OOIR: Observatory of International Research

Papers

(The TQCC of Cellular Oncology is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Application of circulating tumour cells to predict response to treatment in head and neck cancer	81
Deciphering the molecular landscape: evolutionary progression from gynecomastia to aggressive male breast cancer	71
CoQ10 reduces glioblastoma growth and infiltration through proteome remodeling and inhibition of angiogenesis and inflammation	55
Pathways and outputs orchestrated in tumor microenvironment cells by hypoxia-induced tumor-derived exosomes in pan-cancer	51
Asymmetric post-translational modifications regulate the nuclear translocation of STAT3 homodimers in response to leukemia inhibitory factor	44
Publisher Correction to: RAB37 suppresses the EMT, migration and invasion of gastric cancer cells by mediating autophagic degradation of β-catenin	43
Molecular mechanisms underlying the action of carcinogens in gastric cancer with a glimpse into targeted therapy	39
Dissecting the single-cell transcriptome network of macrophage and identifies a signature to predict prognosis in lung adenocarcinoma	38
The therapeutic potential of exosomes in lung cancer	37
HNRNPH1 stabilizes FLOT2 mRNA in a non-canonical m6A-dependent manner to promote malignant progression in nasopharyngeal carcinoma	37
Methionine-producing tumor micro(be) environment fuels growth of solid tumors	36
Exploring the impact of PDGFD in osteosarcoma metastasis through single-cell sequencing analysis	35
A comprehensive prognostic signature for glioblastoma patients based on transcriptomics and single cell sequencing	34
TRPV4 drives the progression of leiomyosarcoma by promoting ECM1 generation and co-activating the FAK/PI3K/AKT/GSK3β pathway	33
FSCN1 induced PTPRF-dependent tumor microenvironment inflammatory reprogramming promotes lung adenocarcinoma progression via regulating macrophagic glycolysis	33
In vivo study revealed pro-tumorigenic effect of CMTM3 in hepatocellular carcinoma involving the regulation of peroxisome proliferator-activated receptor gamma (PPARγ)	33
Proteomic characterisation of prostate cancer intercellular communication reveals cell type-selective signalling and TMSB4X-dependent fibroblast reprogramming	31
Loss of histone deubiquitinase Bap1 triggers anti-tumor immunity	28
Ubiquilin-4 induces immune escape in gastric cancer by activating the notch signaling pathway	28
OSW-1 induces apoptosis and cyto-protective autophagy, and synergizes with chemotherapy on triple negative breast cancer metastasis	27
High-plex spatial transcriptomic profiling reveals distinct immune components and the HLA class I/DNMT3A/CD8 modulatory axis in mismatch repair-deficient endometrial cancer	27
RAB37 suppresses the EMT, migration and invasion of gastric cancer cells by mediating autophagic degradation of β-catenin	24
RETRACTED ARTICLE: The autocrine glycosylated-GREM1 interacts with TGFB1 to suppress TGFβ/BMP/SMAD-mediated EMT partially by inhibiting MYL9 transactivation in urinary carcinoma	23
Targeting nucleolin improves sensitivity to chemotherapy in acute lymphoblastic leukemia	22
SUMOylation inhibitors activate anti-tumor immunity by reshaping the immune microenvironment in a preclinical model of hepatocellular carcinoma	22

Silencing AHNAK promotes nasopharyngeal carcinoma progression by upregulating the ANXA2 protein	21
TBX21 attenuates colorectal cancer progression via an ARHGAP29/RSK/GSK3β dependent manner	21
The survival prediction analysis and preliminary study of the biological function of YEATS2 in hepatocellular carcinoma	21
TRIM28 promotes tumor growth and metastasis in breast cancer by targeting the BRD7 protein for ubiquitination and degradation	21
Correction to: 3D bioprinted tumor model: a prompt and convenient platform for overcoming immunotherapy resistance by recapitulating the tumor microenvironment	21
Modulation of miR-146b by N6-methyladenosine modification remodels tumor-associated macrophages and enhances anti-PD-1 therapy in colorectal cancer	20
Combined inhibition of AURKA and HSF1 suppresses proliferation and promotes apoptosis in hepatocellular carcinoma by activating endoplasmic reticulum stress	19
RRM2 as a novel prognostic and therapeutic target of NF1-associated MPNST	19
Neuropilin-2 acts a critical determinant for epithelial-to-mesenchymal transition and aggressive behaviors of human head and neck cancer	19
Aberrant expression of circular RNA DHPR facilitates tumor growth and metastasis by regulating the RASGEF1B/RAS/MAPK axis in hepatocellular carcinoma	18
From basic research to clinical application: targeting fibroblast activation protein for cancer diagnosis and treatment	18
Next-generation BCMA-targeted chimeric antigen receptor CARTemis-1: the impact of manufacturing procedure on CAR T-cell features	17
OrganoIDNet: a deep learning tool for identification of therapeutic effects in PDAC organoid-PBMC co-cultures from time-resolved imaging data	17
