FEBS Open Bio

Papers
(The TQCC of FEBS Open Bio is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
Issue Information88
Issue Information72
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2‐dodecyl‐6‐methoxycyclohexa‐2,5‐diene‐1,4‐dione mediates the effect of ROS‐enhanced PI3K/Akt/mTOR pathway on autophagy in breast cancer56
Antitubercular potential and pH‐driven mode of action of salicylic acid derivatives50
RETRACTION: LKB1 Suppresses Androgen Synthesis in a Mouse Model of Hyperandrogenism via IGF‐1 Signaling48
Interaction of RECQL4 with poly(ADP‐ribose) is critical for the DNA double‐strand break response in human cells47
Posters Annex42
Regorafenib as a potential drug for severe COVID‐19: inhibition of inflammasome activation in mice40
Anti‐inflammatory properties of ophioglonin derived from the fern Ophioglossum vulgatum L. via inactivating NFκB and MAPK signaling pathways40
Prognostic significance of the rhoGTPase RHOVand its role in tumor immune cell infiltration: a comprehensive pan‐cancer analysis35
Nitric oxide inhibits endothelial cell apoptosis by inhibiting cysteine‐dependent SOD1 monomerization34
Lewis fucose is a key moiety for the recognition of histo‐blood group antigens by GI.9 norovirus, as revealed by structural analysis33
Suppression of intrahepatic cholangiocarcinoma cell growth by SKI via upregulation of the CDK inhibitor p2132
Targeted recombination of homologous chromosomes using CRISPR‐Cas931
Dexamethasone induces p21cip1/waf1 expression via FoxO3a independently of the Lamin A/C‐HDAC2 interaction in Ataxia Telangiectasia31
Analgesic effects of nerve growth factor‐directed monoclonal antibody on diabetic neuralgia in an animal model30
Structural analysis of an Asterias rubens peptide indicates the presence of a disulfide‐directed β‐hairpin fold29
Glucose 6‐phosphate dehydrogenase variants increase NADPH pools for yeast isoprenoid production29
A mouse model of lung cancer induced via intranasal injection for anticancer drug screening and evaluation of pathology28
Membrane‐acting biomimetic peptoids against visceral leishmaniasis27
KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO<27
Teaching, research or balanced? An exploration of the experiences of biomedical scientists working in UK medical schools26
Comparative transcriptomics of the Djungarian hamster hypothalamus during short photoperiod acclimation and spontaneous torpor26
CCR4‐IL2 bispecific immunotoxin is more effective than brentuximab for targeted therapy of cutaneous T‐cell lymphoma in a mouse CTCL model25
Accumulation of amyloid beta (Aβ) and amyloid precursor protein (APP) in tumors formed by a mouse xenograft model of inflammatory breast cancer24
Issue Information23
Characterization of the thermophilic xylanase Fsa02490Xyn from the hyperthermophile Fervidibacter sacchari belonging to glycoside hydrolase family 1023
Withdrawal: Urinary exosomal tRNA‐derived small RNA signatures as a predictive biomarker in lung cancer22
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Talks22
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Development and single‐particle analysis of hybrid extracellular vesicles fused with liposomes using viral fusogenic proteins21
Science students' perspectives on how to decrease the stigma of failure21
Characterization and comparison of recombinant full‐length ursine and human sex hormone‐binding globulin21
SV40 T antigen helicase domain regions responsible for oligomerisation regulate Okazaki fragment synthesis initiation20
GRK5‐mediated inflammation and fibrosis exert cardioprotective effects during the acute phase of myocardial infarction19
Nanoparticles of folic acid‐methyl‐β‐cyclodextrin (FA‐MβCD)/adamantane‐albumin exhibit enhanced antitumor activity compared with FA‐MβCD alone19
Phenotypical and biochemical characterization of murine psoriasiform and fibrotic skin disease models in Stabilin‐deficient mice18
High growth hormone serum partially protects mice against Trypanosoma cruzi infection18
YAPTEAD inhibition is associated with upregulation of an androgen receptor mediated transcription program providing therapeutic escape17
Cantharidin downregulates PSD1 expression and inhibits autophagic flux in yeast cells17
DDR2 signaling and mechanosensing orchestrate neuroblastoma cell fate through different transcriptome mechanisms16
Enhancing transporter activity in heterologous expression systems with SAHA: a 2500‐times more potent and odorless alternative to butyrate16
Fibroblast growth factor 2 acts as an upstream regulator of inhibition of pulmonary fibroblast activation16
MTHFD2 promotes ovarian cancer growth and metastasis via activation of the STAT3 signaling pathway16
