Cellular Oncology

Article	Citations
HNRNPH1 stabilizes FLOT2 mRNA in a non-canonical m6A-dependent manner to promote malignant progression in nasopharyngeal carcinoma	108
The therapeutic potential of exosomes in lung cancer	93
Publisher Correction to: RAB37 suppresses the EMT, migration and invasion of gastric cancer cells by mediating autophagic degradation of β-catenin	82
Dissecting the single-cell transcriptome network of macrophage and identifies a signature to predict prognosis in lung adenocarcinoma	80
Methionine-producing tumor micro(be) environment fuels growth of solid tumors	66
Asymmetric post-translational modifications regulate the nuclear translocation of STAT3 homodimers in response to leukemia inhibitory factor	66
Pathways and outputs orchestrated in tumor microenvironment cells by hypoxia-induced tumor-derived exosomes in pan-cancer	61
Molecular mechanisms underlying the action of carcinogens in gastric cancer with a glimpse into targeted therapy	60
CoQ10 reduces glioblastoma growth and infiltration through proteome remodeling and inhibition of angiogenesis and inflammation	57
Deciphering the molecular landscape: evolutionary progression from gynecomastia to aggressive male breast cancer	51
RETRACTED ARTICLE: The autocrine glycosylated-GREM1 interacts with TGFB1 to suppress TGFβ/BMP/SMAD-mediated EMT partially by inhibiting MYL9 transactivation in urinary carcinoma	50
Neuregulin-induced HER3 activation drives migration in head and neck squamous cell carcinoma via HER2 and FAK signaling pathways	49
In vivo study revealed pro-tumorigenic effect of CMTM3 in hepatocellular carcinoma involving the regulation of peroxisome proliferator-activated receptor gamma (PPARγ)	46
Targeting nucleolin improves sensitivity to chemotherapy in acute lymphoblastic leukemia	46
Loss of histone deubiquitinase Bap1 triggers anti-tumor immunity	39
OSW-1 induces apoptosis and cyto-protective autophagy, and synergizes with chemotherapy on triple negative breast cancer metastasis	36
High-plex spatial transcriptomic profiling reveals distinct immune components and the HLA class I/DNMT3A/CD8 modulatory axis in mismatch repair-deficient endometrial cancer	36
Ubiquilin-4 induces immune escape in gastric cancer by activating the notch signaling pathway	35
TRPV4 drives the progression of leiomyosarcoma by promoting ECM1 generation and co-activating the FAK/PI3K/AKT/GSK3β pathway	33
Trends in immunotherapy for oral squamous cell carcinoma	32
RAB37 suppresses the EMT, migration and invasion of gastric cancer cells by mediating autophagic degradation of β-catenin	31
SUMOylation inhibitors activate anti-tumor immunity by reshaping the immune microenvironment in a preclinical model of hepatocellular carcinoma	31
Proteomic characterisation of prostate cancer intercellular communication reveals cell type-selective signalling and TMSB4X-dependent fibroblast reprogramming	30
Exploring the impact of PDGFD in osteosarcoma metastasis through single-cell sequencing analysis	30
FSCN1 induced PTPRF-dependent tumor microenvironment inflammatory reprogramming promotes lung adenocarcinoma progression via regulating macrophagic glycolysis	29

Dual anti-angiogenic and anti-metastatic activity of myriocin synergistically enhances the anti-tumor activity of cisplatin	28
OrganoIDNet: a deep learning tool for identification of therapeutic effects in PDAC organoid-PBMC co-cultures from time-resolved imaging data	28
Next-generation BCMA-targeted chimeric antigen receptor CARTemis-1: the impact of manufacturing procedure on CAR T-cell features	28
Ezrin accelerates breast cancer liver metastasis through promoting furin-like convertase-mediated cleavage of Notch1	27
Modulation of miR-146b by N6-methyladenosine modification remodels tumor-associated macrophages and enhances anti-PD-1 therapy in colorectal cancer	27
Correction to: 3D bioprinted tumor model: a prompt and convenient platform for overcoming immunotherapy resistance by recapitulating the tumor microenvironment	27
TBX21 attenuates colorectal cancer progression via an ARHGAP29/RSK/GSK3β dependent manner	26
RRM2 as a novel prognostic and therapeutic target of NF1-associated MPNST	26
