Cell Reports

Article	Citations
Leave no sister behind	350
Deneddylation of ribosomal proteins promotes synergy between MLN4924 and chemotherapy to elicit complete therapeutic responses	286
Combinatorial Developmental Controls on Striatonigral Circuits	254
Cdc48 influence on separase levels is independent of mitosis and suggests translational sensitivity of separase	234
Regulation of RNA localization during oocyte maturation by dynamic RNA-ER association and remodeling of the ER	229
An Aurora kinase A-BOD1L1-PP2A B56 axis promotes chromosome segregation fidelity	211
Gestationally dependent immune organization at the maternal-fetal interface	206
Cytoskeletal activation of NHE1 regulates mechanosensitive cell volume adaptation and proliferation	206
The OsbHLH002/OsICE1-OSH1 module orchestrates secondary cell wall formation in rice	204
Engineering of dendritic cell bispecific extracellular vesicles for tumor-targeting immunotherapy	189
Single-cell transcriptome profiling and chromatin accessibility reveal an exhausted regulatory CD4+ T cell subset in systemic lupus erythematosus	187
Distinct changes to hippocampal and medial entorhinal circuits emerge across the progression of cognitive deficits in epilepsy	166
The nuclear Argonaute HRDE-1 directs target gene re-localization and shuttles to nuage to promote small RNA-mediated inherited silencing	162
A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors	158
HSPA8 dampens SCAP/INSIG split and SREBP activation by reducing PKR-mediated INSIG phosphorylation	155
EWSR1 maintains centromere identity	153
Failure of digit tip regeneration in the absence of Lmx1b suggests Lmx1b functions disparate from dorsoventral polarity	152
Single-cell atlas of craniogenesis uncovers SOXC-dependent, highly proliferative, and myofibroblast-like osteodermal progenitors	146
The absence of telomerase leads to immune response and tumor regression in zebrafish melanoma	143
Pain hypersensitivity is dependent on autophagy protein Beclin 1 in males but not females	143
The histone chaperone ANP32B regulates chromatin incorporation of the atypical human histone variant macroH2A	139
Intercellular extrachromosomal DNA copy-number heterogeneity drives neuroblastoma cell state diversity	136
Development of pial collaterals by extension of pre-existing artery tips	136
Rigid, bivalent CTLA-4 binding to CD80 is required to disrupt the cis CD80/PD-L1 interaction	135
PCDH12 loss results in premature neuronal differentiation and impeded migration in a cortical organoid model	134

Axonal mRNA binding of hnRNP A/B is crucial for axon targeting and maturation of olfactory sensory neurons	132
Systematic analysis of human antibody response to ebolavirus glycoprotein shows high prevalence of neutralizing public clonotypes	132
Loss of neuronal heterogeneity in epileptogenic human tissue impairs network resilience to sudden changes in synchrony	131
Defects in CYB5A and CYB5B impact sterol-C4 oxidation in cholesterol biosynthesis and demonstrate regulatory roles of dimethyl sterols	131
A molecular pathway for cancer cachexia-induced muscle atrophy revealed at single-nucleus resolution	130
Long-lasting antibody B-cell responses to SARS-CoV-2 three years after the onset of the pandemic	126
Cellular Importin-α3 Expression Dynamics in the Lung Regulate Antiviral Response Pathways against Influenza A Virus Infection	120
Evaluating the impact of age on immune checkpoint therapy biomarkers	119
EZH2 inhibition mitigates HIV immune evasion, reduces reservoir formation, and promotes skewing of CD8+ T cells toward less-exhausted phenotypes	118
Endophytic mycobiont provides growth benefits via a phenylpropanoid-auxin axis in host plants	117
Single-cell RNA-seq analysis identifies the atlas of lymph fluid and reveals a sepsis-related T cell subset	117
The m C methyltransferase NSUN2 promotes progression of acute myeloid leukemia by regulating serine metabolism	117
Q&A with Bin Cao	115
Amino acids in cancer: Understanding metabolic plasticity and divergence for better therapeutic approaches	114
A type III-Dv CRISPR-Cas system is controlled by the transcription factor RpaB and interacts with the DEAD-box RNA helicase CrhR	113
