Cell Reports

Article	Citations
Cellular Importin-α3 Expression Dynamics in the Lung Regulate Antiviral Response Pathways against Influenza A Virus Infection	366
Auditory discrimination learning differentially modulates neural representation in auditory cortex subregions and inter-areal connectivity	323
Q&A with Hao Gu	227
Structural basis for high-order complex of SARNP and DDX39B to facilitate mRNP assembly	219
FoxM1 coordinates cell division, protein synthesis, and mitochondrial activity in a subset of β cells during acute metabolic stress	182
LKB1 prevents ILC2 exhaustion to enhance antitumor immunity	179
Chemical-induced epigenome resetting for regeneration program activation in human cells	178
SoxD genes are required for adult neural stem cell activation	168
Mitochondrial fusion and cristae reorganization facilitate acquisition of cardiomyocyte identity during reprogramming of murine fibroblasts	163
Santa-maria is a glial phagocytic receptor that acts with SIMU to recognize and engulf apoptotic neurons	163
Tumor-derived Jagged1 promotes cancer progression through immune evasion	151
Motile cilia modulate neuronal and astroglial activity in the zebrafish larval brain	150
A synaptic molecular dependency network in knockdown of autism- and schizophrenia-associated genes revealed by multiplexed imaging	149
Deep ancestry of Bornean hunter-gatherers supports long-term local ancestry dynamics	148
Single cell approaches define neural stem cell niches and identify microglial ligands that can enhance precursor-mediated oligodendrogenesis	147
HuR promotes triglyceride synthesis and intestinal fat absorption	142
Organization of hippocampal CA3 into correlated cell assemblies supports a stable spatial code	137
Tyzzerella nexilis strains enriched in mobile genetic elements are involved in progressive multiple sclerosis	137
MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis	131
SPT16 ubiquitylation by DCAF14-CRL4 regulates FACT binding to histones	130
Cortical mechanisms of visual brightness	130
Insulin and serine metabolism as sex-specific hallmarks of Alzheimer’s disease in the human hippocampus	130
PCDH12 loss results in premature neuronal differentiation and impeded migration in a cortical organoid model	127
A vascular-associated fibroblastic cell controls pancreatic islet immunity	126
Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade	126

Secretory IgA in breast milk protects against asthma through modulation of the gut microbiota	124
Axonal mRNA binding of hnRNP A/B is crucial for axon targeting and maturation of olfactory sensory neurons	123
Q&A with Bin Cao	123
The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression	120
Single-cell RNA-seq analysis identifies the atlas of lymph fluid and reveals a sepsis-related T cell subset	119
A type III-Dv CRISPR-Cas system is controlled by the transcription factor RpaB and interacts with the DEAD-box RNA helicase CrhR	119
Systematic analysis of human antibody response to ebolavirus glycoprotein shows high prevalence of neutralizing public clonotypes	115
piRNA-guided intron removal from pre-mRNAs regulates density-dependent reproductive strategy	114
An unconventional VH1-2 antibody tolerates escape mutations and shows an antigenic hotspot on SARS-CoV-2 spike	114
Enforced activation of the CREB/KDM2B axis prevents alcohol-induced embryonic developmental delay	113
Deneddylation of ribosomal proteins promotes synergy between MLN4924 and chemotherapy to elicit complete therapeutic responses	113
Defects in CYB5A and CYB5B impact sterol-C4 oxidation in cholesterol biosynthesis and demonstrate regulatory roles of dimethyl sterols	112
PFKFB3 activates CAD to enhance de novo pyrimidine synthesis for cell growth	111
A robot-rodent interaction arena with adjustable spatial complexity for ethologically relevant behavioral studies	109
A trans-kingdom T6SS RNase effector targeting both prokaryotic and host cells for pathogenesis	109
Direction selectivity of inhibitory interneurons in mouse barrel cortex differs between interneuron subtypes	108
Critical roles of the miR-17∼92 family in thymocyte development, leukemogenesis, and autoimmunity	107