Aberrant expression of circular RNA DHPR facilitates tumor growth and metastasis by regulating the RASGEF1B/RAS/MAPK axis in hepatocellular carcinoma	26
Silencing AHNAK promotes nasopharyngeal carcinoma progression by upregulating the ANXA2 protein	26
Dipyridamole enhances the anti-cancer ability of aspirin against colorectal cancer by inducing apoptosis in an unfolded protein response-dependent manner	25
From basic research to clinical application: targeting fibroblast activation protein for cancer diagnosis and treatment	24
Neuropilin-2 acts a critical determinant for epithelial-to-mesenchymal transition and aggressive behaviors of human head and neck cancer	24
Exosomes: a potential diagnostic and treatment modality in the quest for counteracting cancer	24
USP28 promotes tumor progression and glycolysis by stabilizing PKM2/Hif1-α in cholangiocarcinoma	24
The survival prediction analysis and preliminary study of the biological function of YEATS2 in hepatocellular carcinoma	24
TRIM28 promotes tumor growth and metastasis in breast cancer by targeting the BRD7 protein for ubiquitination and degradation	24
Emerging roles of deubiquitinating enzymes in actin cytoskeleton and tumor metastasis	24
Cancer/testis-45A1 promotes cervical cancer cell tumorigenesis and drug resistance by activating oncogenic SRC and downstream signaling pathways	23
Feature-weight based measurement of cancerous transcriptome using cohort-wide and sample-specific information	23
Prognostic significance of collagen signatures at breast tumor boundary obtained by combining multiphoton imaging and imaging analysis	23
Lactylation: the regulatory code of cellular life activity and a barometer of diseases	22
Osteopontin secreted from obese adipocytes enhances angiogenesis and promotes progression of pancreatic ductal adenocarcinoma in obesity	22
The PPP2R1A cancer hotspot mutant p.R183W increases clofarabine resistance in uterine serous carcinoma cells by a gain-of-function mechanism	22
The composition and roles of gastric stem cells in epithelial homeostasis, regeneration, and tumorigenesis	21
Extracellular vesicles related gene HSPH1 exerts anti-tumor effects in prostate cancer via promoting the stress response of CD8 + T cells	21
Iron metabolism in colorectal cancer: a balancing act	21
Integrated analysis of single-cell RNA-seq and bulk RNA-seq reveals immune suppression subtypes and establishes a novel signature for determining the prognosis in lung adenocarcinoma	21
Small extracellular vesicles promote invadopodia activity in glioblastoma cells in a therapy-dependent manner	21
Targeting CSPG4 enhances the anti-tumor activity of CAR-NK cells for glioblastoma	21
Targeting MEK/COX-2 axis improve immunotherapy efficacy in dMMR colorectal cancer with PIK3CA overexpression	21
Lenalidomide overcomes the resistance to third-generation CD19-CAR-T cell therapy in preclinical models of diffuse large B-cell lymphoma	20
Targeting the Notch-Furin axis with 2-hydroxyoleic acid: a key mechanism in glioblastoma therapy	20
Non-coding RNA regulation of integrins and their potential as therapeutic targets in cancer	20
HDAC6: A unique HDAC family member as a cancer target	20
Retraction Note: TRAIL enhances quinacrine-mediated apoptosis in breast cancer cells through induction of autophagy via modulation of p21 and DR5 interactions	20
Integrating multi-modal transcriptomics identifies cellular subtypes with distinct roles in PDAC progression	20
Cancer-associated fibroblast-derived extracellular vesicles facilitate metastasis in hepatocellular carcinoma by delivering CTGF	20
PAQR5 inhibits the growth and metastasis of clear cell renal cell carcinoma by suppressing the JAK/STAT3 signaling pathway	20
HBO1 determines epithelial-mesenchymal transition and promotes immunotherapy resistance in ovarian cancer cells	19
circRNA_0067717 promotes paclitaxel resistance in nasopharyngeal carcinoma by acting as a scaffold for TRIM41 and p53	19
RACK1 attenuates pancreatic tumorigenesis by suppressing acinar-to-ductal metaplasia through inflammatory signaling modulation	19