Periostin deficiency reduces PD-1+ tumor-associated macrophage infiltration and enhances anti-PD-1 efficacy in colorectal cancer	112
Activity-dependent PI4P synthesis by PI4KIIIα regulates long-term synaptic potentiation	112
YTHDF2 suppresses the plasmablast genetic program and promotes germinal center formation	112
Laminar mechanisms of saccadic suppression in primate visual cortex	112
Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade	111
Enforced activation of the CREB/KDM2B axis prevents alcohol-induced embryonic developmental delay	108
Critical roles of the miR-17∼92 family in thymocyte development, leukemogenesis, and autoimmunity	108
OCIAD1 and prohibitins regulate the stability of the TIM23 protein translocase	106
Single-cell analysis reveals changes in BCG vaccine-injected mice modeling tuberculous meningitis brain infection	106
High plasticity of ribosomal DNA organization in budding yeast	105
Sugar-responsive inhibition of Myc-dependent ribosome biogenesis by Clockwork orange	104
Angiogenesis in the mature mouse cortex is governed in a regional- and Notch1-dependent manner	103
The medial entorhinal cortex encodes multisensory spatial information	103
The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1	102
DRD1 signaling modulates TrkB turnover and BDNF sensitivity in direct pathway striatal medium spiny neurons	102
Salmonella enterica serovar Typhimurium uses anaerobic respiration to overcome propionate-mediated colonization resistance	101
Structural basis for high-order complex of SARNP and DDX39B to facilitate mRNP assembly	101
Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV	101
Length-dependent poleward flux of sister kinetochore fibers promotes chromosome alignment	100
Motile cilia modulate neuronal and astroglial activity in the zebrafish larval brain	99
AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia	99
The T cell receptor sequence influences the likelihood of T cell memory formation	99
A conserved switch to less catalytically active Polycomb repressive complexes in non-dividing cells	98
Tyzzerella nexilis strains enriched in mobile genetic elements are involved in progressive multiple sclerosis	98
CPSF1 inhibition promotes widespread use of intergenic polyadenylation sites and impairs glycolysis in prostate cancer cells	97
Single cell approaches define neural stem cell niches and identify microglial ligands that can enhance precursor-mediated oligodendrogenesis	95
CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance	95
Santa-maria is a glial phagocytic receptor that acts with SIMU to recognize and engulf apoptotic neurons	95
Supercoiling-mediated feedback rapidly couples and tunes transcription	95
Neutralization fingerprinting technology for characterizing polyclonal antibody responses to dengue vaccines	94
Memory trace imbalance in reinforcement and punishment systems can reinforce implicit choices leading to obsessive-compulsive behavior	94
Actin-dependent astrocytic infiltration is a key step for axon defasciculation during remodeling	93
Atg15 is a vacuolar phospholipase that disintegrates organelle membranes	93
Genome-wide fetalization of enhancer architecture in heart disease	93
CD4+ T cells regulate sickness-induced anorexia and fat wasting during a chronic parasitic infection	92

Structure of a SARS-CoV-2 spike S2 subunit in a pre-fusion, open conformation	92
Exploring the pan-cancer landscape of posttranscriptional regulation	91
TGF-β Determines the Pro-migratory Potential of bFGF Signaling in Medulloblastoma	90
Compartmentalized PGRP expression along the dipteran Bactrocera dorsalis gut forms a zone of protection for symbiotic bacteria	89
Rhabdomyosarcoma fusion oncoprotein initially pioneers a neural signature in vivo	89
Fibroblast diversification is an embryonic process dependent on muscle contraction	89
FoxM1 coordinates cell division, protein synthesis, and mitochondrial activity in a subset of β cells during acute metabolic stress	89
Multimodal CRISPR screens uncover DDX39B as a global repressor of A-to-I RNA editing	89
β1 integrin signaling governs necroptosis via the chromatin-remodeling factor CHD4	88