Synergistic antibacterial activity of baicalin in combination with oxacillin sodium against methicillin‐resistant Staphylococcus aureus15
Metabolic reprogramming heterogeneity in chronic kidney disease15
Retraction statement: Ubiquitin ligase SMURF1 functions as a prognostic marker and promotes growth and metastasis of clear cell renal cell carcinoma15
The spike glycoprotein of highly pathogenic human coronaviruses: structural insights for understanding infection, evolution and inhibition15
Viral and cellular translation during SARS‐CoV‐2 infection15
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise14
The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity14
Triosephosphate isomerase of Streptococcus pneumoniae is released extracellularly by autolysis and binds to host plasminogen to promote its activation14
A potential tumor suppressor role of PLK2 in glioblastoma14
NMR screening of low molecular weight inhibitors targeting the papain‐like protease (PLPro) of SARSCoV‐213
The mTOR–lysosome axis at the centre of ageing13
Lactate administration does not affect denervation‐induced loss of mitochondrial content and muscle mass in mice13
Issue Information13
Characterization of the promoter region of the murine Catsper2 gene13
Serving the scientific community: FEBS Open Bio in 202413
Reviewers acknowledgement12
IFNγ induces Bcl3 expression by JAK1/STAT1/p65 signaling, resulting in increased IL‐8 expression in ovarian cancer cells12
Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions12
A framework for decolonising and diversifying biomedical sciences curricula: rediscovery, representation and readiness12
Ezetimibe inhibits the migration and invasion of triple‐negative breast cancer cells by targeting TGFβ2 and EMT12
RETRACTION: Bach2 overexpression represses Th9 cell differentiation by suppressing IRF4 expression in systemic lupus erythematosus12
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Multiple time‐dependent pathophysiological changes in a rabbit model of high‐fat diet‐induced hyperlipidemia12
Bovine natural antibody IgM inhibits the binding of human norovirus protruding domain to its HBGA receptors12
Metabolic changes induced by DNA damage in Ramos cells: exploring the role of mTORC1 complex12
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The composition of the lung microbiome differs between patients with dermatomyositis and rheumatoid arthritis associated with interstitial lung disease11
Extracellular RNA transfer from non‐malignant human cholangiocytes can promote cholangiocarcinoma growth11
Ceruloplasmin overexpression is associated with oncogenic pathways and poorer survival rates in clear‐cell renal cell carcinoma11
Overexpression of BcERF3 increases the biosynthesis of saikosaponins in Bupleurum chinense11
Glycolipids in Parkinson's disease: beyond neuronal function11
Evaluation of binding activities of a putative lipoprotein LIC_13355 of Leptospira spp.11
Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction11
Multi‐omics‐based analysis of high grade serous ovarian cancer subtypes reveals distinct molecular processes linked to patient prognosis11
Selective proteasome degradation of C‐terminally‐truncated human WFS1 in pancreatic beta cells10
HELQ deficiency impairs the induction of primordial germ cell‐like cells10
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Chloroplast genomes of two Pueraria DC. species: sequencing, comparative analysis and molecular marker development10
Prediction of chaperonin GroE substrates using small structural patterns of proteins10
Structural investigations on the mitochondrial uncouplers niclosamide and FCCP10
Polysaccharide utilization loci encoded DUF1735 likely functions as membrane‐bound spacer for carbohydrate active enzymes10
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Identification and functional comparison of novel alternatively spliced isoforms of human YAP10
Alfaxalone does not have long‐term effects on goldfish pyramidal neuron action potential properties or GABAA receptor currents10
Issue Information10
An open chat with… Johannes Herrmann10
DDX3 participates in miRNA biogenesis and RNA interference through translational control of PACT and interaction with AGO210
A systems biological analysis of the ATF4‐GADD34‐CHOP regulatory triangle upon endoplasmic reticulum stress9
Long noncoding RNAMEG3 inhibits oral squamous cell carcinoma progression via GATA39
The crystal structure of methanogen McrD, a methyl‐coenzyme M reductase‐associated protein9
Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach9
Reduced FRG1 expression promotes angiogenesis via activation of the FGF2‐mediated ERK/AKT pathway9
An efficient strategy for producing RNA‐free Nucleocapsid protein of SARSCoV‐2 for biochemical and structural investigations9