Vimentin promotes glioma progression and maintains glioma cell resistance to oxidative phosphorylation inhibition	19
DNA-methylome-derived epigenetic fingerprint as an immunophenotype indicator of durable clinical immunotherapeutic benefits in head and neck squamous cell carcinoma	18
Non-glycanated ΔDCN isoform in muscle invasive bladder cancer mediates cancer stemness and gemcitabine resistance	18
Nilotinib in combination with sunitinib renders MCL-1 for degradation and activates autophagy that overcomes sunitinib resistance in renal cell carcinoma	18
GDF15 induces chemoresistance to oxaliplatin by forming a reciprocal feedback loop with Nrf2 to maintain redox homeostasis in colorectal cancer	18
Tumour-derived exosomal lncRNA SNHG16 induces telocytes to promote metastasis of hepatocellular carcinoma via the miR-942-3p/MMP9 axis	18
Distinct tumor microenvironment landscapes of rectal cancer for prognosis and prediction of immunotherapy response	18
HVEM in acute lymphocytic leukemia facilitates tumour immune escape by inhibiting CD8+ T cell function	18

Cell death in glioblastoma and the central nervous system	17
Plasma cell signatures predict prognosis and treatment efficacy for lung adenocarcinoma	17
Lactate score classification of hepatocellular carcinoma helps identify patients with tumors that respond to immune checkpoint blockade therapy	17
Mapping the immune terrain in lung adenocarcinoma progression: Tfh-like cells in tertiary lymphoid structures	17
Tumor-infiltrating myeloid cells; mechanisms, functional significance, and targeting in cancer therapy	17
Marine derived macrolide bryostatin 4 inhibits the TGF-β signaling pathway against acute erythroleukemia	17
Targeting TRIM24 promotes neuroblastoma differentiation and decreases tumorigenicity via LSD1/CoREST complex	17
Therapeutic exosomes loaded with SERPINA5 attenuated endometrial cancer cell migration via the integrin β1/FAK signaling pathway	17
Characterization and proteomic analysis of plasma-derived small extracellular vesicles in locally advanced rectal cancer patients	17
E3 ubiquitin ligases in cancer stem cells: key regulators of cancer hallmarks and novel therapeutic opportunities	17
Microbial metabolite trimethylamine-N-oxide induces intestinal carcinogenesis through inhibiting farnesoid X receptor signaling	17
Publisher Correction to: RETRACTED ARTICLE: Human bone marrow-derived mesenchymal stem cell-secreted exosomes overexpressing microRNA-34a ameliorate glioblastoma development via down-regulating MYCN	17
Low-dose SAHA enhances CD8+ T cell-mediated antitumor immunity by boosting MHC I expression in non-small cell lung cancer	17
LncRNA MIR4435-2HG drives cancer progression by modulating cell cycle regulators and mTOR signaling in stroma-enriched subtypes of urothelial carcinoma of the bladder	16
Antitumor activity of afatinib in EGFR T790M-negative human oral cancer therapeutically targets mTOR/Mcl-1 signaling axis	16
ADAR1 enhances tumor proliferation and radioresistance in non-small cell lung cancer by interacting with Rad18	16
Integrating bulk and single-cell transcriptomics to elucidate the role and potential mechanisms of autophagy in aging tissue	16
Stiffened tumor microenvironment enhances perineural invasion in breast cancer via integrin signaling	16
Host-derived growth factors drive ERK phosphorylation and MCL1 expression to promote osteosarcoma cell survival during metastatic lung colonization	16
Trained immunity alleviates the progression of melanoma during sepsis-associated immunoparalysis	16
DNASE1L3 inhibits hepatocellular carcinoma by delaying cell cycle progression through CDK2	16
VE-822 upregulates the deubiquitinase OTUD1 to stabilize FHL1 to inhibit the progression of lung adenocarcinoma	15
The m1A-SFRP2-NFAT/TOX axis governs T cell exhaustion in gastric cancer	15
Identifying the effectiveness of 3D culture systems to recapitulate breast tumor tissue in situ	15
RCN2 promotes Nasopharyngeal carcinoma progression by curbing Calcium flow and Mitochondrial apoptosis	15
Targeting human mitochondrial NAD(P)+-dependent malic enzyme (ME2) impairs energy metabolism and redox state and exhibits antileukemic activity in acute myeloid leukemia	15
