem cell-derived eosinophils in cancer immunotherapy for solid tumors17
CRISPR/Cas9 system: recent applications in immuno-oncology and cancer immunotherapy17
Revealing the role of the gut microbiota in enhancing targeted therapy efficacy for lung adenocarcinoma17
Cirrhotic-extracellular matrix attenuates aPD-1 treatment response by initiating immunosuppressive neutrophil extracellular traps formation in hepatocellular carcinoma17
A cohort-based multi-omics identifies nuclear translocation of eIF5B /PD-L1/CD44 complex as the target to overcome Osimertinib resistance of ARID1A-deficient lung adenocarcinoma17
The role of organoids in cancer research17
CUL4B-DDB1-COP1-mediated UTX downregulation promotes colorectal cancer progression17
MMP14 from BM-MSCs facilitates progression and Ara-C resistance in acute myeloid leukemia via the JAK/STAT pathway17
Role of CDK4 as prognostic biomarker in Soft Tissue Sarcoma and synergistic effect of its inhibition in dedifferentiated liposarcoma sequential treatment16
The role of neutrophil extracellular traps in cancer progression, metastasis and therapy16
Outcome differences between PD-1/PD-L1 inhibitors-based monotherapy and combination treatments in NSCLC with brain metastases16
Bispecific antibodies as monotherapy or in combinations for non-hodgkin B-cell lymphoma: latest updates from the American society of hematology 2022 annual meeting16
EZH2 in hepatocellular carcinoma: progression, immunity, and potential targeting therapies16
Elevated expression of the RNA-binding protein IGF2BP1 enhances the mRNA stability of INHBA to promote the invasion and migration of esophageal squamous cancer cells16
A pan-cancer analysis of the oncogenic role of leucine zipper protein 2 in human cancer16
RNA binding proteins in MLL-rearranged leukemia16
Pan-cancer transcriptional atlas of minimal residual disease links DUSP1 to chemotherapy persistence16
Identification of adenoid subtype characterized with immune-escaped phenotype in lung squamous carcinoma based on transcriptomics16
The genomic analysis brings a new piece to the molecular jigsaw of idiopathic erythrocytosis16
Hypomethylating agents plus venetoclax for high-risk MDS and CMML as bridge therapy to transplant: a GESMD study16
Spatial ecostructural modelling of endometrial cancer identifies the key role of CD90 + CD105 + endothelial cells in tumour heterogeneity and predicts disease recurrence15
Next-generation immunotherapeutic approaches for blood cancers: Exploring the efficacy of CAR-T and cancer vaccines15
Applications of liposomes and lipid nanoparticles in cancer therapy: current advances and prospects15
Multidisciplinary recommendations for the management of CAR-T recipients in the post-COVID-19 pandemic era15
Comparison of local ablative therapies, including radiofrequency ablation, microwave ablation, stereotactic ablative radiotherapy, and particle radiotherapy, for inoperable hepatocellular carcinoma: a15
The influence of neuro-tumor interactions on tumorigenesis and therapeutic response15
Reconstructed colorectal cancer model to dissect the anti-tumor effect of mesenchymal stromal cells derived extracellular vesicles15
AOH1996 targets mitochondrial dynamics and metabolism in leukemic stem cells via mitochondrial PCNA inhibition15
Organoids for disease modeling and treatment: state-of-the-art15
Chimeric antigen receptor modified hematopoietic stem cells (CAR-HSCs) arm all immune forces for anti-tumor in mice14
Molecular correlation of response to pyrotinib in advanced NSCLC with HER2 mutation: biomarker analysis from two phase II trials14
TRIM family contribute to tumorigenesis, cancer development, and drug resistance14
Ubiquitin modification in the regulation of tumor immunotherapy resistance mechanisms and potential therapeutic targets14
Comprehensive antitumor immune response boosted by dual inhibition of SUMOylation and MEK in MYC-expressing KRAS-mutant cancers14
RHO GTPase family in hepatocellular carcinoma14