In vivo partial cellular reprogramming enhances liver plasticity and regeneration	88
Identifying genetic determinants of Streptococcus pyogenes-host interactions in a murine intact skin infection model	88
Deep ancestry of Bornean hunter-gatherers supports long-term local ancestry dynamics	86
53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication	86
UQCRC1 engages cytochrome c for neuronal apoptotic cell death	86
An unconventional VH1-2 antibody tolerates escape mutations and shows an antigenic hotspot on SARS-CoV-2 spike	85
EKLF/Klf1 regulates erythroid transcription by its pioneering activity and selective control of RNA Pol II pause-release	85
MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis	85
Organization of Purkinje cell development by neuronal MEGF11 in cerebellar granule cells	84
A synaptic molecular dependency network in knockdown of autism- and schizophrenia-associated genes revealed by multiplexed imaging	83
Unique potential of immature adult-born neurons for the remodeling of CA3 spatial maps	83
SPT16 ubiquitylation by DCAF14-CRL4 regulates FACT binding to histones	83
Cell context-dependent CFI-1/ARID3 functions control neuronal terminal differentiation	82
A synthetic chlorophagy receptor promotes plant fitness by mediating chloroplast microautophagy	82
Acetylation-dependent regulation of BRAF oncogenic function	82
Chronic hypoxia stabilizes 3βHSD1 via autophagy suppression	82
A robot-rodent interaction arena with adjustable spatial complexity for ethologically relevant behavioral studies	82
Distinct TAM subset with cross-dressing capability determines the bifurcation of tumor immunity	82
FTY720 requires vitamin B12-TCN2-CD320 signaling in astrocytes to reduce disease in an animal model of multiple sclerosis	81
Chemical-induced epigenome resetting for regeneration program activation in human cells	81
Modulation of central synapse remodeling after remote peripheral injuries by the CCL2-CCR2 axis and microglia	81
Piezo1 senses hyphae and initiates host defense against pathogenic fungi	81
Oviduct epithelial cells constitute two developmentally distinct lineages that are spatially separated along the distal-proximal axis	81
A cell-type-specific alternative splicing regulator shapes synapse properties in a trans-synaptic manner	81
Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins	80
The balance between IFN-γ and ERK/MAPK signaling activities ensures lifelong maintenance of intestinal stem cells	80
Potentiation of cholinergic and corticofugal inputs to the lateral amygdala in threat learning	79
MOF-mediated acetylation of SIRT6 disrupts SIRT6-FOXA2 interaction and represses SIRT6 tumor-suppressive function by upregulating ZEB2 in NSCLC	79
Brain erythropoietin fine-tunes a counterbalance between neurodifferentiation and microglia in the adult hippocampus	79
Cortical mechanisms of visual brightness	79
Hierarchical behavioral analysis framework as a platform for standardized quantitative identification of behaviors	79
piRNA-guided intron removal from pre-mRNAs regulates density-dependent reproductive strategy	79
PRRC2B modulates oligodendrocyte progenitor cell development and myelination by stabilizing Sox2 mRNA	79
Coordinated expression of retained introns and poison exons in renal cell carcinoma	78
Phosphoproteomic profiling of influenza virus entry reveals infection-triggered filopodia induction counteracted by dynamic cortactin phosphorylation	78
Mitophagy antagonism by ZIKV reveals Ajuba as a regulator of PINK1 signaling, PKR-dependent inflammation, and viral invasion of tissues	78
HNF4A modulates glucocorticoid action in the liver	78
Mapping the evolution of T cell states during response and resistance to adoptive cellular therapy	77
Spatiotemporal patterns of neuronal subtype genesis suggest hierarchical development of retinal diversity	77
Multi-level functional genomics reveals molecular and cellular oncogenicity of patient-based 3′ untranslated region mutations	77
MYB68 regulates radial endodermal differentiation and suberin patterning	77
Prenatal inflammation perturbs murine fetal hematopoietic development and causes persistent changes to postnatal immunity	77
