OOIR: Observatory of International Research

Papers

(The median citation count of Bioengineered is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Statement of Retraction: Study on the molecular mechanism of nightshade in the treatment of colon cancer	192
Publisher’s Note	122
Publisher’s Note	101
Publisher’s Note	83
Statement of Retraction: Circular RNA CNOT2 knockdown regulates twist family BHLH transcription factor via targeting microRNA 409-3p to prevent breast cancer invasion, migration and epithelial–mesench	80
Photoregulation of the biosynthetic activity of fungus Inonotus obliquus using colloidal solutions of biogenic metal nanoparticles and low-intensity lase	76
Targeted insertion of heterogenous DNA using Cas9-gRNA ribonucleoprotein-mediated gene editing in Ganoderma lucidum	71
Phenolic amides (avenanthramides) in oats – an update review	70
Platinum-based adjuvant therapy was efficient for triple-negative breast cancer: a meta-analysis from randomized controlled trials	67
Approaches for neutrophil imaging: an important step in personalized medicine	50
Biodegradation of low, medium and high molecular weight phthalate by Gordonia sp. in a batch system: Kinetics and phytotoxicity analyses	45
Statement of Retraction: Next-generation -omics approaches to drive carboxylate production by acidogenic fermentation of food waste: a review	44
Statement of Retraction: Circular RNA SOX13 promotes malignant behavior and cisplatin resistance in non-small cell lung cancer through targeting microRNA-3194-3p/microtubule-associated protein RP/EB f	43
Statement of Retraction: MicroRNA-624-mediated ARRDC3/YAP/HIF1α axis enhances esophageal squamous cell carcinoma cell resistance to cisplatin and paclitaxel	42
Waste-derived volatile fatty acid production and ammonium removal from it by ion exchange process with natural zeolite	40
Advances in S gene targeted genome-editing and its applicability to disease resistance breeding in selected Solanaceae crop plants	38
RETRACTED ARTICLE: MiR-106a facilitates the sensorineural hearing loss induced by oxidative stress by targeting connexin-43	35
Tumor-infiltrating lymphocyte: features and prognosis of lymphocytes infiltration on colorectal cancer	30
Statement of Retraction: Methyltransferase-like 3 silenced inhibited the ferroptosis development via regulating the glutathione peroxidase 4 levels in the intracerebral hemorrhage progression	30
Statement of Retraction: CircSLC7A6 promotes the progression of Wilms’ tumor via microRNA-107/ ABL proto-oncogene 2 axis	28
Advances in oligosaccharides production from brown seaweeds: extraction, characterization, antimetabolic syndrome, and other potential applications	27
RETRACTED ARTICLE: MicroRNA-489-3p aggravates neuronal apoptosis and oxidative stress after cerebral ischemia-reperfusion injury	27
Statement of Retraction: Circular RNA hsa_circ_0000437 may be used as a new indicator for the diagnosis and prognosis of hepatocellular carcinoma	25
RETRACTED ARTICLE: Involvement of long non-coding RNA ZNF503 antisense RNA 1 in diabetic retinopathy and its possible underlying mechanism	24
Statement of Retraction: CircRNA hsa_circ_0070659 predicts poor prognosis and promotes non-small cell lung cancer (NSCLC) progression via microRNA-377 (miR-377) / Ras-Associated Binding Protein 3C (RA	24

Statement of Retraction: Interleukin-17A attenuates photoreceptor cell apoptosis in streptozotocin-induced diabetic mouse model	24
Statement of Retraction: Propofol inhibits oxidative stress injury through the glycogen synthase kinase 3 beta/nuclear factor erythroid 2-related factor 2/heme oxygenase-1 signaling pathway	23
Statement of Retraction: Graphene based scaffolds on bone tissue engineering	23
Statement of Retraction: Alpha-2 Heremans Schmid Glycoprotein (AHSG) promotes the proliferation of bladder cancer cells by regulating the TGF-β signalling pathway	22
A data-driven machine learning approach for discovering potent LasR inhibitors	22
Statement of Retraction: Preparation of a nanopearl powder/C-HA (chitosan-hyaluronic acid)/rhBMP-2 (recombinant human bone morphogenetic protein-2) composite artificial bone material and a preliminary	22