Allelic expression imbalance of CDKN2A variants in childhood acute lymphoblastic leukemia	15
IFIT1 modulates the proliferation, migration and invasion of pancreatic cancer cells via Wnt/β-catenin signaling	15
Inhibition of PP2A by LB100 sensitizes bladder cancer cells to chemotherapy by inducing p21 degradation	15
Interferon Gamma Inducible Protein 30: from biological functions to potential therapeutic target in cancers	15
Identification of a novel gene signature related to prognosis and metastasis in gastric cancer	15
ABCA6 affects the malignancy of Ewing sarcoma cells via cholesterol-guided inhibition of the IGF1R/AKT/MDM2 axis	15
Triggering immunogenic death of cancer cells by nanoparticles overcomes immunotherapy resistance	15
Integrative proteomics and n-glycoproteomics reveal the synergistic anti-tumor effects of aspirin- and gemcitabine-based chemotherapy on pancreatic cancer cells	14
Crosstalk between oxidative phosphorylation and immune escape in cancer: a new concept of therapeutic targets selection	14
Senolytics: charting a new course or enhancing existing anti-tumor therapies?	14
Roles of NRF2 in DNA damage repair	14
Correction to: ABCA6 affects the malignancy of Ewing sarcoma cells via cholesterol-guided inhibition of the IGF1R/AKT/MDM2 axis	14
Expression of the zinc-finger transcription factor Osterix (SP7) in invasive breast cancer and its prognostic significance	14
CircGLIS3 inhibits thyroid cancer invasion and metastasis through miR-146b-3p/AIF1L axis	14
Crosstalk between long noncoding RNA and microRNA in Cancer	13
Fibroblast subtypes in pancreatic cancer and pancreatitis: from mechanisms to therapeutic strategies	13
Unraveling Th subsets: insights into their role in immune checkpoint inhibitor therapy	13
Correction to: IDH2, a novel target of OGT, facilitates glucose uptake and cellular bioenergy production via NF-κB signaling to promote colorectal cancer progression	13
Low-dose anti-VEGFR2 therapy promotes anti-tumor immunity in lung adenocarcinoma by down-regulating the expression of layilin on tumor-infiltrating CD8+T cells	13
Correction to: CoQ10 reduces glioblastoma growth and infiltration through proteome remodeling and inhibition of angiogenesis and inflammation	13
EGFR blockade confers sensitivity to pan-RAS inhibitors in KRAS-mutated cancers	13
Exploring tumor microenvironment interactions and apoptosis pathways in NSCLC through spatial transcriptomics and machine learning	13
Establishment, characterization, and biobanking of 36 pancreatic cancer organoids: prediction of metastasis in resectable pancreatic cancer	13
miR-4739 promotes epithelial-mesenchymal transition and angiogenesis in “driver gene-negative” non-small cell lung cancer via activating the Wnt/β-catenin signaling	13
TRIM44 regulates tumor immunity in gastric cancer through LOXL2-dependent extracellular matrix remodeling	13
Deciphering fatty acid biosynthesis-driven molecular subtypes in pancreatic ductal adenocarcinoma with prognostic insights	13
Enhanced ZBTB10 expression induced by betulinic acid inhibits gastric cancer progression by inactivating the ARRDC3/ITGB4/PI3K/AKT pathway	13
Efficacy of CDK4/6 Inhibition in colorectal cancer and the role of p16 expression in predicting drug resistance	13
The SLITRK4-CNPY3 axis promotes liver metastasis of gastric cancer by enhancing the endocytosis and recycling of TrkB in tumour cells	12
Heterogeneity, inherent and acquired drug resistance in patient-derived organoid models of primary liver cancer	12
The Ribonuclease ZC3H12A is required for self-inflicted DNA breaks after DNA damage in small cell lung cancer cells	12
Role of nerves in neurofibromatosis type 1-related nervous system tumors	12
Proteasomal deubiquitylase activity enhances cell surface recycling of the epidermal growth factor receptor in non-small cell lung cancer	12
Novel insights into lncRNAs as key regulators of post-translational modifications in cancer: mechanisms and therapeutic potential	12
Inhibition of thioredoxin-1 enhances the toxicity of glycolysis inhibitor 2-deoxyglucose by downregulating SLC1A5 expression in colorectal cancer cells	12