Earthing effects on mitochondrial function: ATP production and ROS generation9
FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production9
Myeloperoxidase inhibition protects bone marrow mononuclear cells from DNA damage induced by the TOP2 poison anti‐cancer drug etoposide9
FSH enhances the inflammatory response of macrophages in the knee joint possibly through the NFκB pathway9
Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss9
‘Let's work together to pass medical school’: a qualitative study of medical student attitudes to teamwork, competition and collaboration9
Microglia heterogeneity in health and disease8
Issue Information8
Time‐dependent effects of hypoxia on cell metabolism, signaling, and iron homeostasis in the hematopoietic progenitor model KG1a8
Identification of testicular cancer immune infiltrates and novel immune cell subtypes8
Reviewers acknowledgement8
A comparative study of mouse bone marrow mesenchymal stem cells isolated using three easy‐to‐perform approaches8
Erratum to: BAP1 promotes viability and migration of ECA109 cells through KLF5/CyclinD1/FGF‐BP18
Ensuring image integrity in the digital age8
The anti‐cancer effect of epigallocatechin‐3‐O‐gallate against multiple myeloma cells is potentiated by 5,7‐dimethoxyflavone8
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Cell‐specific genome‐scale metabolic modeling of SARS‐CoV‐2‐infected lung to identify antiviral enzymes8
NPC1 promotes the progression of hepatocellular carcinoma by mediating the accumulation of neutrophils into the tumor microenvironment8
Issue Information8
Phosphorylation of RyR2 Ser‐2814 by CaMKII mediates β1‐adrenergic stress induced Ca2+‐leak from the sarcoplasmic reticulum8
Issue Information8
Cancer cells forgo translating mRNA transcribed from genes of nonspecialized tasks8
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Entering the second decade: FEBS Open Bio in 20228
Lkb1 loss in regulatory T cells leads to dysregulation of hematopoietic stem cell expansion and differentiation in bone marrow8
Strengthening the bond with the scientific community: FEBS Open Bio in 20258
Corrigendum to “Endoplasmic reticulum stress associated with lead (Pb)‐induced olfactory epithelium toxicity in an olfactory dark basal cell line” https://doi.org/10.1002/2211‐5463.137148
Gene expression and characterization of clonally derived murine embryonic brown and brite adipocytes8
The first crystal structure of a family 45 glycoside hydrolase from a brown‐rot fungus, Gloeophyllum trabeumGtCel45A8
Expression and purification of E140 protein antigen fragments of Plasmodium vivax and Plasmodium berghei for serological assays7
Metallodrugs: an approach against invasion and metastasis in cancer treatment7
Report on the FEBS‐IUBMB‐ENABLE 1st International Molecular Biosciences PhD and Postdoc Conference7
Oxidative stress in the tumor microenvironment in gastric cancer and its potential role in immunotherapy7
Ferritin heavy chain (FTH1) exerts significant antigrowth effects in breast cancer cells by inhibiting the expression of c‐MYC7
Functional parameters of spermatozoa obtained by a new selection device7
Mitochondrial complex IV defects induce metabolic and signaling perturbations that expose potential vulnerabilities in HCT116 cells7
Histone chaperone‐mediated co‐expression assembly of tetrasomes and nucleosomes7
Cotton flower metabolites inhibit SARS‐CoV‐2 main protease7
Revealing protein structures: crystallization of protein‐ligand complexes – co‐crystallization and crystal soaking7
Intermittent induction of LEA peptide by lactose enhances the expression of insecticidal proteins in Bacillus thuringiensis7
The splicing factor DHX38/PRP16 is required for ovarian clear cell carcinoma tumorigenesis, as revealed by a CRISPR‐Cas9 screen7
On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF4697
FEBS Open Bio: past, present and future7
Retraction: Kinesin family member 3A stimulates cell proliferation, migration, and invasion of bladder cancer cells in vitro and in vivo7
Benefits of exercise on cognitive impairment in alcohol use disorder following alcohol withdrawal7
The cryo‐EM structure of full‐length RAD52 protein contains an undecameric ring7
Development of a fully human anti‐GITR antibody with potent antitumor activity using H2L2 mice7
The cytotoxic action of BCI is not dependent on its stated DUSP1 or DUSP6 targets in neuroblastoma cells7
Issue Information6
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Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—20246
The interplay between pathogens and Atg8 family proteins: thousand‐faced interactions6
Learning objectives: an epiphany6
