Journal of Bone Oncology

Article	Citations
#15. Single-cell discovery and multi-omic characterization of therapeutic targets in multiple myeloma	184
Non-invasive MRI biomarkers for assessment of neoadjuvant chemotherapy response in osteosarcoma: Current techniques and clinical perspectives	45
Real-life use of bone-targeting agents for bone metastases in France between 2009 and 2018: Results of the OPTIMOS study	37
Senescence in the bone marrow microenvironment: A driver in development of therapy-related myeloid neoplasms	36
From bimodal to unimodal: The transformed incidence of osteosarcoma in the United States	30
Single Photon Emission Computed Tomography/X-ray Computed Tomography-based radiomics analysis for diagnosis of bone metastases in patients with breast cancer	26
MAT2A inhibits the ferroptosis in osteosarcoma progression regulated by miR-26b-5p	25
Risk factors and clinical impact of bone pain in patients with multiple myeloma – A prospective interdisciplinary study	24
Lipid metabolic reprogramming and associated ferroptosis in osteosarcoma: From molecular mechanisms to potential targets	24
Chinese expert consensus on the diagnosis and clinical management of medication-related osteonecrosis of the jaw	24
Identification of immunopeptides (pHLA) as candidate therapeutic targets in chondrosarcoma	22
Macrophage heterogeneity in bone metastasis	22
Predicting lung metastasis in high-grade osteosarcoma: The role of computed tomography angiography (CTA) signs with a focus on vascular wrapping and the intratumoral vascular network	21
Radiomics model based on MRI to differentiate spinal multiple myeloma from metastases: A two-center study	21
Demethylzeylasteral inhibits proliferation and metastasis of osteosarcoma cells by modulating the PI3K/AKT/Autophagy pathways	21
Questionable indication for postoperative radiotherapy after surgery for metastases of the major long bones: A single-centre cohort study of 552 fractures/526 patients	21
A multicenter, randomized, double-blind trial comparing LY01011, a biosimilar, with denosumab (Xgeva®) in patients with bone metastasis from solid tumors	20
Association of androgen receptor and tumour-infiltrating lymphocytes with bone recurrence in triple-negative breast cancer	20
Preoperative prediction of high-grade osteosarcoma response to neoadjuvant therapy based on a plain CT radiomics model: A dual-center study	20
Pain in patients with multiple inherited osteochondromas: Incidence and potential prognostic factors. A retrospective cohort study	19
#1. Acid ceramidase (ASAH1) is a key mediator of drug resistance in relapsed/refractory multiple myeloma	19
#41. Discovery of novel tubulin code in bone metastasis of breast cancer	19
#23. Elucidating the role of bone marrow stiffness in estrogen signaling in metastatic breast cancer to the bone	18
Comprehensive landscape of TGFβ-related signature in osteosarcoma for predicting prognosis, immune characteristics, and therapeutic response	18
Rotationplasty performed in adults versus minors: a comparative study of long-term quality of life, functional and biomechanical outcomes	18

Pathological fractures as an adverse prognostic factor in chondrosarcoma: Results of a systematic review, meta-analysis and institutional case series	18
#31. A Phase I/II trial of ATI-2231 with Phase Ia in advanced soild tumor malignancies followed by Phase Ib/II in combination with capecitabine in patients with hormone receptor-positive (HR+) and HER	17
#2. Homing of intestinal NK and Th1 cells to the tumor site restrains melanoma bone growth in a gut microbiome dependent manner	17
#6. Mechanical loading of breast cancer laden bones alters osteocyte mediated bone loss in vivo	16
Intraosseous conventional central chondrosarcoma does not metastasise irrespective of grade in pelvis, scapula and in long bone locations	15
#49. Complete estrogen-deprived athymic nude mice are susceptible to changes in metabolism and musculoskeletal function mediated by a high-fat diet	15
Integrative machine learning and multi-omics identify a centromere gene signature and validate B3GALT4 as a tumor suppressor in osteosarcoma	15
Zoledronic acid in metastatic castrate-sensitive prostate cancer: A state-of-the-art review	15
LncRNA SATB2-AS1 promotes tumor growth and metastasis and affects the tumor immune microenvironment in osteosarcoma by regulating SATB2	14