Nucleotide sugar transporter SLC35A2 is involved in promoting hepatocellular carcinoma metastasis by regulating cellular glycosylation	12
Non-canonical role for the ataxia-telangiectasia-Rad3 pathway in STAT3 activation in human multiple myeloma cells	12
STK3 kinase activation inhibits tumor proliferation through FOXO1-TP53INP1/P21 pathway in esophageal squamous cell carcinoma	11
LILRB2 promotes immune escape in breast cancer cells via enhanced HLA-A degradation	11
Loss of RACK1 promotes glutamine addiction via activating AKT/mTOR/ASCT2 axis to facilitate tumor growth in gastric cancer	11
Thymidine kinase 1 indicates resistance to immune checkpoint plus tyrosine kinase inhibition in renal cell carcinoma	11
Correction to: CCL18 secreted from M2 macrophages promotes migration and invasion via the PI3K/Akt pathway in gallbladder cancer	11
Targeting CA9 restricts pancreatic cancer progression through pH regulation and ROS production	11
In-depth quantitative proteomics analysis revealed C1GALT1 depletion in ECC-1 cells mimics an aggressive endometrial cancer phenotype observed in cancer patients with low C1GALT1 expression	11
Discovery of a small molecule ligand of FRS2 that inhibits invasion and tumor growth	11
Correction to: Colorectal cancer organoid models uncover oxaliplatin-resistant mechanisms at single cell resolution	11
Triggering pyroptosis enhances the antitumor efficacy of PARP inhibitors in prostate cancer	11
Dual blockage of P-cadherin and c-Met synergistically inhibits the growth of head and neck cancer	11
A review on the functional characteristics of the c-Myeloproliferative Leukaemia (c-MPL) gene and its isoforms	11
Retraction Note: Downregulation of beta-catenin in chemo-tolerant TNBC through changes in receptor and antagonist profiles of the WNT pathway: Clinical and prognostic implications	11
METTL3 suppresses pancreatic ductal adenocarcinoma progression through activating endogenous dsRNA-induced anti-tumor immunity	11
Activation of the HSP27-AKT axis contributes to gefitinib resistance in non-small cell lung cancer cells independent of EGFR mutations	11
Comprehensive analysis of clinical prognostic features and tumor microenvironment landscape of CD11b+CD64+ patients with acute myeloid leukemia	11
High extracellular matrix stiffness upregulates TNNT1 to awaken dormant tumor cells in liver metastatic niches of gastric cancer	11

Fbxo2 inhibits cell proliferation, migration and invasion by the ubiquitin-mediated degradation of WEE1 in renal cell carcinoma	10
A novel risk score system based on immune subtypes for identifying optimal mRNA vaccination population in hepatocellular carcinoma	10
Presence of regulatory T-cells in endometrial cancer predicts poorer overall survival and promotes progression of tumor cells	10
Therapeutic effects against high-grade glioblastoma mediated by engineered induced neural stem cells combined with GD2-specific CAR-NK	10
Three-dimensional genome architecture in intrahepatic cholangiocarcinoma	10
Effect of infiltrating immune cells in tumor microenvironment on metastasis of hepatocellular carcinoma	10
Retraction Note: Leptin promotes the migration and invasion of breast cancer cells by upregulating ACAT2	10
SPG21, a potential oncogene targeted by miR-128-3p, amplifies HBx-induced carcinogenesis and chemoresistance via activation of TRPM7-mediated JNK pathway in hepatocellular carcinoma	10
CEP55 3’-UTR promotes epithelial–mesenchymal transition and enhances tumorigenicity of bladder cancer cells by acting as a ceRNA regulating miR-497-5p	10
Toxicity profiles of immunochemotherapy for gastric or gastroesophageal junction adenocarcinoma: a systematic review and meta-analysis	10
Fasting in combination with the cocktail Sorafenib:Metformin blunts cellular plasticity and promotes liver cancer cell death via poly-metabolic exhaustion	10
Genomic analysis and filtration of novel prognostic biomarkers based on metabolic and immune subtypes in pancreatic cancer	10
TIMEAS, a promising method for the stratification of testicular germ cell tumor patients with distinct immune microenvironment, clinical outcome and sensitivity to frontline therapies	10