Liraglutide enhances the effect of checkpoint blockade in lung and liver cancers through the inhibition of neutrophil extracellular traps6
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Characterisation of a common hotspot variant in acute intermittent porphyria sheds light on the mechanism of hydroxymethylbilane synthase function6
Intracellular protein crystallization in living insect cells6
RAB31 in glioma‐derived endothelial cells promotes glioma cell invasion via extracellular vesicle‐mediated enrichment of MYO1C6
Issue Information6
Mutations in RPS19 may affect ribosome function and biogenesis in Diamond Blackfan anemia6
A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers6
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Real‐world genomic landscape of colon and rectal cancer6
Retraction statement: MicroRNA‐431 inhibits migration and invasion of hepatocellular carcinoma cells by targeting the ZEB1‐mediated epithelial–mesenchymal transition6
High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer6
Issue Information6
Toll‐like receptor 9 signaling in chronic lymphocytic leukemia cell lines6
Development of a mouse embryonic stem cell model for investigating the functions of the linker histone H1‐46
Front Cover6
A brief overview of BNIP3L/NIX receptor‐mediated mitophagy6
Correction to “Characterization of the cHS4 insulator in mouse embryonic stem cells”6
Overexpressed Smurf1 is degraded in glioblastoma cells through autophagy in a p62‐dependent manner6
Retraction statement: miR‐944 inhibits metastasis of gastric cancer by preventing the epithelial–mesenchymal transition via MACC1/Met/AKT signaling6
Talks6
CDK5 interacts with MST2 and modulates the Hippo signalling pathway6
Analysis of the regulation of undecaprenyl diphosphate dephosphorylation in Escherichia coli6
Tyr76 is essential for the cold adaptation of a class II glutaredoxin 4 with a heat‐labile structure from the Arctic bacteriumSphingomonassp.6
Characterization of the complete chloroplast genome of Rhodiola sachalinensis and comparative analysis with its congeneric plants6
Issue Information6
Establishment of a risk score model for bladder urothelial carcinoma based on energy metabolism‐related genes and their relationships with immune infiltration6
Isolation and characterization of peritoneal microvascular pericytes5
MYPT1 inhibits the metastasis of renal clear cell carcinoma via the MAPK8/N‐cadherin pathway5
On the design of a constitutively active peptide asparaginyl ligase for facile protein conjugation5
WDHD1 is over‐expressed in nasopharyngeal carcinoma and may control the expression of ITGAV5
Biochemical characterization of the human ubiquitous glucose‐6‐phosphatase in neutrophil granulocytes5
The dynamics of cell death patterns and regeneration during acute liver injury in mice5
Identification and analysis of short indels inducing exon extension/shrinkage events5
Knockdown of TMEM160 leads to an increase in reactive oxygen species generation and the induction of the mitochondrial unfolded protein response5
Development and validation of a four‐lipid metabolism gene signature for diagnosis of pancreatic cancer5
Acquired and intrinsic resistance to vemurafenib in BRAFV600E‐driven melanoma brain metastases5
Intrabacterial lipid inclusion‐associated proteins: a core machinery conserved from saprophyte Actinobacteria to the human pathogen Mycobacterium tuberculosis5
SMARCA4 mutations and expression in lung adenocarcinoma: prognostic significance and impact on the immunotherapy response5
Tryptophan‐sensing receptor GPR142 expression levels are directly regulated by proinflammatory cytokines in ghrelin‐producing cells5
Biochemical and in silico identification of the active site and the catalytic mechanism of the circadian deadenylase HESPERIN5
Malus pumila Mill. cv Annurca apple extract might be therapeutically useful against oxidative stress and patterned hair loss5
On the difficulties of characterizing weak protein interactions that are critical for neurotransmitter release5
Expression of a Crry/p65 is reduced in acute lung injury induced by extracellular histones5
Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria5
Nanoscale‐tipped wire array injections transfer DNA directly into brain cells ex vivo and in vivo5
Biological and clinical implications of metastasis‐associated circular RNAs in oesophageal squamous cell carcinoma5
RETRACTION: MicroRNA‐498 Reduces the Proliferation and Invasion of Colorectal Cancer Cells via Targeting Bcl‐25
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Issue Information5
hnRNP A1 and hnRNP C associate with miR‐17 and miR‐18 in thyroid cancer cells5
Feeder cells treated with ethanol can be used to maintain self‐renewal and pluripotency of human pluripotent stem cells5