Potentiation of cholinergic and corticofugal inputs to the lateral amygdala in threat learning	106
Cell context-dependent CFI-1/ARID3 functions control neuronal terminal differentiation	104
Multi-level functional genomics reveals molecular and cellular oncogenicity of patient-based 3′ untranslated region mutations	103
Periostin deficiency reduces PD-1+ tumor-associated macrophage infiltration and enhances anti-PD-1 efficacy in colorectal cancer	103
Extracellular vesicle-mediated trafficking of molecular cues during human brain development	102
A synthetic chlorophagy receptor promotes plant fitness by mediating chloroplast microautophagy	101
Spatiotemporal patterns of neuronal subtype genesis suggest hierarchical development of retinal diversity	101
Long-lasting antibody B-cell responses to SARS-CoV-2 three years after the onset of the pandemic	101
Development of pial collaterals by extension of pre-existing artery tips	100
Cdc48 influence on separase levels is independent of mitosis and suggests translational sensitivity of separase	100
The absence of telomerase leads to immune response and tumor regression in zebrafish melanoma	99
The medial entorhinal cortex encodes multisensory spatial information	99
PKM2 diverts glycolytic flux in dependence on mitochondrial one-carbon cycle	99
The T cell receptor sequence influences the likelihood of T cell memory formation	98
Genome-wide fetalization of enhancer architecture in heart disease	97
Distinct changes to hippocampal and medial entorhinal circuits emerge across the progression of cognitive deficits in epilepsy	97
Laminar mechanisms of saccadic suppression in primate visual cortex	97
MYB68 regulates radial endodermal differentiation and suberin patterning	97
53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication	97
Failure of digit tip regeneration in the absence of Lmx1b suggests Lmx1b functions disparate from dorsoventral polarity	95
Fibroblast diversification is an embryonic process dependent on muscle contraction	94
CD4+ T cells regulate sickness-induced anorexia and fat wasting during a chronic parasitic infection	94
PIX is an N-terminal delivery domain that defines a class of polymorphic T6SS effectors in Enterobacterales	94
Identifying genetic determinants of Streptococcus pyogenes-host interactions in a murine intact skin infection model	93
Pain hypersensitivity is dependent on autophagy protein Beclin 1 in males but not females	93
High plasticity of ribosomal DNA organization in budding yeast	93
Stereotyped goal-directed manifold dynamics in the insular cortex	93
Neutralization fingerprinting technology for characterizing polyclonal antibody responses to dengue vaccines	92
Memory trace imbalance in reinforcement and punishment systems can reinforce implicit choices leading to obsessive-compulsive behavior	92
PRRC2B modulates oligodendrocyte progenitor cell development and myelination by stabilizing Sox2 mRNA	91
The CD27/CD70 pathway negatively regulates visceral adipose tissue-resident Th2 cells and controls metabolic homeostasis	90
EZH2 inhibition mitigates HIV immune evasion, reduces reservoir formation, and promotes skewing of CD8+ T cells toward less-exhausted phenotypes	90
CD84 as a therapeutic target for breaking immune tolerance in triple-negative breast cancer	90

Cross-species communication via agr controls phage susceptibility in Staphylococcus aureus	89
Genome restructuring and lineage diversification of Cryptococcus neoformans during chronic infection of human hosts	89
Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins	89
Coordinated expression of retained introns and poison exons in renal cell carcinoma	88
Distinct TAM subset with cross-dressing capability determines the bifurcation of tumor immunity	88
Organization of Purkinje cell development by neuronal MEGF11 in cerebellar granule cells	87
Regulation of RNA localization during oocyte maturation by dynamic RNA-ER association and remodeling of the ER	87
Loss of neuronal heterogeneity in epileptogenic human tissue impairs network resilience to sudden changes in synchrony	86
The OsbHLH002/OsICE1-OSH1 module orchestrates secondary cell wall formation in rice	85