Direct type I interferon signaling in hepatocytes controls malaria	77
PIX is an N-terminal delivery domain that defines a class of polymorphic T6SS effectors in Enterobacterales	77
Stereotyped goal-directed manifold dynamics in the insular cortex	77
The structural basis of Salmonella A2B5 toxin neutralization by antibodies targeting the glycan-receptor binding subunits	76
A secondary metabolite of Limosilactobacillus reuteri R2lc drives strain-specific pathology in a spontaneous mouse model of multiple sclerosis	76
Food-induced dopamine signaling in AgRP neurons promotes feeding	76
The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression	76
Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP	75
Organization of hippocampal CA3 into correlated cell assemblies supports a stable spatial code	75
Association of B cell profile and receptor repertoire with the progression of Alzheimer’s disease	75
Chlorophyll biosynthesis under the control of arginine metabolism	75
A trans-kingdom T6SS RNase effector targeting both prokaryotic and host cells for pathogenesis	75
The architecture of silk-secreting organs during the final larval stage of silkworms revealed by single-nucleus and spatial transcriptomics	75
Mitochondrial cristae architecture protects against mtDNA release and inflammation	74
Regionally defined proteomic profiles of human cerebral tissue and organoids reveal conserved molecular modules of neurodevelopment	74
Modification of histidine repeat proteins by inorganic polyphosphate	74
Epitopes in the capsular polysaccharide and the porin OmpK36 receptors are required for bacteriophage infection of Klebsiella pneumoniae	74
Optogenetic silencing of medial septal GABAergic neurons disrupts grid cell spatial and temporal coding in the medial entorhinal cortex	74
Extracellular vesicle-mediated trafficking of molecular cues during human brain development	73
Cross-species communication via agr controls phage susceptibility in Staphylococcus aureus	73
Accumulation of branched-chain amino acids reprograms glucose metabolism in CD8+ T cells with enhanced effector function and anti-tumor response	73
Gamma synchronization between the medial temporal lobe and medial frontal cortex for goal-directed visual attention in humans	73
Control of Foxp3 induction and maintenance by sequential histone acetylation and DNA demethylation	73
Secretory IgA in breast milk protects against asthma through modulation of the gut microbiota	73
Direction selectivity of inhibitory interneurons in mouse barrel cortex differs between interneuron subtypes	73
Sugar detection in 3D: Structure of an insect gustatory receptor	72
HuR promotes triglyceride synthesis and intestinal fat absorption	72
The human placenta shapes the phenotype of decidual macrophages	72
PAMless SpRY exhibits a preference for the seed region for efficient targeting	72

LKB1 prevents ILC2 exhaustion to enhance antitumor immunity	72
PFKFB3 activates CAD to enhance de novo pyrimidine synthesis for cell growth	72
Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids	72
Mechanosensitive Notch-Dll4 and Klf2-Wnt9 signaling pathways intersect in guiding valvulogenesis in zebrafish	72
Auditory discrimination learning differentially modulates neural representation in auditory cortex subregions and inter-areal connectivity	71
Synaptic vesicle binding of α-synuclein is modulated by β- and γ-synucleins	71
Q&A with Hao Gu	71
SLC38A5 aggravates DC-mediated psoriasiform skin inflammation via potentiating lysosomal acidification	71
Mitochondrial fusion and cristae reorganization facilitate acquisition of cardiomyocyte identity during reprogramming of murine fibroblasts	71
Insulin and serine metabolism as sex-specific hallmarks of Alzheimer’s disease in the human hippocampus	71
Coupling to Pam16 differentially controls the dual role of Pam18 in protein import and respiratory chain formation	70
APOE4 drives inflammation in human astrocytes via TAGLN3 repression and NF-κB activation	70
SoxD genes are required for adult neural stem cell activation	69
