OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Reports is 95. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Evasion of Type I Interferon by SARS-CoV-2	737
Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients	558
Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice	391
Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7	330
Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections	307
SARS-CoV-2 ORF3b Is a Potent Interferon Antagonist Whose Activity Is Increased by a Naturally Occurring Elongation Variant	307
MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells	280
Critical Role of Type III Interferon in Controlling SARS-CoV-2 Infection in Human Intestinal Epithelial Cells	268
LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants	264
D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction	251
Alzheimer’s Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation	222
Modulation of circRNA Metabolism by m6A Modification	216
Sex Differences in Gene Expression and Regulatory Networks across 29 Human Tissues	209
Structural and Biochemical Characterization of the nsp12-nsp7-nsp8 Core Polymerase Complex from SARS-CoV-2	209
Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes	205
Single-Nucleus RNA-Seq Is Not Suitable for Detection of Microglial Activation Genes in Humans	202
The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity	199
Meta-Analysis of the Alzheimer’s Disease Human Brain Transcriptome and Functional Dissection in Mouse Models	198
HCAR1/MCT1 Regulates Tumor Ferroptosis through the Lactate-Mediated AMPK-SCD1 Activity and Its Therapeutic Implications	193
A Single-Cell RNA Expression Map of Human Coronavirus Entry Factors	191
Furin Inhibitors Block SARS-CoV-2 Spike Protein Cleavage to Suppress Virus Production and Cytopathic Effects	191
Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth	187
Systematic functional analysis of SARS-CoV-2 proteins uncovers viral innate immune antagonists and remaining vulnerabilities	180
The effect of spike mutations on SARS-CoV-2 neutralization	177
Dynamic Shifts in the Composition of Resident and Recruited Macrophages Influence Tissue Remodeling in NASH	172

SARS-CoV-2 ORF9b inhibits RIG-I-MAVS antiviral signaling by interrupting K63-linked ubiquitination of NEMO	172
SARS-CoV-2 variant B.1.617 is resistant to bamlanivimab and evades antibodies induced by infection and vaccination	170
ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis	168
SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery	163
Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2	160
Patient-Derived Ovarian Cancer Organoids Mimic Clinical Response and Exhibit Heterogeneous Inter- and Intrapatient Drug Responses	159
BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils	158
Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant	157
Human gastrointestinal epithelia of the esophagus, stomach, and duodenum resolved at single-cell resolution	156
Cell-Type- and Brain-Region-Resolved Mouse Brain Lipidome	153
Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress	152
β-Glucan Induces Protective Trained Immunity against Mycobacterium tuberculosis Infection: A Key Role for IL-1	151
Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer	149
Acquisition and Adaptation of Ultra-small Parasitic Reduced Genome Bacteria to Mammalian Hosts	149
Systemic IL-15, IFN-γ, and IP-10/CXCL10 signature associated with effective immune response to SARS-CoV-2 in BNT162b2 mRNA vaccine recipients	145
Brain States and Transitions: Insights from Computational Neuroscience	144
Mn2+ Directly Activates cGAS and Structural Analysis Suggests Mn2+ Induces a Noncanonical Catalytic Synthesis of 2′3′-cGAMP	144
Atypical B cells are part of an alternative lineage of B cells that participates in responses to vaccination and infection in humans	143
ApoE4 Impairs Neuron-Astrocyte Coupling of Fatty Acid Metabolism	142
Predicting mRNA Abundance Directly from Genomic Sequence Using Deep Convolutional Neural Networks	141
Lactate Limits T Cell Proliferation via the NAD(H) Redox State	141
Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms	141
Nicotinamide Mononucleotide Supplementation Reverses the Declining Quality of Maternally Aged Oocytes	140
Human-IgG-Neutralizing Monoclonal Antibodies Block the SARS-CoV-2 Infection	138
An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain	138