Sugar-responsive inhibition of Myc-dependent ribosome biogenesis by Clockwork orange	85
Coupling to Pam16 differentially controls the dual role of Pam18 in protein import and respiratory chain formation	84
The human placenta shapes the phenotype of decidual macrophages	84
Combinatorial Developmental Controls on Striatonigral Circuits	84
Actin-dependent astrocytic infiltration is a key step for axon defasciculation during remodeling	84
A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors	84
Piezo1 senses hyphae and initiates host defense against pathogenic fungi	83
Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids	83
Phosphoproteomic profiling of influenza virus entry reveals infection-triggered filopodia induction counteracted by dynamic cortactin phosphorylation	82
A secondary metabolite of Limosilactobacillus reuteri R2lc drives strain-specific pathology in a spontaneous mouse model of multiple sclerosis	82
Activity-dependent PI4P synthesis by PI4KIIIα regulates long-term synaptic potentiation	82
Chronic hypoxia stabilizes 3βHSD1 via autophagy suppression	82
Regionally defined proteomic profiles of human cerebral tissue and organoids reveal conserved molecular modules of neurodevelopment	82
Chlorophyll biosynthesis under the control of arginine metabolism	81
FABP5 in skin macrophages mediates saturated fat-induced IL-1β signaling in psoriatic inflammation	81
Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV	80
CPSF1 inhibition promotes widespread use of intergenic polyadenylation sites and impairs glycolysis in prostate cancer cells	80
Gamma synchronization between the medial temporal lobe and medial frontal cortex for goal-directed visual attention in humans	79
Single-cell analysis reveals changes in BCG vaccine-injected mice modeling tuberculous meningitis brain infection	79
TGF-β Determines the Pro-migratory Potential of bFGF Signaling in Medulloblastoma	79
Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity	79
Compartmentalized PGRP expression along the dipteran Bactrocera dorsalis gut forms a zone of protection for symbiotic bacteria	79
Supercoiling-mediated feedback rapidly couples and tunes transcription	78
The histone chaperone ANP32B regulates chromatin incorporation of the atypical human histone variant macroH2A	78
DRD1 signaling modulates TrkB turnover and BDNF sensitivity in direct pathway striatal medium spiny neurons	78
EKLF/Klf1 regulates erythroid transcription by its pioneering activity and selective control of RNA Pol II pause-release	78
OCIAD1 and prohibitins regulate the stability of the TIM23 protein translocase	78
A cancer-associated METTL14 mutation induces aberrant m6A modification, affecting tumor growth	78
SLC38A5 aggravates DC-mediated psoriasiform skin inflammation via potentiating lysosomal acidification	77
Neuropeptide CRH prevents premature differentiation of OPCs following CNS injury and in early postnatal development	77
Rhabdomyosarcoma fusion oncoprotein initially pioneers a neural signature in vivo	77
Oncogenic Ras activation in permissive somatic cells triggers rapid-onset phenotypic plasticity and elicits a tumor-promoting neutrophil response	76
Energy status orchestrates YTHDF1 phase separation and tumorigenesis	76
Intravascular immune surveillance against viremia requires spatiotemporal coordination between Kupffer cells and ILC1s	75
Vascular Lamb1 guides the migration of retinal microglial precursors via Itga6-Rac1 signaling	75
Muscle spindles provide flexible sensory feedback for movement sequences	74
Retinal glia regulate development of the circadian photoentrainment circuit	74
Length-dependent poleward flux of sister kinetochore fibers promotes chromosome alignment	74
Genetic and chromatin regulation of Pvt1 monoallelic expression	74
YTHDF2 suppresses the plasmablast genetic program and promotes germinal center formation	73
Exploring the pan-cancer landscape of posttranscriptional regulation	73
Atg15 is a vacuolar phospholipase that disintegrates organelle membranes	73
The balance between IFN-γ and ERK/MAPK signaling activities ensures lifelong maintenance of intestinal stem cells	73