PKM2 diverts glycolytic flux in dependence on mitochondrial one-carbon cycle	69
A cancer-associated METTL14 mutation induces aberrant m6A modification, affecting tumor growth	69
SRSF3-mediated regulation of N6-methyladenosine modification-related lncRNA ANRIL splicing promotes resistance of pancreatic cancer to gemcitabine	69
Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity	69
NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells	69
Tumor-derived Jagged1 promotes cancer progression through immune evasion	68
DNA replication is highly resilient and persistent under the challenge of mild replication stress	68
The CD27/CD70 pathway negatively regulates visceral adipose tissue-resident Th2 cells and controls metabolic homeostasis	68
An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma	68
Very-long-chain fatty acids are crucial to neuronal polarity by providing sphingolipids to lipid rafts	67
CD84 as a therapeutic target for breaking immune tolerance in triple-negative breast cancer	67
Structural basis of ligand specificity and channel activation in an insect gustatory receptor	67
Deficiency of the RNA-binding protein Cth2 extends yeast replicative lifespan by alleviating its repressive effects on mitochondrial function	66
Bone marrow monocytes sustain NK cell-poiesis during non-alcoholic steatohepatitis	66
Human antibodies in Mexico and Brazil neutralizing tick-borne flaviviruses	66
p120 RasGAP and ZO-2 are essential for Hippo signaling and tumor-suppressor function mediated by p190A RhoGAP	66
S1 represents multisensory contexts and somatotopic locations within and outside the bounds of the cortical homunculus	66
T-type Ca2+ and persistent Na+ currents synergistically elevate ventral, not dorsal, entorhinal cortical stellate cell excitability	66
Progenitor-like cells contributing to cellular heterogeneity in the nucleus pulposus are lost in intervertebral disc degeneration	66
Hippocampal and medial prefrontal ensemble spiking represents episodes and rules in similar task spaces	66
Autocleavage of separase suppresses its premature activation by promoting binding to cyclin B1	66
Documenting the diversity of the Namibian Ju|’hoansi intestinal microbiome	66
The C. elegans regulatory factor X (RFX) DAF-19M module: A shift from general ciliogenesis to cell-specific ciliary and behavioral specialization	65
T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells	65
Inhibition of PHLPP1/2 phosphatases rescues pancreatic β-cells in diabetes	65
Bioengineering for robust tolerance against cold and drought stresses via co-overexpressing three Cu-miRNAs in major food crops	64
The histone deacetylase HDAC1 controls dendritic cell development and anti-tumor immunity	64
Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription	64
Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways	64
Molecular, metabolic, and functional CD4 T cell paralysis in the lymph node impedes tumor control	63
Bodies in motion: Unraveling the distinct roles of motion and shape in dynamic body responses in the temporal cortex	63
CYLD deubiquitinates plakoglobin to promote Cx43 membrane targeting and gap junction assembly in the heart	63
The cellular basis of mechanosensation in mammalian tongue	63
Molecular landscape of sex- and modality-specific exercise adaptation in human skeletal muscle through large-scale multi-omics integration	63
A tug of war between DCC and ROBO1 signaling during commissural axon guidance	63
SYK ubiquitination by CBL E3 ligases restrains cross-presentation of dead cell-associated antigens by type 1 dendritic cells	63
Structural basis for ligand recognition of the human hydroxycarboxylic acid receptor HCAR3	63
Adaptation and genomic erosion in fragmented Pseudomonas aeruginosa populations in the sinuses of people with cystic fibrosis	62
Redefining sensorimotor mismatch selectivity in the visual cortex	62
Active APPL1 sequestration by Plasmodium favors liver-stage development	62
Dietary restriction induces a sexually dimorphic type I interferon response in mice with gene-environment interactions	62
Parallel processing in active dendrites during periods of intense spiking activity	62
