FEBS Open Bio

Article	Citations
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Issue Information	60
Issue Information	60
2‐dodecyl‐6‐methoxycyclohexa‐2,5‐diene‐1,4‐dione mediates the effect of ROS‐enhanced PI3K/Akt/mTOR pathway on autophagy in breast cancer	51
Comparative transcriptomics of the Djungarian hamster hypothalamus during short photoperiod acclimation and spontaneous torpor	49
RETRACTION: LKB1 Suppresses Androgen Synthesis in a Mouse Model of Hyperandrogenism via IGF‐1 Signaling	49
Posters Annex	45
Interaction of RECQL4 with poly(ADP‐ribose) is critical for the DNA double‐strand break response in human cells	44
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics	41
Issue Information	36
Anti‐inflammatory properties of ophioglonin derived from the fern Ophioglossum vulgatum L. via inactivating NF‐κB and MAPK signaling pathways	36
A mouse model of lung cancer induced via intranasal injection for anticancer drug screening and evaluation of pathology	34
Prognostic significance of the rhoGTPase RHOVand its role in tumor immune cell infiltration: a comprehensive pan‐cancer analysis	34
CCR4‐IL2 bispecific immunotoxin is more effective than brentuximab for targeted therapy of cutaneous T‐cell lymphoma in a mouse CTCL model	34
KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO<	31
Nitric oxide inhibits endothelial cell apoptosis by inhibiting cysteine‐dependent SOD1 monomerization	31
Accumulation of amyloid beta (Aβ) and amyloid precursor protein (APP) in tumors formed by a mouse xenograft model of inflammatory breast cancer	29
Lewis fucose is a key moiety for the recognition of histo‐blood group antigens by GI.9 norovirus, as revealed by structural analysis	29
Glucose 6‐phosphate dehydrogenase variants increase NADPH pools for yeast isoprenoid production	28
Characterization of the thermophilic xylanase Fsa02490Xyn from the hyperthermophile Fervidibacter sacchari belonging to glycoside hydrolase family 10	26
Membrane‐acting biomimetic peptoids against visceral leishmaniasis	26
Suppression of intrahepatic cholangiocarcinoma cell growth by SKI via upregulation of the CDK inhibitor p21	26
Dexamethasone induces p21cip1/waf1 expression via FoxO3a independently of the Lamin A/C‐HDAC2 interaction in Ataxia Telangiectasia	25
Targeted recombination of homologous chromosomes using CRISPR‐Cas9	23
Regorafenib as a potential drug for severe COVID‐19: inhibition of inflammasome activation in mice	23

Structural analysis of an Asterias rubens peptide indicates the presence of a disulfide‐directed β‐hairpin fold	23
Analgesic effects of nerve growth factor‐directed monoclonal antibody on diabetic neuralgia in an animal model	23
Teaching, research or balanced? An exploration of the experiences of biomedical scientists working in UK medical schools	23
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Viral and cellular translation during SARS‐CoV‐2 infection	22
Antitubercular potential and pH‐driven mode of action of salicylic acid derivatives	22
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Characterization of the promoter region of the murine Catsper2 gene	20
Fibroblast growth factor 2 acts as an upstream regulator of inhibition of pulmonary fibroblast activation	19
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise	19
A potential tumor suppressor role of PLK2 in glioblastoma	19
The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity	18
Cantharidin downregulates PSD1 expression and inhibits autophagic flux in yeast cells	17
Science students' perspectives on how to decrease the stigma of failure	17
Characterization and comparison of recombinant full‐length ursine and human sex hormone‐binding globulin	17
SV40 T antigen helicase domain regions responsible for oligomerisation regulate Okazaki fragment synthesis initiation	16
GRK5‐mediated inflammation and fibrosis exert cardioprotective effects during the acute phase of myocardial infarction	16
Nanoparticles of folic acid‐methyl‐β‐cyclodextrin (FA‐MβCD)/adamantane‐albumin exhibit enhanced antitumor activity compared with FA‐MβCD alone	16
High growth hormone serum partially protects mice against Trypanosoma cruzi infection	15
Enhancing transporter activity in heterologous expression systems with SAHA: a 2500‐times more potent and odorless alternative to butyrate	15
YAP‐TEAD inhibition is associated with upregulation of an androgen receptor mediated transcription program providing therapeutic escape	15
Retraction statement: Ubiquitin ligase SMURF1 functions as a prognostic marker and promotes growth and metastasis of clear cell renal cell carcinoma	14
Talks	14
The spike glycoprotein of highly pathogenic human coronaviruses: structural insights for understanding infection, evolution and inhibition	14