EWSR1 maintains centromere identity	73
Sugar detection in 3D: Structure of an insect gustatory receptor	72
AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia	72
Acetylation-dependent regulation of BRAF oncogenic function	72
Endophytic mycobiont provides growth benefits via a phenylpropanoid-auxin axis in host plants	72
HNF4A modulates glucocorticoid action in the liver	72
Unique potential of immature adult-born neurons for the remodeling of CA3 spatial maps	72
CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance	71
Angiogenesis in the mature mouse cortex is governed in a regional- and Notch1-dependent manner	71
Hierarchical behavioral analysis framework as a platform for standardized quantitative identification of behaviors	71
The architecture of silk-secreting organs during the final larval stage of silkworms revealed by single-nucleus and spatial transcriptomics	71
Epitopes in the capsular polysaccharide and the porin OmpK36 receptors are required for bacteriophage infection of Klebsiella pneumoniae	71
Intercellular extrachromosomal DNA copy-number heterogeneity drives neuroblastoma cell state diversity	70
A molecular pathway for cancer cachexia-induced muscle atrophy revealed at single-nucleus resolution	70
A cell-type-specific alternative splicing regulator shapes synapse properties in a trans-synaptic manner	70
Direct type I interferon signaling in hepatocytes controls malaria	69
MOF-mediated acetylation of SIRT6 disrupts SIRT6-FOXA2 interaction and represses SIRT6 tumor-suppressive function by upregulating ZEB2 in NSCLC	69
Control of Foxp3 induction and maintenance by sequential histone acetylation and DNA demethylation	69
The nuclear Argonaute HRDE-1 directs target gene re-localization and shuttles to nuage to promote small RNA-mediated inherited silencing	69
Salmonella enterica serovar Typhimurium uses anaerobic respiration to overcome propionate-mediated colonization resistance	69
Single-cell transcriptome profiling and chromatin accessibility reveal an exhausted regulatory CD4+ T cell subset in systemic lupus erythematosus	69
APOE4 drives inflammation in human astrocytes via TAGLN3 repression and NF-κB activation	68
Single-cell atlas of craniogenesis uncovers SOXC-dependent, highly proliferative, and myofibroblast-like osteodermal progenitors	68
In vivo partial cellular reprogramming enhances liver plasticity and regeneration	68
HSPA8 dampens SCAP/INSIG split and SREBP activation by reducing PKR-mediated INSIG phosphorylation	68
Structure of a SARS-CoV-2 spike S2 subunit in a pre-fusion, open conformation	68
Multimodal CRISPR screens uncover DDX39B as a global repressor of A-to-I RNA editing	68
An Aurora kinase A-BOD1L1-PP2A B56 axis promotes chromosome segregation fidelity	67

Structural basis of ligand specificity and channel activation in an insect gustatory receptor	67
FTY720 requires vitamin B12-TCN2-CD320 signaling in astrocytes to reduce disease in an animal model of multiple sclerosis	67
Prenatal inflammation perturbs murine fetal hematopoietic development and causes persistent changes to postnatal immunity	66
Cytoskeletal activation of NHE1 regulates mechanosensitive cell volume adaptation and proliferation	66
Amino acids in cancer: Understanding metabolic plasticity and divergence for better therapeutic approaches	66
PAMless SpRY exhibits a preference for the seed region for efficient targeting	66
Modulation of central synapse remodeling after remote peripheral injuries by the CCL2-CCR2 axis and microglia	66
Engineering of dendritic cell bispecific extracellular vesicles for tumor-targeting immunotherapy	66
A conserved switch to less catalytically active Polycomb repressive complexes in non-dividing cells	66
Progenitor-like cells contributing to cellular heterogeneity in the nucleus pulposus are lost in intervertebral disc degeneration	66
An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma	65
Synaptic vesicle binding of α-synuclein is modulated by β- and γ-synucleins	65
Food-induced dopamine signaling in AgRP neurons promotes feeding	65
β1 integrin signaling governs necroptosis via the chromatin-remodeling factor CHD4	65