Toward structural-omics of the bovine retinal pigment epithelium	62
Single-neuron models linking electrophysiology, morphology, and transcriptomics across cortical cell types	62
Antibody interference by a non-neutralizing antibody abrogates humoral protection against Plasmodium yoelii liver stage	62
Structural insights into anion selectivity and activation mechanism of LRRC8 volume-regulated anion channels	61
Dynamic chromatin remodeling in cycling human endometrium at single-cell level	61
Replication stress and defective checkpoints make fallopian tube epithelial cells putative drivers of high-grade serous ovarian cancer	61
Encoding of acquired sound-sequence salience by auditory cortical offset responses	61
PP2A licenses the FANCD2/FANCI complex for chromosome loading	61
Tel2 regulates redifferentiation of bipotential progenitor cells via Hhex during zebrafish liver regeneration	61
Mechanistic insight into the induction of liver tissue-resident memory CD8+ T cells by glycolipid-peptide vaccination	61
The Golgi-resident protein ACBD3 concentrates STING at ER-Golgi contact sites to drive export from the ER	60
Functional genome-wide short hairpin RNA library screening identifies key molecules for extracellular vesicle secretion from microglia	60
The Amot/integrin protein complex transmits mechanical forces required for vascular expansion	60
Gcn5- and Bre1-mediated Set2 degradation promotes chronological aging of Saccharomyces cerevisiae	60
Skin exposure to UVB light induces a skin-brain-gonad axis and sexual behavior	60
Blocking of ebolavirus spread through intercellular connections by an MPER-specific antibody depends on BST2/tetherin	60
Newly synthesized AIFM1 determines the hypersensitivity of T lymphocytes to STING activation-induced cell apoptosis	60
ERK1/2 interaction with DHPS regulates eIF5A deoxyhypusination independently of ERK kinase activity	60
G-protein-coupled receptor 84 regulates acute inflammation in normal and diabetic skin wounds	60
Structural insights into ligand recognition, selectivity, and activation of bombesin receptor subtype-3	59
Landscape and regulation of mRNA translation in the early C. elegans embryo	59
Targeting WEE1 in tumor-associated dendritic cells potentiates antitumor immunity via the cGAS/STING pathway	59
METTL14-dependent m6A modification controls iNKT cell development and function	59
SETDB1 promotes mammalian liver regeneration by stimulating cytokine CSF3 in hepatocytes	59
A ribosome-bound tRNA half stimulates mitochondrial translation during stress recovery in Trypanosoma brucei	59
The Chlamydia effector IncE employs two short linear motifs to reprogram host vesicle trafficking	58
Cd99l2 regulates excitatory synapse development and restrains immediate-early gene activation	58
Stromal cell and B cell dialogue potentiates IL-33-enriched lymphoid niches to support eosinophil recruitment and function during type 2 immunity	58
The soil microbiome modulates the sorghum root metabolome and cellular traits with a concomitant reduction of Striga infection	58
Cell-substrate distance fluctuations of confluent cells enable fast and coherent collective migration	58
Laminar and dorsoventral organization of layer 1 interneuronal microcircuitry in superficial layers of the medial entorhinal cortex	58
Downregulation of nutrition sensor GCN2 in macrophages contributes to poor wound healing in diabetes	58
EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks	57
Midbrain dopamine neurons signal phasic and ramping reward prediction error during goal-directed navigation	57
Critical contribution of 3′ non-seed base pairing to the in vivo function of the evolutionarily conserved let-7a microRNA	57
Transformation of an early-established motor circuit during maturation in zebrafish	57
C9ORF72 poly-PR induces TDP-43 nuclear condensation via NEAT1 and is modulated by HSP70 activity	57
The ADP-ribose hydrolase NUDT5 is important for DNA repair	57
Corticospinal neuron subpopulation-specific developmental genes prospectively indicate mature segmentally specific axon projection targeting	57
Identification of the viral and cellular microRNA interactomes during SARS-CoV-2 infection	57