Withdrawal: Urinary exosomal tRNA‐derived small RNA signatures as a predictive biomarker in lung cancer	14
Phenotypical and biochemical characterization of murine psoriasiform and fibrotic skin disease models in Stabilin‐deficient mice	13
Development and single‐particle analysis of hybrid extracellular vesicles fused with liposomes using viral fusogenic proteins	13
NMR screening of low molecular weight inhibitors targeting the papain‐like protease (PLPro) of SARS‐CoV‐2	13
Synergistic antibacterial activity of baicalin in combination with oxacillin sodium against methicillin‐resistant Staphylococcus aureus	13
DDR2 signaling and mechanosensing orchestrate neuroblastoma cell fate through different transcriptome mechanisms	13
A framework for decolonising and diversifying biomedical sciences curricula: rediscovery, representation and readiness	13
Triosephosphate isomerase of Streptococcus pneumoniae is released extracellularly by autolysis and binds to host plasminogen to promote its activation	13
The mTOR–lysosome axis at the centre of ageing	13
Metabolic reprogramming heterogeneity in chronic kidney disease	13
Issue Information	12
Metabolic changes induced by DNA damage in Ramos cells: exploring the role of mTORC1 complex	12
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Serving the scientific community: FEBS Open Bio in 2024	12
The composition of the lung microbiome differs between patients with dermatomyositis and rheumatoid arthritis associated with interstitial lung disease	12
RETRACTION: Bach2 overexpression represses Th9 cell differentiation by suppressing IRF4 expression in systemic lupus erythematosus	12
Reviewers acknowledgement	12
Ezetimibe inhibits the migration and invasion of triple‐negative breast cancer cells by targeting TGFβ2 and EMT	12
Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions	12
Bovine natural antibody IgM inhibits the binding of human norovirus protruding domain to its HBGA receptors	12
Evaluation of binding activities of a putative lipoprotein LIC_13355 of Leptospira spp.	11
Multi‐omics‐based analysis of high grade serous ovarian cancer subtypes reveals distinct molecular processes linked to patient prognosis	11
Overexpression of BcERF3 increases the biosynthesis of saikosaponins in Bupleurum chinense	11
Glycolipids in Parkinson's disease: beyond neuronal function	11
Multiple time‐dependent pathophysiological changes in a rabbit model of high‐fat diet‐induced hyperlipidemia	10

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction	10
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Earthing effects on mitochondrial function: ATP production and ROS generation	10
Chloroplast genomes of two Pueraria DC. species: sequencing, comparative analysis and molecular marker development	10
Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival	10
Structural investigations on the mitochondrial uncouplers niclosamide and FCCP	10
A systems biological analysis of the ATF4‐GADD34‐CHOP regulatory triangle upon endoplasmic reticulum stress	10
An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations	10
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IFNγ induces Bcl3 expression by JAK1/STAT1/p65 signaling, resulting in increased IL‐8 expression in ovarian cancer cells	10
Issue Information	10
Reduced FRG1 expression promotes angiogenesis via activation of the FGF2‐mediated ERK/AKT pathway	10
Myeloperoxidase inhibition protects bone marrow mononuclear cells from DNA damage induced by the TOP2 poison anti‐cancer drug etoposide	10
Selective proteasome degradation of C‐terminally‐truncated human WFS1 in pancreatic beta cells	9
Alfaxalone does not have long‐term effects on goldfish pyramidal neuron action potential properties or GABAA receptor currents	9
An open chat with… Johannes Herrmann	9
Long noncoding RNAMEG3 inhibits oral squamous cell carcinoma progression via GATA3	9
The crystal structure of methanogen McrD, a methyl‐coenzyme M reductase‐associated protein	9
Prediction of chaperonin GroE substrates using small structural patterns of proteins	9
HELQ deficiency impairs the induction of primordial germ cell‐like cells	9
FSH enhances the inflammatory response of macrophages in the knee joint possibly through the NFκB pathway	9
Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach	9
Identification and functional comparison of novel alternatively spliced isoforms of human YAP	9
Polysaccharide utilization loci encoded DUF1735 likely functions as membrane‐bound spacer for carbohydrate active enzymes	9
FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production	9
Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss	9