Role of ascomycete and basidiomycete fungi in meeting established and emerging sustainability opportunities: a review	22
Microplastics as an emerging contaminant of concern to our environment: a brief overview of the sources and implications	22
Statement of Retraction: Easy efficient HDR-based targeted knock-in in Saccharomyces cerevisiae genome using CRISPR-Cas9 system	21
Statement of Retraction: Extracellular vesicles derived from HBMSCs improved myocardial infarction through inhibiting zinc finger antisense 1 and activating Akt/Nrf2/HO-1 pathway	20
Statement of Retraction: Knockdown of Forkhead box protein P1 alleviates hypoxia reoxygenation injury in H9c2 cells through regulating Pik3ip1/Akt/eNOS and ROS/mPTP pathway	20
Exploring metal bioaccumulation ability of boreal white-rot fungi on fiberbank material	18
Databases for biomass and waste biorefinery – a mini-review and SWOT analysis	18
Statement of Retraction: lncNALT knockdown ameliorates hypertensive retinopathy via PTEN/PI3K/AKT pathway	17
RETRACTED ARTICLE: Neisseria sicca and Corynebacterium matruchotii inhibited oral squamous cell carcinomas	16
Statement of Retraction: MiR-106a facilitates the sensorineural hearing loss induced by oxidative stress by targeting connexin-43	16
Statement of Retraction: Geniposide promotes splenic Treg differentiation to alleviate colonic inflammation and intestinal barrier injury in ulcerative colitis mice	16
Engineering with Biomedical Sciences Changing the Horizon of Healthcare-A Review	16
RETRACTED ARTICLE: N(6)-methyladenosine-mediated miR-380-3p maturation and upregulation promotes cancer aggressiveness in pancreatic cancer	16
Statement of Retraction: Nesfatin-1 protects against diabetic cardiomyopathy in the streptozotocin-induced diabetic mouse model via the p38-MAPK pathway	16
Nanotechnology-assisted treatment of pharmaceuticals contaminated water	16
Statement of Retraction: Combination therapy with Nab-paclitaxel and the interleukin-15 fused with anti-human serum albumin nanobody as a synergistic treatment for colorectal cancer	15
Statement of Retraction: Long non-coding RNA DCST1-AS1/hsa-miR-582-5p/HMGB1 axis regulates colorectal cancer progression	15
RETRACTED ARTICLE: β‑aminoisobutyric acid ameliorates hypertensive vascular remodeling via activating the AMPK/SIRT1 pathway in VSMCs	15
Statement of Retraction: Homeodomain-containing gene 10 contributed to breast cancer malignant behaviors by activating Interleukin-6/Janus kinase 2/Signal transducer and activator of transcription 3 p	15
Statement of Retraction: The myocardial infarction-associated transcript 2 inhibits lipid accumulation and promotes cholesterol efflux in oxidized low-density lipoprotein-induced THP-1-derived macroph	14
Publisher’s Note	14
Controlled release fertilizer delivery system derived from rice straw cellulose nanofibres: a circular economy based solution for sustainable development	13
Statement of Retraction: Ibuprofen promotes p75 neurotrophin receptor expression through modifying promoter methylation and N6-methyladenosine-RNA-methylation in human gastric cancer cells	13
Aberrant expression of microRNA-4443 (miR-4443) in human diseases	13
RETRACTED ARTICLE: Isoginkgetin attenuates endoplasmic reticulum stress-induced autophagy of brain after ischemic reperfusion injury	13
Bacterial cellulose nanocrystal as drug delivery system for overcoming the biological barrier of cyano-phycocyanin: a biomedical application of microbial product	12
Statement of Retraction: Role of lncRNA LINC01194 in hepatocellular carcinoma via the miR-655-3p/SMAD family member 5 axis	12
Design, optimization, production and activity testing of recombinant immunotoxins expressed in plants and plant cells for the treatment of monocytic leukemia	12
Statement of Retraction: microRNA-10a-5p from gastric cancer cell-derived exosomes enhances viability and migration of human umbilical vein endothelial cells by targeting zinc finger MYND-type contain	12