SRSF3-mediated regulation of N6-methyladenosine modification-related lncRNA ANRIL splicing promotes resistance of pancreatic cancer to gemcitabine	64
Gestationally dependent immune organization at the maternal-fetal interface	64
Optogenetic silencing of medial septal GABAergic neurons disrupts grid cell spatial and temporal coding in the medial entorhinal cortex	64
DNA replication is highly resilient and persistent under the challenge of mild replication stress	64
Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP	64
Modification of histidine repeat proteins by inorganic polyphosphate	64
Mitochondrial cristae architecture protects against mtDNA release and inflammation	64
Rigid, bivalent CTLA-4 binding to CD80 is required to disrupt the cis CD80/PD-L1 interaction	63
The m C methyltransferase NSUN2 promotes progression of acute myeloid leukemia by regulating serine metabolism	63
Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages	63
Association of B cell profile and receptor repertoire with the progression of Alzheimer’s disease	63
Very-long-chain fatty acids are crucial to neuronal polarity by providing sphingolipids to lipid rafts	63
Documenting the diversity of the Namibian Ju|’hoansi intestinal microbiome	63
Accumulation of branched-chain amino acids reprograms glucose metabolism in CD8+ T cells with enhanced effector function and anti-tumor response	63
Metabolite-dependent m6A methylation driven by mechanotransduction-metabolism-epitranscriptomics axis promotes bone development and regeneration	63
Optogenetic activation of cortical microglia promotes neuronal activity and pain hypersensitivity	63
Hippocampal and medial prefrontal ensemble spiking represents episodes and rules in similar task spaces	62
METTL3 regulates cartilage development and homeostasis by affecting Lats1 mRNA stability in an m6A-YTHDF2-dependent manner	62
Multimode neural population coding of diverse innate fear response by mitral and tufted cells	62
Human antibodies in Mexico and Brazil neutralizing tick-borne flaviviruses	62
SETDB1 promotes mammalian liver regeneration by stimulating cytokine CSF3 in hepatocytes	61
Structural insights into anion selectivity and activation mechanism of LRRC8 volume-regulated anion channels	61
LINC00921 reduces lung cancer radiosensitivity by destabilizing NUDT21 and driving aberrant MED23 alternative polyadenylation	61
ERK1/2 interaction with DHPS regulates eIF5A deoxyhypusination independently of ERK kinase activity	61
A regulatory module tunes OsYABBY4 expression to modify vascular bundle development and tillering in rice	61
Tel2 regulates redifferentiation of bipotential progenitor cells via Hhex during zebrafish liver regeneration	61
Cd99l2 regulates excitatory synapse development and restrains immediate-early gene activation	61
A ribosome-bound tRNA half stimulates mitochondrial translation during stress recovery in Trypanosoma brucei	61
RETRACTED: ASCL1 is activated downstream of the ROR2/CREB signaling pathway to support lineage plasticity in prostate cancer	61
Probing the functional constraints of influenza A virus NEP by deep mutational scanning	60
Septo-subicular cholinergic circuit promotes seizure development via astrocytic inflammation	60
NKp44/HLA-DP-dependent regulation of CD8 effector T cells by NK cells	60
The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels	60
Identification of the viral and cellular microRNA interactomes during SARS-CoV-2 infection	60
Chromatin modification abnormalities by CHD7 and KMT2C loss promote medulloblastoma progression	60
Pak2-mediated phosphorylation promotes RORγt ubiquitination and inhibits colonic inflammation	59
Bodies in motion: Unraveling the distinct roles of motion and shape in dynamic body responses in the temporal cortex	59
Mitochondrial transplantation rescues Ca2+ homeostasis imbalance and myocardial hypertrophy in SLC25A3-related hypertrophic cardiomyopathy	59
GM-CSF production by non-classical monocytes controls antagonistic LPS-driven functions in allergic inflammation	59
Subcellular localization shapes the fate of RNA polymerase III	59
The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity	58