DDX3 participates in miRNA biogenesis and RNA interference through translational control of PACT and interaction with AGO2	8
Time‐dependent effects of hypoxia on cell metabolism, signaling, and iron homeostasis in the hematopoietic progenitor model KG1a	8
The first crystal structure of a family 45 glycoside hydrolase from a brown‐rot fungus, Gloeophyllum trabeumGtCel45A	8
Issue Information	8
Cell‐specific genome‐scale metabolic modeling of SARS‐CoV‐2‐infected lung to identify antiviral enzymes	8
Issue Information	8
Ensuring image integrity in the digital age	8
Identification of testicular cancer immune infiltrates and novel immune cell subtypes	8
Lkb1 loss in regulatory T cells leads to dysregulation of hematopoietic stem cell expansion and differentiation in bone marrow	8
Gene expression and characterization of clonally derived murine embryonic brown and brite adipocytes	8
Reviewers acknowledgement	8
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‘Let's work together to pass medical school’: a qualitative study of medical student attitudes to teamwork, competition and collaboration	8
A comparative study of mouse bone marrow mesenchymal stem cells isolated using three easy‐to‐perform approaches	8
Microglia heterogeneity in health and disease	8
Cancer cells forgo translating mRNA transcribed from genes of nonspecialized tasks	8
The anti‐cancer effect of epigallocatechin‐3‐O‐gallate against multiple myeloma cells is potentiated by 5,7‐dimethoxyflavone	8
Erratum to: BAP1 promotes viability and migration of ECA109 cells through KLF5/CyclinD1/FGF‐BP1	8
NPC1 promotes the progression of hepatocellular carcinoma by mediating the accumulation of neutrophils into the tumor microenvironment	8
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Entering the second decade: FEBS Open Bio in 2022	8
Expression and purification of E140 protein antigen fragments of Plasmodium vivax and Plasmodium berghei for serological assays	7
The cytotoxic action of BCI is not dependent on its stated DUSP1 or DUSP6 targets in neuroblastoma cells	7
Strengthening the bond with the scientific community: FEBS Open Bio in 2025	7
Issue Information	7
Development of a fully human anti‐GITR antibody with potent antitumor activity using H2L2 mice	7
Histone chaperone‐mediated co‐expression assembly of tetrasomes and nucleosomes	7
Analysis of the regulation of undecaprenyl diphosphate dephosphorylation in Escherichia coli	7
Metallodrugs: an approach against invasion and metastasis in cancer treatment	7
FEBS Open Bio: past, present and future	7
The splicing factor DHX38/PRP16 is required for ovarian clear cell carcinoma tumorigenesis, as revealed by a CRISPR‐Cas9 screen	7
Corrigendum to “Endoplasmic reticulum stress associated with lead (Pb)‐induced olfactory epithelium toxicity in an olfactory dark basal cell line” https://doi.org/10.1002/2211‐5463.13714	7
Cotton flower metabolites inhibit SARS‐CoV‐2 main protease	7
Intermittent induction of LEA peptide by lactose enhances the expression of insecticidal proteins in Bacillus thuringiensis	7
Revealing protein structures: crystallization of protein‐ligand complexes – co‐crystallization and crystal soaking	7
Functional parameters of spermatozoa obtained by a new selection device	7
Benefits of exercise on cognitive impairment in alcohol use disorder following alcohol withdrawal	7
Oxidative stress in the tumor microenvironment in gastric cancer and its potential role in immunotherapy	7
Retraction: Kinesin family member 3A stimulates cell proliferation, migration, and invasion of bladder cancer cells in vitro and in vivo	7
Report on the FEBS‐IUBMB‐ENABLE 1st International Molecular Biosciences PhD and Postdoc Conference	7
Mitochondrial complex IV defects induce metabolic and signaling perturbations that expose potential vulnerabilities in HCT116 cells	7
Ferritin heavy chain (FTH1) exerts significant antigrowth effects in breast cancer cells by inhibiting the expression of c‐MYC	7
On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469	7
The cryo‐EM structure of full‐length RAD52 protein contains an undecameric ring	7
Overexpressed Smurf1 is degraded in glioblastoma cells through autophagy in a p62‐dependent manner	6
High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer	6
Tyr76 is essential for the cold adaptation of a class II glutaredoxin 4 with a heat‐labile structure from the Arctic bacteriumSphingomonassp.	6
Characterization of the complete chloroplast genome of Rhodiola sachalinensis and comparative analysis with its congeneric plants	6
Front Cover	6
Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study	6
Issue Information	6
Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria	6
A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers	6