Statement of Retraction: MicroRNA-489-3p aggravates neuronal apoptosis and oxidative stress after cerebral ischemia-reperfusion injury	12
Construction of a virtual reality platform for computer-aided navigation Lingnan bone setting technique	11
Sustainability of the anaerobic digestion of oil refinery secondary sludge	11
RETRACTED ARTICLE: Next-generation -omics approaches to drive carboxylate production by acidogenic fermentation of food waste: a review	11
Efficient remediation of antibiotic pollutants from the environment by innovative biochar: current updates and prospects	11
Assessing the effect of temperature drop on a stable anaerobic fermentation for volatile fatty acids production	11
Efficacy and safety of mycophenolate mofetil in the treatment of moderate to severe Graves’ orbitopathy: a meta-analysis	11
Expression of Concern: Platinum-based adjuvant therapy was efficient for triple-negative breast cancer: a meta-analysis from randomized controlled trials	11
Isolation of three different sizes of exosomes in an Asian population with different retinal diseases before and after treatment: preliminary results	11
A novel mannan-specific chimeric antigen receptor M-CAR redirects T cells to interact with Candida spp. hyphae and Rhizopus oryzae	10
Statement of Retraction: PSB0788 ameliorates maternal inflammation‐induced periventricular leukomalacia-like injury	10
RETRACTED ARTICLE: In vivo and in vitro studies of Alloimperatorin induced autophagy in cervical cancer cells via reactive oxygen species pathway	10
In vitro dynamic perfusion of prevascularized OECs-DBMs (outgrowth endothelial progenitor cell - demineralized bone matrix) complex fused to recipient vessels in an internal	10
Application of tissue engineering techniques in tracheal repair: a bibliometric study	10
RETRACTED ARTICLE: Circular RNA_0078767 upregulates Kruppel-like factor 9 expression by targeting microRNA-889, thereby inhibiting the progression of osteosarcoma	10

Enhanced growth and metabolite production from a novel strain of Porphyridium sp	10
RETRACTED ARTICLE: microRNA-301a-3p is a potential biomarker in venous ulcers vein and gets involved in endothelial cell dysfunction	10
RETRACTED ARTICLE: Alkannin reverses lipopolysaccharides-induced inflammatory responses by suppressing mitogen-activated protein kinase and nuclear factor kappa-B signalling	10
Statement of Retraction: Knockdown of small nucleolar RNA host gene 10 (SNHG10) alleviates the injury of human neuroblastoma cells via the miR-1277-5p/insulin substrate receptor 2 axis	10
Statement of Retraction: Long non-coding RNA lincRNA-erythroid prosurvival attenuates inflammation by enhancing myosin heavy chain 6 stability through recruitment of heterogeneous nuclear ribonucleopr	10
Statement of Retraction: Long non-coding RNA CCL2 promoted gastric cancer function via miR-128/ PARP2 signal pathway	9
Molecular characterization of SUT Gene Family in Solanaceae with emphasis on expression analysis of pepper genes during development and stresses	9
A perspective on methodologies and system boundaries to develop abatement cost for on-farm anaerobic digestion	9
Biogenic engineered zinc oxide nanoparticle for sulfur black dye removal from contaminated wastewater: comparative optimization, simulation modeling, and isotherms	9
Statement of Retraction: microRNA-301a-3p is a potential biomarker in venous ulcers vein and gets involved in endothelial cell dysfunction	9
Prodigiosin: a promising biomolecule with many potential biomedical applications	9
Statement of Retraction: Bone marrow mesenchymal stem cells combined with Atractylodes macrocephala polysaccharide attenuate ulcerative colitis	9
RETRACTED ARTICLE: MicroRNA-592 serves as a novel tumor suppressor in Uveal melanoma: bioinformatics analysis and in vitro cell function verification	9
Sustainable circular biorefinery approach for novel building blocks and bioenergy production from algae using microbial fuel cell	9
Statement of retraction: Somatostatin attenuates intestinal epithelial barrier injury during acute intestinal ischemia–reperfusion through Tollip/Myeloiddifferentiationfactor 88/Nuclear factor kappa-B	8