Extracellular matrix stiffness: mechanisms in tumor progression and therapeutic potential in cancer14
A bile-based microRNA signature for differentiating malignant from benign pancreaticobiliary disease14
Prospects and advances of PROTAC in the treatment of hematologic malignancies13
Pitavastatin is a novel Mcl-1 inhibitor that overcomes paclitaxel resistance in triple-negative breast cancer13
Roles of N6-methyladenosine (m6A) modifications in gynecologic cancers: mechanisms and therapeutic targeting13
Current insight into the regulation of PD-L1 in cancer13
CAR-T cell combination therapies in hematologic malignancies13
ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells13
Phase 2 trial of intravenous oncolytic virus JX-594 combined with low-dose cyclophosphamide in patients with advanced breast cancer13
Secretogranin II influences the assembly and function of MHC class I in melanoma13
Unravelling neutropenic enterocolitis: insights from gut microbiota, and intestinal barrier analyses13
GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment13
Surface TREM2 on circulating M-MDSCs as a novel prognostic factor for adults with treatment-naïve diffuse large B-cell lymphoma13
LINP1 represses unfolded protein response by directly inhibiting eIF2α phosphorylation to promote cutaneous squamous cell carcinoma13
Analysis of CD20 and PD-L1 levels on small extracellular vesicles (sEV) produced by DLBCL cells and EBV-transformed B cells, and potential role in T cell inhibition13
ANXA6/TRPV2 axis promotes lymphatic metastasis in head and neck squamous cell carcinoma by inducing autophagy13
Bruton tyrosine kinase inhibitors in B-cell lymphoma: beyond the antitumour effect12
Application patterns and outcomes of hematopoietic stem cell transplantation in peripheral T-cell lymphoma patients: a multicenter real-world study in China12
Radiation-induced exosomal miR-21 enhances tumor proliferation and invasiveness in breast cancer: implications for poor prognosis in radiotherapy patients12
Molecular profiling of skin cells identifies distinct cellular signatures in radiation-induced skin injury across various stages in the murine dataset12
Identification of a novel NPM1 mutation in acute myeloid leukemia12
Exploring coding and signal joints of novel TCR beta D-D rearrangements for tracking T-cell leukemia clonality12
The gut microbiota as a booster for radiotherapy: novel insights into radio-protection and radiation injury12
VISTA drives macrophages towards a pro-tumoral phenotype that promotes cancer cell phagocytosis yet down-regulates T cell responses12
Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition12
Recent advances and challenges of cellular immunotherapies in lung cancer treatment12
Multi-omics analyses of the heterogenous immune microenvironment in triple-negative breast cancer implicate UQCRFS1 potentiates tumor progression12
Mutation rates in main tumour driver genes predict prognosis in patients with superficial spreading or nodular primary melanoma: results from the CARAMEL study by the Italian Melanoma Intergroup (IMI)12
Transfer RNA-derived small RNA: an emerging small non-coding RNA with key roles in cancer12
Ferroptosis: a novel regulated cell death participating in cellular stress response, radiotherapy, and immunotherapy12
Vertical targeting of the PI3K/AKT pathway at multiple points is synergistic and effective for non-Hodgkin lymphoma12
RNA-based co-transfer of human CD8αβ with WT1-specific TCRαβ redirects tumor recognition by CD4 and γδ T-cells towards MHC class I-restricted WT1 epitopes and boosts CD8 T-cell responses with or witho12
Platelets in cancer and immunotherapy: functional dynamics and therapeutic opportunities12
Current advances and challenges in CAR T-Cell therapy for solid tumors: tumor-associated antigens and the tumor microenvironment12
Genetic factors, risk prediction and AI application of thrombotic diseases11
The clinical landscape of CAR NK cells11