Neurotoxic Reactive Astrocytes Drive Neuronal Death after Retinal Injury	137
METTL3 regulates viral m6A RNA modification and host cell innate immune responses during SARS-CoV-2 infection	137
Histones, DNA, and Citrullination Promote Neutrophil Extracellular Trap Inflammation by Regulating the Localization and Activation of TLR4	134
Neutrophils Obstructing Brain Capillaries Are a Major Cause of No-Reflow in Ischemic Stroke	133
Hypoxia Triggers the Intravasation of Clustered Circulating Tumor Cells	132
Macrophage Exosomes Resolve Atherosclerosis by Regulating Hematopoiesis and Inflammation via MicroRNA Cargo	130
Challenges in Establishing Pure Lung Cancer Organoids Limit Their Utility for Personalized Medicine	128
Cancer Stemness Meets Immunity: From Mechanism to Therapy	124
Most non-canonical proteins uniquely populate the proteome or immunopeptidome	122
Replicative senescence dictates the emergence of disease-associated microglia and contributes to Aβ pathology	121
Targeting TREM2 on tumor-associated macrophages enhances immunotherapy	121
Genome-wide Survey of Ribosome Collision	121
Linear epitope landscape of the SARS-CoV-2 Spike protein constructed from 1,051 COVID-19 patients	121
Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer	120
Induction of Human Trophoblast Stem Cells from Somatic Cells and Pluripotent Stem Cells	120
Gut microbiota-derived short-chain fatty acids regulate IL-17 production by mouse and human intestinal γδ T cells	118
Protein lactylation induced by neural excitation	118
TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity	118
PDK4 dictates metabolic resistance to ferroptosis by suppressing pyruvate oxidation and fatty acid synthesis	117
Potential Causes and Consequences of Gastrointestinal Disorders during a SARS-CoV-2 Infection	114
Anipose: A toolkit for robust markerless 3D pose estimation	113
Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery	112
Itaconate confers tolerance to late NLRP3 inflammasome activation	112
Endothelial Reprogramming by Disturbed Flow Revealed by Single-Cell RNA and Chromatin Accessibility Study	112
The SARS-CoV-2 Lambda variant exhibits enhanced infectivity and immune resistance	112

Cohesin-Dependent and -Independent Mechanisms Mediate Chromosomal Contacts between Promoters and Enhancers	107
Establishment of a reverse genetics system for SARS-CoV-2 using circular polymerase extension reaction	107
Homocysteine inhibits pro-insulin receptor cleavage and causes insulin resistance via protein cysteine-homocysteinylation	107
Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell	107
Enhancement versus neutralization by SARS-CoV-2 antibodies from a convalescent donor associates with distinct epitopes on the RBD	107
A single intranasal or intramuscular immunization with chimpanzee adenovirus-vectored SARS-CoV-2 vaccine protects against pneumonia in hamsters	106
Mechanical Stiffness Controls Dendritic Cell Metabolism and Function	106
Single-Cell Transcriptome Profiling Reveals β Cell Maturation in Stem Cell-Derived Islets after Transplantation	106
Small Molecule SARM1 Inhibitors Recapitulate the SARM1−/− Phenotype and Allow Recovery of a Metastable Pool of Axons Fated to Degenerate	104
Depletion of the AD Risk Gene SORL1 Selectively Impairs Neuronal Endosomal Traffic Independent of Amyloidogenic APP Processing	101
Structural and functional impact by SARS-CoV-2 Omicron spike mutations	101
Senescence, Necrosis, and Apoptosis Govern Circulating Cell-free DNA Release Kinetics	101
Cell-Type-Specific Gene Regulatory Networks Underlying Murine Neonatal Heart Regeneration at Single-Cell Resolution	100
Metabolic Modulation of Immunity: A New Concept in Cancer Immunotherapy	100
Distinct Populations of Immune-Suppressive Macrophages Differentiate from Monocytic Myeloid-Derived Suppressor Cells in Cancer	99
Dietary spermidine improves cognitive function	99
Cell-Type-Specific Immune Dysregulation in Severely Ill COVID-19 Patients	97
Combining spike- and nucleocapsid-based vaccines improves distal control of SARS-CoV-2	97
A compact vocabulary of paratope-epitope interactions enables predictability of antibody-antigen binding	97
Targeted delivery of CRISPR-Cas9 and transgenes enables complex immune cell engineering	96
Fractalkine-Dependent Microglial Pruning of Viable Oligodendrocyte Progenitor Cells Regulates Myelination	95