RETRACTED ARTICLE: MicroRNA miR-331-3p suppresses osteosarcoma progression via the Bcl-2/Bax and Wnt/β-Catenin signaling pathways and the epithelial-mesenchymal transition by targeting N-acetylglucosa	8
Enzymatic synthesis of Hydroxytyrosol from Oleuropein for valorization of an agricultural waste	8
Modified polymer membranes for the removal of pharmaceutical active compounds in wastewater and its mechanism-A review	8
Statement of Retraction: Protein tyrosine phosphatase receptor type Z1 inhibits the cisplatin resistance of ovarian cancer by regulating PI3K/AKT/mTOR signal pathway	8
Exploring the mechanisms of supplemented CO ₂ in enhancing methane production in anaerobic digestion process, a review	7
RETRACTED ARTICLE: SOCS5 contributes to temozolomide resistance in glioblastoma by regulating Bcl-2-mediated autophagy	7
Statement of Retraction: SOCS5 contributes to temozolomide resistance in glioblastoma by regulating Bcl-2-mediated autophagy	7
Statement of Retraction: Deciphering cell–cell interactions and communication in the tumor microenvironment and unraveling intratumoral genetic heterogeneity via single-cell genomic sequencing	7
IL-17A deletion reduces sevoflurane-induced neurocognitive impairment in neonatal mice by inhibiting NF-κB signaling pathway	7
RETRACTED ARTICLE: Easy efficient HDR-based targeted knock-in in Saccharomyces cerevisiae genome using CRISPR-Cas9 system	7
RETRACTED ARTICLE: MicroRNA-30c-2-3p represses malignant progression of gastric adenocarcinoma cells via targeting ARHGAP11A	7
Statement of Retraction: Long noncoding RNA UBA6-AS1 inhibits the malignancy of ovarian cancer cells via suppressing the decay of UBA6 mRNA	7
RETRACTED ARTICLE: Circular RNA hsa_circ_0000437 may be used as a new indicator for the diagnosis and prognosis of hepatocellular carcinoma	7
Comparative metabolomics analysis of pericarp from four varieties of Zanthoxylum bungeanum Maxim	7
RETRACTED ARTICLE: Long non-coding RNA LINC01270 is an onco-promotor in lung adenocarcinoma by upregulating LARP1 via sponging miR-326	7
Recent advances in microbial engineering approaches for wastewater treatment: a review	7
Statement of Retraction: N(6)-adenosine-methyltransferase-14 promotes glioma tumorigenesis by repressing argininosuccinate synthase 1 expression in an m6A-dependent manner	6
Thermochemical behavior of agricultural and industrial sugarcane residues for bioenergy applications	6
Current status and challenges in uterine myometrial tissue engineering	6
Statement of Retraction: Long non-coding RNA H19 aggravates keloid progression by upregulating SMAD family member 5 expression via miR-196b-5p	6
Potential of aerobic granular sludge membrane bioreactor (AGMBR) in wastewater treatment	6
Statement of Retraction: Long non-coding RNA-X-inactive specific transcript inhibits cell viability, and induces apoptosis through the microRNA-30c-5p/Bcl2-like protein 11 signaling axis in human gran	6
Statement of Retraction: Activation of cytotoxic T lymphocytes by self-differentiated myeloid-derived dendritic cells for killing breast cancer cells expressing folate receptor alpha protein	6
Statement of Retraction: Circular RNA Plasmacytoma Variant Translocation 1 (CircPVT1) knockdown ameliorates hypoxia-induced bladder fibrosis by regulating the miR-203/Suppressor of Cytokine Signaling	6
Genetically engineered IgG1 and nanobody oligomers acquire strong intrinsic CD40 agonism	5
Statement of Retraction: Dehydroevodiamine suppresses inflammatory responses in adjuvant-induced arthritis rats and human fibroblast-like synoviocytes	5
Performance of Malaysian kenaf Hibiscus cannabinus callus biomass and exopolysaccharide production in a novel liquid culture	5
Cutaneotrichosporon curvatum and Yarrowia lipolytica as key players for green chemistry: efficient oil producers from food waste via the carboxylate p	5
Statement of Retraction: Protein disulfide-isomerase A3 knockdown attenuates oxidized low-density lipoprotein-induced oxidative stress, inflammation and endothelial dysfunction in human umbilical vein	5