Targeting stromal p38MAPKalpha triggers innate-adaptive anti-tumor immunity and sensitizes metastatic breast cancer to immunotherapy	14
Incidence and radiotherapy treatment patterns of complicated bone metastases	14
Molecular imaging of bone metastasis	14
#14. Determining how prostate cancer cell heterogeneity promotes bone metastasis using fluid-walled microfluidics	14
Impact of myosteatosis on prognosis in multiple myeloma patients: A subgroup analysis of 182 cases and development of a nomogram	14
Long-term oncological and functional outcomes in patients with bone sarcomas in the proximal femur undergoing unplanned surgery: A single-center retrospective cohort study	14
Immune checkpoint inhibitors in bone metastasis: Clinical challenges, toxicities, and mechanisms	13
Reprogramming of glucose metabolism: Metabolic alterations in the progression of osteosarcoma	13
FemurTumorNet: Bone tumor classification in the proximal femur using DenseNet model based on radiographs	13
The roles of the FL/FLT3 axis in the development of cancer-induced bone pain mediated by prostate cancer	13
From imaging to omics: deep learning is bridging MRI and liquid biopsy in bone tumor diagnosis	13
Carbon fiber-reinforced peek versus titanium implants for the surgical treatment of spinal metastases: Evaluation of local disease control and quality of life	13
Mixed reality infrastructure based on deep learning medical image segmentation and 3D visualization for bone tumors using DCU-Net	12
#8. Radium-223 treated primary patient bone biopsy analysis: Macro to microscale analyses and dosimetry	12
Single-cell fixed RNA profiling of the osteosarcoma clinical Spectrum identifies ADAMTS12 and RNASE1 as key drivers of the metastatic niche	12
Multicenter study on atypical femoral fractures in patients with bone metastases taking bone- modifying agents	12
#51. High dimensional profiling of human prostate metastatic bone marrow microenvironment using mass cytometry	12
Latest developments in the pathobiology of Ewing sarcoma	12
The impact of comprehensive local therapy on treatment outcomes of non-small cell lung cancer with solitary skeletal oligometastasis	12
#50. Investigating the role of EphA2 in breast cancer bone metastasis	12
Efferocytosis-associated transcriptomic patterns characterize prognosis and immune landscape in osteosarcoma	11
#7. Downstream effects of Gli2 targeting on tumor-immune cell crosstalk in bone metastatic breast cancer	11
Bone metastasis in colorectal cancer: Pathophysiology, prognostic factors, survival outcomes, and treatment strategies – A comprehensive review	11
Bones and guts – Why the microbiome matters	11
Automatic classification of spinal osteosarcoma and giant cell tumor of bone using optimized DenseNet	11
#45. Fatty acid binding proteins may modulate myeloma in Fabp4/5 double knockout mouse	11
Molecular pathological insights into tumorigenesis and progression of giant cell tumor of bone	11
YBX1-interacting small RNAs and RUNX2 can be blocked in primary bone cancer using CADD522	11
Health- related quality of life after surgery for spinal metastases	10
Treatment of myeloma bone disease: When, how often, and for how long?	10
Does liquid nitrogen recycled autograft for treatment of bone sarcoma impact local recurrence rate? A systematic review	10
Circ_0051079 silencing inhibits the malignant phenotypes of osteosarcoma cells by the TRIM66/Wnt/β-catenin pathway in a miR-625-5p-dependent manner	10
Pexmetinib suppresses osteoclast formation and breast cancer induced osteolysis via P38/STAT3 signal pathway	10
COPB2 as a key regulator of cell growth in human osteosarcoma cells: Potential therapeutic target and prognostic indicator	10
Tenosynovial giant cell tumor of the hip: a systematic review and institutional case series with Meta-analysis of recurrence and patient-reported outcomes	10
Surgical Options for Aggressive Vertebral Hemangiomas：A case series, literature review and treatment recommendations	9
Cav3.2 T-Type calcium channels downregulation attenuates bone cancer pain induced by inhibiting IGF-1/HIF-1α signaling pathway in the rat spinal cord	9
Yin Yang 1 protein-activated N-acetyltransferase 10 drives cell malignant progression of osteosarcoma through ac4C acetylation of integrin β3	9
Diagnostic value of H3F3A mutation and clinicopathological features of giant cell tumours in non-long bones	9
Non-POEMS osteosclerotic multiple myeloma: Clinical characteristics and differential diagnosis	9