Flow cytometric resolution of yeast is affected by enzymatic treatment and culture media5
Beta cell regeneration upon magainin and growth hormone treatment as a possible alternative to insulin therapy5
Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study5
Biochemical characterization and gene structure analysis of the 24‐kDa glutathione transferase sigma from Taenia solium5
Diacylglycerol kinase ζ interacts with sphingomyelin synthase 1 and sphingomyelin synthase‐related protein via different regions5
Menthol‐like cooling compounds, including (R)‐(‐)‐carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K5
Using a ‘Students as Partners’ model to develop an authentic assessment promoting employability skills in undergraduate life science education5
Diagnostic and therapeutic targeting of pathological tau proteins in neurodegenerative disorders5
Structure prediction analysis of human core TIM23 complex reveals conservation of the protein translocation mechanism5
Hippocampal tau‐induced GRIN3A deficiency in Alzheimer's disease4
Alcohol induces α2‐6sialo mucin O‐glycans that kill U937 macrophages mediated by sialic acid‐binding immunoglobulin‐like lectin 7 (Siglec 7)4
Abstracts4
Determination of the optimal connector length to enhance stability of backbone‐circularized granulocyte colony‐stimulating factor4
Corrigendum to: Identification and expression analysis of LEA gene family members in pepper (Capsicum annuum L.) https://doi.org/10.1002/2211‐5463.137184
The role of RNA regulators, quorum sensing and c‐di‐GMP in bacterial biofilm formation4
Exploring gene regulatory interaction networks and predicting therapeutic molecules for hypopharyngeal cancer and EGFR‐mutated lung adenocarcinoma4
Functional analysis of the N‐terminal region of acetylxylan esterase from Caldanaerobacter subterraneus subsp. tengcongensis4
The protein tyrosine phosphatase PPH‐7 is required for fertility and embryonic development in C. elegans at elevated temperatures4
ARL2 is required for homologous recombination repair and colon cancer stem cell survival4
Identifying prognostic targets in metastatic prostate cancer beyond AR4
Withdrawal statement: [Liu, X., Qiao, L., Zhang, H., Zhang, C., Ding, R., Kang, J., Liu, Y., Lin, J. and Yan, X. (2023), Argonaute 2 regulates LPS‐induced inflammation in microglial BV2 cells by targe4
Comparative transcriptomics of the garden dormouse hypothalamus during hibernation4
Cardiovascular risk of dietary trimethylamine oxide precursors and the therapeutic potential of resveratrol and its derivatives4
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Issue Information4
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LRRK2 negatively regulates glucose tolerance via regulation of membrane translocation of GLUT4 in adipocytes4
Kinetic characterization of amino acid activation by aminoacyl‐tRNA synthetases using radiolabelled γ‐[32P]ATP4
Fluoxetine partially alleviates inflammation in the kidney of socially stressed male C57 BL/6 mice4
Titanium particles inhibit bone marrow mesenchymal stem cell osteogenic differentiation through the MAPK signaling pathway4
Identification of ferroptosis‐related genes as potential biomarkers of tongue squamous cell carcinoma using an integrated bioinformatics approach4
Corrigendum to: Determination of the optimal concentration and duration of C5aR antagonist application in an inflammatory model of human dental pulp cells4
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Obesity‐induced oxidative stress and mitochondrial dysfunction negatively affect sperm quality4
Issue Information4
Nuclear endonuclease G controls cell proliferation in ovarian cancer4
Issue Information4
Retraction statement: microRNA‐497 inhibits cell proliferation and induces apoptosis by targeting YAP1 in human hepatocellular carcinoma4
Hesperidin enhances intestinal barrier function in Caco‐2 cell monolayers via AMPK‐mediated tight junction‐related proteins4
A novel plasmid‐based experimental system in Saccharomyces cerevisiae that enables the introduction of 10 different plasmids into cells4
How hydrolytic exoribonucleases impact human disease: Two sides of the same story4
Microbiological investigation of pregnancies following vaginal radical trachelectomy using 16S rRNA sequencing of FFPE placental specimens4
Lipid dysmetabolism in ceruloplasmin‐deficient mice revealed both in vivo and ex vivo by MRI, MRS and NMR analyses4
Structures of distantly related interacting protein homologs are less divergent than non‐interacting homologs4
Oleanolic acid alleviates obesity‐induced skeletal muscle atrophy via the PI3K/Akt signaling pathway4
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