Learning objectives: an epiphany	6

Characterisation of a common hotspot variant in acute intermittent porphyria sheds light on the mechanism of hydroxymethylbilane synthase function	6
A brief overview of BNIP3L/NIX receptor‐mediated mitophagy	6
Intracellular protein crystallization in living insect cells	6
Talks	6
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Retraction statement: miR‐944 inhibits metastasis of gastric cancer by preventing the epithelial–mesenchymal transition via MACC1/Met/AKT signaling	6
CDK5 interacts with MST2 and modulates the Hippo signalling pathway	6
Biochemical characterization and gene structure analysis of the 24‐kDa glutathione transferase sigma from Taenia solium	6
Issue Information	6
Real‐world genomic landscape of colon and rectal cancer	6
Correction to “Characterization of the cHS4 insulator in mouse embryonic stem cells”	6
Liraglutide enhances the effect of checkpoint blockade in lung and liver cancers through the inhibition of neutrophil extracellular traps	6
The interplay between pathogens and Atg8 family proteins: thousand‐faced interactions	6
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Retraction statement: MicroRNA‐431 inhibits migration and invasion of hepatocellular carcinoma cells by targeting the ZEB1‐mediated epithelial–mesenchymal transition	6
Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024	6
Issue Information	6
Toll‐like receptor 9 signaling in chronic lymphocytic leukemia cell lines	6
RAB31 in glioma‐derived endothelial cells promotes glioma cell invasion via extracellular vesicle‐mediated enrichment of MYO1C	6
RETRACTION: MicroRNA‐498 Reduces the Proliferation and Invasion of Colorectal Cancer Cells via Targeting Bcl‐2	6
Issue Information	6
Exam‐level analysis of lecture capture viewing and student exam performance	6
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Mutations in RPS19 may affect ribosome function and biogenesis in Diamond Blackfan anemia	6
The dynamics of cell death patterns and regeneration during acute liver injury in mice	5
Issue Information	5
Structure prediction analysis of human core TIM23 complex reveals conservation of the protein translocation mechanism	5
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Malus pumila Mill. cv Annurca apple extract might be therapeutically useful against oxidative stress and patterned hair loss	5
hnRNP A1 and hnRNP C associate with miR‐17 and miR‐18 in thyroid cancer cells	5
MYPT1 inhibits the metastasis of renal clear cell carcinoma via the MAPK8/N‐cadherin pathway	5
Menthol‐like cooling compounds, including (R)‐(‐)‐carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K	5
Intrabacterial lipid inclusion‐associated proteins: a core machinery conserved from saprophyte Actinobacteria to the human pathogen Mycobacterium tuberculosis	5
Using a ‘Students as Partners’ model to develop an authentic assessment promoting employability skills in undergraduate life science education	5
Expression of a Crry/p65 is reduced in acute lung injury induced by extracellular histones	5
Acquired and intrinsic resistance to vemurafenib in BRAFV600E‐driven melanoma brain metastases	5
Development of a mouse embryonic stem cell model for investigating the functions of the linker histone H1‐4	5
Identification and analysis of short indels inducing exon extension/shrinkage events	5
Hesperidin enhances intestinal barrier function in Caco‐2 cell monolayers via AMPK‐mediated tight junction‐related proteins	5
On the difficulties of characterizing weak protein interactions that are critical for neurotransmitter release	5
Isolation and characterization of peritoneal microvascular pericytes	5
Issue Information	5
Flow cytometric resolution of yeast is affected by enzymatic treatment and culture media	5
HPV18 E6 inhibits α‐ketoglutarate‐induced pyroptosis of esophageal squamous cell carcinoma cells via the P53/MDH1/ROS/GSDMC pathway	5
Diagnostic and therapeutic targeting of pathological tau proteins in neurodegenerative disorders	5
Biochemical characterization of the human ubiquitous glucose‐6‐phosphatase in neutrophil granulocytes	5
Biological and clinical implications of metastasis‐associated circular RNAs in oesophageal squamous cell carcinoma	5
Knockdown of TMEM160 leads to an increase in reactive oxygen species generation and the induction of the mitochondrial unfolded protein response	5
Establishment of a risk score model for bladder urothelial carcinoma based on energy metabolism‐related genes and their relationships with immune infiltration	5
SMARCA4 mutations and expression in lung adenocarcinoma: prognostic significance and impact on the immunotherapy response	5
The role of RNA regulators, quorum sensing and c‐di‐GMP in bacterial biofilm formation	5