Dual-target neoadjuvant therapy with denosumab and sunitinib for giant cell tumor of bone: a sarcoma center experience	9

Malignant and metastatic giant cell tumors of bone; clinical course of primary or secondary malignant and pulmonary metastatic variants	9
The metastatic role of the CXCL10-CXCR3 axis and its therapeutic potential in osteosarcoma	9
A novel adjunctive diagnostic method for bone cancer: Osteosarcoma cell segmentation based on Twin Swin Transformer with multi-scale feature fusion	9
Deep hashing and attention mechanism-based image retrieval of osteosarcoma scans for diagnosis of bone cancer	8
Abaloparatide and paclitaxel combination therapy Improves bone volume and tumor burden in Bone-Metastatic breast cancer	8
Diagnosis of newly developed multiple myeloma without bone disease detectable on conventional computed tomography (CT) scan by using dual-energy CT	8
Incidence of malignant transformation in giant cell tumor of bone following denosumab therapy: a systematic review and meta-analysis	8
Osteofibrous dysplasia, osteofibrous Dysplasia-Like adamantinoma, and adamantinoma: A Single-center retrospective analysis	8
Determinants of tumor necrosis and its impact on outcome in patients with Localized osteosarcoma uniformly treated with a response adapted regimen without high dose Methotrexate– A retrospective insti	8
Feasibility and oncologic outcome of En bloc resection with intentional tumor transgression in primary spinal sarcoma: The Korean Society of Spinal Tumors multicenter study (KSST 2024–02)	8
Multimodal deep learning for bone tumor diagnosis with clinical imaging, pathology, and blood biomarkers	8
RGS1 stabilized by METTL3-mediated m6A modification promotes the tumorigenicity and macrophage M2 polarization in osteosarcoma	8
Groenlandicine enhances cisplatin sensitivity in cisplatin-resistant osteosarcoma cells through the BAX/Bcl-2/Caspase-9/Caspase-3 pathway	8
Chronic kidney disease and denosumab in metastatic bone disease: A multicenter Turkish cohort study on severe hypocalcemia, skeletal events, and survival	8
The 100 most cited papers on bone metastasis: A bibliometric analysis	7
An enhanced AlexNet-Based model for femoral bone tumor classification and diagnosis using magnetic resonance imaging	7
#13. 3D printed bioactive glasses porous scaffolds with high strength for the repair of long-bone segmental defects	7
Incidence patterns and trends of chordoma in the United States: a population-based analysis of over 6,000 cases	7
Diagnostic Innovations: Advances in imaging techniques for diagnosis and follow-up of multiple myeloma	7
Vitamin D decreases tumor cell growth and invasiveness in primary malignant bone tumors in vitro	7
AI diagnostics in bone oncology for predicting bone metastasis in lung cancer patients using DenseNet-264 deep learning model and radiomics	7
Auxiliary diagnosis of primary bone tumors based on Machine learning model	7
Radiographic imaging and diagnosis of spinal bone tumors: AlexNet and ResNet for the classification of tumor malignancy	7
The role of IL-1B in breast cancer bone metastasis	7
Pharmacologic Hedgehog inhibition modulates the cytokine profile of osteolytic breast cancer cells	7
Doxorubicin induces bone loss and modifies multiple cell populations in vivo – Implications for modelling of bone metastasis	6
Analysis of morbidity and mortality in patients with primary bone tumors who underwent sacrectomy: A systematic review	6
Tyrosine kinase inhibitors in osteosarcoma: Adapting treatment strategiesa	6
#12. Potential role of bone metastasis-associated fibroblasts in prostate cancer-induced bone pain	6
Essential genes analysis reveals small ribosomal subunit protein eS28 may be a prognostic factor and potential vulnerability in osteosarcoma	6
Differential expression of CD74 and C1QB in jaw versus long bone osteosarcoma: Insights from animal models, public datasets and clinical cohorts	6
Benign and malignant bone lesion diagnosis based on self-supervised and radiomics fusion using SPECT/CT images	6
Denosumab versus zoledronic acid in cases of surgically unsalvageable giant cell tumor of bone: A randomized clinical trial	6
Optimal timing for local ablative treatment of bone oligometastases in non-small cell lung cancer	6
Social determinants are associated with clinical presentation of acute pathological fracture in metastatic long-bone disease	6