Spheroid-induced heterogeneity and plasticity of uveal melanoma cells	17
Emerging roles of deubiquitinating enzymes in actin cytoskeleton and tumor metastasis	17
Ezrin accelerates breast cancer liver metastasis through promoting furin-like convertase-mediated cleavage of Notch1	17
Dual anti-angiogenic and anti-metastatic activity of myriocin synergistically enhances the anti-tumor activity of cisplatin	17
Targeting MEK/COX-2 axis improve immunotherapy efficacy in dMMR colorectal cancer with PIK3CA overexpression	16
Prognostic significance of collagen signatures at breast tumor boundary obtained by combining multiphoton imaging and imaging analysis	16
Dipyridamole enhances the anti-cancer ability of aspirin against colorectal cancer by inducing apoptosis in an unfolded protein response-dependent manner	16
Cancer/testis-45A1 promotes cervical cancer cell tumorigenesis and drug resistance by activating oncogenic SRC and downstream signaling pathways	16
Osteopontin secreted from obese adipocytes enhances angiogenesis and promotes progression of pancreatic ductal adenocarcinoma in obesity	16
USP28 promotes tumor progression and glycolysis by stabilizing PKM2/Hif1-α in cholangiocarcinoma	16
Feature-weight based measurement of cancerous transcriptome using cohort-wide and sample-specific information	16
Extracellular vesicles related gene HSPH1 exerts anti-tumor effects in prostate cancer via promoting the stress response of CD8 + T cells	16
Exosomes: a potential diagnostic and treatment modality in the quest for counteracting cancer	16
Iron metabolism in colorectal cancer: a balancing act	15
The composition and roles of gastric stem cells in epithelial homeostasis, regeneration, and tumorigenesis	15
Cystatin F acts as a mediator of immune suppression in glioblastoma	15
The changing microRNA landscape by color and cloudiness: a cautionary tale for nipple aspirate fluid biomarker analysis	15
Small extracellular vesicles promote invadopodia activity in glioblastoma cells in a therapy-dependent manner	15
PAQR5 inhibits the growth and metastasis of clear cell renal cell carcinoma by suppressing the JAK/STAT3 signaling pathway	15
Correction to: Downregulated exosomal microRNA-148b-3p in cancer associated fibroblasts enhance chemosensitivity of bladder cancer cells by downregulating the Wnt/β-catenin pathway and upregulating PT	15
The PPP2R1A cancer hotspot mutant p.R183W increases clofarabine resistance in uterine serous carcinoma cells by a gain-of-function mechanism	15
Integrated analysis of single-cell RNA-seq and bulk RNA-seq reveals immune suppression subtypes and establishes a novel signature for determining the prognosis in lung adenocarcinoma	15
Retraction Note: TRAIL enhances quinacrine-mediated apoptosis in breast cancer cells through induction of autophagy via modulation of p21 and DR5 interactions	14
MT1JP-mediated miR-24-3p/BCL2L2 axis promotes Lenvatinib resistance in hepatocellular carcinoma cells by inhibiting apoptosis	14
Lenalidomide overcomes the resistance to third-generation CD19-CAR-T cell therapy in preclinical models of diffuse large B-cell lymphoma	14
Role of ELMO1 in inflammation and cancer—clinical implications	14
Targeting the Notch-Furin axis with 2-hydroxyoleic acid: a key mechanism in glioblastoma therapy	14
Non-coding RNA regulation of integrins and their potential as therapeutic targets in cancer	14
HDAC6: A unique HDAC family member as a cancer target	14
circRNA_0067717 promotes paclitaxel resistance in nasopharyngeal carcinoma by acting as a scaffold for TRIM41 and p53	13
HVEM in acute lymphocytic leukemia facilitates tumour immune escape by inhibiting CD8+ T cell function	13
Non-glycanated ΔDCN isoform in muscle invasive bladder cancer mediates cancer stemness and gemcitabine resistance	13
GDF15 induces chemoresistance to oxaliplatin by forming a reciprocal feedback loop with Nrf2 to maintain redox homeostasis in colorectal cancer	13
Distinct tumor microenvironment landscapes of rectal cancer for prognosis and prediction of immunotherapy response	13
Nilotinib in combination with sunitinib renders MCL-1 for degradation and activates autophagy that overcomes sunitinib resistance in renal cell carcinoma	13
HBO1 determines epithelial-mesenchymal transition and promotes immunotherapy resistance in ovarian cancer cells	13
DNA-methylome-derived epigenetic fingerprint as an immunophenotype indicator of durable clinical immunotherapeutic benefits in head and neck squamous cell carcinoma	12

Tumour-derived exosomal lncRNA SNHG16 induces telocytes to promote metastasis of hepatocellular carcinoma via the miR-942-3p/MMP9 axis	12
Integrated approach to functional analysis of an ERBB2 variant of unknown significance detected by a cancer gene panel test	12
Mapping the immune terrain in lung adenocarcinoma progression: Tfh-like cells in tertiary lymphoid structures	12