Beta cell regeneration upon magainin and growth hormone treatment as a possible alternative to insulin therapy	5
Biochemical and in silico identification of the active site and the catalytic mechanism of the circadian deadenylase HESPERIN	5
Feeder cells treated with ethanol can be used to maintain self‐renewal and pluripotency of human pluripotent stem cells	5
On the design of a constitutively active peptide asparaginyl ligase for facile protein conjugation	5
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WDHD1 is over‐expressed in nasopharyngeal carcinoma and may control the expression of ITGAV	5
Tryptophan‐sensing receptor GPR142 expression levels are directly regulated by proinflammatory cytokines in ghrelin‐producing cells	5
Diacylglycerol kinase ζ interacts with sphingomyelin synthase 1 and sphingomyelin synthase‐related protein via different regions	5
Nanoscale‐tipped wire array injections transfer DNA directly into brain cells ex vivo and in vivo	5
The protein tyrosine phosphatase PPH‐7 is required for fertility and embryonic development in C. elegans at elevated temperatures	4
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Titanium particles inhibit bone marrow mesenchymal stem cell osteogenic differentiation through the MAPK signaling pathway	4
The role of circular RNAs in regulating cytokine signaling in cancer	4
How hydrolytic exoribonucleases impact human disease: Two sides of the same story	4
Obesity‐induced oxidative stress and mitochondrial dysfunction negatively affect sperm quality	4
Corrigendum to: Identification and expression analysis of LEA gene family members in pepper (Capsicum annuum L.) https://doi.org/10.1002/2211‐5463.13718	4
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Phosphomimetic mutations near active sites of proteins in Thermus thermophilus suggest a widespread regulatory mechanism	4
Issue Information	4
RETRACTED: Fibronectin enhances tumor metastasis through B7‐H3 in clear cell renal cell carcinoma	4
Cardiovascular risk of dietary trimethylamine oxide precursors and the therapeutic potential of resveratrol and its derivatives	4
Oleanolic acid alleviates obesity‐induced skeletal muscle atrophy via the PI3K/Akt signaling pathway	4
Fluoxetine partially alleviates inflammation in the kidney of socially stressed male C57 BL/6 mice	4
Lipid dysmetabolism in ceruloplasmin‐deficient mice revealed both in vivo and ex vivo by MRI, MRS and NMR analyses	4
Withdrawal statement: [Liu, X., Qiao, L., Zhang, H., Zhang, C., Ding, R., Kang, J., Liu, Y., Lin, J. and Yan, X. (2023), Argonaute 2 regulates LPS‐induced inflammation in microglial BV2 cells by targe	4
Alcohol induces α2‐6sialo mucin O‐glycans that kill U937 macrophages mediated by sialic acid‐binding immunoglobulin‐like lectin 7 (Siglec 7)	4
Issue Information	4
Hippocampal tau‐induced GRIN3A deficiency in Alzheimer's disease	4
Retraction statement: microRNA‐497 inhibits cell proliferation and induces apoptosis by targeting YAP1 in human hepatocellular carcinoma	4
Retraction statement: Shao, L., Zhang, X. and Yao, Q. (2020), The F‐box protein FBXO11 restrains hepatocellular carcinoma stemness via promotion of ubiquitin‐mediated degradation of Snail. FEBS Open B	4
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Functional analysis of the N‐terminal region of acetylxylan esterase from Caldanaerobacter subterraneus subsp. tengcongensis	4
Comparative transcriptomics of the garden dormouse hypothalamus during hibernation	4
Corrigendum to: Determination of the optimal concentration and duration of C5aR antagonist application in an inflammatory model of human dental pulp cells	4
Microbiological investigation of pregnancies following vaginal radical trachelectomy using 16S rRNA sequencing of FFPE placental specimens	4
ARL2 is required for homologous recombination repair and colon cancer stem cell survival	4
Structures of distantly related interacting protein homologs are less divergent than non‐interacting homologs	4
Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells	4
Comparative genome analysis of three classical E. coli cloning strains designed for blue/white selection: JM83, JM109 and XL1‐Blue	4
Abstracts	4
Cylindracin, a Cys‐rich protein expressed in the fruiting body of Cyclocybe cylindracea, inhibits growth of filamentous fungi but not yeasts or bacteria	4
Accumulation of TERT in mitochondria exerts two opposing effects on apoptosis	4
Exploring gene regulatory interaction networks and predicting therapeutic molecules for hypopharyngeal cancer and EGFR‐mutated lung adenocarcinoma	4
Expression and purification of the receptor‐binding domain of SARS‐CoV‐2 spike protein in mammalian cells for immunological assays	4