BMS-794833 reduces anlotinib resistance in osteosarcoma by targeting the VEGFR/Ras/CDK2 pathway	6
Clinical applications of MRI-based artificial intelligence in spinal metastases: A systematic review	6
Changes in bone turnover markers in patients without bone metastases receiving immune checkpoint inhibitors: An exploratory analysis	5
EFEMP1 binds to STEAP1 to promote osteosarcoma proliferation and invasion via the Wnt/β-catenin and TGF-β/Smad2/3 signal pathways	5
Management of aromatase inhibitor-associated bone loss (AIBL) in women with hormone-sensitive breast cancer: An updated joint position statement of the IOF, CABS, ECTS, IEG, ESCEO, IMS, and SIOG	5
Emerging roles for stromal cells in bone metastasis	5
#43. Long-chain acyl-CoA synthetases support multiple myeloma cell proliferation, survival and mitochondrial function	5
Progression of vertebral fractures in metastatic melanoma and non-small cell lung cancer patients given immune checkpoint inhibitors	5
Management of bone metastasis with zoledronic acid: A systematic review and Bayesian network meta-analysis	5
Risk of fracture among lung cancer survivors by cancer treatment modality: A population-based retrospective cohort study	5
Is surgery without curettage effective for periacetabular Metastasis? Insights from a survival study of 93 patients	5
Development and validation of a biopsy-based model using tumor-associated neutrophils to predict neoadjuvant chemotherapy response in osteosarcoma: a large single-center retrospective cohort study	5
Mri-based habitat and peritumoral radiomics for predicting the proliferative activity of stromal cells in giant cell tumor of bone	5
Predicting bone metastasis risk of colorectal tumors using radiomics and deep learning ViT model	5
ICG-based NIR fluorescence imaging can help to detect residual giant cell tumor of bone after intralesional curettage: Results of two-year follow-up	5
CDK4/6 inhibitor and doxorubicin synergistically inhibit breast cancer bone metastasis and enhance T-cell targeted therapy	5
Metastatic bone disease in proximal femur. Outcome of surgical treatments. − Do we know what to do?	4
#21. PD-1 blockade induces bone loss and reduces bone strength in a breast cancer bone metastasis model	4
Automated measurement of lumbar pedicle screw parameters using deep learning algorithm on preoperative CT scans	4
Prevalence of low bone mineral density and risk of fractures in osteosarcoma and Ewing’s sarcoma survivors: A scoping review	4
Adipocytes and metabolism: Contributions to multiple myeloma	4
Bone tumor examination based on FCNN-4s and CRF fine segmentation fusion algorithm	4
Surgical management and outcome of Extra-adrenal myelolipomas at unusual locations: A report of 11 cases in a single center	4
#3. IL-17A supports osteoblasts to become cancer-associated fibroblasts in breast cancer bone metastases	4
Impact of quantitative CT texture analysis on the outcome of CT-guided bone biopsy	4
Single-cell RNA-seq reveals intratumoral heterogeneity in osteosarcoma patients: A review	4
Recombinant LGR4 extracellular domain attenuates osteoclastogenesis and prevents bone metastasis via RANKL inhibition	4
Modified OPTIModel with oligometastatic disease for the prediction of overall survival of patients with renal cell cancer and symptomatic long bone metastases	4
#5. Activating RET mutations in medullary thyroid cancer cells promotes osteoblastic bone metastasis by inhibiting osteoclastogenesis and stimulating osteoblast activity	4
Bone-derived excess TGF-ß release is associated with cognitive dysfunction due to oxidation of RyR, Ca2+ leak and mitochondrial dysfunction	4
#35. Defining short-form RON mediated anti-tumor immunity in breast cancer bone metastasis	4
Predicting lung cancer bone metastasis using CT and pathological imaging with a Swin Transformer model	3
#39. Bone-derived Dickkopf-related protein 1 supports primary breast cancer growth and alters hematopoiesis	3
The phosphatase CTDSPL2 promotes proliferation, invasion, metastasis and regorafenib resistance in osteosarcoma	3
Clinically aligned whole-body MRI segmentation of skeletal metastases via Supervised Anatomical Pretraining	3
Analysis of 121 cases of osteosarcoma of jaws reported in the literature over the past two decades: a scoping review	3
Efficacy of replacing actinomycin-D with carboplatin in Ewing sarcoma consolidation treatment: Single-center experience	3