Characterization and proteomic analysis of plasma-derived small extracellular vesicles in locally advanced rectal cancer patients	12
Vimentin promotes glioma progression and maintains glioma cell resistance to oxidative phosphorylation inhibition	12
Microbial metabolite trimethylamine-N-oxide induces intestinal carcinogenesis through inhibiting farnesoid X receptor signaling	11
Targeting TRIM24 promotes neuroblastoma differentiation and decreases tumorigenicity via LSD1/CoREST complex	11
YKL-40 protein expression in human tumor samples and human tumor cell line xenografts: implications for its use in tumor models	11
Cell death in glioblastoma and the central nervous system	11
Plasma cell signatures predict prognosis and treatment efficacy for lung adenocarcinoma	11
Identification of a novel gene signature related to prognosis and metastasis in gastric cancer	11
E3 ubiquitin ligases in cancer stem cells: key regulators of cancer hallmarks and novel therapeutic opportunities	11
Therapeutic exosomes loaded with SERPINA5 attenuated endometrial cancer cell migration via the integrin β1/FAK signaling pathway	11
Low-dose SAHA enhances CD8+ T cell-mediated antitumor immunity by boosting MHC I expression in non-small cell lung cancer	11
Lactate score classification of hepatocellular carcinoma helps identify patients with tumors that respond to immune checkpoint blockade therapy	11
Bile acids increase intestinal marker expression via the FXR/SNAI2/miR-1 axis in the stomach	11
Tumor-infiltrating myeloid cells; mechanisms, functional significance, and targeting in cancer therapy	11
Marine derived macrolide bryostatin 4 inhibits the TGF-β signaling pathway against acute erythroleukemia	11
AKT inhibition sensitizes EVI1 expressing colon cancer cells to irinotecan therapy by regulating the Akt/mTOR axis	10
Host-derived growth factors drive ERK phosphorylation and MCL1 expression to promote osteosarcoma cell survival during metastatic lung colonization	10
Antitumor activity of afatinib in EGFR T790M-negative human oral cancer therapeutically targets mTOR/Mcl-1 signaling axis	10
LncRNA MIR4435-2HG drives cancer progression by modulating cell cycle regulators and mTOR signaling in stroma-enriched subtypes of urothelial carcinoma of the bladder	10
Identifying the effectiveness of 3D culture systems to recapitulate breast tumor tissue in situ	10
VE-822 upregulates the deubiquitinase OTUD1 to stabilize FHL1 to inhibit the progression of lung adenocarcinoma	10
Publisher Correction to: RETRACTED ARTICLE: Human bone marrow-derived mesenchymal stem cell-secreted exosomes overexpressing microRNA-34a ameliorate glioblastoma development via down-regulating MYCN	10
Integrating bulk and single-cell transcriptomics to elucidate the role and potential mechanisms of autophagy in aging tissue	10
ADAR1 enhances tumor proliferation and radioresistance in non-small cell lung cancer by interacting with Rad18	10
Hippocalcin-like 1 is a key regulator of LDHA activation that promotes the growth of non-small cell lung carcinoma	10
Targeting human mitochondrial NAD(P)+-dependent malic enzyme (ME2) impairs energy metabolism and redox state and exhibits antileukemic activity in acute myeloid leukemia	10
Stiffened tumor microenvironment enhances perineural invasion in breast cancer via integrin signaling	10
Trained immunity alleviates the progression of melanoma during sepsis-associated immunoparalysis	10
DNASE1L3 inhibits hepatocellular carcinoma by delaying cell cycle progression through CDK2	10
ABCA6 affects the malignancy of Ewing sarcoma cells via cholesterol-guided inhibition of the IGF1R/AKT/MDM2 axis	9
IFIT1 modulates the proliferation, migration and invasion of pancreatic cancer cells via Wnt/β-catenin signaling	9
Spatiotemporal modulation of SMAD4 by HBx is required for cellular proliferation in hepatitis B-related liver cancer	9
RCN2 promotes Nasopharyngeal carcinoma progression by curbing Calcium flow and Mitochondrial apoptosis	9
Expression of the zinc-finger transcription factor Osterix (SP7) in invasive breast cancer and its prognostic significance	9
Crosstalk between oxidative phosphorylation and immune escape in cancer: a new concept of therapeutic targets selection	9
Triggering immunogenic death of cancer cells by nanoparticles overcomes immunotherapy resistance	9
Integrative proteomics and n-glycoproteomics reveal the synergistic anti-tumor effects of aspirin- and gemcitabine-based chemotherapy on pancreatic cancer cells	9
Interferon Gamma Inducible Protein 30: from biological functions to potential therapeutic target in cancers	9
Roles of NRF2 in DNA damage repair	9
Allelic expression imbalance of CDKN2A variants in childhood acute lymphoblastic leukemia	9
Inhibition of PP2A by LB100 sensitizes bladder cancer cells to chemotherapy by inducing p21 degradation	9
Senolytics: charting a new course or enhancing existing anti-tumor therapies?	9