From benign neurofibromas to malignant peripheral nerve sheath tumors (MPNST): a gaming among multiple factors	10
Embracing cancer immunotherapy with manganese particles	10
NK cells as powerful therapeutic tool in cancer immunotherapy	10
Non-canonical function of PHGDH promotes HCC metastasis by interacting with METTL3	10
Effect of neoadjuvant targeted therapy on the tumor microenvironment in resectable lung adenocarcinoma	10
FAP is a prognostic marker, but not a viable therapeutic target for clinical translation in HNSCC	9
The prognostic effect of tumor-associated macrophages in stage I-III colorectal cancer depends on T cell infiltration	9
DNA hypomethylation patterns and their impact on the tumor microenvironment in colorectal cancer	9
ONECUT2 is a druggable driver of luminal to basal breast cancer plasticity	9
Dexmedetomidine promotes colorectal cancer progression via Piwil2 signaling	9
Immunosuppression, immune escape, and immunotherapy in pancreatic cancer: focused on the tumor microenvironment	9
Hepatocyte nuclear factor 4-Alpha: a key regulator in liver carcinogenesis	9
Targeting tumor associated macrophages (TAMs) reprograms tumor immune microenvironment to promote solid tumor immunotherapy	9
AKT-driven epithelial-mesenchymal transition is affected by copper bioavailability in HER2 negative breast cancer cells via a LOXL2-independent mechanism	9
Mitochondria in tumor immune surveillance and tumor therapies targeting mitochondria	9
OrBITS: label-free and time-lapse monitoring of patient derived organoids for advanced drug screening	9
DNA repair in tumor radioresistance: insights from fruit flies genetics	9
Role of BRCA1 in glioblastoma etiology	9
The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancer	9
Fibroblast-derived PI16 enhances tumor immune-suppressive microenvironment via inducing Tregs differentiation	9
Dysregulation of the p53 pathway provides a therapeutic target in aggressive pediatric sarcomas with stem-like traits	9
Correction to: YAP1 acts as a negative regulator of pro-tumor TAZ expression in esophageal squamous cell carcinoma	9
The role of tumor-platelet interplay and micro tumor thrombi during hematogenous tumor metastasis	9
Sirtuin 5-mediated deacetylation of TAZ at K54 promotes melanoma development	8
Cell signaling activation and extracellular matrix remodeling underpin glioma tumor microenvironment heterogeneity and organization	8
BHLHE41, a transcriptional repressor involved in physiological processes and tumor development	8
Molecular actions of exosomes and their theragnostics in colorectal cancer: current findings and limitations	8
CAFs vs. TECs: when blood feuds fuel cancer progression, dissemination and therapeutic resistance	8
Blockade of USP14 potentiates type I interferon signaling and radiation-induced antitumor immunity via preventing IRF3 deubiquitination	8
TENT5A mediates the cancer-inhibiting effects of EGR1 by suppressing the protein stability of RPL35 in hepatocellular carcinoma	8
Establishment of experimental salivary gland cancer models using organoid culture and patient-derived xenografting	8
Perineural invasion in colorectal cancer: mechanisms of action and clinical relevance	8
Exosomes delivering miR-129-5p combined with sorafenib ameliorate hepatocellular carcinoma progression via the KCTD1/HIF-1α/VEGF pathway	8
Correction: Targeting ARHGEF12 promotes neuroblastoma differentiation, MYCN degradation, and reduces tumorigenicity	8
Distinct expression and function of breast cancer metastasis suppressor 1 in mutant P53 glioblastoma	8
Hedgehog ligand and receptor cooperatively regulate EGFR stability and activity in non-small cell lung cancer	8
Clinical value of 18F-FDG PET/CT in patients with newly diagnosed acute leukemia	8
Ferritinophagy induced ferroptosis in the management of cancer	8
The microbiota and renal cell carcinoma	8
A diagnostic model based on transcriptomic analysis reveals inflammation as a potential prognosis factor for hepatoblastoma with hepatocellular carcinoma features	8
A novel pyroptosis-associated lncRNA LINC01133 promotes pancreatic adenocarcinoma development via miR-30b-5p/SIRT1 axis	8