Imaging evaluation of blood supply changes after chemotherapy of osteosarcoma and its correlation with tumor necrosis rate	3
#4. Elucidating the effect of glutamine metabolism in breast-to-bone metastasis	3
Single-cell transcriptional profiling in osteosarcoma and the effect of neoadjuvant chemotherapy on the tumor microenvironment	3
#38. Cholesterol increases bone marrow tumour burden in myeloma in vivo and promotes myeloma cell viability and bortezomib resistance ex vivo	3
CDK4/6 inhibitor ribociclib and doxorubicin combination treatment inhibits breast cancer bone metastasis and enhances T-cell targeted therapy	3
Therapeutic approaches in patients with bone metastasis due to endometrial carcinoma – A systematic review	3
Application of responsive nano-drug carriers in bone tumor chemotherapy	3
Analysis of intercellular communication in the osteosarcoma microenvironment based on single cell sequencing data	3

Epigenetic control of the vicious cycle	3
#24. Mechanical loading-induced changes to the bone microenvironment control bone metastatic breast cancer lesions	3
-AI-assisted diagnostic potential of CT in bone oncology and its impact on clinical decision-making for intensive care	3
MUTARS® Humero pro Femur replacement: A novel reconstructive procedure after malignant bone tumor resection of the femur in young children	3
Psychosocial impact of COVID-19 pandemic on patients with solid malignancies and bone metastases (PsyCO-B): a multicentre prospective observational study	3
RNA 5-methylcytosine status is associated with DNMT2/TRDMT1 nuclear localization in osteosarcoma cell lines	3
Bone density measurement in patients with spinal metastatic tumors using chest quantitative CT deep learning model	3
Comprehensive analysis of cancer and non-cancer mortality in patients with bone metastases: A population-based study	3
Exploring bone-tumor interactions through 3D in vitro models: Implications for primary and metastatic cancers	3
#47. Chemotherapy-induced microenvironmental changes promote dormant breast cancer cell growth in the adipose tissue	2
Health-related quality of life and physical activity in children with Multiple Osteochondromas	2
The validity of the distress thermometer in patients with musculoskeletal tumors	2
The risk of pathological fractures after intralesional curettage in Atypical Cartilaginous Tumours: A retrospective cohort study	2
Bone cement implantation syndrome in patients with cemented endoprostheses for metastatic bone disease in the femur	2
Comprehensive diagnostic model for osteosarcoma classification using CT imaging features	2
Metastatic renal cell carcinoma: risk of rapid progression to pathological fractures and factors influencing post-treatment survival – a Swedish Nationwide cohort study	2
Pelvic bone tumor segmentation fusion algorithm based on fully convolutional neural network and conditional random field	2
Reversine inhibits proliferation and induces apoptosis of human osteosarcoma cells through targeting MEK1	2
Decoding the immune landscape in Ewing sarcoma pathogenesis: The role of tumor infiltrating immune cells and immune milieu	2
Assessing the mechanism of osteosarcoma induced by long-term PET exposure: prediction from combined network toxicology, machine learning and molecular docking	2
Senolytics deplete senescent osteocytes and improve bone health in metastatic breast cancer	2
Soft tissue recurrence in giant cell tumor of Bone: A comprehensive review of pathogenesis, imaging features, and clinical management	2
The METTL3/TGF-β1 signaling axis promotes osteosarcoma progression by inducing MSC differentiation into CAFs via m6A modification	2
#30. Fractures in metastatic hormone-sensitive prostate cancer (mHSPC). Results from two phase 3 trials from the STAMPEDE platform	2
#29. A novel control mechanism of endosomal trafficking in bone metastatic breast cancer cells	2
Cutting edge developments in bone oncology – Highlights from the Cancer and Bone Society 2024 annual meeting	2
Lipopolysaccharide-binding protein expression is associated to the metastatic status of osteosarcoma patients	2
Clinicopathological features and survival disparities between axial and appendicular skeletal Angiosarcoma: A SEER-based analysis using competing risk models	2
Chondroblastoma of the femoral head:current and future therapeutic options	2
Surgical margin assessment of bone tumours: A systematic review of current and emerging technologies	2