Therapeutic targets of armored chimeric antigen receptor T cells navigating the tumor microenvironment11
CD7-directed CAR T-cell therapy: a potential immunotherapy strategy for relapsed/refractory acute myeloid leukemia11
Dual-targeted CAR T-cell immunotherapies for hematological malignancies: latest updates from the 2023 ASH annual meeting11
Infusion and delivery strategies to maximize the efficacy of CAR-T cell immunotherapy for cancers11
Novel cellular immunotherapies for hematological malignancies: recent updates from the 2021 ASH annual meeting11
Bisecting GlcNAc enhances CD8+ T cell-mediated killing of breast cancer by suppressing PD-L1 expression and its binding to PD-111
Inhibition of protein kinase CK2 remodels the tumor immune microenvironment and sensitizes lung cancer to PD-L1 blockade11
Thioredoxin-1 regulates self-renewal and differentiation of murine hematopoietic stem cells through p53 tumor suppressor11
Targeting metabolic reprogramming in chronic lymphocytic leukemia11
Natural killer cell-based cancer immunotherapy: from basics to clinical trials11
Single-cell profiling reveals FAM117A as a key regulator linking macrophage–epithelial crosstalk with the progression of lung adenocarcinoma11
Current and future therapies for follicular lymphoma11
Targeting NOTCH1 in combination with antimetabolite drugs prolongs life span in relapsed pediatric and adult T-acute lymphoblastic leukemia xenografts11
Targeting CD22 for B-cell hematologic malignancies11
Tumor-intrinsic PD-L1 drives lung cancer progression in response to TLR stimulation by promoting autophagy through the TRAF6–BECN1 signaling axis11
Prophylactic infusion of allogeneic double-negative T cells as immune modulators to prevent relapse in high-risk AML patients post-Allo-HSCT: a phase I trial11
p53 directly downregulates the expression of CDC20 to exert anti-tumor activity in mantle cell lymphoma11
Transforming cancer immunotherapy: integration of distinct immune-based approaches as redefined dual immunotherapy with potential third-sensitizer10
Developments in nanotechnology approaches for the treatment of solid tumors10
Overall survival of recurrent/metastatic head & neck squamous cell carcinoma patients progressing after ≥ 1 line of systemic therapy, treated with MVX-ONCO-1, a novel, first in class cell encapsul10
New approaches to idiopathic neutropenia in the era of clonal hematopoiesis10
Targeting collagen to optimize cancer immunotherapy10
New insight into circRNAs: characterization, strategies, and biomedical applications10
Targeting DNA helicase CMG complex and NFκB2-driven drug-resistant transcriptional axis to effectively treat KRASG12D-mutated pancreatic cancer10
CD105+CAF-derived exosomes CircAMPK1 promotes pancreatic cancer progression by activating autophagy10
Increasing cure rates of solid tumors by immune checkpoint inhibitors10
Distinct response to IL-1β blockade in liver- and lung-specific metastasis mouse models of pancreatic cancer with heterogeneous tumor microenvironments10
Addressing graft-versus-host disease in allogeneic cell-based immunotherapy for cancer10
CD47 antibody-armed oncolytic adenovirus promotes chimeric antigen receptor macrophage phagocytosis and antitumor immunity10
Myeloid-derived suppressor cells in cancer: therapeutic targets to overcome tumor immune evasion10
Bone marrow sympathetic neuropathy is a hallmark of hematopoietic malignancies and it involves severe ultrastructural damage9
Targeting platelet-tumor cell interactions via thromboxane A2-prostanoid receptor blockade to reduce metastasis in triple negative breast cancer9
The multi-CDK inhibitor dinaciclib reverses bromo- and extra-terminal domain (BET) inhibitor resistance in acute myeloid leukemia via inhibition of Wnt/β-catenin signaling9
ALKBH5 prevents hepatocellular carcinoma progression by post-transcriptional inhibition of PAQR4 in an m6A dependent manner9
Targeting the integrated stress response in hematologic malignancies9
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