Molecular landscape of sex- and modality-specific exercise adaptation in human skeletal muscle through large-scale multi-omics integration	58
Laminar and dorsoventral organization of layer 1 interneuronal microcircuitry in superficial layers of the medial entorhinal cortex	58
Dietary restriction induces a sexually dimorphic type I interferon response in mice with gene-environment interactions	58
Phospholipids can regulate complex I assembly independent of their role in maintaining mitochondrial membrane integrity	58
Stromal cell and B cell dialogue potentiates IL-33-enriched lymphoid niches to support eosinophil recruitment and function during type 2 immunity	58
Antibodies against the Ebola virus soluble glycoprotein are associated with long-term vaccine-mediated protection of non-human primates	58
Identification and characterization of NFATc1+ skeletal stem cells in bone regeneration	58
Two-step fitness selection for intra-host variations in SARS-CoV-2	57
The predatory soil bacterium Myxococcus xanthus combines a Tad- and an atypical type 3-like protein secretion system to kill bacterial cells	57
The Golgi-resident protein ACBD3 concentrates STING at ER-Golgi contact sites to drive export from the ER	57
Parallel processing in active dendrites during periods of intense spiking activity	57
The mitotic ATR-Chk1 pathway promotes CDK1 activity for faithful chromosome segregation	57
Molecular, metabolic, and functional CD4 T cell paralysis in the lymph node impedes tumor control	57
Blocking of ebolavirus spread through intercellular connections by an MPER-specific antibody depends on BST2/tetherin	57
Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice	57
Metabolic reprogramming by histone deacetylase inhibition preferentially targets NRF2-activated tumors	57
The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement	57
Replication stress and defective checkpoints make fallopian tube epithelial cells putative drivers of high-grade serous ovarian cancer	57
Redefining sensorimotor mismatch selectivity in the visual cortex	57
Structural basis for ligand recognition of the human hydroxycarboxylic acid receptor HCAR3	56
Identification of CNOT1-CCR4-NOT as a suppressor of 53BP1-p53-p21 signaling	56
Comparing neoantigen cancer vaccines and immune checkpoint therapy unveils an effective vaccine and anti-TREM2 macrophage-targeting dual therapy	56
A tug of war between DCC and ROBO1 signaling during commissural axon guidance	56
Bordetella spp. block eosinophil recruitment to suppress the generation of early mucosal protection	56
Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways	56
Highly mutated antibodies capable of neutralizing N276 glycan-deficient HIV after a single immunization with an Env trimer	56
Multi-omic profiling reveals the ataxia protein sacsin is required for integrin trafficking and synaptic organization	56
Transformation of an early-established motor circuit during maturation in zebrafish	56
p120 RasGAP and ZO-2 are essential for Hippo signaling and tumor-suppressor function mediated by p190A RhoGAP	56
Automated live-cell single-molecule tracking in enteroid monolayers reveals transcription factor dynamics probing lineage-determining function	56
Histone acetyltransferase HAF2 associates with pyruvate dehydrogenase complex to control H3K14ac and H3K23ac in ethylene response	56
Toward structural-omics of the bovine retinal pigment epithelium	56
The Chlamydia effector IncE employs two short linear motifs to reprogram host vesicle trafficking	56
Modulation function of sphingomyelin molecular species in TLR4 signaling and cell death	56
Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination	56
Nucleus accumbens local circuit for cue-dependent aversive learning	56
Human cytomegalovirus forms phase-separated compartments at viral genomes to facilitate viral replication	55
Deep repertoire mining uncovers ultra-broad coronavirus neutralizing antibodies targeting multiple spike epitopes	55
Age-dependent glial heterogeneity and traumatic injury responses in a vertebrate brain structure	55
The ADP-ribose hydrolase NUDT5 is important for DNA repair	55