RETRACTED ARTICLE: Geniposide promotes splenic Treg differentiation to alleviate colonic inflammation and intestinal barrier injury in ulcerative colitis mice	5
RETRACTED ARTICLE: Deciphering cell–cell interactions and communication in the tumor microenvironment and unraveling intratumoral genetic heterogeneity via single-cell genomic sequencing	5
Diagnostic value of BinaxNOW antigen card for Severe Acute Respiratory Syndrome Coronavirus 2	5
Health effects of herbicides and its current removal strategies	4
Statement of Retraction: The LOXL1 antisense RNA 1 (LOXL1-AS1)/microRNA-423-5p (miR-423-5p)/ectodermal-neural cortex 1 (ENC1) axis promotes cervical cancer through the mitogen-activated protein kinase	4
Statement of Retraction: Isoginkgetin attenuates endoplasmic reticulum stress-induced autophagy of brain after ischemic reperfusion injury	4
Statement of Retraction	4
Impaired proliferation and migration of HUVEC and melanoma cells by human anti-FGF2 mAbs derived from a murine hybridoma by guided selection	4
Spent substrate from mushroom cultivation: exploitation potential toward various applications and value-added products	4
Statement of Retraction: LncRNA ASMTL-AS1/microRNA-1270 differentiate prognostic groups in gastric cancer and influence cell proliferation, migration and invasion	4
RETRACTED ARTICLE: Exosomes derived from Fibrinogen-like protein 1-overexpressing Bone Marrow-Derived Mesenchymal Stem Cells ameliorates rheumatoid arthritis	4
Effects of ischemic postconditioning and long non-coding RNAs in ischemic stroke	3
Large intestinal nutritional and physicochemical parameters from different dog sizes reshape canine microbiota structure and functions in vitro	3
Exploring biorefinery alternatives for biowaste valorization: a techno-economic assessment of enzymatic hydrolysis coupled with anaerobic digestion or solid-state fermentation for high-value bioproduc	3
Publisher’s Note	2
Statement of Retraction: Identification of a novel circular RNA circZNF652/miR-486-5p/SERPINE1 signaling cascade that regulates cancer aggressiveness in glioblastoma (GBM)	2
Statement of Retraction: Yin Yang 1 (YY1)-induced long intergenic non-protein coding RNA 472 (LINC00472) aggravates sepsis-associated cardiac dysfunction via the micro-RNA-335-3p (miR-335-3p)/Monoamin	2
Statement of Retraction: Upregulation of miR-140-5p uncouples mitochondria by targeting Bcl-xL in vascular smooth muscle cells in angiotensin II-induced hypertension	2
Extracellular vesicles in tumorigenesis, metastasis, chemotherapy resistance and intercellular communication in osteosarcoma	2
Statement of Retraction: F-box and WD repeat domain-containing 7 (FBXW7) mediates the hypoxia inducible factor-1α (HIF-1α)/vascular endothelial growth factor (VEGF) signaling pathway to affect hypoxic	2
Statement of Retraction: Potential roles of serum ATPase and AMPase in predicting diagnosis of colorectal cancer patients	1
Statement of Retraction: NLR family CARD domain containing 5 promotes hypoxia-induced cancer progress and carboplatin resistance by activating PI3K/AKT via carcinoembryonic antigen related cell adhesi	1
RETRACTED ARTICLE: WD repeat domain 62 (WDR62) promotes resistance of colorectal cancer to oxaliplatin through modulating mitogen-activated protein kinase (MAPK) signaling	1
Statement of Retraction: Neisseria sicca and Corynebacterium matruchotii inhibited oral squamous cell carcinomas by regulating genome stability	1
Statement of Retraction: Ephedrine alleviates middle cerebral artery occlusion-induced neurological deficits and hippocampal neuronal damage in rats by activating PI3K/AKT signaling pathway	1
Statement of Retraction: Metagenomics for taxonomy profiling: tools and approaches	1
Unlocking the biodegradative potential of native white-rot fungi: a comparative study of fiberbank organic pollutant mycoremediation	1
Statement of Retraction: miR-134-5p promotes inflammation and apoptosis of trophoblast cells via regulating FOXP2 transcription in gestational diabetes mellitus	1
Effects of bacterial inoculation on lignocellulose degradation and microbial properties during cow dung composting	1